Preparation method of saussurea involucrata fermentation product, product of saussurea involucrata fermentation product, preparation bacteria and application

By using mixed fermentation of Bifidobacterium longum subsp. infantis Xue-66, Lactobacillus helveticus Xue-123, and Lactobacillus plantarum PQQ-1, the problem of insufficient inhibition of tyrosinase activity and antioxidant capacity of snow lotus ferment was solved, achieving a more efficient fermentation process and significant whitening and antioxidant effects.

CN120983502AActive Publication Date: 2025-11-21BIO RACE BIOTECH HANGZHOU CO LTD
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Patent Information

Application Number
CN202511511281.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-10-22
Publication Date
2025-11-21
Estimated Expiration
2045-10-22

AI Technical Summary

Technical Problem

In existing technologies, the fermentation products of *Syzygium spp.* are not very effective in inhibiting tyrosinase activity and in terms of antioxidant capacity. Furthermore, most lactic acid bacteria have weak antioxidant capacity, and the fermentation process and metabolic mechanisms are not sufficiently explored, resulting in suboptimal safety and efficacy of the fermented products.

Method used

A mixture of Bifidobacterium longum subsp. infantis Xue-66, Lactobacillus helveticus Xue-123, and Lactobacillus plantarum PQQ-1 was used for fermentation. Collagen, whey protein, and lactose were used as substrates. The fermentation temperature and speed were controlled, and the fermented product of Saussurea involucrata was separated by centrifugation and filtration.

Benefits of technology

It significantly improves fermentation efficiency, significantly inhibits tyrosinase activity, has whitening effects, and induces collagen synthesis at lower concentrations, increasing skin elasticity and exhibiting significant antioxidant capacity.

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Abstract

The invention provides a preparation method of a saussurea involucrata fermentation product, a product of the saussurea involucrata fermentation product, preparation bacteria and application, and belongs to the field of microbial fermentation. The invention provides new strains, namely Bifidobacterium longum subsp. Infantis Xue-66 and Lactobacillus helveticus Xue-123, which are separated from a saussurea involucrata flora, and after the Bifidobacterium longum subsp. Infantis Xue-66, the Lactobacillus helveticus Xue-123 and the Lactobacillus plantarum PQQ-1 are subjected to co-fermentation with whey protein and collagen, the separated metabiotics are called as a saussurea involucrata fermentation product. The saussurea involucrata fermentation product has the capabilities of remarkably inhibiting the activity of tyrosinase and inhibiting the gene expression of tyrosinase, has a remarkable whitening effect, and can effectively improve the skin elasticity.
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