Composition for inhibiting bacteria, removing dandruff, relieving itching and controlling oil as well as preparation method and application of composition

Abstract

The invention belongs to the technical field of preparation of wash supplies, and particularly relates to a composition for inhibiting bacteria, removing dandruff, relieving itching and controlling oil as well as a preparation method and application thereof. Through subcritical extraction of purslane, aloe barbadensis and radix sophorae flavescentis, decomposition of active ingredients such as polyphenol, essential oil and vitamins is avoided, the active ingredients are high in activity, the safety is remarkably improved, a specific subcritical solvent is used, and solvent impurities and chemical pollutants are completely eradicated; the golden chamomile, the pelargonium graveolens and the field mint are extracted by using an alcoholic solution, so that efficient extraction, deep purification and impurity removal are realized, and efficient separation of pesticide residues, heavy metals and potential sensitizing proteins in plant extracts and removal of plant pigments and unpleasant odor substances are facilitated. Therefore, the technical scheme provided by the invention can be used for preparing products for inhibiting bacteria, removing dandruff, relieving itching and controlling oil, and is green and safe.

Description

Technical Field

[0001] This invention belongs to the field of preparation of personal care products, specifically relating to an antibacterial, dandruff-removing, itch-relieving, and oil-controlling composition, its preparation method, and its application. Background Technology

[0002] Scalp and dandruff problems have always been a concern, not only related to appearance but also serving as a barometer of internal health, profoundly impacting mental well-being and the quality of social life. For example, dandruff is a mild manifestation of seborrheic dermatitis, which can lead to severe scalp redness, swelling, and intense itching in severe cases. It may be associated with psoriasis, eczema, or fungal infections. Persistent itching can lead to scratching, increasing the risk of secondary infections. Therefore, scalp problems can cause anxiety, social avoidance, and even affect career development. Persistent itching and discomfort can distract attention and reduce work and study efficiency.

[0003] Shampoo and conditioner are everyday products that can quickly solve the aforementioned dandruff and scalp problems. Examples include ketoconazole and minoxidil. However, long-term use may lead to dry scalp and persistent irritation, making the effects less than ideal. Therefore, shampoos and conditioners with natural plant-based ingredients are highly sought after. For instance, Chinese patent CN 119488469 A describes an anti-hair loss and dandruff composition and its preparation method, which involves specific enzymatic hydrolysis and fermentation of plant raw materials. The resulting antioxidants prevent the oxidation of unsaturated fatty acids and antioxidants in plant extracts, extending the product's shelf life, decomposing macromolecules, making the composition more refined, and improving the user experience. However, this process requires specific enzymes, which are expensive, and the preparation process is relatively specialized. Therefore, providing a more convenient preparation method would not only broaden the methods for preparing plant raw materials but also accelerate the development of shampoos and conditioners, a problem urgently needing to be solved in this field. Summary of the Invention

[0004] The purpose of this invention is to provide a composition for antibacterial, anti-dandruff, anti-itch and oil control, as well as its preparation method and application. The preparation method is simple and the ingredients have high activity.

[0005] This invention provides a method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: C12-13 alcohol lactate, piroctone ketone ethanolamine salt, menthol lactate, zinc PCA, panthenol, β-glucan, purslane extract, golden chamomile extract, geranium extract, field pepper extract, aloe vera extract and sophora flavescens extract are mixed evenly to obtain an antibacterial, anti-dandruff, antipruritic and oil-controlling composition. The preparation method of the purslane extract, aloe vera extract or sophora flavescens extract is as follows: the plant sample is dried and subjected to subcritical extraction to obtain the plant extract; The preparation method of the golden chamomile extract, geranium extract or field peppermint extract is as follows: the plant sample is mixed with black rice water, homogenized, vacuum concentrated and centrifuged to obtain supernatant 1; an alcohol solution is added to supernatant 1, and the mixture is allowed to stand and centrifuged to obtain supernatant 2; supernatant 2 is concentrated and dried to obtain the plant extract. The alcohol solution includes: methanol solution and ethanol solution.

[0006] Preferably, the composition comprises the following raw materials in parts by weight: C12-13 alcohol lactate 0.2-2.0 parts, piroctone olamine salt 0.05-1.0 parts, menthol lactate 0.1-1.0 parts, zinc PCA 0.01-1.0 parts, panthenol 0.005-2.0 parts, β-glucan 0.001-1.0 parts, purslane extract 0.001-1.0 parts, golden chamomile extract 0.0005-1.0 parts, geranium extract 0.0005-1.0 parts, peppermint extract 0.0001-1.0 parts, aloe vera extract 0.0001-1.0 parts, and sophora flavescens extract 0.0001-1.0 parts.

[0007] Preferably, during subcritical extraction, the mass-to-volume ratio of plant sample to extractant is 1g:12-15mL; and the water content of the plant sample is 15%-20%.

[0008] Preferably, the extractant is isobutane.

[0009] Preferably, the subcritical extraction temperature is 45-60℃, the pressure is 2-5MPa, and the time is 3-4h.

[0010] Preferably, during homogenization, the mass ratio of plant sample to black rice water is 1:1-2; The method for preparing black rice water is as follows: black rice and water are mixed and soaked in a mass ratio of 1:10, then filtered to obtain black rice water.

[0011] Preferably, the volume is vacuum concentrated to 1 / 3-2 / 3 of the original volume at 60-65℃.

[0012] Preferably, when standing, the volume ratio of supernatant 1 to alcohol solution is 1:6-8; In the alcohol solution, the volume ratio of methanol solution to ethanol solution is 1:1-2; The volume concentration of the ethanol solution is 45%-55%; the volume concentration of the methanol solution is 45%-55%.

[0013] The present invention provides an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition obtained by the preparation method described in the above technical solution.

[0014] The present invention provides the application of the composition described in the above technical solution in the preparation of one or more products with antibacterial, anti-dandruff, antipruritic and oil-controlling properties.

[0015] Beneficial effects: This invention provides a method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: mixing C12-13 alcohol lactate, piroctone ketone ethanolamine salt, menthol lactate, zinc PCA, panthenol, β-glucan, purslane extract, golden chamomile extract, geranium extract, field pepper extract, aloe vera extract, and sophora flavescens extract evenly to obtain an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition; the preparation method of the purslane extract, aloe vera extract, or sophora flavescens extract is as follows: drying the plant sample and performing subcritical extraction to obtain the plant extract; the preparation method of the golden chamomile extract, geranium extract, or field pepper extract is as follows: mixing the plant sample with black rice water, homogenizing, vacuum concentrating, and centrifuging to obtain supernatant 1; adding an alcohol solution to supernatant 1, allowing it to stand, centrifuging to obtain supernatant 2, concentrating and drying supernatant 2 to obtain the plant extract; the alcohol solution includes: methanol solution and ethanol solution.

[0016] This invention utilizes subcritical extraction to avoid the decomposition of active ingredients such as polyphenols, essential oils, and vitamins, resulting in high ingredient activity and significantly improved safety. The use of a specific subcritical solvent eliminates solvent impurities and chemical contaminants. The extraction of plants using an ethanol solution not only achieves deep purification and removes impurities but also facilitates the efficient separation of pesticide residues, heavy metals, and potentially allergenic proteins from the plant extract, as well as the removal of plant pigments and unpleasant odor substances. Therefore, the preparation method of this invention achieves the goal of "precise extraction + deep purification," and can be used to prepare products for antibacterial, anti-dandruff, anti-itch, and oil-controlling purposes. It is green, safe, and the preparation method is simple. Detailed Implementation

[0017] In this invention, unless otherwise specified, the raw materials, equipment and methods used are all conventional selections.

[0018] To further illustrate the present invention, the solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0019] In the embodiments and comparative examples of the present invention, the method for preparing black rice water is as follows: black rice and water are mixed at a mass ratio of 1:10, soaked at 30°C for 4 hours, and then filtered to obtain black rice water.

[0020] Example 1 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: Purslane ( Portulaca oleracea L.) was washed and dried to obtain dried purslane (moisture content of 20%); using isobutane as the extractant, purslane and extractant were subjected to subcritical extraction at a mass-volume ratio of 1g:12mL (temperature of 45℃, pressure of 5MPa, time of 4h) to obtain purslane extract. Aloe vera ( Aloe barbadensis Miller The aloe vera was washed and dried to obtain dried aloe vera (moisture content of 20%). Using isobutane as the extractant, aloe vera and extractant were subjected to subcritical extraction at a mass-volume ratio of 1g:12mL (temperature 45℃, pressure 5MPa, time 4h) to obtain aloe vera extract. Sophora flavescens ( Sophora flavescens Aiton The roots of Sophora flavescens were washed and dried to obtain dried Sophora flavescens (moisture content of 20%). Using isobutane as the extractant, subcritical extraction was performed at a mass-volume ratio of 1g:12mL (temperature 45℃, pressure 5MPa, time 4h) to obtain Sophora flavescens extract. Golden chamomile ( Chrysanthellum indicum The mixture of chamomile and black rice water at a mass ratio of 1:2 was pulverized to obtain a golden chamomile slurry (wherein the particle size of the golden chamomile in the slurry is ≤0.1cm). The slurry was then vacuum concentrated to 2 / 3 of its original volume at 60℃, and centrifuged to obtain the supernatant. The supernatant was then mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of the ethanol solution was 45% and the volume concentration of the methanol solution was 45%) at a volume ratio of 1:8, and allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and the supernatant was concentrated and dried until the weight of the substance no longer changed, thus obtaining the golden chamomile extract. Geranium ( Pelargonium graveolens The stems of geraniums were mixed with black rice water at a mass ratio of 1:2 and pulverized to obtain geranium slurry (wherein the particle size of geraniums in the slurry is ≤0.1cm). The slurry was then vacuum concentrated to 2 / 3 of its original volume at 60℃, and centrifuged to obtain the supernatant. The supernatant was mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of ethanol solution was 45% and the volume concentration of methanol solution was 45%) at a volume ratio of 1:8, and allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and the supernatant was concentrated and dried until the weight of the substance no longer changed, thus obtaining geranium extract. field mint ( Mentha arvensis The leaves of *L.* and black rice water were mixed and pulverized at a mass ratio of 1:2 to obtain a field mint slurry (wherein the particle size of the field mint in the slurry is ≤0.1cm). The slurry was then vacuum concentrated to 2 / 3 of its original volume at 60℃, and centrifuged to obtain the supernatant. The supernatant was mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of the ethanol solution was 45% and the volume concentration of the methanol solution was 45%) at a volume ratio of 1:8, and allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and the supernatant was concentrated and dried until the weight of the substance no longer changed to obtain the field mint extract. 0.20 parts of C12-13 alcohol lactate, 1.0 part of piroctone olamine salt, 0.1 part of menthol lactate, 0.01 part of zinc PCA, 0.005 parts of panthenol, 1.0 part of β-glucan, 1.0 part of purslane extract, 1.0 part of golden chamomile extract, 0.0005 parts of geranium extract, 1.0 part of peppermint extract, 1.0 part of aloe vera extract, and 0.0001 parts of sophora flavescens extract were mixed evenly to obtain an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition.

[0021] Example 2 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the amounts of each raw material used in Example 2 are as follows: 2.0 parts of C12-13 alcohol lactate, 0.05 parts of piroctone olamine salt, 1.0 part of menthol lactate, 1.0 part of zinc PCA, 2.0 parts of panthenol, 0.001 parts of β-glucan, 0.001 parts of purslane extract, 1.0 part of golden chamomile extract, 0.005 parts of geranium extract, 0.0001 parts of peppermint extract, 0.0001 parts of aloe vera extract, and 1.0 part of sophora flavescens extract are mixed evenly to obtain an antibacterial, dandruff-reducing, antipruritic, and oil-controlling composition.

[0022] Comparative Example 1 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the amounts of each raw material used in Comparative Example 1 are as follows: 0.2 parts of C12-13 alcohol lactate, 0.05 parts of piroctone olamine salt, 1.0 part of menthol lactate, 1.0 part of zinc PCA, 2.0 parts of panthenol, 0.001 parts of β-glucan, 3.0 parts of purslane extract, 1.0 part of golden chamomile extract, 1.0 part of geranium extract, 0.0001 parts of field peppermint extract, 0.0001 parts of aloe vera extract, and 3.0 parts of sophora flavescens extract are mixed evenly to obtain an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition.

[0023] Comparative Example 2 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that in Comparative Example 2, ginger root ( Zingiber officinale Roscoe Replace the purslane in Example 1.

[0024] Comparative Example 3 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the preparation methods of purslane, aloe vera, and sophora flavescens root in Comparative Example 3 are as follows: Purslane and black rice water were mixed and pulverized at a mass ratio of 1:2 to obtain purslane slurry (wherein the particle size of purslane in the slurry is ≤0.1cm). The slurry was then vacuum concentrated to 2 / 3 of its original volume at 60℃, and centrifuged to obtain the supernatant. The supernatant was mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of ethanol solution was 45% and the volume concentration of methanol solution was 45%) at a volume ratio of 1:8, and allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and the supernatant was concentrated and dried until the weight of the substance no longer changed, thus obtaining purslane extract. Aloe vera and black rice water were mixed and pulverized at a mass ratio of 1:2 to obtain Aloe vera pulp (wherein the particle size of Aloe vera in the pulp is ≤0.1cm). The pulp was then vacuum concentrated to 2 / 3 of its original volume at 60℃, and centrifuged to obtain the supernatant. The supernatant was mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of ethanol solution was 45% and the volume concentration of methanol solution was 45%) at a volume ratio of 1:8, and allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and the supernatant was concentrated and dried until the weight of the substance no longer changed, thus obtaining Aloe vera extract. Sophora flavescens root and black rice water were mixed and pulverized at a mass ratio of 1:2 to obtain Sophora flavescens root slurry (wherein the particle size of Sophora flavescens root in the slurry is ≤0.1cm). Then, the slurry was vacuum concentrated to 2 / 3 of its original volume at 60℃, and then centrifuged to obtain the supernatant. The supernatant was mixed with an alcohol solution (the alcohol solution was prepared by mixing methanol solution and ethanol solution at a volume ratio of 1:1, where the volume concentration of ethanol solution was 45% and the volume concentration of methanol solution was 45%) at a volume ratio of 1:8, and then allowed to stand for 6 hours. After centrifugation, the supernatant was obtained, and then concentrated and dried until the weight of the substance no longer changed to obtain Sophora flavescens root extract. Comparative Example 4 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the preparation methods for the stems of golden chamomile, geranium, and field mint in Comparative Example 4 are as follows: Golden chamomile was washed and dried to obtain dried golden chamomile (moisture content 20%). Using isobutane as the extractant, golden chamomile and extractant were subjected to subcritical extraction at a mass-volume ratio of 1g:12mL (temperature 45℃, pressure 5MPa, time 4h) to obtain golden chamomile extract. The stems of geranium were washed and dried to obtain dried geranium stems (moisture content 20%). Using isobutane as the extractant, the geranium stems and extractant were subjected to subcritical extraction at a mass-volume ratio of 1g:12mL (temperature 45℃, pressure 5MPa, time 4h) to obtain geranium stem extract. The field mint was washed and dried to obtain dried field mint (moisture content of 20%); using isobutane as the extractant, the field mint and the extractant were subjected to subcritical extraction at a mass-volume ratio of 1g:12mL (temperature of 45℃, pressure of 5MPa, time of 4h) to obtain field mint extract. Comparative Example 5 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that in Comparative Example 5, a 90% ethanol solution was used instead of the 45% ethanol solution in Example 1.

[0025] Comparative Example 6 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that propane is used instead of isobutane in Comparative Example 6.

[0026] Comparative Example 7 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the preparation methods for purslane, aloe vera, sophora flavescens, golden chamomile, geranium or mint in Comparative Example 7 are as follows: Plant samples, water, and cellulase were mixed at a mass ratio of 1:18:0.002 and enzymatically hydrolyzed at 32°C for 6 hours. After enzyme inactivation, purslane extract, aloe vera extract, sophora flavescens extract, golden chamomile extract, geranium extract, or field peppermint extract were obtained.

[0027] Comparative Example 8 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the purslane extract, aloe vera extract, sophora flavescens extract, golden chamomile extract, geranium extract or peppermint extract used in Comparative Example 8 were purchased conventionally.

[0028] Comparative Example 9 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that in Comparative Example 9, water was used instead of black rice water to prepare golden chamomile extract, geranium extract or field peppermint extract, respectively.

[0029] Comparative Example 10 A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, comprising the following steps: The only difference from Example 1 is that the alcohol solution used in Comparative Example 10 is an ethanol solution (wherein the volume concentration of the ethanol solution is 45%).

[0030] Application Example 1 The compositions prepared in Examples 1-2 and Comparative Examples 1-10 were dissolved in PBS to obtain test solutions with a final concentration of 0.1 g / mL, which were then used for testing. Malassezia furfur BNCC3373008 was used as the test strain (effective viable count of 10^6). 7 The bacterial suspension was prepared by adding 0.2 mL of bacterial suspension to each culture medium containing 2% olive oil agar and spreading it evenly. Each medium was then placed in a sterile Oxford cup (8 mm in diameter). Each Oxford cup contained 100 μL of different test solutions. Each treatment was repeated three times. After incubation at constant temperature for 48 h, the diameter of the inhibition zone was measured. The results are shown in Table 1.

[0031] Table 1. Average diameter of inhibition zone in untreated samples (including Oxford cup diameter of 8 mm)

[0032] As shown in Table 1, the compositions prepared in Examples 1, 2, 3, and 8 exhibit good inhibitory effects against Malassezia furfur, meaning they possess excellent antibacterial and antipruritic effects. However, after changing the preparation method, the corresponding products showed a reduced inhibitory effect against Malassezia furfur.

[0033] Application Example 2 The compositions prepared in Examples 1-2, Comparative Examples 3 and 8 were dissolved in PBS to obtain test solutions with a final concentration of 1 g / mL for 5α-reductase activity testing.

[0034] Measurements in the blank control group: 100 μL of testosterone, 200 μL of Tris buffer, 15 μL of NADPH, and 15 μL of 5α-reductase were mixed and the A340 nm value (A0) was measured. After incubation at 37°C for 10 min, the A340 nm value (A1) was measured, and ΔA0 = (A0 - A1) / A0 was calculated. This procedure was performed in triplicate, and the average value was taken.

[0035] Determination of the positive group: 50 μL of 0.5% finasteride solution, 100 μL of testosterone, 200 μL of Tris buffer solution, 15 μL of NADPH and 15 μL of 5α-reductase were mixed and incubated at 37°C for 10 min. The A340nm value (An) was then measured. ΔAn = (A0 - An) / A0 was calculated. This procedure was performed in triplicate, and the average value was taken.

[0036] Determination of test samples: Mix 50 μL of each test solution, 100 μL of testosterone, 200 μL of Tris buffer, 15 μL of NADPH, and 15 μL of 5α-reductase, and incubate at 37°C for 10 min. Measure the A340nm value (An). Calculate ΔAn = (A0 - An) / A0. This procedure was performed in triplicate, and the average value was taken.

[0037] The results of the 5α-reductase activity inhibition test were calculated using the formula ΔAn = (ΔA0 - ΔAn) / ΔA0 × 100%, and the results are shown in Table 2.

[0038] Table 2 Results of 5α-reductase activity inhibition test

[0039] As shown in Table 2, the composition prepared using the technical solution of this invention exhibits a high inhibition rate against 5α-reductase, approaching that of the finasteride group. In contrast, the product in the comparative example also shows an inhibitory effect on 5α-reductase activity, but with a relatively low inhibition rate. This indicates that the technical solution of this invention can better inhibit 5α-reductase activity, resulting in better dandruff control and oil management.

[0040] Application Example 3 The compositions prepared in Examples 1-2 and Comparative Example 8 were dissolved in PBS to obtain test solutions with a final concentration of 1 g / mL for hyaluronidase activity inhibition testing. The specific process is as follows: In a 96-well plate, samples of different concentrations were mixed with 5 U / mL hyaluronidase solution by shaking and incubation. Sodium hyaluronate solution (0.03% w / v) was added and incubated again. Finally, 0.1% BSA solution was added and incubation continued. OD was then measured. 600nm The values ​​were used to determine the inhibitory effect of the test sample on hyaluronidase, and the results are shown in Table 3.

[0041] Hyaluronidase activity inhibition rate (%) = [(AB) - (CD)] / (AB) × 100%, where: A represents the OD of the control solution. 600nm Value (using acetate buffer solution instead of sample solution); B represents the OD of the control blank solution. 600nm Value (using acetate buffer solution instead of sample solution and enzyme solution); C is the OD of the sample solution to be tested. 600nm value; D is the OD of the blank sample solution. 600nm Value (using acetic acid buffer solution instead of enzyme solution).

[0042] Table 3 Hyaluronidase activity inhibition rate

[0043] As can be seen from the data in Table 3, the composition prepared using the technical solution of the present invention has excellent hyaluronidase activity inhibition effect. Therefore, the technical solution of the present invention has a soothing effect.

[0044] In summary, this invention utilizes subcritical extraction of purslane, aloe vera, and sophora flavescens to avoid the decomposition of active ingredients such as polyphenols, essential oils, and vitamins. This not only results in high activity of the active ingredients but also significantly improves safety. The use of a specific subcritical solvent eliminates solvent impurities and chemical contaminants. Furthermore, the extraction of golden chamomile, geranium, and field peppermint using ethanol solution is not only highly efficient but also deeply purified, removing impurities and facilitating the efficient separation of pesticide residues, heavy metals, and potentially allergenic proteins from the plant extracts, as well as removing plant pigments and unpleasant odor substances. Therefore, the technical solution provided by this invention can be used to prepare products for antibacterial, dandruff-reducing, antipruritic, and oil-controlling purposes.

[0045] Although the above embodiments have provided a detailed description of the present invention, they are only some embodiments of the present invention, and not all embodiments. People can obtain other embodiments based on these embodiments without creative effort, and these embodiments all fall within the protection scope of the present invention.

Claims

1. A method for preparing an antibacterial, anti-dandruff, antipruritic, and oil-controlling composition, characterized in that, Includes the following steps: C12-13 alcohol lactate, piroctone ketone ethanolamine salt, menthol lactate, zinc PCA, panthenol, β-glucan, purslane extract, golden chamomile extract, geranium extract, field pepper extract, aloe vera extract and sophora flavescens extract are mixed evenly to obtain an antibacterial, anti-dandruff, antipruritic and oil-controlling composition. The preparation method of the purslane extract, aloe vera extract or sophora flavescens extract is as follows: the plant sample is dried and subjected to subcritical extraction to obtain the plant extract; The preparation method of the golden chamomile extract, geranium extract or field peppermint extract is as follows: the plant sample is mixed with black rice water, homogenized, vacuum concentrated and centrifuged to obtain supernatant 1; an alcohol solution is added to supernatant 1, and the mixture is allowed to stand and centrifuged to obtain supernatant 2; supernatant 2 is concentrated and dried to obtain the plant extract. The alcohol solution includes: methanol solution and ethanol solution.

2. The preparation method according to claim 1, characterized in that, The composition comprises the following raw materials in parts by weight: C12-13 alcohol lactate 0.2-2.0 parts, piroctone olamine salt 0.05-1.0 parts, menthol lactate 0.1-1.0 parts, zinc PCA 0.01-1.0 parts, panthenol 0.005-2.0 parts, β-glucan 0.001-1.0 parts, purslane extract 0.001-1.0 parts, golden chamomile extract 0.0005-1.0 parts, geranium extract 0.0005-1.0 parts, peppermint extract 0.0001-1.0 parts, aloe vera extract 0.0001-1.0 parts, and sophora flavescens extract 0.0001-1.0 parts.

3. The preparation method according to claim 1, characterized in that, During subcritical extraction, the mass-to-volume ratio of plant sample to extractant is 1g:12-15mL; the water content of the plant sample is 15%-20%.

4. The preparation method according to claim 1 or 3, characterized in that, The extractant is isobutane.

5. The preparation method according to claim 1 or 3, characterized in that, The subcritical extraction temperature is 45-60℃, the pressure is 2-5MPa, and the time is 3-4h.

6. The preparation method according to claim 1, characterized in that, During homogenization, the mass ratio of plant sample to black rice water is 1:1-2; The method for preparing black rice water is as follows: black rice and water are mixed and soaked in a mass ratio of 1:10, then filtered to obtain black rice water.

7. The preparation method according to claim 1, characterized in that, At 60-65℃, it is vacuum concentrated to 1 / 3-2 / 3 of its original volume.

8. The preparation method according to claim 1, characterized in that, When left to stand, the volume ratio of supernatant 1 to alcohol solution is 1:6-8; In the alcohol solution, the volume ratio of methanol solution to ethanol solution is 1:1-2; The volume concentration of the ethanol solution is 45%-55%; the volume concentration of the methanol solution is 45%-55%.

9. The antibacterial, anti-dandruff, antipruritic, and oil-controlling composition obtained by the preparation method according to any one of claims 1-8.

10. The use of the composition of claim 9 in the preparation of one or more antibacterial, anti-dandruff, antipruritic, and oil-controlling products.

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