Electroacupuncture-traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy

Abstract

The invention relates to the technical field of traditional Chinese medicine treatment, and provides an electro-acupuncture-traditional Chinese medicine sequential therapy for treating chemotherapy induced peripheral neuropathy, collaborative treatment is realized through combination of electro-acupuncture and layered traditional Chinese medicine soaking and washing, the electro-acupuncture selects eight-wind, eight-evil, hegu, taichong, external guan, Zusanli, Sanyinjiao and Tiangui acupoints, and the electro-acupuncture selects a traditional Chinese medicine for treating chemotherapy induced peripheral neuropathy. Connecting an electric acupuncture apparatus to the Zusanli acupoint and the Sanyinjiao acupoint after the needle is inserted to obtain air, and retaining the needle by adopting sparse and dense waves; traditional Chinese medicine soaking and washing are graded according to illness conditions, radix astragali and cassia twig five-material decoction is added or subtracted for mild illness, blood circulation promoting and collateral dredging decoction is used for severe illness, and after the medicinal materials are soaked and decocted, liquid medicine is taken and cooled to soak hands and feet. According to the therapy, the synergistic effect of dredging channels and collaterals, improving microcirculation and repairing nerves is formed through electro-acupuncture and meridian dredging and traditional Chinese medicine soaking, washing, meridian warming and blood activating, adverse reactions of oral medicine are avoided, the numbness and pain symptoms of hands and feet of CIPN patients are remarkably improved, the life quality is improved, and a safe and efficient traditional Chinese and western medicine combined treatment scheme is provided for CIPN.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of traditional Chinese medicine treatment, in particular to an electro-acupuncture and traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy. BACKGROUND

[0002] The incidence of chemotherapy-induced peripheral neuropathy (CIPN) is as high as 90%, and patients often have symptoms such as numbness and pain in hands and feet, which seriously affects chemotherapy compliance and quality of life. Currently, Western medicine mainly uses oral drugs such as duloxetine and pregabalin for treatment, but most of them have limited efficacy, and gastrointestinal reactions such as nausea and vomiting are common after chemotherapy in tumor patients, further increasing the difficulty of taking medicine. Traditional Chinese medicine classifies CIPN as "Bi syndrome", and believes that the pathogenesis is that chemotherapy drugs damage the collaterals, causing blood stasis and meridian malnutrition. Traditional Chinese medicine treatment mostly uses separate acupuncture, traditional Chinese medicine soaking or combined oral drugs, but due to the lack of sequential synergy mechanism, the efficacy is difficult to break through. In the prior art, the treatment means for CIPN have the limitations of insufficient efficacy, many adverse reactions or complex operation, and there is an urgent need for safe and efficient innovative therapies. SUMMARY

[0003] In view of the deficiencies of the prior art, the present application provides an electro-acupuncture and traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy, which solves the problems of the current Western medicine treatment of chemotherapy-induced peripheral neuropathy having very little effect and patients having difficulty taking medicine due to gastrointestinal reactions, and the limited effect of traditional Chinese medicine treatment such as separate acupuncture or traditional Chinese medicine soaking.

[0004] To achieve the above purpose, the present application is implemented by the following technical scheme: an electro-acupuncture and traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy, comprising:

[0005] Electro-acupuncture treatment, specifically comprising the following steps:

[0006] S1. Selecting acupoints: eight wind acupoints, eight evil acupoints, Hegu acupoint, Taichong acupoint, Waiqiang acupoint, Zusanli acupoint, Sanyinjiao acupoint and Juegu acupoint;

[0007] S2. Operation: after inserting the needle, apply flat supplement and flat draining manipulation until the patient gets qi, connect the electro-acupuncture instrument at the ipsilateral Zusanli acupoint and Sanyinjiao acupoint, use dense and sparse waves, and leave the needle for 30 minutes;

[0008] Layered traditional Chinese medicine soaking, specifically comprising the following steps:

[0009] a. Selection of prescription:

[0010] Mild: Huangqi Guizhi Wuwu Decoction, containing 15-25g of Guizhi, 20-40g of Huangqi, 15-25g of Baishao, 10-15g of Shengjiang and 10-12 pieces of Dazao;

[0011] Severe cases: Blood-activating and meridian-clearing decoction, containing cinnamon twig 15-25g, eupatorium 25-35g, red peony root 10-20g, dried ginger 8-12g, clematis root 25-35g, chicken blood vine 25-35g, clematis root 25-35g, mugwort leaf 25-35g, luffa fruit 10-20g, chuanxiong rhizome 8-12g, and safflower 8-12g;

[0012] b. Procedure: After soaking the Chinese herbs for 30 minutes, decoct them, filter out 3000-5000ml of the decoction, cool it to 39℃-42℃, and soak the hands and feet until the wrists and ankles are submerged.

[0013] Preferably, in S2, the sparse and dense waves of the electroacupuncture device alternately output 2Hz low-frequency and 100Hz high-frequency pulses with a fixed duty cycle.

[0014] Preferably, the formula ratio of the blood-activating and collateral-clearing decoction in a is: 20g of cinnamon twig, 30g of Lycopus lucidus, 15g of red peony root, 10g of dried ginger, 30g of Clematis chinensis, 30g of Spatholobus suberectus, 30g of Clematis armandii, 30g of Artemisia argyi, 15g of Liquidambar formosana, 10g of Ligusticum chuanxiong, and 10g of safflower.

[0015] Preferably, the modified Huangqi Guizhi Wuwu Decoction in a contains 30g of Astragalus membranaceus, 20g of Cinnamomum cassia, 15g of Paeonia lactiflora, 10g of Zingiber officinale, and 10 jujubes.

[0016] Preferably, the soaking time in step b is 30 to 40 minutes.

[0017] Preferably, the electroacupuncture treatment is performed 3 times a week, with 7 treatments constituting one course, for a total of 12 weeks.

[0018] Preferably, the treatment cycle for the herbal soak is once a day, with 7 times constituting one course of treatment, for a total of 12 weeks.

[0019] This invention provides an electroacupuncture-traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy. It has the following beneficial effects:

[0020] 1. This invention uses electroacupuncture to stimulate specific acupoints such as Bafeng and Baxie, combined with a dense-sparse wave electroacupuncture device to enhance the continuous effect of acupuncture sensation. This can dredge the meridians and collaterals, regulate the function of nerves and blood vessels, and at the same time, according to the severity of the condition, use Huangqi Guizhi Wuwu Decoction or Huoxue Tongluo Decoction for soaking in Chinese medicine. The medicine is absorbed through the skin and exerts the effects of warming the meridians and activating blood circulation, improving microcirculation. The sequential combination of the two forms a synergistic effect of "dredging the meridians and collaterals and nourishing the tendons and muscles", which can effectively promote the repair of nerve function, reduce the interruption of chemotherapy, significantly improve the symptoms of numbness and pain in the hands and feet, and improve the quality of life.

[0021] 2. The therapy of this invention adopts traditional Chinese medicine external treatment methods throughout the process, avoiding the stimulation of the digestive tract by oral drugs. It has high safety and few adverse reactions, and is especially suitable for cancer patients who cannot tolerate oral medication due to nausea and vomiting after chemotherapy. It provides an efficient and safe treatment paradigm for CIPN. DETAILED DESCRIPTION

[0022] The technical solutions in the embodiments of the present application will be clearly and completely described below in conjunction with the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by a person of ordinary skill in the art without creative effort belong to the protection scope of the present application.

[0023] Embodiment 1

[0024] The embodiments of the present application provide an electroacupuncture-traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy. For patients with mild symptoms, the electroacupuncture-traditional Chinese medicine sequential therapy comprises the following steps.

[0025] Electroacupuncture treatment

[0026] S1. Selecting acupoints: select the following acupoints in turn: Bafeng acupoint, Baxie acupoint, Hegu acupoint, Taichong acupoint, Waiguan acupoint, Zusanli acupoint, Sanyinjiao acupoint and Juegu acupoint.

[0027] S2. Operation: use a acupuncture needle with a suitable specification, adopt a flat reinforcing and reducing manipulation after the acupuncture needle is inserted, until the patient has a qi reaction, then connect the Zusanli acupoint and the Sanyinjiao acupoint on the same side with an electroacupuncture instrument, the electroacupuncture instrument outputs dense and sparse waves, alternately outputs 2Hz low-frequency and 100Hz high-frequency pulses with a fixed duty ratio, and the acupuncture needle is left for 30 minutes.

[0028] Layered traditional Chinese medicine soaking

[0029] a. Prescription selection: Huangqi Guizhi Wuwu Decoction plus-minus is selected, and the specific components are Huangqi 30g, Guizhi 20g, Baishao 15g, Shengjiang 10g and Dazao 10 pieces.

[0030] b. Operation: put the above-mentioned traditional Chinese medicinal materials into a container, soak for 30 minutes, and then decoct. After decoction is completed, filter 4000ml of medicinal liquid, wait for the medicinal liquid to cool down to 40℃, let the patient soak hands and feet, ensure that the wrist and ankle joints are submerged in the medicinal liquid, and the soaking time is 35min.

[0031] Treatment cycle and interval: the electroacupuncture treatment is performed 3 times a week, 7 times are a course of treatment, and the total is 12 weeks; the traditional Chinese medicine soaking is performed once a day, 7 times are a course of treatment, and the total is 12 weeks; if the electroacupuncture treatment and the traditional Chinese medicine soaking are performed on the same day, the treatment interval of the electroacupuncture treatment and the traditional Chinese medicine soaking is controlled to be within 2h.

[0032] Therapeutic effect: Ms. Li is a patient with mild peripheral neuropathy after chemotherapy, showing mild numbness and tingling at the end of hands and feet, and a slight increase in sensory threshold. After 12 weeks of sequential treatment of electroacupuncture and Huangqi Guizhi Wuwu Decoction, the numbness and tingling sensation of the hands and feet were significantly reduced, the sensory function score was improved by 40% compared with before treatment, the tactile and temperature sensation were basically restored to normal, and the electromyography showed that the nerve conduction velocity was increased by 15% compared with before treatment. The daily life was basically not affected by the symptoms, and there was no skin allergy or acupuncture-related adverse reactions during the treatment.

[0033] Example 2

[0034] The embodiment of the present application provides an electroacupuncture and traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy, which comprises the following steps:

[0035] Electroacupuncture treatment

[0036] S1. Selecting acupoints: accurately selecting Bafeng acupoint, Bazhe acupoint, Hegu acupoint, Taichong acupoint, Waiguan acupoint, Zusanli acupoint, Sanyinjiao acupoint and Juegu acupoint.

[0037] S2. Operation: insert the needle according to the needle operation specification, apply flat supplement and flat reducing manipulation to make the patient get qi, connect the ipsilateral Zusanli acupoint and Sanyinjiao acupoint with an electroacupuncture instrument, set the electroacupuncture instrument to fixed duty cycle to alternately output 2Hz low frequency and 100Hz high frequency pulse dense and sparse waves, and leave the needle for 30 minutes.

[0038] Layered traditional Chinese medicine soaking

[0039] a. Prescription selection: adopt Huoxuetongluo Decoction, and the component ratio is 20g of Guizhi, 30g of Zelan, 15g of Chishao, 10g of Ganjiang, 30g of Tougucao, 30g of Jixueteng, 30g of Weilingxian, 30g of Aiyeh, 15g of Lulutong, 10g of Chuanxiong and 10g of Honghua.

[0040] b. Operation: soak the medicinal materials for 30 minutes, decoct, filter 4500ml of medicinal liquid, cool to 39℃, and let the patient soak hands and feet, so that the liquid covers the wrist and ankle joints, and the soaking time is 40 minutes.

[0041] Treatment cycle and interval: electroacupuncture treatment is performed 3 times a week, 7 times as a course, and a total of 12 weeks; traditional Chinese medicine soaking is performed once a day, 7 times as a course, and a total of 12 weeks; if the electroacupuncture treatment and the traditional Chinese medicine soaking are performed on the same day, the time interval between the electroacupuncture treatment and the traditional Chinese medicine soaking is not more than 2 hours.

[0042] Treatment Results: Mr. Wang presented with persistent and severe pain in his hands and feet, loss of sensation, and muscle atrophy. His CTCAE score was 3. After treatment with electroacupuncture combined with a blood-activating and meridian-clearing decoction, his visual analog scale (VAS) score for pain decreased from 7.5 to 3.0. The area of ​​numbness in his hands and feet decreased by 60%, and his muscle strength improved by 2 grades compared to before treatment. After 8 weeks of treatment, he was able to independently perform light fist clenching and toe movements. At 12 weeks, electromyography showed signs of repair of myelin sheath damage. Although he experienced a slight burning sensation in the local skin at the beginning of treatment, his overall tolerance was good, and his ability to take care of himself improved significantly.

[0043] Example 3:

[0044] This invention provides an electroacupuncture-traditional Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy, for conventional patients, including:

[0045] Electroacupuncture

[0046] S1. Select acupoints: Accurately locate and select the following acupoints: Bafeng, Baxie, Hegu, Taichong, Waiguan, Zusanli, Sanyinjiao, and Juegu.

[0047] S2. Procedure: After inserting the needle, use the even tonifying and reducing technique to induce the patient to obtain Qi. Connect the Zusanli and Sanyinjiao acupoints on the same side to the electroacupuncture device. The electroacupuncture device outputs alternating 2Hz low-frequency and 100Hz high-frequency pulsed dense and sparse waves with a fixed duty cycle. Retain the needles for 30 minutes.

[0048] Layered Chinese herbal soak

[0049] a. Prescription selection: Based on the patient's actual symptoms, if the symptoms are mild, use the modified Huangqi Guizhi Wuwu Decoction, containing 30g of Astragalus membranaceus, 20g of Cinnamomum cassia, 15g of Paeonia lactiflora, 10g of Zingiber officinale, and 10 jujubes; if the symptoms are severe, use Huoxue Tongluo Decoction, containing 20g of Cinnamomum cassia, 30g of Lycopus lucidus, 15g of Paeonia lactiflora, 10g of Zingiber officinale, 30g of Clematis chinensis, 30g of Caulis Spatholobi, 30g of Clematis armandii, 30g of Artemisia argyi, 15g of Liquidambar formosana, 10g of Ligusticum chuanxiong, and 10g of Carthamus tinctorius.

[0050] b. Procedure: Soak the selected Chinese medicinal materials for 30 minutes, then decoct them and filter out 3500ml of the decoction. When the temperature of the decoction drops to 42℃, let the patient soak their hands and feet in the decoction until the wrists and ankles are submerged. The soaking time is 30 minutes.

[0051] Treatment cycle and interval: Electroacupuncture treatment is performed 3 times a week, with 7 treatments constituting one course of treatment, lasting 12 weeks; herbal soaking is performed once a day, with 7 treatments constituting one course of treatment, lasting 12 weeks; if electroacupuncture treatment and herbal soaking are performed on the same day, the interval between electroacupuncture treatment and herbal soaking should be controlled at 1.5 hours.

[0052] Treatment Outcomes: Ms. Zhou experienced moderate numbness in her hands and feet, paresthesia, and gait instability, with symptoms lasting 6-12 weeks. Treatment was tailored to symptom stratification; a blood-activating and meridian-clearing decoction was used for severe cases, while a modified Huangqi Guizhi Wuwu decoction was used for mild cases. After 12 weeks of treatment, her neuropathy disability score (DN4) decreased from 10 to 4, her vibration perception threshold decreased by 30%, and the number of gait stability test errors decreased by 50%. No skin ulceration occurred during the herbal soaking treatment. Local tingling and numbness after electroacupuncture lasted 2-3 hours, which is considered a normal "deqi" response. The overall symptom improvement rate was 75%, and her daily activities were largely restored.

[0053] Example 4:

[0054] This invention provides a sequential therapy for treating chemotherapy-induced peripheral neuropathy by individually adjusting the intensity of electroacupuncture stimulation, comprising:

[0055] Electroacupuncture

[0056] S1. Select acupoints: Bafeng, Baxie, Hegu, Taichong, Waiguan, Zusanli, Sanyinjiao and Juegu.

[0057] S2. Operation: After inserting the needle, apply the even tonifying and reducing technique until the patient obtains Qi. Connect the electroacupuncture device to the Zusanli and Sanyinjiao acupoints on the same side, using a sparse-dense wave. Set the initial current intensity to 60% of the patient's tolerance, and increase it by 10% every 5 minutes until the patient's maximum tolerance is reached. Retain the needles for 30 minutes. The electroacupuncture device alternately outputs 2Hz low-frequency and 100Hz high-frequency pulses with a fixed duty cycle.

[0058] Layered Chinese herbal soak

[0059] a. Prescription selection: If the patient's symptoms are mild, Huangqi Guizhi Wuwu Decoction with modifications is selected, consisting of Astragalus membranaceus 35g, Cinnamomum cassia 22g, Paeonia lactiflora 18g, Zingiber officinale 12g and jujube 12 pieces; if the symptoms are severe, Huoxue Tongluo Decoction is selected, consisting of Cinnamomum cassia 22g, Lycopus lucidus 28g, Paeonia lactiflora 18g, Zingiber officinale 9g, Clematis chinensis 32g, Spatholobus suberectus 32g, Clematis chinensis 32g, Artemisia argyi 32g, Liquidambar formosana 18g, Ligusticum chuanxiong 9g and Carthamus tinctorius 9g.

[0060] b. Procedure: After soaking the Chinese medicine for 30 minutes, decoct it, filter out 4200ml of the decoction, cool it to 41℃, and soak the hands and feet until the wrists and ankles are submerged. The soaking time is 38 minutes.

[0061] Treatment cycle and interval: Electroacupuncture treatment is performed 3 times a week, with 7 treatments constituting one course of treatment, for a total of 12 weeks; herbal soaking is performed once a day, with 7 treatments constituting one course of treatment, for a total of 12 weeks; the interval between electroacupuncture treatment and herbal soaking is 1.8 hours.

[0062] Treatment effect: Mr. Zhang has obvious individual differences in tolerance to electroacupuncture stimulation. The initial 60% tolerance intensity is gradually increased to the maximum tolerance value. The remission rate of hand and foot numbness is improved by 30% compared with the fixed intensity group. Sensory function improves at the 4th week, and the nerve conduction velocity is restored to 80% of the pre-chemotherapy level at the 12th week. The dynamic adjustment of current intensity scheme significantly reduces the adverse rate of electroacupuncture tolerance, and the patient's subjective satisfaction reaches 92%. In particular, the frequency of night pain is reduced from 5 times a week to 1 time, and the sleep quality is also improved.

[0063] Example 5:

[0064] The embodiment of the present application provides a comprehensive sequential therapy for treating chemotherapy-induced peripheral neuropathy combined with auxiliary physiotherapy, comprising:

[0065] Electroacupuncture treatment

[0066] S1. Select acupoints: eight wind acupoints, eight evil acupoints, Hegu acupoint, Taichong acupoint, Waiqiang acupoint, Tuisi acupoint, Sanyinjiao acupoint and Juegu acupoint.

[0067] S2. Operation: After needle insertion, perform flat supplement and flat draining manipulation until the patient gets qi. Connect the electroacupuncture instrument to the ipsilateral Tuisi acupoint and Sanyinjiao acupoint. Use dense and sparse waves, and leave the needle for 30 minutes. The electroacupuncture instrument alternately outputs 2Hz low frequency and 100Hz high frequency pulses with a fixed duty cycle.

[0068] Layered traditional Chinese medicine soaking

[0069] a. Prescription selection: For mild patients, use Huangqi Guizhi Wuwu Decoction with modifications, containing Huangqi 28g, Guizhi 23g, Baishao 16g, Shengjiang 11g and Dazao 11 pieces. For severe patients, use Huoxue Tongluo Decoction, containing Guizhi 23g, Zelan 32g, Chishao 17g, Ganjiang 11g, Tougucao 28g, Jixueteng 28g, Weilingxian 28g, Yiyeh 28g, Lulutong 17g, Chuanqiong 11g and Honghua 11g.

[0070] b. Operation: After soaking in traditional Chinese medicine for 30 minutes, decoct, filter 3800ml of medicinal liquid, cool to 40℃, soak hands and feet until the wrist and ankle joints are submerged, and the soaking time is 36 minutes.

[0071] Auxiliary physiotherapy: Between electroacupuncture treatment and traditional Chinese medicine soaking, 15 minutes of infrared radiation physiotherapy for the hands and feet is added, the irradiation distance is kept at 30cm, and the temperature is set to 45℃.

[0072] Treatment cycle and interval: Electroacupuncture treatment is performed 3 times a week, 7 times as a course, and a total of 12 weeks. Traditional Chinese medicine soaking is performed once a day, 7 times as a course, and a total of 12 weeks. The treatment interval of electroacupuncture treatment and traditional Chinese medicine soaking is controlled to be within 1.5 hours, and the auxiliary physiotherapy is arranged in the interval period.

[0073] Treatment effect: Mr. Wang received hand and foot irradiation between electroacupuncture and traditional Chinese medicine soaking. After treatment, microcirculation detection showed that the blood flow of the skin of the hands and feet increased by 60%, and the transdermal absorption rate of the effective components of traditional Chinese medicine increased by 25%. Clinical observation showed that the relief time of numbness and pain was 1 week earlier than that of simple sequential therapy. The symptom improvement rate was 60% at 6 weeks of treatment, and the neurological function score reached 90% at 12 weeks. There was no skin burn during infrared therapy. The combined treatment regimen had a more significant effect on chemotherapy patients with peripheral neuropathy combined with diabetes, and the level of AGEs protein, a risk marker for foot ulcers, decreased by 35%.

[0074] The five groups of examples adjust nerve conduction by electroacupuncture stimulation of specific acupoints, combined with layered traditional Chinese medicine soaking, forming a synergistic effect of "dredging meridians - improving microcirculation - repairing nerves". The results show that: light patients can obtain good nerve function repair through the basic regimen, with the best treatment course tolerance; severe patients need to strengthen the compatibility of blood-activating and stasis-removing traditional Chinese medicine and prolong the soaking time, and the efficacy is highly related to the treatment course compliance; individualized electroacupuncture intensity adjustment can significantly improve treatment comfort and onset speed, especially for patients with abnormal sensory threshold; auxiliary infrared therapy promotes drug penetration through thermal effect, and has a synergistic effect on patients with microcirculation disorders. The overall effective rate of this sequential therapy is 85% to 92%, and the core advantage is to accurately adjust the prescription, stimulation parameters and auxiliary means according to the disease classification, and it has good safety with an adverse reaction rate of <5%, providing a standardized and individualized combined Chinese and Western medicine treatment paradigm for chemotherapy-induced peripheral neuropathy.

[0075] Although embodiments of the present application have been shown and described, it is to be understood that various modifications, substitutions, replacements and changes can be made to these embodiments without departing from the principles and spirit of the present application, and the scope of the present application is defined by the appended claims and their equivalents.

Claims

1. An electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy, characterized in that, The method comprises the following steps: The electro-acupuncture treatment comprises the following steps: S1. Selecting acupoints: eight-wind acupoints, eight-evil acupoints, Hegu acupoint, Taichong acupoint, Waiqiang acupoint, Zusanli acupoint, Sanyinjiao acupoint and Juegu acupoint; S2. Operation: After the needle is inserted, the flat supplementing and draining manipulation is performed until the patient feels qi, and the electro-acupuncture instrument is connected to the ipsilateral Zusanli acupoint and Sanyinjiao acupoint, the sparse-dense wave is adopted, and the needle is retained for 30 minutes; Layered traditional Chinese medicine soaking, specifically comprising the following steps: a. Prescription selection: Mild: Huangqi Guizhi Wuwu Decoction, containing 15-25g of Guizhi, 20-40g of Huangqi, 15-25g of Baishao, 10-15g of Shengjiang and 10-12 pieces of Dazao; Severe: Huoxue Tongluo Decoction, containing 15-25g of Guizhi, 25-35g of Zelan, 10-20g of Chishao, 8-12g of Ganjiang, 25-35g of Tougucao, 25-35g of Jixueteng, 25-35g of Weilingxian, 25-35g of Aiyeh, 10-20g of Lulutong, 8-12g of Chuanmiao and 8-12g of Honghua; b. Operation: After the traditional Chinese medicine is soaked for 30 minutes, it is decocted, 3000-5000ml of medicinal liquid is filtered, and the temperature is lowered to 39-42℃, and the hands and feet are soaked until the wrist and ankle joints are submerged.

2. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The sparse-dense wave of the electro-acupuncture instrument in S2 is alternately outputted at a fixed duty ratio of 2Hz low frequency and 100Hz high frequency pulse.

3. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The Huoxue Tongluo Decoction in a comprises Guizhi 20g, Zelan 30g, Chishao 15g, Ganjiang 10g, Tougucao 30g, Jixueteng 30g, Weilingxian 30g, Aiyeh 30g, Lulutong 15g, Chuanmiao 10g and Honghua 10g.

4. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The Huangqi Guizhi Wuwu Decoction in a comprises Huangqi 30g, Guizhi 20g, Baishao 15g, Shengjiang 10g and Dazao 10 pieces.

5. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The soaking time in b is 30-40 minutes.

6. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The treatment cycle of the electro-acupuncture treatment is 3 times per week, 7 times as a course of treatment, and a total of 12 weeks.

7. The electroacupuncture-Chinese medicine sequential therapy for treating chemotherapy-induced peripheral neuropathy according to claim 1, characterized in that, The treatment cycle of the traditional Chinese medicine soaking is 1 time per day, 7 times as a course of treatment, and a total of 12 weeks.