Protein peptide particles for special diet based on multi-component proportion and production process thereof

By using a multi-component ratio and concentration production process based on the theory of traditional Chinese medicine, special dietary protein peptide granules are prepared, which solves the problems of reduced efficacy and long preparation cycle of traditional Chinese medicine formula granules, and achieves maximum efficacy and improved production efficiency.

CN120983560APending Publication Date: 2025-11-21CHANGSHOU TIMES (ZIBO) BIOMEDICAL HEALTH IND DEVELOPMENT CO LTD
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Patent Information

Application Number
CN202511254407.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-09-04
Publication Date
2025-11-21

AI Technical Summary

Technical Problem

The traditional Chinese medicine formula granule preparation process completely abandons the formulation principles in the Chinese medicine theory system, resulting in reduced efficacy. In addition, following the formulation principles in the Chinese medicine theory system would greatly prolong the preparation cycle.

Method used

A special dietary protein peptide granule production process based on multi-component ratios was adopted. Combining the formulation principles of traditional Chinese medicine theory, protein peptide granules of fifteen Chinese medicinal herbs, including Solomon's seal, Poria cocos, licorice, and American ginseng, were prepared through multi-component ratios and concentration production processes. The process included material pretreatment, first juice extraction and concentration, second juice extraction and concentration, and pilot production was carried out using a paste collection device.

Benefits of technology

While maximizing efficacy, the preparation cycle was significantly shortened, and production efficiency was improved while energy consumption was reduced.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of particle product preparation, in particular to special dietary protein peptide particles based on multi-component proportioning and a production process thereof, the particles are prepared from radix polygonati officinalis, poria cocos, liquorice, hawthorn, American ginseng, radix puerariae, exocarpium citri grandis, radix ophiopogonis, Chinese yam, codonopsis pilosula, astragalus membranaceus, dogwood, gastrodia elata, peach kernels and oysters. The process comprises the following steps: soaking the fifteen raw materials, extracting, concentrating, drying, crushing, granulating, finishing, totally mixing and packaging. According to the protein peptide particles for the special diet based on the multi-component proportion and the production process of the protein peptide particles, on the basis of the formula principle in a traditional Chinese medicine theoretical system, the medicine effect is kept to be maximized, and the preparation period is shortened.
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Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of granular product preparation, in particular to special dietary protein peptide granules based on multi-component proportioning and a production process thereof. BACKGROUND

[0002] Traditional Chinese medicine is the medical wisdom accumulated by the Chinese nation over thousands of years, using natural plants, animals and minerals as the basis of drug components, guided by unique theoretical systems such as yin and yang, five elements, monarch, minister, assistant and messenger, to guide the prevention and treatment of diseases. Traditional Chinese medicine technology covers multiple links such as planting, processing, extraction and preparation of medicinal materials.

[0003] At present, based on the theory of traditional Chinese medicine in the field of medicine, with the development of modern science and technology, traditional Chinese medicine liquid has made breakthroughs in the three dimensions of standardization, scientization and internationalization, and traditional Chinese medicine is also constantly optimized and developed towards health care, and the important concept of "medicinal food" in traditional Chinese medicine theory is proposed. Substances that can be eaten daily are used as medicines to regulate diseases, embodying the health preservation concept of "preventive treatment". This is also the wisdom of traditional Chinese medicine theory that is increasingly valued in the modern health industry and becomes an important direction for the research and development of functional foods and health products.

[0004] Traditional Chinese medicine preparation has limitations such as complicated decoction, inaccurate dosage and inconvenient storage. In view of the shortcomings of traditional Chinese medicine preparation, traditional Chinese medicine formula granules have the characteristics of easy decoction, accurate dosage and convenient storage, and therefore have arisen and developed, and are also more recognized by users and the market.

[0005] However, in the conventional preparation process of traditional Chinese medicine formula granules, the following technical problems still exist:

[0006] 1. The prescription principles in the theoretical system of traditional Chinese medicine are completely abandoned, reducing the efficacy;

[0007] 2. If the prescription principles in the theoretical system of traditional Chinese medicine are followed, the preparation period will be greatly prolonged. SUMMARY

[0008] In order to solve the technical problems in the background art, the present application provides special dietary protein peptide granules based on multi-component proportioning and a production process thereof, which maintains maximum efficacy and shortens the preparation period on the basis of the prescription principles in the theoretical system of traditional Chinese medicine.

[0009] The technical solution adopted by the present application is:

[0010] The special dietary protein peptide granules based on multi-component proportioning, the formula composition of the preparation raw materials of the protein peptide granules comprises:

[0011] 10-20g of polygonatum, 8-15g of tuckahoe, 3-8g of licorice, 10-18g of hawthorn and 3-8g of western ginseng

[0012] Radix Paeoniae 10-18g Citrus aurantium 3-8g Ophiopogon japonicus 6-15g Dioscorea opposita 12-20g Radix Codonopsis 8-18g

[0013] Radix Astragali 12-18g Fructus Corni 12-18g Gastrodia 8-15g Semen Persicae 8-15g Concha Molluscorum 12-20g.

[0014] Further, the above fifteen kinds of raw materials are prepared in the following proportions:

[0015] Group A: Proportions:

[0016] Lord: Panacis Quinquefolii Radix 3-8g; Vassal: Ophiopogonis Radix 2-5g; Assistant: Astragali Radix 4-8g; Make: Paeoniae Radix 2-4g;

[0017] Group B: Proportions:

[0018] Lord: Tuckahoe 8-15g; Vassal: Dioscorea opposita 10-16g; Assistant: Crataegus pinnatifida 4-6g; Make: Codonopsis 8-18g;

[0019] Group C: Proportions:

[0020] Lord: Citrus aurantium 3-8g; Vassal: Semen Persicae 8-15g; Assistant: Astragali Radix 8-10g; Make: Crataegus pinnatifida 6-12g;

[0021] Group D: Proportions:

[0022] Lord: Fructus Corni 12-18g; Vassal: Gastrodia 8-15g; Assistant: Concha Molluscorum 12-20g; Make: Dioscorea opposita 2-4g;

[0023] Group E: Proportions:

[0024] Lord: Polygonatum 10-20g; Vassal: Ophiopogonis Radix 4-10g; Assistant: Glycyrrhiza 3-8g; Make: Paeoniae Radix 8-14g.

[0025] The concentrated production process of the special dietary protein peptide particles based on multiple component proportions includes:

[0026] S21, material pretreatment:

[0027] “Polygonatum, Tuckahoe, Glycyrrhiza, Crataegus pinnatifida, Paeoniae Radix, Citrus aurantium, Ophiopogonis Radix, Dioscorea opposita, Astragali Radix, Fructus Corni, Gastrodia, Semen Persicae, Concha Molluscorum”, and “Panacis Quinquefolii Radix, Codonopsis” after breaking the wall, are weighed and bagged for standby;

[0028] S22, first juice extraction:

[0029] The bagged material is put into the soaking bottle, and six times the weight of drinking water is injected for soaking, and then water bath is kept;

[0030] S23, first juice concentrate collection:

[0031] Start the vacuum concentrator, and extract the first juice extract in the soaking bottle into the vacuum concentrator. Turn on the heating disc to concentrate the first juice extract into the first juice concentrate.

[0032] S24, second juice extraction:

[0033] Pour four times the weight of drinking water into the soaking bottle for soaking, and then perform water bath heat preservation.

[0034] S25, second juice concentrate collection:

[0035] Start the vacuum concentrator, and extract the second juice extract in the soaking bottle into the vacuum concentrator and mix it with the first juice concentrate. Turn on the heating disc to concentrate the first juice concentrate and the first juice extract into the second juice concentrate.

[0036] The production process of the special dietary protein peptide granules based on multiple component allocation ratios, the concentration process in the production process, and the collection equipment for pilot production, the collection equipment comprising:

[0037] The soaking tank, the filter, the extraction tank, the concentration tank, the buffer tank, and the condenser are arranged on the pry frame, and the recovery tank is arranged on one side of the pry frame.

[0038] A sight glass feeding port is arranged at the upper end of the soaking tank, and a soaking liquid discharge port is arranged at the lower end of the soaking tank. A circulating pump is arranged in the pipeline of the soaking liquid discharge port. The outlet of the circulating pump is connected to the upper end of the soaking tank and the upper end of the filter through a three-way pipe. A filter liquid discharge port is arranged at the lower end of the filter. The pipeline of the filter liquid discharge port is connected to the extraction tank. An extraction liquid discharge port is arranged at the lower end of the extraction tank. The pipeline of the extraction liquid discharge port is connected to the concentration tank. A concentration paste discharge port is arranged at the lower end of the concentration tank. An exhaust port is arranged at the upper end of the extraction tank and the concentration tank. The exhaust port is connected to the tube inlet of the condenser. The tube outlet of the condenser is connected to the recovery tank. A sight tube is arranged at the recovery tank discharge port. The lower end of the sight tube is connected to the upper end of the extraction tank, the upper end of the concentration tank, and the upper end of the buffer tank through a U-shaped pipe. The upper end of the buffer tank is connected to the vacuum unit. A recovery liquid discharge port is arranged at the lower end of the buffer tank. The pipeline of the recovery liquid discharge port is connected to the upper end of the recovery tank. A tank pump is arranged in the recovery tank.

[0039] The soaking tank, the extraction tank, and the concentration tank are provided with heating jackets.

[0040] The buffer tank and the recovery tank are provided with cooling jackets. The shell of the cooling jacket and the condenser is connected to the circulating pipeline of the refrigerant.

[0041] Further, the pipeline of the filter filtrate discharge port is communicated with a tee pipe, and is communicated with the extraction tank and the concentration tank respectively.

[0042] Further, the pilot production of the production process comprises:

[0043] S31, material pretreatment:

[0044] Prepare materials according to 2000 people / batch;

[0045] “Yu zhu, Fuling, Gancao, Shanhua, Gegen, Huazao, Maidou, Shanyao, Huangqi, Shanzhu, Tianma, Taoren, Muli”, and “Xiyangshen, Dangshen” after breaking the wall, double weighing and rechecking and bagging for standby;

[0046] S321, first juice extraction:

[0047] Put the bagged material into the immersion liquid tank, and inject six times the weight of drinking water for soaking;

[0048] Heat preservation is carried out through the spacer, and the circulating pump is started and the liquid level in the immersion liquid tank is ensured to be higher than the material bag;

[0049] S322, first juice concentration and paste collection:

[0050] The first juice extraction liquid in the immersion liquid tank is sent to the extraction tank through the filter by the circulating pump and / or vacuum unit;

[0051] The first juice extraction liquid in the extraction tank is concentrated into first juice concentrated paste under vacuum state by heating through the spacer;

[0052] Water vaporization is condensed in sequence through the tube of the condenser, the recovery tank, the sight pipe and the buffer tank from the exhaust port of the extraction tank, until the condensed water is collected in the buffer tank under vacuum state;

[0053] The first juice concentrated paste in the extraction tank is extracted into the concentration tank by the vacuum unit;

[0054] S331, second juice extraction:

[0055] Inject four times the weight of drinking water into the immersion liquid tank for soaking;

[0056] Heat preservation is carried out through the spacer, and the circulating pump is started and the liquid level in the immersion liquid tank is ensured to be higher than the material bag;

[0057] S332, second juice concentration and paste collection:

[0058] The second juice extraction liquid in the immersion liquid tank is extracted and sent to the concentration tank through the filter by the circulating pump and vacuum unit, and is mixed with the first juice concentrated paste in the concentration tank;

[0059] Heating by the spacer, the first juice concentrate paste and the second juice extract concentrate in the vacuum state are concentrated into the second juice concentrate paste in the concentration tank;

[0060] The water vaporization is condensed in sequence through the pipe passage of the condenser, the recovery tank, the sight tube and the buffer tank from the exhaust port of the concentration tank, until the condensed water is collected in the buffer tank in the vacuum state.

[0061] Further, the production process includes:

[0062] S41, material pretreatment:

[0063] The materials are prepared according to 8000 servings / batch;

[0064] The broken "American ginseng", and "Ophiopogon, Astragalus, Pueraria", are respectively double-weighed and rechecked, and are loaded into A group formula material bag for standby;

[0065] The broken "Dangshen", and "Tuckahoe, Yam, Hawthorn", are respectively double-weighed and rechecked, and are loaded into B group formula material bag for standby;

[0066] "Orange peel, peach kernel, astragalus, hawthorn", are double-weighed and rechecked, and are loaded into C group formula material bag for standby;

[0067] "Amomum villosum, Gastrodia, Oyster, Yam", are double-weighed and rechecked, and are loaded into D group formula material bag for standby;

[0068] "Polygonatum, Ophiopogon, Licorice, Pueraria", are double-weighed and rechecked, and are loaded into E group formula material bag for standby;

[0069] S42, formula extraction and paste collection:

[0070] The formula material bag is put into the immersion tank, and six times the weight of drinking water is injected for soaking. The circulating pump is started under heat preservation to circulate the soaking liquid;

[0071] The formula first juice extract in the immersion tank is transported and / or pumped to the extraction tank through the filter. The formula first juice extract in the extraction tank under vacuum is heated and concentrated into the formula first juice concentrate paste. The formula first juice concentrate paste in the extraction tank is pumped into the concentration tank;

[0072] Four times the weight of drinking water is injected into the immersion tank for soaking. The circulating pump is started under heat preservation to circulate the soaking liquid. The formula second juice extract in the immersion tank is pumped to the concentration tank through the filter and mixed with the formula first juice concentrate paste in the concentration tank. The formula first juice concentrate paste and the formula second juice extract in the concentration tank under vacuum are heated and concentrated into the formula second juice concentrate paste;

[0073] Any one of the A group formula material bag, the B group formula material bag, the C group formula material bag, the D group formula material bag, the E group formula material bag is respectively put into the immersion liquid tank, and the A group formula second juice concentrated paste, the B group formula second juice concentrated paste, the C group formula second juice concentrated paste, the D group formula second juice concentrated paste, the E group formula second juice concentrated paste are respectively prepared;

[0074] S43, paste mixing:

[0075] The A group formula second juice concentrated paste, the B group formula second juice concentrated paste, the C group formula second juice concentrated paste, the D group formula second juice concentrated paste, the E group formula second juice concentrated paste are mixed.

[0076] Further, the production process includes:

[0077] S51, material pretreatment:

[0078] The materials are prepared according to 4000 servings / batch;

[0079] The broken wall “American ginseng”, and “magnolia, astragalus, pueraria” are respectively double-weighed and rechecked, and are loaded into the A group formula material bag for standby;

[0080] The broken wall “dangshen”, and “tuckahoe, yam, hawthorn” are respectively double-weighed and rechecked, and are loaded into the B group formula material bag for standby;

[0081] “Huazhuhong, peach kernel, astragalus, hawthorn” are double-weighed and rechecked, and are loaded into the C group formula material bag for standby;

[0082] “Shanzhuyi, Tianma, Oyster, yam” are double-weighed and rechecked, and are loaded into the D group formula material bag for standby;

[0083] “Yuzhu, magnolia, licorice, pueraria” are double-weighed and rechecked, and are loaded into the E group formula material bag for standby;

[0084] S521, first juice extraction of three groups and first juice concentrated paste of three groups:

[0085] The A group formula material bag, the B group formula material bag, the C group formula material bag are put into the immersion liquid tank, and six times the weight of drinking water is injected into the immersion liquid tank for immersion, and the circulating pump is started under heat preservation state to circulate the immersion liquid;

[0086] The three group first juice extraction liquid in the immersion liquid tank is transported and / or pumped to the extraction tank through the filter;

[0087] The three group first juice extraction liquid in the extraction tank is heated and concentrated into three group first juice concentrated paste under vacuum state;

[0088] The three group first juice concentrated paste in the extraction tank is pumped into the concentration tank;

[0089] S522, second juice extraction of the three groups and second juice concentration of the three groups:

[0090] The liquid infusion tank is injected with four times the weight of drinking water for infusion, and the circulating pump is started under the condition of heat preservation to circulate the infusion liquid;

[0091] The second juice extraction liquid of the three groups in the liquid infusion tank is pumped to the concentration tank through the filter and mixed with the first juice concentrated paste of the three groups in the concentration tank;

[0092] The first juice concentrated paste of the three groups and the second juice extraction liquid in the concentration tank under vacuum are heated and concentrated into the second juice concentrated paste of the three groups;

[0093] S531, first juice extraction of the two groups and first juice concentration of the five groups:

[0094] The liquid infusion tank is injected with six times the weight of drinking water for infusion, and the circulating pump is started under the condition of heat preservation to circulate the infusion liquid;

[0095] The first juice extraction liquid of the two groups in the liquid infusion tank is transported and / or pumped to the extraction tank through the filter;

[0096] The first juice extraction liquid of the two groups in the extraction tank under vacuum is heated and concentrated into the first juice concentrated paste of the two groups;

[0097] The first juice concentrated paste of the two groups in the extraction tank is pumped into the concentration tank and mixed with the second juice concentrated paste of the three groups;

[0098] The second juice concentrated paste of the three groups and the first juice extraction liquid in the concentration tank under vacuum are heated and concentrated into the first juice concentrated paste of the five groups;

[0099] S532, second juice extraction of the two groups and second juice concentration of the five groups:

[0100] The liquid infusion tank is injected with four times the weight of drinking water for infusion, and the circulating pump is started under the condition of heat preservation to circulate the infusion liquid;

[0101] The second juice extraction liquid of the two groups in the liquid infusion tank is pumped to the concentration tank through the filter and mixed with the first juice concentrated paste of the five groups in the concentration tank;

[0102] The first juice concentrated paste of the five groups and the second juice extraction liquid in the concentration tank under vacuum are heated and concentrated into the second juice concentrated paste of the five groups.

[0103] Further, the pilot production of the production process is four uses to reduce the energy consumption in production, including:

[0104] The step S521, the first juice extraction of the three groups and the first juice concentration and paste collection of the three groups:

[0105] The concentration temperature of the first juice concentrated paste of the three groups is reduced, and the concentration period of the first juice concentrated paste of the three groups is prolonged by using the stage temperature control, so that the second juice extraction of the three groups is carried out;

[0106] The step S522, the second juice extraction of the three groups and the second juice concentration and paste collection of the three groups:

[0107] The concentration temperature of the second juice concentrated paste of the three groups is reduced, and the concentration period of the second juice concentrated paste of the three groups is prolonged by using the stage temperature control, so that the first juice extraction of the two groups is carried out, and the mixed second juice extraction liquid of the three groups and the first juice concentrated liquid of the three groups are simultaneously heated and concentrated;

[0108] The step S531, the first juice extraction of the two groups and the first juice concentration and paste collection of the five groups:

[0109] The concentration temperature of the first juice concentrated paste of the two groups is reduced, and the concentration period of the first juice concentrated paste of the two groups is prolonged by using the stage temperature control, so that the second juice extraction of the two groups is carried out respectively;

[0110] The concentration temperature of the first juice concentrated paste of the five groups is maintained, and the mixed second juice concentrated liquid of the three groups and the first juice extraction liquid of the two groups are simultaneously heated and concentrated;

[0111] The step S532, the second juice extraction of the two groups and the second juice concentration and paste collection of the five groups:

[0112] The concentration temperature of the second juice concentrated paste of the five groups is maintained, and the mixed first juice concentrated liquid of the five groups and the second juice extraction liquid of the two groups are simultaneously heated and concentrated, and the concentration is completed by using the waste heat.

[0113] The present application is based on the beneficial effects of the special dietary protein peptide particles with multiple distribution ratios and the production process thereof:

[0114] 1. The concentrated paste output is verified in the small test stage;

[0115] 2. The production period and output efficiency of the first, second and third pilot productions are compared, so as to ensure the optimization of the pilot production;

[0116] 3. On the basis of the third pilot production, the process parameters of the fourth pilot production are adjusted to ensure the production period and output efficiency of the third pilot production, and at the same time, the production energy consumption is reduced. BRIEF DESCRIPTION OF DRAWINGS

[0117] Figure 1 is the front view schematic diagram of the paste collection equipment of the present application example;

[0118] Figure 2 is a right view schematic diagram of the cream collecting equipment of the present application.

[0119] In the figure:

[0120] 11, immersion liquid tank, 12, filter, 13, extraction tank, 14, concentration tank, 15, buffer tank,

[0121] 21, condenser, 22, recovery tank, 23, sight tube,

[0122] 30, circulating pump,

[0123] 40, recovery tank. DETAILED DESCRIPTION

[0124] In order to more clearly and explicitly illustrate the specific implementation purposes and implementation manners of the present application, the technical solutions of the present application will be described in detail below, and the described embodiments are part of the embodiments of the present application, rather than all the embodiments. Based on the described embodiments of the present application, all other embodiments within the scope of protection of the present application belong to the present application without creative labor.

[0125] The present application is based on special dietary protein peptide particles with multiple dispensing ratios, and the preparation raw material dosage ratio is:

[0126] 10-20g of polygonatum, 8-15g of tuckahoe, 3-8g of licorice, 10-18g of hawthorn, 3-8g of western ginseng

[0127] 10-18g of pueraria, 3-8g of citrus unshiu peel, 6-15g of ophiopogon, 12-20g of Chinese yam, 8-18g of dangshen

[0128] 12-18g of astragalus, 12-18g of dogwood, 8-15g of gastrodia, 8-15g of peach kernel, 12-20g of oyster.

[0129] The first stage of the small test includes:

[0130] S11, material pretreatment:

[0131] “polygonatum, tuckahoe, licorice, hawthorn, pueraria, citrus unshiu peel, ophiopogon, Chinese yam, astragalus, dogwood, gastrodia, peach kernel, oyster” are weighed and bagged for standby.

[0132] The “western ginseng, dangshen” after breaking the wall are weighed and bagged for standby.

[0133] S12, extraction:

[0134] Put the bagged "Polygonatum, Poria cocos, licorice, hawthorn, kudzu, Citrus aurantium, Ophiopogon, Chinese yam, Astragalus, dogwood, Gastrodia, peach kernel, oyster" and "western ginseng, Dangshen" into the soaking bottle, and add six times the weight of drinking water into the soaking bottle and soak for at least 40h.

[0135] S13, concentrate and collect the extract:

[0136] Start the vacuum concentrator, open the vacuum pump until the vacuum pressure is 0.06MPa, open the feeding valve to pump the extract in the soaking bottle into the vacuum concentrator, and open the heating disc to concentrate the extract.

[0137] The concentration temperature is ≤70℃, and the extract is concentrated to a specific gravity of 1.08-1.18.

[0138] The preparation process of Citrus aurantium in the raw materials includes:

[0139] Weigh the batch amount of Citrus aurantium and put it into the volatile oil extraction tank, and add ten times the amount of drinking water and soak for 12h; under vacuum, steam jacket heating of the soaking liquid of Citrus aurantium until boiling, Citrus aurantium is distilled and extracted, the steam pressure is 0.15-0.2Mpa, the soaking liquid temperature is 100℃, and the distillation extraction time is 7h; the volatile oil of Citrus aurantium is collected by condenser after distillation, and separated by oil-water separator, the volatile oil floating on the surface is separated and reserved, and the volatile oil extraction yield of Citrus aurantium should be ≥1%.

[0140] Weigh the batch amount of Citrus aurantium volatile oil, and the same amount of 95% ethanol, eight times the amount of β-CD, and sixteen times the amount of purified water; stir and mix the Citrus aurantium volatile oil and ethanol thoroughly; add purified water to a clean container and heat in water bath to 40℃, stir and add β-CD until fully dissolved, stir and add the mixture of Citrus aurantium volatile oil and ethanol until fully dissolved; pour the dissolved liquid into a stirring tank and continue to stir, the temperature of the dissolved liquid is ≤40℃, and the stirring time is ≥2h; the stirred dissolved liquid is placed for ≥12h; the placed dissolved liquid is filtered, and the filtered liquid is poured into a vacuum drying oven for drying, the drying temperature is 35-40℃, and the drying time is 4-5h; the dried material is crushed through a 60 mesh sieve; the crushed material is mixed by a multidirectional three-dimensional motion mixer, the mixing speed is 8-10Hz, and the mixing time is 10min, and the Citrus aurantium inclusion compound is prepared.

[0141] The second stage of the small test includes:

[0142] S21, material pretreatment:

[0143] "Polygonatum, Poria cocos, licorice, hawthorn, kudzu, Citrus aurantium, Ophiopogon, Chinese yam, Astragalus, dogwood, Gastrodia, peach kernel, oyster", are weighed and bagged for use.

[0144] After breaking the wall, "American ginseng, Dangshen" is weighed and packed for use.

[0145] S22, first juice extraction:

[0146] The bagged "Yujin, Fuling, Gancao, Shanzha, Gegen, Huazao, Maidou, Shanyao, Huangqi, Shanzhu, Tianma, Taoren, Muli" and "American ginseng, Dangshen" are placed in the soaking bottle, and six times the weight of drinking water is added to the soaking bottle and soaked for at least 24 hours.

[0147] S23, first juice concentration and paste collection:

[0148] Start the vacuum concentrator, turn on the vacuum pump until the vacuum pressure is 0.06 MPa, open the feed valve to extract the first juice extract in the soaking bottle into the vacuum concentrator, and open the heating disc to concentrate the first juice extract.

[0149] The concentration temperature is ≤70℃, and the first juice concentrate is concentrated to a specific gravity of 1.08-1.14.

[0150] S24, second juice extraction:

[0151] To the soaking bottle containing bagged "Yujin, Fuling, Gancao, Shanzha, Gegen, Huazao, Maidou, Shanyao, Huangqi, Shanzhu, Tianma, Taoren, Muli" and "American ginseng, Dangshen", add four times the weight of drinking water and soak for at least 24 hours.

[0152] The soaking bottle is kept warm by the water bath constant temperature device for 2 hours, and the temperature is ≤70℃.

[0153] S25, second juice concentration and paste collection:

[0154] Start the vacuum concentrator, turn on the vacuum pump until the vacuum pressure is 0.06 MPa, open the feed valve to extract the second juice extract in the soaking bottle into the vacuum concentrator, and mix with the first juice concentrate, open the heating disc to concentrate the mixed first juice concentrate and second juice extract.

[0155] The concentration temperature is ≤70℃, and the second juice concentrate is concentrated to a specific gravity of 1.14-1.18.

[0156] In the mode of the first stage of the test: the weight of the fifteen kinds of materials is 110g-212g, the water absorption rate of the fifteen kinds of materials is 1.5, after adding six times the weight of drinking water, the amount of extract is 495-954g, and the amount of concentrate with a specific gravity of 1.08-1.18 is 420-887g.

[0157] In the mode of the second small test stage: the weight of the fifteen ingredients is 110g-212g, the water absorption rate of the fifteen ingredients during the first juice extraction is 1.5, after adding six times the weight of drinking water, the first juice extraction liquid is 495-954g, the specific gravity is 1.08-1.14, the first juice concentrated paste is 420-840g; the water absorption rate of the fifteen ingredients during the second juice extraction is 0.75, after adding four times the weight of drinking water, the second juice extraction liquid is 357-610g; the mixed liquid of the first juice concentrated paste and the second juice extraction liquid is 777-1450g, the specific gravity is 1.14-1.18, and the second juice concentrated paste is 620-1255g.

[0158] Table 1 is the comparison of the output parameters of the first small test stage and the second small test stage:

[0159]

[0160] Although the total output period in the second small test stage is longer than that in the first small test stage, the total extraction period of the first juice extraction liquid and the second juice extraction liquid in the second small test stage is shorter than that of the extraction liquid in the first small test stage, the output of the second juice concentrated paste in the second small test stage is more than that of the concentrated paste in the first small test stage, and the extraction period of the second small test stage is shorter, the concentration rate is higher, and the output efficiency is higher.

[0161] On the basis of the small test verification, a pilot production is carried out through a concentration equipment, and the concentration equipment, as shown in Figure 1 、 Figure 2 includes:

[0162] The immersion liquid tank 11, the filter 12, the extraction tank 13, the concentration tank 14, the buffer tank 15, and the condenser 21 are arranged on the pry frame, and the recovery tank 40 is arranged on one side of the pry frame.

[0163] The upper end of the immersion liquid tank 11 is provided with a sight glass feeding port, and the lower end of the immersion liquid tank 11 is provided with an immersion liquid discharge port in the center. A circulating pump 30 is connected to the pipeline of the immersion liquid discharge port. The outlet of the circulating pump 30 is connected to the upper end of the immersion liquid tank 11 and the upper end of the filter 12 through a three-way pipe. The lower end of the filter 12 is provided with a filtered liquid discharge port in the center. The pipeline of the filtered liquid discharge port is connected to the extraction tank 13. The lower end of the extraction tank 13 is provided with an extraction liquid discharge port in the center. The pipeline of the extraction liquid discharge port is connected to the concentration tank 14. The lower end of the concentration tank 14 is provided with a concentrated paste discharge port in the center. The upper end of the extraction tank 13 and the upper end of the concentration tank 14 are provided with an exhaust port in the center. The exhaust port is connected to the pipe inlet of the condenser 21. The pipe outlet of the condenser 21 is connected to the recovery tank 22. The discharge port of the recovery tank 22 is connected to the sight tube 23. The lower end of the sight tube 23 is connected to the upper end of the extraction tank 13, the upper end of the concentration tank 14, and the upper end of the buffer tank 15 through a U-shaped pipe. The upper end of the buffer tank 15 is connected to the vacuum unit and maintains a vacuum pressure of 0.06 MPa. The lower end of the buffer tank 15 is provided with a recovery liquid discharge port in the center. The pipeline of the recovery liquid discharge port is connected to the upper end of the recovery tank 40. The recovery tank 40 is provided with an in-tank pump.

[0164] The immersion liquid tank 11, the extraction tank 13, and the concentration tank 14 are provided with heating jackets. The buffer tank 15 and the recovery tank 22 are provided with cooling jackets. The shell side of the cooling jacket and the condenser 21 is connected to the circulating pipeline of the refrigerant.

[0165] The pilot production I includes:

[0166] S31, material pretreatment:

[0167] Prepare materials according to 2000 servings / batch.

[0168] “Jade bamboo, tuckahoe, licorice, hawthorn, kudzu root, orange peel, ophiopogon, yam, astragalus, dogwood, Gastrodia, peach kernel, oyster shell”, double weighing and rechecking are performed, and bags are prepared for use.

[0169] After breaking the wall, “American ginseng, dangshen”, double weighing and rechecking are performed, and bags are prepared for use.

[0170] S321, first juice extraction:

[0171] Put the bagged “jade bamboo, tuckahoe, licorice, hawthorn, kudzu root, orange peel, ophiopogon, yam, astragalus, dogwood, Gastrodia, peach kernel, oyster shell” and “American ginseng, dangshen” into the immersion liquid tank 11 from the sight glass feeding port. Add six times the weight of drinking water in the recovery tank 40 into the immersion liquid tank 11 through the in-tank pump, and soak for at least 12 h.

[0172] The circulating hot water is introduced into the heating jacket of the immersion tank 11 for 2 hours for heat preservation, the heat preservation temperature is less than or equal to 70 DEG C, the circulating pump 30 is started, and the liquid level in the immersion tank 11 is observed through the sight glass, and the liquid level in the immersion tank 11 is kept higher than the material bag.

[0173] S322, the first juice is concentrated and collected:

[0174] The first juice extract in the immersion tank 11 is transported to the extraction tank 13 through the filter 12 by the circulating pump 30 and / or connecting the extraction tank 13 with the buffer tank 15 in a vacuum state.

[0175] The extraction tank 13 is connected with the buffer tank 15 in a vacuum state through the tube of the condenser 21 and the recovery tank 22, so that the vacuum state of the extraction tank 13 is maintained, the circulating hot water is introduced into the heating jacket of the extraction tank 13 for concentration, the first juice concentrate with a specific gravity of 1.08-1.14 is obtained, the concentration period is 6-8 hours, and the concentration temperature is less than or equal to 70 DEG C.

[0176] The water vaporization is condensed in sequence through the tube of the condenser 21, the recovery tank 22, the sight tube 23 and the buffer tank 15 from the exhaust port of the extraction tank 13, and the condensed water is collected in the buffer tank 15 in a vacuum state.

[0177] The concentrated tank 14 is connected with the buffer tank 15 in a vacuum state, and the first juice concentrate in the extraction tank 13 is pumped into the concentrated tank 14.

[0178] S331, the second juice is extracted:

[0179] The four times weight of drinking water in the recovery tank 40 is added to the immersion tank 11 by the in-tank pump, and soaked for at least 12 hours.

[0180] The circulating hot water is introduced into the heating jacket of the immersion tank 11 for 2 hours for heat preservation, the heat preservation temperature is less than or equal to 70 DEG C, the circulating pump 30 is started, and the liquid level in the immersion tank 11 is observed through the sight glass, and the liquid level in the immersion tank 11 is kept higher than the material bag.

[0181] S332, the second juice is concentrated and collected:

[0182] The second juice extract in the immersion tank 11 is transported to the concentrated tank 14 in sequence through the filter 12 and the extraction tank 13 by the circulating pump 30 and connecting the concentrated tank 14 with the buffer tank 15 in a vacuum state, and mixed with the first juice concentrate in the concentrated tank 14.

[0183] The condensed tank 14 is connected to the pipe passage of the condenser 21, the recovery tank 22 and the buffer tank 15 in vacuum state, so as to keep the vacuum state of the condensed tank 14, and the circulating hot water is introduced into the heating jacket of the condensed tank 14 to concentrate, and the second juice concentrate with specific gravity of 1.14-1.18 is obtained after concentration for 3-4h at temperature of ≤70℃.

[0184] The water vaporization is condensed by the exhaust port of the condensed tank 14 in sequence through the pipe passage of the condenser 21, the recovery tank 22, the sight pipe 23 and the buffer tank 15 in vacuum state, and the condensed water is collected in the buffer tank 15 in vacuum state.

[0185] The pipeline of the filtrate discharge port of the filter 12 in the concentrate equipment is connected with the three-way pipe fitting, and is connected with the extraction tank 13 and the condensed tank 14 respectively.

[0186] According to the "monarch, minister, assistant and messenger" prescription principle of traditional Chinese medicine, grouping is carried out, and pilot production is carried out.

[0187] According to the distribution mode of the "monarch, minister, assistant and messenger" prescription principle, the above fifteen kinds of preparation raw materials are prepared by the following amount ratio:

[0188] Group A: prescription ratio:

[0189] Monarch: American ginseng 3-8g; Minister: Ophiopogon 2-5g; Assistant: Astragalus 4-8g; Messenger: Pueraria 2-4g.

[0190] Group B: prescription ratio:

[0191] Monarch: Tuckahoe 8-15g; Minister: Yam 10-16g; Assistant: Hawthorn 4-6g; Messenger: Dangshen 8-18g.

[0192] Group C: prescription ratio:

[0193] Monarch: Citrus grandis 3-8g; Minister: Peach kernel 8-15g; Assistant: Astragalus 8-10g; Messenger: Hawthorn 6-12g.

[0194] Group D: prescription ratio:

[0195] Monarch: Dogwood 12-18g; Minister: Gastrodia 8-15g; Assistant: Oyster 12-20g; Messenger: Yam 2-4g.

[0196] Group E: prescription ratio:

[0197] Monarch: Polygonatum 10-20g; Minister: Ophiopogon 4-10g; Assistant: Licorice 3-8g; Messenger: Pueraria 8-14g.

[0198] The second pilot production includes:

[0199] S41, material pretreatment:

[0200] Prepare the materials in 8000 servings per batch.

[0201] After breaking the wall, "American ginseng, dangshen", double weighing and rechecking, and packing separately for standby.

[0202] "Dongdong, Huangqi, Gegen", double weighing and rechecking, and packed with "American ginseng" into A group of material bags for standby.

[0203] "Fuling, Shanyao, Shanzha", double weighing and rechecking, and packed with "Dangshen" into B group of material bags for standby.

[0204] "Huazao, Tao Ren, Huangqi, Shanzha", double weighing and rechecking, and packed into C group of material bags for standby.

[0205] "Shanzhu, Tianma, Muli, Shanyao", double weighing and rechecking, and packed into D group of material bags for standby.

[0206] "Yuzhu, Maidong, Gancao, Gegen", double weighing and rechecking, and packed into E group of material bags for standby.

[0207] S42, prescription extraction and collection of paste:

[0208] The first juice of the prescription is extracted in the immersion tank 11; the amount of drinking water is six times the weight of the prescription, and is soaked for at least 12h; the immersion tank 11 is kept warm for 2h and circulated, and the warm temperature is ≤70℃; the first juice of the prescription extraction is transported and / or pumped into the extraction tank 13, and is heated and concentrated, and the concentrated paste of the first juice of the prescription is concentrated to a specific gravity of 1.08-1.14, the concentration period is 8-10h, and the concentration temperature is ≤70℃; the concentrated paste of the first juice of the prescription is pumped into the concentration tank 14.

[0209] The second juice of the prescription is extracted in the immersion tank 11; the amount of drinking water is four times the weight of the prescription, and is soaked for at least 12h; the immersion tank 11 is kept warm for 2h and circulated, and the warm temperature is ≤70℃; the second juice of the prescription extraction is pumped into the concentration tank 14, and is mixed with the concentrated paste of the first juice of the prescription, and is heated and concentrated, and the concentrated paste of the second juice of the prescription is concentrated to a specific gravity of 1.14-1.18, the concentration period is 4-6h, and the concentration temperature is ≤70℃.

[0210] The A group of material bags, the B group of material bags, the C group of material bags, the D group of material bags, and the E group of material bags are respectively put into the immersion tank 11, and the above-mentioned prescription extraction and paste collection procedures are respectively performed; the A group of second juice concentrated paste, the B group of second juice concentrated paste, the C group of second juice concentrated paste, the D group of second juice concentrated paste, and the E group of second juice concentrated paste are respectively prepared.

[0211] S43, mixing paste:

[0212] The second juice concentrated paste of the Group A formula, the second juice concentrated paste of the Group B formula, the second juice concentrated paste of the Group C formula, the second juice concentrated paste of the Group D formula, and the second juice concentrated paste of the Group E formula are put into the paste mixing barrel to mix the paste.

[0213] Low-speed mixing and preheating for 10 min, stirring speed is 40 r / min, preheating temperature is 55°C; turn off the preheating and carry out vacuum homogenization for 20 min, vacuum pressure is 41.3-61.3 kPa.

[0214] In order to shorten the production cycle, the Group A formula, the Group B formula, and the Group C formula are combined into three groups, and the Group D formula and the Group E formula are combined into two groups for pilot production.

[0215] The pilot production three includes:

[0216] S51, material pretreatment:

[0217] The materials are prepared according to 4000 servings / batch.

[0218] The broken "American ginseng, Dangshen", double weighing and rechecking are carried out and are packed separately for standby.

[0219] "Ophiopogon, Astragalus, Pueraria", double weighing and rechecking are carried out, and are packed together with the packed "American ginseng" into the Group A formula material bag for standby.

[0220] "Fu Ling, Shanyao, Shanzha", double weighing and rechecking are carried out, and are packed together with the packed "Dangshen" into the Group B formula material bag for standby.

[0221] "Huazhu Hong, Tao Ren, Astragalus, Shanzha", double weighing and rechecking are carried out, and are packed into the Group C formula material bag for standby.

[0222] "Shanzha, Tianma, Oyster, Shanyao", double weighing and rechecking are carried out, and are packed into the Group D formula material bag for standby.

[0223] "Yuzhu, Ophiopogon, Gancao, Pueraria", double weighing and rechecking are carried out, and are packed into the Group E formula material bag for standby.

[0224] S521, first juice extraction of the three groups and first juice concentrated paste of the three groups:

[0225] The Group A formula material bag, the Group B formula material bag, and the Group C formula material bag are put into the immersion liquid tank 11, six times the weight of drinking water is injected into the immersion liquid tank 11, and soaked for at least 12 h; the immersion liquid tank 11 is kept warm for 2 h and circulates, the temperature is ≤70°C.

[0226] The three groups of first juice extraction liquid in the immersion liquid tank 11 are transported and / or pumped to the extraction tank 13 through the filter 12.

[0227] The vacuum state of the extraction tank 13 is maintained, and the three groups of first juice extraction liquid in the extraction tank 13 is heated and concentrated to three groups of first juice concentrated paste with a specific gravity of 1.08-1.14, the concentration period is 10-12h, and the concentration temperature is ≤70℃.

[0228] The three groups of first juice concentrated paste in the extraction tank 13 is pumped into the concentration tank 14.

[0229] S522, second juice extraction of the three groups and second juice concentrated paste collection of the three groups:

[0230] The immersion liquid tank 11 is injected with six times the weight of drinking water, and soaked for at least 12h; the immersion liquid tank 11 is kept warm for 2h and circulated, and the warm temperature is ≤70℃.

[0231] The two groups of first juice extraction liquid in the immersion liquid tank 11 is transported and / or pumped into the extraction tank 13 through the filter 12.

[0232] The vacuum state of the extraction tank 13 is maintained, and the two groups of first juice extraction liquid in the extraction tank 13 is heated and concentrated to two groups of first juice concentrated paste with a specific gravity of 1.08-1.14, the concentration period is 10-12h, and the concentration temperature is ≤70℃.

[0233] S531, first juice extraction of the two groups and first juice concentrated paste collection of the five groups:

[0234] The immersion liquid tank 11 is injected with six times the weight of drinking water, and soaked for at least 12h; the immersion liquid tank 11 is kept warm for 2h and circulated, and the warm temperature is ≤70℃.

[0235] The two groups of first juice extraction liquid in the immersion liquid tank 11 is transported and / or pumped into the extraction tank 13 through the filter 12.

[0236] The vacuum state of the extraction tank 13 is maintained, and the two groups of first juice extraction liquid in the extraction tank 13 is heated and concentrated to two groups of first juice concentrated paste with a specific gravity of 1.08-1.14, the concentration period is 10-12h, and the concentration temperature is ≤70℃.

[0237] The two groups of first juice concentrated paste in the extraction tank 13 is pumped into the concentration tank 14 and mixed with the three groups of second juice concentrated paste.

[0238] The vacuum state of the concentration tank 14 is maintained, and the three groups of second juice concentrated paste and the two groups of first juice extraction liquid in the concentration tank 14 is heated and concentrated to five groups of first juice concentrated paste with a specific gravity of 1.14-1.18, the concentration period is 2-3h, and the concentration temperature is ≤70℃.

[0239] S532, the second juice extraction of the two groups and the second juice concentration of the five groups:

[0240] The infusion tank 11 is filled with four times the weight of drinking water and soaked for at least 12 hours; the infusion tank 11 is kept at a temperature of ≤70°C for 2 hours and circulated.

[0241] The second juice extraction liquid of the two groups in the infusion tank 11 is pumped through the filter 12 into the concentration tank 14 and mixed with the first juice concentrated paste of the five groups in the concentration tank 14.

[0242] The first juice concentrated paste of the five groups and the second juice extraction liquid of the two groups in the concentration tank 14 are heated and concentrated under vacuum in the concentration tank 14 to a specific gravity of 1.14-1.18, and the concentration cycle is 1-2 hours and the concentration temperature is ≤70°C.

[0243] In the first pilot production mode: the overall production cycle of 2000 servings per batch is 37-40 hours.

[0244] In the second pilot production mode: the overall production cycle of 8000 servings per batch is 113.5-114 hours.

[0245] In the third pilot production mode: the overall production cycle of 4000 servings per batch is 58-59 hours.

[0246] Table II is a comparison of the production cycle of the first pilot production, the second pilot production, and the third pilot production:

[0247]

[0248] The output efficiency in the second pilot production is greater than that in the third pilot production, and the output efficiency in the first pilot production is the lowest; the production cycle per serving in the second pilot production is shorter; the production cycle per serving in the third pilot production is close to that in the second pilot production, and there is no need to add the groups multiple times, making the operation more convenient.

[0249] In order to improve the production efficiency, the continuous production mode is adopted for the pilot production.

[0250] The fourth pilot production includes:

[0251] In the above steps S521, the first juice extraction of the three groups and the first juice concentrated paste of the three groups, and in the above steps S531, the first juice extraction of the two groups and the first juice concentrated paste of the five groups:

[0252] The concentration temperature of the first juice concentrated paste of the three groups and the first juice concentrated paste of the two groups is 55-60°C, and the temperature is controlled in stages: 58-60°C for the first 4 hours, 55-58°C for the middle 6 hours, and 52-55°C for the last 4 hours, and the final temperature is kept at 53±1°C.

[0253] The concentration periods of the first juice of the three groups of prescriptions and the first juice of the two groups of prescriptions are respectively extended, so that the second juice extraction of the three groups of prescriptions and the second juice extraction of the two groups of prescriptions are respectively carried out.

[0254] In the above step S522, the second juice extraction of the three groups of prescriptions and the second juice concentration of the three groups of prescriptions:

[0255] The concentration temperature of the second juice concentrated paste of the three groups of prescriptions and the first juice concentrated paste of the five groups of prescriptions is 50-55℃, and a staged temperature control is adopted: 54-55℃ for the first 6 hours, 52-53℃ for the middle 6 hours, 50-51℃ for the last 2 hours, and the end temperature is kept at 50-51℃.

[0256] The concentration period of the second juice concentration of the three groups of prescriptions is extended, so that the first juice extraction of the two groups of prescriptions is carried out, and the second juice extraction liquid of the three groups of prescriptions is mixed with the first juice concentrated liquid of the three groups of prescriptions, and then heated and concentrated at the same time.

[0257] In the above step S531, the first juice extraction of the two groups of prescriptions and the first juice concentration of the five groups of prescriptions, and in the above step S532, the second juice extraction of the two groups of prescriptions and the second juice concentration of the five groups of prescriptions:

[0258] The concentration temperature of the first juice concentrated paste of the five groups of prescriptions and the second juice concentrated paste of the five groups of prescriptions is ≤70℃, and when the specific gravity of the second juice concentrated paste of the five groups of prescriptions reaches 1.16, the heating is turned off and the concentration is completed by using the residual heat.

[0259] In the mode of the fourth pilot production, the concentration temperature is lowered, and the heating energy consumption and the refrigerant energy consumption are lower.

[0260] The fourth pilot production further includes:

[0261] S6, collection and storage:

[0262] The output second juice concentrated paste of the five groups of prescriptions is collected and concentrated in a clean stainless steel barrel, sealed, and the material state card is pasted on the barrel cover and barrel body of the stainless steel barrel, and stored in the cold storage for standby.

[0263] The output wet paste is 200-240kg, and the dry paste is 76-84kg.

[0264] S7, drying:

[0265] The vacuum belt dryer is set to have a partition temperature of 60℃-65℃-55℃, and the wet paste with impurities removed by passing through a 100-mesh sieve is thrown into the vacuum belt dryer through the feeding port for drying.

[0266] During the drying, the pump port pressure of the vacuum pump is ≤0.095 MPa, the pipeline pressure rises ≤0.01 MPa within 5 minutes in the vacuum state, the pressure in the vacuum belt dryer is 0.08-0.09 MPa, the conveying speed is 0.8-1.5 m / h, the paste on the conveying belt is uniformly laid with a thickness of 3-5 mm, and the drying period is 5-6 h.

[0267] After drying, the moisture content of the material is ≤6%, the moisture content difference of the material is ≤1.5%, and the bulk density of the material is 0.3-0.6 g / mL.

[0268] S8, crushing:

[0269] The dried material and dry paste are pre-crushed through a 20-mesh sieve, fed into an air jet mill through a feed port, and crushed.

[0270] During the crushing, the wheel rotation speed is 4000-6000 rpm, the feeding speed is 10-30 kg / h, the gas-solid ratio is 2:1-5:1, the pulse backflush interval time is 30 s, the gas source pressure is 0.7-1.0 MPa, and the gas source dew point is ≤-40℃.

[0271] S9, granulation and sizing:

[0272] The inlet air temperature of the fluidized bed granulator is set to 90℃±5℃, steam preheating is performed, and the preheating temperature is 80℃.

[0273] The crushed material 52.2㎏, tailings 15㎏, and dextrin 22.8㎏ are fed into the fluidized bed granulator, the inlet air port is adjusted, the spray gun pressure is 0.2-0.3 MPa, the peristaltic pump speed is 80 rpm, and after 5 minutes of air supply mixing, the infusion paste is started, the peristaltic pump speed is slowly adjusted according to the infusion paste, and the material in the fluidized bed granulator is observed to be in a boiling state.

[0274] After the infusion paste is sprayed, drying is continued for 40 minutes, the first output of the granules is 116 kg, of which the dextrin accounts for 23.8%, 15㎏ of tailings is taken out for standby and will be fed into the next granulation, of which the dextrin content is 4.9㎏, and 22.8㎏ of dextrin is added, and the second output of the granules is 232 kg.

[0275] The output granules are sized through a 12-mesh sieve.

[0276] S10, total mixing and packaging:

[0277] After the sizing is completed, the granules are fed into the mixer, mixed for 10 minutes, and then collected.

[0278] The composite film is clamped on both sides of the packaging material shaft of the packaging machine, and the production date head with the same size is replaced; before starting, check whether there is any abnormal phenomenon, adjust the small bag until it is straight, wrinkle-free, and tightly sealed; set the printing temperature to 160-210℃, the horizontal sealing temperature to 160-260℃, and the vertical sealing temperature to 160-260℃, and preheat; start the machine to pack 6g per bag, add the particles into the hopper, adjust the loading amount, weigh 4 bags each time, and weigh at least once every 15 minutes after the loading amount is qualified, and check the appearance at any time and record.

[0279] To sum up, only the preferred embodiments of the present application are described, and the scope of the present application is not limited. Based on the above description, relevant personnel can make various changes and modifications without deviating from the technical idea of the present application. The technical scope of the present application is not limited to the content of the specification. Any equivalent changes and modifications of shape, structure, features and spirit within the scope of the present application shall be included in the scope of the claims of the present application.

Claims

1. A special dietary protein peptide particle based on multi-component allocation ratio, characterized in that: The formula of the preparation raw material of the protein peptide particle is: 10-20g of polygonatum, 8-15g of hoelen, 3-8g of licorice, 10-18g of hawthorn, 3-8g of American ginseng 10-18g of radix puerariae, 3-8g of fructus aurantii, 6-15g of ophiopogon, 12-20g of Chinese yam, 8-18g of dangshen 12-18g of radix paeoniae alba, 12-18g of yuzhu, 8-15g of gastrodia, 8-15g of peach kernel, 12-20g of concha mallei.

2. The special dietary protein peptide particle based on multi-component allocation ratio according to claim 1, characterized in that: The formula of the preparation raw material of the above fifteen ingredients is: Group A: formula ratio: Lord: American ginseng 3-8g; vassal: ophiopogon 2-5g; assistant: radix puerariae 4-8g; make: radix puerariae 2-4g; Group B: formula ratio: Lord: hoelen 8-15g; vassal: Chinese yam 10-16g; assistant: hawthorn 4-6g; make: dangshen 8-18g; Group C: formula ratio: Lord: fructus aurantii 3-8g; vassal: peach kernel 8-15g; assistant: radix puerariae 8-10g; Make: hawthorn 6-12g; Group D: formula ratio: Lord: yuzhu 12-18g; vassal: gastrodia 8-15g; assistant: concha mallei 12-20g; make: Chinese yam 2-4g; Group E: formula ratio: Lord: polygonatum 10-20g; vassal: ophiopogon 4-10g; assistant: licorice 3-8g; make: radix puerariae 8-14g.

3. The concentrated production process of the special dietary protein peptide particle based on multi-component allocation ratio, the protein peptide particle based on multi-component allocation ratio according to claim 1, characterized in that: S11, material pretreatment: "polygonatum, hoelen, licorice, hawthorn, radix puerariae, fructus aurantii, ophiopogon, Chinese yam, radix puerariae, yuzhu, gastrodia, peach kernel, concha mallei", and "American ginseng, dangshen" after breaking the wall, are weighed and bagged for standby respectively; S12, extraction: Soak the bagged material in the soaking bottle and inject six times the weight of drinking water for soaking; S13, concentrated paste: Start the vacuum concentrator, and pump the extraction liquid in the soaking bottle into the vacuum concentrator, and start the heating disc to concentrate the extraction liquid.

4. The concentrated production process of the special dietary protein peptide particle based on multi-component allocation ratio according to claim 3, characterized in that: S21, material pretreatment: "polygonatum, hoelen, licorice, hawthorn, radix puerariae, fructus aurantii, ophiopogon, Chinese yam, radix puerariae, yuzhu, gastrodia, peach kernel, concha mallei", and "American ginseng, dangshen" after breaking the wall, are weighed and bagged for standby respectively; S22, first juice extraction: Soak the bagged material in the soaking bottle and inject six times the weight of drinking water for soaking, and then perform water bath heating; S23, first juice concentrated paste: Start the vacuum concentrator, and pump the first juice extraction liquid in the soaking bottle into the vacuum concentrator, and start the heating disc to concentrate the first juice extraction liquid into the first juice concentrated paste; S24, second juice extraction: Soak the soaking bottle with four times the weight of drinking water, and then perform water bath heating; S25, second juice concentrated paste: Start the vacuum concentrator, the second juice extraction liquid in the immersion bottle is extracted into the vacuum concentrator and mixed with the first juice concentrate, and the heating disc is opened to concentrate the first juice concentrate and the first juice extraction liquid into the second juice concentrate.

5. The production process of special dietary protein peptide particles based on multi-component allocation ratio according to claim 2, wherein: The concentration process in the production process is pilot-produced by a cream collection device, and the cream collection device comprises: The immersion tank (11), filter (12), extraction tank (13), concentration tank (14), buffer tank (15), and condenser (21) are arranged on the pry frame, and the recovery tank (40) is arranged on one side of the pry frame; A sight glass feeding port is arranged at the upper end of the immersion tank (11), a central immersion liquid discharge port is arranged at the lower end of the immersion tank (11), a circulating pump (30) is arranged in communication with the pipeline of the immersion liquid discharge port, the outlet of the circulating pump (30) is connected in communication with the upper end of the immersion tank (11) and the upper end of the filter (12) through a three-way pipe, a central filter liquid discharge port is arranged at the lower end of the filter (12), the pipeline of the filter liquid discharge port is connected in communication with the extraction tank (13), a central extraction liquid discharge port is arranged at the lower end of the extraction tank (13), the pipeline of the extraction liquid discharge port is connected in communication with the concentration tank (14), a central concentration cream discharge port is arranged at the lower end of the concentration tank (14), a central exhaust port is arranged at the upper end of the extraction tank (13) and the concentration tank (14), the exhaust port is connected in communication with the pipe inlet of the condenser (21), a recovery tank (22) is arranged in communication with the pipe outlet of the condenser (21), a sight pipe (23) is arranged in communication with the recovery tank (22), the lower end of the sight pipe (23) is connected in communication with the upper end of the extraction tank (13), the upper end of the concentration tank (14), and the upper end of the buffer tank (15) through a U-shaped pipe, the upper end of the buffer tank (15) is connected in communication with a vacuum unit, a central recovery liquid discharge port is arranged at the lower end of the buffer tank (15), the pipeline of the recovery liquid discharge port is connected in communication with the upper end of the recovery tank (40), and a tank pump is arranged in the recovery tank (40); The immersion tank (11), extraction tank (13), and concentration tank (14) are provided with heating jackets; The buffer tank (15) and the recovery tank (22) are provided with cooling jackets, and the shell side of the cooling jacket and the condenser (21) is connected in communication with the circulating pipeline of the refrigerant.

6. The production process of special dietary protein peptide particles based on multi-component allocation ratio according to claim 5, wherein: The production process comprises: S31, material pretreatment: Prepare materials according to 2000 servings / batch; "Anemarrhena, Poria cocos, licorice, hawthorn, radix puerariae, citrus red, ophiopogon, Chinese yam, astragalus, dogwood, Gastrodia, peach kernel, oyster", and "western ginseng, radix codonopsis" after breaking, double weighing and rechecking, and bagging for standby; S321, first juice extraction: Pour six times the weight of drinking water into the bagged material in the immersion tank (11) for immersion; Keep warm through the jacket, start the circulating pump (30), and ensure that the liquid level in the immersion tank (11) is higher than the material bag; S322、first juice concentrate: Through the circulating pump (30) and / or vacuum unit, the first juice extract in the immersion tank (11) is sent to the extraction tank (13) through the filter (12); Through the heating of the spacer, the first juice extract in the extraction tank (13) is concentrated into the first juice concentrate under vacuum; The water vaporization is condensed in sequence from the exhaust port of the extraction tank (13) through the tube of the condenser (21), the recovery tank (22), the sight tube (23), and the buffer tank (15), until the condensed water is collected in the buffer tank (15) under vacuum; Through the vacuum unit, the first juice concentrate in the extraction tank (13) is extracted into the concentration tank (14); S331、second juice extraction: The immersion tank (11) is filled with four times the weight of drinking water for soaking; Through the spacer, the immersion tank (11) is kept warm, the circulating pump (30) is started, and the liquid level in the immersion tank (11) is kept higher than the material bag; S332、second juice concentrate: Through the circulating pump (30) and vacuum unit, the second juice extract in the immersion tank (11) is pumped into the concentration tank (14) through the filter (12) and mixed with the first juice concentrate in the concentration tank (14); Through the heating of the spacer, the first juice concentrate and the second juice extract in the concentration tank (14) are concentrated into the second juice concentrate under vacuum; The water vaporization is condensed in sequence from the exhaust port of the concentration tank (14) through the tube of the condenser (21), the recovery tank (22), the sight tube (23), and the buffer tank (15), until the condensed water is collected in the buffer tank (15) under vacuum.

7. The production process of special dietary protein peptide particles based on multiple component allocation ratios according to claim 5, characterized in that: The pipeline of the filter (12) filtrate discharge port is connected with a three-way pipe fitting, which is connected with the extraction tank (13) and the concentration tank (14) respectively.

8. The production process of special dietary protein peptide particles based on multiple component allocation ratios according to claim 7, characterized in that: The production process comprises: S41, material pretreatment: Prepare materials for 8000 servings per batch; After breaking the wall, "American ginseng", "magnolia officinalis, astragalus, pueraria", are double-weighed and rechecked respectively, and are loaded into A group formula material bag for standby; After breaking the wall, "American ginseng", "magnolia officinalis, astragalus, pueraria", are double-weighed and rechecked respectively, and are loaded into A group formula material bag for standby; "Chinese orange red, peach kernel, astragalus, hawthorn", are double-weighed and rechecked, and are loaded into C group formula material bag for standby; "Chinese orange red, peach kernel, astragalus, hawthorn", are double-weighed and rechecked, and are loaded into C group formula material bag for standby; "Chinese orange red, peach kernel, astragalus, hawthorn", are double-weighed and rechecked, and are loaded into C group formula material bag for standby; S42, formula extraction and concentrate: The immersion tank (11) is filled with six times the weight of drinking water for soaking, and the circulating pump (30) is started under heat preservation to circulate the soaking liquid; The first juice extraction solution in the immersion tank (11) is transported and / or pumped to the extraction tank (13) through the filter (12), and the first juice extraction solution in the extraction tank (13) under vacuum is heated and concentrated into the first juice concentrated paste of the formula, and the first juice concentrated paste in the extraction tank (13) is pumped into the concentration tank (14); The immersion tank (11) is injected with four times the weight of drinking water for soaking, and the circulating pump (30) is started under heat preservation to circulate the soaking liquid, and the second juice extraction solution in the immersion tank (11) is pumped to the concentration tank (14) through the filter (12), and mixed with the first juice concentrated paste in the concentration tank (14), and the first juice concentrated paste and the second juice extraction solution in the concentration tank (14) under vacuum are heated and concentrated into the second juice concentrated paste of the formula; Any one of the A formula material bag, the B formula material bag, the C formula material bag, the D formula material bag and the E formula material bag is respectively put into the immersion tank (11), and the A formula second juice concentrated paste, the B formula second juice concentrated paste, the C formula second juice concentrated paste, the D formula second juice concentrated paste and the E formula second juice concentrated paste are respectively prepared; S43, paste mixing: The A formula second juice concentrated paste, the B formula second juice concentrated paste, the C formula second juice concentrated paste, the D formula second juice concentrated paste and the E formula second juice concentrated paste are mixed.

9. The production process of special dietary protein peptide particles based on multi-component allocation ratio according to claim 7, characterized in that: S51, material pretreatment: Prepare materials according to 4000 servings / batch; The broken "American ginseng", and "magnolia, astragalus, pueraria", are respectively double-weighed and rechecked, and are loaded into the A formula material bag for standby; The broken "dangshen", and "tuckahoe, yam, hawthorn", are respectively double-weighed and rechecked, and are loaded into the B formula material bag for standby; "orange peel, peach kernel, astragalus, hawthorn", are double-weighed and rechecked, and are loaded into the C formula material bag for standby; "cornus officinalis, gastrodia, oyster, yam", are double-weighed and rechecked, and are loaded into the D formula material bag for standby; "jade bamboo, magnolia, licorice, pueraria", are double-weighed and rechecked, and are loaded into the E formula material bag for standby; S521, first juice extraction of three formulas and first juice concentrated paste collection of three formulas: The A formula material bag, the B formula material bag and the C formula material bag are put into the immersion tank (11), and six times the weight of drinking water is injected into the immersion tank (11) for soaking, and the circulating pump (30) is started under heat preservation to circulate the soaking liquid; The three formula first juice extraction solution in the immersion tank (11) is transported and / or pumped to the extraction tank (13) through the filter (12); The three formula first juice extraction solution in the extraction tank (13) under vacuum is heated and concentrated into the three formula first juice concentrated paste; The three formula first juice concentrated paste in the extraction tank (13) is pumped into the concentration tank (14); S522, second juice extraction of three formulas and second juice concentrated paste collection of three formulas: The immersion tank (11) is injected with four times the weight of drinking water for soaking, and the circulating pump (30) is started under heat preservation to circulate the soaking liquid; The three groups of second juice extraction liquid in the immersion tank (11) is pumped to the concentration tank (14) through the filter (12) and mixed with the three groups of first juice concentrated paste in the concentration tank (14); The three groups of first juice concentrated paste and the three groups of second juice extraction liquid in the concentration tank (14) under vacuum state are heated and concentrated into three groups of second juice concentrated paste; S531, the first juice extraction of two groups and the first juice concentration of five groups: The D group material bag and the E group material bag are put into the immersion tank (11), and six times of weight of drinking water is injected into the immersion tank (11) for immersion, and the circulating pump (30) is started under the condition of heat preservation to circulate the immersion liquid; The two groups of first juice extraction liquid in the immersion tank (11) is transported and / or pumped into the extraction tank (13) through the filter (12); The two groups of first juice extraction liquid in the extraction tank (13) under vacuum state is heated and concentrated into two groups of first juice concentrated paste; The two groups of first juice concentrated paste in the extraction tank (13) is pumped into the concentration tank (14) and mixed with the three groups of second juice concentrated paste; The three groups of second juice concentrated paste and the two groups of first juice extraction liquid in the concentration tank (14) under vacuum state are heated and concentrated into five groups of first juice concentrated paste; S532, the second juice extraction of two groups and the second juice concentration of five groups: Four times of weight of drinking water is injected into the immersion tank (11) for immersion, and the circulating pump (30) is started under the condition of heat preservation to circulate the immersion liquid; The two groups of second juice extraction liquid in the immersion tank (11) is pumped to the concentration tank (14) through the filter (12) and mixed with the five groups of first juice concentrated paste in the concentration tank (14); The five groups of first juice concentrated paste and the two groups of second juice extraction liquid in the concentration tank (14) under vacuum state are heated and concentrated into five groups of second juice concentrated paste.

10. The production process of special dietary protein peptide particles based on multiple distribution ratios according to claim 9, characterized in that: In the above steps S521, the first juice extraction of three groups and the first juice concentration of three groups: The concentration temperature of the first juice concentrated paste of three groups is reduced, and the temperature is controlled in stages, so that the concentration period of the first juice concentrated paste of three groups is prolonged, so that the second juice extraction of three groups is carried out; In the above steps S522, the second juice extraction of three groups and the second juice concentration of three groups: The concentration temperature of the second juice concentrated paste of three groups is reduced, and the temperature is controlled in stages, so that the concentration period of the second juice concentrated paste of three groups is prolonged, so that the first juice extraction of two groups is carried out, and the mixed second juice extraction liquid of three groups and the first juice concentrated liquid of three groups are heated and concentrated at the same time; In the above steps S531, the first juice extraction of two groups and the first juice concentration of five groups: The concentration temperature of the first juice concentrated paste of two groups is reduced, and the temperature is controlled in stages, so that the concentration period of the first juice concentrated paste of two groups is prolonged, so that the second juice extraction of two groups is carried out respectively; The concentration temperature of the first juice concentrated paste of five groups is maintained, and the mixed second juice concentrated liquid of three groups and the first juice extraction liquid of two groups are heated and concentrated at the same time; In the above steps S532, the second juice extraction of two groups and the second juice concentration of five groups: The five groups of second juice concentrate paste are kept at the concentration temperature, and the mixed five groups of first juice concentrate and two groups of second juice extract are simultaneously heated and concentrated, and the concentration is completed by using the residual heat.