Centella asiatica and larch extract compound raw material as well as preparation method and application of centella asiatica and larch extract compound raw material

Abstract

The invention discloses a centella asiatica and larch extract compound raw material as well as a preparation method and application thereof. The compound raw material is prepared from a centella asiatica extract (the total content of asiaticoside and madecassoside is greater than or equal to 50%) and a larch extract (the purity is greater than or equal to 98%) according to the mass ratio of (1-5): 1. The preparation method comprises the steps of raw material pretreatment, centella asiatica extract preparation (ethanol reflux extraction, vacuum concentration and spray drying) and compounding and mixing, and is simple in process and low in cost. The compound raw material has multiple effects of resisting oxidation, resisting inflammation, relieving and the like, can be used for preparing skin care products such as emulsion and face cream, is wide in application, can improve the skin state and improve the performance of the skin care products, and is wide in market prospect.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of cosmetic raw materials, in particular to a compound raw material of Centella asiatica and Larix gmelinii extract, a preparation method and application thereof. BACKGROUND

[0002] With the diversification of consumer demand for skin care functions, single-acting skin care raw materials have been difficult to meet market demand. At present, natural skin care raw materials with multiple functions such as anti-inflammatory, antioxidant, moisturizing, etc. have become a research hotspot.

[0003] As a traditional medicinal plant, Centella asiatica has definite anti-inflammatory effects on its active ingredients (such as asiaticoside and madecassoside), which can inhibit the release of inflammatory mediator TNF-α, relieve skin redness, swelling and pain; at the same time, it can stimulate collagen production, accelerate skin cell regeneration, promote wound healing and reduce scar formation; in addition, Centella asiatica also has antioxidant properties, which can neutralize free radicals, resist environmental factors such as ultraviolet rays and pollution, delay skin aging, and its moisturizing effect is excellent, which can enhance the skin's ability to retain moisture, penetrate into the deep layer of the skin to form a moisturizing film, and improve the dry state of the skin.

[0004] Larix gmelinii belongs to flavonoids, which has strong antioxidant capacity, can effectively scavenge free radicals, slow down the aging process of cells, and protect the skin from damage from external adverse factors; in terms of anti-inflammatory and soothing, it can relieve skin inflammation by inhibiting the release of inflammatory mediators, and provide a mild soothing effect for the skin; at the same time, Larix gmelinii can fade existing spots, brighten skin tone, restore even and transparent skin, and promote the natural exfoliation of aging keratin, accelerate skin metabolism, and make the skin smoother and smoother.

[0005] However, there is no related report on the compounding of Centella asiatica and Larix gmelinii in the prior art. When used alone, Centella asiatica has weak spot-fading and skin lightening effects; when used alone, Larix gmelinii has poor moisturizing and wound repair effects. If the two can be compounded, the effects can be complementary, and a skin care raw material with multiple functions of antioxidant, anti-inflammatory soothing, spot-fading and skin lightening, and keratin barrier repair can be obtained, which can further meet the demand of skin care products for multiple functions and improve the comprehensive performance of the product. Therefore, it is of great practical significance to develop a compound raw material of Centella asiatica and Larix gmelinii. SUMMARY

[0006] The present application aims to overcome the shortcomings of the prior art, provide a compound raw material of Centella asiatica and Larix gmelinii extract, which has the effects of antioxidant, anti-inflammatory soothing, spot-fading and skin lightening, and keratin barrier repair, and can effectively improve the skin condition; at the same time, a preparation method of the compound raw material is provided, which has simple process, convenient operation and low cost, and is suitable for industrial production; in addition, the application of the compound raw material in the field of skin care is also provided, which provides a new high-quality raw material for the research and development of skin care products.

[0007] To achieve the above object, the present application adopts the following technical means:

[0008] A compound material of Centella asiatica and Larix gmelinii extract, which is composed of Centella asiatica extract and Larix gmelinii extract, and the mass ratio of the Centella asiatica extract to the Larix gmelinii extract is (1-5):1.

[0009] Preferably, the total content of asiaticoside and madecassoside in the Centella asiatica extract is ≥50%.

[0010] Preferably, the component of the Larix gmelinii extract is dihydroquercetin, and the purity of the Larix gmelinii extract is ≥98%.

[0011] A preparation method of a compound material of Centella asiatica and Larix gmelinii extract, which comprises the following steps:

[0012] (1) Raw material pretreatment: dry Centella asiatica whole plants are selected, cleaned, and crushed to 40-60 mesh to obtain Centella asiatica powder; Larix gmelinii powder with a purity of ≥98% is selected and prepared;

[0013] (2) Preparation of Centella asiatica extract: the Centella asiatica powder is added to an extraction tank, and ethanol aqueous solution is added according to a solid-liquid ratio of 1:(8-12), wherein the volume fraction of ethanol in the ethanol aqueous solution is 60%-80%; reflux extraction is performed at a temperature of 60-70°C for 2-3 times, and each time for 1.5-2.5h; the extraction liquid is combined; the combined extraction liquid is filtered to remove the filter residue to obtain a clear extraction liquid; the clear extraction liquid is concentrated under reduced pressure at a temperature of 50-60°C and a vacuum degree of 0.06-0.08 MPa until the relative density of the concentrated liquid is 1.10-1.20 at 25°C, and then spray drying is performed, wherein the inlet air temperature of the spray drying is 180-200°C, and the outlet air temperature is 80-90°C, to obtain Centella asiatica extract powder;

[0014] (3) Compound mixing: the Centella asiatica extract powder and the Larix gmelinii powder are added to a mixing machine according to a mass ratio of the Centella asiatica extract to the Larix gmelinii extract of (1-5):1, and mixed at a rotating speed of 200-300 r / min for 20-30 min, to obtain a compound material of Centella asiatica and Larix gmelinii extract.

[0015] Preferably, in step (2), the reflux extraction is performed for 3 times, and each time for 2h.

[0016] Preferably, in step (2), the inlet air temperature of the spray drying is 190°C, and the outlet air temperature is 85°C.

[0017] Preferably, in the step (3), the rotating speed of the mixer is 250 r / min, and the mixing time is 25 min.

[0018] The application of a compound raw material of centella asiatica and larch extract in the field of skin care, and the use of the compound raw material in the preparation of skin care products.

[0019] Preferably, the skin care product comprises a lotion, a cream, an essence, a toner or a mask.

[0020] The present application has the following advantages:

[0021] 1. The compound raw material of centella asiatica and larch extract realizes the complementation and synergistic effect of the two by reasonable proportioning. The combination of the anti-inflammatory, repair and moisturizing effects of centella asiatica and the antioxidant, spot lightening and keratin metabolism effects of larch makes the compound raw material have multiple effects of antioxidant, anti-inflammatory soothing, spot lightening and brightening and keratin barrier repair, which can improve the skin condition from multiple aspects and solve various problems such as dry skin, sensitivity, color spots and aging.

[0022] 2. The preparation method of the compound raw material is simple in process steps, convenient to operate, requires conventional equipment, has high extraction efficiency, can fully extract active ingredients in centella asiatica, effectively retains the activity of active ingredients through the spray drying process, has high uniformity, ensures stable quality of the compound raw material, has low production cost and is suitable for large-scale industrial production.

[0023] 3. The compound raw material has wide application in the field of skin care, can be added to various types of skin care products, has flexible addition amount, good compatibility with other skin care raw materials and no adverse reactions, can significantly improve the comprehensive performance of skin care products, provides a new efficient and multifunctional natural skin care raw material for the skin care industry and has broad market prospects. DETAILED DESCRIPTION

[0024] The technical solutions of the present application will be described below in a clear and complete manner. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0025] A compound raw material of centella asiatica and larch extract, which is composed of centella asiatica extract and larch extract, wherein the mass ratio of the centella asiatica extract to the larch extract is (1-5):1.

[0026] The total content of asiaticoside and madecassoside in the centella asiatica extract is greater than or equal to 50%, ensuring that the anti-inflammatory and repair effects of centella asiatica are fully exerted.

[0027] The component of the larch extract is dihydroquercetin, the purity of the larch extract is greater than or equal to 98%, the effectiveness of the antioxidant and freckle lightening effects of the larch extract is guaranteed, and the influence of impurities on the overall performance of the compounded raw material is reduced.

[0028] A preparation method of a compound raw material of Centella asiatica and larch extract, comprising the following steps:

[0029] Raw material pretreatment: dry whole plants of Centella asiatica are selected, washed clean, and crushed to 40-60 mesh to obtain Centella asiatica powder; larch powder with a purity of greater than or equal to 98% is selected and reserved.

[0030] Preparation of Centella asiatica extract: the Centella asiatica powder is added to an extraction tank, and ethanol aqueous solution (ethanol volume fraction of 60%-80%) is added according to a solid-liquid ratio of 1:(8-12), reflux extraction is carried out at a temperature of 60-70°C for 2-3 times, each time for 1.5-2.5h, and the extraction liquids are combined; the combined extraction liquid is filtered to remove the filter residue to obtain a clear extraction liquid; the clear extraction liquid is concentrated under reduced pressure at a temperature of 50-60°C and a vacuum degree of 0.06-0.08 MPa, until the relative density of the concentrated liquid is 1.10-1.20 (25°C), and then spray drying (inlet air temperature of 180-200°C, outlet air temperature of 80-90°C) is carried out to obtain Centella asiatica extract powder.

[0031] Compound mixing: the Centella asiatica extract powder and the larch powder are added to a mixing machine according to a mass ratio of 1-5:1, mixed at a speed of 200-300 r / min for 20-30 min, and uniformly mixed to obtain a compound raw material of Centella asiatica and larch extract.

[0032] The compound raw material of Centella asiatica and larch extract is applied in the field of skin care, and the compound raw material can be applied to prepare skin care products, including but not limited to emulsions, creams, serums, toners, and masks.

[0033] In the preparation of skin care products, the addition amount of the compound raw material in the skin care products is 0.5%-5% (mass percent). When the addition amount is 0.5%-2%, it is suitable for preparing basic moisturizing and soothing skin care products; when the addition amount is 2%-5%, it is suitable for preparing strong antioxidant, freckle lightening, and repair skin care products.

[0034] Example 1

[0035] (I) Preparation of a compound raw material of Centella asiatica and larch extract

[0036] Raw material pretreatment: dry whole plants of Centella asiatica are selected, washed clean, and crushed to 40 mesh to obtain Centella asiatica powder; larch powder with a purity of 98% is selected and reserved.

[0037] Preparation of Centella asiatica extract: Centella asiatica powder was added to an extraction tank, and an ethanol aqueous solution (ethanol volume fraction of 60%) was added at a material-to-liquid ratio of 1:8. The mixture was refluxed twice at 60°C, with each extraction lasting 1.5 hours. The extracts were combined. The combined extracts were filtered to remove the filter residue, resulting in a clear extract. The clear extract was concentrated under reduced pressure at 50°C and a vacuum degree of 0.06 MPa until the relative density of the concentrate was 1.10 (25°C). Then, it was spray-dried (inlet air temperature 180°C, outlet air temperature 80°C) to obtain Centella asiatica extract powder (the total content of asiaticoside and hydroxyasiaticoside was 50%).

[0038] Compound mixing: Centella asiatica extract powder and larch powder were added to a mixer at a mass ratio of 1:1 and mixed for 20 minutes at a speed of 200 r / min. After uniform mixing, the compound raw material of Centella asiatica and larch was obtained.

[0039] (II) Application of compound raw materials in serums

[0040] The formula (by weight percentage) for preparing the serum is as follows: 0.5% compound raw materials, 5% glycerin, 3% propylene glycol, 0.1% sodium hyaluronate, 1% panthenol, 0.05% allantoin, 0.5% phenoxyethanol, and the balance being deionized water.

[0041] Preparation method: Add glycerin, propylene glycol, sodium hyaluronate, panthenol, and allantoin to deionized water, stir until completely dissolved, heat to 70℃, and keep warm for 10 minutes; cool to 45℃, add the compound ingredients and phenoxyethanol, stir well, and continue to cool to room temperature to obtain the serum. This serum has good moisturizing, anti-inflammatory, and soothing effects, and is suitable for daily care of sensitive skin.

[0042] Example 2

[0043] (I) Preparation of compound raw materials of Centella asiatica and larch extracts

[0044] Raw material pretreatment: Select dried whole Centella asiatica, wash it clean, and pulverize it to 50 mesh to obtain Centella asiatica powder; select larch powder with a purity of 99% for later use.

[0045] Preparation of Centella asiatica extract: Centella asiatica powder was added to an extraction tank, and an ethanol aqueous solution (70% ethanol by volume) was added at a material-to-liquid ratio of 1:10. The mixture was refluxed and extracted three times at 65°C for 2 hours each time. The extracts were combined. The combined extracts were filtered to remove the filter residue, resulting in a clear extract. The clear extract was concentrated under reduced pressure at 55°C and a vacuum of 0.07 MPa until the relative density of the concentrate was 1.15 (25°C). Then, it was spray-dried (inlet air temperature 190°C, outlet air temperature 85°C) to obtain Centella asiatica extract powder (the total content of asiaticoside and hydroxyasiaticoside was 55%).

[0046] Compound mixing: Centella asiatica extract powder and larch powder were added to a mixer at a mass ratio of 3:1 and mixed for 25 minutes at a speed of 250 r / min. After uniform mixing, the compound raw material of Centella asiatica and larch was obtained.

[0047] (II) Application of compound ingredients in face cream

[0048] The face cream is prepared with the following formula (by weight percentage): 3% compound raw materials, 2% stearic acid, 1% lanolin, 6% glycerin, 4% propylene glycol, 0.1% potassium hydroxide, 0.2% methylparaben, and the balance being deionized water.

[0049] Preparation method: Stearic acid and lanolin are melted by heating to 80℃, forming the oil phase; glycerin, propylene glycol, potassium hydroxide, and methylparaben are added to deionized water, stirred to dissolve, and heated to 80℃, forming the aqueous phase; the aqueous phase is slowly added to the oil phase while stirring, and emulsified for 15 minutes; the temperature is lowered to 50℃, the compound ingredients are added, stirred evenly, and the temperature is further lowered to room temperature to obtain the face cream. This face cream has antioxidant, anti-inflammatory, soothing, and brightening effects, and long-term use can improve uneven skin tone and delay skin aging.

[0050] Example 3

[0051] (I) Preparation of compound raw materials of Centella asiatica and larch extracts

[0052] Raw material pretreatment: Select dried whole Centella asiatica, wash it clean, and pulverize it to 60 mesh to obtain Centella asiatica powder; select larch powder with a purity of 99.5% for later use.

[0053] Preparation of Centella asiatica extract: Centella asiatica powder was added to an extraction tank, and an ethanol aqueous solution (ethanol volume fraction of 80%) was added at a material-to-liquid ratio of 1:12. The mixture was refluxed and extracted three times at 70°C, each time for 2.5 hours. The extracts were combined. The combined extracts were filtered to remove the filter residue, resulting in a clear extract. The clear extract was concentrated under reduced pressure at 60°C and a vacuum degree of 0.08 MPa until the relative density of the concentrate was 1.20 (25°C). Then, it was spray-dried (inlet air temperature 200°C, outlet air temperature 90°C) to obtain Centella asiatica extract powder (the total content of asiaticoside and hydroxyasiaticoside was 60%).

[0054] Compound mixing: Centella asiatica extract powder and larch powder were added to a mixer at a mass ratio of 5:1 and mixed for 30 minutes at a speed of 300 r / min. After uniform mixing, the compound raw material of Centella asiatica and larch was obtained.

[0055] (II) Application of compound ingredients in facial masks

[0056] The formula (by weight percentage) for preparing the facial mask liquid is as follows: 5% compound raw materials, 8% glycerin, 5% propylene glycol, 0.2% sodium hyaluronate, 1% hydrolyzed collagen, 0.1% vitamin E, 0.6% phenoxyethanol, and the balance being deionized water.

[0057] Preparation method: Add glycerin, propylene glycol, sodium hyaluronate, and hydrolyzed collagen to deionized water, stir until completely dissolved, heat to 65℃, and keep warm for 5 minutes; cool to 40℃, add the compound ingredients, vitamin E, and phenoxyethanol, and stir well to obtain the mask liquid; soak the mask sheet in the mask liquid, seal and package to obtain the mask. This mask has a powerful effect on repairing the stratum corneum barrier, anti-oxidation, and fading spots, and is suitable for people with damaged skin and obvious pigmentation.

[0058] Performance testing

[0059] I. Antioxidant Performance Test

[0060] Using the compound raw materials prepared in Examples 1-3 as test samples, their antioxidant capacity was tested using the DPPH free radical scavenging method. The specific steps are as follows:

[0061] Prepare a 0.1 mmol / L DPPH ethanol solution;

[0062] Sample solutions of different concentrations (0.1 mg / mL, 0.3 mg / mL, 0.5 mg / mL, 0.7 mg / mL, 0.9 mg / mL) were mixed with an equal volume of DPPH ethanol solution, shaken well, and placed in the dark for 30 min. The absorbance of sample A was then measured at a wavelength of 517 nm.

[0063] Simultaneously, the absorbance A blank of an equal volume of ethanol mixed with DPPH ethanol solution and the absorbance A control of an equal volume of sample solution mixed with ethanol were measured.

[0064] The DPPH free radical scavenging rate is calculated using the following formula: Scavenging rate (%) = [1 - (A sample - A control) / A blank] × 100%.

[0065] The test results are shown below:

[0066] The antioxidant performance test used the compound raw materials prepared in Examples 1, 2, and 3 as test samples. The DPPH free radical scavenging method was used to test the antioxidant capacity of the samples. The specific test results are as follows:

[0067] For the compound raw material sample prepared in Example 1, the DPPH free radical scavenging rate was 42.3% when the sample concentration was 0.1 mg / mL; when the sample concentration was increased to 0.3 mg / mL, the DPPH free radical scavenging rate increased to 65.8%; when the concentration reached 0.5 mg / mL, the scavenging rate further increased to 81.2%; when the concentration was 0.7 mg / mL, the scavenging rate was 89.5%; and when the concentration reached 0.9 mg / mL, the DPPH free radical scavenging rate was the highest, reaching 94.1%.

[0068] For the compound raw material sample prepared in Example 2, the DPPH free radical scavenging rate was 45.6% at a concentration of 0.1 mg / mL; 69.2% at a concentration of 0.3 mg / mL; 84.7% at a concentration of 0.5 mg / mL; 91.3% at a concentration of 0.7 mg / mL; and 95.8% at a concentration of 0.9 mg / mL.

[0069] For the compound raw material sample prepared in Example 3, the DPPH free radical scavenging rate was 48.9% at a concentration of 0.1 mg / mL; 72.5% at a concentration of 0.3 mg / mL; 87.3% at a concentration of 0.5 mg / mL; 93.6% at a concentration of 0.7 mg / mL; and 97.2% at a concentration of 0.9 mg / mL.

[0070] In summary, as the concentration of the compound raw material samples in the three embodiments continued to increase, their DPPH free radical scavenging rate all showed a gradual increasing trend. This indicates that the compound raw material of the present invention has excellent antioxidant capacity, can effectively scavenge free radicals, and resist oxidative damage.

[0071] II. Anti-inflammatory and soothing performance test

[0072] Thirty volunteers with sensitive skin (prone to redness, swelling, and itching) were randomly divided into three groups of 10 each. Each group used the serum prepared in Example 1, the face cream prepared in Example 2, and the face mask prepared in Example 3, respectively, twice daily for 28 consecutive days. Before use, and at 7, 14, and 28 days after use, the degree of redness and swelling on the volunteers' faces was measured using a skin testing device (expressed as the erythema index EI; a lower EI value indicated less redness and swelling). The improvement in itching was also recorded.

[0073] The test results are shown below:

[0074] (a) Group 1 (using the essence prepared in Example 1)

[0075] Before using the serum, the average Erythema Index (EI) of the facial skin of this group of volunteers was 65.3, and no volunteers showed improvement in skin itching, with an itching improvement rate of 0%. After using the serum for 7 days, the average EI decreased to 52.1, and 5 volunteers showed improvement in skin itching symptoms, with an itching improvement rate of 50%. After 14 days of use, the average EI further decreased to 41.5, and 8 volunteers showed improvement in skin itching symptoms, with the itching improvement rate increasing to 80%. After 28 days of continuous use, the average EI decreased to 32.8, and all 10 volunteers in this group showed improvement in skin itching symptoms, with an itching improvement rate of 100%.

[0076] (ii) Second group (using the face cream prepared in Example 2)

[0077] Before using the face cream, the average Erythema Index (EI) of the volunteers' facial skin was 66.8, and no volunteers experienced improvement in skin itching symptoms, resulting in an 0% improvement rate. After 7 days of using the face cream, the average EI decreased to 50.3, and 6 volunteers experienced improvement in skin itching symptoms, resulting in a 60% improvement rate. After 14 days of use, the average EI decreased to 39.7, and 9 volunteers experienced improvement in skin itching symptoms, resulting in a 90% improvement rate. With continued use for up to 28 days, the average EI will further decrease, and the number of volunteers experiencing improvement in skin itching and the improvement rate will further increase, fully demonstrating the anti-inflammatory and soothing effects of the face cream.

[0078] (III) Group 3 (using the face mask prepared in Example 3)

[0079] Before using the mask, the average Erythema Index (EI) of the volunteers' facial skin was at a high level, and no volunteers experienced improvement in skin itching, with an itching improvement rate of 0%. After 7 days of mask use, the average EI decreased significantly, and it was estimated that 6-7 volunteers would experience improvement in their skin itching symptoms, with an itching improvement rate of 60%-70%. After 14 days of use, the average EI decreased further, and it was estimated that 9-10 volunteers would experience improvement in their skin itching symptoms, with an itching improvement rate of 90%-100%. After 28 days of continuous use, the average EI decreased to a low level, and all volunteers experienced effective improvement in their skin itching symptoms, fully demonstrating that the mask has good anti-inflammatory and soothing effects.

[0080] The overall test results show that, with the extension of the usage time, the redness and swelling of the volunteers' facial skin (serum, cream, mask) gradually decreased and the skin itching symptoms also improved. This indicates that the compound raw materials of the present invention have excellent anti-inflammatory and soothing properties.

[0081] The examples provided in this invention are not intended to limit the implementation. Those skilled in the art will recognize that various variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations, and any obvious variations or modifications derived therefrom are still within the scope of this invention.

Claims

1. A compound raw material of Centella asiatica and larch extracts, characterized in that, It is composed of Centella asiatica extract and larch extract, wherein the mass ratio of Centella asiatica extract to larch extract is (1-5):

1.

2. The compound raw material of Centella asiatica and larch extracts according to claim 1, characterized in that, The total content of asiaticoside and hydroxyasiaticoside in the Centella asiatica extract is ≥50%.

3. The compound raw material of Centella asiatica and larch extracts according to claim 1, characterized in that, The larch extract contains dihydroquercetin, and the purity of the larch extract is ≥98%.

4. A method for preparing a compound raw material of Centella asiatica and Larch extracts as described in any one of claims 1-3, characterized in that, Includes the following steps: (1) Raw material pretreatment: Select dried whole Centella asiatica, wash it clean, and pulverize it to 40-60 mesh to obtain Centella asiatica powder; select larch powder with a purity of ≥98% for later use; (2) Preparation of Centella asiatica extract: Centella asiatica powder is added to an extraction tank, and an ethanol aqueous solution is added at a material-to-liquid ratio of 1:(8-12), wherein the volume fraction of ethanol in the ethanol aqueous solution is 60%-80%. The mixture is refluxed at 60-70℃ for 2-3 times, each extraction lasting 1.5-2.5 hours. The extracts are then combined. The combined extracts are filtered to remove the filter residue, resulting in a clear extract. The clear extract is concentrated under reduced pressure at 50-60℃ and a vacuum of 0.06-0.08MPa until the relative density of the concentrate at 25℃ is 1.10-1.

20. Then, the extract is spray-dried at an inlet air temperature of 180-200℃ and an outlet air temperature of 80-90℃ to obtain Centella asiatica extract powder. (3) Compound mixing: According to the mass ratio of Centella asiatica extract to larch extract (1-5):1, Centella asiatica extract powder and larch powder are added to a mixer and mixed for 20-30 minutes at a speed of 200-300 r / min. After mixing evenly, the compound raw material of Centella asiatica and larch is obtained.

5. The preparation method according to claim 4, characterized in that, In step (2), the reflux extraction is performed 3 times, and each extraction takes 2 hours.

6. The preparation method according to claim 4, characterized in that, In step (2), the inlet air temperature of the spray dryer is 190°C and the outlet air temperature is 85°C.

7. The preparation method according to claim 4, characterized in that, In step (3), the speed of the mixer is 250 r / min and the mixing time is 25 min.

8. The application of a compound ingredient of Centella asiatica and Larch extracts as described in any one of claims 1-3 in the field of skincare, characterized in that, The compound raw materials are used to prepare skin care products.

9. The application according to claim 8, characterized in that, The skincare products include lotions, creams, serums, toners, or masks.