Traditional Chinese medicine moisturizing hand cream and preparation method thereof

Abstract

The invention discloses a traditional Chinese medicine moisturizing hand cream and a preparation method thereof. The invention belongs to the technical field of biology, and particularly relates to traditional Chinese medicine moisturizing and nourishing hand cream and a preparation method thereof. The invention provides a composition containing traditional Chinese medicine components. The composition comprises a traditional Chinese medicine extract, a lubricant, an emulsifier and a preservative, the traditional Chinese medicine extract comprises a radix arnebiae seu lithospermi extract or a combination of the radix arnebiae seu lithospermi extract and other component extracts; the lithospermum extract comprises lithospermum oil and a lithospermum aqueous extract; the other component extracts comprise one or a combination of two or three of a rhodiola rosea water extract, an astragalus membranaceus water extract and a liquorice water extract; the traditional Chinese medicine extracts are respectively prepared and then mixed. Through self-compatibility and synergistic effects of pure natural plant components (such as radix arnebiae seu lithospermi anti-inflammation, rhodiola rosea anti-oxidation and radix astragali and radix glycyrrhizae moisturizing and repairing), the comprehensive effects of moisturizing, moistening and repairing are achieved, it is ensured that the product is safe, mild and non-irritant, and meanwhile high-value development and utilization of traditional Chinese medicine resources in the field of modern daily chemicals are promoted.

Description

Technical Field

[0001] This invention belongs to the field of biotechnology, specifically relating to a traditional Chinese medicine moisturizing hand cream and its preparation method. Background Technology

[0002] In recent years, plant extracts have garnered significant attention in the skincare field due to their remarkable moisturizing and other natural active effects. Comfrey extract, with its moisturizing and anti-inflammatory properties, is traditionally used in skin repair preparations such as comfrey ointment. Rhodiola rosea extract's characteristic component, rhodioloside, has been shown to possess antioxidant, whitening, and anti-radiation effects, and can promote collagen production to improve wrinkles. Astragalus extract contains baicalin and baicalein, which have been proven to have antioxidant, anti-inflammatory, antibacterial, and anti-UV properties, and are widely used in skin whitening and sun protection products. Glycyrrhizic acid and glycyrrhizin in licorice extract can synergistically achieve moisturizing, anti-inflammatory, and whitening effects. All four of these extracts are included in the "Cosmetic Ingredients Catalogue (2021 Edition)".

[0003] Hands, as a key part of the body constantly exposed to the external environment, are continuously subjected to ultraviolet radiation, environmental pollution, and chemical erosion, easily leading to dryness, roughness, and even accelerated aging. Hand cream is therefore an essential part of daily skincare. Currently, commercially available hand creams can be categorized by function into protective (relying on physical or chemical sunscreens), moisturizing (containing humectants and water-retaining agents), repairing (containing anti-aging ingredients such as niacinamide), and exfoliating (containing exfoliating particles such as salicylic acid). However, the use of chemically synthesized substances is quite common in current commercially available hand creams. For example, artificial fragrances may irritate delicate skin and cause discomfort. Commonly used moisturizing ingredients such as mineral oil, paraffin, silicone oil, and other petroleum derivatives and synthetic oils have a thick texture that may affect skin breathability and hinder skin respiration. Similarly, synthetic substances used for moisturizing and thickening, such as white petrolatum and stearic acid, can also easily lead to similar breathability problems with long-term use. Furthermore, some additives, such as pigments, ethanol, and strong surfactants, can exacerbate damage to dry and delicate skin with long-term use, causing skin problems. In general, while relying on chemical raw material systems to achieve moisturizing and thickening effects, it is often difficult to meet consumers' urgent need for truly gentle, non-irritating hand creams rich in natural active ingredients.

[0004] While "natural moisturizing" hand creams are available on the market, their moisturizing and hydrating functions primarily rely on petroleum-based chemical synthetic raw materials such as white petrolatum and stearic acid. Some products add small amounts of traditional Chinese medicine extracts as active ingredients. However, there are currently no research reports on hand cream formulas that use comfrey extract as the core active ingredient, in combination with extracts of various traditional Chinese medicines such as rhodiola rosea, astragalus, and licorice, and rely entirely on natural plant components to achieve comprehensive efficacy. This technological gap urgently needs to be filled. Developing a hand cream based on all-natural ingredients that combines moisturizing and repairing functions while avoiding allergens has significant market value and application prospects. Summary of the Invention

[0005] The main problem this invention aims to solve is how to prepare a hand cream with natural ingredients that combines moisturizing and repairing functions.

[0006] To address the above problems, the present invention provides a composition containing traditional Chinese medicine components.

[0007] This invention provides a composition containing traditional Chinese medicine components, characterized in that the composition includes traditional Chinese medicine extracts, lubricants, emulsifiers, and preservatives; the traditional Chinese medicine extracts include Lithospermum erythrorhizon extract, or a combination of Lithospermum erythrorhizon extract and other component extracts;

[0008] The comfrey extract comprises comfrey oil and comfrey aqueous extract;

[0009] The other component extracts include one, two, or three combinations of Rhodiola rosea water extract, Astragalus membranaceus water extract, and Glycyrrhiza uralensis water extract;

[0010] The herbal extracts were prepared separately and then mixed together.

[0011] The method for preparing the comfrey oil in the above composition is as follows:

[0012] By weight, first grind the root of Lithospermum erythrorhizon into powder and pass it through a 40-mesh sieve. Weigh 50g of Lithospermum erythrorhizon powder and place it in an Erlenmeyer flask. Add 200mL of tea tree seed oil. Heat the mixture in a 90℃ constant temperature water bath for 1 hour. After cooling to room temperature, extract it at 4℃ for 2 weeks. After filtration, obtain the Lithospermum erythrorhizon oil.

[0013] The preparation method of the water extract of Lithospermum erythrorhizon is as follows:

[0014] Weigh 50g of the filtered Lithospermum erythrorhizon powder after extracting the oily components, add 10 times the amount of distilled water, extract 3 times, 1 hour each time, combine the filtrates and filter to obtain 500mL of Lithospermum erythrorhizon water extract.

[0015] The preparation method of the Rhodiola rosea water extract is as follows:

[0016] By weight, the Rhodiola rosea root was ground into powder and passed through a 40-mesh sieve. 50g of Rhodiola rosea powder was weighed and 8 times the amount of distilled water was added. Each extraction was performed for 30 minutes. After 3 extractions, the filtrates were combined and filtered to obtain 500mL of Rhodiola rosea water extract.

[0017] The preparation method of the Astragalus membranaceus aqueous extract is as follows:

[0018] By weight, grind the Astragalus root into powder and pass it through a 40-mesh sieve. Weigh 50g of Astragalus powder, add 10 times the amount of distilled water, and extract for 1 hour each time. After 3 extractions, combine the filtrates and filter to obtain 500mL of Astragalus water extract.

[0019] The method for preparing the licorice water extract is as follows:

[0020] Grind the licorice root into powder and pass it through a 40-mesh sieve by weight. Weigh 50g of astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After two extractions, combine the filtrates and filter to obtain 500mL of licorice water extract.

[0021] The combination of the Lithospermum erythrorhizon aqueous extract with other component extracts is as follows:

[0022] 1) The water extract of Lithospermum erythrorhizon and the water extract of Rhodiola rosea are combined in a weight ratio of 0.5 to 2:1;

[0023] 2) The aqueous extract of Lithospermum erythrorhizon and the aqueous extract of Glycyrrhiza uralensis are combined in a weight ratio of 0.5 to 2:1;

[0024] 3) The aqueous extract of Lithospermum erythrorhizon and the aqueous extract of Astragalus membranaceus are combined in a weight ratio of 0.5 to 2:1;

[0025] 4) The water extracts of Lithospermum erythrorhizon, Rhodiola rosea, and Glycyrrhiza uralensis are combined in a weight ratio of 1 to 2:1:1.

[0026] 5) The water extracts of Lithospermum erythrorhizon, Rhodiola rosea, Astragalus membranaceus, and Glycyrrhiza uralensis are combined in a weight ratio of 1:1:1:1.

[0027] In the above composition, the comfrey oil and the lubricant form a mixture, and the ratio of the emulsifier to the mixture is 1:3 to 7 by weight.

[0028] In the above composition, the lubricant is olive oil; the emulsifier is olive oil emulsified wax; the preservative is phenoxyethanol; and the flavoring agent is jasmine essential oil.

[0029] The composition contains, by weight, 12 parts of comfrey oil, 68 parts of olive oil, 20 parts of olive oil emulsifying wax, 74 parts of comfrey water extract, 74 parts of rhodiola rosea water extract, 74 parts of astragalus water extract, 74 parts of licorice water extract, 4 parts of phenoxyethanol, and 1 part of jasmine essential oil.

[0030] The present invention also provides the use of the composition described above in the preparation of hand cream.

[0031] This invention also provides a method for preparing a traditional Chinese medicine moisturizing hand cream, characterized in that the method includes the following steps:

[0032] 1) Preparation of extracts from traditional Chinese medicine:

[0033] The herbal extracts include Lithospermum erythrorhizon extract, or a combination of Lithospermum erythrorhizon extract and other component extracts;

[0034] The comfrey extract comprises comfrey oil and comfrey aqueous extract;

[0035] The other component extracts include one, two, or three combinations of Rhodiola rosea water extract, Astragalus membranaceus water extract, and Glycyrrhiza uralensis water extract;

[0036] The preparation method of the comfrey oil is as follows:

[0037] By weight, first grind the root of Lithospermum erythrorhizon into powder and pass it through a 40-mesh sieve. Weigh 50g of Lithospermum erythrorhizon powder and place it in an Erlenmeyer flask. Add 200mL of tea tree seed oil. Heat the mixture in a 90℃ constant temperature water bath for 1 hour. After cooling to room temperature, extract it at 4℃ for 2 weeks. After filtration, obtain the Lithospermum erythrorhizon extract.

[0038] The preparation method of the water extract of Lithospermum erythrorhizon is as follows:

[0039] Weigh 50g of the filtered Lithospermum erythrorhizon powder after extracting the oily components, add 10 times the amount of distilled water, extract 3 times, 1 hour each time, combine the filtrates and filter to obtain 500mL of Lithospermum erythrorhizon water extract.

[0040] The preparation method of the Rhodiola rosea water extract is as follows:

[0041] By weight, the Rhodiola rosea root was ground into powder and passed through a 40-mesh sieve. 50g of Rhodiola rosea powder was weighed and 8 times the amount of distilled water was added. Each extraction was performed for 30 minutes. After 3 extractions, the filtrates were combined and filtered to obtain 500mL of Rhodiola rosea water extract.

[0042] The preparation method of the Astragalus membranaceus aqueous extract is as follows:

[0043] By weight, grind the Astragalus root into powder and pass it through a 40-mesh sieve. Weigh 50g of Astragalus powder, add 10 times the amount of distilled water, and extract for 1 hour each time. After 3 extractions, combine the filtrates and filter to obtain 500mL of Astragalus water extract.

[0044] The method for preparing the licorice water extract is as follows:

[0045] Grind the licorice root into powder and pass it through a 40-mesh sieve by weight. Weigh 50g of astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After two extractions, combine the filtrates and filter to obtain 500mL of licorice water extract.

[0046] 2) Prepare material A, which is the combination of comfrey oil, olive oil and olive oil emulsified wax mentioned in step 1); prepare material B, which is the combination of comfrey water extract, rhodiola rosea water extract, licorice water extract and astragalus water extract mentioned in step 1).

[0047] 3) Add material B to material A, melt and stir evenly at 80-85℃ to emulsify, and obtain material N;

[0048] 4) Add preservatives and essential oils to material N, stir well, and cool to room temperature to obtain the hand cream.

[0049] In the above method, the combination of traditional Chinese medicine extracts consists of the following parts by weight of traditional Chinese medicine: 12 parts of Lithospermum erythrorhizon oil, 74 parts of Lithospermum erythrorhizon aqueous extract, 74 parts of Rhodiola rosea aqueous extract, 74 parts of Astragalus membranaceus aqueous extract, and 74 parts of Glycyrrhiza uralensis aqueous extract.

[0050] In the above method, the preservative in step 4) is phenoxyethanol.

[0051] In the above method, the essential oil mentioned in step 4) is jasmine essential oil.

[0052] The hand cream product prepared by the method described above also falls within the scope of protection of this invention.

[0053] In one specific embodiment, the hand cream contains 12 parts of comfrey oil, 68 parts of olive oil, 20 parts of olive oil emulsified wax, 74 parts of comfrey water extract, 74 parts of rhodiola rosea water extract, 74 parts of astragalus water extract, 74 parts of licorice water extract, 4 parts of phenoxyethanol, and 1 part of jasmine essential oil.

[0054] This invention provides a hand cream with comfrey extract as the core, combined with extracts of various traditional Chinese medicines such as Rhodiola rosea, Astragalus membranaceus, and Glycyrrhiza uralensis. It completely abandons petroleum-based synthetic raw materials and achieves comprehensive moisturizing, nourishing and repairing effects through the self-compatibility and synergistic effect of pure natural plant components (such as the anti-inflammatory effect of comfrey, the antioxidant effect of Rhodiola rosea, and the moisturizing and repairing effects of Astragalus membranaceus and Glycyrrhiza uralensis). It ensures that the product is safe, gentle and non-irritating, while promoting the high-value development and utilization of traditional Chinese medicine resources in the modern daily chemical industry. Attached Figure Description

[0055] Figure 1 The results of stability tests for hand creams A1-A5 at different temperatures.

[0056] Figure 2 The results show the stability of hand creams A1-A5 at different rotation speeds.

[0057] Figure 3 The results of stability tests for hand creams B1-B12 at different temperatures.

[0058] Figure 4 The results show the stability of hand creams B1-B12 at different rotation speeds. Detailed Implementation

[0059] The present invention will now be described in further detail with reference to specific embodiments. The given embodiments are merely illustrative of the invention and not intended to limit its scope. The embodiments provided below can serve as a guide for further improvements by those skilled in the art and do not constitute a limitation on the invention in any way.

[0060] Unless otherwise specified, the experimental methods used in the following examples are conventional methods, performed according to the techniques or conditions described in the literature in this field or according to the product instructions. Unless otherwise specified, the materials and reagents used in the following examples are commercially available.

[0061] Unless otherwise specified, the quantitative experiments in the following examples are all repeated three times, and the results are averaged.

[0062] The Lithospermum erythrorhizon, Rhodiola rosea, Glycyrrhiza uralensis, and Astragalus membranaceus used in the following examples were purchased from the Bozhou Traditional Chinese Medicine Commodity Trading Center.

[0063] Tea tree seed oil (Guangzhou Youpin Cosmetic Raw Materials Co., Ltd., CAS No.: 22374-13-8), olive oil (Guangzhou Baiyu Biotechnology Co., Ltd., CAS No.: 8001-25-0), olive oil emulsifying wax (Guangzhou Weini Cosmetic Raw Materials Store, CAS No.: 92202-01-2), phenoxyethanol (Guangzhou Baiyu Biotechnology Co., Ltd., CAS No.: 122-99-6).

[0064] Example 1: Preparation method of comfrey extract hand cream

[0065] 1. Extraction method of comfrey oil

[0066] The preparation of comfrey oil was carried out by hot extraction. Comfrey root was ground into powder and passed through a 40-mesh sieve. 50g of comfrey powder was weighed and added to 200ml of tea tree seed oil. The mixture was heated in a 90℃ constant temperature water bath for 1 hour and then cooled to room temperature. After soaking and extraction at 4℃ for 2 weeks, it was filtered to obtain 125mL of comfrey oil extract with a material-to-liquid ratio of 0.25g / mL.

[0067] 2. Extraction method of water extract of Lithospermum erythrorhizon

[0068] Weigh 50g of the extracted oily components and filtered lithospermum powder, add 10 times the amount of distilled water, extract 3 times, 1 hour each time, combine the filtrates and filter to obtain 500mL of lithospermum water extract.

[0069] 3. Preparation of hand cream containing comfrey extract

[0070] Comfrey oil and olive oil were mixed to obtain a mixture. The experiment selected the following ratios of olive oil emulsified wax with the mixture formed by comfrey oil and olive oil: A1 (1:7); A2 (1:6); A3 (1:5); A4 (1:4); A5 (1:3) to screen out the component A basic formula with the best performance.

[0071] Table 1. Selection of component A ratio for hand cream (by parts by weight)

[0072]

[0073] Take a 50ml beaker and add component A in the order of mass. Heat in a water bath to 80-85℃ and stir until homogeneous. In another beaker, add component B and heat in a water bath to 80-85℃, stirring until homogeneous. Slowly add the homogeneously melted component B to component A, stirring constantly to ensure thorough mixing and emulsification for 15 minutes. When the system temperature reaches 40-50℃, add component C and continue stirring for 3-5 minutes. After cooling to room temperature, the comfrey extract hand cream is ready.

[0074] Example 2: Performance Test of Comfrey Extract Hand Cream

[0075] 1. pH detection

[0076] National standards stipulate that the pH value of creams and ointments should be within the range of 4.0 to 8.5. Take 0.5g of the sample obtained in Example 1, dilute it with 10 times the amount of distilled water, heat to dissolve, stir to mix thoroughly, and cool to room temperature. Measure and record the pH value according to the method specified in GB / T13531.1—2008 "General Test Methods for Cosmetics: Determination of pH Value".

[0077] 2. Cold and heat resistance test

[0078] According to the evaluation method of standard QB / T 1857—2013 "Moisturizing Creams", the hand cream was placed in a constant temperature box at (40±1)℃ and a refrigerator at (-20±1)℃ for 24 hours. After being taken out and restored to room temperature, it was observed whether there was any water-oil separation or other changes.

[0079] 3. Stability testing

[0080] According to the evaluation method of standard QB / T1857-2013 "Moisturizing Creams", take an appropriate amount of hand cream samples with different formulas and put them into EP tubes. The rotation speed is set to 2000 r / min and 4000 r / min respectively. After centrifugation for 30 min, take them out and observe whether there is water-oil separation or other changes.

[0081] 4. Evaluation of moisturizing performance

[0082] Based on the method of Sheng Wenbin et al. for measuring the skin care performance of hand cream, the skin moisture content of each sample was tested and recorded before and 30 minutes after use using a smart skin moisture meter, so as to compare the moisturizing effect of hand creams with different formulas.

[0083] The test results are as follows:

[0084] 1) The pH test results are shown in Table 2 below. The pH values ​​of A1-A5 are all within the range of 4.0 to 8.5, which meets the national standard requirements.

[0085] Table 2. pH values ​​of hand creams with different base ratios

[0086] serial number A1 A2 A3 A4 A5 pH 7.57 7.42 7.59 7.43 7.37

[0087] 2) Results of cold and heat resistance tests are as follows Figure 1 As shown: After being kept in a constant temperature chamber at (40±1)℃ for 24 hours, hand creams A1, A2, and A5 all showed varying degrees of oil-water separation, indicating that the base ratios of A1, A2, and A5 had poor heat resistance; after being kept in a refrigerator at (-20±1)℃ for 24 hours, all hand creams A1-A5 were in good condition, indicating that the cold resistance of hand creams A1-A5 was excellent, confirming that the base ratios of A3 and A4 met the requirements.

[0088] 3) Stability test results are as follows Figure 2 As shown: at a speed of 2000 r / min, after centrifugation for 30 min, only A5 showed water-oil separation, indicating that the stability of hand cream A5 was poor at 2000 r / min. At a speed of 4000 r / min, after centrifugation for 30 min, hand creams A1, A2, A3, and A5 all showed varying degrees of water-oil separation, indicating that the stability of hand creams A1, A2, A3, and A5 was poor at 4000 r / min, confirming that the matrix ratio of A4 met the requirements.

[0089] 4) The results of the moisturizing performance evaluation are shown in Table 3. The average skin moisture content before using the hand cream was 22. After use, it was found that A4 had the highest moisture content of 79, followed by A1 and A3, which were 71 and 70 respectively. It was determined that A4 had the best moisturizing effect based on the base ratio.

[0090] Table 3. Results of skin moisture measurement for hand creams with different base ratios

[0091]

[0092]

[0093] Based on the comprehensive performance test results, under laboratory conditions, the pH values ​​of hand creams A1-A5 all met the national standards. The A3 and A4 base ratios were found to perform best in cold and heat resistance tests. The A3 and A4 base ratios also performed well in stability and skincare performance tests, with A4 showing outstanding performance. Therefore, the A3 and A4 formulas can be used as basic hand cream formulas. The A3 formula consists of 3 parts comfrey oil, 22 parts olive oil, 5 parts olive oil emulsifying wax, 69 parts comfrey water extract, and 1 part phenoxyethanol. The A4 formula consists of 3 parts comfrey oil, 17 parts olive oil, 5 parts olive oil emulsifying wax, 74 parts comfrey water extract, and 1 part phenoxyethanol.

[0094] Example 3: Selection and Performance Testing of Compound Extract Hand Cream Formula

[0095] 1. The extraction method of comfrey oil is the same as step 1 in Example 1.

[0096] 2. The preparation and extraction method of the water extract of Lithospermum erythrorhizon is the same as step 2 in Example 1.

[0097] 3. Preparation of Rhodiola rosea water extract

[0098] Rhodiola rosea root was ground into powder and passed through a 40-mesh sieve. 50g of Rhodiola rosea powder was weighed and 8 times the amount of distilled water was added. Each extraction lasted 30 minutes. After extraction, the filtrates were combined and filtered to obtain 500mL of Rhodiola rosea water extract.

[0099] 4. Preparation of Astragalus membranaceus water extract

[0100] Grind the Astragalus root into powder and pass it through a 40-mesh sieve. Weigh 50g of Astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After three extractions, combine the filtrates and filter to obtain 500mL of Astragalus water extract.

[0101] 5. Preparation of licorice water extract

[0102] Grind licorice root into powder and pass it through a 40-mesh sieve. Weigh 50g of astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After two extractions, combine the filtrates and filter to obtain 500mL of licorice water extract.

[0103] 6. Preparation of compound extract hand cream

[0104] Based on the optimal component A ratio formulation selected in Example 1, i.e., formulation A4, the proportions of the compound extracts were compared. Twelve gradients were set, specifically grouped as follows:

[0105] The ratio of Lithospermum erythrorhizon aqueous extract to Rhodiola rosea aqueous extract is B1 (2:1); B2 (1:1); B3 (1:2);

[0106] The ratio of Lithospermum erythrorhizon aqueous extract to Glycyrrhiza uralensis aqueous extract is B4 (2:1); B5 (1:1); B6 (1:2);

[0107] The ratio of Lithospermum erythrorhizon aqueous extract: Rhodiola rosea aqueous extract: Glycyrrhiza uralensis aqueous extract is B7 (1:1:1); B8 (2:1:1);

[0108] The ratio of Lithospermum erythrorhizon aqueous extract to Astragalus membranaceus aqueous extract was B9 (2:1); B10 (1:1); B11 (1:2);

[0109] The ratio of Lithospermum erythrorhizon aqueous extract, Rhodiola rosea aqueous extract, Astragalus membranaceus aqueous extract, and Glycyrrhiza uralensis aqueous extract is B12 (1:1:1:1).

[0110] Table 4. Selection of Extract Ratio for Hand Cream Component B (by Parts by Mass)

[0111]

[0112]

[0113] Take a 50ml beaker and add the optimal ratio component A selected in Example 1 in sequence according to mass. Heat in a water bath to 80-85℃ and stir until homogeneous. Take another beaker and add component B as described in Table 4. Heat in a water bath to 80-85℃ and stir until homogeneous. Slowly add the homogeneously melted component B to component A while stirring to ensure thorough mixing and emulsification for 15 minutes. When the system temperature reaches 40-50℃, add component C as described in Table 1 and continue stirring for 3-5 minutes. After cooling to room temperature, the compound extract hand cream is obtained.

[0114] 7. Performance Test of Compound Extract Hand Cream

[0115] The performance testing method for the compound extract hand cream is the same as in Example 2.

[0116] The test results for the compound extract hand cream are as follows:

[0117] 1) The pH test results are shown in Table 5 below. The pH values ​​of B1-B12 are all within the range of 4.0 to 8.5, which meets the national standard requirements.

[0118] Table 5. pH values ​​of compound extract hand creams, calculated as component B.

[0119] serial number B1 B2 B3 B4 B5 B6 pH 7.67 7.51 7.23 7.39 7.38 7.12 serial number B7 B8 B9 B10 B11 B12 pH 7.32 7.37 7.53 7.51 7.49 7.43

[0120] 2) Results of cold and heat resistance tests are as follows Figure 3 As shown: After being kept in a constant temperature chamber at (40±1)℃ for 24 hours, all hand creams B1-B12 were in good condition, indicating that all hand creams B1-B12 had excellent heat resistance; after being kept in a refrigerator at (-20±1)℃ for 24 hours, all hand creams B1-B12 were in good condition, indicating that all hand creams B1-B12 had excellent cold resistance, and hand creams B1-B12 met the requirements.

[0121] 3) Stability test results are as follows Figure 2 As shown: at a speed of 2000 r / min, after centrifugation for 30 min, B2, B3, and B6 exhibited water-oil stratification, indicating that the stability of hand creams B2, B3, and B6 was poor at 2000 r / min. At a speed of 4000 r / min, after centrifugation for 30 min, except for hand creams B9, B10, B11, and B12, all others showed varying degrees of water-oil stratification, indicating that hand creams B9, B10, B11, and B12 had better stability at 4000 r / min, confirming that the matrix ratios of B9, B10, B11, and B12 met the requirements.

[0122] 4) The results of the moisturizing performance evaluation are shown in Table 6. The average skin moisture content before using the hand cream was 20. After use, it was found that B12 had the highest moisture content of 80, followed by B10 and B11, which were 71 and 73 respectively. It was determined that the compound ratio of B12 extract had the best moisturizing effect.

[0123] Table 6. Skin care performance test results of hand creams B1-B12

[0124]

[0125] Based on the comprehensive performance test results, under laboratory conditions, the pH values ​​of hand creams B1-B12 all met the national standards. The B1-B12 matrix ratios showed the best performance in cold and heat resistance tests; the B9, B10, B11, and B12 matrix ratios showed the best performance in stability tests; and hand cream B12 showed the best performance in skin care performance tests. In conclusion, formulas B10, B11, and B12 can be used as compound extract formulas for hand creams, with formula B12 showing the best performance. Formula B10 consists of: 3 parts comfrey oil, 17 parts olive oil, 5 parts olive oil emulsifying wax, 37 parts comfrey water extract, 37 parts astragalus water extract, and 1 part phenoxyethanol; Formula B11 consists of: 3 parts comfrey oil, 17 parts olive oil, 5 parts olive oil emulsifying wax, 25 parts comfrey water extract, 49 parts astragalus water extract, and 1 part phenoxyethanol; The optimal formula B12 consists of: 6 parts comfrey oil, 34 parts olive oil, 10 parts olive oil emulsifying wax, 37 parts comfrey water extract, 37 parts rhodiola rosea water extract, 37 parts astragalus water extract, 37 parts licorice water extract, and 2 parts phenoxyethanol.

[0126] Example 4: Preparation and sensory evaluation of hand creams with different fragrances

[0127] 1. Preparation of hand creams with different scents

[0128] Based on the optimal formula selected in Examples 1 and 3, namely the B12 formula, different fragrances of the hand cream were compared. Rose essential oil and jasmine essential oil were used as flavor modifiers, with two gradients for each essential oil, for a total of four gradients.

[0129] Table 7. Selection of Essential Oil Ratios for Hand Cream

[0130]

[0131]

[0132] Take a 50ml beaker and add the optimal ratio component A selected in Example 1 in sequence according to mass. Heat in a water bath to 80-85℃ and stir until homogeneous. Take another beaker and add the optimal ratio component B selected in Example 3. Heat in a water bath to 80-85℃ and stir until homogeneous. Slowly add the homogeneously melted component B to component A while stirring to ensure thorough mixing and emulsification for 15 minutes. When the system temperature reaches 40-50℃, add component C and essential oil and continue stirring for 3-5 minutes. After cooling to room temperature, hand creams with different fragrances are obtained.

[0133] 2. Sensory evaluation

[0134] Apply an appropriate amount of hand cream to your hands and smell it close to your nose to identify the product's aroma. The degree of fragrance can be evaluated by no fragrance, light fragrance, and strong fragrance. The results are shown in Table 8: C3 has a better fragrance.

[0135] Table 8. Fragrance Evaluation of C1-C4 Hand Creams

[0136] serial number evaluate C1 Rich aroma C2 Rich aroma C3 Fresh fragrance C4 Rich aroma

[0137] The above experiments show that, under laboratory conditions, C3 hand cream has the best sensory evaluation. Therefore, C3 is determined to be the optimal fragrance choice.

[0138] In summary, the optimal formula for hand cream is: 12 parts comfrey oil, 68 parts olive oil, 20 parts olive oil emulsifying wax, 74 parts comfrey water extract, 74 parts rhodiola rosea water extract, 74 parts astragalus water extract, 74 parts licorice water extract, 4 parts phenoxyethanol, and 1 part jasmine essential oil.

[0139] The present invention has been described in detail above. Those skilled in the art will recognize that the invention can be practiced in a wide range of ways with equivalent parameters, concentrations, and conditions without departing from its spirit and scope, and without requiring unnecessary experiments. While specific embodiments have been provided, it should be understood that further modifications can be made to the invention. In summary, according to the principles of the invention, this application is intended to include any changes, uses, or improvements to the invention, including changes made using conventional techniques known in the art that depart from the scope disclosed herein.

Claims

1. A composition containing traditional Chinese medicine components, characterized in that, The composition includes a traditional Chinese medicine extract, a lubricant, an emulsifier, and a preservative; the traditional Chinese medicine extract includes Lithospermum erythrorhizon extract, or a combination of Lithospermum erythrorhizon extract and other component extracts; The comfrey extract comprises comfrey oil and comfrey aqueous extract; The other component extracts include one, two, or three combinations of Rhodiola rosea water extract, Astragalus membranaceus water extract, and Glycyrrhiza uralensis water extract; The herbal extracts were prepared separately and then mixed together.

2. The composition according to claim 1, characterized in that, The preparation method of the comfrey oil is as follows: By weight, first grind the root of Lithospermum erythrorhizon into powder and pass it through a 40-mesh sieve. Weigh 50g of Lithospermum erythrorhizon powder and place it in an Erlenmeyer flask. Add 200mL of tea tree seed oil. Heat the mixture in a 90℃ constant temperature water bath for 1 hour. After cooling to room temperature, extract it at 4℃ for 2 weeks. After filtration, obtain the Lithospermum erythrorhizon oil. The preparation method of the water extract of Lithospermum erythrorhizon is as follows: Weigh 50g of the filtered Lithospermum erythrorhizon powder after extracting the oily components, add 10 times the amount of distilled water, extract 3 times, 1 hour each time, combine the filtrates and filter to obtain 500mL of Lithospermum erythrorhizon water extract. The preparation method of the Rhodiola rosea water extract is as follows: By weight, the Rhodiola rosea root was ground into powder and passed through a 40-mesh sieve. 50g of Rhodiola rosea powder was weighed and 8 times the amount of distilled water was added. Each extraction was performed for 30 minutes. After 3 extractions, the filtrates were combined and filtered to obtain 500mL of Rhodiola rosea water extract. The preparation method of the Astragalus membranaceus aqueous extract is as follows: By weight, grind the Astragalus root into powder and pass it through a 40-mesh sieve. Weigh 50g of Astragalus powder, add 10 times the amount of distilled water, and extract for 1 hour each time. After 3 extractions, combine the filtrates and filter to obtain 500mL of Astragalus water extract. The method for preparing the licorice water extract is as follows: Grind the licorice root into powder and pass it through a 40-mesh sieve by weight. Weigh 50g of astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After two extractions, combine the filtrates and filter to obtain 500mL of licorice water extract. The combination of the Lithospermum erythrorhizon aqueous extract with other component extracts is as follows: 1) The water extract of Lithospermum erythrorhizon and the water extract of Rhodiola rosea are combined in a weight ratio of 0.5 to 2:1; 2) The aqueous extract of Lithospermum erythrorhizon and the aqueous extract of Glycyrrhiza uralensis are combined in a weight ratio of 0.5 to 2:1; 3) The aqueous extract of Lithospermum erythrorhizon and the aqueous extract of Astragalus membranaceus are combined in a weight ratio of 0.5 to 2:1; 4) The water extracts of Lithospermum erythrorhizon, Rhodiola rosea, and Glycyrrhiza uralensis are combined in a weight ratio of 1 to 2:1:

1. 5) The water extracts of Lithospermum erythrorhizon, Rhodiola rosea, Astragalus membranaceus, and Glycyrrhiza uralensis are combined in a weight ratio of 1:1:1:

1.

3. The composition according to claim 1 or 2, characterized in that, The comfrey oil and the lubricant form a mixture, and the ratio of the emulsifier to the mixture is 1:3 to 7 by weight.

4. The composition according to claim 3, characterized in that, The lubricant is olive oil; the emulsifier is olive oil emulsified wax; the preservative is phenoxyethanol; and the flavoring agent is jasmine essential oil. The composition contains, by weight, 12 parts of comfrey oil, 68 parts of olive oil, 20 parts of olive oil emulsifying wax, 74 parts of comfrey water extract, 74 parts of rhodiola rosea water extract, 74 parts of astragalus water extract, 74 parts of licorice water extract, 4 parts of phenoxyethanol, and 1 part of jasmine essential oil.

5. Use of the composition according to any one of claims 1-4 in the preparation of hand cream.

6. A method for preparing a traditional Chinese medicine moisturizing hand cream, characterized in that, The method includes the following steps: 1) Preparation of extracts from traditional Chinese medicine: The herbal extracts include Lithospermum erythrorhizon extract, or a combination of Lithospermum erythrorhizon extract and other component extracts; The comfrey extract comprises comfrey oil and comfrey aqueous extract; The other component extracts include one, two, or three combinations of Rhodiola rosea water extract, Astragalus membranaceus water extract, and Glycyrrhiza uralensis water extract; The preparation method of the comfrey oil is as follows: By weight, first grind the root of Lithospermum erythrorhizon into powder and pass it through a 40-mesh sieve. Weigh 50g of Lithospermum erythrorhizon powder and place it in an Erlenmeyer flask. Add 200mL of tea tree seed oil. Heat the mixture in a 90℃ constant temperature water bath for 1 hour. After cooling to room temperature, extract it at 4℃ for 2 weeks. After filtration, obtain the Lithospermum erythrorhizon extract. The preparation method of the water extract of Lithospermum erythrorhizon is as follows: Weigh 50g of the filtered Lithospermum erythrorhizon powder after extracting the oily components, add 10 times the amount of distilled water, extract 3 times, 1 hour each time, combine the filtrates and filter to obtain 500mL of Lithospermum erythrorhizon water extract. The preparation method of the Rhodiola rosea water extract is as follows: By weight, the Rhodiola rosea root was ground into powder and passed through a 40-mesh sieve. 50g of Rhodiola rosea powder was weighed and 8 times the amount of distilled water was added. Each extraction was performed for 30 minutes. After 3 extractions, the filtrates were combined and filtered to obtain 500mL of Rhodiola rosea water extract. The preparation method of the Astragalus membranaceus aqueous extract is as follows: By weight, grind the Astragalus root into powder and pass it through a 40-mesh sieve. Weigh 50g of Astragalus powder, add 10 times the amount of distilled water, and extract for 1 hour each time. After 3 extractions, combine the filtrates and filter to obtain 500mL of Astragalus water extract. The method for preparing the licorice water extract is as follows: Grind the licorice root into powder and pass it through a 40-mesh sieve by weight. Weigh 50g of astragalus powder and add 10 times the amount of distilled water. Extract for 1 hour each time. After two extractions, combine the filtrates and filter to obtain 500mL of licorice water extract. 2) Prepare material A, which is the combination of comfrey oil, olive oil and olive oil emulsified wax mentioned in step 1); prepare material B, which is the combination of comfrey water extract, rhodiola rosea water extract, licorice water extract and astragalus water extract mentioned in step 1). 3) Add material B to material A, melt and stir evenly at 80-85℃ to emulsify, and obtain material N; 4) Add preservatives and essential oils to material N, stir well, and cool to room temperature to obtain the hand cream.

7. The method according to claim 6, characterized in that, The herbal extract combination consists of the following parts by weight of traditional Chinese medicine: 12 parts of Lithospermum erythrorhizon oil, 74 parts of Lithospermum erythrorhizon aqueous extract, 74 parts of Rhodiola rosea aqueous extract, 74 parts of Astragalus membranaceus aqueous extract, and 74 parts of Glycyrrhiza uralensis aqueous extract.

8. The method according to claim 6 or 7, characterized in that, The preservative mentioned in step 4) is phenoxyethanol.

9. The method according to claim 6 or 7, characterized in that, Step 4) The essential oil mentioned is jasmine essential oil.

10. The hand cream product prepared by the method according to any one of claims 6-9.

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