Eutectic surfactant and preparation method thereof

Abstract

The invention relates to a eutectic surfactant and a preparation method thereof, and belongs to the technical field of eutectic. The preparation method of the eutectic surfactant comprises the following steps: dissolving N-acyl amino acid salt in deionized water, then adding N-acyl glycine salt and sodium lauryl phosphate for blending, carrying out intermittent ultrasonic treatment, finally dropwise adding ethanol, mixing and crystallizing. The eutectic surfactant has a good foaming effect, can obtain better foaming performance under the same components, proportion and dosage compared with the non-formed eutectic surfactant, can correspondingly reduce the usage amount of the surfactant when being applied to the washing and care cosmetics, and has very strong practicability.

Description

Technical Field

[0001] This invention belongs to the field of eutectic technology, specifically relating to a eutectic surfactant and its preparation method. Background Technology

[0002] Eutectic technology is a technique that precisely controls the proportion of two or more components to form a stable eutectic at the molecular level. This process can change the crystal form, melting point, and dissolution behavior of a substance, thereby significantly improving its physicochemical properties. The formation of eutectic mainly relies on the interaction of nonionic and non-covalent bonds and does not involve the formation of chemical bonds.

[0003] In the cosmetics industry, cocrystallization technology is widely used to improve the solubility and stability of active ingredients, allowing poorly soluble or easily oxidized components to exist in a milder and more stable form, while achieving a certain solubilizing effect, thereby improving the texture and bioavailability of the formulation. With the increasing popularity and attention to the concept of "synergistic effect," cocrystallization technology has gradually been extended to surfactant systems. As a key component of cleansing and care cosmetics, the foaming performance of surfactants directly determines the quality of the product. Traditional formulations and processes often require the compounding of multiple surfactants to improve performance, but the overall amount used is still relatively large. If cocrystallization technology can be used to regulate the molecular interactions between surfactants, it is expected to achieve better foaming effects at lower concentrations and enhance the synergistic effect between surfactants. However, current research on the foaming of surfactant cocrystallization systems is still relatively scarce and needs further exploration. Summary of the Invention

[0004] The purpose of this invention is to provide a eutectic surfactant and its preparation method to solve the problems existing in the background art.

[0005] To achieve the above objectives, the present invention provides the following solution: In a first aspect, the present invention provides a method for preparing a eutectic surfactant, the method comprising the following steps: Add deionized water to the N-acyl amino acid salt, heat and keep warm, stir and mix once, add N-acyl glycinate salt and sodium lauryl phosphate, stir and mix a second time, sonicate intermittently, add ethanol dropwise while stirring, after the addition is complete, stir and mix a third time, filter, discard the filtrate, dry, and the preparation is complete.

[0006] In a preferred embodiment of the present invention, the N-acyl amino acid salt is at least one selected from capryloyl amino acid salt, decanoyl amino acid salt, lauroyl amino acid salt, myristoyl amino acid salt, palmitoyl amino acid salt, and stearoyl amino acid salt; the capryloyl amino acid salt is at least one selected from capryloyl glutamate, capryloyl aminopropionate, capryloyl β-alanine salt, capryloyl methyl taurate, and capryloyl aspartate salt; the decanoyl amino acid salt is at least one selected from decanoyl glutamate, decanoyl aminopropionate, decanoyl β-alanine salt, decanoyl methyl taurate, and decanoyl aspartate salt; the lauroyl amino acid salt is lauroyl glutamate, lauroyl aminopropionate, lauroyl β-alanine salt, and lauroyl β-alanine salt. At least one of β-alanine salt, lauroyl methyl taurate, and lauroyl aspartate salt; the myristoyl amino acid salt is at least one of myristoyl glutamate, myristoyl aminopropionate, myristoyl β-alanine salt, myristoyl methyl taurate, and myristoyl aspartate salt; the palmitoyl amino acid salt is at least one of palmitoyl glutamate, palmitoyl aminopropionate, palmitoyl β-alanine salt, palmitoyl methyl taurate, and palmitoyl aspartate salt; the stearoyl amino acid salt is at least one of stearoyl glutamate, stearoyl aminopropionate, stearoyl β-alanine salt, stearoyl methyl taurate, and stearoyl aspartate salt.

[0007] As a preferred embodiment of the present invention, the N-acylglycine salt is at least one selected from octanoylglycine salt, decanoylglycine salt, lauroylglycine salt, myristoylglycine salt, palmitoylglycine salt, and stearoylglycine salt.

[0008] As a preferred embodiment of the present invention, the mass ratio of the N-acyl amino acid salt, the deionized water, the N-acyl glycine salt, the sodium lauryl phosphate, and the ethanol is 1:15-20:1-4:0.2-0.5:170-220.

[0009] As a preferred embodiment of the present invention, the heating refers to heating to 50-80°C at a heating rate of 2-4°C / min.

[0010] As a preferred embodiment of the present invention, the "one-time mixing" refers to mixing for 10-30 minutes.

[0011] As a preferred embodiment of the present invention, the secondary stirring and mixing refers to stirring for 20-45 minutes.

[0012] As a preferred embodiment of the present invention, the intermittent ultrasound operation is to first perform ultrasound treatment for 2-4 minutes, then pause for 30-45 seconds, and repeat alternately; the total time of the intermittent ultrasound is 25-40 minutes; and the amplitude of the ultrasound treatment is 50-75%.

[0013] As a preferred embodiment of the present invention, the dropping rate is 0.05-0.5% of the volume of ethanol added per second.

[0014] As a preferred embodiment of the present invention, the three-stage mixing refers to mixing for 2-2.5 hours.

[0015] As a preferred embodiment of the present invention, the drying temperature is 40-65℃.

[0016] As a preferred embodiment of the present invention, the drying time is 10-16 hours.

[0017] Secondly, the present invention provides a eutectic surfactant prepared by the preparation method described above.

[0018] The beneficial effects of this invention are: 1. This invention prepares a eutectic surfactant by forming a eutectic of N-acyl amino acid salt, N-acyl glycine salt and sodium lauryl phosphate, which effectively enhances the synergistic effect among them and greatly improves the foaming performance.

[0019] 2. The eutectic surfactant prepared by this invention is mainly composed of amino acid-type surfactants and supplemented by phosphate ester-type surfactants. Both types of components are commonly used surfactants in daily life and have the advantages of being mild and low in irritation, highly compatible, and environmentally friendly.

[0020] 3. The eutectic surfactant prepared by this invention is formed through weak interactions such as van der Waals forces, hydrogen bonds, and dipoles, without involving the formation of new substances, thus ensuring safety and usability. At the same time, this invention couples intermittent ultrasonic technology into the preparation of the eutectic surfactant, introducing acoustic cavitation effect to promote intermolecular collisions and interactions. The intermittent design can balance the relationship between kinetics and thermal effects, forming a better arrangement and stacking structure, and more significantly improving foaming performance.

[0021] 4. The eutectic surfactant prepared by this invention has good foaming effect. Compared with the non-eutectic surfactant, it can achieve better foaming performance with the same ingredients, ratio and dosage. When applied to washing and care cosmetics, the amount of surfactant used can be reduced accordingly, which is very practical. Detailed Implementation

[0022] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0023] Example 1 A method for preparing a eutectic surfactant, the method comprising the following steps: Deionized water was added to the N-acyl amino acid salt, the mixture was heated and kept at that temperature, and stirred and mixed once. Then, N-acylglycine salt and sodium lauryl phosphate were added, and the mixture was stirred and mixed a second time. The mixture was then sonicated intermittently, and ethanol was added dropwise while stirring. After the addition was complete, the mixture was stirred and mixed a third time, filtered, the filtrate was discarded, and the solution was dried to obtain the final product. The N-acyl amino acid salt was sodium lauroyl β-alanine; the N-acylglycine salt was potassium lauroylglycine; and the mass ratio of the N-acyl amino acid salt, the deionized water, the N-acylglycine salt, the sodium lauryl phosphate, and the ethanol was 1:15:1:0.2:17. 0; The heating refers to heating to 50°C at a heating rate of 2°C / min; The first stirring and mixing refers to stirring for 10 minutes; The second stirring and mixing refers to stirring for 20 minutes; The intermittent ultrasound operation is to first sonicate for 2 minutes, then pause for 30 seconds, and repeat alternately; The total time of the intermittent ultrasound is 25 minutes; The amplitude of the ultrasound treatment is 50%; The dropping rate is 0.05% of the volume of ethanol added per second; The third stirring and mixing refers to stirring for 2 hours; The drying temperature is 40°C; The drying time is 10 hours.

[0024] A eutectic surfactant prepared by the preparation method described above.

[0025] Example 2 A method for preparing a eutectic surfactant, the method comprising the following steps: Deionized water was added to the N-acyl amino acid salt, the mixture was heated and kept at that temperature, and stirred and mixed once. Then, N-acylglycine salt and sodium lauryl phosphate were added, and the mixture was stirred and mixed a second time. The mixture was then sonicated intermittently, and ethanol was added dropwise while stirring. After the addition was complete, the mixture was stirred and mixed a third time, filtered, the filtrate was discarded, and the solution was dried to obtain the final product. The N-acyl amino acid salt was sodium lauroyl β-alanine; the N-acylglycine salt was potassium lauroylglycine; and the mass ratio of the N-acyl amino acid salt, the deionized water, the N-acylglycine salt, the sodium lauryl phosphate, and the ethanol was 1:17:3:0.4:200. The heating refers to heating to 70°C at a rate of 3°C / min; the first stirring and mixing refers to stirring for 20 minutes; the second stirring and mixing refers to stirring for 30 minutes; the intermittent ultrasound operation involves first ultrasound treatment for 3 minutes, then pausing for 40 seconds, and repeating alternately; the total time of the intermittent ultrasound is 30 minutes; the amplitude of the ultrasound treatment is 70%; the dropping rate is 0.1% of the volume of ethanol added per second; the third stirring and mixing refers to stirring for 2.3 hours; the drying temperature is 60°C; and the drying time is 14 hours.

[0026] A eutectic surfactant prepared by the preparation method described above.

[0027] Example 3 A method for preparing a eutectic surfactant, the method comprising the following steps: Deionized water was added to the N-acyl amino acid salt, the mixture was heated and kept at that temperature, and stirred and mixed once. Then, N-acylglycine salt and sodium lauryl phosphate were added, and the mixture was stirred and mixed a second time. The mixture was then sonicated intermittently, and ethanol was added dropwise while stirring. After the addition was complete, the mixture was stirred and mixed a third time, filtered, the filtrate was discarded, and the solution was dried to obtain the final product. The N-acyl amino acid salt was sodium lauroyl β-alanine; the N-acylglycine salt was potassium lauroylglycine; and the mass ratio of the N-acyl amino acid salt, the deionized water, the N-acylglycine salt, the sodium lauryl phosphate, and the ethanol was 1:20:4:0.5:220. The heating refers to heating to 80°C at a rate of 4°C / min; the first stirring and mixing refers to stirring for 30 minutes; the second stirring and mixing refers to stirring for 45 minutes; the intermittent ultrasound operation involves first ultrasound treatment for 4 minutes, then pausing for 45 seconds, and repeating alternately; the total time of the intermittent ultrasound is 40 minutes; the amplitude of the ultrasound treatment is 75%; the dropping rate is 0.5% of the volume of ethanol added per second; the third stirring and mixing refers to stirring for 2.5 hours; the drying temperature is 65°C; and the drying time is 16 hours.

[0028] A eutectic surfactant prepared by the preparation method described above.

[0029] Comparative Example 1 The difference from Example 2 is that, while maintaining the same mass, sodium lauroyl β-alanine was completely replaced with potassium lauroyl glycinate and sodium lauryl phosphate (mass ratio 3:0.4).

[0030] Comparative Example 2 The difference from Example 2 is that, while maintaining the same mass, all of the potassium lauroyl glycinate was replaced with sodium lauroyl β-alanine and sodium lauryl phosphate (mass ratio 1:0.4).

[0031] Comparative Example 3 The difference from Example 2 is that, while maintaining the same mass, sodium lauryl phosphate is completely replaced with sodium lauroyl β-alanine and potassium lauroyl glycinate (mass ratio 1:3).

[0032] Comparative Example 4 The difference from Example 2 is that the intermittent ultrasound was replaced with stirring for 30 minutes.

[0033] Comparative Example 5 The difference from Example 2 is that intermittent ultrasound is replaced with ultrasound, wherein the ultrasound operation is to treat with ultrasound at 70% amplitude for 30 minutes.

[0034] Test Example 1 Foaming performance test: Take 5g of the eutectic surfactant prepared in Examples 1-3 and Comparative Examples 1-5, 5g of sodium lauroyl β-alanine, potassium lauroyl glycinate, and sodium lauryl phosphate (control group) in a mass ratio of 1:3:0.4, and place them in 80g of deionized water. Mix them in a mixer of the same model (150rpm, 1min). Then, pour them into 1L graduated cylinders of the same size and observe the foam reading (including the volume of the liquid itself). Repeat the above operation 3 times, calculate the average value, and round it to the nearest integer.

[0035] Table 1. Experimental results of foaming performance test As can be seen from the experimental results of the foaming performance test in Table 1 above, the present invention produces a eutectic surfactant, which effectively enhances the synergistic effect between the surfactants and greatly improves the foaming performance. When applied to washing and care cosmetics, the amount of surfactant used can be reduced accordingly, making it highly practical.

[0036] In the description of this specification, the references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0037] The above description is merely an example and illustration of the concept of the present invention. Those skilled in the art can make various modifications or additions to the specific embodiments described or use similar methods to replace them, as long as they do not deviate from the concept of the invention or exceed the scope defined in the claims, they should all fall within the protection scope of the present invention.

Claims

1. A method for preparing a eutectic surfactant, characterized in that: The preparation method includes the following steps: Add deionized water to the N-acyl amino acid salt, heat and keep warm, stir and mix once, add N-acyl glycinate salt and sodium lauryl phosphate, stir and mix a second time, sonicate intermittently, add ethanol dropwise while stirring, after the addition is complete, stir and mix a third time, filter, discard the filtrate, dry, and the preparation is complete.

2. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The N-acyl amino acid salt is at least one selected from the following: capryloyl amino acid salt, decanoyl amino acid salt, lauroyl amino acid salt, myristoyl amino acid salt, palmitoyl amino acid salt, and stearoyl amino acid salt; the capryloyl amino acid salt is at least one selected from the following: capryloyl glutamate, capryloyl aminopropionate, capryloyl β-alanine salt, capryloyl methyl taurate, and capryloyl aspartate salt; the decanoyl amino acid salt is at least one selected from the following: decanoyl glutamate, decanoyl aminopropionate, decanoyl β-alanine salt, decanoyl methyl taurate, and decanoyl aspartate salt; the lauroyl amino acid salt is at least one selected from the following: lauroyl glutamate, lauroyl aminopropionate, lauroyl β-alanine salt, lauroyl... At least one of acylmethyl taurate and lauroyl aspartate; the myristoyl amino acid salt is at least one of myristoyl glutamate, myristoyl aminopropionate, myristoyl β-alanine, myristoyl methyl taurate, and myristoyl aspartate; the palmitoyl amino acid salt is at least one of palmitoyl glutamate, palmitoyl aminopropionate, palmitoyl β-alanine, palmitoyl methyl taurate, and palmitoyl aspartate; the stearoyl amino acid salt is at least one of stearoyl glutamate, stearoyl aminopropionate, stearoyl β-alanine, stearoyl methyl taurate, and stearoyl aspartate.

3. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The N-acylglycine salt is at least one of capryloylglycine salt, decylglycine salt, lauroylglycine salt, myristoylglycine salt, palmitoylglycine salt, and stearoylglycine salt.

4. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The mass ratio of the N-acyl amino acid salt, the deionized water, the N-acyl glycine salt, the sodium lauryl phosphate, and the ethanol is 1:15-20:1-4:0.2-0.5:170-220.

5. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The heating refers to heating to 50-80℃ at a heating rate of 2-4℃ / min.

6. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The term "one-time mixing" refers to mixing for 10-30 minutes.

7. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The secondary mixing refers to mixing for 20-45 minutes.

8. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The intermittent ultrasound operation involves first performing ultrasound treatment for 2-4 minutes, then pausing for 30-45 seconds, and repeating this process alternately; the total duration of the intermittent ultrasound is 25-40 minutes; and the amplitude of the ultrasound treatment is 50-75%.

9. The method for preparing a eutectic surfactant according to claim 1, characterized in that: The three-stage mixing refers to mixing for 2-2.5 hours.

10. A eutectic surfactant prepared by the preparation method according to any one of claims 1-9.

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