A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, and its preparation method.

Abstract

This invention relates to the field of functional food technology, specifically to a solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, and its preparation method. The solid beverage comprises the following ingredients by weight: 2-3 parts modified sodium alginate, 5-8 parts inulin, 2-4 parts orange peel, 3-6 parts red adzuki bean extract, 1.5-3 parts cassia seed extract, 1-2 parts bitter orange flower extract, 2-4 parts radish seed extract, 3-6 parts hawthorn, and 2-4 parts lotus leaf extract. This solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects has the functions of lowering lipids, promoting digestion, weight loss, and spleen strengthening. Combined with dietary fiber such as inulin and resistant dextrin, it helps maintain intestinal function. Modified sodium alginate improves emulsification and dissolving stability. This solid beverage can be used as an auxiliary conditioning drink for overweight and hyperlipidemic individuals.

Description

Technical Field

[0001] This invention relates to the field of functional food technology, specifically to a solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, and its preparation method. Background Technology

[0002] With the accelerated pace of modern life and changes in dietary structure, metabolic diseases such as obesity and hyperlipidemia have become significant health problems affecting the public. These diseases not only lead to changes in body shape but are also important risk factors for various chronic diseases such as cardiovascular and cerebrovascular diseases and diabetes. Therefore, developing safe, effective foods or beverages with specific health benefits to help regulate blood lipids, reduce weight, and improve digestive function has significant practical implications and market potential.

[0003] Currently, products on the market targeting lipid-lowering, weight-loss, and spleen-strengthening / digestion-aiding needs mainly include chemical drugs, traditional Chinese medicine preparations, and some functional foods. While chemical drugs have clear efficacy, they often come with certain side effects and are not suitable for long-term use. Traditional Chinese medicine decoctions or pills, although having certain advantages in conditioning the body, suffer from inconvenience in administration, poor taste, and difficulty in carrying, failing to meet modern people's demand for convenience. Therefore, solid beverage products that combine good taste, ease of consumption, and definite health benefits are increasingly favored.

[0004] Existing solid beverage products, especially those claiming to have effects such as lowering lipids and losing weight, mostly have the following problems:

[0005] Poor stability of active ingredients: Many bioactive plant extracts (such as flavonoids, saponins, terpenes, etc.) are sensitive to light, heat, and oxygen. They are prone to degradation or inactivation during the processing (such as drying and granulation) and long-term storage of solid beverages, leading to reduced product efficacy. Poor solubility and reconstitution: Due to the properties of the raw materials or limitations of the processing technology, some solid beverages dissolve slowly in water, easily resulting in clumping, precipitation, etc., affecting the consumer's drinking experience.

[0006] Therefore, how to develop a lipid-lowering and weight-loss solid beverage with better stability, solubility, efficiency, convenience, and user experience has become the technical problem to be solved by this invention. Summary of the Invention

[0007] To address the problems of existing technologies, this invention provides a solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, as well as its preparation method. This solid beverage has lipid-lowering, digestion-promoting, weight-loss, and spleen-strengthening effects. Combined with dietary fiber such as inulin and resistant dextrin, it helps maintain intestinal function, and modified sodium alginate improves emulsification and dissolving stability. This solid beverage can be used as a supplementary conditioning drink for overweight and hyperlipidemic individuals.

[0008] The technical solution of the present invention to solve the above problems is as follows:

[0009] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects includes the following ingredients by weight: 2-3 parts modified sodium alginate, 5-8 parts inulin, 2-4 parts orange peel, 3-6 parts red adzuki bean extract, 1.5-3 parts cassia seed extract, 1-2 parts bitter orange flower extract, 2-4 parts radish seed extract, 3-6 parts hawthorn, and 2-4 parts lotus leaf extract.

[0010] The modified sodium alginate is prepared as follows:

[0011] Sodium alginate was added to deionized water and dissolved by stirring at 45-60℃ to obtain an aqueous solution of sodium alginate. The pH was adjusted to 8.3-8.7 with sodium carbonate. An ethanol solution of octenyl succinic anhydride was added dropwise to the aqueous solution of sodium alginate. The reaction was maintained at pH 8.3-8.7 and temperature 30-40℃ for 2-3 hours. After the reaction was completed, the pH was adjusted to 6.5-7.5. The solution was filtered and spray-dried, with calcium chloride solution sprayed in simultaneously during the spraying process to obtain modified sodium alginate. The mass ratio of sodium alginate to octenyl succinic anhydride and calcium chloride was 10:0.8-1.2:0.2-0.4. The concentration of the sodium alginate solution was 2-5%. The volume percentage of octenyl succinic anhydride in the ethanol solution was 8-12%. The concentration of the calcium chloride solution was 5-8%. The feed rate of the filtrate to the feed rate of the calcium chloride solution was 20-30:1. The ethanol solution of the alkenyl succinic anhydride was added at a rate of 0.5-2 mL / min.

[0012] Preferably, the inulin is pre-modified. The method for modifying the inulin is as follows: inulin is added to a mixed solvent of glacial acetic acid and deionized water, stirred and dispersed into a uniform suspension, sodium carbonate is added to maintain the pH at 6.8-7.2, and acetic anhydride and adipic anhydride are added dropwise sequentially at 50-60℃ and 200-400 rpm. After the addition is complete, the reaction continues for 1.5-2.5 h. After the reaction is completed, the inulin is purified and dried to obtain modified inulin. The mass ratio of inulin, mixed solvent, acetic anhydride, and adipic anhydride is 100:110-130:3.5-4.5:0.5-0.7, and the mass ratio of glacial acetic acid to deionized water in the mixed solvent is 1:0.8-1.2. The dropping rate of both acetic anhydride and adipic anhydride is 0.8-1.5 mL / min.

[0013] Preferably, it also includes 5-15 parts of resistant dextrin, 15-25 parts of maltodextrin, 8-12 parts of glucose, and 0.2-0.5 parts of silicon dioxide.

[0014] The preparation method of the above-mentioned solid beverage with the effects of lowering lipids, slimming the body, strengthening the spleen and promoting digestion is as follows: mix all raw materials evenly and granulate them to obtain the product.

[0015] The present invention has the following beneficial effects:

[0016] This invention relates to a solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects. The ingredients—orange peel, red adzuki bean, cassia seed, bitter orange flower, radish seed, hawthorn, and lotus leaf—have lipid-lowering, digestion-promoting, weight-loss, and spleen-strengthening properties. Specifically, hawthorn, radish seed, and orange peel primarily strengthen the spleen and aid digestion; cassia seed and lotus leaf primarily clear heat and lower lipids; red adzuki bean promotes diuresis and eliminates dampness; and bitter orange flower regulates qi and harmonizes the middle jiao. This combination follows the traditional Chinese medicine principle of "strengthening the spleen and eliminating dampness, promoting digestion and relieving stagnation, clearing heat and promoting diuresis" to aid in weight loss. Simultaneously, the addition of dietary fiber such as inulin and resistant dextrin helps maintain intestinal function; maltodextrin and glucose provide a low-sweetness taste; silica prevents clumping; and modified sodium alginate enhances emulsification and mixing stability. This solid beverage has a wide range of applications; it can be used as a daily functional beverage or as an auxiliary conditioning beverage for overweight and hyperlipidemia individuals. Modified sodium alginate addresses the limitation of traditional sodium alginate's single function, endowing it with the dual functions of encapsulating active ingredients and improving product texture. First, under weakly alkaline conditions, octenyl succinic anhydride is grafted onto the sodium alginate molecular chain, introducing a hydrophobic octenyl chain and making the originally hydrophilic sodium alginate amphiphilic. This allows it to more effectively encapsulate and load various hydrophobic or lipophilic active ingredients (such as flavonoids and glycosides) contained in the formulation, improving the stability of these components during processing and storage, and potentially improving their dispersibility in water. Then, during spray drying, a calcium chloride solution is simultaneously sprayed in, causing calcium ions to undergo ionic cross-linking with the guluronic acid (G unit) on the sodium alginate chain, instantly forming an "egg-box" structure. This modified sodium alginate, during the preparation of solid beverage granules, further locks the active ingredients, initially encapsulated in octenyl succinic anhydride-sodium alginate, within a cross-linked network, forming more robust microcapsules or gel particles. This provides potential for intestinal targeting or sustained release (sodium alginate calcium is stable in the acidic environment of the stomach and gradually dissolves and releases in the neutral to weakly alkaline environment of the intestine). Simultaneously, this modification process yields modified sodium alginate powder with a cross-linked structure, which exhibits increased dissolution rate and forms a high-viscosity micronetwork, enhancing suspension. As a matrix for solid beverages, it provides better suspension, moisture resistance, and post-concentration texture. This modified sodium alginate is not merely a filler or colloid, but also an active functional carrier and structural agent, significantly improving the bioavailability and physical stability of the entire formulation system.

[0017] Furthermore, pre-modification of inulin enhances its physicochemical properties, making it more suitable for processing and synergistic with modified sodium alginate. This modification process, conducted under mild acid-catalyzed conditions, involves partial esterification of inulin with acetic anhydride and adipic anhydride, resulting in the substitution of some hydroxyl groups and the introduction of acetyl and adipic groups. This reduces the surface polarity of inulin, improving its thermal stability and acid / alkali resistance, making it more stable during subsequent granulation and reconstitution. The modified inulin retains its basic dietary fiber properties (prebiotic activity), and the introduction of hydrophobic segments may improve its compatibility and synergy with the modified sodium alginate. Additionally, the introduction of adipic anhydride may increase the flexibility of the molecular chain or its interaction with other components. The modification process is carried out while maintaining the pH near neutral, and low-temperature water is used for termination and washing to maximize the preservation of the inulin's prebiotic activity and remove byproducts and residual reagents. The resulting modified inulin is a functional ingredient with superior performance and greater stability. It can work synergistically with modified sodium alginate to serve as a dual-core "functional-structural" matrix for beverages.

[0018] The modified sodium alginate and modified inulin of this invention exhibit a multi-layered and progressive synergistic effect. Modified sodium alginate (with an amphiphilic, calcium-crosslinked structure) and modified inulin with enhanced hydrophobicity can jointly form a more stable composite colloidal network. This network can uniformly encapsulate the active ingredients of traditional Chinese medicine with varying hydrophilicity / hydrophobicity in the formulation, significantly improving their stability during processing and preparation, and optimizing the texture and suspension of the beverage. Simultaneously, sodium alginate, after crosslinking with calcium ions, is stable in the stomach, protecting all core components (including inulin) until they reach the intestines. Inulin, as a prebiotic, is first fermented by colonic probiotics, producing short-chain fatty acids and locally lowering the pH. This environment accelerates the disintegration of modified sodium alginate, thereby promoting the targeted release of its encapsulated active ingredients of traditional Chinese medicine in the colon, achieving a precise synergistic effect of pre-activating the intestinal environment with prebiotics and enhancing the release and action of traditional Chinese medicine components. Both provide a strong feeling of fullness. The fermented products of inulin and the slowly released lipid-lowering components of traditional Chinese medicine (such as substances from lotus leaves and cassia seeds) can work synergistically on multiple targets (inhibiting absorption and regulating synthesis). Inulin promotes the growth of probiotics and improves the intestinal microecology, laying the foundation for "strengthening the spleen". On this basis, the slowly released digestive promoting components such as hawthorn and radish seeds can more effectively play the role of "promoting digestion and relieving stagnation". Attached Figure Description

[0019] Figure 1 The results of serum lipid metabolism tests in animal experiments with solid beverages in Examples 1-6 and Comparative Examples 1-3 are as follows;

[0020] Figure 2 The results of liver triglyceride testing in animal experiments of solid beverages in Examples 1-6 and Comparative Examples 1-3 are shown. Detailed Implementation

[0021] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0022] All of the following raw materials are commercially available.

[0023] Inulin, white powder, Chengdu Wanxiang Hongrun Biotechnology Co., Ltd.; Orange peel powder, 100 mesh, Baoji Liupanyun Biotechnology Co., Ltd.; Red adzuki bean extract, 97% content, Shaanxi Sinote Biotechnology Co., Ltd.; Cassia seed extract, 10:1 specification, 100 mesh, Lanzhou Waterles Biotechnology Co., Ltd.; Bitter orange flower extract, 10:1 specification, 80 mesh, Lanzhou Waterles Biotechnology Co., Ltd.; Radish seed extract, 10:1 specification, 100 mesh, Lanzhou Waterles Biotechnology Co., Ltd.; Hawthorn, 100 mesh hawthorn powder, Cangzhou Dinghao Food Co., Ltd.; Lotus leaf extract, 100 mesh, Lanzhou Waterles Biotechnology Co., Ltd.; Sodium alginate, 99% active ingredient content, Guangdong Mingcheng Biotechnology Co., Ltd.; Octenyl succinic anhydride (2-octenyl succinic anhydride), 99% content, Wuhan Lanabai Pharmaceutical Chemical Co., Ltd.

[0024] Example 1

[0025] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects comprises the following ingredients by weight: 2.5 parts modified sodium alginate, 6 parts inulin, 3 parts tangerine peel, 5 parts red adzuki bean extract, 2 parts cassia seed extract, 1.5 parts bitter orange flower extract, 3 parts radish seed extract, 5 parts hawthorn, 4 parts lotus leaf extract, 10 parts resistant dextrin, 20 parts maltodextrin, 10 parts glucose, and 0.4 parts silicon dioxide.

[0026] The modified sodium alginate is prepared as follows:

[0027] Sodium alginate was added to deionized water and dissolved by stirring at 55°C to obtain an aqueous solution of sodium alginate. The pH was adjusted to 8.3-8.7 with a 1.0 mol / L sodium carbonate solution. An ethanol solution of octenyl succinic anhydride was added dropwise to the sodium alginate aqueous solution at a rate of 1 mL / min. The reaction was carried out at pH 8.3-8.7 and temperature 35°C for 2.5 h. After the reaction was completed, the pH was adjusted to 6.5-7.5 with 1 mol / L dilute hydrochloric acid. Free octenyl succinic anhydride was removed by filtration through a 0.2 µm micropore filter. The filtrate was spray-dried at an inlet air temperature of 170°C and an outlet air temperature of 80°C. A dual-fluid nozzle was used for spray drying, and calcium chloride solution was sprayed in simultaneously during the spraying process to obtain modified sodium alginate. The mass ratio of sodium alginate to octenyl succinic anhydride and calcium chloride is 10:1:0.2. The concentration of the sodium alginate solution is 3%. The volume percentage of octenyl succinic anhydride in the ethanol solution is 10%. The concentration of the calcium chloride solution is 5-8%. The feed rate of the filtrate is 2:1 with the feed rate of the calcium chloride solution.

[0028] The preparation method of the above-mentioned solid beverage with the effects of lowering lipids, promoting weight loss, strengthening the spleen, and aiding digestion is as follows:

[0029] Take 10% of the total maltodextrin and mix it evenly with sodium bicarbonate. Then add it to deionized water at 40℃ to prepare a slurry with a total concentration of 55%. The amount of sodium bicarbonate is 0.8% of the total solid raw materials. Heat the slurry to 85℃ and hold for 1 minute. Then immediately pour in all the remaining powder materials except for silica and stir to obtain a thermoplastic soft material. Granulate the soft material through a granulator. Then, keep the granules in a 60℃ fluidized bed dryer (low-temperature section at the front end) for 3 minutes. The sodium bicarbonate decomposes instantly when heated, forming micropores inside the granules. The surface is rapidly cooled and solidified in a glassy state, locking the micropores. Continue to heat to 75℃ and hold for 5 minutes. The moisture content of the granules is ≤4%. After discharge, spray an atomized ethanol solution of silica, where the mass ratio of silica to ethanol is 1:5. Ethanol is evaporated by hot air at 60℃ to obtain the finished granules.

[0030] Example 2

[0031] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects comprises the following ingredients by weight: 3 parts modified sodium alginate, 5 parts inulin, 4 parts tangerine peel, 3 parts red adzuki bean extract, 3 parts cassia seed extract, 1 part bitter orange flower extract, 4 parts radish seed extract, 3 parts hawthorn, 4 parts lotus leaf extract, 5 parts resistant dextrin, 25 parts maltodextrin, 8 parts glucose, and 0.5 parts silicon dioxide.

[0032] The modified sodium alginate is prepared as follows:

[0033] Sodium alginate was added to deionized water and dissolved by stirring at 60°C to obtain an aqueous solution of sodium alginate. The pH was adjusted to 8.3-8.7 with a 1.0 mol / L sodium carbonate solution. An ethanol solution of octenyl succinic anhydride was added dropwise to the sodium alginate aqueous solution at a rate of 2 mL / min. The pH was maintained at 8.3-8.7 and the temperature at 30°C for 3 hours. After the reaction was completed, the pH was adjusted to 6.5-7.5 with 1 mol / L dilute hydrochloric acid. Free octenyl succinic anhydride was removed by filtration through a 0.2 µm micropore filter. The filtrate was spray-dried with an inlet air temperature of 180°C and an outlet air temperature of 85°C. A dual-fluid nozzle was used for spray drying, and calcium chloride solution was sprayed in simultaneously during the spraying process to obtain modified sodium alginate. The mass ratio of sodium alginate to octenyl succinic anhydride and calcium chloride is 10:0.8:0.4. The concentration of the sodium alginate solution is 5%. The volume percentage of octenyl succinic anhydride in the ethanol solution is 8%. The concentration of the calcium chloride solution is 8%. The feed rate of the filtrate to the feed rate of the calcium chloride solution is 20:1.

[0034] The preparation method of the solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects described above is the same as in Example 1.

[0035] Example 3

[0036] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects comprises the following ingredients by weight: 2 parts modified sodium alginate, 8 parts inulin, 2 parts tangerine peel, 6 parts red adzuki bean extract, 1.5 parts cassia seed extract, 2 parts bitter orange flower extract, 2 parts radish seed extract, 6 parts hawthorn, 2 parts lotus leaf extract, 15 parts resistant dextrin, 15 parts maltodextrin, 12 parts glucose, and 0.2 parts silicon dioxide.

[0037] The modified sodium alginate is prepared as follows:

[0038] Sodium alginate was added to deionized water and dissolved by stirring at 45°C to obtain an aqueous solution of sodium alginate. The pH was adjusted to 8.3-8.7 with a 1.0 mol / L sodium carbonate solution. An ethanol solution of octenyl succinic anhydride was added dropwise to the sodium alginate aqueous solution at a rate of 0.5 mL / min. The reaction was maintained at pH 8.3-8.7 and temperature 30-40°C for 2 hours. After the reaction was completed, the pH was adjusted to 6.5-7.5 with 1 mol / L dilute hydrochloric acid. Free octenyl succinic anhydride was removed by filtration through a 0.2 µm micropore filter. The filtrate was spray-dried at an inlet air temperature of 160°C and an outlet air temperature of 75°C. A dual-fluid nozzle was used for spray drying, and calcium chloride solution was sprayed simultaneously during the spraying process to obtain modified sodium alginate. The mass ratio of sodium alginate to octenyl succinic anhydride and calcium chloride is 10:1.2:0.2. The concentration of the sodium alginate solution is 2%. The volume percentage of octenyl succinic anhydride in the ethanol solution is 12%. The concentration of the calcium chloride solution is 5%. The feed rate of the filtrate to the feed rate of the calcium chloride solution is 30:1.

[0039] The preparation method of the solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects described above is the same as in Example 1.

[0040] Example 4

[0041] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, wherein the inulin is pre-modified, and the method for modifying the inulin is as follows:

[0042] The inulin was pre-modified. The modification method was as follows: inulin was added to a mixed solvent of glacial acetic acid and deionized water, stirred and dispersed into a uniform suspension, sodium carbonate was added to maintain the pH at 6.8-7.2, and acetic anhydride and adipic anhydride were added dropwise at 1 mL / min under stirring at 55°C and 300 rpm. After the addition was complete, the reaction continued for 2 hours. After the reaction was completed, 4°C reverse osmosis water was immediately sprayed in to terminate the reaction. The mixture was then filtered by plate and frame filter press, and the filter cake was washed three times countercurrently with 4°C reverse osmosis water. It was then vacuum dried at 60°C until the moisture content was ≤5%, and pulverized through an 80-mesh sieve to obtain modified inulin. The mass ratio of inulin, mixed solvent, acetic anhydride, and adipic anhydride was 100:120:4:0.6, and the mass ratio of glacial acetic acid to deionized water in the mixed solvent was 1:1. The rest was the same as in Example 1.

[0043] Example 5

[0044] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects is disclosed. The inulin is pre-modified. The modification method for the inulin is as follows: inulin is added to a mixed solvent of glacial acetic acid and deionized water, stirred and dispersed into a uniform suspension, sodium carbonate is added to maintain the pH at 6.8-7.2, and acetic anhydride and adipic anhydride are added dropwise at 0.8 mL / min under stirring at 50°C and 400 rpm. After the addition is complete, the reaction continues for 1.5 h. Immediately after the reaction is complete, 4°C reverse osmosis water is sprayed in to terminate the reaction. The mixture is then filtered using a plate and frame filter press. The filter cake is washed three times countercurrently with 4°C reverse osmosis water, vacuum dried at 60°C until the moisture content is ≤5%, and pulverized through an 80-mesh sieve to obtain modified inulin. The mass ratio of inulin, mixed solvent, acetic anhydride, and adipic anhydride is 100:110:4.5:0.5, and the mass ratio of glacial acetic acid to deionized water in the mixed solvent is 1:0.8. The rest is the same as in Example 1.

[0045] Example 6

[0046] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects is disclosed. The inulin is pre-modified. The modification method for the inulin is as follows: inulin is added to a mixed solvent of glacial acetic acid and deionized water, stirred and dispersed into a uniform suspension, sodium carbonate is added to maintain the pH at 6.8-7.2, and acetic anhydride and adipic anhydride are added dropwise at 1.5 mL / min under stirring at 60°C and 200 rpm. After the addition is complete, the reaction continues for 2.5 h. Immediately after the reaction is complete, 4°C reverse osmosis water is sprayed in to terminate the reaction. The mixture is then filtered using a plate and frame filter press. The filter cake is washed three times countercurrently with 4°C reverse osmosis water, vacuum dried at 60°C until the moisture content is ≤5%, and pulverized through an 80-mesh sieve to obtain modified inulin. The mass ratio of inulin, mixed solvent, acetic anhydride, and adipic anhydride is 100:130:3.5:0.7, and the mass ratio of glacial acetic acid to deionized water in the mixed solvent is 1:1.2. The rest is the same as in Example 1.

[0047] Comparative Example 1

[0048] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects is made by replacing modified sodium alginate with ordinary sodium alginate, with the rest being the same as in Example 1.

[0049] Comparative Example 2

[0050] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects is prepared by replacing modified sodium alginate with ordinary sodium alginate, with the rest being the same as in Example 4.

[0051] Comparative Example 3

[0052] A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects is prepared as follows: all dry materials are poured into a three-dimensional motion mixer and dry-mixed for 5 minutes. A mixture of ethanol and water is sprayed in a 1:1 volume ratio to wet the material until it can be formed into a ball when squeezed in the hand. The amount of the mixed solvent is 8% of the total mass of the dry materials. The mixture is then granulated and dried with hot air at 60°C for 90 minutes until the moisture content is ≤5%. The granules are then passed through a 14-mesh sieve to obtain the final product.

[0053] Performance testing:

[0054] 1. Solubility

[0055] Take 10g of the solid beverages from Examples 1-6 and Comparative Examples 1-3, dissolve them separately in 300ml of water at 40℃, stir to dissolve and time, and record the dissolution time; the results are shown in Table 1. 2. Evaluation of the weight loss effect on obese rats:

[0056] Modeling: Eighty male SD rats weighing 110±5g were randomly divided into 11 groups of 9 each. One group was the normal group (average weight 108.6g), and the rest were the obese group (average weight 107.8g). The normal group was fed with normal feed (normal rats), and the obese group was fed with high-fat feed. The feeding was carried out for 4 weeks.

[0057] 0.2g of the solid beverages obtained in Examples 1-6 and Comparative Examples 1-3 were diluted with distilled water and administered by gavage to groups 3 through 11. Groups 1 and 2 were administered distilled water only. Group 1 served as the normal control group, and Group 2 served as the model control group. The administration continued for 4 weeks. During the administration period, except for the normal control group which was given regular feed, the others continued to be fed a high-calorie feed. After the experiment, body weight fraction, body fat weight, and fat / body weight ratio were measured. The data are shown in Table 1.

[0058] Blood was collected from the eyes on the last day of the experiment. Rats were fasted for 12 hours before sacrifice, and their livers were harvested afterward. Serum and liver levels of cholesterol (cholesterol ELISA kit, Shanghai Fusheng Industrial Co., Ltd.), serum triglycerides (TG spectrophotometric assay kit), high-density lipoprotein (HDL) ELISA kit, and low-density lipoprotein (LDL) ELISA kit were detected using commercially available kits. All kits were purchased from Shanghai Fusheng Industrial Co., Ltd. The results are shown in Table 1.

[0059] Table 1. Results of Solubility Test

[0060]

[0061] Table 2. Results of animal experiments

[0062]

[0063] As shown in Table 1, Examples 1-6, which used modified raw materials (sodium alginate and inulin) and a thermoplastic microporous granulation process, all had dissolution times of less than 30 seconds. Example 4, with dual modification, achieved the best dissolution performance with only 22 seconds. In contrast, Comparative Examples 1-3, using ordinary raw materials or traditional processes, had dissolution times extended to 46-68 seconds, accompanied by agglomeration or suspended particles. This indicates that raw material modification effectively improved hydrophilic dispersibility, while the microporous structure formed by the granulation process of this invention greatly promoted water penetration and component dissolution, laying a solid foundation for a good mixing experience and application of the product.

[0064] From Table 2, Figure 1 , Figure 2 It was found that after 8 weeks of intervention, all treatment groups effectively inhibited obesity and related lipid metabolism disorders induced by a high-fat diet. All examples and comparative examples showed significantly better results than the model control group in key indicators such as final body weight, body fat mass, and serum TC, TG, and LDL-C, confirming the clear regulatory effect of the formulation. Comparing Example 1 (modified sodium alginate) with Comparative Example 1 (ordinary sodium alginate), the former showed superior improvement in all indicators, demonstrating the effectiveness of sodium alginate modification. Comparative Example 3, which used traditional wet granulation, had the worst efficacy indicators among all treatment groups, highlighting the positive role of the "thermoplastic granulation-instantaneous pore formation" process of this invention in improving bioavailability or functional performance. Optimal synergistic effect: Example 4 (modified sodium alginate + modified inulin) showed the best overall efficacy among all test groups. Its final weight (270.5g) and body fat (19.5g) were closest to those of the normal control group, and its lipid profile (lowest TC, TG, and LDL-C, highest HDL-C) and liver TG showed the most comprehensive and significant improvement. This strongly demonstrates that the specific modification treatment of the two core raw materials produced a synergistic effect.

[0065] Compared to Comparative Example 3, the preparation method of the above embodiment utilizes controlled thermal decomposition technology of sodium bicarbonate to simultaneously achieve microstructure design of particles and protection of heat-sensitive components, resulting in the following significant advantages: A thermoplastic soft material is formed by mixing the remaining powder with an 85°C hot slurry, followed by a 60°C initial drying stage to rapidly decompose sodium bicarbonate, creating uniform micropores within the particles. Subsequently, the surface is solidified in a glassy state to lock the pores, forming a loose particle structure with high porosity. This structure greatly increases the specific surface area and capillary action of the particles in contact with water, allowing the product to quickly penetrate and disperse upon contact with water, avoiding clumping and providing an excellent mixing experience. Simultaneously, the relatively mild step-drying method (60°C followed by 75°C), and the low temperature and short time of the crucial foaming and molding stage, minimize the thermal degradation loss of active ingredients of traditional Chinese medicine, modified sodium alginate, and functional factors such as inulin during granulation. The dense glassy shell rapidly formed on the particle surface, along with the internal microporous structure, effectively blocks moisture and oxygen during storage, improving product stability and extending shelf life. This method is simple and efficient, resulting in particles with good flowability and suitable density. Finally, a silica-ethanol solution is sprayed in for surface treatment, further preventing moisture and clumping, and ensuring powder flowability. In summary, this process not only solves the common solubility problem in solid beverages, but also actively protects the core functional ingredients during processing through physical structure design, achieving simultaneous improvements in product performance, stability, and production efficiency.

[0066] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0067] Although embodiments of this application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects, characterized in that, The ingredients are as follows by weight: 2-3 parts modified sodium alginate, 5-8 parts inulin, 2-4 parts orange peel, 3-6 parts red adzuki bean extract, 1.5-3 parts cassia seed extract, 1-2 parts bitter orange flower extract, 2-4 parts radish seed extract, 3-6 parts hawthorn, and 2-4 parts lotus leaf extract. The modified sodium alginate is prepared as follows: Sodium alginate was added to deionized water and stirred at 45-60℃ to dissolve, yielding an aqueous solution of sodium alginate. The pH was adjusted to 8.3-8.7 with sodium carbonate. An ethanol solution of octenyl succinic anhydride was added dropwise to the aqueous solution of sodium alginate. The reaction was carried out at pH 8.3-8.7 and temperature 30-40℃ for 2-3 hours. After the reaction was completed, the pH was adjusted to 6.5-7.

5. The solution was filtered and then spray-dried, with calcium chloride solution sprayed in during the spraying process, to obtain modified sodium alginate.

2. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 1, characterized in that, The mass ratio of sodium alginate to octenyl succinic anhydride and calcium chloride is 10: 0.8-1.2:0.2-0.4, the concentration of the sodium alginate solution is 2-5%, the volume percentage of octenyl succinic anhydride in the ethanol solution is 8-12%, the concentration of the calcium chloride solution is 5-8%, and the feed rate of the filtrate to the feed rate of the calcium chloride solution is 20-30:

1.

3. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 1, characterized in that, The ethanol solution of the alkenyl succinic anhydride was added at a rate of 0.5-2 mL / min.

4. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 1, characterized in that, The inulin was pre-modified. The method for modifying the inulin was as follows: inulin was added to a mixed solvent of glacial acetic acid and deionized water, stirred and dispersed into a uniform suspension, sodium carbonate was added to maintain the pH at 6.8-7.2, and acetic anhydride and adipic anhydride were added dropwise at 50-60℃ and 200-400 rpm. After the addition was complete, the reaction was continued for 1.5-2.5 h. After the reaction was completed, the inulin was purified and dried to obtain modified inulin.

5. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 4, characterized in that, in, The mass ratio of inulin, mixed solvent, acetic anhydride, and adipic anhydride is 100:110-130:3.5-4.5:0.5-0.7, and the mass ratio of glacial acetic acid to deionized water in the mixed solvent is 1:0.8-1.

2.

6. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 4, characterized in that, The dropping rates of both acetic anhydride and adipic anhydride were 0.8-1.5 mL / min.

7. The solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects according to claim 1, characterized in that, It also includes 5-15 parts resistant dextrin, 15-25 parts maltodextrin, 8-12 parts glucose, and 0.2-0.5 parts silicon dioxide.

8. The method for preparing the solid beverage with lipid-lowering, weight-loss, spleen-strengthening, and digestion-aiding effects as described in any one of claims 1-7, characterized in that, Specifically, the raw materials are mixed evenly and granulated to obtain the final product.

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