Solid wound bleeding stopping spider web band-aid for treating wound bleeding and manufacturing method of solid wound bleeding stopping spider web band-aid

Abstract

The invention provides a solid wound hemostasis spider web band-aid for treating wound bleeding and a manufacturing method of the solid wound hemostasis spider web band-aid, and belongs to the technical field of band-aids. The band-aid comprises a medicine core covering film, a water-absorbable combined medicine core, a medical pressure-sensitive adhesive and an elastic cloth backing, the water-absorbable combined medicine core is arranged above the medicine core covering film, and the medical pressure-sensitive adhesive is arranged on the elastic cloth backing; the medical pressure-sensitive adhesive is arranged above the water-absorbable combined medicine core in a covering mode, and the elastic cloth backing is arranged above the medical pressure-sensitive adhesive. According to the invention, araneus cobweb and gold sore hemostatic powder is used, and the principle of araneus cobweb hemostasis in the aspect of current western medicine is perfectly applied: the araneus cobweb has high-efficiency water absorption, and the araneus cobweb has the functions of stopping bleeding and stopping gold sore bleeding due to the intelligent crystallization of ancient predecessor, the main liking function of araneus cobweb and the current western medicine; a substance named as' serine 'in araneus cobweb has a hemostasis effect and the araneus cobweb has high-efficiency water absorption; the hemostasis and tissue regeneration promoting prescription of the traditional Chinese medicine golden-skin-wound hemostasis powder is also found, effective hemostasis components or medicinal materials of the golden-skin-wound hemostasis powder and the golden-skin-wound hemostasis powder are extracted, Chinese and western are combined, innovation is combined, and the uniqueness of the product is embodied.

Description

Technical Field

[0001] This invention relates to the field of adhesive bandage technology, and in particular to a solid spider web adhesive bandage for treating bleeding wounds and its manufacturing method. Background Technology

[0002] In traditional Chinese medicine, "Jin Chuang" refers to wounds caused by metal instruments such as knives and arrows; in Western medicine, it is called tetanus. It is primarily caused by skin or muscle damage from puncture wounds caused by knives, scissors, etc., leading to infection with tetanus bacteria and resulting in seizures.

[0003] Firstly, adhesive bandages effectively cover wounds, preventing external dust, bacteria, and other contaminants from entering and reducing the risk of infection. They contain absorbent materials that can absorb fluid from the wound, keeping it dry and providing a suitable environment to promote healing. Furthermore, in cases of minor trauma, adhesive bandages can apply a certain amount of pressure to help stop bleeding and reduce the amount of bleeding. Most adhesive bandages contain some analgesic ingredients, which can reduce pain and discomfort around the wound.

[0004] The non-neonatal high-risk population for tetanus is primarily composed of individuals at high risk of potential trauma. Although passive tetanus immunization after trauma can effectively reduce morbidity, its short duration of protection and inability to provide lasting protection to high-risk groups, along with the risk of sensitization, have led the World Health Organization (WHO) and countries like the United States to recommend tetanus vaccination strategies for high-risk populations. As tetanus is a vaccine-preventable disease, how to effectively implement pre-exposure prophylaxis for non-neonatal high-risk populations in my country to reduce the disease burden is a crucial public health issue requiring attention.

[0005] Although the incidence of traumatic injuries is not high in today's society, its mortality rate is relatively high. The danger lies in the toxins it secretes, which are extremely potent. Traumatic injuries are risky if there are any abnormal wounds, deep wounds, heavily contaminated wounds, or cuts from metal objects. Symptoms of traumatic injuries include cyanosis of the face and lips, a bitter smile, paroxysmal muscle spasms, opisthotonus, trismus, and difficulty breathing. In severe cases, some patients may die from suffocation.

[0006] Studies have shown that tetanus toxin is primarily released by Clostridium tetani, circulating through the peripheral motor nervous system, blood, and lymphatic system before reaching the central nervous system. There, it binds to inhibitory neurons in the spinal cord, inhibiting the release of acetylcholine, increasing body tension, and ultimately causing spasms. Before the onset of the disease, patients often experience headaches, dizziness, general fatigue and weakness, and muscle tightness. Furthermore, the disease can lead to epilepsy, heart failure, and lung problems, seriously endangering life.

[0007] In clinical practice, tetanus is classified into four grades using the Ablett classification system. A(1) Grade I mild tetanus: Patients present with general spasms, mild to moderate trismus, and usually do not experience convulsions or respiratory distress. (2) Grade II moderate tetanus: Patients present with significant spasms, moderate trismus, and a high respiratory rate, exceeding 30 breaths per minute (normal is 12-20 breaths per minute), with dyspnea and dysphagia, but without convulsions. (3) Grade III severe tetanus: Patients present with severe trismus, generalized spasms, extremely difficult breathing, even suffocation, and persistent reflexive convulsions. (4) Grade IV very severe tetanus: Patients have severe cardiovascular manifestations, such as hypertension, hypotension, tachycardia, or bradycardia. Grades II and IV are both severe tetanus cases, which are very difficult to treat in the ICU and have a very high mortality rate.

[0008] Wounds can occur at any age, but are more common in the elderly than in young people. The incidence rate is higher in developing countries, sometimes hundreds or even thousands of times higher than in developed countries. While wounds are not a seasonal disease, the incidence rate is higher in summer than in winter. In summer, we often wear short sleeves and light clothing, leaving much of our skin exposed. Abrasions, scratches, and falls at this time can directly damage our skin. Furthermore, the high summer temperatures increase bacterial activity, leading to a higher infection rate.

[0009] Its sequelae mainly include paroxysmal spasms, nerve excitation, and lung diseases.

[0010] ① Paroxysmal spasm: characterized by paroxysmal spasms in local muscles;

[0011] ② Nerve excitation: A large amount of toxins stimulates the central nervous system, leading to increased nerve excitability, manifested as increased heart rate, excessive sweating, etc.

[0012] ③ Lung diseases: These can damage lung tissue, increasing the risk of developing lung diseases such as pneumonia and emphysema. In addition, some patients may experience other sequelae such as respiratory failure and sepsis.

[0013] Western medicine treatment methods:

[0014] ① For mild cases, a band-aid can be applied directly;

[0015] ② For wounds caused by metal instruments on the limbs, first perform debridement to remove inactive and necrotic tissue, remove foreign objects, and rinse thoroughly with hydrogen peroxide, iodine solution, and saline solution. Investigate for damage to tendons, muscles, blood vessels, and nerves. For smaller vascular and nerve injuries, ligation or suturing may be considered.

[0016] ③ For larger blood vessels or important nerve injuries, repair is necessary, such as vascular sutures or microscopic repair. If the defect is extensive, artificial blood vessel replacement or transplantation with a pedicled vessel can be considered. For severe muscle and fascia injuries, partial resection can be performed. If the injury is minor, it can be directly sutured.

[0017] Traditional Chinese Medicine treatment methods:

[0018] ① Ancestral Knife Wound Scar-Free Powder: Ingredients: 9 grams each of safflower, frankincense, myrrh, and raw gypsum powder; 6 grams each of litharge, borneol, angelica dahurica, and talc; 3 grams of peppermint; and 0.3 grams of musk. Usage: For cuts and bleeding wounds caused by knives, axes, etc., sprinkle this powder on the wound and bandage it. No need to change the dressing; it will heal in one treatment and leave no scar (but the wound should not be soaked in water).

[0019] ② For example, Shengjin Knife Powder: 45g of dried alum, 45g of alum, and 210g of rosin. Usage: Clean the wound with saline or iodine, or absorb the moisture around the wound with an alcohol swab. Quickly sprinkle the powder on the wound and bandage with gauze. Change the dressing every three days; it usually heals in 5-7 days. Note: Avoid getting the wound wet from the time it is bandaged until the dressing is changed.

[0020] ③ A medicinal ointment made from medical red lead powder and ginger can effectively reduce swelling, promote tissue regeneration, and improve blood circulation. Meanwhile, the integration of traditional Chinese and Western medicine is currently widely used and has achieved excellent results, playing a significant role in promoting wound healing and improving patients' quality of life.

[0021] Therefore, there is a need to design a solid wound-healing bandage with a spider web-like structure that can quickly heal wounds, and its manufacturing method. Summary of the Invention

[0022] The purpose of this invention is to provide a solid spider web-shaped bandage for treating bleeding wounds and its manufacturing method, thereby solving the technical problem that there is currently no bandage specifically for bleeding wounds and that traditional bandages are ineffective.

[0023] To achieve the above objectives, the technical solution adopted by the present invention is as follows:

[0024] The Spider Web Solid Bandage for Treating Bleeding Wounds comprises a medicated core covering film, an absorbent medicated core, a medical pressure-sensitive adhesive, and an elastic backing. The absorbent medicated core is positioned above the medicated core covering film, the medical pressure-sensitive adhesive is positioned above the absorbent medicated core, and the elastic backing is positioned above the medical pressure-sensitive adhesive.

[0025] Furthermore, the absorbent composite core consists of a spider web and a wound-hemostatic powder. The wound-hemostatic powder is placed on the spider web, which dries the wound, stops bleeding, and absorbs water, acting as an absorbent pad to absorb blood seeping from the wound. The wound-hemostatic powder stops bleeding, reduces inflammation, promotes tissue regeneration, and accelerates wound healing.

[0026] Furthermore, the medication core is covered with a polyethylene film to prevent it from adhering to the wound.

[0027] Furthermore, the absorbent composite core is composed of biomimetic microfibers and Jin Chuang Zhi Xue San (a traditional Chinese medicine for treating hemorrhage), with Jin Chuang Zhi Xue San sprayed onto the biomimetic microfibers.

[0028] The method for making a solid spider web bandage for treating bleeding wounds involves collecting spider webs as an absorbent pad, preparing a hemostatic powder for treating wounds, spraying the hemostatic powder onto the absorbent pad to form a medicated core, placing the medicated core on a medicated core covering film, placing a medical pressure-sensitive adhesive and an elastic fabric backing on the medicated core at the same time, setting pressure to press together, then punching the film, packaging and sterilizing the box to complete the preparation.

[0029] Spider web, also known as spider silk (from the *Compendium of Materia Medica*), is derived from the web of the giant orb-weaver spider (L. Koch), an animal belonging to the genus *Araneaventricosa* in the family Araneidae. The original animal is a spider. It is slightly cold in nature and toxic. Its main uses are to stop bleeding and eliminate warts. It is primarily used to treat hematemesis, bleeding from wounds, warts, hematomas, and hemorrhoids. For example, *Sheng Hui Fang* states: "It treats sores and stops bleeding from wounds. Stir-fry until yellow, grind into powder, and take with wine to treat hematemesis." *Xin Xiu Ben Cao* states: "It can eliminate warts in seven days, with proven efficacy." *Ben Cao Meng Quan* states: "It can cause warts to rot and disappear, and treat hemorrhoids and fistulas to fall off." Spider webs should be collected and used immediately. Pharmacological studies have shown that it can shorten the clotting time in rabbits. For internal use: grind into powder, apply as needed. For external use: wrap or grind into powder and sprinkle.

[0030] Invention: (Li Shizhen said) According to Hou Yanshang's "Retreating to the Studio of Leisurely Study," for anyone who suddenly vomits blood, take a large spider web, roll it into a small ball, and swallow it with rice water; one dose will stop the bleeding immediately. This is a prescription passed down by Sun Shaoxian. Also, "Miscellaneous Records of Youyang" states: Pei Min, while traveling in the mountains, saw a spider spinning a web as large as a bolt of cloth. He drew his bow and shot it, cutting several feet of silk and collecting it. His subordinates with wounds were given a square piece cut and applied; the bleeding stopped immediately. Thus, spider webs are indeed used to stop bleeding. (From "Complete Medical Works of Li Shizhen") Selected Prescriptions: ① For treating anal hemorrhoids, the spider web will become entangled and fall off. (From "Compendium of Materia Medica," quoting "Simple Prescriptions")

[0031] ② For treating hematomas, take a large spider web from the mountains, and use fresh silk threads to bind it to the base of the hematoma, gradually tightening it until it withers and falls off, without damaging the skin or flesh. The method for treating external hemorrhoids is the same. (From *Yilin Zuanyao*)

[0032] Spiders, also known as *Ara-neaventricosa* (L. Koch), are a species of spider belonging to the genus *Ara-neaventricosa* in the family Araneidae. Adult females are approximately 30 mm long, while males are approximately 15 mm. The cephalothorax is shorter than the abdomen and is dark brown. The cephalothorax is pear-shaped, flat, and covered with small white hairs. It has eight eyes clustered in three ocellariiformis, with four eyes on the central ocellariiformis at the anterior margin and two eyes on each lateral ocellariiformis. The chelicerae are strong and have seven small teeth. It has strong, spiny legs with dark rings. The abdomen is nearly round and large, with raised shoulders and a clear leaf-like band along the center of the back, extending along the tongue-like body, which is spindle-shaped. There are eight pairs of small round spots along the midline. The abdomen has one pair of white spots. The genitals are black, tongue-like, and spindle-shaped. It mainly inhabits eaves, corners, and trees, weaving wheel-like webs. It is active at dusk and night, feeding on insects. It is found throughout my country and is the most common spider, with *Aranea ventricosa* found in most parts of the country. Its overall shape is round or oval; the head and thorax are reddish-brown with black edges. The abdomen is yellowish-brown with distinct black leaf-like markings and two pairs of black muscle spots. There is a yellow or red spot in the center of the anterior abdomen, and the underside is grayish-yellow. The spinnerets are dark brown. The legs are yellowish-brown or dark brown with reddish-brown or dark brown rings, and there are six pairs of appendages, often incomplete. It is light and brittle. It has a faint odor and a slightly bitter and salty taste. When processing, use the original medicinal material, remove impurities, store in a dry container in a cool, dry place, protected from moisture and insects. It is bitter and cold in nature. It is toxic. It enters the liver meridian.

[0033] Spider web absorbency:

[0034] Spider silk is a protein fiber secreted by spiders through glands under mild conditions. Spider silk is mainly composed of one or more protein strands, called spider silk protein, and has a large molecular weight. The composition of spider silk protein varies depending on the type of spider silk. Spider silk has a layer of preservative on its surface; the ancient Greeks used spider silk to stop bleeding and promote wound healing. Compared to other natural materials, spider silk has excellent mechanical properties and good biocompatibility, making it highly favored by researchers.

[0035] The principle behind spider silk's water-collecting ability is that spider silk has a certain degree of hydrophilicity. In humid weather, it can absorb moisture from the air, forming water droplets that slide onto the spider web. The surface of spider silk has many tiny capillaries that allow water molecules to adhere to the surface. Along the "trunk" formed by two fibers, there are many spindle-shaped micro-protrusions made of nanofibers. When moisture in the air condenses on the surface of the spider silk, it gathers at these micro-protrusions to form large water droplets.

[0036] Inspired by natural spider webs, researchers have developed biomimetic microfibers that can extract fresh water from the atmosphere. These fibers have hollow channels that can efficiently collect water. The volume of the suspended droplets of the biomimetic ultrafine fibers is 1663 times that of the spindle volume, far higher than the current world record for water absorption capacity (571 times). The reason for this high water absorption is the construction of a hollow structure in the fiber. When small water droplets condense on the spider web, they move towards the spindle joint under the action of buoyancy to achieve water collection.

[0037] Given the efficient water collection ability of spider webs, spider webs are made into a medicated core absorbent pad to absorb the blood oozing from wounds, while stopping bleeding from incised wounds, stopping bleeding and removing warts, and promoting wound healing.

[0038] Jin Chuang Zhi Xue San, Function: Relieve pain in dry sores, promote granulation and flesh growth.

[0039] Composition: Seven liang of weathered lime (finely ground, soaked in urine for three days and three nights, filtered out and dried in the sun, made into powder), three liang of dragon's blood (removing the fine powder, stir-fried until purple), ten eggs (taking the egg whites, mixing with the weathered lime, making into three pills, burning in charcoal fire until red, taking out and exposing to fire poison on the ground for one night).

[0040] Usage: Grind the above ingredients into fine powder and sprinkle it on the sores gradually.

[0041] Treatment: ① Lime is made by heating and calcining limestone. It is pungent, warm in nature and poisonous. It is mainly used for drying dampness, killing insects, stopping bleeding, relieving pain, and corroding evil flesh. It can treat scabies, damp sores, traumatic bleeding, scalds and burns, hemorrhoids, rectal prolapse, and verrucae. Taken orally, it can treat diarrhea, dysentery, metrorrhagia and leukorrhagia.

[0042] ② An egg can be divided into several parts such as eggshell, egg white, egg yolk, and phoenix garment (inner membrane). For the ingredients, please refer to each item. It nourishes yin and moistens dryness, nourishes blood and prevents miscarriage. It can treat restlessness and fever, dry cough with hoarseness, red eyes and sore throat, fetal movement restlessness, thirst after childbirth, dysentery, and burns.

[0043] ③ Dragon's blood, also known as qi lin jie, hai la, qi lin xue, mu xue jie, is an over-the-counter drug made from the fruits and trunk resins of the palm plant Dracaena cochinchinensis. It has the effects of promoting blood circulation to remove blood stasis, relieving pain, stopping bleeding and promoting granulation. It is mainly used for treating traumatic injuries, stasis and pain in the chest and abdomen, traumatic bleeding, and non-healing sores and ulcers.

[0044] Advantages of Jin Chuang Zhi Xue San:

[0045] ① It has a strong hemostatic effect and can quickly stop bleeding and make the wound scab.

[0046] ② The scab combines very tightly and firmly with the surrounding skin, is not easy to fall off, and can prevent water immersion, which is an advantage that general external medications do not have.

[0047]

[0048] ③ Because the scab forms quickly and firmly, it reduces the chance of infection.

[0049] ④ It is simple, economical, convenient, widely applicable, and can save a lot of treatment time, manpower, and material resources.

[0050] The present invention, by adopting the above-described technical solution, has the following beneficial effects:

[0051] (1) This invention uses spider webs and wound-hemostatic powder, perfectly applying the wisdom of ancient sages. Spider webs are mainly used for stopping bleeding, especially wounds. The principle of spider web hemostasis in modern Western medicine is that the substance called "serine" contained in spider webs has a hemostatic effect and spider webs have high water absorption. We also found the traditional Chinese medicine formula for wound-hemostatic powder, which stops bleeding and promotes tissue regeneration. We extracted the effective components or medicinal materials of both for stopping bleeding. This innovative combination of Chinese and Western medicine reflects the uniqueness of our product. At the same time, it breaks the material limitations of the current bandages on the market and prepares corresponding products for wound bleeding problems, providing a convenient and reliable treatment solution for patients with wound bleeding.

[0052] (2) Specifically targeting bleeding from wounds, the serine contained in spider webs has strong hemostatic properties. When the serine on the spider web comes into contact with blood, it quickly coagulates platelets in the blood to form a thrombus, thereby achieving the purpose of stopping the bleeding. Jin Chuang Zhi Xue San (a traditional Chinese medicine formula) has appeared multiple times in various ancient Chinese medical texts. It is made from weathered stone, Qilin blood, and chicken eggs, and is mainly used to treat injuries, having the effects of relieving pain from dry sores and promoting tissue regeneration. With the combination of these two medications, along with the advantages of adhesive bandages such as pressure-based hemostasis and breathable material to prevent infection, the therapeutic effect on bleeding from wounds will be more significant, effectively promoting wound hemostasis, wound healing, and preventing wound infection. Attached Figure Description

[0053] Figure 1 This is a schematic diagram of the structure of the adhesive bandage of the present invention;

[0054] Figure 2 This is a flowchart of the preparation method of the present invention;

[0055] Figure 3 These are pathological slide images of three sets of specimens from this invention.

[0056] In the attached diagram, 1-drug core covering film, 2-absorbent composite drug core, 3-medical pressure-sensitive adhesive, and 4-elastic fabric backing. Detailed Implementation

[0057] To make the objectives, technical solutions, and advantages of the present invention clearer, the present invention will be further described in detail below with reference to the accompanying drawings and preferred embodiments. However, it should be noted that many details listed in the specification are merely to provide the reader with a thorough understanding of one or more aspects of the present invention, and these aspects of the invention can be implemented even without these specific details.

[0058] like Figure 1 As shown, the spider web solid bandage for treating bleeding wounds includes a medicated core covering film 1, an absorbent medicated core 2, a medical pressure-sensitive adhesive 3, and an elastic fabric backing 4. The absorbent medicated core 2 is placed above the medicated core covering film (1), the medical pressure-sensitive adhesive 3 is placed over the absorbent medicated core 2, and the elastic fabric backing 4 is placed over the medical pressure-sensitive adhesive 3. The absorbent medicated core 2 is composed of a spider web and a wound-healing powder. The wound-healing powder is placed on the spider web. The spider web stops bleeding and absorbs water, acting as an absorbent pad to absorb blood exudation from the wound. The wound-healing powder stops bleeding, reduces inflammation, promotes tissue regeneration, and facilitates wound healing. The medicated core covering film 1 uses a polyethylene film to cover the medicated core to prevent the medicated core from adhering to the wound. The absorbent medicated core 2 is composed of biomimetic microfibers and a wound-healing powder, with the wound-healing powder sprayed onto the biomimetic microfibers.

[0059] This adhesive bandage is primarily used for the care of small, clean wounds, abrasions, lacerations, and other superficial bleeding wounds that do not require sutures and have a clean, neat cut with minimal bleeding. When choosing a medicated adhesive bandage, be aware of any potential allergies to the medication and select one that meets your individual needs. The bandages are individually packaged to ensure they are clean, hygienic, and free from bacterial contamination.

[0060] Cover the medication core with polyethylene film to prevent it from adhering to the wound.

[0061] ② The core of the medicine consists of a spider web and a wound-healing powder. The spider web stops bleeding from dry sores and has strong water absorption, so it can be used as an absorbent pad to absorb blood seeping from the wound. The wound-healing powder stops bleeding, reduces inflammation, promotes tissue regeneration, and accelerates wound healing.

[0062] ③ Apply medical pressure-sensitive adhesive, which has strong adhesion and allows the bandage to adhere tightly to the wound and not easily slip off.

[0063] ④ The elastic fabric backing is highly elastic, prevents curling at the edges, and is breathable and does not suffocate the skin. It has countless tiny pores that are invisible to the naked eye, allowing it to breathe and be gentle on the skin. While blocking external bacteria, it also prevents the growth and proliferation of bacteria such as tetanus bacteria caused by an anaerobic environment, which can affect wound healing. The strong elasticity allows the bandage to adhere tightly to the skin, ensuring that the wound is in full contact with the medication and promoting wound healing. At the same time, wrapping the bandage with it also has a pressure-stopping effect, promoting hemostasis. The highly elastic fabric makes the bandage very waterproof, and it is not easy for water to penetrate in daily life.

[0064] Precautions: If the wound is small, flat, not bleeding continuously, and clean, it is fine to apply a band-aid or adhesive bandage directly if there are no other options. However, if there is debris, broken glass, or other dirt on the wound, it is necessary to clean and disinfect the wound before applying a band-aid or adhesive bandage. Otherwise, secondary wound infection may easily occur.

[0065] Here are some types of wounds that are not suitable for bandages:

[0066] ① Inflamed wounds: Band-aids are not breathable or absorbent. If the wound is already infected, or has secretions or pus, applying a band-aid will affect the absorption and drainage of secretions and pus, which is not conducive to wound healing.

[0067] ② Unclean wounds: If the wound is not clean or contains foreign objects, applying a band-aid can easily cause infection.

[0068] ③ Large wounds: The cotton pad of a band-aid is not large enough to be effective for large, bleeding wounds.

[0069] ④ Deep and narrow wounds: such as nails, glass shards, insect stings, etc. These wounds are not easy to clean and are prone to infection, so they are not suitable for applying adhesive bandages.

[0070] How to use:

[0071] ① Clean the wound before applying the dressing to ensure there are no foreign objects inside. You can gently rinse the wound with saline solution or clean water, and then gently dry it with a clean cotton swab or gauze.

[0072] ② The wound area should not exceed the area of ​​the cotton pad. If the wound is too large, the adhesive bandage cannot completely cover it, which may increase the risk of infection. In this case, more professional dressings or bandages should be used.

[0073] ③ Keep the bandage dry. This bandage is waterproof in daily life. If it gets wet or soiled, replace it immediately. Also change the bandage after bathing or soaking in water to prevent infection.

[0074] like Figure 2 As shown, the method for making a solid spider web bandage for treating bleeding wounds involves collecting spider webs as an absorbent pad, preparing a wound-hemostatic powder, spraying the powder onto the absorbent pad to form a medicated core, placing the medicated core on a medicated core covering film 1, placing medical pressure-sensitive adhesive 3 and elastic cloth backing 4 on the medicated core at the same time, setting pressure to press together, then punching the film, packaging and sterilizing the box to complete the preparation.

[0075] Research on the toxic side effects, feasibility and efficacy of adhesive bandages

[0076] To test the hemostatic effect of each component of the product, its curative effects such as relieving pain, promoting granulation tissue growth, and accelerating wound healing, and to ensure the safety and reliability of the product, our team decided to use a controlled experiment to obtain true and effective data. The controlled experiment method is as follows:

[0077] ① Control of the curative effect of Jinchuang Zhixue Powder: After depilating healthy Kunming mice, their skin was exposed. They were subjected to superficial acupuncture wounds of the same degree and the same wound surface area, and after disinfecting the wounds, they were evenly divided into two groups. One group used Jinchuang Zhixue Powder dressing, and the other group used ordinary wound plasters. The hemostatic effect, dry wound pain relief, granulation tissue growth, etc. of Jinchuang Zhixue Powder were compared and analyzed, as well as whether there were any adverse reactions in the wounds of the mice after recovery.

[0078] ② Control of the curative effect of spider webs: After depilating healthy Kunming mice, their skin was exposed. They were subjected to superficial acupuncture wounds of the same degree and the same wound surface area, and after disinfecting the wounds, they were evenly divided into two groups. In one group, spider webs were wound around the injured parts of the mice, and in the other group, ordinary wound plasters were used. The hemostatic effect of spider webs was compared and analyzed, as well as whether there were any adverse reactions in the wounds of the mice after recovery.

[0079] ③ Control of the curative effect of the product: After initially obtaining the experimental product, healthy Kunming mice were depilated and their skin was exposed. They were subjected to superficial acupuncture wounds of the same degree and the same wound surface area, and after disinfecting the wounds, they were evenly divided into two groups. One group used Jinchuang Zhixue Powder + spider web wound plasters, and the other group used ordinary wound plasters. The hemostatic situation and wound recovery of the mice's wounds were compared and analyzed, as well as whether there were any adverse reactions in the wounds of the mice after recovery.

[0080] ④ Blank control: After depilating healthy Kunming mice, their skin was exposed. They were subjected to superficial acupuncture wounds of the same degree and the same wound surface area, and the wounds were disinfected. The hemostatic situation and wound recovery of the mice's wounds were observed, as well as whether there were any adverse reactions in the wounds of the mice after recovery.

[0081] Through the four groups of controlled experiments, it was determined that this product has excellent effects on rapid hemostasis, dry wound pain relief, granulation tissue growth, and accelerating wound healing, can effectively solve the problem of bleeding from Jinchuang, and has a good prognosis.

[0082] Using the technology that combines traditional theory guidance and modern science and technology, applying the traditional prescription of Jinchuang Zhixue Powder and the ancient literature research on spider webs, and since this product is consistent with the working mode of current wound plasters, we sought the help of modern wound plaster manufacturing technology to combine the hemostatic effect of spider webs with Jinchuang Zhixue Powder. Under the guidance of modern science and technology, a reasonable preparation plan can be quickly and effectively obtained. The project was implemented according to the plan, and with the guidance of the teacher, the preparation process of the wound plaster was quickly completed. Without affecting the efficacy, the cost was minimized. Moreover, this product is easy to replace, promotes wound healing, is conducive to the appropriate activities of patients, and promotes the early recovery of patients.

[0083] This project used 100 healthy Kunming mice as experimental subjects. The study investigated the effects of spider webs and a traditional Chinese medicine formula (Jin Chuang Zhi Xue San) on stopping bleeding from wounds. The formula was found to be highly effective in stopping bleeding. Based on this principle, a solid adhesive bandage was developed. A controlled experiment was conducted. Figure 3 As shown, four controlled experiments will be conducted to analyze the hemostatic, analgesic, and tissue-regenerating effects of spider webs and Jin Chuang Zhi Xue San (a traditional Chinese medicine formula for treating superficial wounds). A solid adhesive bandage with specific indications will be developed to address the problem of bleeding from wounds, achieving hemostasis, tissue regeneration, analgesia, and wound healing. This will enrich the theoretical research on spider webs and Jin Chuang Zhi Xue San, providing a theoretical basis and practical evidence for treating bleeding from wounds, and demonstrating the important role of this specific adhesive bandage in the treatment of superficial wound bleeding. Figure 3 A is the blank control (knife cut, wound left untreated). Figure 3 C stands for spider web processing. Figure 3 B is treated with Jin Chuang Zhi Xue San (a traditional Chinese medicine formula), which leads to the conclusion that both the spider web and Jin Chuang Zhi Xue San promote wound healing.

[0084] This project aims to create a solid bandage with spider web and wound-healing powder as its main ingredients. It combines traditional Chinese medicine theory with modern technology, drawing upon TCM principles related to wound bleeding and spider webs. The spider web absorbent pad and the bandage's pressure work together to quickly stop bleeding. The wound-healing powder, as a dressing, promotes tissue regeneration, stops bleeding, reduces inflammation, relieves swelling and pain, and accelerates wound healing. Combined with modern bandage manufacturing technology, this results in a solid bandage product with excellent hemostatic effects, addressing common wound bleeding problems. This project is based on extensive theoretical research, practical investigations, and consultations, comparing the product with existing products on the market. The results show that the "wound-healing powder + spider web" solid bandage possesses novel materials, advanced effects, and efficient preparation. During the project, emphasis was placed on the theoretical research of spider web and wound-healing powder, as well as the selection of the bandage's surface material and its design. After confirming its effectiveness, lack of toxic side effects, and safety, the product was developed, meeting both public health needs and practical requirements such as appearance and waterproofing.

[0085] Matters not covered in this invention are common knowledge.

[0086] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A solid spider web-shaped bandage for treating bleeding from wounds, characterized in that: It includes a drug core cover film (1), a water-absorbing combination drug core (2), a medical pressure-sensitive adhesive (3), and an elastic fabric backing (4). The water-absorbing combination drug core (2) is placed on top of the drug core cover film (1), the medical pressure-sensitive adhesive (3) is placed on top of the water-absorbing combination drug core (2), and the elastic fabric backing (4) is placed on top of the medical pressure-sensitive adhesive (3).

2. The solid hemostatic bandage for treating bleeding wounds according to claim 1, characterized in that: The absorbent combination core (2) consists of a spider web and a wound hemostatic powder. The wound hemostatic powder is placed on the spider web. The spider web stops bleeding and absorbs water, and acts as an absorbent pad to absorb the blood seeping from the wound. The wound hemostatic powder stops bleeding, reduces inflammation, promotes tissue regeneration, and promotes wound healing.

3. The solid hemostatic bandage for treating bleeding from wounds according to claim 1, characterized in that: (1) A polyethylene film is used to cover the medicated core to prevent it from sticking to the wound.

4. The solid hemostatic bandage for treating bleeding from wounds according to claim 3, characterized in that: The absorbent combination core (2) is composed of biomimetic microfibers and Jin Chuang Zhi Xue San (a traditional Chinese medicine for treating hemorrhage). Jin Chuang Zhi Xue San is sprayed onto the biomimetic microfibers.

5. The method for manufacturing the solid hemostatic bandage for treating bleeding wounds according to claims 1-4, characterized in that: Spider webs were collected as absorbent pads to prepare Jin Chuang Zhi Xue San (a traditional Chinese medicine for treating hemorrhage). Jin Chuang Zhi Xue San was sprayed onto the absorbent pads to form a core. The core was placed on the core covering film (1). Medical pressure-sensitive adhesive (3) and elastic cloth backing (4) were placed on the core at one time. Pressure was set and pressed. Then, the core was punched and packaged in a sterilized box to complete the preparation.

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