Cleaning water supply device of vacuum freeze dryer

Abstract

The utility model relates to a cleaning water supply device of a vacuum freeze dryer, which comprises a water storage tank body, a cleaning and sterilizing pipeline component is connected onto the water storage tank body, and an alkali preparation component is connected onto the cleaning and sterilizing pipeline component. The utility model aims to provide the cleaning water supply device for the vacuum freeze dryer, which aims to overcome the existing defects, is simple in cleaning operation and effectively reduces secondary pollution.

Description

Technical Field

[0001] The utility model relates to a cleaning water supply device for a vacuum freeze dryer. Background Art

[0002] Cleaning is crucial in the pharmaceutical industry, especially in the vacuum freeze drying system. If a safe and reliable cleaning system is used to remove the residues in the freeze drying chamber, the cleanliness of the freeze drying process will be improved. The CIP system (Clean In Place online cleaning system) can effectively reduce or remove the residual substances in the freeze drying system.

[0003] The traditional method of cleaning a vacuum freeze dryer is to use injected water or purified water directly connected to the spray ball pipeline of the vacuum freeze dryer for water supply and cleaning. In this way, the pipeline cannot be cleaned and sterilized independently, and it is difficult to solve the problem of secondary pollution. Therefore, a vacuum freeze dryer cleaning water supply device is proposed to address the above problems. Utility Model Content

[0004] The utility model aims to overcome the existing defects and provide a vacuum freeze dryer cleaning water supply device, which has simple cleaning operation and effectively reduces secondary pollution.

[0005] The technical solution to achieve the above purpose is: a vacuum freeze dryer cleaning water supply device, including a water storage tank body, the water storage tank body is connected to a cleaning and sterilizing pipeline assembly, and the cleaning and sterilizing pipeline assembly is connected to an alkali preparation assembly.

[0006] Preferably, the cleaning and sterilization pipeline assembly includes a cleaning water interface and a steam inlet, the inlet of the water storage tank body is connected in parallel to a liquid inlet valve and a steam inlet valve, the other end of the liquid inlet valve is connected to the cleaning water interface; the other end of the steam inlet valve is connected to the steam inlet.

[0007] Preferably, the cleaning and sterilizing pipeline assembly further comprises a freeze dryer water inlet pipeline and a drainage pipeline, the freeze dryer water inlet pipeline is connected to the upper end of the water storage tank body, and the freeze dryer water inlet pipeline is sequentially connected in series with a circulation valve, a freeze dryer cleaning valve and a freeze dryer water inlet;

[0008] The drainage pipe is connected to the lower end of the water storage tank body, and is connected in series with a discharge valve and a water tank main drainage valve, and the end of the drainage pipe is a water supply outlet;

[0009] The freeze dryer water inlet pipe and the drainage pipe are communicated through a third pipe, and a booster pump is connected to the middle of the third pipe.

[0010] Preferably, the alkali preparation component comprises an alkali liquid barrel, the alkali liquid barrel is connected to the third pipeline via a fourth pipeline, and the fourth pipeline is connected in series with a metering pump and an alkali liquid supply valve in sequence.

[0011] Preferably, it also includes a drainage component, which includes a self-priming pump, the left end of the self-priming pump is connected to the freeze dryer drain port, the upper end of the self-priming pump is connected to the cleaning water drain valve and the lower end is connected to the self-priming pump emptying valve, the right end of the fifth pipe is connected to the water supply outlet, and the left end is connected in parallel to the cleaning water drain valve and the self-priming pump emptying valve.

[0012] Preferably, the lower end of the boost pump is connected to the fifth pipeline through a sixth pipeline, and a boost pump drain valve is provided on the sixth pipeline.

[0013] Preferably, it also includes a differential pressure level gauge, wherein the upper contact of the differential pressure level gauge is connected to the inner upper end of the water storage tank body, and the lower contact of the differential pressure level gauge is connected to the inner lower end of the water storage tank body.

[0014] The beneficial effects of the utility model are as follows: the cleaning water supply device of the vacuum freeze dryer is provided with a cleaning and sterilizing pipeline assembly connected to the water storage tank body, an alkali preparation assembly connected to the cleaning and sterilizing pipeline assembly, and a drainage assembly connected to the freeze dryer; the cleaning and sterilizing pipeline assembly is adjustable and easy to operate; the cleaning process is carried out in closed production equipment, tanks, containers and pipelines, effectively reducing the probability of secondary pollution; and the structure is compact, the footprint is small, it is easy to install and maintain, and modular production can be realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic diagram of a cleaning water supply device for a vacuum freeze dryer of the utility model.

[0016] In the figure: 1. Water storage tank body; 2. Cleaning water interface; 3. Steam inlet; 4. Liquid inlet valve; 5. Steam inlet valve; 6. Freeze dryer water inlet pipe; 7. Drainage pipe; 8. Circulation valve; 9. Freeze dryer cleaning valve; 10. Freeze dryer water inlet; 11. Discharge valve; 12. Water tank main drain valve; 13. Third pipeline; 14. Booster pump; 15. Alkali liquid barrel; 16. Fourth pipeline; 17. Metering pump; 18. Alkali liquid supply valve; 19. Self-priming pump; 20. Freeze dryer drain; 21. Cleaning water drain valve; 22. Self-priming pump emptying valve; 23. Fifth pipeline; 24. Booster pump emptying valve; 25. Differential pressure level gauge; 26. Sixth pipeline. DETAILED DESCRIPTION

[0017] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inside", "outside" and the like indicate directions or positional relationships based on the directions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0018] The utility model will be further described below in conjunction with the accompanying drawings.

[0019] like Figure 1 As shown, a vacuum freeze dryer cleaning water supply device includes a water storage tank body 1, a cleaning and sterilizing pipeline assembly is connected to the water storage tank body 1, and an alkali preparation assembly is connected to the cleaning and sterilizing pipeline assembly. It also includes a differential pressure level gauge 25, the upper contact of the differential pressure level gauge 25 is connected to the upper end of the water storage tank body 1, and the lower contact of the differential pressure level gauge 25 is connected to the lower end of the water storage tank body 1.

[0020] like Figure 1 As shown, the cleaning and sterilizing pipeline assembly includes a cleaning water interface 2 and a steam inlet 3. The cleaning water interface 2 can be connected to purified water or injection water. The inlet of the water storage tank body 1 is connected in parallel to a liquid inlet valve 4 and a steam inlet valve 5. The other end of the liquid inlet valve 4 is connected to the cleaning water interface 2; the other end of the steam inlet valve 5 is connected to the steam inlet 3. The cleaning and sterilizing pipeline assembly also includes a freeze dryer water inlet pipeline 6 and a drainage pipeline 7. The freeze dryer water inlet pipeline 6 is connected to the upper end of the water storage tank body 1. The freeze dryer water inlet pipeline 6 is connected in series with a circulation valve 8, a freeze dryer cleaning valve 9 and a freeze dryer water inlet 10 in sequence; the drainage pipeline 7 is connected to the lower end of the water storage tank body 1 and is connected in series with a discharge valve 11 and a water tank main drainage valve 12 in sequence. The end of the drainage pipeline 7 is a water supply outlet; the freeze dryer water inlet pipeline 6 and the drainage pipeline 7 are connected through a third pipeline 13. A booster pump 14 is connected in the middle of the third pipeline 13.

[0021] Specifically, the alkali preparation component includes an alkali solution barrel 15 , which is connected to the third pipeline 13 via a fourth pipeline 16 , and the fourth pipeline 16 is connected in series with a metering pump 17 and an alkali solution supply valve 18 in sequence.

[0022] Specifically, it also includes a drainage component, which includes a self-priming pump 19, the left end of the self-priming pump 19 is connected to the freeze dryer drain port 20, the upper end of the self-priming pump 19 is connected to the cleaning water drain valve 21, and the lower end is connected to the self-priming pump emptying valve 22, the right end of the fifth pipeline 23 is connected to the water supply outlet, and the left end is connected in parallel to the cleaning water drain valve 21 and the self-priming pump emptying valve 22. The lower end of the booster pump 14 is connected to the fifth pipeline 23 through the sixth pipeline 26, and the booster pump emptying valve 24 is provided on the sixth pipeline 26.

[0023] Specifically, entering the self-cleaning project, purified water or injection water enters the water storage tank body 1 through the inlet valve 4, and at the same time, the discharge valve 11 and the water tank main drain valve 12 are opened to drain water until the set time and then the valve is closed. In the pipeline circulation washing stage, the inlet valve 4 is opened to let water in to the set liquid level meter water volume, and then the booster pump 14, circulation valve 8, and discharge valve 11 are opened to carry out pipeline circulation cleaning until the set time, and then the discharge valve 11, the water tank main drain valve 12, and the booster pump emptying valve 24 are opened to discharge until the set time and then the valve is closed. Finally, the inlet valve 4, the discharge valve 11, and the water tank main drain valve 12 are opened to flush the tank body until the set time and then the valve is closed. The number of times for each cleaning stage can be set.

[0024] Specifically, when entering the self-sterilization project, the steam inlet valve 5 of the water tank is opened for preheating. After the pressure reaches the set value, the discharge valve 11 and the water tank main drain valve 12 are opened to drain the condensed water for the set time, and then the steam inlet valve 5, the discharge valve 11, the circulation valve 8, and the booster pump drain valve 24 are opened to sterilize the tank body and pipelines. The steam inlet valve 5 is intermittently opened and closed according to the set tank body pressure value. After the tank body temperature reaches the set sterilization temperature, it continues for the set time, and then the discharge valve 11 and the water tank main drain valve 12 are opened to exhaust and restore the pressure to the set pressure.

[0025] Specifically, for the water supply process of cleaning the vacuum freeze dryer, when cleaning the vacuum freeze dryer, open the liquid inlet valve 4 to store water in the water storage tank 1 to the set liquid level, then open the booster pump 14, the discharge valve 11, and the circulation valve 8 for self-circulation to ensure the supply of cleaning water pressure. When the vacuum freeze dryer needs cleaning water, close the circulation valve 8 and open the freeze dryer cleaning valve 9 to supply water to the vacuum freeze dryer. When no water is needed, open the circulation valve 8 and close the freeze dryer cleaning valve 9 for self-circulation. At the same time, when the vacuum freeze dryer body is cleaned and drained, open the self-priming pump 19 and the cleaning water drain valve 21 to drain. When acid and alkali cleaning is required, open the metering pump 17 and the alkali liquid supply valve 18 to proportionate the liquid through the metering pump 17 and the water storage tank 1 The liquid level enters the self-circulation of the water supply system, and the vacuum freeze dryer body is cleaned with acid and alkali according to the cleaning requirements.

[0026] The vacuum freeze dryer has a cleaning water supply device, an adjustable cleaning program and simple operation. The cleaning process is carried out in closed production equipment, tanks, containers and pipelines, effectively reducing the probability of secondary pollution. It has a compact structure, a small footprint, is easy to install and maintain, and can realize modular production.

[0027] The cleaning water supply device of the vacuum freeze dryer mainly includes the steps of pre-rinsing, pipeline circulation cleaning and final washing and rinsing; the steps of self-sterilization process water tank disinfection, steam introduction, condensed water discharge, steam pulse sterilization and purging and re-pressurization, etc., so as to ensure the cleanliness and safety of the cleaning water supply of the vacuum freeze dryer, and further ensure the safe production of the product.

[0028] The above embodiments are only used to illustrate the technical solution of the utility model, rather than to limit it. Although the utility model is described in detail with reference to the above embodiments, ordinary technicians in this field should understand that they can still modify the technical solutions recorded in the above embodiments, or replace some or all of the technical features therein with equivalents. These modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the utility model.

Claims

1. A vacuum freeze dryer cleaning water supply device, characterized in that: It comprises a water storage tank body (1), the water storage tank body (1) is connected to a cleaning and sterilizing pipeline assembly, and the cleaning and sterilizing pipeline assembly is connected to an alkali preparation assembly; The cleaning and sterilizing pipeline assembly comprises a cleaning water interface (2) and a steam inlet (3); the inlet of the water storage tank body (1) is connected in parallel to a liquid inlet valve (4) and a steam inlet valve (5); the other end of the liquid inlet valve (4) is connected to the cleaning water interface (2); the other end of the steam inlet valve (5) is connected to the steam inlet (3); The cleaning and sterilizing pipeline assembly further comprises a freeze dryer water inlet pipeline (6) and a drainage pipeline (7), wherein the freeze dryer water inlet pipeline (6) is connected to the upper end of the water storage tank body (1), and the freeze dryer water inlet pipeline (6) is sequentially connected in series to a circulation valve (8), a freeze dryer cleaning valve (9) and a freeze dryer water inlet (10); The drainage pipe (7) is connected to the lower end of the water storage tank body (1) and is connected in series with a discharge valve (11) and a water tank main drainage valve (12) in sequence, and the end of the drainage pipe (7) is a water supply outlet; The freeze dryer water inlet pipe (6) and the drainage pipe (7) are connected via a third pipe (13), and a booster pump (14) is connected to the middle of the third pipe (13); The alkali preparation component comprises an alkali liquid barrel (15), the alkali liquid barrel (15) is connected to the third pipeline (13) through a fourth pipeline (16), and the fourth pipeline (16) is connected in series with a metering pump (17) and an alkali liquid supply valve (18); The invention also comprises a drainage component, wherein the drainage component comprises a self-priming pump (19), the left end of the self-priming pump (19) is connected to the freeze dryer drainage port (20), the upper end of the self-priming pump (19) is connected to the cleaning water drainage valve (21), and the lower end is connected to the self-priming pump emptying valve (22), the right end of the fifth pipeline (23) is connected to the water supply outlet, and the left end is connected in parallel to the cleaning water drainage valve (21) and the self-priming pump emptying valve (22).

2. The vacuum freeze dryer cleaning water supply device according to claim 1, characterized in that: The lower end of the booster pump (14) is connected to the fifth pipeline (23) via a sixth pipeline (26), and a booster pump drain valve (24) is provided on the sixth pipeline (26).

3. The vacuum freeze dryer cleaning water supply device according to claim 1, characterized in that: It also comprises a differential pressure level gauge (25), wherein the upper contact of the differential pressure level gauge (25) is connected to the internal upper end of the water storage tank body (1), and the lower contact of the differential pressure level gauge (25) is connected to the internal lower end of the water storage tank body (1).

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