Rosa chinensis leaf gloss whole genome SNP molecular marker combination and application thereof

Abstract

The invention discloses a Chinese rose leaf gloss whole genome SNP molecular marker combination and application thereof, the SNP molecular marker combination comprises 4746 SNP sites distributed on 14 chromosomes of a Chinese rose, and 4746 SNP markers significantly related to leaf gloss are screened by analyzing 358 parts of Chinese rose re-sequencing data and distributed on the 14 chromosomes. A liquid-phase gene chip is designed on the basis of the SNP loci, gene detection can be carried out in the seedling stage of the Chinese rose, and the leaf gloss character can be predicted in advance. Compared with a traditional breeding method, the method has the advantages of high throughput detection, low cost, shortened breeding period and the like, the breeding efficiency can be remarkably improved, the cultivation of a new variety of Chinese rose with good glossiness is accelerated, the requirement of the market for high-quality Chinese rose is met, and the development of the flower industry is promoted.

Description

Technical Field

[0001] This invention relates to the field of molecular breeding technology, and in particular to a genome-wide SNP molecular marker combination for rose leaf gloss and its application. Background Technology

[0002] As a world-renowned ornamental flower, the luster of the rose's leaves plays an indispensable role in enhancing its overall ornamental value. Glossy leaves not only make the plant appear brighter and more vibrant but also complement the flowers, greatly enhancing the rose's aesthetic appeal. In landscaping, interior decoration, and garden arrangements, roses with glossy leaves are more attractive and popular in the market, satisfying people's diverse needs for flower appreciation and creating higher economic value.

[0003] However, the current breeding of new rose varieties with glossy leaves mainly relies on traditional breeding methods, which, combined with artificial selection, suffer from problems such as high workload, long cycle, and low efficiency. To improve the efficiency and accuracy of rose breeding, molecular marker-assisted breeding technology has emerged. SNPs (single nucleotide polymorphisms), as the most widely used molecular markers, play an important role in molecular marker-assisted breeding. In recent years, genome-wide selection breeding technology has developed rapidly. By constructing training sets of genotypes and agronomic traits, it can predict the agronomic traits of new materials, thereby completing the selection process at the seed or seedling stage, greatly saving the screening time after field planting and accelerating the breeding process.

[0004] Nevertheless, existing technologies still have shortcomings in the screening and application of SNP loci related to rose leaf gloss. Therefore, this invention aims to provide a genome-wide SNP locus combination, probe, chip, and its application that can accurately predict rose leaf gloss. By performing gene testing on rose seedlings at an early stage, plants with ideal leaf gloss traits can be quickly screened, thereby shortening the breeding cycle and accelerating the cultivation of new rose varieties with good gloss, meeting the market demand for high-quality roses.

[0005] Currently, there is a lack of efficient and accurate genome-wide SNP molecular marker combinations for rose leaf gloss and their applications. Summary of the Invention

[0006] To address the problems of existing technologies, the purpose of this invention is to provide a genome-wide SNP molecular marker combinatorial array for rose leaf gloss and its application.

[0007] To achieve the aforementioned objective, the present invention employs the following technical solution:

[0008] Firstly, this application provides a genome-wide SNP molecular marker combination for the glossiness of rose leaves.

[0009] Secondly, this application provides a predictive probe for the luster of rose leaves.

[0010] Thirdly, this application provides a predictive chip for the luster of rose leaves.

[0011] Fourthly, this application provides an application of SNP molecular marker combinations, probes, or chips in the prediction of rose leaf gloss.

[0012] Fifthly, this application provides a method for predicting the gloss of rose leaves based on SNP molecular marker combinations.

[0013] Sixthly, this application provides an application of SNP site combinations, probes, chips, or prediction methods in the molecular breeding of roses.

[0014] Seventhly, this application provides a molecular breeding method for roses based on SNP markers.

[0015] The first aspect of this application provides a genome-wide SNP molecular marker combination for rose leaf gloss, which includes 4746 SNP loci distributed on the 14 chromosomes of rose. The specific information of the SNP loci is represented in the form of chromosome number_physical location_allele. The SNP loci contain dominant alleles that are positively and significantly associated with rose leaf gloss. The specific locus information is shown in Table 1 of the specification.

[0016] Furthermore, the SNP loci were determined through genome-wide association analysis of 358 rose resequencing materials, and were screened using multiple software and models.

[0017] The second aspect of this application provides a predictive probe for the gloss of rose leaves. The probe is designed with features of a combination of SNP sites, and its sequence is optimized to have high specificity and high sensitivity, enabling it to accurately capture target SNP sites.

[0018] A third aspect of this application provides a prediction chip for rose leaf gloss. The prediction chip includes probes for detecting the 4746 SNP sites. By detecting the genotype of the SNP sites in the genomic DNA of the rose sample to be tested, and using a pre-constructed whole-genome selection model, the gloss trait of rose leaves can be accurately predicted.

[0019] The fourth aspect of this application provides an application of SNP molecular marker combinations, probes, or chips in the prediction of rose leaf gloss, which involves extracting genomic DNA from rose plants and detecting it using SNP site combinations, probes, or chips.

[0020] The fifth aspect of this application provides a method for predicting the gloss of rose leaves based on SNP molecular marker combinations, comprising the following steps:

[0021] (1) Extract genomic DNA from the rose plants to be tested;

[0022] (2) Construct a library from the genomic DNA;

[0023] (3) Use probes to hybridize and capture DNA fragments in the library to enrich DNA fragments containing target SNP sites;

[0024] (4) Perform high-throughput sequencing on the captured DNA fragments;

[0025] (5) Compare and analyze the sequencing data with the rose reference genome to determine the genotype of the SNP site;

[0026] (6) Input the genotype data of the SNP loci into the whole genome selection model to obtain the prediction results of the glossy trait of the rose leaves to be tested.

[0027] Furthermore, Lasso Regression (Lasso) in the model has the highest prediction accuracy, with an overall prediction accuracy greater than 0.738.

[0028] The sixth aspect of this application provides an application of SNP site combinations, probes, chips, or prediction methods in rose molecular breeding, which is used to predict and screen the leaf gloss traits of breeding materials in an early, accurate, and efficient manner during the rose breeding process, thereby shortening the breeding cycle, improving selection efficiency, and cultivating new rose varieties with excellent leaf gloss traits.

[0029] Furthermore, a genome-wide selection model constructed based on SNP site combinations can predict the leaf gloss of roses with a prediction accuracy greater than 0.738.

[0030] The seventh aspect of this application provides a molecular breeding method for roses based on SNP markers, comprising the following steps:

[0031] (1) Extracting genomic DNA from roses;

[0032] (2) Using microarrays to capture and enrich genomic DNA;

[0033] (3) Perform high-throughput sequencing on the captured and enriched DNA;

[0034] (4) Analyze sequencing data and detect the genotypes of 4746 SNP loci.

[0035] Beneficial effects: This invention has the advantages of high-throughput detection, low cost and shortened breeding cycle, which can significantly improve breeding efficiency, accelerate the cultivation of new rose varieties with good luster, meet the market demand for high-quality roses, and promote the development of the flower industry.

[0036] Compared with the prior art, the present invention has the following advantages:

[0037] (1) The present invention can predict the leaf gloss trait of rose plants by DNA detection during the seed or seedling stage, avoiding the drawback of traditional breeding methods that require waiting for the plants to grow before trait evaluation, greatly shortening the breeding cycle and accelerating the breeding process.

[0038] (2) The present invention can simultaneously perform high-throughput detection of a large number of SNP sites. Compared with the traditional gene-by-gene detection method, the detection efficiency is significantly improved, and germplasm resources with excellent traits can be quickly identified.

[0039] (3) This invention reduces the workload and resource input for screening materials after field planting, thereby lowering the overall cost of breeding. At the same time, liquid-phase breeding chips require relatively fewer raw materials and reagents in probe synthesis and chip fabrication, significantly reducing production costs.

[0040] (4) This invention is based on the specific SNP site combination screened by genome-wide association analysis and evaluated by a variety of genome-wide selection models. Among them, the Lasso Regression (Lasso) model has a prediction accuracy of over 0.738, which provides a scientific and accurate basis for the prediction of the glossy trait of rose leaves.

[0041] (5) This invention helps to quickly cultivate new rose varieties with good luster, meet the market demand for high-quality roses, enrich flower varieties, improve the market competitiveness of the flower industry, and create higher economic value for the flower industry. Attached Figure Description

[0042] To more clearly illustrate the technical solutions in the embodiments of this application, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0043] Figure 1 The whole chromosome marker distribution map of rose leaf luster provided by this invention can be used to screen for heterozygous sensitive markers related to leaf luster, which can be used to quickly identify superior genotypes.

[0044] Figure 2 The allele frequency map of rose leaf gloss provided by this invention reflects the enrichment degree of target alleles during the breeding process.

[0045] Figure 3 The diagram shows the loss rate of luster in rose leaves provided by this invention.

[0046] Figure 4 This is a heterogeneity diagram of rose leaf luster provided by the present invention.

[0047] Figure 5 The image provided by this invention shows the results of whole-genome selection evaluation of rose leaf gloss. By analyzing the distribution pattern of missing sites in the genomic data, it provides a basis for data quality control. Detailed Implementation

[0048] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0049] In this application, the term "and / or" describes the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. A and B can be singular or plural. The character " / " generally indicates that the preceding and following related objects have an "or" relationship.

[0050] In this application, "-one less" means one or more, and "more than" means two or more. "-one less item (item) below" or similar expressions refer to any combination of these items, including any combination of single or multiple items. For example, "-one less item (item) in a, b, or c", or "-one less item (item) in a, b, and c", can all mean: a, b, c, ab (i.e., a and b), ac, bc, or abc, where a, b, and c can be single or multiple.

[0051] It should be understood that in the various embodiments of this application, the sequence number of each process does not imply the order of execution. Some or all steps may be executed in parallel or sequentially. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of this application.

[0052] The terminology used in the embodiments of this application is for the purpose of describing particular embodiments only and is not intended to be limiting of this application. The singular forms “a,” “the,” and “the” used in the embodiments of this application and the appended claims are also intended to include the plural forms unless the context clearly indicates otherwise.

[0053] The weights of the relevant components mentioned in the embodiments of this application can refer not only to the specific content of each component, but also to the proportional relationship between the weights of the components. Therefore, any scaling up or down of the content of the relevant components according to the embodiments of this application is within the scope disclosed in the embodiments of this application. Specifically, the mass described in the embodiments of this application can be a mass unit known in the chemical industry, such as μg, mg, g, or kg.

[0054] The terms "first" and "second" are used for descriptive purposes only, to distinguish objects, such as substances, from one another, and should not be construed as indicating or implying relative importance or implicitly specifying the diameter of the indicated technical features. For example, without departing from the scope of the embodiments of this application, a first XX may also be referred to as a second XX, and similarly, a second XX may also be referred to as a first XX. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of that feature.

[0055] The first aspect of this application provides a genome-wide SNP molecular marker combination for rose leaf gloss, which includes 4746 SNP loci distributed on the 14 chromosomes of the rose.

[0056] The specific information of the SNP loci is represented in the structure of chromosome number_physical location_allele. The SNP loci contain dominant alleles that are positively and significantly associated with the gloss of rose leaves. The specific locus information is shown in Appendix 1 of the instruction manual.

[0057] In some embodiments, the SNP sites were determined by genome-wide association analysis of 358 rose resequencing materials, and were screened using multiple software and models.

[0058] The second aspect of this application provides a predictive probe for rose leaf gloss. The probe is designed with features of a combination of SNP sites, and its sequence is optimized to have high specificity and high sensitivity, enabling it to accurately capture target SNP sites.

[0059] The third aspect of this application provides a prediction chip for rose leaf gloss. The prediction chip includes probes for detecting 4746 SNP sites. By detecting the genotype of SNP sites in the genomic DNA of the rose sample to be tested, and using a pre-constructed whole-genome selection model, the gloss trait of rose leaves can be accurately predicted.

[0060] The fourth aspect of this application provides an application of SNP molecular marker combinations, probes, or chips in the prediction of rose leaf gloss, by extracting genomic DNA from rose plants and using SNP site combinations, probes, or chips for detection.

[0061] The fifth aspect of this application provides a method for predicting the gloss of rose leaves based on SNP molecular marker combinations, including the following steps:

[0062] (1) Extract genomic DNA from the rose plants to be tested;

[0063] (2) Constructing a library of genomic DNA;

[0064] (3) Use probes to hybridize and capture DNA fragments in the library to enrich DNA fragments containing target SNP sites;

[0065] (4) Perform high-throughput sequencing on the captured DNA fragments;

[0066] (5) Compare and analyze the sequencing data with the rose reference genome to determine the genotype of the SNP site;

[0067] (6) Input the genotype data of the SNP loci into the whole genome selection model to obtain the prediction results of the glossy trait of the rose leaves to be tested.

[0068] In some embodiments, Lasso Regression (Lasso) has the highest prediction accuracy in the model, with an overall prediction accuracy greater than 0.738.

[0069] The sixth aspect of this application provides an application of SNP site combinations, probes, chips, or prediction methods in rose molecular breeding, which is used to predict and screen the leaf gloss traits of breeding materials in an early, accurate, and efficient manner during the rose breeding process, thereby shortening the breeding cycle, improving selection efficiency, and cultivating new rose varieties with excellent leaf gloss traits.

[0070] In some embodiments, a genome-wide selection model constructed based on the SNP site combination can predict the leaf gloss of roses with a prediction accuracy greater than 0.738.

[0071] The seventh aspect of this application provides a method for molecular breeding of roses based on SNP markers, comprising the following steps:

[0072] (1) Extracting genomic DNA from roses;

[0073] (2) Using microarrays to capture and enrich genomic DNA;

[0074] (3) Perform high-throughput sequencing on the captured and enriched DNA;

[0075] (4) Analyze the sequencing data and detect the genotypes of the 4746 SNP sites.

[0076] Example 1

[0077] This invention provides a genome-wide SNP molecular marker combination for rose leaf gloss, comprising 4746 SNP loci distributed on the 14 chromosomes of the rose. The specific information of the SNP loci is represented in the structure of chromosome number_physical location_allele. The SNP loci contain dominant alleles that are positively and significantly associated with rose leaf gloss. The specific locus information is shown in Table 1.

[0078] Table 1

[0079] Chr1A_4177240_G / A,Chr1A_4362004_T / C,Chr1A_4362007_A / G,Chr1A_4367292_C / T,Chr1A_6051744_A / G,Chr1A_17592489_T / G,Chr1A_29380175_C / T,Chr1A_30298249_G / A,Chr1A_30298256_A / T,Chr1A_48235277_T / A,Chr1A_56337578_G / A,Chr1A_62120439_T / C,Chr1A_62120770_A / T,Chr1B_2101084_T / A,Chr1B_3088819_T / G,Chr1B_3088822_T / G,Chr1B_3088854_C / G,Chr1B_3088871_T / G,Chr1B_3089102_T / C,Chr1B_3230021_T / G,Chr1B_3230058_A / C,Chr1B_3230103_T / A,Chr1B_3230240_A / G,Chr1B_3230269_C / T,Chr1B_3238581_T / C,Chr1B_3238591_A / G,Chr1B_3819808_G / A,Chr1B_3852540_C / T,Chr1B_3852570_C / T,Chr1B_3852573_C / T,Chr1B_3852575_T / C,Chr1B_3866828_T / C,Chr1B_4627948_A / T,Chr1B_5050992_T / C,Chr1B_5459128_G / T,Chr1B_15336701_G / A,Chr1B_18460288_G / A,Chr1B_18460291_G / A,Chr1B_18460313_G / T,Chr1B_18460365_C / T,Chr1B_18504689_T / C,Chr1B_18505960_T / A,Chr1B_18505997_A / G,Chr1B_18506122_A / G,Chr1B_18506130_T / A,Chr1B_18531815_T / C,Chr1B_18531971_T / C,Chr1B_18532004_A / C,Chr1B_18532023_G / A,Chr1B_18532160_C / A,Chr1B_23509731_A / G,Chr1B_23509740_A / G,Chr1B_24435290_T / A,Chr1B_24435291_C / T,Chr1B_24435397_G / A,Chr1B_24435428_T / C,Chr1B_24435434_A / G,Chr1B_24435444_A / G,Chr1B_24435460_C / T,Chr1B_24435480_C / T,Chr1B_24435487_G / A,Chr1B_24435503_A / G,Chr1B_24435510_A / G,Chr1B_24435533_T / C,Chr1B_24435537_G / C,Chr1B_24435574_C / T,Chr1B_24435595_G / A,Chr1B_24435597_G / T,Chr1B_24435610_C / T,Chr1B_24435613_T / C,Chr1B_24435641_G / C,Chr1B_29385226_G / A,Chr1B_30101113_G / T,Chr1B_30101294_G / T,Chr1B_30101295_T / A,Chr1B_30101486_A / T,Chr1B_30101518_C / T,Chr1B_30101657_C / A,Chr1B_30101854_C / T,Chr1B_30101918_T / C,Chr1B_36630691_G / A,Chr1B_38871804_T / C,Chr1B_38871817_T / C,Chr1B_38871880_A / G,Chr1B_38871887_A / G,Chr1B_39736548_T / G,Chr1B_39736549_C / G,Chr1B_39736562_A / G,Chr1B_39858626_T / C,Chr1B_40024647_T / C,Chr2A_28102376_T / G,Chr2A_28102446_G / A,Chr2A_28102551_C / T,Chr2A_28102695_C / T,Chr2A_28102765_T / C,Chr2A_37392181_G / A,Chr2A_37392194_C / G,Chr2A_38981205_A / G,Chr2A_38981219_C / T,Chr2A_38981241_G / T,Chr2A_38981291_A / G,Chr2A_38981295_A / G,Chr2A_38981332_A / C,Chr2A_38981336_G / T,Chr2A_40516032_G / T,Chr2A_45329538_A / T,Chr2A_45329582_T / C,Chr2A_45329633_T / C,Chr2A_45329675_A / T,Chr2A_45329842_C / T,Chr2A_45329897_A / G,Chr2A_87558725_G / A,Chr2A_87558748_C / T,Chr2B_60210_T / C,Chr2B_758062_C / T,Chr2B_758095_T / C,Chr2B_2018880_A / G,Chr2B_2920634_C / G,Chr2B_3795921_A / G,Chr2B_9261699_T / G,Chr2B_9261700_C / A,Chr2B_10664605_T / C,Chr2B_67828086_G / T,Chr2B_68177422_C / A,Chr2B_78842909_A / G,Chr2B_78842913_G / T,Chr2B_78842946_A / G,Chr2B_81845109_G / A,Chr3A_25969404_G / A,Chr3A_45960616_T / C,Chr3A_47667404_T / A,Chr3A_47667410_A / G,Chr3A_47667438_G / A,Chr3A_47667447_G / T,Chr3A_47667463_G / T,Chr3A_47667500_G / A,Chr3B_43466765_C / G,Chr4A_16799265_C / T,Chr4A_16799269_G / A,Chr4A_16799273_C / T,Chr4A_22654383_G / A,Chr4A_23270767_A / G,Chr4A_24214686_C / T,Chr4A_25738594_T / C,Chr4A_25738624_C / T,Chr4A_25820814_A / G,Chr4A_25820845_T / C,Chr4A_33404965_G / A,Chr4A_36381444_A / C,Chr4A_38106180_T / C,Chr4A_38106181_T / C,Chr4A_38106199_A / G,Chr4A_38665310_T / A,Chr4A_41363570_T / G,Chr4A_41363575_T / C,Chr4A_41363612_G / A,Chr4A_41502240_G / A,Chr4A_41502242_A / G,Chr4A_41602735_A / G,Chr4A_41602740_A / G,Chr4A_41602744_T / C,Chr4A_41602750_T / C,Chr4A_41602792_G / T,Chr4A_41602805_T / C,Chr4A_41605371_G / T,Chr4A_41605382_T / C,Chr4A_41605395_A / C,Chr4A_41605398_G / A,Chr4A_41605413_A / G,Chr4A_41615048_T / C,Chr4A_41615272_C / T,Chr4A_41665685_C / T,Chr4A_41665802_C / G,Chr4A_41665808_G / C,Chr4A_41665809_C / A,Chr4A_41665850_T / C,Chr4A_41665865_A / G,Chr4A_41665882_A / G,Chr4A_41665910_T / C,Chr4A_41670154_G / C,Chr4A_41705705_C / G,Chr4A_41716235_T / C,Chr4A_41716247_A / G,Chr4A_41733996_G / A,Chr4A_41896439_C / T,Chr4A_41896689_G / A,Chr4A_41961360_C / T,Chr4A_41970411_T / C,Chr4A_41970430_T / A,Chr4A_41970525_C / T,Chr4A_41970602_C / T,Chr4A_41970613_T / C,Chr4A_41970670_G / T,Chr4A_41970689_A / G,Chr4A_42053188_G / A,Chr4A_42399033_A / C,Chr4A_42399037_C / A,Chr4A_43114687_G / A,Chr4A_43114794_A / G,Chr4A_43114809_G / A,Chr4A_43114810_A / C,Chr4A_44014317_A / G,Chr4A_44077235_T / C,Chr4A_44077254_T / C,Chr4A_44077266_T / C,Chr4A_44077277_T / C,Chr4A_44077362_A / G,Chr4A_44077364_T / C,Chr4A_44077375_A / G,Chr4A_44077386_C / T,Chr4A_44818026_G / A,Chr4A_44928677_G / A,Chr4A_45838104_C / A,Chr4A_46488901_G / C,Chr4A_46494193_G / A,Chr4A_46495103_G / T,Chr4A_46718646_C / T,Chr4A_46792817_C / T,Chr4A_46855917_A / T,Chr4A_47077157_T / C,Chr4A_47077190_C / A,Chr4A_47077195_G / A,Chr4A_47077215_A / G,Chr4A_47077258_C / T,Chr4A_47077264_A / G,Chr4A_47077286_G / T,Chr4A_47077314_A / C,Chr4A_47077323_T / G,Chr4A_47175491_T / G,Chr4A_47175608_G / T,Chr4A_47234674_G / A,Chr4A_47248096_C / A,Chr4A_47248196_C / G,Chr4A_47248575_A / G,Chr4A_47304912_C / T,Chr4A_47667635_T / G,Chr4A_47780106_T / C,Chr4A_48186464_G / A,Chr4A_48219468_A / C,Chr4A_48268235_A / G,Chr4A_48303736_G / A,Chr4A_48303955_T / C,Chr4A_48303967_A / C,Chr4A_48371826_A / C,Chr4A_48371937_A / G,Chr4A_48373190_T / C,Chr4A_48375241_T / C,Chr4A_48559990_A / C,Chr4A_48559993_A / T,Chr4A_48560016_G / A,Chr4A_48560039_A / G,Chr4A_48560059_G / C,Chr4A_48560068_A / C,Chr4A_48560072_G / C,Chr4A_49235907_A / G,Chr4A_49243490_A / G,Chr4A_49243511_G / A,Chr4A_49347843_C / T,Chr4A_49347852_T / C,Chr4A_49347865_A / T,Chr4A_49429506_A / G,Chr4A_49429517_G / A,Chr4A_49429520_A / G,Chr4A_49429554_T / A,Chr4A_49429561_G / A,Chr4A_49429619_A / G,Chr4A_49429620_A / T,Chr4A_49429625_T / A,Chr4A_49429634_T / C,Chr4A_49429699_A / G,Chr4A_49429707_C / G,Chr4A_49447409_A / G,Chr4A_49447414_T / C,Chr4A_49447445_G / A,Chr4A_49454839_T / C,Chr4A_49454884_A / G,Chr4A_49454890_C / T,Chr4A_49484421_T / C,Chr4A_49484442_A / G,Chr4A_49484452_C / T,Chr4A_49502302_G / A,Chr4A_49569422_G / C,Chr4A_49569424_C / T,Chr4A_49578129_C / T,Chr4A_49578138_A / C,Chr4A_49578145_C / T,Chr4A_49578147_A / G,Chr4A_49578152_C / T,Chr4A_49578185_T / A,Chr4A_49578216_C / A,Chr4A_49578318_T / G,Chr4A_49578344_C / T,Chr4A_49578405_T / G,Chr4A_49578434_A / C,Chr4A_49578491_A / G,Chr4A_49578575_A / G,Chr4A_49578596_G / A,Chr4A_49628201_G / C,Chr4A_49628210_T / C,Chr4A_49642707_A / G,Chr4A_49642718_C / T,Chr4A_49642774_C / T,Chr4A_49642779_C / T,Chr4A_49642784_A / G,Chr4A_49642799_A / G,Chr4A_49642819_C / T,Chr4A_49642826_T / C,Chr4A_49642829_T / C,Chr4A_49642836_T / C,Chr4A_49642850_A / G,Chr4A_49642932_T / C,Chr4A_49642952_T / C,Chr4A_49642993_T / C,Chr4A_49642995_T / C,Chr4A_49642999_C / A,Chr4A_49643003_T / C,Chr4A_49643007_T / C,Chr4A_49643012_A / G,Chr4A_49643043_C / G,Chr4A_49643049_A / G,Chr4A_49643058_T / C,Chr4A_49643094_A / T,Chr4A_49643145_A / G,Chr4A_49643152_T / C,Chr4A_49643167_G / A,Chr4A_49643175_G / A,Chr4A_49643217_A / G,Chr4A_49643218_A / G,Chr4A_49643235_A / T,Chr4A_49643241_A / C,Chr4A_49643245_C / A,Chr4A_49643260_G / A,Chr4A_49643268_C / T,Chr4A_49672327_G / A,Chr4A_49672350_C / A,Chr4A_49672373_C / T,Chr4A_49672449_C / T,Chr4A_49672575_A / G,Chr4A_49672645_T / C,Chr4A_49672665_A / G,Chr4A_49672670_G / A,Chr4A_49672694_T / C,Chr4A_49672766_T / G,Chr4A_49672776_T / C,Chr4A_49682925_T / G,Chr4A_49689214_G / C,Chr4A_49695849_G / A,Chr4A_49794182_T / C,Chr4A_49794185_G / A,Chr4A_49794199_T / A,Chr4A_49794224_G / A,Chr4A_49794228_A / T,Chr4A_49794242_G / C,Chr4A_49794245_T / G,Chr4A_49794255_G / A,Chr4A_49794265_C / G,Chr4A_49799034_T / C,Chr4A_49799047_C / T,Chr4A_49799060_A / G,Chr4A_49799075_T / C,Chr4A_49799090_G / A,Chr4A_49799094_T / C,Chr4A_49799095_G / A,Chr4A_49799135_G / A,Chr4A_49799143_G / T,Chr4A_49829967_T / C,Chr4A_49830008_A / G,Chr4A_49830042_G / A,Chr4A_49830099_A / G,Chr4A_49838480_G / A,Chr4A_49838502_G / C,Chr4A_49838503_T / C,Chr4A_49838504_G / C,Chr4A_49838618_T / A,Chr4A_49838661_C / T,Chr4A_49839490_T / A,Chr4A_49839524_A / G,Chr4A_49839550_A / G,Chr4A_49839578_T / C,Chr4A_49839580_G / C,Chr4A_49839598_A / G,Chr4A_49839613_G / A,Chr4A_49839627_C / A,Chr4A_49839738_C / A,Chr4A_49839792_T / G,Chr4A_49839804_A / G,Chr4A_49839815_A / C,Chr4A_49839823_A / T,Chr4A_49843475_A / G,Chr4A_49843531_A / G,Chr4A_49851579_C / T,Chr4A_49851587_C / T,Chr4A_49852147_G / T,Chr4A_49852249_G / T,Chr4A_49852289_G / C,Chr4A_49852492_T / A,Chr4A_49852693_A / G,Chr4A_49852862_C / T,Chr4A_49853000_G / A,Chr4A_49853214_G / A,Chr4A_49853466_G / A,Chr4A_49983204_T / G,Chr4A_49983210_G / C,Chr4A_49984014_T / C,Chr4A_49984015_A / T,Chr4A_49991804_T / C,Chr4A_49991822_A / G,Chr4A_50013560_T / C,Chr4A_50035390_C / G,Chr4A_50035449_G / T,Chr4A_50035456_T / C,Chr4A_50035533_T / G,Chr4A_50035534_A / G,Chr4A_50035563_G / A,Chr4A_50035570_T / G,Chr4A_50035580_C / A,Chr4A_50035610_T / A,Chr4A_50035612_G / A,Chr4A_50035628_A / C,Chr4A_50035673_C / A,Chr4A_50035675_T / A,Chr4A_50041209_C / T,Chr4A_50041213_A / T,Chr4A_50041222_G / A,Chr4A_50041226_G / A,Chr4A_50041286_T / C,Chr4A_50041299_A / G,Chr4A_50041306_T / G,Chr4A_50041444_T / A,Chr4A_50041545_T / C,Chr4A_50041605_G / T,Chr4A_50041632_T / G,Chr4A_50041670_T / C,Chr4A_50041672_C / A,Chr4A_50041699_T / C,Chr4A_50041725_T / G,Chr4A_50041779_A / C,Chr4A_50041788_C / T,Chr4A_50041813_T / A,Chr4A_50041814_T / A,Chr4A_50041863_C / A,Chr4A_50041880_A / G,Chr4A_50041883_C / T,Chr4A_50041938_A / C,Chr4A_50041940_C / T,Chr4A_50041942_G / A,Chr4A_50042022_A / G,Chr4A_50042093_A / G,Chr4A_50042119_A / C,Chr4A_50042120_T / C,Chr4A_50042146_T / A,Chr4A_50042164_A / G,Chr4A_50042216_T / A,Chr4A_50042218_G / A,Chr4A_50042239_G / A,Chr4A_50042248_T / A,Chr4A_50042249_G / T,Chr4A_50042252_A / G,Chr4A_50042255_A / T,Chr4A_50157108_G / A,Chr4A_50157118_T / A,Chr4A_50157121_A / G,Chr4A_50157150_G / C,Chr4A_50157163_T / C,Chr4A_50157166_C / T,Chr4A_50157188_C / T,Chr4A_50189337_G / T,Chr4A_50209558_T / C,Chr4A_50209571_T / C,Chr4A_50209641_C / A,Chr4A_50209884_C / T,Chr4A_50209941_T / A,Chr4A_50209973_C / G,Chr4A_50209985_G / T,Chr4A_50210102_G / T,Chr4A_50210158_C / G,Chr4A_50210185_G / A,Chr4A_50210188_A / C,Chr4A_50210201_A / C,Chr4A_50211069_G / C,Chr4A_50211132_A / C,Chr4A_50211235_G / A,Chr4A_50211260_T / C,Chr4A_50211270_G / T,Chr4A_50211313_T / G,Chr4A_50211342_T / C,Chr4A_50211364_T / C,Chr4A_50211419_T / A,Chr4A_50214834_T / C,Chr4A_50214906_T / C,Chr4A_50214915_T / A,Chr4A_50214926_C / A,Chr4A_50214927_G / A,Chr4A_50214968_T / G,Chr4A_50214977_A / G,Chr4A_50215042_G / A,Chr4A_50215058_G / C,Chr4A_50215074_T / C,Chr4A_50215075_C / T,Chr4A_50215300_C / T,Chr4A_50215329_A / T,Chr4A_50215351_T / C,Chr4A_50215383_T / G,Chr4A_50215390_G / A,Chr4A_50215402_A / T,Chr4A_50236137_C / T,Chr4A_50236149_A / G,Chr4A_50236206_C / T,Chr4A_50236207_G / A,Chr4A_50236243_G / C,Chr4A_50236317_C / T,Chr4A_50237112_T / C,Chr4A_50237136_A / T,Chr4A_50306972_G / T,Chr4A_50307050_A / G,Chr4A_50307064_T / C,Chr4A_50307065_T / C,Chr4A_50307100_G / A,Chr4A_50307116_C / G,Chr4A_50307169_C / T,Chr4A_50307225_T / C,Chr4A_50307235_T / C,Chr4A_50307239_G / T,Chr4A_50307266_G / A,Chr4A_50307270_C / A,Chr4A_50307434_C / A,Chr4A_50307440_A / G,Chr4A_50307541_T / C,Chr4A_50307689_C / T,Chr4A_50307744_A / T,Chr4A_50307796_C / T,Chr4A_50308004_A / C,Chr4A_50308017_G / T,Chr4A_50308069_A / G,Chr4A_50308071_C / T,Chr4A_50308091_A / T,Chr4A_50308145_G / A,Chr4A_50308238_C / G,Chr4A_50308286_C / A,Chr4A_50308522_C / G,Chr4A_50313977_T / C,Chr4A_50313981_A / G,Chr4A_50314011_C / T,Chr4A_50314015_A / G,Chr4A_50322196_G / A,Chr4A_50336237_T / C,Chr4A_50336259_T / C,Chr4A_50336270_C / T,Chr4A_50336277_C / T,Chr4A_50336285_A / G,Chr4A_50336298_G / T,Chr4A_50336300_C / T,Chr4A_50337198_G / A,Chr4A_50360587_G / C,Chr4A_50360590_G / A,Chr4A_50360623_A / G,Chr4A_50360665_G / A,Chr4A_50360674_C / A,Chr4A_50360678_A / G,Chr4A_50360682_T / A,Chr4A_50360683_G / A,Chr4A_50412988_C / A,Chr4A_50434008_C / G,Chr4A_50457521_T / G,Chr4A_50457525_G / A,Chr4A_50457533_T / C,Chr4A_50457542_T / G,Chr4A_50499178_G / A,Chr4A_50499269_T / A,Chr4A_50499288_A / G,Chr4A_50499351_T / C,Chr4A_50499358_C / T,Chr4A_50499374_A / G,Chr4A_50499446_T / G,Chr4A_50499471_A / G,Chr4A_50507279_C / G,Chr4A_50507289_T / G,Chr4A_50507294_T / C,Chr4A_50507358_C / T,Chr4A_50516822_T / C,Chr4A_50538134_A / G,Chr4A_50538162_T / C,Chr4A_50538169_G / C,Chr4A_50538229_A / G,Chr4A_50538230_A / C,Chr4A_50538263_C / T,Chr4A_50538271_G / T,Chr4A_50538289_C / T,Chr4A_50538304_T / C,Chr4A_50538369_G / T,Chr4A_50538427_G / A,Chr4A_50538450_A / T,Chr4A_50538481_G / A,Chr4A_50538490_T / C,Chr4A_50538534_C / A,Chr4A_50538565_A / G,Chr4A_50556732_A / G,Chr4A_50558101_C / T,Chr4A_50558125_T / C,Chr4A_50558146_G / A,Chr4A_50558197_G / C,Chr4A_50558213_A / G,Chr4A_50558353_T / A,Chr4A_50558383_C / T,Chr4A_50558447_T / G,Chr4A_50560024_G / T,Chr4A_50560044_T / A,Chr4A_50560066_T / C,Chr4A_50739961_G / C,Chr4A_50740282_T / G,Chr4A_50740308_A / T,Chr4A_50740354_C / G,Chr4A_50740383_C / T,Chr4A_50740390_C / T,Chr4A_50740398_G / T,Chr4A_50740463_A / T,Chr4A_50740471_T / A,Chr4A_50740518_G / T,Chr4A_50740750_C / G,Chr4A_50741709_T / A,Chr4A_50750821_C / T,Chr4A_50750835_G / T,Chr4A_50750951_G / A,Chr4A_50750953_G / A,Chr4A_50750971_G / A,Chr4A_50750976_A / G,Chr4A_50751907_G / A,Chr4A_50752290_C / T,Chr4A_50754236_T / C,Chr4A_50754285_T / C,Chr4A_50754303_A / G,Chr4A_50755684_T / A,Chr4A_50755686_T / G,Chr4A_50755710_C / A,Chr4A_50755712_T / A,Chr4A_50755757_T / C,Chr4A_50794048_C / T,Chr4A_50824197_C / A,Chr4A_50824201_T / G,Chr4A_50824352_G / A,Chr4A_50824360_T / C,Chr4A_50824367_C / T,Chr4A_50869194_C / A,Chr4A_50869207_G / T,Chr4A_50869235_A / T,Chr4A_50869370_G / A,Chr4A_50869431_G / A,Chr4A_50869546_C / T,Chr4A_50869552_A / G,Chr4A_50869570_C / T,Chr4A_50869596_C / T,Chr4A_50882807_C / T,Chr4A_50882825_C / T,Chr4A_50882832_C / T,Chr4A_50882852_A / G,Chr4A_50882863_T / C,Chr4A_50882877_G / A,Chr4A_50883409_G / A,Chr4A_50883499_G / A,Chr4A_50883608_C / T,Chr4A_50883616_A / G,Chr4A_50883619_A / G,Chr4A_50883625_C / T,Chr4A_50883629_C / G,Chr4A_50883632_A / C,Chr4A_50982944_T / C,Chr4A_50982948_G / A,Chr4A_50982976_T / A,Chr4A_50983023_T / A,Chr4A_50985029_G / T,Chr4A_50985036_A / G,Chr4A_50985049_T / C,Chr4A_51018934_A / C,Chr4A_51035842_G / C,Chr4A_51042512_G / A,Chr4A_58729998_G / A,Chr4A_59491925_C / T,Chr4A_59491953_C / T,Chr4A_59491954_C / T,Chr4A_59492028_G / C,Chr4A_59653607_G / A,Chr4A_59993361_T / C,Chr4A_60121460_G / C,Chr4A_60137705_C / T,Chr4A_60137733_C / A,Chr4A_60137788_C / T,Chr4A_60137808_T / C,Chr4A_60137826_G / A,Chr4A_60137889_G / A,Chr4A_60138222_G / A,Chr4A_60138241_G / A,Chr4A_60138242_T / C,Chr4A_60138245_C / T,Chr4A_60138301_C / A,Chr4A_60138712_C / G,Chr4A_60144745_T / G,Chr4A_60144813_G / T,Chr4A_60170233_T / C,Chr4A_60170270_T / C,Chr4A_60170278_A / G,Chr4A_60170285_A / G,Chr4A_60170302_G / A,Chr4A_60170318_T / C,Chr4A_60170354_C / T,Chr4A_60177164_T / C,Chr4A_60177248_T / C,Chr4A_60177325_T / A,Chr4A_60177349_T / A,Chr4A_60177465_T / C,Chr4A_60177622_T / C,Chr4A_60177680_G / A,Chr4A_60178032_G / T,Chr4A_60178039_C / T,Chr4A_60178229_A / T,Chr4A_60178245_A / G,Chr4A_60178319_G / C,Chr4A_60178321_G / A,Chr4A_60178399_C / T,Chr4A_60178412_T / C,Chr4A_60178478_C / T,Chr4A_60178500_T / G,Chr4A_60178539_A / G,Chr4A_60178540_T / C,Chr4A_60181578_A / T,Chr4A_60181581_C / A,Chr4A_60181624_C / T,Chr4A_60181645_G / C,Chr4A_60181650_C / G,Chr4A_60181654_G / A,Chr4A_60181664_C / T,Chr4A_60181668_C / T,Chr4A_60181677_G / C,Chr4A_60181680_T / G,Chr4A_60193281_G / A,Chr4A_60205724_A / G,Chr4A_60205769_A / G,Chr4A_60206631_C / G,Chr4A_60234649_A / G,Chr4A_60234684_G / A,Chr4A_60236392_T / G,Chr4A_60237157_T / G,Chr4A_60237392_T / C,Chr4A_60243973_G / A,Chr4A_60246888_T / G,Chr4A_60246892_C / T,Chr4A_60246966_A / G,Chr4A_60246979_T / C,Chr4A_60246980_G / A,Chr4A_60246995_C / T,Chr4A_60247004_A / G,Chr4A_60247017_A / G,Chr4A_60247054_G / T,Chr4A_60247071_G / A,Chr4A_60247072_T / A,Chr4A_60247139_A / G,Chr4A_60247234_T / C,Chr4A_60247263_G / A,Chr4A_60247288_T / C,Chr4A_60247291_T / A,Chr4A_60357226_A / G,Chr4A_60357682_A / T,Chr4A_60357688_C / T,Chr4A_60357745_A / G,Chr4A_60357763_G / A,Chr4A_60357825_G / A,Chr4A_60357826_C / T,Chr4A_60358078_A / C,Chr4A_60358833_G / A,Chr4A_60358853_T / G,Chr4A_60358857_C / A,Chr4A_60358954_G / T,Chr4A_60358987_C / T,Chr4A_60358990_T / C,Chr4A_60359002_G / A,Chr4A_60359006_T / A,Chr4A_60359027_G / C,Chr4A_60398183_A / G,Chr4A_60420187_A / C,Chr4A_60420190_A / G,Chr4A_60441600_A / C,Chr4A_60464818_G / C,Chr4A_60464819_A / G,Chr4A_60579808_T / G,Chr4A_60622548_A / T,Chr4A_60629101_A / C,Chr4A_60629133_G / A,Chr4A_60632485_T / C,Chr4A_60632916_T / C,Chr4A_60632952_A / G,Chr4A_60654680_T / C,Chr4A_60654689_C / T,Chr4A_60654698_G / T,Chr4A_60654728_T / G,Chr4A_60654733_T / A,Chr4A_60690227_T / C,Chr4A_60690232_A / T,Chr4A_60690311_G / T,Chr4A_60753648_C / G,Chr4A_60753661_G / A,Chr4A_60753666_G / T,Chr4A_60753682_G / A,Chr4A_60753918_A / T,Chr4A_60753937_T / C,Chr4A_60754004_T / C,Chr4A_60754008_A / G,Chr4A_60754019_C / T,Chr4A_60920837_C / T,Chr4A_61027323_T / C,Chr4A_61206276_C / T,Chr4A_61206278_T / C,Chr4A_64559223_T / C,Chr4A_64559259_C / A,Chr4A_64559271_G / A,Chr4A_64559280_G / A,Chr4A_64559289_C / T,Chr4A_64559311_C / A,Chr4A_64559325_A / C,Chr4A_64559329_C / A,Chr4A_64559336_C / A,Chr4A_64559354_C / A,Chr4A_64559379_C / T,Chr4A_64883992_A / G,Chr4B_209744_C / T,Chr4B_10043272_G / A,Chr4B_18152744_A / G,Chr4B_18824514_T / C,Chr4B_18824573_T / C,Chr4B_25004988_T / G,Chr4B_25005037_G / C,Chr4B_25005064_G / T,Chr4B_25005084_A / G,Chr4B_25005146_G / T,Chr4B_25005181_A / C,Chr4B_25005262_A / T,Chr4B_25005343_T / A,Chr4B_25005361_C / T,Chr4B_25005378_T / C,Chr4B_25005399_A / T,Chr4B_28112648_A / G,Chr4B_28112657_G / A,Chr4B_28112705_G / T,Chr4B_28112742_A / C,Chr4B_28112762_C / G,Chr4B_31656628_C / G,Chr4B_31972136_A / G,Chr4B_31978987_G / A,Chr4B_31978993_T / G,Chr4B_32113470_C / A,Chr4B_32202009_C / T,Chr4B_32562236_A / G,Chr4B_32605260_A / G,Chr4B_32749368_A / G,Chr4B_32749382_T / A,Chr4B_32759009_G / A,Chr4B_32759018_A / T,Chr4B_32759038_C / G,Chr4B_32759187_A / C,Chr4B_32759189_G / A,Chr4B_32761141_A / G,Chr4B_32761201_T / C,Chr4B_32763425_A / G,Chr4B_32763953_G / A,Chr4B_32764389_G / A,Chr4B_32764466_T / C,Chr4B_32944337_T / C,Chr4B_32944354_T / C,Chr4B_33043180_T / C,Chr4B_33221252_A / T,Chr4B_33221616_T / C,Chr4B_33228267_T / C,Chr4B_33228295_G / A,Chr4B_33228310_A / G,Chr4B_33228313_C / T,Chr4B_33228350_G / T,Chr4B_33228354_A / G,Chr4B_33229873_T / C,Chr4B_33229899_C / T,Chr4B_33229909_T / G,Chr4B_33230032_C / G,Chr4B_33230107_T / A,Chr4B_33230126_A / C,Chr4B_33231138_T / G,Chr4B_33231169_T / A,Chr4B_33231176_A / G,Chr4B_33231181_T / C,Chr4B_33231219_T / C,Chr4B_33231230_C / A,Chr4B_33231319_A / G,Chr4B_33231405_C / G,Chr4B_33231422_G / A,Chr4B_33231573_A / G,Chr4B_33231577_G / A,Chr4B_33231587_T / C,Chr4B_33231597_T / A,Chr4B_33231608_A / G,Chr4B_33233360_G / A,Chr4B_33233376_T / G,Chr4B_33233380_C / T,Chr4B_33233393_T / G,Chr4B_33233439_G / T,Chr4B_33233470_T / A,Chr4B_33233476_A / T,Chr4B_33305033_T / C,Chr4B_33656150_G / A,Chr4B_33656152_A / C,Chr4B_33656280_C / T,Chr4B_33656282_T / C,Chr4B_33656351_C / G,Chr4B_33656365_T / C,Chr4B_33656423_T / C,Chr4B_33656443_A / T,Chr4B_33656456_G / A,Chr4B_33888941_G / A,Chr4B_35126805_C / A,Chr4B_35248626_C / T,Chr4B_35482486_A / G,Chr4B_36787926_A / G,Chr4B_36817406_C / T,Chr4B_36817597_G / A,Chr4B_36820943_T / C,Chr4B_36953457_T / C,Chr4B_36953467_C / G,Chr4B_36953522_A / G,Chr4B_36953545_A / G,Chr4B_36974973_T / C,Chr4B_36974977_T / C,Chr4B_36975140_T / C,Chr4B_36975211_T / C,Chr4B_36975364_A / G,Chr4B_36975409_A / T,Chr4B_37088148_C / G,Chr4B_37088157_G / T,Chr4B_37088165_C / T,Chr4B_37088166_C / T,Chr4B_37088208_A / G,Chr4B_37088210_T / C,Chr4B_37088292_G / A,Chr4B_37088354_A / C,Chr4B_37088393_A / C,Chr4B_37088394_G / A,Chr4B_37088614_T / G,Chr4B_37088633_A / G,Chr4B_37088683_T / C,Chr4B_37088858_T / G,Chr4B_37088859_T / C,Chr4B_37088863_T / A,Chr4B_37088971_G / A,Chr4B_37088980_G / C,Chr4B_37089267_G / A,Chr4B_37089314_G / A,Chr4B_37089549_G / C,Chr4B_37099940_G / A,Chr4B_37474731_A / G,Chr4B_37474732_A / G,Chr4B_37704658_A / C,Chr4B_37711889_A / G,Chr4B_37802549_A / T,Chr4B_37802558_T / C,Chr4B_37853788_A / T,Chr4B_37854161_A / T,Chr4B_37854626_G / C,Chr4B_37854649_A / G,Chr4B_37854652_G / A,Chr4B_37854658_A / G,Chr4B_37854661_A / G,Chr4B_37854702_T / C,Chr4B_37855572_T / G,Chr4B_37855584_A / G,Chr4B_37855628_C / T,Chr4B_37855665_C / A,Chr4B_37855781_T / C,Chr4B_37855797_A / G,Chr4B_37855975_C / A,Chr4B_37856082_A / G,Chr4B_37870926_T / G,Chr4B_37870974_C / T,Chr4B_37871151_G / A,Chr4B_37871255_C / T,Chr4B_37871263_G / A,Chr4B_37871281_G / T,Chr4B_37871338_G / A,Chr4B_37871528_A / T,Chr4B_37871850_T / G,Chr4B_37871878_A / G,Chr4B_37872044_T / C,Chr4B_37872065_T / C,Chr4B_37872091_T / C,Chr4B_37872096_C / T,Chr4B_37872097_A / G,Chr4B_37872290_T / C,Chr4B_37872303_T / A,Chr4B_37872306_T / A,Chr4B_37873127_C / T,Chr4B_37873185_G / A,Chr4B_38037671_A / G,Chr4B_38037672_C / G,Chr4B_38037694_C / G,Chr4B_38037731_G / C,Chr4B_38038247_A / G,Chr4B_38065889_G / C,Chr4B_38065920_G / C,Chr4B_38065938_C / A,Chr4B_38065946_T / C,Chr4B_38065949_A / G,Chr4B_38163758_C / T,Chr4B_38163760_T / C,Chr4B_38163761_G / T,Chr4B_38294626_A / T,Chr4B_38294628_C / T,Chr4B_38294630_G / T,Chr4B_38294637_G / A,Chr4B_38294663_G / C,Chr4B_38294675_T / C,Chr4B_38294687_T / C,Chr4B_38294694_A / G,Chr4B_38294711_A / G,Chr4B_38294731_C / T,Chr4B_38294737_T / C,Chr4B_38463515_T / C,Chr4B_38464756_G / A,Chr4B_38464792_G / A,Chr4B_38464793_G / C,Chr4B_38464861_C / G,Chr4B_38464862_G / A,Chr4B_38464868_A / G,Chr4B_38466741_G / A,Chr4B_38466821_C / T,Chr4B_38466889_T / C,Chr4B_38466890_C / T,Chr4B_38466893_A / T,Chr4B_38466924_G / A,Chr4B_38466945_G / A,Chr4B_38526675_C / T,Chr4B_38528191_A / T,Chr4B_38528213_G / A,Chr4B_38528298_C / T,Chr4B_38528379_C / A,Chr4B_38528382_A / G,Chr4B_38528402_G / T,Chr4B_38536382_C / T,Chr4B_38536385_C / T,Chr4B_38536388_T / C,Chr4B_38536390_G / T,Chr4B_38536719_G / A,Chr4B_38536751_A / C,Chr4B_38543816_T / C,Chr4B_38583283_C / T,Chr4B_38583312_G / A,Chr4B_38588420_A / C,Chr4B_38588537_G / A,Chr4B_38588558_C / T,Chr4B_38588599_C / T,Chr4B_38588611_G / A,Chr4B_38588626_G / A,Chr4B_38588656_T / C,Chr4B_38588661_C / T,Chr4B_38588773_T / C,Chr4B_38730539_G / A,Chr4B_38730620_T / C,Chr4B_38739759_T / G,Chr4B_38739780_T / C,Chr4B_38739782_T / C,Chr4B_38739946_T / C,Chr4B_38739951_T / G,Chr4B_38739958_C / A,Chr4B_38739967_G / C,Chr4B_38740124_G / A,Chr4B_38740346_C / T,Chr4B_38740429_A / C,Chr4B_38740868_C / A,Chr4B_38740902_A / C,Chr4B_38755292_A / G,Chr4B_38755617_T / C,Chr4B_38776805_G / A,Chr4B_38776847_G / T,Chr4B_38915442_A / G,Chr4B_38915652_C / A,Chr4B_38915653_T / G,Chr4B_38915677_T / C,Chr4B_38916301_T / A,Chr4B_38916571_A / G,Chr4B_38916651_A / G,Chr4B_38916657_A / T,Chr4B_38917390_G / A,Chr4B_38917416_C / T,Chr4B_39135380_T / C,Chr4B_39135382_G / A,Chr4B_39135393_A / C,Chr4B_39135525_G / A,Chr4B_39135532_T / A,Chr4B_39135694_A / G,Chr4B_39281217_C / G,Chr4B_39281219_T / C,Chr4B_39281255_G / T,Chr4B_39281272_A / G,Chr4B_39281277_C / G,Chr4B_39363123_T / A,Chr4B_39368979_T / C,Chr4B_39369256_G / T,Chr4B_39369274_A / T,Chr4B_39369399_C / T,Chr4B_39369632_T / C,Chr4B_39369644_T / G,Chr4B_39397458_C / T,Chr4B_39397466_G / T,Chr4B_39404764_A / T,Chr4B_39404766_C / G,Chr4B_39404980_A / C,Chr4B_39404994_C / T,Chr4B_39405003_T / G,Chr4B_39405034_G / C,Chr4B_39441886_G / A,Chr4B_39441952_C / T,Chr4B_39442034_C / G,Chr4B_39442118_A / G,Chr4B_39442127_G / T,Chr4B_39442254_G / A,Chr4B_39503029_T / A,Chr4B_39503049_G / T,Chr4B_39503056_G / A,Chr4B_39503162_T / C,Chr4B_39503236_G / C,Chr4B_39503246_C / A,Chr4B_39503247_G / A,Chr4B_39503260_A / G,Chr4B_39503269_A / T,Chr4B_39503290_T / G,Chr4B_39503313_T / A,Chr4B_39503322_G / A,Chr4B_39503356_T / G,Chr4B_39503363_T / A,Chr4B_39503387_T / C,Chr4B_39503410_C / T,Chr4B_39503412_A / T,Chr4B_39503418_C / A,Chr4B_39503447_G / A,Chr4B_39503457_A / G,Chr4B_39503557_A / G,Chr4B_39503590_C / G,Chr4B_39503591_A / G,Chr4B_39503640_G / T,Chr4B_39503659_A / C,Chr4B_39503674_C / T,Chr4B_39503705_C / T,Chr4B_39634405_G / A,Chr4B_39634461_A / G,Chr4B_39637581_G / C,Chr4B_39641117_C / T,Chr4B_39662857_G / A,Chr4B_39662879_G / C,Chr4B_39662980_C / T,Chr4B_39663040_A / G,Chr4B_39663706_C / A,Chr4B_39663748_T / A,Chr4B_39663760_A / T,Chr4B_39663792_C / T,Chr4B_39663795_C / A,Chr4B_39663799_T / C,Chr4B_39663918_A / G,Chr4B_39663924_T / C,Chr4B_39664008_G / A,Chr4B_39664009_C / A,Chr4B_39664024_A / C,Chr4B_39664046_A / G,Chr4B_39664064_C / T,Chr4B_39664090_T / C,Chr4B_39664097_T / C,Chr4B_39664129_C / T,Chr4B_39664134_T / C,Chr4B_39664156_G / A,Chr4B_39664164_A / G,Chr4B_39664167_G / A,Chr4B_39664169_G / A,Chr4B_39664176_C / T,Chr4B_39664189_C / G,Chr4B_39664200_G / A,Chr4B_39664205_C / G,Chr4B_39664218_A / G,Chr4B_39664227_T / C,Chr4B_39664261_C / T,Chr4B_39664291_A / G,Chr4B_39664293_T / C,Chr4B_39664297_G / A,Chr4B_39664338_C / G,Chr4B_39664341_C / T,Chr4B_39664345_T / A,Chr4B_39664398_C / T,Chr4B_39664399_A / G,Chr4B_39664409_G / A,Chr4B_39664416_T / A,Chr4B_39664434_A / G,Chr4B_39664439_G / A,Chr4B_39664448_A / G,Chr4B_39664451_T / A,Chr4B_39664484_T / A,Chr4B_39664486_A / G,Chr4B_39664614_C / A,Chr4B_39664657_C / A,Chr4B_39664660_C / T,Chr4B_39664662_T / G,Chr4B_39664704_A / G,Chr4B_39664711_C / G,Chr4B_39664714_A / G,Chr4B_39664720_C / T,Chr4B_39664721_A / G,Chr4B_39664738_C / G,Chr4B_39664750_C / T,Chr4B_39664754_C / A,Chr4B_39664849_T / C,Chr4B_39664862_A / G,Chr4B_39664909_G / A,Chr4B_39664910_G / C,Chr4B_39664914_T / C,Chr4B_39665000_T / C,Chr4B_39665039_C / G,Chr4B_39665056_T / A,Chr4B_39665067_C / T,Chr4B_39665070_A / G,Chr4B_39665080_C / A,Chr4B_39665146_G / A,Chr4B_39665151_A / G,Chr4B_39665162_T / A,Chr4B_39665194_T / C,Chr4B_39665207_C / G,Chr4B_39665239_G / A,Chr4B_39665260_G / C,Chr4B_39665261_A / G,Chr4B_39665294_G / A,Chr4B_39665323_T / A,Chr4B_39665332_C / G,Chr4B_39665343_A / C,Chr4B_39665361_G / A,Chr4B_39665384_G / T,Chr4B_39665405_T / C,Chr4B_39665406_G / A,Chr4B_39665412_C / A,Chr4B_39665498_C / T,Chr4B_39708890_A / G,Chr4B_39714574_T / C,Chr4B_39716545_G / T,Chr4B_39716546_G / C,Chr4B_39748682_G / A,Chr4B_39768400_C / T,Chr4B_39781373_C / T,Chr4B_39781388_T / G,Chr4B_39781390_A / C,Chr4B_39781414_T / A,Chr4B_39783370_A / T,Chr4B_39785289_C / G,Chr4B_39785309_A / G,Chr4B_39868027_C / T,Chr4B_39882799_T / G,Chr4B_39882903_C / T,Chr4B_39882973_A / T,Chr4B_39882975_C / G,Chr4B_39882992_G / A,Chr4B_39895955_C / T,Chr4B_39895956_T / G,Chr4B_39903957_G / C,Chr4B_39967960_A / C,Chr4B_39967999_C / T,Chr4B_39975151_C / G,Chr4B_39975300_A / C,Chr4B_39975385_T / A,Chr4B_39975389_A / T,Chr4B_39975707_A / T,Chr4B_39975734_A / C,Chr4B_39975815_T / G,Chr4B_39975842_A / G,Chr4B_39981172_A / T,Chr4B_39981311_G / A,Chr4B_39981312_A / C,Chr4B_39981343_G / C,Chr4B_39981557_A / C,Chr4B_39981567_G / A,Chr4B_39981633_A / G,Chr4B_39981649_C / T,Chr4B_39981819_G / C,Chr4B_39981962_G / A,Chr4B_39982038_T / G,Chr4B_39982041_C / T,Chr4B_39982050_A / G,Chr4B_39982070_A / G,Chr4B_39982081_A / G,Chr4B_39982124_A / G,Chr4B_39982139_T / G,Chr4B_39982203_A / T,Chr4B_39982342_C / T,Chr4B_39982354_T / A,Chr4B_39982452_G / T,Chr4B_39982481_A / G,Chr4B_39982487_A / T,Chr4B_39982503_G / T,Chr4B_39982529_A / G,Chr4B_39982533_C / A,Chr4B_39982649_G / T,Chr4B_39982657_G / C,Chr4B_39982824_C / T,Chr4B_39982847_T / G,Chr4B_39982944_A / G,Chr4B_39986845_A / T,Chr4B_39986901_T / C,Chr4B_40014841_T / A,Chr4B_40080515_A / T,Chr4B_40094983_G / A,Chr4B_40095048_C / T,Chr4B_40095123_G / T,Chr4B_40095152_G / A,Chr4B_40095170_A / T,Chr4B_40095250_A / G,Chr4B_40095279_C / T,Chr4B_40095284_T / A,Chr4B_40095360_C / T,Chr4B_40106784_A / G,Chr4B_40106789_C / T,Chr4B_40106812_G / A,Chr4B_40106818_C / A,Chr4B_40106949_C / A,Chr4B_40106951_A / C,Chr4B_40106954_A / G,Chr4B_40106961_G / A,Chr4B_40107148_C / A,Chr4B_40107184_T / G,Chr4B_40122068_T / C,Chr4B_40122080_C / T,Chr4B_40122129_A / G,Chr4B_40156147_G / A,Chr4B_40166999_C / A,Chr4B_40168292_C / T,Chr4B_40168337_G / A,Chr4B_40168376_G / C,Chr4B_40203364_C / T,Chr4B_40211323_C / A,Chr4B_40211441_C / T,Chr4B_40211473_C / T,Chr4B_40211489_A / T,Chr4B_40211569_A / C,Chr4B_40211574_T / G,Chr4B_40211575_T / G,Chr4B_40229024_T / C,Chr4B_40229054_A / G,Chr4B_40245492_A / G,Chr4B_40245526_G / A,Chr4B_40245535_C / A,Chr4B_40245566_T / C,Chr4B_40245571_T / A,Chr4B_40245703_C / G,Chr4B_40273269_A / G,Chr4B_40273296_G / C,Chr4B_40406125_G / A,Chr4B_40406147_A / T,Chr4B_40412586_G / A,Chr4B_40412666_G / T,Chr4B_40412766_G / T,Chr4B_40412844_T / G,Chr4B_40412946_A / G,Chr4B_40413004_C / T,Chr4B_40413013_G / A,Chr4B_40413066_G / A,Chr4B_40413090_C / G,Chr4B_40513490_T / G,Chr4B_40513670_G / C,Chr4B_40513814_G / C,Chr4B_40575106_C / T,Chr4B_40576087_C / A,Chr4B_40576089_G / A,Chr4B_40576104_G / A,Chr4B_40576132_T / G,Chr4B_40576153_T / A,Chr4B_40576268_G / A,Chr4B_40576280_C / A,Chr4B_40576301_C / T,Chr4B_40576308_A / T,Chr4B_40576430_C / T,Chr4B_40589497_G / A,Chr4B_40589564_A / G,Chr4B_40590316_G / A,Chr4B_40590383_G / A,Chr4B_40590456_G / T,Chr4B_40672153_A / G,Chr4B_40672166_C / A,Chr4B_40672207_T / A,Chr4B_40760456_T / C,Chr4B_40780136_A / C,Chr4B_40780142_A / T,Chr4B_40780180_G / C,Chr4B_40780183_C / T,Chr4B_40781793_A / T,Chr4B_40781833_G / A,Chr4B_40781840_A / T,Chr4B_40781855_G / A,Chr4B_40781872_A / T,Chr4B_40781877_G / A,Chr4B_40781884_A / T,Chr4B_40781894_G / A,Chr4B_40781908_T / A,Chr4B_40792650_C / T,Chr4B_40837437_T / A,Chr4B_40837439_C / G,Chr4B_40837501_A / T,Chr4B_40837522_C / T,Chr4B_40837524_C / T,Chr4B_40837525_G / A,Chr4B_40837534_A / T,Chr4B_40837535_G / A,Chr4B_40837575_T / C,Chr4B_40837620_G / T,Chr4B_48398333_C / G,Chr4B_48398342_T / C,Chr4B_48398346_A / G,Chr4B_48398351_T / G,Chr4B_48398439_C / A,Chr4B_48398464_C / A,Chr4B_48398506_A / C,Chr4B_48398550_A / T,Chr4B_48398585_G / T,Chr4B_48398663_C / T,Chr4B_48398674_A / G,Chr4B_48398747_G / T,Chr4B_48398763_G / A,Chr4B_48398890_T / C,Chr4B_48398901_G / C,Chr4B_48398962_T / C,Chr4B_48399007_T / C,Chr4B_48399008_G / A,Chr4B_48399076_T / G,Chr4B_48399142_G / A,Chr4B_48399146_T / C,Chr4B_48399202_G / A,Chr4B_48399209_T / G,Chr4B_48399238_G / A,Chr4B_48399326_C / T,Chr4B_48399337_T / G,Chr4B_48399357_G / C,Chr4B_48399619_A / T,Chr4B_48399657_T / C,Chr4B_48399677_G / A,Chr4B_48399683_A / T,Chr4B_48399687_C / A,Chr4B_48399703_T / G,Chr4B_48399752_C / G,Chr4B_48399759_G / T,Chr4B_48408783_C / T,Chr4B_48414268_C / A,Chr4B_48414325_C / T,Chr4B_48415051_A / G,Chr4B_48434245_G / A,Chr4B_48440686_C / G,Chr4B_48440919_G / T,Chr4B_48440927_C / T,Chr4B_48441084_A / C,Chr4B_48441102_G / A,Chr4B_48441103_G / A,Chr4B_48441128_T / A,Chr4B_48441146_G / T,Chr4B_48441167_G / A,Chr4B_48441182_A / G,Chr4B_48441208_A / G,Chr4B_48441267_T / G,Chr4B_48441275_C / T,Chr4B_48441276_A / G,Chr4B_48441397_A / G,Chr4B_48441409_T / A,Chr4B_48441722_C / A,Chr4B_48441740_C / T,Chr4B_48441754_A / C,Chr4B_48441855_A / G,Chr4B_48441921_A / G,Chr4B_48441960_C / T,Chr4B_48442068_C / G,Chr4B_48442086_T / G,Chr4B_48442116_G / A,Chr4B_48442508_G / T,Chr4B_48442523_T / C,Chr4B_48442688_T / G,Chr4B_48442780_A / C,Chr4B_48442837_C / T,Chr4B_48442843_T / C,Chr4B_48442876_G / A,Chr4B_48442884_T / C,Chr4B_48443018_T / C,Chr4B_48443031_A / C,Chr4B_48443055_G / A,Chr4B_48443139_T / A,Chr4B_48443184_G / A,Chr4B_48443207_G / C,Chr4B_48443343_T / A,Chr4B_48443398_A / T,Chr4B_48443421_A / C,Chr4B_48443554_A / G,Chr4B_48443673_G / C,Chr4B_48443692_T / A,Chr4B_48443939_T / C,Chr4B_48444128_G / T,Chr4B_48444266_T / C,Chr4B_48444269_C / G,Chr4B_48444280_T / G,Chr4B_48444283_A / G,Chr4B_48444293_A / C,Chr4B_48444321_T / A,Chr4B_48444424_G / A,Chr4B_48444427_T / A,Chr4B_48444449_G / T,Chr4B_48444515_C / G,Chr4B_48444764_T / C,Chr4B_48444800_G / A,Chr4B_48444806_G / T,Chr4B_48447155_C / T,Chr4B_48447179_T / C,Chr4B_48447202_T / A,Chr4B_48447213_C / T,Chr4B_48447215_A / G,Chr4B_48447221_C / T,Chr4B_48447460_C / T,Chr4B_48447479_C / T,Chr4B_48447713_C / T,Chr4B_48447950_G / T,Chr4B_48447962_T / C,Chr4B_48448204_T / A,Chr4B_48448442_T / C,Chr4B_48448454_T / C,Chr4B_48448494_T / A,Chr4B_48448905_A / T,Chr4B_48449112_T / C,Chr4B_48449143_C / T,Chr4B_48449219_C / T,Chr4B_48449245_C / G,Chr4B_48449361_A / T,Chr4B_48449598_G / A,Chr4B_48449644_A / G,Chr4B_48449720_A / T,Chr4B_48449765_C / T,Chr4B_48449997_A / T,Chr4B_48450034_A / T,Chr4B_48450195_C / G,Chr4B_48450368_C / A,Chr4B_48450395_G / T,Chr4B_48450411_A / T,Chr4B_48450418_A / T,Chr4B_48450437_A / T,Chr4B_48450466_G / C,Chr4B_48450493_A / C,Chr4B_48450513_C / A,Chr4B_48450618_A / C,Chr4B_48450750_T / G,Chr4B_48450752_C / G,Chr4B_48450898_T / G,Chr4B_48451178_T / C,Chr4B_48451189_C / A,Chr4B_48451190_A / T,Chr4B_48451346_C / G,Chr4B_48451352_A / G,Chr4B_48451796_C / T,Chr4B_48452732_A / G,Chr4B_48452830_A / G,Chr4B_48452832_A / G,Chr4B_48453036_G / A,Chr4B_48453122_G / A,Chr4B_48473268_T / G,Chr4B_48473293_A / G,Chr4B_48473297_G / A,Chr4B_48473352_A / G,Chr4B_48473393_A / C,Chr4B_48473419_C / T,Chr4B_48473420_T / G,Chr4B_48473422_C / A,Chr4B_48473430_A / T,Chr4B_48473491_A / G,Chr4B_48473504_C / T,Chr4B_48473602_T / C,Chr4B_48473614_A / T,Chr4B_48473634_C / G,Chr4B_48473651_G / A,Chr4B_48473655_G / A,Chr4B_48473673_T / A,Chr4B_48473732_C / A,Chr4B_48473778_C / T,Chr4B_48473795_G / T,Chr4B_48473811_C / T,Chr4B_48473849_G / T,Chr4B_48473853_A / C,Chr4B_48473873_T / C,Chr4B_48473921_A / C,Chr4B_48474077_T / C,Chr4B_48474092_G / A,Chr4B_48474102_G / A,Chr4B_48474124_T / A,Chr4B_48474188_T / C,Chr4B_48474416_T / G,Chr4B_48474440_T / C,Chr4B_48474632_A / T,Chr4B_48474703_T / A,Chr4B_48474715_C / G,Chr4B_48474739_T / C,Chr4B_48474852_C / T,Chr4B_48474865_G / T,Chr4B_48474903_A / G,Chr4B_48474947_G / A,Chr4B_48475086_A / G,Chr4B_48475167_T / G,Chr4B_48475181_A / T,Chr4B_48475182_A / T,Chr4B_48475183_C / T,Chr4B_48475193_T / C,Chr4B_48475226_T / C,Chr4B_48475249_G / A,Chr4B_48475250_A / G,Chr4B_48475260_G / A,Chr4B_48475272_T / C,Chr4B_48475275_A / T,Chr4B_48475289_A / G,Chr4B_48475301_C / T,Chr4B_48475302_A / G,Chr4B_48475304_C / G,Chr4B_48475307_T / A,Chr4B_48475326_A / G,Chr4B_48475458_G / A,Chr4B_48475502_A / G,Chr4B_48475730_C / T,Chr4B_48475906_G / C,Chr4B_48476009_A / G,Chr4B_48476915_C / G,Chr4B_48477242_G / A,Chr4B_48477426_A / T,Chr4B_48477480_C / T,Chr4B_48477608_G / A,Chr4B_48477684_A / G,Chr4B_48477752_T / C,Chr4B_48477929_A / G,Chr4B_48477942_T / A,Chr4B_48477943_A / T,Chr4B_48478038_T / G,Chr4B_48478333_G / T,Chr4B_48478419_A / G,Chr4B_48478423_T / A,Chr4B_48478431_T / C,Chr4B_48478456_C / T,Chr4B_48478496_C / T,Chr4B_48478709_T / C,Chr4B_48478760_T / A,Chr4B_48478920_T / C,Chr4B_48479035_G / A,Chr4B_48479092_C / T,Chr4B_48479330_A / T,Chr4B_48479560_T / C,Chr4B_48479713_A / T,Chr4B_48479795_T / C,Chr4B_48480394_C / T,Chr4B_48480601_G / A,Chr4B_48480607_C / T,Chr4B_48480924_T / A,Chr4B_48480932_A / G,Chr4B_48481041_G / C,Chr4B_48481126_T / C,Chr4B_48481298_T / C,Chr4B_48481314_A / G,Chr4B_48481747_A / T,Chr4B_48481833_C / T,Chr4B_48481867_T / C,Chr4B_48481946_T / A,Chr4B_48482170_A / C,Chr4B_48482188_C / G,Chr4B_48482301_C / T,Chr4B_48482305_T / C,Chr4B_48482817_A / T,Chr4B_48482822_C / T,Chr4B_48482963_T / A,Chr4B_48482973_C / T,Chr4B_48483109_T / C,Chr4B_48483284_G / A,Chr4B_48483290_A / G,Chr4B_48483426_G / A,Chr4B_48483539_T / C,Chr4B_48483747_C / A,Chr4B_48483786_T / C,Chr4B_48483812_C / T,Chr4B_48483867_C / T,Chr4B_48483869_T / A,Chr4B_48485325_G / T,Chr4B_48485344_C / T,Chr4B_48485366_G / A,Chr4B_48485497_G / C,Chr4B_48485621_A / G,Chr4B_48485882_G / A,Chr4B_48485970_G / A,Chr4B_48486508_A / G,Chr4B_48486509_A / G,Chr4B_48486547_T / C,Chr4B_48486780_G / T,Chr4B_48486803_A / G,Chr4B_48486807_G / A,Chr4B_48486821_T / G,Chr4B_48486831_A / T,Chr4B_48486947_C / T,Chr4B_48486949_G / A,Chr4B_48486969_C / T,Chr4B_48486976_A / T,Chr4B_48486982_G / C,Chr4B_48487113_T / G,Chr4B_48487140_C / T,Chr4B_48487169_C / G,Chr4B_48487184_T / C,Chr4B_48487234_C / A,Chr4B_48487283_A / T,Chr4B_48487299_A / C,Chr4B_48487319_T / A,Chr4B_48487332_T / A,Chr4B_48487346_A / C,Chr4B_48487359_T / A,Chr4B_48487382_C / T,Chr4B_48487429_A / C,Chr4B_48487462_G / T,Chr4B_48487475_C / T,Chr4B_48487476_T / G,Chr4B_48487554_G / C,Chr4B_48487583_T / A,Chr4B_48487589_T / A,Chr4B_48487591_G / A,Chr4B_48487668_G / A,Chr4B_48487693_T / C,Chr4B_48487839_G / A,Chr4B_48487899_G / A,Chr4B_48487963_G / A,Chr4B_48487971_C / T,Chr4B_48487977_C / G,Chr4B_48488022_T / A,Chr4B_48488074_C / G,Chr4B_48488152_G / C,Chr4B_48488301_A / G,Chr4B_48488312_G / A,Chr4B_48488326_G / A,Chr4B_48488329_T / C,Chr4B_48488363_T / G,Chr4B_48488382_A / C,Chr4B_48488397_T / C,Chr4B_48488448_C / G,Chr4B_48488499_G / T,Chr4B_48488504_G / A,Chr4B_48488678_G / C,Chr4B_48488710_T / G,Chr4B_48488725_G / A,Chr4B_48488803_C / A,Chr4B_48488872_A / G,Chr4B_48489131_A / G,Chr4B_48489177_G / T,Chr4B_48489209_G / C,Chr4B_48489262_A / G,Chr4B_48489271_G / A,Chr4B_48489442_C / T,Chr4B_48489449_G / A,Chr4B_48489633_A / C,Chr4B_48489734_C / A,Chr4B_48489751_A / G,Chr4B_48489782_G / A,Chr4B_48489846_A / T,Chr4B_48490582_T / C,Chr4B_48490698_G / A,Chr4B_48490796_C / T,Chr4B_48490850_A / G,Chr4B_48490925_C / T,Chr4B_48491445_A / G,Chr4B_48491455_T / C,Chr4B_48491517_G / A,Chr4B_48491522_T / A,Chr4B_48491528_T / A,Chr4B_48491555_A / G,Chr4B_48491631_C / T,Chr4B_48491730_A / T,Chr4B_48491742_A / G,Chr4B_48491748_T / C,Chr4B_48492733_T / G,Chr4B_48492776_A / C,Chr4B_48492779_T / C,Chr4B_48492810_T / C,Chr4B_48492830_T / G,Chr4B_48492881_T / C,Chr4B_48493081_A / G,Chr4B_48493169_A / G,Chr4B_48493399_T / A,Chr4B_48493596_T / C,Chr4B_48493602_C / A,Chr4B_48493723_T / C,Chr4B_48493765_A / G,Chr4B_48493782_A / G,Chr4B_48493844_T / C,Chr4B_48493848_G / A,Chr4B_48493855_A / G,Chr4B_48493897_C / G,Chr4B_48493966_T / G,Chr4B_48493984_G / A,Chr4B_48493993_T / C,Chr4B_48494011_T / C,Chr4B_48494029_G / C,Chr4B_48494044_G / A,Chr4B_48494086_G / A,Chr4B_48494125_T / C,Chr4B_48494167_C / T,Chr4B_48494185_T / C,Chr4B_48494240_G / T,Chr4B_48494370_A / G,Chr4B_48494409_A / G,Chr4B_48494709_G / C,Chr4B_48494804_C / T,Chr4B_48494965_A / G,Chr4B_48495090_A / G,Chr4B_48495122_G / C,Chr4B_48495291_G / A,Chr4B_48496273_G / C,Chr4B_48496450_A / G,Chr4B_48496696_C / T,Chr4B_48497101_T / C,Chr4B_48497207_C / T,Chr4B_48497354_G / A,Chr4B_48497384_T / C,Chr4B_48497385_C / A,Chr4B_48497483_T / C,Chr4B_48497565_G / A,Chr4B_48497580_T / C,Chr4B_48497678_G / A,Chr4B_48497759_C / T,Chr4B_48497924_G / A,Chr4B_48498314_G / T,Chr4B_48498554_C / T,Chr4B_48498556_T / C,Chr4B_48498599_G / A,Chr4B_48498642_A / T,Chr4B_48498678_G / A,Chr4B_48498683_G / A,Chr4B_48498718_A / C,Chr4B_48499142_G / A,Chr4B_48499349_T / G,Chr4B_48499414_C / T,Chr4B_48499453_G / C,Chr4B_48499454_A / C,Chr4B_48499522_C / T,Chr4B_48499557_A / C,Chr4B_48499558_A / T,Chr4B_48499577_G / C,Chr4B_48499638_C / T,Chr4B_48499742_G / C,Chr4B_48499757_C / T,Chr4B_48499759_C / A,Chr4B_48499835_G / A,Chr4B_48499871_T / C,Chr4B_48499908_C / T,Chr4B_48499917_C / G,Chr4B_48499950_T / C,Chr4B_48499964_T / G,Chr4B_48499991_T / C,Chr4B_48500001_T / C,Chr4B_48500017_A / C,Chr4B_48500037_A / G,Chr4B_48500045_A / T,Chr4B_48500054_A / G,Chr4B_48500080_A / G,Chr4B_48500089_G / A,Chr4B_48500100_T / G,Chr4B_48500107_G / T,Chr4B_48500113_T / C,Chr4B_48500348_T / C,Chr4B_48500368_A / G,Chr4B_48500414_G / A,Chr4B_48500439_T / A,Chr4B_48500599_T / C,Chr4B_48500605_A / C,Chr4B_48500609_T / A,Chr4B_48500679_A / T,Chr4B_48500753_G / C,Chr4B_48500915_G / A,Chr4B_48501077_T / G,Chr4B_48501490_A / G,Chr4B_48501514_A / C,Chr4B_48501716_C / T,Chr4B_48501749_G / T,Chr4B_48501865_A / G,Chr4B_48502223_A / G,Chr4B_48502308_G / A,Chr4B_48502310_T / C,Chr4B_48502322_A / C,Chr4B_48502327_T / A,Chr4B_48520903_A / G,Chr4B_48520914_A / C,Chr4B_48520942_A / G,Chr4B_48520964_C / T,Chr4B_48521010_A / G,Chr4B_48521023_G / C,Chr4B_48521026_A / T,Chr4B_48521100_T / A,Chr4B_48521138_C / G,Chr4B_48521154_C / T,Chr4B_48521155_C / T,Chr4B_48521159_G / T,Chr4B_48521174_T / C,Chr4B_48521262_A / G,Chr4B_48521270_C / T,Chr4B_48521286_T / A,Chr4B_48521337_A / G,Chr4B_48521351_C / T,Chr4B_48521353_G / A,Chr4B_48521369_T / C,Chr4B_48521556_T / G,Chr4B_48521693_C / T,Chr4B_48529591_A / G,Chr4B_48529691_T / C,Chr4B_48529711_G / C,Chr4B_48529752_G / C,Chr4B_48529873_G / A,Chr4B_48529891_C / T,Chr4B_48530033_A / G,Chr4B_48531889_A / G,Chr4B_48531910_G / A,Chr4B_48531921_T / A,Chr4B_48532018_T / A,Chr4B_48532038_T / A,Chr4B_48532155_T / C,Chr4B_48532156_T / C,Chr4B_48532160_G / A,Chr4B_48532167_G / T,Chr4B_48532173_G / T,Chr4B_48532266_A / G,Chr4B_48532268_A / G,Chr4B_48532270_C / T,Chr4B_48532275_G / A,Chr4B_48532300_T / C,Chr4B_48532319_G / A,Chr4B_48532331_G / T,Chr4B_48532395_G / A,Chr4B_48532435_G / A,Chr4B_48532452_C / T,Chr4B_48532459_A / G,Chr4B_48532467_T / C,Chr4B_48532470_G / A,Chr4B_48532728_C / T,Chr4B_48532761_C / G,Chr4B_48532813_G / C,Chr4B_48534555_G / C,Chr4B_48535204_A / G,Chr4B_48535307_A / G,Chr4B_48535311_C / T,Chr4B_48535464_A / G,Chr4B_48535511_T / C,Chr4B_48535518_G / A,Chr4B_48535543_A / G,Chr4B_48535545_T / A,Chr4B_48535621_A / G,Chr4B_48535631_G / A,Chr4B_48535706_C / T,Chr4B_48535942_A / C,Chr4B_48536010_G / A,Chr4B_48536189_A / G,Chr4B_48536249_A / G,Chr4B_48536377_G / A,Chr4B_48536379_T / G,Chr4B_48536414_A / T,Chr4B_48536721_G / T,Chr4B_48536950_C / A,Chr4B_48537045_G / A,Chr4B_48537094_A / G,Chr4B_48537127_C / T,Chr4B_48537132_A / G,Chr4B_48537220_C / T,Chr4B_48537234_C / G,Chr4B_48537343_A / G,Chr4B_48537346_A / G,Chr4B_48537365_A / G,Chr4B_48537458_G / A,Chr4B_48537637_G / A,Chr4B_48537706_A / G,Chr4B_48537849_G / A,Chr4B_48537854_A / G,Chr4B_48537858_C / G,Chr4B_48537986_G / A,Chr4B_48538073_A / G,Chr4B_48538074_G / A,Chr4B_48538104_G / A,Chr4B_48538115_A / T,Chr4B_48538116_T / C,Chr4B_48538232_C / G,Chr4B_48538238_G / A,Chr4B_48538261_T / C,Chr4B_48538341_C / T,Chr4B_48538596_C / T,Chr4B_48538614_T / G,Chr4B_48538643_C / G,Chr4B_48538649_C / T,Chr4B_48538692_T / G,Chr4B_48538816_T / A,Chr4B_48538879_T / C,Chr4B_48539219_A / T,Chr4B_48539234_G / A,Chr4B_48539246_T / A,Chr4B_48539266_A / G,Chr4B_48539410_T / G,Chr4B_48539623_C / T,Chr4B_48539723_G / C,Chr4B_48539813_A / G,Chr4B_48539994_C / A,Chr4B_48540087_A / G,Chr4B_48540088_A / C,Chr4B_48540105_T / G,Chr4B_48540138_A / G,Chr4B_48540151_C / G,Chr4B_48540159_A / G,Chr4B_48540433_T / G,Chr4B_48540605_T / C,Chr4B_48540706_A / G,Chr4B_48540884_T / C,Chr4B_48540901_G / A,Chr4B_48540909_T / C,Chr4B_48541051_T / C,Chr4B_48541082_G / T,Chr4B_48541114_C / T,Chr4B_48541148_A / G,Chr4B_48541264_G / A,Chr4B_48541383_T / C,Chr4B_48541485_C / T,Chr4B_48541492_G / A,Chr4B_48541558_C / G,Chr4B_48541574_G / T,Chr4B_48541575_A / C,Chr4B_48541677_A / T,Chr4B_48541799_A / C,Chr4B_48541807_G / A,Chr4B_48541830_C / T,Chr4B_48541915_G / T,Chr4B_48541937_T / C,Chr4B_48541951_T / G,Chr4B_48541953_T / A,Chr4B_48541998_A / G,Chr4B_48542022_G / A,Chr4B_48542080_G / A,Chr4B_48542158_T / G,Chr4B_48542224_T / C,Chr4B_48542228_C / A,Chr4B_48542238_A / G,Chr4B_48542295_C / T,Chr4B_48542299_G / A,Chr4B_48542519_T / A,Chr4B_48542662_A / T,Chr4B_48542688_G / A,Chr4B_48542696_T / C,Chr4B_48542697_T / C,Chr4B_48542802_G / T,Chr4B_48543630_C / A,Chr4B_48549008_C / T,Chr4B_48551128_A / G,Chr4B_48551145_A / T,Chr4B_48551157_C / T,Chr4B_48551181_T / C,Chr4B_48551183_A / C,Chr4B_48551200_C / G,Chr4B_48551208_C / T,Chr4B_48551212_C / T,Chr4B_48551235_C / T,Chr4B_48551264_T / A,Chr4B_48551336_A / G,Chr4B_48551393_G / A,Chr4B_48551527_G / A,Chr4B_48566281_T / G,Chr4B_48566771_A / C,Chr4B_48566773_T / G,Chr4B_48566774_G / C,Chr4B_48566790_T / C,Chr4B_48566813_C / G,Chr4B_48566816_T / G,Chr4B_48566918_C / T,Chr4B_48567073_G / T,Chr4B_48567345_T / C,Chr4B_48567346_T / C,Chr4B_48567541_T / C,Chr4B_48567665_G / C,Chr4B_48567678_T / C,Chr4B_48567679_A / G,Chr4B_48567850_T / C,Chr4B_48567906_G / A,Chr4B_48567934_T / C,Chr4B_48567942_A / C,Chr4B_48568013_C / G,Chr4B_48568162_A / C,Chr4B_48568165_C / A,Chr4B_48568230_C / G,Chr4B_48568254_T / C,Chr4B_48568265_A / G,Chr4B_48568285_A / G,Chr4B_48568341_C / A,Chr4B_48568362_C / A,Chr4B_48568377_T / G,Chr4B_48568378_T / A,Chr4B_48568404_T / A,Chr4B_48568408_G / T,Chr4B_48568506_C / A,Chr4B_48568514_C / T,Chr4B_48568571_T / C,Chr4B_48568642_G / A,Chr4B_48568651_G / C,Chr4B_48568665_G / A,Chr4B_48568671_C / T,Chr4B_48568677_T / C,Chr4B_48568693_A / T,Chr4B_48568715_G / T,Chr4B_48568723_G / A,Chr4B_48568736_A / G,Chr4B_48572245_C / T,Chr4B_48572249_C / T,Chr4B_48572253_T / C,Chr4B_48572266_C / T,Chr4B_48572306_G / A,Chr4B_48572377_A / G,Chr4B_48572383_T / C,Chr4B_48572385_A / G,Chr4B_48572417_A / T,Chr4B_48572541_T / C,Chr4B_48572556_T / C,Chr4B_48572659_T / G,Chr4B_48572722_G / A,Chr4B_48572752_T / C,Chr4B_48572784_G / C,Chr4B_48572788_T / C,Chr4B_48572870_G / A,Chr4B_48572876_T / C,Chr4B_48572995_A / C,Chr4B_48573018_G / A,Chr4B_48573024_A / G,Chr4B_48573038_T / G,Chr4B_48573077_T / A,Chr4B_48573078_T / G,Chr4B_48574220_C / T,Chr4B_48574327_G / T,Chr4B_48574378_T / G,Chr4B_48574396_G / A,Chr4B_48574400_A / G,Chr4B_48574436_A / C,Chr4B_48574442_G / T,Chr4B_48574533_C / G,Chr4B_48574549_A / T,Chr4B_48574613_T / C,Chr4B_48574646_A / T,Chr4B_48574687_G / A,Chr4B_48574703_T / G,Chr4B_48574712_C / T,Chr4B_48574767_T / A,Chr4B_48574793_T / C,Chr4B_48574794_G / A,Chr4B_48574999_G / A,Chr4B_48575024_A / T,Chr4B_48575248_T / C,Chr4B_48575249_T / C,Chr4B_48575256_T / C,Chr4B_48575272_A / G,Chr4B_48575410_C / T,Chr4B_48575430_T / C,Chr4B_48575440_T / C,Chr4B_48575441_C / T,Chr4B_48575459_C / T,Chr4B_48575463_A / C,Chr4B_48575470_G / A,Chr4B_48575492_T / A,Chr4B_48575507_T / A,Chr4B_48575627_C / T,Chr4B_48575675_C / G,Chr4B_48575765_C / T,Chr4B_48575783_A / T,Chr4B_48575785_A / G,Chr4B_48575787_C / T,Chr4B_48575791_G / A,Chr4B_48575799_T / C,Chr4B_48575805_G / T,Chr4B_48575808_A / G,Chr4B_48575813_T / A,Chr4B_48575819_G / A,Chr4B_48575825_G / T,Chr4B_48575836_T / G,Chr4B_48575842_T / A,Chr4B_48575849_T / C,Chr4B_48575850_C / G,Chr4B_48575860_G / A,Chr4B_48575864_G / A,Chr4B_48575917_C / T,Chr4B_48575943_A / C,Chr4B_48575944_C / T,Chr4B_48575947_G / A,Chr4B_48575959_A / G,Chr4B_48575961_T / C,Chr4B_48575980_G / A,Chr4B_48575982_G / A,Chr4B_48575984_T / C,Chr4B_48575995_T / G,Chr4B_48576013_C / T,Chr4B_48576015_A / T,Chr4B_48576018_C / G,Chr4B_48576021_T / A,Chr4B_48576029_A / G,Chr4B_48576130_G / C,Chr4B_48576161_C / G,Chr4B_48576163_A / T,Chr4B_48576259_G / A,Chr4B_48576281_G / C,Chr4B_48576289_T / C,Chr4B_48576312_G / C,Chr4B_48576345_G / A,Chr4B_48576365_G / T,Chr4B_48576411_C / T,Chr4B_48576436_A / C,Chr4B_48576488_G / A,Chr4B_48576498_C / G,Chr4B_48576590_C / T,Chr4B_48576756_C / G,Chr4B_48577228_C / T,Chr4B_48577262_C / T,Chr4B_48577311_C / A,Chr4B_48577317_A / G,Chr4B_48577341_G / A,Chr4B_48577400_C / T,Chr4B_48577515_G / A,Chr4B_48577526_C / T,Chr4B_48577527_A / G,Chr4B_48577556_C / T,Chr4B_48577571_G / A,Chr4B_48577580_A / G,Chr4B_48577596_T / C,Chr4B_48577610_T / G,Chr4B_48577664_G / A,Chr4B_48577674_A / G,Chr4B_48577693_G / A,Chr4B_48577706_A / G,Chr4B_48577715_A / C,Chr4B_48577717_A / G,Chr4B_48577739_C / A,Chr4B_48577794_G / A,Chr4B_48577910_A / T,Chr4B_48579697_G / A,Chr4B_48579700_A / C,Chr4B_48584481_A / G,Chr4B_48584495_G / A,Chr4B_48584501_A / T,Chr4B_48584505_G / A,Chr4B_48584525_T / C,Chr4B_48584541_C / G,Chr4B_48584841_T / G,Chr4B_48584907_A / G,Chr4B_48584956_G / A,Chr4B_48584964_C / T,Chr4B_48585048_C / T,Chr4B_48585113_G / A,Chr4B_48585204_C / T,Chr4B_48585227_G / C,Chr4B_48585228_T / A,Chr4B_48585292_G / T,Chr4B_48585566_T / C,Chr4B_48585586_A / G,Chr4B_48585589_G / C,Chr4B_48585642_G / A,Chr4B_48585659_T / C,Chr4B_48585661_G / A,Chr4B_48585681_T / C,Chr4B_48585689_A / G,Chr4B_48585697_T / G,Chr4B_48585722_C / G,Chr4B_48585727_C / T,Chr4B_48585732_A / G,Chr4B_48585835_G / C,Chr4B_48585840_T / C,Chr4B_48585846_A / G,Chr4B_48585857_T / G,Chr4B_48585927_T / C,Chr4B_48585974_T / C,Chr4B_48586105_C / T,Chr4B_48586286_A / C,Chr4B_48586288_A / T,Chr4B_48586342_T / C,Chr4B_48586349_A / T,Chr4B_48586514_A / G,Chr4B_48586544_G / A,Chr4B_48586621_T / C,Chr4B_48586664_G / A,Chr4B_48586717_G / T,Chr4B_48586728_T / C,Chr4B_48586812_A / G,Chr4B_48586813_G / A,Chr4B_48586899_A / G,Chr4B_48586903_G / T,Chr4B_48586937_A / G,Chr4B_48586960_G / A,Chr4B_48587038_G / C,Chr4B_48587045_A / G,Chr4B_48587074_C / T,Chr4B_48587084_T / C,Chr4B_48593506_A / T,Chr4B_48602966_A / G,Chr4B_48602968_C / T,Chr4B_48613469_T / A,Chr4B_48613473_A / C,Chr4B_48613477_T / A,Chr4B_48613492_T / C,Chr4B_48613499_G / T,Chr4B_48613698_C / T,Chr4B_48613729_C / T,Chr4B_48613744_T / A,Chr4B_48613745_A / G,Chr4B_48613767_G / A,Chr4B_48613775_G / A,Chr4B_48613786_A / G,Chr4B_48613816_T / G,Chr4B_48613831_G / C,Chr4B_48613909_T / G,Chr4B_48613912_C / T,Chr4B_48613953_G / A,Chr4B_48613998_C / T,Chr4B_48614020_G / A,Chr4B_48614052_C / T,Chr4B_48614068_C / G,Chr4B_48614467_T / G,Chr4B_48614511_G / A,Chr4B_48614535_T / G,Chr4B_48614673_A / G,Chr4B_48614759_T / A,Chr4B_48614791_C / G,Chr4B_48614819_A / T,Chr4B_48614891_T / G,Chr4B_48615592_T / C,Chr4B_48615593_T / A,Chr4B_48617314_C / A,Chr4B_48617381_G / A,Chr4B_48617498_T / A,Chr4B_48617701_T / A,Chr4B_48617703_C / G,Chr4B_48617746_T / G,Chr4B_48617766_A / G,Chr4B_48617801_A / T,Chr4B_48617805_C / T,Chr4B_48617824_G / A,Chr4B_48617854_G / A,Chr4B_48617863_C / T,Chr4B_48617864_T / C,Chr4B_48617941_G / C,Chr4B_48617944_T / G,Chr4B_48617970_T / A,Chr4B_48618006_A / T,Chr4B_48618091_T / A,Chr4B_48618129_T / A,Chr4B_48618190_C / A,Chr4B_48618592_T / G,Chr4B_48618684_G / A,Chr4B_48618791_G / A,Chr4B_48618815_G / T,Chr4B_48618830_A / C,Chr4B_48618833_C / T,Chr4B_48627659_T / C,Chr4B_48627676_C / T,Chr4B_48627683_G / T,Chr4B_48627715_A / T,Chr4B_48628181_A / G,Chr4B_48628192_T / C,Chr4B_48628204_G / A,Chr4B_48628205_T / G,Chr4B_48628206_G / C,Chr4B_48628243_A / G,Chr4B_48628314_G / A,Chr4B_48628327_A / G,Chr4B_48628342_T / C,Chr4B_48628405_C / T,Chr4B_48628408_A / G,Chr4B_48630964_C / A,Chr4B_48631176_G / C,Chr4B_48631178_C / G,Chr4B_48631304_G / A,Chr4B_48631601_G / A,Chr4B_48634750_C / T,Chr4B_48634790_A / C,Chr4B_48635442_C / T,Chr4B_48635657_G / A,Chr4B_48635660_G / A,Chr4B_48635679_C / T,Chr4B_48635785_T / G,Chr4B_48635929_G / C,Chr4B_48635940_T / C,Chr4B_48636034_T / A,Chr4B_48636069_A / T,Chr4B_48636169_C / A,Chr4B_48636385_C / G,Chr4B_48636459_A / C,Chr4B_48636460_C / T,Chr4B_48636533_C / T,Chr4B_48636538_T / A,Chr4B_48636550_A / C,Chr4B_48636552_T / G,Chr4B_48636619_C / T,Chr4B_48636680_T / A,Chr4B_48636700_G / A,Chr4B_48636702_C / T,Chr4B_48636776_A / G,Chr4B_48636857_T / G,Chr4B_48636862_T / A,Chr4B_48636869_T / C,Chr4B_48636880_C / T,Chr4B_48636996_G / A,Chr4B_48637083_C / G,Chr4B_48637201_C / T,Chr4B_48637271_C / A,Chr4B_48637434_C / G,Chr4B_48637442_A / T,Chr4B_48637478_T / C,Chr4B_48637479_G / C,Chr4B_48637495_T / C,Chr4B_48637499_A / G,Chr4B_48637526_T / C,Chr4B_48637639_T / C,Chr4B_48637713_C / A,Chr4B_48638372_A / G,Chr4B_48638451_T / G,Chr4B_48638475_G / A,Chr4B_48638629_T / C,Chr4B_48638656_A / G,Chr4B_48638698_C / T,Chr4B_48638750_T / C,Chr4B_48638935_A / G,Chr4B_48639166_C / T,Chr4B_48639218_A / G,Chr4B_48639243_A / G,Chr4B_48639317_T / C,Chr4B_48639373_T / A,Chr4B_48639406_T / A,Chr4B_48639415_C / T,Chr4B_48639421_A / G,Chr4B_48639436_C / G,Chr4B_48639479_A / G,Chr4B_48639489_C / T,Chr4B_48639773_G / C,Chr4B_48640097_A / C,Chr4B_48640120_A / G,Chr4B_48640129_C / G,Chr4B_48640135_C / G,Chr4B_48640166_T / C,Chr4B_48640172_C / T,Chr4B_48640175_G / C,Chr4B_48640185_G / T,Chr4B_48640531_C / G,Chr4B_48640606_C / T,Chr4B_48640723_T / C,Chr4B_48640761_G / T,Chr4B_48640851_T / C,Chr4B_48640937_A / C,Chr4B_48640945_G / C,Chr4B_48640983_C / G,Chr4B_48641126_A / G,Chr4B_48641147_T / C,Chr4B_48641199_C / T,Chr4B_48641325_A / C,Chr4B_48641328_A / G,Chr4B_48641338_C / T,Chr4B_48641388_T / C,Chr4B_48641450_C / T,Chr4B_48641575_G / A,Chr4B_48641610_T / C,Chr4B_48641683_C / A,Chr4B_48641688_C / T,Chr4B_48641758_C / A,Chr4B_48641761_G / C,Chr4B_48641803_G / A,Chr4B_48641925_T / A,Chr4B_48641941_T / A,Chr4B_48641947_C / T,Chr4B_48642035_A / G,Chr4B_48642045_A / T,Chr4B_48642046_C / T,Chr4B_48642783_A / G,Chr4B_48642841_T / C,Chr4B_48642842_G / A,Chr4B_48642931_A / T,Chr4B_48642985_T / C,Chr4B_48643139_C / T,Chr4B_48643147_C / T,Chr4B_48643173_T / C,Chr4B_48643336_C / T,Chr4B_48643524_T / C,Chr4B_48643637_G / A,Chr4B_48643653_C / T,Chr4B_48643892_T / G,Chr4B_48644094_T / A,Chr4B_48644138_A / G,Chr4B_48644154_G / A,Chr4B_48644161_C / A,Chr4B_48644395_C / T,Chr4B_48644594_T / C,Chr4B_48644599_C / T,Chr4B_48644734_C / T,Chr4B_48645013_T / C,Chr4B_48645077_G / A,Chr4B_48645246_T / A,Chr4B_48645364_A / G,Chr4B_48645629_A / G,Chr4B_48645681_T / C,Chr4B_48645734_C / T,Chr4B_48646017_A / G,Chr4B_48646072_G / C,Chr4B_48646531_G / C,Chr4B_48646542_G / A,Chr4B_48647959_G / A,Chr4B_48648124_T / A,Chr4B_48648594_A / T,Chr4B_48648744_A / T,Chr4B_48648761_G / C,Chr4B_48648771_G / A,Chr4B_48648786_G / A,Chr4B_48648890_C / T,Chr4B_48649080_T / A,Chr4B_48649134_C / A,Chr4B_48649335_C / A,Chr4B_48649350_A / G,Chr4B_48649374_A / G,Chr4B_48649431_T / C,Chr4B_48649434_C / T,Chr4B_48649472_C / A,Chr4B_48649569_G / A,Chr4B_48649575_G / A,Chr4B_48649690_C / G,Chr4B_48649933_T / C,Chr4B_48650095_T / C,Chr4B_48650099_C / T,Chr4B_48650213_A / T,Chr4B_48650281_T / A,Chr4B_48650314_A / G,Chr4B_48650329_A / G,Chr4B_48650335_A / T,Chr4B_48650405_T / C,Chr4B_48650451_C / T,Chr4B_48650454_A / G,Chr4B_48650476_G / T,Chr4B_48650513_A / C,Chr4B_48650715_T / G,Chr4B_48650934_G / C,Chr4B_48651019_C / T,Chr4B_48651048_A / G,Chr4B_48651054_C / G,Chr4B_48651148_C / T,Chr4B_48651158_C / G,Chr4B_48651279_G / C,Chr4B_48651387_C / A,Chr4B_48651415_G / C,Chr4B_48651528_G / A,Chr4B_48651598_C / T,Chr4B_48651728_T / G,Chr4B_48651751_T / C,Chr4B_48651761_T / C,Chr4B_48651785_A / T,Chr4B_48651842_A / C,Chr4B_48652035_A / T,Chr4B_48652055_A / T,Chr4B_48652080_T / C,Chr4B_48652141_T / A,Chr4B_48652201_T / C,Chr4B_48652291_T / A,Chr4B_48652350_A / T,Chr4B_48652378_A / G,Chr4B_48652389_C / T,Chr4B_48652570_T / A,Chr4B_48652699_T / C,Chr4B_48652711_T / C,Chr4B_48652727_A / G,Chr4B_48652955_C / G,Chr4B_48653052_A / C,Chr4B_48653335_A / G,Chr4B_48653412_T / C,Chr4B_48653456_A / G,Chr4B_48653535_A / G,Chr4B_48653586_C / T,Chr4B_48653795_T / A,Chr4B_48653797_T / G,Chr4B_48654024_T / A,Chr4B_48654183_G / C,Chr4B_48654208_T / C,Chr4B_48654246_G / T,Chr4B_48654302_C / T,Chr4B_48654501_T / A,Chr4B_48654565_T / A,Chr4B_48654668_C / G,Chr4B_48654698_A / G,Chr4B_48654704_G / A,Chr4B_48654751_C / T,Chr4B_48654765_A / G,Chr4B_48654781_C / T,Chr4B_48654869_C / T,Chr4B_48655593_C / T,Chr4B_48655693_A / G,Chr4B_48655933_C / T,Chr4B_48655938_C / A,Chr4B_48656007_C / G,Chr4B_48656019_T / C,Chr4B_48656106_C / T,Chr4B_48656116_G / C,Chr4B_48656147_T / C,Chr4B_48656202_G / A,Chr4B_48656248_C / T,Chr4B_48656379_G / C,Chr4B_48656433_T / C,Chr4B_48657076_C / T,Chr4B_48657339_C / G,Chr4B_48657419_C / A,Chr4B_48657433_T / C,Chr4B_48657494_T / C,Chr4B_48657612_T / C,Chr4B_48657730_A / C,Chr4B_48657833_G / A,Chr4B_48657867_G / T,Chr4B_48657894_T / A,Chr4B_48658367_T / A,Chr4B_48658372_C / T,Chr4B_48658525_G / A,Chr4B_48658532_T / A,Chr4B_48658625_G / A,Chr4B_48658687_T / G,Chr4B_48658772_T / A,Chr4B_48658952_T / C,Chr4B_48659066_G / C,Chr4B_48659114_G / A,Chr4B_48659167_G / A,Chr4B_48659355_C / T,Chr4B_48659749_T / C,Chr4B_48659760_C / T,Chr4B_48659808_G / A,Chr4B_48659878_T / C,Chr4B_48659924_C / G,Chr4B_48660116_T / C,Chr4B_48660133_T / C,Chr4B_48660145_G / A,Chr4B_48660188_G / A,Chr4B_48660252_C / T,Chr4B_48660260_A / T,Chr4B_48660263_C / T,Chr4B_48660271_C / T,Chr4B_48660272_A / G,Chr4B_48660302_T / G,Chr4B_48660425_T / C,Chr4B_48660813_G / A,Chr4B_48660819_A / C,Chr4B_48660821_G / T,Chr4B_48660826_A / G,Chr4B_48660854_T / A,Chr4B_48661062_T / A,Chr4B_48661203_C / A,Chr4B_48661310_C / A,Chr4B_48661372_G / C,Chr4B_48661384_G / A,Chr4B_48661432_T / C,Chr4B_48661441_A / G,Chr4B_48661444_T / C,Chr4B_48661586_A / T,Chr4B_48661630_G / A,Chr4B_48661731_A / G,Chr4B_48661753_C / A,Chr4B_48661793_C / T,Chr4B_48662016_C / T,Chr4B_48662045_A / T,Chr4B_48662048_A / G,Chr4B_48662450_T / G,Chr4B_48662457_T / C,Chr4B_48662495_C / T,Chr4B_48662558_T / A,Chr4B_48662610_A / G,Chr4B_48662730_C / T,Chr4B_48663112_T / A,Chr4B_48663120_A / G,Chr4B_48663256_T / A,Chr4B_48663541_T / A,Chr4B_48666222_T / A,Chr4B_48666280_T / G,Chr4B_48666445_T / C,Chr4B_48666450_A / G,Chr4B_48666503_C / T,Chr4B_48667129_T / C,Chr4B_48667131_C / T,Chr4B_48668263_T / G,Chr4B_48668335_A / G,Chr4B_48668383_C / A,Chr4B_48668945_T / C,Chr4B_48669026_C / T,Chr4B_48669087_T / A,Chr4B_48669105_C / T,Chr4B_48669761_T / C,Chr4B_48669779_T / A,Chr4B_48669781_G / A,Chr4B_48670063_T / A,Chr4B_48670065_C / T,Chr4B_48670084_G / A,Chr4B_48670167_A / T,Chr4B_48670184_C / T,Chr4B_48670188_C / G,Chr4B_48670263_T / A,Chr4B_48670438_A / G,Chr4B_48670440_G / A,Chr4B_48670473_G / A,Chr4B_48670490_A / G,Chr4B_48670630_C / T,Chr4B_48670740_A / T,Chr4B_48670744_T / A,Chr4B_48670746_T / C,Chr4B_48670761_G / C,Chr4B_48670859_T / C,Chr4B_48670910_T / A,Chr4B_48670929_A / T,Chr4B_48671007_A / G,Chr4B_48671036_C / G,Chr4B_48671072_G / T,Chr4B_48671160_A / C,Chr4B_48671237_C / T,Chr4B_48671308_T / A,Chr4B_48671312_C / T,Chr4B_48671424_A / C,Chr4B_48671488_G / A,Chr4B_48671501_T / C,Chr4B_48671510_C / A,Chr4B_48671513_A / T,Chr4B_48671587_C / T,Chr4B_48671667_G / A,Chr4B_48671789_C / A,Chr4B_48671790_C / T,Chr4B_48671814_C / A,Chr4B_48671949_A / G,Chr4B_48671956_T / C,Chr4B_48671963_C / T,Chr4B_48672076_A / G,Chr4B_48672160_A / T,Chr4B_48672165_A / C,Chr4B_48672177_T / G,Chr4B_48672185_C / A,Chr4B_48672205_T / A,Chr4B_48672321_A / C,Chr4B_48672389_C / T,Chr4B_48672499_C / A,Chr4B_48672617_C / T,Chr4B_48672674_T / G,Chr4B_48672704_C / T,Chr4B_48672758_T / C,Chr4B_48672803_T / C,Chr4B_48673322_T / G,Chr4B_48673323_T / C,Chr4B_48673496_T / A,Chr4B_48673548_T / C,Chr4B_48673603_G / C,Chr4B_48673641_A / G,Chr4B_48673644_A / T,Chr4B_48673710_T / C,Chr4B_48673929_A / C,Chr4B_48673937_G / T,Chr4B_48673940_A / T,Chr4B_48674182_T / G,Chr4B_48674533_A / G,Chr4B_48674707_C / T,Chr4B_48674851_T / A,Chr4B_48675032_C / A,Chr4B_48675057_A / G,Chr4B_48675143_G / A,Chr4B_48675161_T / A,Chr4B_48675186_C / A,Chr4B_48675196_A / G,Chr4B_48677105_C / T,Chr4B_48677138_G / A,Chr4B_48677276_C / T,Chr4B_48677282_T / C,Chr4B_48677455_T / C,Chr4B_48677456_A / G,Chr4B_48677470_C / A,Chr4B_48677481_T / A,Chr4B_48677483_A / T,Chr4B_48677504_A / C,Chr4B_48677793_A / C,Chr4B_48677817_T / C,Chr4B_48678110_A / C,Chr4B_48678133_G / C,Chr4B_48678181_A / G,Chr4B_48678254_T / C,Chr4B_48678280_T / A,Chr4B_48678633_A / G,Chr4B_48678691_A / G,Chr4B_48691911_G / T,Chr4B_48691915_C / G,Chr4B_48691925_A / C,Chr4B_48692023_A / G,Chr4B_48692043_G / T,Chr4B_48692099_C / A,Chr4B_48692258_A / T,Chr4B_48692327_T / A,Chr4B_48692876_C / A,Chr4B_48692927_A / G,Chr4B_48693012_A / G,Chr4B_48693068_G / A,Chr4B_48693086_T / C,Chr4B_48693232_G / C,Chr4B_48693240_C / T,Chr4B_48693242_A / G,Chr4B_48693313_T / A,Chr4B_48704393_A / C,Chr4B_48704454_A / C,Chr4B_48704597_T / G,Chr4B_48704847_T / G,Chr4B_48704977_G / A,Chr4B_48704993_G / C,Chr4B_48705438_C / T,Chr4B_48705446_A / G,Chr4B_48705454_C / T,Chr4B_48705545_A / G,Chr4B_48705641_A / G,Chr4B_48705656_G / A,Chr4B_48705657_G / C,Chr4B_48705711_T / A,Chr4B_48705850_A / G,Chr4B_48705926_A / G,Chr4B_48706007_T / C,Chr4B_48706032_A / T,Chr4B_48706043_A / G,Chr4B_48706069_A / C,Chr4B_48706080_T / C,Chr4B_48706282_G / A,Chr4B_48706283_T / C,Chr4B_48706291_A / G,Chr4B_48706382_T / C,Chr4B_48706383_G / A,Chr4B_48706406_G / A,Chr4B_48706409_C / A,Chr4B_48706413_A / G,Chr4B_48706450_A / G,Chr4B_48706598_C / A,Chr4B_48706607_C / A,Chr4B_48706654_T / A,Chr4B_48706717_C / G,Chr4B_48706726_G / A,Chr4B_48706738_C / A,Chr4B_48706741_G / A,Chr4B_48706806_T / C,Chr4B_48706923_C / T,Chr4B_48706954_A / G,Chr4B_48707204_C / A,Chr4B_48707331_C / G,Chr4B_48707461_C / T,Chr4B_48709453_G / A,Chr4B_48709555_C / T,Chr4B_48709563_G / T,Chr4B_48709591_G / C,Chr4B_48709622_C / A,Chr4B_48709630_A / G,Chr4B_48710034_C / G,Chr4B_48710035_T / C,Chr4B_48710187_A / G,Chr4B_48710207_T / G,Chr4B_48710230_T / A,Chr4B_48710397_C / G,Chr4B_48710493_A / G,Chr4B_48711079_C / T,Chr4B_48711109_C / G,Chr4B_48711133_T / A,Chr4B_48711162_T / C,Chr4B_48711170_A / G,Chr4B_48711247_T / C,Chr4B_48711332_C / A,Chr4B_48711494_T / A,Chr4B_48712326_C / G,Chr4B_48712367_C / T,Chr4B_48712624_G / C,Chr4B_48712629_G / A,Chr4B_48712767_C / T,Chr4B_48713086_C / G,Chr4B_48713170_T / A,Chr4B_48713427_C / A,Chr4B_48713673_G / A,Chr4B_48713677_A / T,Chr4B_48714007_C / A,Chr4B_48714129_C / A,Chr4B_48714343_A / T,Chr4B_48716256_A / G,Chr4B_48716517_G / T,Chr4B_48716579_C / T,Chr4B_48716606_A / G,Chr4B_48716607_T / G,Chr4B_48716609_G / C,Chr4B_48716613_G / T,Chr4B_48716632_A / G,Chr4B_48716681_C / T,Chr4B_48716684_C / T,Chr4B_48716687_C / A,Chr4B_48716692_A / G,Chr4B_48716809_T / A,Chr4B_48717085_A / G,Chr4B_48717104_T / G,Chr4B_48717150_C / G,Chr4B_48717157_T / G,Chr4B_48718317_T / C,Chr4B_48718325_T / A,Chr4B_48718334_G / T,Chr4B_48718403_T / G,Chr4B_48718420_C / A,Chr4B_48718442_A / G,Chr4B_48719195_T / A,Chr4B_48719240_G / A,Chr4B_48719281_C / T,Chr4B_48719324_T / A,Chr4B_48719466_C / T,Chr4B_48719487_C / T,Chr4B_48719550_G / T,Chr4B_48719626_C / T,Chr4B_48719635_T / A,Chr4B_48719762_G / A,Chr4B_48719778_C / G,Chr4B_48719895_T / G,Chr4B_48720045_C / A,Chr4B_48720080_C / T,Chr4B_48720100_C / A,Chr4B_48720170_A / G,Chr4B_48720324_C / G,Chr4B_48720362_A / G,Chr4B_48720422_C / A,Chr4B_48720433_T / G,Chr4B_48720462_G / A,Chr4B_48720580_C / T,Chr4B_48720684_A / C,Chr4B_48720758_A / C,Chr4B_48720903_C / T,Chr4B_48720960_A / G,Chr4B_48721159_A / G,Chr4B_48721296_C / A,Chr4B_48721501_A / G,Chr4B_48721556_T / G,Chr4B_48721600_G / T,Chr4B_48721623_A / G,Chr4B_48721840_C / G,Chr4B_48721875_A / G,Chr4B_48721957_T / C,Chr4B_48721961_T / C,Chr4B_48722177_A / C,Chr4B_48722194_A / C,Chr4B_48722214_A / G,Chr4B_48722231_T / A,Chr4B_48722357_T / A,Chr4B_48722481_T / C,Chr4B_48722550_C / G,Chr4B_48722601_T / C,Chr4B_48722664_A / G,Chr4B_48722673_A / G,Chr4B_48722733_G / C,Chr4B_48722745_A / G,Chr4B_48722769_A / G,Chr4B_48722838_A / G,Chr4B_48722994_T / A,Chr4B_48723136_A / G,Chr4B_48723179_C / G,Chr4B_48723558_T / A,Chr4B_48723908_C / A,Chr4B_48724320_G / A,Chr4B_48724512_G / A,Chr4B_48724608_G / A,Chr4B_48724681_T / A,Chr4B_48724790_G / T,Chr4B_48730608_C / T,Chr4B_48730610_C / G,Chr4B_48730628_T / A,Chr4B_48731196_T / G,Chr4B_48731212_T / A,Chr4B_48731215_C / T,Chr4B_48734721_G / C,Chr4B_48734761_C / T,Chr4B_48734833_C / A,Chr4B_48751318_T / C,Chr4B_48751500_A / G,Chr4B_48751683_A / T,Chr4B_48751734_T / G,Chr4B_48751881_G / T,Chr4B_48751909_A / G,Chr4B_48751923_T / A,Chr4B_48751933_G / A,Chr4B_48751963_A / G,Chr4B_48752005_T / C,Chr4B_48752021_T / C,Chr4B_48752023_C / T,Chr4B_48752051_G / A,Chr4B_48752144_A / T,Chr4B_48752156_G / A,Chr4B_48752208_G / C,Chr4B_48752225_T / C,Chr4B_48752466_T / C,Chr4B_48752905_G / C,Chr4B_48752979_G / T,Chr4B_48753123_G / T,Chr4B_48753486_A / G,Chr4B_48755487_T / C,Chr4B_48755489_T / C,Chr4B_48755611_A / G,Chr4B_48755613_T / C,Chr4B_48755735_C / T,Chr4B_48755758_T / C,Chr4B_48755796_C / A,Chr4B_48755799_C / T,Chr4B_48755806_T / C,Chr4B_48755825_G / C,Chr4B_48755938_G / A,Chr4B_48756022_C / T,Chr4B_48756037_T / C,Chr4B_48756044_A / C,Chr4B_48756194_A / G,Chr4B_48756199_C / A,Chr4B_48756340_C / T,Chr4B_48756408_G / A,Chr4B_48756434_G / C,Chr4B_48756436_G / A,Chr4B_48756467_T / A,Chr4B_48756598_A / C,Chr4B_48756604_A / G,Chr4B_48756617_A / G,Chr4B_48756706_A / C,Chr4B_48756823_T / G,Chr4B_48756924_A / T,Chr4B_48757005_T / C,Chr4B_48757285_A / T,Chr4B_48757329_C / G,Chr4B_48757716_A / G,Chr4B_48758076_C / G,Chr4B_48758081_C / T,Chr4B_48758241_C / T,Chr4B_48758381_C / T,Chr4B_48758477_G / A,Chr4B_48758498_C / T,Chr4B_48758609_T / G,Chr4B_48758638_T / C,Chr4B_48758933_C / G,Chr4B_48759098_C / G,Chr4B_48759109_T / C,Chr4B_48759182_C / A,Chr4B_48759229_T / A,Chr4B_48759235_C / T,Chr4B_48759256_T / C,Chr4B_48759291_T / G,Chr4B_48759491_C / T,Chr4B_48759540_A / G,Chr4B_48759555_T / G,Chr4B_48759557_A / G,Chr4B_48759573_A / G,Chr4B_48759574_A / T,Chr4B_48759606_G / T,Chr4B_48759635_G / A,Chr4B_48759759_A / G,Chr4B_48759789_G / T,Chr4B_48759875_T / C,Chr4B_48759968_G / C,Chr4B_48759969_G / C,Chr4B_48759973_A / G,Chr4B_48759974_C / A,Chr4B_48760011_T / C,Chr4B_48760117_T / C,Chr4B_48760191_C / G,Chr4B_48760277_G / T,Chr4B_48760279_T / A,Chr4B_48760414_T / A,Chr4B_48760415_A / T,Chr4B_48760461_T / C,Chr4B_48760471_G / A,Chr4B_48760487_C / T,Chr4B_48760534_T / G,Chr4B_48760546_G / A,Chr4B_48760560_A / G,Chr4B_48760694_T / A,Chr4B_48760723_T / A,Chr4B_48760743_C / A,Chr4B_48760753_T / A,Chr4B_48760795_G / A,Chr4B_48760842_T / C,Chr4B_48761011_A / G,Chr4B_48761151_G / A,Chr4B_48761354_T / A,Chr4B_48761395_G / A,Chr4B_48761398_A / G,Chr4B_48761419_A / T,Chr4B_48761458_G / T,Chr4B_48761886_C / T,Chr4B_48761937_A / T,Chr4B_48761957_C / T,Chr4B_48761982_A / T,Chr4B_48761984_T / G,Chr4B_48762056_A / T,Chr4B_48762105_G / T,Chr4B_48762236_C / A,Chr4B_48762237_A / G,Chr4B_48762320_G / C,Chr4B_48762434_G / C,Chr4B_48762671_T / C,Chr4B_48762672_G / C,Chr4B_48762731_G / A,Chr4B_48762783_C / T,Chr4B_48762790_A / G,Chr4B_48762813_T / C,Chr4B_48762884_A / T,Chr4B_48776121_T / G,Chr4B_48776138_G / A,Chr4B_48776276_C / G,Chr4B_48776279_G / T,Chr4B_48776282_A / G,Chr4B_48776442_C / T,Chr4B_48776450_T / A,Chr4B_48776462_G / A,Chr4B_48776489_A / T,Chr4B_48776494_C / T,Chr4B_48776526_C / T,Chr4B_48776558_T / A,Chr4B_48776578_C / T,Chr4B_48776641_T / C,Chr4B_48776668_G / A,Chr4B_48776680_A / T,Chr4B_48776682_A / G,Chr4B_48776691_G / T,Chr4B_48776693_A / G,Chr4B_48776806_A / T,Chr4B_48776818_G / T,Chr4B_48776941_C / T,Chr4B_48776957_T / C,Chr4B_48776969_A / G,Chr4B_48777010_T / G,Chr4B_48777030_A / C,Chr4B_48777115_T / C,Chr4B_48777125_C / T,Chr4B_48777144_C / T,Chr4B_48777158_A / C,Chr4B_48777176_G / A,Chr4B_48777190_T / C,Chr4B_48777211_A / G,Chr4B_48777256_G / A,Chr4B_48777260_A / G,Chr4B_48777375_A / C,Chr4B_48777448_T / A,Chr4B_48777469_C / T,Chr4B_48777490_T / A,Chr4B_48777494_A / C,Chr4B_48779997_C / T,Chr4B_48780075_G / A,Chr4B_48780078_C / T,Chr4B_48780098_A / C,Chr4B_48780102_A / G,Chr4B_48780104_C / G,Chr4B_48780116_C / T,Chr4B_48780129_A / T,Chr4B_48780156_G / A,Chr4B_48780163_G / A,Chr4B_48780184_G / T,Chr4B_48780206_A / C,Chr4B_48780213_C / T,Chr4B_48780220_G / T,Chr4B_48780251_C / T,Chr4B_48780254_T / C,Chr4B_48780264_C / T,Chr4B_48780271_G / T,Chr4B_48780316_C / T,Chr4B_48780357_T / A,Chr4B_48780382_C / T,Chr4B_48780405_T / A,Chr4B_48780487_C / T,Chr4B_48780502_T / G,Chr4B_48780504_C / A,Chr4B_48780518_G / A,Chr4B_48780641_G / A,Chr4B_48780651_A / G,Chr4B_48780743_A / C,Chr4B_48780778_G / A,Chr4B_48782116_A / G,Chr4B_48782121_T / C,Chr4B_48782219_T / C,Chr4B_48782745_C / A,Chr4B_48782760_C / T,Chr4B_48783115_A / G,Chr4B_48783134_T / C,Chr4B_48783145_T / C,Chr4B_48783156_A / C,Chr4B_48783250_A / G,Chr4B_48783273_G / C,Chr4B_48783311_C / T,Chr4B_48783319_A / G,Chr4B_48783407_T / G,Chr4B_48783544_C / T,Chr4B_48783576_A / G,Chr4B_48783579_G / A,Chr4B_48784214_T / A,Chr4B_48784217_T / G,Chr4B_48784355_A / C,Chr4B_48784422_G / A,Chr4B_48784426_G / A,Chr4B_48784763_T / C,Chr4B_48784883_T / A,Chr4B_48787834_G / A,Chr4B_48787843_A / G,Chr4B_48787854_G / A,Chr4B_48787899_G / T,Chr4B_48787948_A / T,Chr4B_48787979_C / T,Chr4B_48787990_T / A,Chr4B_48789472_T / C,Chr4B_48789500_G / A,Chr4B_48789514_G / T,Chr4B_48789576_T / C,Chr4B_48789617_G / A,Chr4B_48789628_G / A,Chr4B_48789657_C / T,Chr4B_48789662_G / T,Chr4B_48789695_A / G,Chr4B_48789732_A / T,Chr4B_48790626_T / G,Chr4B_48790633_A / G,Chr4B_48790719_G / A,Chr4B_48790720_A / G,Chr4B_48790817_T / C,Chr4B_48790880_T / A,Chr4B_48790901_T / C,Chr4B_48790907_T / C,Chr4B_48791146_T / G,Chr4B_48791302_T / G,Chr4B_48791304_G / T,Chr4B_48791621_G / A,Chr4B_48791631_A / G,Chr4B_48791655_C / A,Chr4B_48791709_G / A,Chr4B_48791718_T / C,Chr4B_48791816_C / T,Chr4B_48791872_T / C,Chr4B_48792195_G / A,Chr4B_48792198_C / A,Chr4B_48792205_C / A,Chr4B_48792344_A / T,Chr4B_48792357_G / A,Chr4B_48792372_C / T,Chr4B_48792439_T / C,Chr4B_48792461_T / G,Chr4B_48792737_C / G,Chr4B_48792741_T / C,Chr4B_48792745_A / G,Chr4B_48793027_T / C,Chr4B_48793136_C / T,Chr4B_48793138_C / T,Chr4B_48793405_G / A,Chr4B_48793421_C / A,Chr4B_48793422_G / A,Chr4B_48793432_G / T,Chr4B_48793445_C / A,Chr4B_48793489_G / A,Chr4B_48793603_G / A,Chr4B_48793614_T / C,Chr4B_48793686_C / A,Chr4B_48794023_C / T,Chr4B_48794066_C / T,Chr4B_48794208_A / C,Chr4B_48794260_C / T,Chr4B_48794414_T / C,Chr4B_48794710_G / A,Chr4B_48794788_C / G,Chr4B_48794799_A / C,Chr4B_48794968_C / T,Chr4B_48795084_A / C,Chr4B_48795226_A / C,Chr4B_48795506_G / A,Chr4B_48795518_A / G,Chr4B_48795569_C / A,Chr4B_48795584_T / C,Chr4B_48795588_A / T,Chr4B_48797495_C / G,Chr4B_48797506_G / A,Chr4B_48797601_T / C,Chr4B_48799678_G / C,Chr4B_48799772_A / G,Chr4B_48799804_T / C,Chr4B_48799818_C / T,Chr4B_48799850_C / T,Chr4B_48799930_A / T,Chr4B_48799967_C / T,Chr4B_48799987_G / T,Chr4B_48800026_T / C,Chr4B_48800115_T / C,Chr4B_48800243_T / C,Chr4B_48800278_T / C,Chr4B_48800288_T / A,Chr4B_48800562_T / G,Chr4B_48800658_G / T,Chr4B_48801032_A / G,Chr4B_48801192_A / T,Chr4B_48801193_A / C,Chr4B_48801246_T / A,Chr4B_48801446_C / T,Chr4B_48801540_T / A,Chr4B_48801591_T / A,Chr4B_48801729_G / A,Chr4B_48802541_C / T,Chr4B_48802547_C / T,Chr4B_48802556_C / T,Chr4B_48802641_A / G,Chr4B_48802734_A / G,Chr4B_48803011_C / T,Chr4B_48803058_G / A,Chr4B_48803079_G / A,Chr4B_48803106_A / G,Chr4B_48803107_A / G,Chr4B_48803232_C / A,Chr4B_48803288_G / A,Chr4B_48803682_G / A,Chr4B_48804060_C / T,Chr4B_48804303_T / C,Chr4B_48804372_A / G,Chr4B_48804558_T / A,Chr4B_48804752_C / A,Chr4B_48804887_A / G,Chr4B_48804936_G / A,Chr4B_48805113_C / T,Chr4B_48805139_G / C,Chr4B_48805142_A / C,Chr4B_48805183_T / A,Chr4B_48807481_G / C,Chr4B_48807510_G / A,Chr4B_48807562_G / A,Chr4B_48807637_C / T,Chr4B_48807822_A / T,Chr4B_48808375_C / T,Chr4B_48808380_C / T,Chr4B_48808516_C / A,Chr4B_48808525_C / G,Chr4B_48808534_G / T,Chr4B_48808566_G / C,Chr4B_48808624_C / G,Chr4B_48808685_T / C,Chr4B_48808699_T / G,Chr4B_48808700_C / G,Chr4B_48808701_T / C,Chr4B_48808712_T / C,Chr4B_48810404_C / A,Chr4B_48810482_C / A,Chr4B_48810487_A / G,Chr4B_48813151_C / T,Chr4B_48813261_A / G,Chr4B_48813505_G / C,Chr4B_48816022_C / A,Chr4B_48816037_G / A,Chr4B_48816070_C / T,Chr4B_48816073_A / G,Chr4B_48816092_T / C,Chr4B_48816106_C / T,Chr4B_48816108_T / G,Chr4B_48816252_C / T,Chr4B_48816267_T / C,Chr4B_48816398_T / C,Chr4B_48816406_T / C,Chr4B_48816469_T / C,Chr4B_48816578_A / G,Chr4B_48816681_C / A,Chr4B_48816709_C / T,Chr4B_48817010_G / T,Chr4B_48817425_C / G,Chr4B_48817589_T / C,Chr4B_48817600_G / A,Chr4B_48817625_C / A,Chr4B_48817677_G / A,Chr4B_48817811_A / G,Chr4B_48818156_T / C,Chr4B_48818285_C / T,Chr4B_48818334_A / T,Chr4B_48818408_C / T,Chr4B_48822370_G / T,Chr4B_48822549_G / A,Chr4B_48822552_T / A,Chr4B_48822578_G / A,Chr4B_48822636_C / A,Chr4B_48822666_T / A,Chr4B_48822741_G / A,Chr4B_48822764_G / C,Chr4B_48822793_T / C,Chr4B_48822858_G / C,Chr4B_48822908_A / G,Chr4B_48822969_C / T,Chr4B_48822974_A / G,Chr4B_48822982_A / T,Chr4B_48822986_T / C,Chr4B_48823020_A / C,Chr4B_48823043_A / C,Chr4B_48823143_C / G,Chr4B_48823147_C / T,Chr4B_48823203_A / T,Chr4B_48823214_C / G,Chr4B_48823248_A / C,Chr4B_48823253_C / G,Chr4B_48823261_T / G,Chr4B_48823304_T / A,Chr4B_48823307_A / C,Chr4B_48823378_A / G,Chr4B_48823403_C / A,Chr4B_48823421_G / C,Chr4B_48823437_G / A,Chr4B_48823466_A / C,Chr4B_48823533_A / G,Chr4B_48823567_T / G,Chr4B_48823573_T / A,Chr4B_48823616_G / A,Chr4B_48823622_G / A,Chr4B_48823663_C / G,Chr4B_48823678_T / A,Chr4B_48823696_G / C,Chr4B_48823697_C / T,Chr4B_48823705_C / A,Chr4B_48823734_T / A,Chr4B_48823746_A / T,Chr4B_48823751_T / A,Chr4B_48823766_G / C,Chr4B_48823790_G / A,Chr4B_48823796_G / A,Chr4B_48823797_G / A,Chr4B_48823906_A / G,Chr4B_48823907_C / T,Chr4B_48823923_T / A,Chr4B_48823956_G / T,Chr4B_48823988_C / T,Chr4B_48824006_A / G,Chr4B_48824027_C / T,Chr4B_48824096_C / G,Chr4B_48824133_C / T,Chr4B_48824146_T / C,Chr4B_48824170_C / G,Chr4B_48824203_A / C,Chr4B_48824215_G / C,Chr4B_48824231_T / C,Chr4B_48824244_A / C,Chr4B_48824354_A / G,Chr4B_48830486_T / C,Chr4B_48830583_G / T,Chr4B_48830603_G / C,Chr4B_48830828_T / G,Chr4B_48830829_G / A,Chr4B_48830863_A / C,Chr4B_48830869_T / G,Chr4B_48830996_T / C,Chr4B_48832524_A / G,Chr4B_48832614_C / G,Chr4B_48832617_A / T,Chr4B_48832639_A / T,Chr4B_48832648_C / T,Chr4B_48832649_T / C,Chr4B_48832731_G / T,Chr4B_48832735_C / A,Chr4B_48832780_C / A,Chr4B_48832790_G / A,Chr4B_48832878_A / T,Chr4B_48832917_G / C,Chr4B_48832926_G / T,Chr4B_48832933_T / A,Chr4B_48833000_C / T,Chr4B_48833210_T / A,Chr4B_48833216_A / G,Chr4B_48833270_A / G,Chr4B_48833351_C / A,Chr4B_48833361_T / G,Chr4B_48833394_G / A,Chr4B_48833537_G / A,Chr4B_48833554_G / A,Chr4B_48833569_T / C,Chr4B_48833607_A / G,Chr4B_48833612_A / G,Chr4B_48833651_A / G,Chr4B_48833655_G / A,Chr4B_48833711_G / C,Chr4B_48833741_A / G,Chr4B_48833774_G / A,Chr4B_48833779_A / G,Chr4B_48833799_G / A,Chr4B_48833809_A / T,Chr4B_48833816_T / C,Chr4B_48833817_T / C,Chr4B_48833827_A / G,Chr4B_48833881_C / T,Chr4B_48833968_C / T,Chr4B_48834070_C / A,Chr4B_48834481_T / G,Chr4B_48834617_A / G,Chr4B_48835168_A / C,Chr4B_48835197_A / G,Chr4B_48835242_T / C,Chr4B_48835256_T / A,Chr4B_48835719_A / T,Chr4B_48835873_G / T,Chr4B_48836540_T / G,Chr4B_48836589_A / T,Chr4B_48836783_T / A,Chr4B_48836787_T / A,Chr4B_48836789_G / A,Chr4B_48837210_A / G,Chr4B_48837358_T / A,Chr4B_48837371_C / A,Chr4B_48837562_A / G,Chr4B_48837565_G / A,Chr4B_48837590_T / C,Chr4B_48837651_A / G,Chr4B_48837686_A / G,Chr4B_48837708_G / A,Chr4B_48837723_T / C,Chr4B_48837832_G / A,Chr4B_48837835_G / A,Chr4B_48837843_C / T,Chr4B_48837965_C / T,Chr4B_48837983_A / G,Chr4B_48837984_C / T,Chr4B_48837987_C / T,Chr4B_48837995_G / A,Chr4B_48837998_G / A,Chr4B_48838002_T / C,Chr4B_48838011_C / T,Chr4B_48838108_G / A,Chr4B_48838130_T / C,Chr4B_48838366_A / T,Chr4B_48838381_T / A,Chr4B_48840223_T / A,Chr4B_48840278_A / T,Chr4B_48840307_G / T,Chr4B_48840321_G / A,Chr4B_48840327_C / T,Chr4B_48840331_T / G,Chr4B_48840354_A / T,Chr4B_48840362_A / T,Chr4B_48840444_T / C,Chr4B_48840511_G / A,Chr4B_48840652_A / G,Chr4B_48840795_G / C,Chr4B_48840811_G / A,Chr4B_48840872_G / A,Chr4B_48840891_C / T,Chr4B_48841119_C / T,Chr4B_48841144_T / A,Chr4B_48841206_C / A,Chr4B_48841250_C / T,Chr4B_48841324_A / T,Chr4B_48841328_A / G,Chr4B_48841330_A / G,Chr4B_48841332_A / G,Chr4B_48841341_A / G,Chr4B_48841345_A / G,Chr4B_48841355_C / T,Chr4B_48841360_A / T,Chr4B_48841402_C / T,Chr4B_48841404_G / T,Chr4B_48841439_A / G,Chr4B_48841566_C / A,Chr4B_48841660_T / G,Chr4B_48841675_A / G,Chr4B_48841714_G / A,Chr4B_48841776_T / C,Chr4B_48841825_A / T,Chr4B_48841832_G / C,Chr4B_48841912_G / A,Chr4B_48841992_G / T,Chr4B_48842026_C / A,Chr4B_48842217_T / A,Chr4B_48842226_T / C,Chr4B_48842428_T / C,Chr4B_48842537_A / T,Chr4B_48842612_T / G,Chr4B_48842709_T / C,Chr4B_48842785_G / A,Chr4B_48842915_G / T,Chr4B_48843023_G / A,Chr4B_48843199_T / C,Chr4B_48843229_G / A,Chr4B_48843367_T / C,Chr4B_48843430_T / G,Chr4B_48843464_C / A,Chr4B_48843578_G / C,Chr4B_48843589_G / A,Chr4B_48843743_C / G,Chr4B_48844035_T / C,Chr4B_48844039_T / A,Chr4B_48844045_T / C,Chr4B_48844047_G / C,Chr4B_48844112_A / G,Chr4B_48844129_C / T,Chr4B_48844163_C / T,Chr4B_48844174_A / G,Chr4B_48844175_G / A,Chr4B_48844223_C / T,Chr4B_48844224_G / T,Chr4B_48844239_G / T,Chr4B_48844279_A / G,Chr4B_48844299_G / A,Chr4B_48844313_C / G,Chr4B_48844351_G / T,Chr4B_48844356_C / T,Chr4B_48844384_T / C,Chr4B_48844450_G / A,Chr4B_48844463_G / A,Chr4B_48844481_A / T,Chr4B_48844486_A / C,Chr4B_48844487_T / A,Chr4B_48844516_A / G,Chr4B_48844523_C / T,Chr4B_48844545_G / A,Chr4B_48844625_C / T,Chr4B_48844635_C / A,Chr4B_48854940_A / G,Chr4B_48854948_C / T,Chr4B_48856149_C / A,Chr4B_48856232_A / G,Chr4B_48856260_G / T,Chr4B_48856323_T / C,Chr4B_48856353_C / T,Chr4B_48856424_G / A,Chr4B_48856433_A / C,Chr4B_48856598_A / G,Chr4B_48856665_T / A,Chr4B_48857023_T / C,Chr4B_48857125_T / C,Chr4B_48857276_G / T,Chr4B_48858228_C / T,Chr4B_48858257_T / C,Chr4B_48858371_G / T,Chr4B_48858497_T / A,Chr4B_48858503_T / A,Chr4B_48858521_T / A,Chr4B_48858734_T / C,Chr4B_48858970_A / T,Chr4B_48859081_C / T,Chr4B_48859128_T / G,Chr4B_48859137_T / C,Chr4B_48859175_A / G,Chr4B_48859197_A / G,Chr4B_48859336_G / A,Chr4B_48859361_C / T,Chr4B_48859426_A / T,Chr4B_48859444_G / A,Chr4B_48859552_C / T,Chr4B_48859560_T / C,Chr4B_48859734_A / G,Chr4B_48859762_G / T,Chr4B_48859928_A / T,Chr4B_48860161_G / A,Chr4B_48860181_T / A,Chr4B_48860185_A / G,Chr4B_48860310_C / A,Chr4B_48860345_G / A,Chr4B_48860452_C / T,Chr4B_48860605_G / A,Chr4B_48860765_T / G,Chr4B_48860818_G / A,Chr4B_48860917_T / C,Chr4B_48860969_T / C,Chr4B_48874695_C / T,Chr4B_48874719_G / A,Chr4B_48874824_C / A,Chr4B_48874825_G / A,Chr4B_48875238_G / A,Chr4B_48875245_G / A,Chr4B_48877452_A / G,Chr4B_48878953_T / C,Chr4B_48878962_G / A,Chr4B_48879343_G / T,Chr4B_48879357_C / T,Chr4B_48879516_C / A,Chr4B_48879526_A / G,Chr4B_48879674_G / A,Chr4B_48879748_G / C,Chr4B_48879827_C / T,Chr4B_48880037_A / T,Chr4B_48889152_A / C,Chr4B_48902225_T / C,Chr4B_48902243_G / T,Chr4B_48902261_C / T,Chr4B_48902278_A / G,Chr4B_48902279_T / G,Chr4B_48902288_G / A,Chr4B_48902305_G / A,Chr4B_48902336_A / G,Chr4B_48902356_A / G,Chr4B_48902413_C / T,Chr4B_48904276_C / T,Chr4B_48904411_C / A,Chr4B_48904438_A / T,Chr4B_48904531_C / T,Chr4B_48904817_T / C,Chr4B_48905386_T / A,Chr4B_48905391_T / A,Chr4B_48905573_C / G,Chr4B_48905621_T / C,Chr4B_48905891_G / A,Chr4B_48905936_A / C,Chr4B_48906236_A / G,Chr4B_48906327_T / C,Chr4B_48906367_T / A,Chr4B_48906390_A / C,Chr4B_48906612_T / A,Chr4B_48906962_T / G,Chr4B_48907035_C / T,Chr4B_48907066_T / G,Chr4B_48907100_C / A,Chr4B_48907388_C / T,Chr4B_48907451_G / A,Chr4B_48907603_C / G,Chr4B_48908098_C / A,Chr4B_48908164_T / C,Chr4B_48911152_T / C,Chr4B_48911159_A / C,Chr4B_48911169_A / G,Chr4B_48911195_C / T,Chr4B_48911207_T / C,Chr4B_48911208_G / C,Chr4B_48911214_G / C,Chr4B_48911224_A / G,Chr4B_48911249_T / A,Chr4B_48911299_G / A,Chr4B_48911346_G / C,Chr4B_48911644_G / A,Chr4B_48911645_A / T,Chr4B_48911944_T / C,Chr4B_48911989_T / C,Chr4B_48911991_G / C,Chr4B_48912014_C / G,Chr4B_48912193_G / A,Chr4B_48912194_C / T,Chr4B_48912609_C / T,Chr4B_48912806_G / A,Chr4B_48912935_A / G,Chr4B_48913104_C / T,Chr4B_48913156_G / C,Chr4B_48913169_G / C,Chr4B_48913362_T / C,Chr4B_48913444_T / A,Chr4B_48913482_T / C,Chr4B_48913665_G / T,Chr4B_48913847_C / T,Chr4B_48913916_A / G,Chr4B_48913996_A / G,Chr4B_48914014_C / A,Chr4B_48914057_A / G,Chr4B_48914114_G / A,Chr4B_48914214_A / G,Chr4B_48914397_G / C,Chr4B_48914470_T / A,Chr4B_48914486_T / C,Chr4B_48914667_A / C,Chr4B_48915018_C / T,Chr4B_48915042_C / T,Chr4B_48915126_T / G,Chr4B_48915216_C / G,Chr4B_48915359_G / T,Chr4B_48915440_G / T,Chr4B_48915676_G / A,Chr4B_48915731_T / A,Chr4B_48915736_A / C,Chr4B_48915979_C / T,Chr4B_48915996_A / C,Chr4B_48916009_C / T,Chr4B_48916034_A / G,Chr4B_48916059_G / C,Chr4B_48916075_A / G,Chr4B_48916419_C / A,Chr4B_48916495_C / A,Chr4B_48916774_A / G,Chr4B_48916779_A / C,Chr4B_48916799_C / A,Chr4B_48916821_G / T,Chr4B_48916843_G / T,Chr4B_48916853_T / A,Chr4B_48918411_G / A,Chr4B_48918417_A / G,Chr4B_48918444_G / A,Chr4B_48918447_G / A,Chr4B_48918461_C / T,Chr4B_48918467_C / T,Chr4B_48918471_C / T,Chr4B_48918476_T / C,Chr4B_48918478_G / T,Chr4B_48918482_C / T,Chr4B_48918503_C / T,Chr4B_48918766_T / C,Chr4B_48918891_T / G,Chr4B_48918894_G / A,Chr4B_48918904_T / C,Chr4B_48918938_A / T,Chr4B_48918954_C / T,Chr4B_48918973_T / G,Chr4B_48918979_C / A,Chr4B_48919111_G / C,Chr4B_48919141_A / G,Chr4B_48919199_C / T,Chr4B_49029223_A / G,Chr4B_49029234_A / C,Chr4B_49056742_A / C,Chr4B_49064091_G / T,Chr4B_49142071_T / C,Chr4B_49142097_C / T,Chr4B_49142103_G / A,Chr4B_49220198_T / C,Chr4B_49220253_C / A,Chr4B_49239015_G / A,Chr4B_49448259_C / T,Chr4B_49485831_G / C,Chr4B_49485891_C / A,Chr4B_49506017_C / G,Chr4B_49571712_C / T,Chr4B_49571723_A / G,Chr4B_49571736_T / C,Chr4B_49571741_G / A,Chr4B_49581425_T / G,Chr4B_49598426_C / T,Chr4B_49604899_A / G,Chr4B_49604969_C / G,Chr4B_49604991_T / C,Chr4B_49605023_C / T,Chr4B_49605067_A / G,Chr4B_49605131_G / A,Chr4B_49605164_G / C,Chr4B_49609847_G / C,Chr4B_49609860_G / A,Chr4B_49623193_G / A,Chr4B_49628519_T / A,Chr4B_49635893_A / T,Chr4B_49635898_A / T,Chr4B_49635920_T / C,Chr4B_49762209_T / A,Chr4B_49762218_G / A,Chr4B_49813631_A / G,Chr4B_49846917_T / C,Chr4B_49846918_G / A,Chr4B_49846949_A / G,Chr4B_49846955_A / G,Chr4B_49853939_A / G,Chr4B_49854065_A / G,Chr4B_49858998_T / C,Chr4B_49912881_A / G,Chr4B_49913416_A / C,Chr4B_49914335_A / G,Chr4B_49914345_C / T,Chr4B_49918324_C / T,Chr4B_50017662_G / C,Chr4B_50060236_C / T,Chr4B_50125898_C / T,Chr4B_50125925_T / C,Chr4B_50125932_A / C,Chr4B_50131783_G / T,Chr4B_50131786_T / G,Chr4B_50138056_C / G,Chr4B_50150032_C / T,Chr4B_50165545_A / G,Chr4B_50165572_C / G,Chr4B_50166544_C / G,Chr4B_50529950_T / G,Chr4B_50530187_A / G,Chr4B_50530357_C / A,Chr4B_50531295_C / A,Chr4B_50531989_A / T,Chr4B_50539013_C / T,Chr4B_50579119_C / A,Chr4B_50582818_C / T,Chr4B_50582858_G / A,Chr4B_50599968_T / C,Chr4B_50635885_G / C,Chr4B_50635888_T / C,Chr4B_50636587_A / G,Chr4B_50652258_G / A,Chr4B_50652260_A / G,Chr4B_50700047_A / G,Chr4B_50700048_C / A,Chr4B_50701157_G / T,Chr4B_50701382_T / C,Chr4B_50701428_C / T,Chr4B_50704890_C / T,Chr4B_50704906_G / C,Chr4B_50704983_A / G,Chr4B_50704993_C / T,Chr4B_50711174_T / C,Chr4B_50711181_T / G,Chr4B_50711204_G / T,Chr4B_50723642_T / A,Chr4B_50748427_T / C,Chr4B_50756724_C / T,Chr4B_50756729_A / T,Chr4B_50766521_C / T,Chr4B_50766528_G / A,Chr4B_50766560_T / A,Chr4B_50766605_G / T,Chr4B_50781299_C / T,Chr4B_50783723_A / C,Chr4B_50783909_C / T,Chr4B_50783919_C / T,Chr4B_50797924_A / G,Chr4B_50798600_A / G,Chr4B_50798610_G / A,Chr4B_50798632_T / A,Chr4B_50798641_T / C,Chr4B_50800309_A / G,Chr4B_50800310_T / G,Chr4B_50814627_C / A,Chr4B_50843090_C / T,Chr4B_50864972_C / T,Chr4B_50864973_A / G,Chr4B_50864976_A / G,Chr4B_50870961_A / T,Chr4B_50870964_T / A,Chr4B_50870965_A / G,Chr4B_50870967_T / C,Chr4B_50913634_A / G,Chr4B_50913635_T / A,Chr4B_50942906_G / T,Chr4B_50942968_C / T,Chr4B_50967890_C / T,Chr4B_50967919_T / G,Chr4B_50967942_A / T,Chr4B_50975632_T / C,Chr4B_50975649_A / G,Chr4B_50975703_G / C,Chr4B_50992971_T / C,Chr4B_50993029_T / C,Chr4B_50993062_G / A,Chr4B_50993064_C / A,Chr4B_51083867_G / A,Chr4B_51083885_C / T,Chr4B_51083887_T / A,Chr4B_51083915_A / G,Chr4B_51083924_G / A,Chr4B_51083993_A / G,Chr4B_51083999_T / C,Chr4B_51084005_A / T,Chr4B_51084091_C / T,Chr4B_51084099_A / G,Chr4B_51084177_A / T,Chr4B_51084193_T / C,Chr4B_51084197_C / T,Chr4B_51084227_T / A,Chr4B_51084333_C / T,Chr4B_51084349_A / G,Chr4B_51084511_A / G,Chr4B_51084555_C / A,Chr4B_51084564_G / A,Chr4B_51084578_G / A,Chr4B_51084748_C / T,Chr4B_51099526_C / T,Chr4B_51111126_C / T,Chr4B_51111130_T / C,Chr4B_51159532_G / A,Chr4B_51171790_T / A,Chr4B_51178420_G / A,Chr4B_51187855_T / C,Chr4B_51187858_T / G,Chr4B_51222800_G / T,Chr4B_51223633_T / A,Chr4B_51231633_G / A,Chr4B_51232176_A / G,Chr4B_52034943_C / T,Chr4B_52168797_A / C,Chr4B_52216624_T / C,Chr4B_52216628_T / C,Chr4B_52318358_C / A,Chr4B_52318359_C / G,Chr4B_52318362_G / A,Chr5A_2145606_C / T,Chr5A_2145619_G / A,Chr5A_3765737_C / T,Chr5A_7477573_G / C,Chr5A_7477575_T / A,Chr5A_7477639_A / G,Chr5A_7477709_A / G,Chr5A_7477734_A / G,Chr5A_7873191_T / C,Chr5A_7984083_G / C,Chr5A_8014766_T / A,Chr5A_8015339_C / A,Chr5A_8084692_C / T,Chr5A_8085752_T / C,Chr5A_8085807_T / C,Chr5A_8085809_C / T,Chr5A_8086199_A / G,Chr5A_8086232_A / T,Chr5A_8087852_T / C,Chr5A_8183110_G / A,Chr5A_8196659_C / T,Chr5A_8196686_T / C,Chr5A_8203283_C / T,Chr5A_8267791_G / A,Chr5A_8267823_A / G,Chr5A_8268246_A / G,Chr5A_8268263_T / C,Chr5A_8268277_G / C,Chr5A_8283350_C / T,Chr5A_8347365_T / A,Chr5A_8371676_T / C,Chr5A_8371744_T / C,Chr5A_8671551_T / C,Chr5A_8678823_A / T,Chr5A_8683265_G / C,Chr5A_8707856_C / T,Chr5A_8721775_A / T,Chr5A_8721923_C / T,Chr5A_8731417_A / G,Chr5A_8752278_C / T,Chr5A_8867538_G / A,Chr5A_8867579_C / T,Chr5A_8868200_A / T,Chr5A_8868481_C / A,Chr5A_8868500_G / A,Chr5A_8868516_G / A,Chr5A_8872042_C / T,Chr5A_8899101_A / G,Chr5A_8951655_A / G,Chr5A_8951681_C / T,Chr5A_8951715_A / C,Chr5A_9033294_G / A,Chr5A_9033329_T / A,Chr5A_9033336_G / T,Chr5A_9057487_C / G,Chr5A_9059012_G / A,Chr5A_9059086_G / T,Chr5A_9059444_G / T,Chr5A_9060240_G / A,Chr5A_9062007_C / T,Chr5A_9063142_T / A,Chr5A_9063802_G / A,Chr5A_9075345_A / T,Chr5A_9123272_T / G,Chr5A_9158772_G / A,Chr5A_9331626_A / T,Chr5A_9351415_C / T,Chr5A_9442095_T / C,Chr5A_9442099_A / G,Chr5A_9451206_C / A,Chr5A_9457262_A / C,Chr5A_9687699_T / A,Chr5A_9784919_G / C,Chr5A_9785095_C / A,Chr5A_10225374_T / G,Chr5A_10381394_C / T,Chr5A_10572054_T / A,Chr5A_10572170_G / A,Chr5A_10572324_A / G,Chr5A_10572376_T / C,Chr5A_10572908_G / C,Chr5A_11551922_T / A,Chr5A_11555222_C / G,Chr5A_13742394_A / G,Chr5A_13781034_A / G,Chr5A_20877294_G / A,Chr5A_21130380_C / T,Chr5A_21130867_A / T,Chr5A_21152195_T / A,Chr5A_21153236_A / C,Chr5A_25479553_G / A,Chr5A_46981857_C / T,Chr5A_49607034_A / G,Chr5A_54165103_C / T,Chr5A_54165126_C / T,Chr5A_54165129_A / G,Chr5A_54165132_A / G,Chr5A_54165133_C / T,Chr5A_54165134_G / A,Chr5A_54165158_C / G,Chr5A_54165165_G / T,Chr5A_54165175_C / T,Chr5A_54165218_A / G,Chr5A_54165222_G / A,Chr5A_54165229_A / G,Chr5A_54165231_A / G,Chr5A_54165240_G / A,Chr5A_54165264_C / A,Chr5A_54165270_T / C,Chr5A_54165308_C / T,Chr5A_54165365_T / C,Chr5A_54165374_T / G,Chr5A_54165396_A / C,Chr5A_54165428_C / T,Chr5A_54165435_G / T,Chr5A_54165482_C / T,Chr5A_54165491_C / A,Chr5A_54165493_G / A,Chr5A_54165494_C / T,Chr5A_54165538_A / T,Chr5A_54165552_T / G,Chr5A_54165553_G / A,Chr5A_54165591_A / G,Chr5A_54165717_T / A,Chr5A_54165726_C / G,Chr5A_54165727_T / G,Chr5A_54165729_G / A,Chr5A_54165731_G / T,Chr5A_54165735_A / G,Chr5A_54165738_T / A,Chr5A_54165740_A / G,Chr5A_54165744_A / G,Chr5A_54165746_C / A,Chr5A_54165760_G / T,Chr5A_54165761_T / G,Chr5A_54165793_G / A,Chr5A_54165855_A / G,Chr5A_54165902_A / C,Chr5A_54165981_C / A,Chr5A_54165987_G / A,Chr5A_54166067_G / A,Chr5A_54166073_A / C,Chr5A_54166133_T / G,Chr5A_54166162_C / T,Chr5A_54166173_T / G,Chr5A_54166195_A / T,Chr5A_54166218_A / T,Chr5A_54166223_A / T,Chr5A_54166240_A / C,Chr5A_59922982_C / T,Chr5A_59922997_C / T,Chr5A_59923003_A / G,Chr5A_72965484_G / T,Chr5A_72965485_C / T,Chr5A_80348825_C / T,Chr5A_80348841_T / C,Chr5A_80348855_C / T,Chr5A_80348861_C / A,Chr5A_83462474_G / A,Chr5A_83466258_G / A,Chr5A_83743395_G / A,Chr5A_84058939_T / C,Chr5A_92826191_C / G,Chr5A_92851050_C / T,Chr5B_7144471_T / C,Chr5B_7144480_G / T,Chr5B_7144500_C / T,Chr5B_7144540_G / C,Chr5B_7158588_T / C,Chr5B_7444168_C / T,Chr5B_7573720_T / C,Chr5B_7639553_T / A,Chr5B_7639587_A / G,Chr5B_7660555_G / A,Chr5B_8271493_C / G,Chr5B_8273404_C / T,Chr5B_8273494_G / C,Chr5B_8484537_A / T,Chr5B_18555174_A / G,Chr5B_18573687_C / T,Chr5B_18573689_G / C,Chr5B_27838451_A / G,Chr5B_31922658_G / T,Chr5B_34406890_T / C,Chr5B_34406899_T / C,Chr5B_34406944_T / C,Chr5B_34406950_G / A,Chr5B_34406963_A / T,Chr5B_34406966_A / G,Chr5B_34406974_G / A,Chr5B_34406977_C / T,Chr5B_34407019_A / G,Chr5B_34407031_C / T,Chr5B_34407043_T / C,Chr5B_58957235_G / A,Chr5B_58957555_G / A,Chr5B_66560371_G / A,Chr5B_66787628_A / G,Chr5B_66787651_C / T,Chr5B_66787654_G / A,Chr5B_69447308_C / A,Chr5B_71708579_C / T,Chr5B_75359043_A / C,Chr5B_86379089_G / A,Chr5B_86379720_A / C,Chr5B_86388809_A / C,Chr6A_2860810_C / T,Chr6A_2871864_T / C,Chr6A_2875451_C / G,Chr6A_3014477_C / A,Chr6A_3014541_C / T,Chr6A_3014574_G / A,Chr6A_3014659_G / A,Chr6A_3014734_C / T,Chr6A_3018929_C / T,Chr6A_3035863_C / T,Chr6A_3035876_A / C,Chr6A_3035889_G / A,Chr6A_3035890_G / T,Chr6A_3035897_C / G,Chr6A_3035900_A / G,Chr6A_3035927_C / G,Chr6A_3035930_C / T,Chr6A_3035990_G / T,Chr6A_3036104_G / C,Chr6A_3036471_T / C,Chr6A_3036473_A / G,Chr6A_3036486_C / A,Chr6A_3036523_A / G,Chr6A_3036547_G / A,Chr6A_3036571_G / A,Chr6A_3036641_G / C,Chr6A_3036649_A / T,Chr6A_3036657_T / A,Chr6A_3036659_T / G,Chr6A_3037075_A / C,Chr6A_3037231_G / T,Chr6A_3037248_C / A,Chr6A_3037274_A / C,Chr6A_3037355_T / G,Chr6A_3037359_T / A,Chr6A_3037360_A / C,Chr6A_3191130_G / C,Chr6A_3191163_A / G,Chr6A_3191171_C / G,Chr6A_3191175_G / A,Chr6A_3191198_A / G,Chr6A_3191217_G / A,Chr6A_3191319_C / T,Chr6A_3191324_C / T,Chr6A_3191375_T / A,Chr6A_3305905_G / A,Chr6A_3408572_T / C,Chr6A_32058417_A / G,Chr6A_32058456_T / G,Chr6A_32058467_T / A,Chr6A_32058503_G / C,Chr6A_32058516_A / T,Chr6A_32058557_C / T,Chr6A_32058613_C / T,Chr6A_32058843_A / G,Chr6A_32058867_G / A,Chr6A_39637916_A / G,Chr6A_39637917_G / C,Chr6A_39638306_A / G,Chr6A_39638422_C / T,Chr6A_47365184_G / A,Chr6A_47819280_C / T,Chr6A_47819292_T / C,Chr6A_47819309_T / C,Chr6A_47819330_T / C,Chr6A_47819341_T / C,Chr6A_47819347_G / A,Chr6A_47819437_A / G,Chr6A_47819443_C / T,Chr6A_47819463_T / C,Chr6A_47819470_A / C,Chr6A_47819505_C / T,Chr6A_47876580_G / A,Chr6A_47876640_A / G,Chr6A_47876653_C / T,Chr6A_47876706_C / A,Chr6A_48210286_G / A,Chr6A_48210292_G / A,Chr6A_48210296_A / G,Chr6A_52061430_T / C,Chr6A_52555678_G / A,Chr6A_57590446_G / A,Chr6A_57590632_A / C,Chr6A_58349935_C / G,Chr6A_60701776_G / A,Chr6A_60728861_A / G,Chr6A_60782652_T / A,Chr6A_60782745_C / T,Chr6A_60782768_G / C,Chr6A_60782809_C / A,Chr6A_60826840_A / G,Chr6A_60882086_T / C,Chr6A_61108025_C / A,Chr6A_61142738_C / T,Chr6A_61142783_T / C,Chr6A_61142805_T / A,Chr6A_61142836_T / G,Chr6A_61143100_G / A,Chr6A_61143102_C / T,Chr6A_61144950_T / C,Chr6A_61145115_T / C,Chr6A_61145135_G / T,Chr6A_61145168_C / T,Chr6A_61154121_G / A,Chr6A_61303749_C / T,Chr6A_61303753_G / C,Chr6A_61303754_A / C,Chr6A_61411840_T / G,Chr6A_61757105_G / A,Chr6A_61757166_C / T,Chr6A_63028725_T / G,Chr6A_63056317_T / C,Chr6A_63081906_T / C,Chr6A_63086382_G / A,Chr6A_65460295_G / A,Chr6B_1831961_C / A,Chr6B_1832286_C / T,Chr6B_1832294_C / T,Chr6B_1832471_A / G,Chr6B_1832756_C / A,Chr6B_1832920_C / T,Chr6B_1944910_C / A,Chr6B_1961942_T / C,Chr6B_2079755_C / T,Chr6B_2079798_G / A,Chr6B_2178447_T / C,Chr6B_3780195_A / G,Chr6B_3780205_C / T,Chr6B_3780211_C / A,Chr6B_3898672_T / G,Chr6B_3898699_T / A,Chr6B_5543477_A / G,Chr6B_16703927_A / C,Chr6B_16703942_G / T,Chr6B_16704002_G / T,Chr6B_16704022_T / G,Chr6B_16704027_T / C,Chr6B_16704028_G / A,Chr6B_16704067_T / A,Chr6B_16704070_G / T,Chr6B_16704074_G / T,Chr6B_16704080_G / A,Chr6B_16704098_G / A,Chr6B_18512669_T / A,Chr6B_20541549_G / A,Chr6B_20541655_C / T,Chr6B_20541667_G / A,Chr6B_20541687_C / T,Chr6B_20541704_C / T,Chr6B_20541718_C / T,Chr6B_20541734_A / G,Chr6B_20541893_G / T,Chr6B_20542000_G / C,Chr6B_20542052_C / T,Chr6B_20542103_C / T,Chr6B_20542269_T / C,Chr6B_20545046_G / A,Chr6B_36482617_T / C,Chr6B_36482648_T / G,Chr6B_36482659_G / A,Chr6B_52684073_G / A,Chr6B_54187703_C / G,Chr6B_57547848_T / C,Chr7A_8511_C / T,Chr7A_28729_G / A,Chr7A_28783_G / A,Chr7A_57630_G / T,Chr7A_57964_C / T,Chr7A_68608_C / T,Chr7A_92076_G / A,Chr7A_102085_G / A,Chr7A_102333_A / G,Chr7A_109736_T / C,Chr7A_163742_G / A,Chr7A_216946_C / A,Chr7A_227595_G / A,Chr7A_240344_A / G,Chr7A_240404_G / A,Chr7A_240961_G / C,Chr7A_245391_C / T,Chr7A_247343_C / T,Chr7A_250969_A / G,Chr7A_278940_G / A,Chr7A_285222_C / A,Chr7A_285323_G / A,Chr7A_295009_T / C,Chr7A_325133_A / C,Chr7A_325278_T / C,Chr7A_334656_C / T,Chr7A_334837_G / A,Chr7A_347208_A / C,Chr7A_362676_A / G,Chr7A_362899_C / A,Chr7A_402642_G / T,Chr7A_402839_G / A,Chr7A_419297_G / C,Chr7A_41 9695_G / A,Chr7A_419747_A / T,Chr7A_419848_T / C,Chr7A_419882_T / G,Chr7A_426973_G / A,Chr7A_428083_G / A,Chr7A_438718_G / A,Chr7A_438736_A / G,Chr7A_438754_A / G,Chr7A_454246_C / A,Chr7A_454251_C / T,Chr7A_454257_A / T,Chr7A_454333_A / T,Chr7A_454564_G / T,Chr7A_454566_T / A, Chr7A_477562_A / C,Chr7A_501187_C / T,Chr7A_506921_C / T,Chr7A_506922_G / A,Chr7A_509324_A / C,Chr7A_509747_A / G,Chr7A_511164_A / G,Chr7A_513470_G / A,Chr7A_513544_A / G,Chr7A_514268_T / A,Chr7A_514270_C / T,Chr7A_519908_G / C,Chr7A_536954_C / T,Chr7A_537147_G / A,Chr7A_53 7183_C / T,Chr7A_539703_G / A,Chr7A_547191_C / A,Chr7A_555746_T / C,Chr7A_555765_A / C,Chr7A_555912_G / C,Chr7A_555923_T / C,Chr7A_555933_G / A,Chr7A_569937_T / C,Chr7A_569957_T / A,Chr7A_571334_T / A,Chr7A_609767_A / T,Chr7A_625963_T / G,Chr7A_626203_T / C,Chr7A_653450_T / A,Chr7A_653581_C / T,Chr7A_656985_A / G,Chr7A_657045_T / C,Chr7A_694284_G / A,Chr7A_696525_C / T,Chr7A_697159_A / T,Chr7A_703866_A / T,Chr7A_734983_T / A,Chr7A_744497_T / A,Chr7A_753343_T / A,Chr7A_755065_C / T,Chr7A_760387_G / A,Chr7A_760433_C / T,Chr7A_760436_C / T,Chr7A_760 492_G / C,Chr7A_763513_C / T,Chr7A_763624_C / T,Chr7A_775235_C / A,Chr7A_811430_G / T,Chr7A_824208_A / T,Chr7A_824212_A / T,Chr7A_824216_A / T,Chr7A_824292_T / C,Chr7A_824341_C / A,Chr7A_828802_G / A,Chr7A_830652_G / C,Chr7A_830685_A / T,Chr7A_831463_C / T,Chr7A_831724_T / C,C hr7A_841582_A / G,Chr7A_889584_G / C,Chr7A_889599_T / C,Chr7A_889763_G / A,Chr7A_927985_C / T,Chr7A_928302_A / G,Chr7A_949930_T / C,Chr7A_961941_G / A,Chr7A_1013938_A / T,Chr7A_1051325_C / T,Chr7A_1052565_C / T,Chr7A_1053525_T / C,Chr7A_1053664_G / T,Chr7A_1086896_C / T,Chr7 A_1087082_C / T,Chr7A_1097141_G / T,Chr7A_1097937_A / G,Chr7A_1099080_G / C,Chr7A_1103488_G / A,Chr7A_1103554_G / A,Chr7A_1114072_C / A,Chr7A_1118679_C / T,Chr7A_1120633_G / T,Chr7A_1133458_C / T,Chr7A_1133488_C / T,Chr7A_1201404_T / C,Chr7A_1252817_G / A,Chr7A_1264511_T / C,Chr7A_1282278_G / C,Chr7A_1507287_C / T,Chr7A_1507817_G / A,Chr7A_1507872_C / T,Chr7A_1508951_A / G,Chr7A_1509026_A / T,Chr7A_1509395_C / T,Chr7A_1514597_C / A,Chr7A_1588372_T / C,Chr7A_1594527_A / T,Chr7A_1597098_G / C,Chr7A_1597117_T / A,Chr7A_1648356_A / G,Chr7A_1680719 _C / T,Chr7A_1681118_C / A,Chr7A_1681287_C / T,Chr7A_1681299_A / G,Chr7A_1681389_A / G,Chr7A_1681404_C / A,Chr7A_1703730_G / C,Chr7A_1704694_T / C,Chr7A_1704891_T / A,Chr7A_1706000_C / T,Chr7A_1713822_T / G,Chr7A_1725858_T / C,Chr7A_1726477_T / C,Chr7A_1726610_C / T,Chr7A_172 8286_C / G,Chr7A_1750537_C / T,Chr7A_1750696_G / A,Chr7A_1759533_G / A,Chr7A_1766199_G / T,Chr7A_1898402_A / G,Chr7A_1901964_A / T,Chr7A_1910528_C / G,Chr7A_1924437_A / G,Chr7A_2299446_G / T,Chr7A_2559788_A / C,Chr7A_2572364_T / A,Chr7A_2572395_T / C,Chr7A_2695860_G / T,Chr7 A_2702287_A / G,Chr7A_2742789_T / C,Chr7A_2751951_G / C,Chr7A_2752189_G / A,Chr7A_2823013_C / T,Chr7A_2823021_C / A,Chr7A_2824233_C / T,Chr7A_2865577_G / T,Chr7A_2900455_C / T,Chr7A_2907039_G / A,Chr7A_2907047_C / A,Chr7A_2945068_A / T,Chr7A_2945132_C / T,Chr7A_2945190_C / A,Chr7A_2946001_C / T,Chr7A_2965928_T / C,Chr7A_3016862_T / A,Chr7A_3016904_A / G,Chr7A_3030271_G / T,Chr7A_3037663_A / C,Chr7A_3037721_T / A,Chr7A_3040598_G / A,Chr7A_3040889_G / A,Chr7A_3089207_T / C,Chr7A_3089299_C / G,Chr7A_3089879_G / T,Chr7A_3095569_A / G,Chr7A_3125343 _T / C,Chr7A_3137028_C / T,Chr7A_3147064_G / A,Chr7A_3153107_T / C,Chr7A_3175023_G / A,Chr7A_3270055_G / A,Chr7A_3270139_C / T,Chr7A_3270201_C / T,Chr7A_3270298_C / T,Chr7A_3277976_C / T,Chr7A_3343578_C / T,Chr7A_3361944_A / G,Chr7A_3370624_C / T,Chr7A_3371119_C / T,Chr7A_348 0687_T / A,Chr7A_3494691_A / C,Chr7A_3494726_T / A,Chr7A_3503515_C / G,Chr7A_3513429_T / A,Chr7A_3517549_A / G,Chr7A_3614393_G / T,Chr7A_3614473_C / T,Chr7A_3642095_G / A,Chr7A_3729475_G / A,Chr7A_3729501_A / T,Chr7A_3812904_A / T,Chr7A_3812906_A / C,Chr7A_3907184_G / T,Chr7 A_3975310_A / G,Chr7A_3991805_G / A,Chr7A_4101239_T / C,Chr7A_4126842_C / G,Chr7A_4261533_C / T,Chr7A_4261550_A / G,Chr7A_4279391_C / T,Chr7A_4279416_G / T,Chr7A_4426815_A / G,Chr7A_4615072_A / C,Chr7A_4827645_G / C,Chr7A_4906710_C / T,Chr7A_5154598_A / C,Chr7A_5311548_C / A,Chr7A_5471613_G / A,Chr7A_5477550_C / T,Chr7A_5633791_G / A,Chr7A_6018819_G / T,Chr7A_6018842_T / A,Chr7A_6018857_C / T,Chr7A_6018864_C / T,Chr7A_6018986_A / T,Chr7A_6018999_C / T,Chr7A_6019284_C / T,Chr7A_6019604_C / T,Chr7A_6019606_C / T,Chr7A_6019837_C / T,Chr7A_6037756 _C / T,Chr7A_6043624_G / A,Chr7A_6064505_G / A,Chr7A_6133542_G / T,Chr7A_6133651_T / A,Chr7A_6133735_A / T,Chr7A_6158798_A / T,Chr7A_6158839_C / T,Chr7A_6159134_T / A,Chr7A_6159136_A / G,Chr7A_6159193_G / C,Chr7A_6161105_C / T,Chr7A_6165055_G / T,Chr7A_6165073_T / A,Chr7A_621 6928_C / T,Chr7A_6216933_G / A,Chr7A_6216948_G / T,Chr7A_6238088_T / C,Chr7A_6241402_C / T,Chr7A_6243035_C / T,Chr7A_6243105_T / C,Chr7A_6262463_T / G,Chr7A_6262866_T / C,Chr7A_6262870_A / G,Chr7A_6316597_C / A,Chr7A_6333995_G / A,Chr7A_6336851_T / C,Chr7A_6339594_G / A,Chr7 A_6342182_T / A,Chr7A_6342192_A / C,Chr7A_6343989_A / C,Chr7A_6345547_T / G,Chr7A_6346960_T / A,Chr7A_6353320_A / G,Chr7A_6359301_G / A,Chr7A_6365229_G / A,Chr7A_6375085_C / T,Chr7A_6376265_G / A,Chr7A_6376326_C / T,Chr7A_6376368_C / T,Chr7A_6376389_C / T,Chr7A_6376544_G / A,Chr7A_6376567_C / T,Chr7A_6381657_G / A,Chr7A_6381991_C / T,Chr7A_6381992_T / A,Chr7A_6381993_C / A,Chr7A_6384448_A / G,Chr7A_6402403_A / G,Chr7A_6413847_C / T,Chr7A_6415332_T / C,Chr7A_6432582_A / T,Chr7A_6432708_A / C,Chr7A_6432730_A / T,Chr7A_6433138_T / G,Chr7A_6435099 _C / T,Chr7A_6435223_C / T,Chr7A_6435243_T / C,Chr7A_6459892_C / T,Chr7A_6460041_C / T,Chr7A_6460093_C / T,Chr7A_6460096_C / T,Chr7A_6460192_C / T,Chr7A_6460199_C / A,Chr7A_6460219_A / C,Chr7A_6460259_G / A,Chr7A_6460382_C / T,Chr7A_6493093_C / T,Chr7A_6507576_C / T,Chr7A_651 3010_G / A,Chr7A_6524764_G / A,Chr7A_6527957_C / T,Chr7A_6529441_A / G,Chr7A_6539934_C / T,Chr7A_6546969_G / A,Chr7A_6581004_A / G,Chr7A_6601228_A / G,Chr7A_6601408_A / G,Chr7A_6601424_G / T,Chr7A_6601505_G / C,Chr7A_6606351_C / T,Chr7A_6606740_G / C,Chr7A_6669512_C / A,Chr7 A_6837292_C / T,Chr7A_6880507_A / G,Chr7A_7984748_C / T,Chr7A_8973474_A / G,Chr7A_8973480_C / A,Chr7A_8973486_G / A,Chr7A_8973487_C / G,Chr7A_8973623_T / C,Chr7A_8973630_A / G,Chr7A_8973634_A / C,Chr7A_9661748_T / G,Chr7A_9662728_C / T,Chr7A_9864618_T / C,Chr7A_9864660_G / A,Chr7A_9865147_T / G,Chr7A_9865148_C / T,Chr7A_9865602_T / C,Chr7A_10449473_G / A,Chr7A_10450990_C / A,Chr7A_10451449_C / A,Chr7A_10452092_G / T,Chr7A_11611097_C / A,Chr7A_11710258_T / C,Chr7A_12246903_C / T,Chr7A_12311679_A / G,Chr7A_12311682_T / C,Chr7A_12556745_G / A,Chr7A_12596677_T / C,Chr7A_13175604_G / A,Chr7A_35357292_C / T,Chr7A_36987381_A / C,Chr7A_38993870_G / A,Chr7A_44988187_C / A,Chr7A_62858138_G / A,Chr7A_62858291_C / T,Chr7A_64878323_G / T,Chr7A_64878380_G / C,Chr7B_60268_T / C,Chr7B_175448_G / A,Chr7B_177330_T / G,Chr7B_245611_G / T,Chr7B_245626_A / T,Chr7B_245666_G / A,Chr7B_246036_C / G,Chr7B_246057_G / A,Chr7B_246750_C / A,Chr7B_246768_C / G,Chr7B_259622_C / T,Chr7B_494525_T / C,Chr7B_607033_A / G,Chr7B_610205_G / A,Chr7B_887563_C / A,Chr7B_887745_G / C,Chr7B_1127274_A / T,Chr7B_1127291_T / C,Chr7B_1763991_T / C,Chr7B_1764747_T / A,Chr7B_2158927_A / T,Chr7B_2298583_C / T,Chr7B_3069861_T / G,Chr7B_3153102_C / T,Chr7B_3153249_T / C,Chr7B_3156918_C / G,Chr7B_3157068_T / A,Chr7B_3157182_A / G,Chr7B_3160785_T / G,Chr7B_3160880_A / T,Chr7B_3161405_C / T,Chr7B_3318089_G / A,Chr7B_3321841_C / T,Chr7B_3341245_T / A,Chr7B_3991475_C / T,Chr7B_3994122_G / T,Chr7B_4612234_G / T,Chr7B_4927904_G / T,Chr7B_5752644_A / G,Chr7B_6001894_T / C,Chr7B_6151557_G / A,Chr7B_6167247_G / A,Chr7B_6167282_C / G,Chr7B_6167448 _G / T,Chr7B_7768554_C / G,Chr7B_8174490_G / A,Chr7B_10949999_G / T,Chr7B_23652963_C / T,Chr7B_28743498_C / T,Chr7B_29 588339_A / G,Chr7B_38716545_T / C,Chr7B_38716586_C / T,Chr7B_40388526_G / A,Chr7B_44121844_G / A,Chr7B_44121845_C / T. ,

[0080] SNP loci were identified through genome-wide association analysis of 358 rose resequencing materials, and were screened using multiple software and models.

[0081] Example 2

[0082] The present invention provides a predictive probe for rose leaf gloss. The probe is designed with a combination of SNP sites and its sequence is optimized to have high specificity and high sensitivity, enabling it to accurately capture target SNP sites.

[0083] Example 3

[0084] This invention provides a prediction chip for rose leaf gloss. The prediction chip includes probes for detecting 4746 SNP sites. By detecting the genotype of SNP sites in the genomic DNA of the rose sample to be tested, and using a pre-constructed whole-genome selection model, the gloss trait of rose leaves can be accurately predicted.

[0085] Example 4

[0086] The present invention relates to the application of a combination of SNP molecular markers, probes, or chips in the prediction of rose leaf gloss by extracting genomic DNA from rose plants and using SNP site combinations, probes, or chips for detection.

[0087] Example 5

[0088] The present invention provides a method for predicting the gloss of rose leaves based on SNP molecular marker combinations, comprising the following steps:

[0089] (1) Extract genomic DNA from the rose plants to be tested;

[0090] (2) Constructing a library of genomic DNA;

[0091] (3) Use probes to hybridize and capture DNA fragments in the library to enrich DNA fragments containing target SNP sites;

[0092] (4) Perform high-throughput sequencing on the captured DNA fragments;

[0093] (5) Compare and analyze the sequencing data with the rose reference genome to determine the genotype of the SNP site;

[0094] (6) Input the genotype data of the SNP loci into the whole genome selection model described in claim 4 to obtain the prediction results of the gloss trait of the rose leaves to be tested.

[0095] Lasso had the highest prediction accuracy among the models, with an overall prediction accuracy greater than 0.676.

[0096] Example 6

[0097] The present invention relates to the application of an SNP site combination, probe, chip, or prediction method in rose molecular breeding, which is used to predict and screen the leaf gloss traits of breeding materials in an early, accurate, and efficient manner during the rose breeding process, thereby shortening the breeding cycle, improving selection efficiency, and cultivating new rose varieties with excellent leaf gloss traits.

[0098] A genome-wide selection model based on SNP locus combinations can predict the leaf gloss of roses with an accuracy greater than 0.676.

[0099] Example 7

[0100] The present invention provides a molecular breeding method for roses based on SNP markers, comprising the following steps:

[0101] (1) Extracting genomic DNA from roses;

[0102] (2) Using microarrays to capture and enrich genomic DNA;

[0103] (3) Perform high-throughput sequencing on the captured and enriched DNA;

[0104] (4) Analyze the sequencing data and detect the genotypes of the 4746 SNP sites.

[0105] Example 8

[0106] Genome-wide association analysis of leaf gloss was performed on 358 rose whole-genome resequencing data, including the following workflow:

[0107] (1) Genomic DNA was extracted from 358 rose leaf tissues using the magnetic bead method to construct a whole-genome resequencing library. DNA fragments meeting sequencing requirements were screened using magnetic beads, quantified by qbit, and then sequenced using the BGI DNBSEQ-T7. Figure 2 As shown, Figure 2 The allele frequency map of rose leaf gloss provided by this invention reflects the enrichment degree of target alleles during the breeding process. For example... Figure 3 As shown, Figure 3 The diagram shows the loss rate of luster in rose leaves provided by this invention.

[0108] (2) The fq.gz format second-generation sequencing data obtained in step (1) was compared with the modern rose 'Samantha' genome v2 version (https: / / figshare.com / articles / dataset / i_R_hybrida_i_Samantha_genome_v2 / 28738781?file=53454104) using bwa software. SNP variation data were analyzed using GATK software, ultimately identifying 115,219,112 high-quality SNP loci.

[0109] (3) For the SNP sites screened in step 2, retain those with an allele frequency greater than 0.01. Figure 2 And the missing rate is less than 0.2% for sites ( Figure 3 This yielded 35,335,433 high-quality SNP loci.

[0110] (4) Collection of agronomic traits of leaf gloss. Based on the texture of the upper surface of mature leaves, they were divided into three categories: dull (Category 1); smooth to the touch (Category 2); and leaves with obvious reflectivity (Category 3). Data from three replicate flower types were collected, and the mean and BLUP values ​​were calculated. A total of five data points were obtained for GWAS association analysis.

[0111] (5) Using six models across four software programs—emmax, gemma, rmvp (FARMCPU model, GLM model, MLM model), and tassel (GLM model)—association analysis was performed on leaf gloss agronomic traits. The p-value threshold was set to 1E-4, and a total of 268,779 SNP markers were associated. After deduplication of the association results from different software models, 134,868 SNP loci were obtained. Figure 4 This is a heterogeneity diagram of rose leaf luster provided by the present invention.

[0112] (6) Probe evaluation was performed on the SNPs screened in step (5). The screening criteria were: no InDel markers within 50 bp upstream and downstream of the SNP site; only one copy number of each 100 bp sequence upstream and downstream in the whole genome; GC content between 40-60%; no short repetitive sequences in the sequence; and no N bases in the sequence. After screening, 5100 SNP sites remained.

[0113] (7) The SNP sites selected in step (6) are sorted according to the number of software and models associated with them and the association results. Sites with a large number of software associations and significant association values ​​are selected, and finally, the 4746 SNP markers with the largest number of software associations are determined. For example Figure 1 As shown, Figure 1 The whole chromosome marker distribution map of rose leaf gloss provided by the present invention.

[0114] (8) For the SNP loci selected in step (7), 13 genome-wide selection models were used, including LightGBM (lgb), Random Forest (RF), SVR (svr), Lasso Regression (Lasso), Ridge Regression (Ridge), rrBLUP (rrblup), Reproducing Kernel Hilbert Space (RKHS), Bayes Ridge Regression (BRR), BayesianLasso (BL), BayesC, BayesB, BayesA, and GBLUP, combined with the genotype and floral agronomical traits of 358 accessions, to evaluate the predictive accuracy of leaf gloss. The results showed that Ridge had the lowest predictive accuracy, while Lasso Regression (Lasso) had the highest. The overall predictive accuracy was greater than 0.676, indicating good predictive accuracy. Figure 5 ).

[0115] (9) The SNP sites selected in step (7) are used to synthesize probe sequences for capture sequencing.

[0116] Example 9

[0117] The method for detecting roses using a liquid phase probe corresponding to 4746 SNPs as described in Example 8

[0118] (1) Genomic DNA extraction

[0119] Rose leaves were collected, properly preserved in an ice pack environment, and quickly transported to the laboratory. Total DNA was extracted from the roses using the magnetic bead method.

[0120] (2) Genomic DNA library construction: Genomic DNA is fragmented to a length of 200-300 bp. Then, the ends of the DNA fragments are repaired and adapters are ligated, followed by Pre-PCR amplification to construct the library.

[0121] (3) Hybridization of probes with target regions: The prepared SNP probes are hybridized with the Pre-PCR library. Using streptomycin-modified probes, complementary DNA libraries are captured, thereby enriching the target DNA library. Then, other library DNAs are eluted to obtain the captured Pre-PCR library.

[0122] Hybridization conditions: streptomycin-labeled probes hybridized with the target library at 50°C for 16 h, biotin-labeled magnetic beads bound to streptomycin-labeled probes at room temperature for 30 min to enrich the target library, non-target areas of the library were rinsed with wash buffer, and then eluted with nuclease-free water.

[0123] (4) Magnetic bead purification and amplification: After completing the magnetic bead purification operation, the captured library is amplified so that its DNA concentration reaches the standard required for high-throughput sequencing.

[0124] (5) High-throughput sequencing: The library obtained by capture and amplification in step 4 is subjected to high-throughput sequencing using the BGI Genomics DNBSEQ-T7 sequencing platform to obtain the sequencing results of genomic DNA, and basic cleaning is performed on the obtained data.

[0125] (6) Liquid probe capture rate evaluation: The cleaned sequencing data were compared with the reference sequence of the rose (modern rose 'Samantha' genome v2 version) using bwa software to evaluate the capture efficiency of the liquid probe.

[0126] Experimental Example 1

[0127] Evaluation of liquid phase probe capture efficiency for 12 seasonal varieties

[0128] (1) Experimental materials

[0129] Twelve rose leaf samples were selected, refrigerated, and promptly transported to the laboratory. Total DNA was extracted from each individual plant using the CTAB method. The twelve rose varieties and their numbers are shown in Table 2 below.

[0130] Table 2

[0131]

[0132]

[0133] (2) Capture efficiency evaluation

[0134] Based on the evaluation results of the 12-month-old rose materials, the proportion of detectable SNPs ranged from 97.11% to 98.75%, with a coverage depth of 381.1 to 529.96X. The overall capture efficiency was good, and these samples can be used for subsequent SNP detection and genome-wide selection evaluation. Table 3 shows the statistics of coverage depth and detection rate of leaf sequencing for the 12-month-old rose varieties.

[0135] Table 3

[0136] Sample_ID Coverage depth Detection rate (%) Golden Sun 512.45 97.92 Ferrora Romantic 476.64 98.63 Iver's Rose 497.8 97.11 Butterflies dancing in the sunset 438.58 98.75 A graceful lady 529.96 98.31 Hong Ruisheng 501.86 97.34 Diana 454.06 98.66 Xiang Huanxi 381.1 98.04 lipstick 481.04 98.87 beautiful tits 421.98 98.32 Reading Platform 456.09 98.63 saffron 499.02 97.17

[0137] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the described embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope. The scope of protection of the present invention is defined by the appended claims, the specification, and their equivalents.

Claims

1. A genome-wide SNP molecular marker combinatorial group for rose leaf gloss, characterized in that: The SNP molecular marker combination includes 4746 SNP loci distributed on the 14 chromosomes of rose; the specific information of the SNP loci is represented in the structure of chromosome number_physical location_allele type, and the SNP loci contain dominant alleles that are positively and significantly associated with the gloss of rose leaves. The specific locus information is shown in Table 1 of the specification.

2. The whole-genome SNP molecular marker combination for rose leaf gloss according to claim 1, characterized in that: The SNP sites were determined through genome-wide association analysis of 358 rose resequencing materials, and were screened using multiple software and models.

3. A predictive probe for rose leaf gloss, characterized in that: The probe is designed based on the characteristics of the SNP site combination. Its sequence has been optimized, and it has high specificity and high sensitivity, enabling it to accurately capture the target SNP site.

4. A predictive chip for rose leaf gloss, characterized in that: The prediction chip contains probes for detecting the 4746 SNP sites. By detecting the genotype of the SNP sites in the genomic DNA of the rose sample to be tested, and using a pre-constructed whole-genome selection model, it can accurately predict the gloss trait of rose leaves.

5. The application of the SNP molecular marker combination of claim 1, the probe of claim 3, or the chip of claim 4 in the prediction of rose leaf gloss, characterized in that: The genomic DNA of rose plants is extracted and detected using the SNP site combination, probe, or chip.

6. A method for predicting rose leaf gloss based on the SNP molecular marker combination described in claim 1, characterized in that... Includes the following steps: (1) Extract genomic DNA from the rose plants to be tested; (2) Construct a library from the genomic DNA; (3) Use the probe of claim 3 to hybridize and capture DNA fragments in the library to enrich DNA fragments containing the target SNP site; (4) Perform high-throughput sequencing on the captured DNA fragments; (5) Compare and analyze the sequencing data with the rose reference genome to determine the genotype of the SNP site; (6) Input the genotype data of the SNP loci into the whole genome selection model of claim 4 to obtain the prediction results of the gloss trait of the rose leaves to be tested.

7. The method for predicting rose leaf gloss using SNP molecular marker combinations according to claim 6, characterized in that: Among the models, Bayes Ridge Regression (BRR) has the highest prediction accuracy, with an overall prediction accuracy greater than 0.

738.

8. The application of the SNP site combination, probe, chip, or prediction method according to claim 1 in the molecular breeding of roses, characterized in that: It is used in the rose breeding process to predict and screen the leaf gloss traits of breeding materials in an early, accurate and efficient manner, thereby shortening the breeding cycle, improving selection efficiency, and cultivating new rose varieties with excellent leaf gloss traits.

9. The application of the SNP site combination, probe, chip, or prediction method according to claim 8 in the molecular breeding of roses, characterized in that: The genome-wide selection model constructed based on the SNP site combination can predict the leaf gloss of roses with a prediction accuracy greater than 0.

738.

10. A molecular breeding method for roses based on SNP markers, characterized in that... Includes the following steps: (1) Extracting genomic DNA from roses; (2) Using the chip described in claim 4 to capture and enrich genomic DNA; (3) Perform high-throughput sequencing on the captured and enriched DNA; (4) Analyze the sequencing data to detect the genotypes of the 4746 SNP sites described in claim 1.

Images