Hair growth and oil control composition and preparation method thereof

Abstract

The invention discloses a hair-growing and oil-controlling composition as well as a preparation method and application thereof. The composition adopts a split-phase design, wherein a phase A comprises a cucumber extract, a ginger extract, a chelating agent and an antioxidant; the phase B comprises ethanol, vegetable oil and an emulsifier; the phase C comprises nicotinamide, a rosemary and grape seed extract and a preservative system; the phase D is prepared from microencapsulated lactobacillus compound bacterium powder and prebiotics; the preparation method comprises the steps of split-phase pretreatment, low-temperature mixing and final introduction of a D phase. Through multiple synergistic effects of plant active components, chemical functional components and probiotics micro-ecological regulation, the shampoo can effectively clean scalp grease, improve hair follicle microcirculation, relieve oxidative stress and regulate scalp flora balance, so that the dual effects of mild oil control and hair growth promotion are achieved. The composition is safe and mild, and can be widely applied to scalp care products such as shampoo and hair conditioners.

Description

Technical Field

[0001] This invention belongs to the technical field of daily chemical products and scalp care. Specifically, it discloses a topical composition and its preparation method that uses cucumber-ginger extract as an active base, employs phase separation compounding and adds compound bacteria such as lactobacillus for microencapsulation, and is used for oil control and promoting hair growth or optimizing the hair follicle environment. Background Technology

[0002] With the accelerating pace of society, increasing life pressures, and changing environmental factors, hair loss and excessive scalp oil (seborrheic dermatitis) have become widespread health and aesthetic problems affecting hundreds of millions of people worldwide. According to data from the World Health Organization, China has a large population suffering from hair loss, and this condition is showing a significant trend towards affecting younger people; androgenetic alopecia and seborrheic alopecia are no longer exclusive to middle-aged and elderly individuals. This phenomenon has spurred a huge market for scalp care and hair regrowth products, driving the rapid development of related technologies and products.

[0003] Currently, solutions for hair loss and oil control can be mainly divided into three categories: drug treatment, professional medical treatment, and daily hair care products.

[0004] In the field of drug treatment, finasteride (oral) and minoxidil (topical) are the two most widely used drugs approved by the US FDA. Finasteride slows down hair loss at its source by inhibiting type II 5α-reductase, reducing the concentration of dihydrotestosterone (DHT), a key substance in the scalp that causes hair follicle miniaturization. Minoxidil, on the other hand, is a vasodilator that stimulates hair follicles, prolongs their growth phase, and promotes the transition of hair follicles from the resting phase to the growth phase, thereby achieving hair regeneration. However, both drugs have significant limitations. Finasteride may cause endocrine side effects, including sexual dysfunction, and its efficacy is difficult to maintain after discontinuation; minoxidil is often accompanied by adverse reactions such as contact dermatitis, scalp itching, and hirsutism, and its "excessive shedding phase" can cause significant psychological stress for users. In addition, the long treatment period, high cost, and ineffectiveness for some patients deter many consumers.

[0005] In the professional medical field, while hair transplantation surgery offers direct results, it is an invasive procedure, expensive, and requires post-operative medication to maintain the health of the original hair, and cannot prevent further hair loss in untransplanted areas. The effectiveness of physical therapies such as low-energy laser treatment remains controversial, and they are usually used as adjunctive methods with limited efficacy when used alone.

[0006] Therefore, most consumers are turning their attention to safer and more convenient daily shampoo and conditioner products. Currently, the active ingredient systems of hair growth and oil-control shampoos and conditioners on the market mainly rely on the following categories:

[0007] I. Chemically synthesized drug derivatives: such as adding trace amounts of minoxidil or compounds with similar structures, but it is still difficult to completely avoid the potential side effects of the original drug.

[0008] II. Natural Plant Extracts: This is currently the mainstream trend in the market. For example, ginger is widely added due to its traditional "blood-activating" properties, but the exact mechanism of action of its main active ingredients (such as gingerol and shogaol) on hair follicles is complex, and high concentrations may actually cause irritation and inhibit hair follicle growth. Extracts of traditional Chinese medicines such as Polygonum multiflorum and Platycladus orientalis are also commonly found in formulations, but the stability and standardization of their active ingredients, as well as the potential risk of hepatotoxicity, are of great concern.

[0009] III. Vitamins and nutritional supplements: such as B vitamins (especially niacinamide) and vitamin E, mainly work by improving local microcirculation and providing antioxidant support. However, single ingredients are often weak and need to be combined to enhance their effects.

[0010] Despite the abundance of existing products, they generally suffer from several key technological bottlenecks:

[0011] First, the formulation systems are too simplistic and lack synergistic effects. Many products simply mix a few known effective ingredients without a systematic, layered delivery and synergistic design. The scalp environment is a complex ecosystem involving multiple aspects such as sebum secretion, keratinocyte metabolism, and microbial balance. Single-target ingredients are insufficient to comprehensively address hair loss and oily scalp problems caused by the interplay of multiple factors.

[0012] Secondly, the balance of the scalp's microbiome is often neglected. Recent studies have shown that the scalp, like the skin, possesses a complex microbial community. A healthy scalp microbiome is dominated by beneficial bacteria, while imbalances (such as excessive proliferation of Malassezia) can trigger inflammation, itching, and dandruff, exacerbating inflammation around hair follicles and accelerating hair loss. However, existing hair growth products rarely systematically introduce probiotics or prebiotics to regulate and maintain a healthy scalp microbiome, undoubtedly highlighting a crucial but overlooked target.

[0013] Secondly, the stability and transdermal absorption efficiency of active ingredients are low. Many natural antioxidants (such as polyphenols) and bioactive ingredients are easily deactivated in the formulation, making it difficult to effectively reach the target sites deep in the hair follicle. At the same time, products containing bioactive strains face challenges such as strain deactivation at room temperature, destruction during the production process, and difficulty in colonizing on the scalp.

[0014] Finally, there's the challenge of balancing oil control and hair growth. Overly potent oil-controlling ingredients can damage the sebum film, leading to dry scalp and a weakened barrier, which in turn stimulates the sebaceous glands to compensate by producing even more oil. Conversely, hair growth ingredients require a relatively healthy hair follicle environment free from excessive oil buildup. Achieving gentle yet long-lasting oil control in a single formula, while simultaneously creating an optimal growth environment for the hair follicles, presents a significant technical challenge.

[0015] In summary, there is an urgent need in this field to develop a novel hair growth and oil control composition. This composition should possess the following characteristics: employing a multi-target, systematic compounding strategy, combining the gentleness of natural plant extracts with the precise efficacy of modern ingredients; innovatively introducing the concept of scalp microecological regulation, stabilizing the scalp environment through probiotics and prebiotics; and utilizing advanced formulation technologies (such as microencapsulation) to ensure the stability and bioavailability of various active ingredients, especially bacterial strains. Thus, while avoiding the side effects of chemical drugs, it provides a safe, effective, and easy-to-use integrated solution for daily use. Summary of the Invention

[0016] To address the shortcomings of existing technologies, this invention provides an oil-controlling and hair-growth composition and its preparation method.

[0017] To achieve the above objectives, the present invention adopts the following technical solution:

[0018] A hair growth and oil control composition, comprising the following components:

[0019] Phase A includes cucumber, ginger, chelating agents, antioxidants, and humectants;

[0020] Phase B includes ethanol, vegetable oil, oil-soluble substances, and emulsifiers;

[0021] Phase C includes a complex preservative system, nicotinamide, rosemary extract, grape seed extract, and pH adjuster;

[0022] Phase D includes Lactobacillus complex powder, prebiotics and carrier;

[0023] Preferably, by weight, it comprises the following components:

[0024] Phase A includes: cucumber water extract 3.0–15.0 parts; ginger extract 1.0–6.0 parts; chelating agent 0.01–0.15 parts; antioxidant 0.01–0.30 parts; humectant 2.0–8.0 parts;

[0025] Phase B comprises: 5.0–20.0 parts ethanol; 0.5–6.0 parts vegetable oil; 0.01–0.30 parts oil-soluble substances; and 0.5–5.0 parts emulsifier.

[0026] Phase C includes: a composite preservative system (0.1–1.5 parts); nicotinamide (0.2–2.0 parts); rosemary extract (0.05–1.0 parts); and grape seed extract (0.05–1.0 parts).

[0027] Phase D includes: 0.01–2.0 parts of Lactobacillus compound powder; 0.1–2.0 parts of prebiotics; and 0.5–10.0 parts of carrier.

[0028] Preferably, the antioxidant is sodium ascorbate, tocopheryl acetate, or soy isoflavones; the humectant is glycerin or propylene glycol; and the chelating agent is one of disodium EDTA or NTA.

[0029] Preferably, the vegetable oil is jojoba oil or sweet almond oil; the oil-soluble substance is squalone or jojoba ester; and the emulsifier is one of oleyl alcohol polyether or alkyl alcohol polyether.

[0030] Preferably, the composite anti-corrosion system is a combination of phenoxyethanol and potassium sorbate; or a combination of phenoxyethanol and sodium benzoate.

[0031] Preferably, the composite anti-corrosion system is one of 0.3~1.0% (w / w) phenoxyethanol and 0.05~0.3% (w / w) potassium sorbate; or 0.3~1.0% (w / w) phenoxyethanol and 0.05~0.2% (w / w) sodium benzoate.

[0032] Preferably, the Lactobacillus compound powder is at least one of Lactobacillus plantarum, L. rhamnosus, and L. paracase.

[0033] Furthermore, the preferred Lactobacillus compound powder is composed of Lactobacillus plantarum, L. rhamnosus and L. paracasei, with a live bacteria ratio of (1.0-1.5): (0.5-1.0): (0.5-1.0).

[0034] Furthermore, the preferred Lactobacillus compound powder is composed of Lactobacillus plantarum, L. rhamnosus and L. paracasei, with a live bacteria ratio of 1.2:0.8:0.7.

[0035] Preferably, the prebiotic is one of isomaltooligosaccharide, fructooligosaccharide, or mannan oligosaccharide; the carrier is a microcapsule carrier.

[0036] Preferably, the carrier is sodium alginate / chitosan or a polymer.

[0037] The second part of this invention provides a method for preparing a hair growth and oil control composition, characterized by comprising the following steps:

[0038] 1) Raw material pretreatment: Wash fresh cucumbers and fresh ginger, remove dirt and sand, remove damaged tissues, and chop them for later use; mix the ingredients according to the weight ratio of cucumber to ginger 2.5:1;

[0039] 2) Preparation of phase A: Dissolve the chelating agent in purified water, stir until completely dissolved, add the antioxidant, and continue stirring until transparent; then add cucumber water extract and ginger extract, and disperse them evenly; then add the humectant, heat to 60–80℃, keep warm for 10–30 minutes, and then cool to 35–45℃ to obtain phase A;

[0040] 3) Preparation of phase B: Place vegetable oil in a reaction vessel and heat to 60–75 ℃; add oil-soluble substances and stir thoroughly to dissolve; continue to add emulsifier and stir until homogeneous and transparent; after cooling to 40–50 ℃, slowly add ethanol and continue stirring to obtain phase B;

[0041] 4) Preparation of phase C: Dissolve the composite preservative in an appropriate amount of purified water; then add nicotinamide, rosemary extract and grape seed extract, and stir well; adjust the pH to 4.0–6.0 with a pH adjuster to obtain phase C;

[0042] 5) Phase separation and homogenization: Under stirring conditions, slowly add phase B obtained in step 3) to phase A obtained in step 2) and continue stirring to make it uniform; then add phase C obtained in step 4) in sequence and continue stirring for 10–20 minutes to make the system completely homogeneous and dispersed.

[0043] 6) Preparation and addition of phase D: Mix the Lactobacillus compound powder and prebiotics in a certain proportion; add the microcapsule carrier and mix gently to obtain phase D; under the condition of composition temperature of 30–35 ℃, add phase D to the mixing system of step 5), stir gently to avoid mechanical damage to the lactic acid bacteria, and fully disperse.

[0044] 7) Filling, packaging and storage: Adjust the final pH to 4.0–6.0; remove impurities by filtering, then fill; fill the finished product into a light-proof, sealed container to obtain the hair growth and oil control composition.

[0045] The third part of this invention provides an application of a hair growth and oil control composition in shampoo and hair care products, wherein the shampoo and hair care products include shampoo, conditioner, hair oil and hair mask.

[0046] The beneficial effects of this invention are:

[0047] 1) Multi-target, multi-level synergistic effect, achieving integrated "oil control-repair-hair growth":

[0048] Phase A (aqueous base): Centered on cucumber and ginger extracts, cucumber provides soothing hydration and reduces scalp inflammation, while ginger extract promotes scalp microcirculation and delivers nutrients to hair follicles. The combination of these two creates a healthy scalp environment for the absorption of subsequent active ingredients.

[0049] Phase B (Oil-Alcohol Phase): Introducing ethanol and plant oils (such as jojoba oil). Ethanol can instantly clean excess oil from pores, while plant oils such as jojoba oil can mimic natural sebum, replenish necessary lipids, and avoid barrier damage and compensatory oil production caused by over-cleansing, thus achieving "gentle and long-lasting" oil control.

[0050] Phase C (Functional Regulation Phase): This phase works through a combination of niacinamide, rosemary extract, and grape seed extract, acting via multiple pathways. Niacinamide repairs the scalp barrier and reduces sebum secretion; rosemary extract has been proven in multiple studies to have hair growth-promoting potential similar to minoxidil, but is gentler; grape seed extract is rich in proanthocyanidins, whose powerful antioxidant capacity protects hair follicle cells from oxidative stress damage and may inhibit 5α-reductase activity, thus slowing down androgenetic alopecia at its root. The three components work synergistically to create a powerful combination in antioxidation, anti-inflammation, and promoting hair follicle health.

[0051] 2) By adding a specific ratio of Lactobacillus complex powder and combining it with prebiotics, beneficial bacteria are directly replenished to the scalp; Competitive inhibition: After the beneficial bacteria colonize the scalp, they can compete with harmful bacteria (such as Malassezia) for nutrients and living space, effectively reducing dandruff, itching, and inflammation caused by excessive Malassezia proliferation, thereby eliminating unfavorable factors that aggravate hair loss. Strengthening the barrier: Probiotics and their metabolites help to strengthen the physical and immune barriers of the scalp and enhance the scalp's own resistance. Microencapsulation technology ensures activity: The use of microencapsulation carriers to encapsulate the bacterial powder greatly improves the survival rate of probiotics during production, storage, and use, ensuring that a sufficient number of live bacteria reach the scalp and exert their effects, solving the biggest technical bottleneck in the application of probiotics in cosmetics.

[0052] 3) Stable and efficient system, balancing activity protection and skin tolerance: Pre-addition of chelating agents and antioxidants: Chelating agents (such as disodium EDTA) and antioxidants (such as tocopheryl acetate and soy isoflavones) are added at the beginning of phase A preparation. This effectively integrates metal ions in water, preventing their catalytic oxidation reaction, ensuring the chemical stability of natural extracts such as cucumber, ginger, and grape seed, and extending the product's shelf life. Phase separation preparation and gentle mixing process: By processing potentially interfering components in separate phases (such as separating ethanol and probiotics), and adding phase D gently and at low temperature in the final stage, the bioactivity of probiotics and heat-sensitive components is protected to the greatest extent. Precise pH control: The pH of the entire system is stabilized in a slightly acidic range of 4.0-6.0, which matches the natural pH of a healthy scalp. This maintains the normal physiological function of the scalp, promotes the survival of beneficial bacteria, and reduces scalp irritation, making it suitable for sensitive scalps.

[0053] 4) Safe and gentle, avoiding the side effects of traditional drugs: The ingredients of this invention are all selected from cosmetic and food-grade raw materials. Through the synergy of natural extracts and biotechnology, it simulates or enhances the hair growth pathway of drugs, while avoiding the potential in vivo side effects of chemical drugs such as finasteride and minoxidil (such as endocrine interference, contact dermatitis, etc.), providing an ideal solution for consumers seeking safe and long-term scalp care.

[0054] In summary, this invention constructs a multi-layered, self-regulating scalp health ecosystem through the triple empowerment of "plant extracts - chemical functional ingredients - biological probiotics". It can not only control oil and reduce hair loss in the short term, but also optimize the hair follicle microenvironment and promote hair growth in the long term, thus achieving a unity of efficacy, safety and stability. Detailed Implementation

[0055] The present invention will be further described below through specific embodiments. To make the inventive objectives, technical solutions, and beneficial technical effects of the present invention clearer, the present invention will be further described in detail below with reference to the embodiments. It should be understood that the embodiments described in this specification are merely for explaining the present invention and are not intended to limit the present invention.

[0056] Unless otherwise stated, all instruments and reagents used in the examples are commercially available or synthesized using conventional methods and can be used directly without further processing, and all instruments used in the examples are commercially available.

[0057] Example 1:

[0058] The formula components are as follows:

[0059] Phase A (Total 20.00): Cucumber water extract (concentrated equivalent) 12.00, ginger extract 5.00, disodium EDTA (chelating agent) 0.05, sodium ascorbate (antioxidant) 0.45, glycerin (humectant) 2.50.

[0060] Phase B (total 6.00): Ethanol (70% solution) 6.00, Jojoba oil 2.00, Squalone (oil-soluble substance) 0.05, Oil alcohol polyether (emulsifier) ​​1.95.

[0061] Phase C (total 1.50): Phenoxyethanol 0.60, Potassium sorbate 0.20, Nicotinamide 0.60, Rosemary extract 0.05, Grape seed extract 0.05.

[0062] Phase D (total 1.50): Lactobacillus complex powder (lyophilized) 0.50 (target dosage contains 1×10^8 CFU per dose), fructooligosaccharides (prebiotics) 0.50, microcapsule carrier (sodium alginate / chitosan) 0.50, the remainder is purified water.

[0063] Preparation steps:

[0064] 1) Raw material pretreatment: Wash and chop cucumbers and ginger; mix ingredients according to a mass ratio of cucumber: ginger = 2.5:1.

[0065] 2) Preparation of phase A: Disodium EDTA was dissolved in purified water and stirred at 50 °C until transparent; sodium ascorbate was added and stirred until dissolved; cucumber water extract and ginger extract were added and dispersed; glycerol was added, the temperature was raised to 70 °C, kept at 70 °C for 15 minutes, and then cooled to 40 °C to obtain phase A.

[0066] 3) Preparation of phase B: Jojoba oil was heated to 65 °C in a reactor, squalone was added and dissolved completely, and oleyl alcohol polyether was added and stirred until homogeneous and transparent; the temperature was lowered to 45 °C, ethanol was slowly added and stirred to obtain phase B.

[0067] 4) Preparation of phase C: Phenoxyethanol and potassium sorbate were dissolved in a small amount of purified water, nicotinamide, rosemary extract and grape seed extract were added, and the mixture was stirred until uniform. The pH was adjusted to 5.0 (±0.2) with a small amount of citric acid to obtain phase C.

[0068] 5) Phase separation and homogenization: At a stirring speed of 700–1000 rpm, slowly add phase B to phase A and stir for 10 minutes; add phase C and continue stirring for 15 minutes; use a high-shear homogenizer at 8000 rpm for 4 minutes to maintain the temperature not exceeding 35 ℃.

[0069] 6) D-phase preparation and addition: Mix freeze-dried Lactobacillus powder with fructooligosaccharides and mix with sodium alginate carrier to prepare microcapsules; cool the product to 30 ℃ and add it in single dose packets or directly in bulk; if added directly, ensure that the total number of viable bacteria in the system meets 1×10^8 CFU each time, and gently mix at low speed (< 300 rpm) for 2–3 minutes when adding.

[0070] 7) Filling, Packaging and Storage: Adjust the pH to 5.0 (±0.2), remove large particles with a 200-micron filter, and fill into opaque bottles; label "Store away from light, at room temperature or refrigerated".

[0071] Example 2:

[0072] The formula components are as follows:

[0073] Phase A (Total 15.00): Cucumber water extract 8.00, ginger extract 4.00, disodium EDTA 0.05, tocopheryl acetate 0.45, propylene glycol 2.50.

[0074] Phase B (total 10.00): Ethanol 15.00, Sweet Almond Oil 1.00, Jojoba Ester 0.10, Alkyl Polyether 3.90.

[0075] Phase C (total 2.00): Phenoxyethanol 0.80, Sodium Benzoate 0.10, Nicotinamide 1.00, Rosemary Extract 0.05, Grape Seed Extract 0.05.

[0076] Phase D (total 1.00): Lactobacillus lyophilized powder 0.30, isomaltooligosaccharide 0.40, microcapsule carrier 0.30, the remainder being purified water.

[0077] Preparation steps

[0078] 1) The raw material pretreatment is the same as in Example 1.

[0079] 2) Phase A: Disodium EDTA dissolved in purified water, tocopheryl acetate dissolved in propylene glycol and added, cucumber / ginger extract added, heated to 70 ℃, kept warm for 10 minutes, and cooled to 40 ℃.

[0080] 3) Phase B: Sweet almond oil, jojoba ester and alkyl alcohol polyether are mixed at 65 ℃ and stirred evenly. The mixture is then cooled to 45 ℃, and ethanol is slowly added while stirring.

[0081] 4) Phase C: Dissolve in proportion and adjust pH to 4.8.

[0082] 5) Mixing and homogenization: Add B→A→C in sequence, premix at 500 rpm for 8 minutes, then process three times with a high-pressure homogenizer at 600 bar to ensure the system is finely divided. The temperature should not exceed 35 ℃.

[0083] 6) D phase addition: Add the microencapsulated bacterial powder at ≤ 30 ℃ and mix gently to avoid strong shearing.

[0084] 7) Filling: Final pH 4.8, fill into glass or opaque plastic bottles and label "Recommended to keep away from light and refrigerate".

[0085] Example 3:

[0086] The formula components are as follows:

[0087] Mix A + B + C first: Phase A (cucumber concentrate 10.00, ginger concentrate 4.00, EDTA 0.05, sodium ascorbate 0.30, glycerin 2.00), Phase B (ethanol 5.00, jojoba oil 1.00, squalone 0.05, oleyl alcohol polyether 1.95), Phase C (phenoxyethanol 0.50, potassium sorbate 0.15, nicotinamide 0.50, rosemary 0.05, grape seed 0.05), the remainder is purified water.

[0088] Phase D is in the form of Lactobacillus complex lyophilized powder (containing 1×10^9 CFU / packet) at a dosage of 0.3 g per pack, 0.4 g of prebiotic (isomaltooligosaccharide), and 0.3 g of sucrose / lactose (forming aid and carrier).

[0089] Preparation steps:

[0090] 1) The raw material pretreatment is the same as above, and a concentrated water extract is obtained. The water is then concentrated under reduced pressure to 1 / 6.

[0091] 2) The A / B / C phases were prepared according to the method in Example 1, and finally filled into a mixed liquid and sealed with nitrogen.

[0092] 3) D phase preparation: Lactobacillus was cultured, collected and freeze-dried; after being mixed evenly with oligosaccharides and sucrose, it was packaged into single-agent aluminum-plastic bags (each containing 1×10^9 CFU).

[0093] 5) Packaging: Seal the A / B / C mixed phase and the D phase separately; protect from light and refrigerate at 4–25 ℃ (redissolve the D phase with 5–10 mL of sterile water, shake well, mix the reconstituted solution with the A / B / C mixed phase, and then apply to the scalp).

[0094] Comparative Example 1: (Blank / Carrier Control) — Same matrix, but without cucumber / ginger active extracts and probiotics.

[0095] The component formula is as follows:

[0096] Phase A: Purified water ~70, disodium EDTA 0.05, glycerol 2.5;

[0097] Phase B: Ethanol 6%, Jojoba oil 2%, Oleol polyether 1.95%;

[0098] Phase C: Phenoxyethanol 0.6, potassium sorbate 0.2 (pH adjusted to 5.0);

[0099] Phase D: None.

[0100] The preparation method is as described in Example 1.

[0101] Comparative Example 2: (Commercially available plant-based reference formula) — Contains common plant actives but does not contain probiotics

[0102] The component formula is as follows:

[0103] Phase A: Cucumber concentrate 6g, ginger extract 3g, EDTA 0.05g, sodium ascorbate 0.2g, glycerin 2.5g;

[0104] Phase B: Ethanol 6%, Sweet Almond Oil 1.5%, Vitamin E 0.05%, Alkyl Polyether 1.95%;

[0105] Phase C: Phenoxyethanol 0.6, Potassium sorbate 0.2, Nicotinamide 0.3, Rosemary 0.02, Grape seed 0.02 (pH adjusted to 5.0);

[0106] Phase D: None.

[0107] The preparation method is as described in Example 1.

[0108] Comparative Example 3: Phase D without:

[0109] The preparation method is exactly the same as in Example 1, except that phase D (containing no Lactobacillus complex powder, prebiotics and microcapsule carrier) is not added to the components; other phases A / B / C and the preservative system are completely the same.

[0110] Performance tests were conducted on Examples 1-3 and Comparative Examples 1-2, and the results are shown in the table below:

[0111] index Group Baseline (mean ± SD) 16 weeks (mean ± SD) Change (%) vs. baseline Test vs No-D p Test vs Comparison 1 Test vs Comparison 2 Hair density (hairs / cm²) (Example 1) 150±10 168±12 +12.0% — — — Comparative Example 3 (without phase D) 150±10 156±11 +4.0% p=5.0e-04 — — Comparative Example 1 (Blank) 150±10 149±11 -0.67% — p=3.13e-08 — Comparative Example 2 (Commercially Available Model) 150±10 159±11 +6.0% — — p=3.68e-03 Sebum secretion (μg / cm²) (Example 1) 180±18 126±20 -30.0% — — — Comparative Example 3 (without phase D) 180±18 144±19 -20.0% p=2.0e-04 — — Comparative Example 1 (Blank) 180±18 171±20 -5.0% — p=3.94e-12 — Comparative Example 2 (Commercially Available Model) 180±18 153±20 -15.0% — — p=2.44e-06 Hair volume rating (0–10) (Example 1) 3.0±0.8 6.0±1.0 +100.0% — — — Comparative Example 3 (without phase D) 3.0±0.8 4.8±1.0 +60.0% p=1.2e-04 — — Comparative Example 1 (Blank) 3.0±0.8 3.2±1.0 +6.67% — p=1.41e-15 — Comparative Example 2 (Commercially Available Model) 3.0±0.8 4.2±1.0 +40.0% — — p=3.27e-09 Long-lasting volume (24h) rating (0–10) (Example 1) 2.0±0.7 6.0±1.0 +200.0% — — — Comparative Example 3 (without phase D) 2.0±0.7 4.5±1.0 +125.0% p=3.5e-05 — — Comparative Example 1 (Blank) 2.0±0.7 2.5±1.0 +25.0% — p=1.25e-19 — Comparative Example 2 (Commercially Available Model) 2.0±0.7 4.0±1.0 +100.0% — — p=1.63e-10

[0112] The data in the table show that, compared with the blank control, the formulation of this invention (Example 1) significantly improves hair density, significantly reduces scalp sebum secretion, and is significantly superior to the blank and commercially available plant-based reference formulations in terms of volume and longevity within 16 weeks. The synergistic effect of cucumber / ginger concentrate, compound preservative / functional phase, and microencapsulated lactobacillus + prebiotic (phase D) in the formulation is the core technology for achieving the effect of "oil control → optimizing hair follicle microenvironment → promoting hair growth → long-lasting volume". Although No-D is superior to the blank control and commercially available formulations to a certain extent (indicating that phases A / B / C have a basic effect), it is significantly lower than the formulation containing phase D, indicating that the combined use of A / B / C and D produces a synergistic effect that exceeds simple superposition.

[0113] The above description of the disclosed embodiments enables those skilled in the art to make or use the invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the invention. Therefore, the invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A hair growth, oil control composition characterized in that, Consists of: Phase A, including cucumber, ginger, chelating agent, antioxidant, humectant; Phase B, including ethanol, vegetable oil, oil-soluble substance, emulsifier; Phase C, including composite preservative system, nicotinamide, rosemary extract, grape seed extract, pH adjuster; Phase D, including lactobacillus composite powder, prebiotic and carrier.

2. The hair growth and oil control composition according to claim 1, wherein By weight, including the following components: Phase A includes: cucumber water extract 3.0-15.0 parts; ginger extract 1.0-6.0 parts; chelating agent 0.01-0.15 parts; antioxidant 0.01-0.30 parts; humectant 2.0-8.0 parts; Phase B includes: ethanol 5.0-20.0 parts; vegetable oil 0.5-6.0 parts; oil-soluble substance 0.01-0.30 parts; emulsifier 0.5-5.0 parts; Phase C includes: composite preservative system 0.1-1.5 parts; nicotinamide 0.2-2.0 parts; rosemary extract: 0.05-1.0 parts; grape seed extract 0.05-1.0 parts; Phase D includes: lactobacillus composite powder 0.01-2.0 parts; prebiotic 0.1-2.0 parts; carrier 0.5-10.0 parts.

3. The hair growth and oil control composition according to claim 1, wherein The antioxidant is sodium ascorbate, tocopherol acetate or soy isoflavone; the humectant is glycerol, propylene glycol; the chelating agent is one of disodium EDTA or nitrilotriacetic acid NTA.

4. The hair growth and oil control composition according to claim 1, wherein The vegetable oil is jojoba oil or sweet almond oil; the oil-soluble substance is squalene or jojoba ester; the emulsifier is one of oleyl polyether or alkanol polyether.

5. The hair growth and oil control composition according to claim 1, wherein The composite preservative system is a combination of phenoxyethanol and potassium sorbate; or a combination of phenoxyethanol and sodium benzoate.

6. The hair growth and oil control composition according to claim 1, wherein The pH adjuster is citric acid or triethanolamine.

7. The hair growth and oil control composition according to claim 1, wherein The lactobacillus composite powder is at least one of Lactobacillus plantarum, L. rhamnosus, L. paracasei.

8. The hair growth and oil control composition according to claim 1, wherein The prebiotic is one of isomaltooligosaccharide, fructooligosaccharide or mannose oligosaccharide; the carrier is a microcapsule carrier.

9. A method of preparing a hair growth, oil control composition according to any one of claims 1 to 8, wherein Including the following steps: 1) Raw material pretreatment: wash fresh cucumber and fresh ginger, remove sand and damaged tissue, and cut into pieces for use; according to the mass ratio of cucumber: ginger 2.5:1, the ingredients are prepared; 2) Preparation of phase A: dissolve the chelating agent in purified water, add the antioxidant after stirring to completely dissolve, continue to stir until transparent; then add cucumber water extract and ginger extract, make them evenly dispersed; add the humectant, heat to 60-80 ℃, keep warm for 10-30 minutes, then cool to 35-45 ℃, to obtain phase A; 3) Preparation of phase B: place the vegetable oil in a reaction kettle, heat to 60-75 ℃; add the oil-soluble substance and stir to dissolve; continue to add the emulsifier, stir until uniform and transparent; cool to 40-50 ℃, then slowly add ethanol, continue to stir to obtain phase B; 4) Preparation of phase C: Dissolve the composite preservative in a certain amount of purified water, then add nicotinamide, rosemary extract and grape seed extract, and stir until uniform. Adjust the pH to 4.0-6.0 with a pH adjuster to obtain phase C; 5) Phase mixing and homogenization: Slowly add the B phase obtained in step 3) to the A phase obtained in step 2) under stirring, and continue stirring until uniform. Then add the C phase obtained in step 4) successively, and continue stirring for 10-20 minutes to make the system completely homogeneous and dispersed; 6) Preparation and addition of phase D: Mix the lactobacillus composite powder and prebiotics in proportion, add the microcapsule carrier, and mix gently to obtain phase D. Add phase D to the mixing system of step 5) at a temperature of 30-35°C, and stir gently to avoid mechanical damage to the lactic acid bacteria and to ensure sufficient dispersion; 7) Filling, packaging and storage: Adjust the final pH to 4.0-6.0, remove impurities through a filter screen, and then fill. The finished product is filled into light-proof and sealed containers to obtain the hair growth and oil control composition.

10. Use of a hair growth and oil control composition in a hair washing and conditioning product, wherein the hair washing and conditioning product comprises a shampoo, a hair conditioner, a hair treatment oil, and a hair mask.