Traditional Chinese medicine composition for relieving pain of whole body and preparation method of traditional Chinese medicine composition

By preparing a traditional Chinese medicine composition containing analgesic, blood-activating, adjuvant, and synergistic conditioning components, the problems of complex ingredients, large side effects, and low transdermal absorption in the treatment of systemic pain have been solved, achieving a highly efficient and safe pain relief effect.

CN121313769APending Publication Date: 2026-01-13GUIZHOU MIAOKANGFU BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202511815022.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-12-04
Publication Date
2026-01-13

AI Technical Summary

Technical Problem

Existing technologies for treating systemic pain have problems such as significant side effects, complex composition, unclear dosage compatibility, low transdermal absorption efficiency, and insufficient safety control.

Method used

A traditional Chinese medicine composition consisting of drug components A, B, and C and excipients is prepared by mixing them in a specific ratio, soaking them in ethanol, and purifying them twice to form a transdermal penetration-enhancing traditional Chinese medicine composition.

Benefits of technology

It achieves clear function and dosage of each component, allowing the drug to directly target the core of pain, enhance analgesia while also taking into account the body's conditioning, has high safety, high transdermal absorption efficiency, and reduces side effects.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a traditional Chinese medicine composition for relieving whole body pain. The traditional Chinese medicine composition is prepared from the following raw materials: a medicine component A, a medicine component B, a medicine component C and auxiliary materials, the medicine component A is a composition for easing pain and activating blood, the medicine component B is an auxiliary synergistic composition, the medicine component C is a synergistic conditioning composition, and the auxiliary material is a transdermal penetration enhancing and synergistic composition. Compared with the prior art, the traditional Chinese medicine composition for relieving the pain of the whole body and the preparation method have the advantages that the traditional Chinese medicine composition is complete in effect and small in harm to the body.
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Description

Technical Field

[0001] This invention relates to traditional Chinese medicine compositions, specifically a traditional Chinese medicine composition and preparation method for relieving systemic pain. Background Technology

[0002] In existing technologies, most treatments for systemic pain involve single-target interventions (such as nonsteroidal anti-inflammatory drugs, which can only relieve inflammatory pain), and have side effects such as gastrointestinal irritation and liver and kidney toxicity.

[0003] While traditional Chinese medicine compound prescriptions emphasize overall conditioning, they suffer from problems such as complex ingredients, unclear dosage and compatibility, and low transdermal absorption efficiency, resulting in unstable efficacy.

[0004] In addition, existing Chinese medicine preparations often neglect the safety control of toxic medicinal materials, posing potential safety hazards. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the above-mentioned technical defects and provide a traditional Chinese medicine composition and preparation method for relieving whole-body pain with complete efficacy and minimal harm to the body.

[0006] To solve the above-mentioned technical problems, the technical solution provided by the present invention is: a traditional Chinese medicine composition for relieving systemic pain, made from the following raw materials: including drug component A, drug component B, drug component C and excipients;

[0007] Drug component A is an analgesic and blood-activating composition, drug component B is an adjuvant synergistic composition, drug component C is a synergistic conditioning composition, and the excipient is a transdermal penetration enhancer and synergistic composition.

[0008] Preferably, the drug component A includes 90-190 parts of Ligusticum chuanxiong, 80-180 parts of Dianthus chinensis, 90-190 parts of Clematis chinensis, 90-190 parts of ants, 50-130 parts of leeches, 60-166 parts of Cinnamomum cassia, 60-160 parts of Spatholobus suberectus, 50-150 parts of Chaenomeles speciosa, 80-150 parts of Liquidambar formosana, 60-160 parts of Bungarus fasciatus, 30-130 parts of centipede, 60-160 parts of Zaocys dhumnades, 30-130 parts of Aconitum carmichaelii, and 60-160 parts of Aconitum carmichaelii.

[0009] Preferably, drug component B includes 30-130 parts of turmeric, 40-140 parts of Baibu Huanyang, 30-130 parts of Baqia, 50-150 parts of Xue Shang Yizhihao, and 20-120 parts of Longxuejie.

[0010] Preferably, the drug component C includes 30-130 parts of Eucommia ulmoides, 40-140 parts of clove, 20-120 parts of Asarum heterotropoides, and 20-120 parts of Poria cocos.

[0011] Preferably, the excipients include 20-90 parts camphor, 10-80 parts laurocapram, 10-80 parts heat sensitizer, 30-100 parts borneol, and 80-220 parts dimethyl benzoate.

[0012] Preferably, the heat sensitizer is menthol ice.

[0013] Another aspect of the present invention discloses a method for preparing a traditional Chinese medicine composition for relieving systemic pain, comprising the following steps:

[0014] S1: Weigh out drug components A, B and C in proportion, mix them, wrap them in gauze, place them in a sealed container, add ethanol and excipients, and seal and soak.

[0015] S2: Filter to remove the dregs, collect the filtrate, and purify the filtrate a second time;

[0016] S3: The traditional Chinese medicine composition is obtained by standing.

[0017] Preferably, 4-6 times the volume of 95% ethanol is added to S1, and the mixture is sealed and soaked for 1-6 months.

[0018] Preferably, the process in S2 is a medicinal soaking and purification.

[0019] The advantages of this invention compared with the prior art are as follows: In this invention, through analgesia and blood circulation promotion + auxiliary enhancement + synergistic conditioning, the functions of each component are clear and the dosage range is clear. Drug component A directly targets the core of pain, component B enhances the analgesic effect, and component C takes into account the body's conditioning. Attached Figure Description

[0020] Figure 1 This is a flowchart illustrating a method for preparing a traditional Chinese medicine composition for relieving systemic pain. Detailed Implementation

[0021] The present invention will now be described in further detail with reference to the accompanying drawings.

[0022] Combined with appendix Figure 1 As shown, a traditional Chinese medicine composition for relieving systemic pain is made from the following raw materials: including drug component A, drug component B, drug component C and excipients; wherein drug component A is an analgesic and blood-activating composition, drug component B is an adjuvant synergistic composition, drug component C is a synergistic conditioning composition, and the excipients are transdermal penetration-enhancing and synergistic compositions.

[0023] In one embodiment:

[0024] Drug component A includes 90-190 parts of Ligusticum chuanxiong, 80-180 parts of Zanthoxylum bungeanum, 90-190 parts of Clematis chinensis, 90-190 parts of ants, 50-130 parts of leeches, 60-166 parts of Cinnamomum cassia, 60-160 parts of Spatholobus suberectus, 50-150 parts of Chaenomeles speciosa, 80-150 parts of Liquidambar formosana, 60-160 parts of Bungarus fasciatus, 30-130 parts of Scolopendra subspinipes, 60-160 parts of Zaocys dhumnades, 30-130 parts of Aconitum carmichaelii, and 60-160 parts of Aconitum carmichaelii.

[0025] In one embodiment:

[0026] Drug component B includes 30-130 parts of turmeric, 40-140 parts of Baibu Huanyang, 30-130 parts of Baqia, 50-150 parts of Xue Shang Yizhihao, and 20-120 parts of Longxuejie.

[0027] In one embodiment:

[0028] Drug component C includes 30-130 parts of Eucommia ulmoides, 40-140 parts of clove, 20-120 parts of Asarum heterotropoides, and 20-120 parts of Aristolochia debilis;

[0029] In one embodiment:

[0030] The excipients include 20-90 parts camphor, 10-80 parts laurocapram, 10-80 parts heat sensitizer, 30-100 parts borneol, and 80-220 parts dimethyl sulfoxide;

[0031] The heat sensitizer is menthol;

[0032] In specific implementation, this invention includes the following steps:

[0033] S1: Weigh out drug components A, B and C in proportion, mix them, wrap them in gauze, place them in a sealed container, add ethanol and excipients, and seal and soak.

[0034] S2: Filter to remove the dregs, collect the filtrate, and purify the filtrate a second time;

[0035] S3: The traditional Chinese medicine composition is obtained by standing, wherein 4-6 times the volume of 95% ethanol is added to S1 and the mixture is sealed and soaked for 1-6 months, and the process in S2 is soaking and purification.

[0036] When using:

[0037] Chuanxiong: It invigorates blood circulation, promotes qi circulation, dispels wind and relieves pain. It is known as "the qi-regulating medicine in the blood" and can alleviate pain caused by meridian obstruction.

[0038] Drilling Wind: Dispels wind and dampness, invigorates blood and relieves pain, especially effective for rheumatic pain and numbness of limbs;

[0039] Iron-wire-penetrating herb: dispels wind and dampness, relaxes muscles and tendons, promotes blood circulation and relieves pain, and improves joint and muscle pain;

[0040] Ants: They nourish the kidneys and replenish essence, promote blood circulation, detoxify and reduce swelling, and help relieve pain from overuse injuries;

[0041] Leeches: They break up blood stasis and promote menstruation, remove blood stasis and eliminate masses, clear deep meridian blockages, and enhance analgesic effects;

[0042] Cinnamon twig: It promotes sweating and relieves muscle tension, warms and unblocks the meridians, assists yang and promotes qi circulation, and relieves pain caused by cold stagnation and blood stasis.

[0043] Chicken blood vine: It invigorates blood circulation, replenishes blood, regulates menstruation, relieves pain, relaxes muscles and tendons, and promotes blood circulation and nourishment, thus reducing the recurrence of pain;

[0044] Papaya: It relaxes muscles and tendons, harmonizes the stomach and dispels dampness, and is especially effective for muscle spasms and limb pain.

[0045] Lulutong: dispels wind and activates blood circulation, promotes diuresis and unblocks meridians, clears the meridians throughout the body, and is suitable for pain in multiple parts of the body;

[0046] White-flowered snake: It dispels wind and unblocks the meridians, calms the nerves and stops spasms, and has significant effects on rheumatic pain and numbness of limbs;

[0047] Centipede: It can calm wind and relieve spasms, unblock meridians and relieve pain, attack toxins and dissipate nodules, and enhance the analgesic effect of stubborn pain;

[0048] Black snake: dispels wind, unblocks meridians, and stops spasms; when combined with white-flowered snake, it enhances the effects of unblocking meridians and relieving pain.

[0049] Aconitum carmichaelii: dispels wind and dampness, warms the meridians and dispels cold, reduces swelling and relieves pain, with strong analgesic effects.

[0050] Aconitum carmichaelii: dispels wind and dampness, warms the meridians and dispels cold, and has anesthesia and analgesia. When combined with Aconitum kusnezoffii, it enhances the relief effect of cold and dampness-related pain.

[0051] Turmeric: It promotes blood circulation, regulates qi, relieves pain, and has anti-inflammatory effects, thus enhancing the core analgesic effect;

[0052] Baibu Huanyang: Clears heat and detoxifies, invigorates blood circulation and removes blood stasis, relieves pain, and helps alleviate inflammatory pain;

[0053] Baqia: It promotes diuresis and removes turbidity, dispels wind and relieves numbness, detoxifies and disperses blood stasis, and reduces inflammation in the painful area;

[0054] Snow-covered Artemisia: dispels wind and dampness, promotes blood circulation and relieves pain, with a strong analgesic effect;

[0055] Dragon's Blood: Promotes blood circulation, relieves pain, removes blood stasis, stops bleeding, promotes tissue regeneration and wound healing, enhances the effects of promoting blood circulation and relieving pain, and promotes local repair;

[0056] Eucommia ulmoides: It nourishes the liver and kidneys, strengthens tendons and bones, and calms the fetus. It also regulates the body's fundamental functions and reduces the recurrence of pain caused by overuse.

[0057] Clove: warms the middle jiao and relieves nausea, dispels cold and relieves pain, warms the kidneys and assists yang, and relieves body aches and pains caused by cold.

[0058] Asarum: It relieves exterior syndromes and dispels cold, dispels wind and relieves pain, clears the orifices, warms the lungs and resolves phlegm, and enhances the effects of dispelling cold and relieving pain;

[0059] Lingxiang: It has the effects of aromatic dampness removal, opening the orifices and refreshing the mind, promoting blood circulation and relieving pain, assisting in unblocking the meridians and improving drug penetration efficiency;

[0060] Camphor: It can clear the orifices, relieve stagnation of qi, dispel foulness, kill insects and relieve itching, reduce swelling and relieve pain, assist in analgesia and promote penetration;

[0061] Lauryl azone: a highly effective transdermal penetration enhancer that promotes the rapid penetration of active pharmaceutical ingredients into the skin barrier;

[0062] Menthol ice (heat sensitizer): enhances skin permeability, accelerates drug absorption, and brings a cooling and comfortable feeling;

[0063] The contents not described in detail in this specification are existing technologies known to those skilled in the art.

[0064] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined in one figure, it does not need to be further defined and explained in subsequent figures.

[0065] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0066] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A traditional Chinese medicine composition for relieving general pain, characterized in that: It is made of the following raw materials: including medicine component A, medicine component B, medicine component C and auxiliary materials; ​ The medicine component A is a pain-relieving and blood-activating composition, the medicine component B is an auxiliary and synergistic composition, the medicine component C is a synergistic regulating composition, and the auxiliary materials are transdermal penetration and synergistic composition.

2. The traditional Chinese medicine composition for relieving general pain according to claim 1, characterized in that: The medicine component A includes Chuanxiong 90-190 parts, Zhuanqifeng 80-180 parts, Tieluoteng 90-190 parts, Ant 90-190 parts, Shuizhi 50-130 parts, Guizhi 60-166 parts, Jixueteng 60-160 parts, Mugua 50-150 parts, Lulutong 80-150 parts, Baihuashen 60-160 parts, Wugong 30-130 parts, Wushen 60-160 parts, Caowu 30-130 parts, and Chuanwu 60-160 parts.

3. The traditional Chinese medicine composition for relieving general pain according to claim 1, characterized in that: The medicine component B includes Rhizoma Curcumae 30-130 parts, Bai Bury Huanyang 40-140 parts, Bajiyin 30-130 parts, Xueshangzizhi 50-150 parts, and Longxuejie 20-120 parts.

4. The traditional Chinese medicine composition for relieving general pain according to claim 1, characterized in that: The medicine component C includes Duzhong 30-130 parts, Dingxiang 40-140 parts, Xixin 20-120 parts, and Lingxiang 20-120 parts.

5. The traditional Chinese medicine composition for relieving general pain according to claim 1, characterized in that: The auxiliary materials include Camphor 20-90 parts, Lauric Nitrone 10-80 parts, heat-sensitive agent 10-80 parts, Bingpian 30-100 parts, and Dimethyl Sulfoxide 80-220 parts.

6. The traditional Chinese medicine composition for relieving general pain according to claim 5, characterized in that: The heat-sensitive agent is peppermint ice.

7. A method for preparing a traditional Chinese medicine composition for relieving general pain according to any one of claims 1-6, characterized in that: It includes the following steps: S1: proportionally weigh the medicine components A, B and C, mix them, wrap them with gauze, put them in a sealed barrel, add ethanol and auxiliary materials for closed soaking; S2: filter to remove the residue, collect the filtrate, and purify the filtrate twice; S3: stand to obtain the traditional Chinese medicine composition.

8. The method of claim 7, wherein the method is for preparing a traditional Chinese medicine composition for relieving general pain. In the S1, 4-6 times of 95% ethanol is added for closed soaking for 1-6 months.

9. The preparation method of the traditional Chinese medicine composition for relieving general pain according to claim 8, characterized in that: In the S2, the process is medicine soaking and purification.