Slender surgical instrument, ablation optical fiber assembly for laser interstitial hyperthermia and laser interstitial hyperthermia system

Abstract

The utility model provides a slender surgical instrument, an ablation optical fiber assembly for laser interstitial substance thermotherapy and a laser interstitial substance thermotherapy system.The slender surgical instrument comprises a slender component, and the slender component is used for being matched with a sleeve part connected to the outer side of the slender component in a sleeving mode and can move relative to the sleeve part during use; one of the slender component and the sleeve piece is provided with a position indicating part, the other one of the slender component and the sleeve piece is provided with a position matching part, the relative position change of the position indicating part and the position matching part is used for representing the relative movement position relation of the slender component and the sleeve piece, and the relative movement position relation comprises the relative movement distance and / or the relative rotation angle. By means of the relative position relation between the position indicating part and the position matching part, the slender component can be quickly and accurately adjusted to the preset axial position or angle, so that the ablation optical fiber can perform interventional therapy at the preset position without repeatedly moving the ablation optical fiber.

Description

Technical Field

[0001] The present application relates to the technical field of medical devices, and in particular to a slender surgical instrument, an ablation optical fiber assembly for laser interstitial thermal therapy, and a laser interstitial thermal therapy system. Background Art

[0002] During laser interstitial thermal therapy, in order to increase the treatment range, the ablation fiber needs to be moved forward and backward along the long axis direction to increase the axial ablation range, or in order to increase the ablation range or adjust the ablation direction, the ablation fiber needs to be rotated in the body to adjust the lateral light emission direction of the ablation fiber. At present, for the operations of moving the ablation fiber forward and backward and / or rotating it, the usual practice is for the doctor to enter the magnetic resonance room and measure and operate the ablation fiber based on experience. For example, when adjusting the axial treatment range, the doctor uses a ruler to measure the distance the fiber moves forward or backward while continuing to move forward or backward until it moves to the appropriate position; for example, when adjusting the lateral light emission direction of the fiber, the doctor uses a protractor to measure and rotate it until it rotates to the appropriate position.

[0003] The problems with the above method are: slow measurement (usually repeated movements and measurements are required to achieve the expected result), inaccurate control, low precision (errors), and easy destruction of the sterile environment causing bacterial contamination (consumables are required to be sterile before entering the human body, and are easily withdrawn from the body and re-entered during repeated movements, causing bacterial contamination). Utility Model Content

[0004] To this end, the first aspect of the present application provides a slender surgical instrument, comprising a slender member, which is used to cooperate with a sleeve member sleeved on the outside of the slender member and can move relative to the sleeve member when in use, one of the slender member and the sleeve member is provided with a position indicating portion, and the other is provided with a position matching portion, and the relative position change between the position indicating portion and the position matching portion is used to indicate the relative motion position relationship between the slender member and the sleeve member, and the relative motion position relationship includes a relative movement distance and / or a relative rotation angle.

[0005] Optionally, the position indicating portion includes a first ruler provided with a length scale and / or a second ruler provided with an angle scale, and the position matching portion includes a first mark for matching with the length scale and / or a second mark for matching with the angle scale;

[0006] The relative position change between the first scale and the first mark is used to indicate the relative movement distance between the elongated member and the sleeve member, and the relative position change between the second scale and the second mark is used to indicate the relative rotation angle between the elongated member and the sleeve member.

[0007] Optionally, the first scale is a wrapping layer fixedly connected to the outside of the slender member and extending axially along the slender member, the length scale is provided on the wrapping layer, and the first mark is a marking line provided on the sleeve member or the periphery of the proximal end of the sleeve member; and / or,

[0008] The second scale is a dial fixedly connected to the outer side of the sleeve and extending in the radial direction of the sleeve, the angle scale is arranged on the dial, and the second mark is an angle pointer fixedly connected to the elongated member.

[0009] Optionally, it also includes an operating portion fixedly connected to the proximal end of the slender member and used for manual operation by an operator and / or assembly with other instruments.

[0010] Optionally, the slender member is one of an ablation optical fiber, a deep electrode, a liquid nitrogen catheter, a water vapor injection catheter, and a radio frequency probe.

[0011] The second aspect of the present application provides an ablation optical fiber assembly for laser interstitial thermal therapy, comprising:

[0012] Ablation fiber;

[0013] a sleeve member, which is sleeved on the outside of the ablation optical fiber when in use, and the ablation optical fiber and the sleeve member can move relative to each other along the long axis, and the lumen of the sleeve member is used to construct an implantation channel for the ablation optical fiber to be implanted into the target tissue;

[0014] One of the ablation optical fiber and the sleeve is provided with a position indicating portion, and the other is provided with a position matching portion. The relative position change between the position indicating portion and the position matching portion along the long axis is used to indicate the relative movement distance between the ablation optical fiber and the sleeve along the long axis.

[0015] Optionally, the position indicating portion includes a first scale having a length scale, and the position matching portion includes a first mark for matching with the length scale.

[0016] Optionally, the first scale is a wrapping layer fixedly connected to the outside of the ablation optical fiber and extending along the long axis direction of the ablation optical fiber, the length scale is arranged on the wrapping layer, and the first mark is a marking line arranged on the sleeve or the periphery of the proximal end of the sleeve.

[0017] Optionally, the ablation optical fiber includes an ablation optical fiber body and a first cooling sleeve connected thereto, and the first scale or the first mark is arranged on the ablation optical fiber body or the first cooling sleeve; the ablation optical fiber body and the first cooling sleeve maintain a relative position unchanged during use; further, the first scale or the first mark is arranged on the inner tube or the outer tube of the first cooling sleeve, and the first cooling sleeve cools the ablation optical fiber body.

[0018] Optionally, the sleeve member includes a catheter, which is used to receive the ablation optical fiber therein and the ablation optical fiber can move along the long axis relative to the catheter; the ablation optical fiber assembly also includes a catheter guide structure for fixing the catheter relative to the target object.

[0019] Optionally, the catheter guide structure includes a guide member and a fastener, the guide member is used to be fixed to the target object, a guide channel is provided inside the guide member, after the guide member is fixed to the target object, the guide channel connects the inside of the target object with the outside, the catheter is connected to the guide channel and is locked with the guide member through the fastener.

[0020] Optionally, the guide member includes a self-tapping threaded member, in which the guide channel is provided, and the self-tapping threaded member is used to be screwed onto a pre-drilled hole in the skull of the target object; the fastener includes a nut for locking the catheter to the self-tapping threaded member.

[0021] Optionally, the catheter guiding structure is arranged at the end of a robotic arm of the surgical robot.

[0022] Optionally, the catheter is a second cooling sleeve, a first channel and a second channel are formed inside the second cooling sleeve, and the first channel and the second channel are connected at the distal end to form a cooling circuit for circulation of a cooling medium.

[0023] Optionally, the second cooling sleeve also includes a cooling medium inlet and outlet assembly for connecting a cooling medium source and the cooling circuit, and a screw-on leak-proof plug installed on the proximal side of the cooling medium inlet and outlet assembly and sealed with the ablation optical fiber.

[0024] Optionally, the sleeve assembly also includes a first sheath and / or a second sheath, the first sheath is sleeved on the outside of the ablation optical fiber and one end is fixedly connected to the proximal side of the tightening anti-leakage plug or the cooling medium inlet and outlet assembly, and the other end extends to the proximal end of the ablation optical fiber, and the second sheath is sleeved on the outside of the second cooling sleeve and one end is fixedly connected to the cooling medium inlet and outlet assembly, and the other end extends to the distal end of the second cooling sleeve.

[0025] Optionally, a position matching portion is provided at the proximal end of the first sheath.

[0026] Optionally, the first sheath and / or the second sheath are configured to be incompressible in the longitudinal direction.

[0027] Optionally, when the sleeve member includes a first jacket, the first jacket and the cooling medium inlet and outlet assembly form an integral rigid structure; or,

[0028] When the sleeve member includes a second sheath, the distal end of the second sheath may selectively extend to the catheter guide structure and be fixedly connected to the catheter guide structure, and the cooling medium inlet and outlet assembly, the catheter guide structure and the second sheath may form an integral rigid structure; or,

[0029] When the sleeve assembly includes a first sheath and a second sheath, a distal end of the second sheath can selectively extend to the catheter guide structure and be fixedly connected to the catheter guide structure, and the first sheath, the cooling medium inlet and outlet assembly, the catheter guide structure, and the second sheath form an integral rigid structure.

[0030] When the sleeve member includes a first sheath, the first sheath can be fixed manually during use, and then the axial movement of the ablation optical fiber can be operated.

[0031] When the sleeve assembly includes a first sheath, the ablation optical fiber assembly may also include a proximal fixing structure for fixing the proximal portion of the first sheath. When in use, the proximal side of the first sheath extends to the proximal fixing structure and is fixedly connected to the proximal fixing structure. The proximal fixing structure, the first sheath, and the cooling medium inlet and outlet assembly form an integral rigid structure; or the proximal fixing structure, the first sheath, the cooling medium inlet and outlet assembly, the catheter guide structure, and the second sheath form an integral rigid structure.

[0032] Optionally, when the ablation optical fiber assembly is used under the assistance of MRI, the ablation optical fiber and the proximal end of the first sheath are extended to a fiber control room next to the MRI room over a long distance, and the proximal end of the first sheath is fixed in the fiber control room by a proximal fixing structure or manually, so that the ablation optical fiber can be remotely controlled in the fiber control room;

[0033] The ablation optical fiber assembly also includes a proximal fixing structure disposed in the optical fiber control chamber for fixing the proximal portion of the first sheath. A proximal side of the first sheath can selectively extend to the proximal fixing structure and be fixedly connected to the proximal fixing structure.

[0034] Optionally, the ablation optical fiber assembly further comprises a fixing clamp which can selectively fix the first sheath to the ablation optical fiber.

[0035] Optionally, the proximal end of the ablation optical fiber is connected to a driving device for controlling the ablation optical fiber or a control unit for manual control by an operator.

[0036] Optionally, the position indicating portion further includes a second ruler having an angle scale, and the position matching portion further includes a second mark for matching with the angle scale, and the relative position change between the second ruler and the second mark is used to indicate the relative rotation angle between the optical fiber assembly and the sleeve assembly.

[0037] Optionally, the second scale is a disk fixedly connected to the outside of the sleeve and extending radially along the sleeve, the angle scale is arranged on the disk, and the second mark is an angle pointer fixedly connected to the ablation optical fiber and pointing to the angle scale.

[0038] Optionally, the ablation optical fiber includes an optical fiber bundle and an optical path adjustment structure, the optical fiber bundle includes multiple independent optical fibers; the multiple independent optical fibers are distributed circumferentially to form a circumferential optical fiber; the optical path adjustment structure is used to change the direction of lasers propagated or emitted by the multiple independent optical fibers so that the lasers are output toward the radial outer side of the ablation optical fiber; the laser energy in the independent optical fibers is configured to be controllable individually or in groups, so that various forms of laser distribution can be formed.

[0039] The third aspect of the present application provides a laser interstitial thermal therapy system, comprising the ablation fiber assembly and a laser generating assembly provided in the first aspect of the present application, wherein the laser generating assembly is connected to the ablation fiber.

[0040] The ablation fiber assembly for laser interstitial thermal therapy provided by the present application is provided with a position indicating portion on one of the ablation fiber and the sleeve, and a position matching portion on the other, and the relative position change of the position indicating portion and the position matching portion along the long axis is used to indicate the relative movement distance of the ablation fiber and the sleeve along the long axis, so that when adjusting the axial treatment range, the operator (such as a doctor) no longer needs to use the method of measuring and operating at the same time and repeatedly operating. With the help of the relative position relationship between the position indicating portion and the position matching portion, the operator can quickly identify the current axial position relationship between the ablation fiber and the sleeve and the axial distance that the ablation fiber needs to move, and can accurately adjust the ablation fiber to the preset axial position. In some cases, the operator can adjust it in place at one time, which effectively improves the operation efficiency and the control accuracy of the ablation fiber compared with the related technology. In addition, since the repeated movement of the ablation fiber is reduced or avoided, it is ensured that the ablation fiber will not be withdrawn from the patient's body and then re-entered, avoiding the problem of bacterial contamination of the patient's body by the external bacterial environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] In order to more clearly illustrate the specific implementation methods of the present application or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0042] Figure 1 is a schematic structural diagram of a slender surgical instrument provided according to an embodiment of the present application;

[0043] Figure 2 is a schematic structural diagram of an ablation optical fiber assembly provided according to an embodiment of the present application;

[0044] Figure 3 is a schematic diagram of a second scale and a second marking indicating structure in an ablation optical fiber assembly provided according to an embodiment of the present application;

[0045] Figure 4 is another structural schematic diagram of an ablation optical fiber assembly provided according to an embodiment of the present application;

[0046] Figure 5 It is a schematic diagram of an assembly structure of a second cooling sleeve and an ablation optical fiber in an ablation optical fiber assembly provided according to an embodiment of the present application;

[0047] Figure 6 It is a schematic diagram of another assembly structure of a second cooling sleeve and an ablation optical fiber in an ablation optical fiber assembly provided according to an embodiment of the present application;

[0048] Figure 7 It is a schematic diagram of an assembly structure of another second cooling sleeve and an ablation optical fiber in an ablation optical fiber assembly provided according to an embodiment of the present application;

[0049] Figure 8 This is a schematic diagram of the structure of an ablation optical fiber assembly for realizing remote control according to an embodiment of the present application;

[0050] Fig. 9 is another structural schematic diagram of an ablation optical fiber assembly for realizing remote control according to an embodiment of the present application;

[0051] Fig.10 It is another structural schematic diagram of an ablation optical fiber assembly for realizing remote control according to an embodiment of the present application;

[0052] Fig.11 is a schematic structural diagram of an optical fiber bundle according to an embodiment of the present application;

[0053] Fig.12 is a schematic diagram of structures of different laser distribution forms in multiple embodiments of the present application;

[0054] Fig.13 is a schematic structural diagram of another optical fiber bundle according to an embodiment of the present application;

[0055] Fig.14 yes Fig.13 A schematic diagram of the front view structure of

[0056] Fig.15 yes Fig.14 A side view schematic diagram of the structure;

[0057] Fig.16 is a cross-sectional schematic diagram of an ablation optical fiber assembly according to an embodiment of the present application;

[0058] Fig.17 is a cross-sectional schematic diagram of another ablation optical fiber assembly according to yet another embodiment of the present application;

[0059] Fig.18 It is a schematic diagram of a side cross-sectional structure when an ablation optical fiber adopts an optical path adjustment structure according to one embodiment of the present application;

[0060] Fig.19 is a schematic diagram of a side cross-sectional structure when an ablation optical fiber adopts another optical path adjustment structure according to another embodiment of the present application;

[0061] Fig. 20 Is adopted Fig.19 A schematic diagram of the axonometric structure of the optical fiber bundle when the optical path adjustment structure is in FIG.

[0062] Fig.21 is a schematic diagram of a laser ablation system according to an embodiment of the present application;

[0063] Fig. 22 It is a schematic diagram of another laser ablation system according to an embodiment of the present application.

[0064] Description of reference numerals:

[0065] 1101, operating part; 1102, first scale; 11021, length scale; 1103, slender member; 1104, ablation optical fiber; 1105, wrapping layer; 1030, second cooling sleeve; 1031, first outer tube; 1032, first inner tube; 1033, first supporting structure; 1034, second supporting structure; 1035, supporting member; 11051, first mark; 1201, first sheath; 1202, tightening anti-leakage plug; 1204, second sheath; 12031, cooling medium inlet member; 12032, cooling medium outlet member; 1301, nut; 1302, guide member; 13021, rotor; 13022, self-tapping threaded member; 1106, face plate; 1107, angle pointer; 1108, driving device; 1109, skull; 1110, pull ring;

[0066] 1. Fiber optic bundle; 101. Independent optical fiber; 102. Second inner tube; 103. Second outer tube; 104. Central optical fiber; 105. First channel; 106. Second channel; 107. Wedge-shaped structure; 108. Reflection cone; 2. Light output range; 3. Laser; 4. Connector; 5. Optical splitter; 6. Variable optical attenuator; 7. Optical path adjustment structure; 71. Reflection surface. DETAILED DESCRIPTION

[0067] The technical solution of the present application will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are part of the embodiments of the present application, rather than all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present application.

[0068] In the description of the present application, it should be noted that the terms "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second", and "third" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0069] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0070] In addition, the technical features involved in the different embodiments of the present application described below can be combined with each other as long as they do not conflict with each other.

[0071] In the description of the present application, "relative movement distance" includes the distance that the slender member 1103 or the ablation optical fiber 1104 moves forward relative to the sleeve member and the distance that it moves backward relative to the sleeve member; "relative rotation angle" includes the angle of clockwise rotation of the slender member 1103 or the ablation optical fiber 1104 relative to the sleeve member and the angle of counterclockwise rotation relative to the sleeve member.

[0072] “Advance” means that the elongated member 1103 or the ablation optical fiber 1104 moves toward the distal end of the sleeve relative to the sleeve; “retreat” means that the elongated member 1103 or the ablation optical fiber 1104 moves toward the proximal end of the sleeve relative to the sleeve.

[0073] “Distal end” refers to the end away from the operator; “proximal end” refers to the end close to the operator.

[0074] Example 1

[0075] Figure 1 A slender surgical instrument is shown, which is used as an interventional surgical instrument to enter the human body for interventional treatment. The slender surgical instrument includes a slender member 1103, which is used to cooperate with a sleeve member sleeved on the outside thereof and can move relative to the sleeve member when in use. One of the slender member 1103 and the sleeve member is provided with a position indicating portion, and the other is provided with a position matching portion. The relative position change between the position indicating portion and the position matching portion is used to indicate the relative motion position relationship between the slender member 1103 and the sleeve member, and the relative motion position relationship includes a relative movement distance and / or a relative rotation angle.

[0076] During use, the operator (e.g., a doctor) can quickly and accurately adjust the slender member 1103 to a preset axial position or angle by means of the relative position relationship between the position indicating portion and the position matching portion, so that the slender member 1103 can perform interventional treatment at the preset position. Compared with the related art, the slender surgical instrument of this embodiment can achieve the expected effect without repeated movement / rotation and measurement, and the control of the slender member 1103 is more precise and reduces errors. In addition, since the repeated movement of the slender member 1103 is reduced or avoided, it is ensured that the slender member 1103 will not be withdrawn from the patient's body and then re-entered, avoiding the problem of infection of the patient's body by the external bacterial environment.

[0077] Furthermore, the position indicating portion includes a first ruler 1102 provided with a length scale 11021, and the position matching portion includes a first mark 11051 for matching with the length scale 11021. In one embodiment, the first ruler 1102 is a wrapping layer 1105 fixedly connected to the outside of the elongated member 1103 and extending along the axial direction of the elongated member 1103, and the length scale 11021 is provided on the wrapping layer 1105; the first mark 11051 is a marking line provided on the sleeve member. When in use, the distance of the elongated member 1103 moving forward or backward relative to the sleeve member can be identified through the relative position relationship between the length scale 11021 on the wrapping layer 1105 and the marking line on the sleeve member.

[0078] It should be noted that, although the slender surgical instrument of this embodiment can usually avoid the operation of repeatedly moving / rotating the slender component 1103, it is not ruled out that in some cases it is still necessary to repeatedly move / rotate the slender component 1103 to achieve the expected treatment effect. It can be understood that the use of the slender surgical instrument of this embodiment can also improve the operational efficiency of repeatedly moving / rotating the slender component 1103 to achieve the expected effect.

[0079] The first mark 11051 is not limited to the marking line on the sleeve, and in other embodiments, the first mark 11051 can also be the periphery of the proximal end of the sleeve. The distance that the elongated member 1103 moves forward or backward relative to the sleeve can be identified through the indication of the periphery and the length scale 11021.

[0080] It should be noted that, as an alternative implementation, the first scale 1102 can also be set on the sleeve member, and the first mark 11051 can be set on the slender member 1103. As long as the relative movement relationship between the slender member 1103 and the sleeve member can be clearly and accurately reflected, it is allowed in this application.

[0081] Furthermore, in one embodiment, the position indicating portion further includes a second ruler provided with an angle scale, and the position matching portion includes a second mark for matching with the angle. The second ruler is a face plate 1106 fixedly connected to the outside of the sleeve member and extending in the radial direction of the sleeve member, and the angle scale is provided on the face plate 1106; the second mark is an angle pointer 1107 fixedly connected to the optical fiber. The clockwise rotation angle and counterclockwise rotation angle of the slender member 1103 relative to the sleeve member can be identified by the indication of the angle pointer 1107 and the angle scale. Similar to the first ruler 1102 and the first mark 11051, the second ruler and the second mark can also be interchanged, as long as the relative rotation relationship between the slender member 1103 and the sleeve member can be clearly and accurately reflected, it is allowed in this application.

[0082] In order to more clearly indicate the relative rotation angle relationship between the slender member 1103 and the sleeve member, a second scale with an angle scale is provided on the outer periphery of the face plate 1106, and the angle pointer 1107 is provided as an L-shaped pointer connected to the slender member 1103, with one edge overlapping the outer periphery of the face plate 1106 with a length exceeding the face plate 1106, so that when the slender member 1103 and the sleeve member rotate relative to each other, the L-shaped pointer forms a more intuitive corresponding relationship with the angle scale on the face plate 1106. Preferably, one edge of the angle pointer 1107 overlaps the top of the outer periphery of the face plate 1106.

[0083] In order to facilitate the operator's operation or to be used in conjunction with other instruments, the slender surgical instrument also includes an operating portion 1101 fixedly connected to the proximal end of the slender member 1103 for manual operation by the operator and / or assembly with other instruments. The operating portion 1101 can be a pull ring 1110 arranged at the proximal end of the slender member 1103, or an operating handle fixedly sleeved on the proximal end of the slender member 1103 for the convenience of the operator to hold. This application does not impose any special restrictions on this, as long as it can facilitate the operator's operation. The operating portion 1101 can also be used as a structure for assembly with other instruments, such as a progressive / rotation device, and the automation of the operation of the slender member 1103 is realized by assembling with the progressive / rotation device.

[0084] In this embodiment, the slender member 1103 can be one of an ablation optical fiber 1104, a deep electrode, a liquid nitrogen catheter, a water vapor injection catheter, and a radio frequency probe.

[0085] The sleeve member is used to establish an implantation channel for the slender member 1103 to enter the human body. Preferably, the sleeve member is a fixed sleeve, but is not limited to a fixed sleeve. According to actual needs, the sleeve member can also be set as a movable sleeve.

[0086] Example 2

[0087] During the laser interstitial thermal therapy, in order to increase the ablation range, the operator (e.g., doctor) needs to longitudinally move the ablation optical fiber 1104. The longitudinal movement includes forward movement, backward movement, or reciprocating movement between forward movement and backward movement. For laser interstitial thermal therapy, the longitudinal movement of the ablation optical fiber 1104 needs to be precisely controlled to achieve the expected treatment effect.

[0088] In the related art, in order to increase the axial ablation range, the operator uses a ruler to measure the distance that the ablation optical fiber 1104 moves forward or backward while continuing the operation of moving forward or backward until it moves to a suitable position.

[0089] The problems with related technologies are: slow measurement (usually repeated movements and multiple measurements are required to achieve the expected result), inaccurate control, low precision (errors), and easy destruction of the sterile environment causing bacterial contamination (consumables are required to be sterile before entering the body, and are easily withdrawn from the body and then re-entered during repeated movements, causing bacterial contamination).

[0090] Figure 2 The ablation fiber assembly for laser interstitial thermal therapy of this embodiment is shown. The ablation fiber assembly mainly includes an ablation fiber 1104 and a sleeve. The sleeve is sleeved on the outside of the ablation fiber 1104 and the ablation fiber 1104 and the sleeve can move relative to each other during use. The lumen of the sleeve is used to construct an implantation channel for the ablation fiber 1104 to be implanted in the body.

[0091] One of the ablation optical fiber 1104 and the sleeve is provided with a position indicating portion, and the other is provided with a position matching portion. The relative position change between the position indicating portion and the position matching portion along the long axis direction is used to indicate the relative movement distance between the ablation optical fiber 1104 and the sleeve along the long axis direction.

[0092] When adjusting the axial ablation range, the operator can quickly and accurately move the ablation optical fiber 1104 forward or backward by means of the relative position relationship between the position indicating part and the position matching part, so that the ablation optical fiber 1104 moves axially to the preset position. Compared with the related art, the ablation optical fiber 1104 assembly of this embodiment does not need to be repeatedly moved and measured to reach the expected axial position, and the control of the axial movement of the ablation optical fiber 1104 can be more precise and reduce errors; in addition, since the repeated movement of the ablation optical fiber 1104 is reduced or avoided, the ablation optical fiber 1104 will not be withdrawn from the patient's body and then re-entered, avoiding the problem of bacterial contamination of the patient's body by the external bacterial environment.

[0093] Furthermore, the position indicating portion includes a first scale 1102 provided with a length scale 11021 , and the position matching portion includes a first mark 11051 for matching with the length scale 11021 .

[0094] Since the ablation optical fiber 1104 is a slender structure and has low strength, it is difficult to process the length scale 11021 directly on the ablation optical fiber 1104. In order to reduce the processing difficulty of the length scale 11021 and improve the strength of the ablation optical fiber 1104 at the same time, in one embodiment, the first scale 1102 is set as a wrapping layer 1105 fixedly connected to the outside of the ablation optical fiber 1104 and extending along the axial direction of the ablation optical fiber 1104, and the length scale 11021 is set on the wrapping layer 1105; the first mark 11051 is a mark line set on the sleeve. When in use, the relative position relationship between the length scale 11021 on the wrapping layer 1105 and the mark line on the sleeve can be used to identify the distance that the ablation optical fiber 1104 moves longitudinally relative to the sleeve.

[0095] In order to facilitate the operator to read, the sleeve is preferably transparent, so that the operator can see the length scale 11021 on the wrapping layer 1105 through the sleeve, which is helpful for the operator to quickly identify the correspondence between the length scale 11021 and the identification line.

[0096] The length scale 11021 is processed on the wrapping layer 1105. The length scale 11021 can be processed on the outer surface of the wrapping layer 1105, or on the middle layer or bottom layer of the wrapping layer 1105, and there is no limitation to this.

[0097] The first mark 11051 is not limited to the marking line on the sleeve, and in other embodiments, the first mark 11051 can also be the periphery of the proximal end of the sleeve. The distance that the ablation optical fiber 1104 moves forward or backward relative to the sleeve can be identified by the indication of the periphery and the length scale 11021.

[0098] As an alternative embodiment, the first scale 1102 may also be set on the sleeve, and the first mark 11051 may be set on the ablation optical fiber 1104. As long as the relative movement relationship between the ablation optical fiber 1104 and the sleeve can be clearly and accurately reflected, it is allowed in this application.

[0099] As an alternative embodiment, the wrapping layer 1105 can be eliminated, and the first scale 1102 can be directly formed on the ablation optical fiber 1104. Specifically, it can be formed on the outer surface of the ablation optical fiber 1104, or it can be formed on the lower layer of the ablation optical fiber 1104, and this application does not limit this. The form of the length scale 11021 of the first scale 1102 is also not limited, and it can be a scale with graduation value scale lines, or it can be alternating color-changing stripes; when alternating color-changing stripes are used, the interval of the alternating color-changing stripes is also not limited, and it can be 1mm, 2mm or 5mm, etc. The production method of the scale and the alternating color-changing stripes is also not limited, and they can be produced by one of the processes of spray painting, silk screen printing, and laser engraving.

[0100] The wrapping layer 1105 can also be replaced by an adhesive sheet, on which the first scale 1102 is processed, and the adhesive sheet is bonded to the ablation optical fiber 1104 .

[0101] There is no restriction on the length of the first ruler 1102 and the length scale 11021. The first ruler 1102 and the length scale 11021 may cover the entire length of the ablation optical fiber 1104, or may only cover a portion of the length of the ablation optical fiber 1104. It is best to cover a portion of the length of the ablation optical fiber 1104 and be arranged at the proximal end of the ablation optical fiber 1104 to facilitate the operator's operation.

[0102] The sleeve member includes a catheter, which is used to receive the ablation optical fiber inside and the ablation optical fiber can move relative to the catheter along the long axis direction. The catheter is used to support and protect the ablation optical fiber and establish an implantation channel for the ablation optical fiber to enter the body.

[0103] In order to enable the ablation optical fiber 1104 to quickly and accurately enter a preset position in the body, the ablation optical fiber 1104 assembly of this embodiment further includes a catheter guide structure for fixing the catheter and the target object relative to each other.

[0104] like Figure 4 As shown, for example, when the target object is a human skull 1109, the sleeve guide structure includes a guide member 1302 and a fastener, a guide channel is provided inside the guide member, the guide member 1302 is used to be fixed to the target object, and after the guide member is fixed to the skull, the guide channel inside the guide member connects the inside of the skull with the outside world; thereafter, the catheter is connected to the guide channel and locked with the guide member by the fastener.

[0105] Furthermore, the guide member 1302 includes a self-tapping screw member 13022 and a rotor 13021, and the fastener includes a nut 1301. When in use, the self-tapping screw member 13022 is screwed onto a pre-drilled hole in the skull 1109 by means of the rotor 13021, and a guide channel is provided inside the self-tapping screw member 13022. The catheter is inserted into the guide channel and extended into the lesion position of the skull 1109, and then the catheter and the self-tapping screw member 13022 are screwed together by the nut 1301 to achieve the fixation of the catheter and the skull 1109, and then the ablation optical fiber 1104 is inserted into the catheter and extends into the lesion position through the self-tapping screw member 13022 for ablation treatment.

[0106] It should be noted that, usually, the distal end of the catheter is closed, and the ablation optical fiber 1104 does not contact the target tissue inside the catheter; but in some cases, the distal end of the catheter can be open, and the ablation optical fiber 1104 extends from the distal end of the catheter and directly contacts the target tissue. For example, when treating brain lesions, since the brain tissue is relatively soft, in some cases, the ablation optical fiber itself can pass through the brain tissue to reach the designated lesion location in the brain without using the distal end of the catheter to establish a support channel for it.

[0107] In one embodiment, the self-tapping threaded member 13022, the rotor 13021 and the nut 1301 are all rigid parts, and the self-tapping threaded member 13022 and the rotor 13021 are integrally arranged; in other embodiments, the rotor 13021 and the self-tapping threaded member 13022 can be detachable structures.

[0108] As an alternative embodiment, the catheter guide structure can also be set at the end of the mechanical arm of the surgical robot, that is, an equivalent guide structure is established using the end of the mechanical arm of the surgical robot. For example, when the target object is not the patient's skull 1109, there is no need to implant bone screws. When in use, a hole is punched in the designated position of the target object in advance, and then the robot is controlled to move the mechanical arm to the designated position. After that, the catheter is fixedly connected to the equivalent guide structure at the end of the mechanical arm and the lumen of the catheter is connected to the guide channel of the equivalent guide structure. Then, the ablation optical fiber 1104 is inserted into the lumen of the catheter and the guide channel of the equivalent guide structure in sequence and finally enters the patient's body. When the ablation position needs to be adjusted, the entirety can be moved by the mechanical arm.

[0109] In this embodiment, the catheter can be a second cooling sleeve 1030. A first channel and a second channel are formed inside the second cooling sleeve 1030, and the first channel and the second channel form a cooling circuit at the distal end. When in use, cooling medium (such as cooling water) is input into the cooling circuit to achieve cooling of the ablation optical fiber 1104 and the second cooling sleeve 1030.

[0110] There are many ways to form the first channel and the second channel inside the second cooling jacket 1030. Figure 5 As shown, the second cooling sleeve 1030 is composed of a first outer tube 1031 and a first inner tube 1032, the ablation optical fiber 1104 is located inside the first inner tube 1032, a first channel 105 is formed between the first outer tube 1031 and the first inner tube 1032, a second channel 106 is formed between the first inner tube 1032 and the ablation optical fiber 1104, and the first channel and the second channel are connected at the distal position to form a cooling circuit; in order to enhance the support strength of the second cooling sleeve 1030, a plurality of first support structures 1033 are provided between the first outer tube 1031 and the first inner tube 1032, and a plurality of second support structures 1034 are provided between the first inner tube 1032 and the ablation optical fiber 1104. The assembly structure of the second cooling sleeve 1030 and the ablation optical fiber 1104 under this embodiment can be found in the applicant's prior patent application "A Laser Ablation Assembly and Laser Ablation System" (application number: 202123422382.1), the entire contents of which are incorporated herein by reference.

[0111] The first channel and the second channel can be formed in the second cooling jacket 1030 in the following manner: Figure 6 As shown, the second cooling sleeve 1030 includes a first outer tube 1031 and a support member 1035. The ablation optical fiber 1104 is located in the middle of the lumen of the first outer tube 1031. Both sides are sealed and connected to the inner wall of the first outer tube 1031 through the support member 1035. The ablation optical fiber 1104 and the support member 1035 together separate the second cooling sleeve 1030 into a first channel 105 and a second channel 106. The first channel 105 and the second channel 106 are connected at a distal position to form a cooling circuit.

[0112] The first channel and the second channel can be formed in the second cooling jacket 1030 in the following manner: Figure 7 As shown, the second cooling sleeve 1030 only includes the first outer tube 1031, and the first outer tube 1031 is an elliptical tube. The short axis distance of the elliptical tube is consistent with the outer diameter of the ablation optical fiber. The ablation optical fiber is arranged inside the elliptical tube, and the outer wall of the ablation optical fiber is fitted with the inner wall of the elliptical tube in the short axis direction, so that the ablation optical fiber forms a first channel 105 and a second channel 106 on both sides of the long axis direction of the elliptical tube respectively.

[0113] The first channel and the second channel can also be formed in the second cooling jacket 1030 in the following manner: Fig.15 As shown, the second cooling sleeve 1030 is composed of a second outer tube 103 and a second inner tube 102. The second inner tube 102 is an annular tube. The ablation optical fiber 1104 is arranged in the annular tube cavity of the annular tube. The circular cavity inside the annular tube forms a first channel 105. The inner wall of the second outer tube 103 and the outer wall of the annular tube form a second channel 106.

[0114] It should be noted that this embodiment is not limited to the above four implementations. It can be understood that as long as the second cooling sleeve 1030 and the ablation optical fiber 1104 together form the first channel and the second channel for the circulation of the cooling medium, the implementation should fall within the protection scope of this application.

[0115] In order to realize the circulation of cooling medium and improve the support and protection of the second cooling sleeve 1030 and the ablation optical fiber 1104, in this embodiment, the optical fiber assembly also includes a cooling medium inlet and outlet assembly installed on the outside of the second cooling sleeve 1030 for connecting the cooling medium source and the cooling circuit, and a screw-tight anti-leakage plug 1202 installed on the proximal side of the cooling medium inlet and outlet assembly and sealed with the ablation optical fiber.

[0116] In one embodiment, Figure 4 As shown, the cooling medium inlet and outlet assembly includes a cooling medium inlet member 12031 and a cooling medium outlet member 12032, which are installed side by side on the second cooling jacket 1030, and one of the two members is communicated with the first channel 105 in the second cooling jacket 1030, and the other of the two members is communicated with the second channel 106 in the second cooling jacket 1030. The positions of the cooling medium inlet member 12031 and the cooling medium outlet member 12032 can be interchanged, and there is no limitation on this.

[0117] The cooling medium inlet member 12031 and the cooling medium outlet member 12032 may also be integrated.

[0118] In order to prevent leakage of the cooling medium, a screw-on leak-proof plug 1202 is provided at the proximal side of the cooling medium inlet and outlet assembly, and the screw-on leak-proof plug 1202 is installed on the second cooling sleeve 1030 and is sealed to the inner wall of the second cooling sleeve 1030. A sealing hole is reserved inside the screw-on leak-proof plug 1202 for the ablation optical fiber 1104 to pass through, and the sealing hole and the ablation optical fiber 1104 are also sealed.

[0119] Furthermore, if Figure 4 As shown, the sleeve assembly further includes a first sheath 1201 and a second sheath 1204. The first sheath 1201 is sleeved on the outside of the ablation optical fiber 1104 and one end of the first sheath 1201 is fixedly connected to the proximal side of the cooling medium inlet and outlet assembly, and the other end extends to the proximal end of the ablation optical fiber 1104; the second sheath 1204 is sleeved on the outside of the second cooling sleeve and one end of the second sheath 1201 is fixedly connected to the cooling medium inlet and outlet assembly, and the other end extends to the distal end of the second cooling sleeve 1030.

[0120] In order to protect the ablation optical fiber and the second cooling sleeve, the first sheath 1201 and the second sheath 1204 are configured to be incompressible in the longitudinal direction.

[0121] Furthermore, the first sheath 1201, the cooling medium inlet and outlet assembly and the second sheath 1204 form an integral rigid structure. In this embodiment, the rigid structure is fixedly connected to the catheter guide structure. The rigid structure can resist the longitudinal compression force when controlling the longitudinal movement of the ablation optical fiber, thereby ensuring the accuracy of the longitudinal control of the ablation optical fiber.

[0122] As an alternative embodiment, the sleeve member may include only the first sleeve 1201. When only the first sleeve 1201 is included, the proximal side of the first sleeve extends to the proximal fixed structure and is fixedly connected to the proximal fixed structure, and the first sleeve and the cooling medium inlet and outlet assembly form an integrated rigid structure.

[0123] As an alternative embodiment, the sleeve assembly may only include the second sheath 1204. When only the second sheath 1204 is included, the distal side of the second sheath may selectively extend to the catheter guide structure and be fixedly connected to the catheter guide structure, and the cooling medium inlet and outlet assembly, the catheter guide structure and the second sheath form an integral rigid structure.

[0124] In this embodiment, the cooling medium may be cooling water, liquid nitrogen, liquid carbon dioxide, etc. Of course, the cooling medium is not limited to liquid, and in other embodiments, the cooling medium may also be a gaseous cooling medium.

[0125] To facilitate the operator's operation or to be used in conjunction with other instruments, such as Figure 2 As shown, the ablation optical fiber 1104 assembly also includes an operating portion 1101 fixedly connected to the proximal end of the ablation optical fiber 1104, which is used for manual operation by an operator and / or assembly with other instruments. The operating portion 1101 can be a pull ring 1110 provided at the proximal end of the ablation optical fiber 1104, or an operating handle fixedly sleeved on the proximal end of the ablation optical fiber 1104 for the convenience of the operator to hold. This application does not impose any special restrictions on this, as long as it can facilitate the operation of the operator. The operating portion 1101 can also be used as a structure for assembly with other instruments, such as a progressive / rotating device, and the automation of the operation of the ablation optical fiber 1104 is achieved by assembly with the progressive / rotating device. For example, connectors of models such as 905, FC, ST or E2000 can be selected.

[0126] In laser interstitial thermal therapy, the patient's head (skull 1109) is located at the core position of the magnetic resonance during the treatment process, and the operator needs to lean in to operate, which is very inconvenient. In order to solve this problem, the ablation fiber 1104 and the second cooling sleeve 1030 of this embodiment can be extended a long distance to the proximal side, thereby creating an operating space for the operator. Considering that the operator is still exposed to radiation in the MR operating room, in order to protect the operator, the ablation fiber 1104 and the second cooling sleeve 1030 of this embodiment can be further extended on the proximal side to pass through the wall of the MR operating room and extend to the fiber control room on the side, so that the operator can get rid of the constraints of the MR operating room and remotely control the ablation fiber 1104 in the fiber control room to complete the treatment.

[0127] like Figures 8 to 10 An example of remotely controlling the movement of the ablation optical fiber 1104 is shown. It is well known that the MRI room needs a closed environment to ensure safety during operation. When the ablation optical fiber 1104 needs to be moved to adjust the ablation position, the operator needs to frequently enter the MRI room to move the ablation optical fiber 1104, which seriously affects the efficiency of the operation. By extending the cannula 201 to the optical fiber control room beside the MRI (of course, it can also be not beside the side, or even farther), and by controlling the movement of the ablation optical fiber 1104 in the optical fiber control room, the operation efficiency is improved.

[0128] In the fiber optic control room, the control of fiber optic movement can be manual or electric. Fig. 9 In the example of remotely controlling the movement of the optical fiber, the proximal end of the optical fiber is connected to a driving device 1108, and the driving device 1108 is used to control the forward and backward movement and / or rotation of the optical fiber. Fig.10 In the example of remotely controlling the movement of the optical fiber, the proximal end of the optical fiber is connected to a manual operation unit 1101, and the doctor controls the forward and backward movement and / or rotation of the optical fiber by manually operating the manual operation unit 1101. In other embodiments, the two control modes can also exist simultaneously.

[0129] In order to support and protect the ablation optical fiber 1104 and the second cooling sleeve 1030, the first sheath 1201 also extends through the wall of the MR operating room to the fiber control room on the side. Considering that the ablation optical fiber 1104 is particularly long from the MR operating room to the fiber control room, and the anti-leak plug 1202 is tightly connected to the ablation optical fiber 1104, the operator has a certain friction when pulling the ablation optical fiber 1104. In order to prevent the first sheath 1201 from swinging randomly due to excessive length when pulling the ablation optical fiber 1104, which affects the progressive and rotation operations of the ablation optical fiber 1104, in this embodiment, the ablation optical fiber assembly also includes a proximal fixing structure arranged in the fiber control room for fixing the proximal part of the first sheath 1201, and the proximal side of the first sheath 1201 extends to the proximal fixing structure and is fixedly connected to the proximal fixing structure. Alternatively, the proximal end of the first sheath is manually fixed in the fiber control room, for example, the operator pinches the proximal end of the first sheath with his hand.

[0130] The ablation optical fiber assembly further includes a fixing clamp that can selectively fix the first sheath 1201 to the ablation optical fiber 1104. When the ablation optical fiber starts to work, the proximal end of the first sheath 1201 is fixed to the ablation optical fiber 1104 by the fixing clamp, which can prevent the ablation optical fiber 1104 from accidentally moving.

[0131] Corresponding to the first sheath 1201, the second sheath 1204 extends to the distal end of the second cooling sleeve 1030, extends to the nut 1301 or the self-tapping screw 13022 and is fixed to the nut 1301 or the self-tapping screw 13022. Since the distal end of the first sheath 1201 is fixedly connected to the cooling inlet and outlet assembly, the proximal end of the second sheath 1204 is fixedly connected to the cooling medium inlet and outlet assembly, and the distal end extends to the catheter guide structure and is fixedly connected to the catheter guide structure, the first sheath 1201, the cooling medium inlet and outlet assembly, the second sheath 1204 and the catheter guide structure together form a rigid member that supports and protects the second cooling sleeve 1030 and the ablation optical fiber 1104. And for the rigid member, the proximal fixed structure in the optical fiber control room and the distal nut 1301 or the self-tapping screw 13022 form two-point support for the rigid member, so that the ablation optical fiber 1104 can achieve precise conduction when advancing.

[0132] In addition, during laser interstitial thermal therapy, the ablation direction needs to be adjusted according to the shape of the lesion. In order to adjust the lateral light-emitting direction of the ablation optical fiber 1104, the operator needs to rotate the ablation optical fiber 1104; or, in order to increase the axial ablation range of the ablation optical fiber 1104 and adjust the lateral light-emitting direction at the same time, the operator needs to move the ablation optical fiber 1104 forward or backward and rotate the optical fiber. In the related art, in order to adjust the lateral light-emitting direction of the ablation optical fiber 1104, the operator rotates the ablation optical fiber while measuring with a protractor until the ablation optical fiber is rotated to a suitable position.

[0133] Regarding the adjustment of the lateral light emission direction of the ablation optical fiber 1104, the problems existing in the related technologies are: slow measurement (usually repeated rotation and measurement are required to reach the expected direction), inaccurate control, and low precision (error).

[0134] In this embodiment, the position indicating portion further includes a second scale with an angle scale, and the position matching portion includes a second mark for matching the angle. Figure 3 As shown, the second ruler is a face plate 1106 fixedly connected to the outside of the sleeve and extending in the radial direction of the sleeve, and the angle scale is set on the face plate 1106; the second mark is an angle pointer 1107 fixedly connected to the optical fiber. The clockwise rotation angle and counterclockwise rotation angle of the ablation optical fiber 1104 relative to the sleeve can be identified by the indication of the angle pointer 1107 and the angle scale. Similar to the first ruler 1102 and the first mark 11051, the second ruler and the second mark can also be interchanged, as long as they can clearly and accurately reflect the relative rotation relationship between the ablation optical fiber 1104 and the sleeve, it is allowed in this application.

[0135] During use, the operator can quickly and accurately rotate the ablation optical fiber 1104 to a preset angle by means of the relative position relationship between the angle scale on the face plate 1106 and the angle pointer 1107 .

[0136] In order to more clearly indicate the relative rotation angle relationship between the ablation optical fiber 1104 and the sleeve assembly, a second scale with an angle scale is arranged on the outer periphery of the face plate 1106, and the angle pointer 1107 is arranged as an L-shaped pointer, one edge of which is overlapped on the outer periphery of the face plate 1106 with a length exceeding the face plate 1106, so that when the ablation optical fiber 1104 and the sleeve assembly rotate relative to each other, the L-shaped pointer and the angle scale on the face plate 1106 form a more intuitive correspondence.

[0137] In this embodiment, if Figure 5-7As shown, the ablation optical fiber 1104 can be a directional light-emitting optical fiber, which is a single-fiber structure. When performing conformal ablation, the operator needs to accurately control the forward movement, backward movement, and rotation of the directional light-emitting optical fiber to complete conformal ablation of the lesion.

[0138] The ablation optical fiber 1104 of this embodiment may also be a composite optical fiber structure including multiple independent optical fibers. By adopting the composite optical fiber structure, multi-directional light ablation can be achieved, so that the operator can complete the conformal ablation of the lesion without performing rotation control.

[0139] Specifically, Fig.11 As shown, this embodiment provides an ablation optical fiber, which includes:

[0140] The optical fiber bundle 1 comprises a plurality of independent optical fibers 101, wherein the plurality of independent optical fibers 101 are distributed along the circumferential direction to form a circumferential optical fiber;

[0141] An optical path adjustment structure 7, used for changing the propagation direction of the laser beam propagated or emitted by the independent optical fiber 101, so that the laser beam is output toward the radial outer side surface of the ablation optical fiber;

[0142] The laser energy in the independent optical fibers 101 is configured to be controllable individually or in groups, so that various forms of laser distribution can be formed.

[0143] In this embodiment, the optical fiber bundle 1 is a multi-channel ablation optical fiber composed of multiple optical fibers. Multiple independent optical fibers 101 are distributed circumferentially along the central axis of the light bundle 1 to form a circumferential optical fiber. They can be distributed circumferentially to form a complete ring, or they can be distributed circumferentially to form a non-closed ring with a certain curvature. Adjacent independent optical fibers 101 can fit tightly together so that as many independent optical fibers 101 as possible can be arranged on the same circumference. Of course, according to actual needs, adjacent independent optical fibers 101 can have a certain spacing between them. When multiple independent optical fibers 101 are distributed in a form with a certain spacing, multiple independent optical fibers 101 can be evenly distributed, asymmetrically distributed, or unevenly distributed, so as to facilitate the adjustment of the laser distribution form formed by multiple independent optical fibers 101.

[0144] The function of the optical path adjustment structure in this embodiment is to change the optical path of the laser light propagated or emitted by the independent optical fiber 101 (such as Fig.18 and Fig.19 The two optical path adjustment structures reflect the laser light, so that the laser light is output along the radial outer side of the independent optical fiber 101. In this embodiment, the optical path adjustment structure 7 has the function of changing the optical path, which can be achieved by an optical path reflection component, an optical path refraction component, or an optical path diffraction component. Multiple independent optical fibers 101 can correspond to one optical path adjustment structure 7 (such as Fig.18As shown), multiple independent optical fibers 101 may correspond to the same optical path adjustment structure 7 (as shown Fig.19 shown).

[0145] like Fig.13 and Fig.14 As shown, the light output range 2 output by each independent optical fiber 101 is a cone, and the light output range 2 gradually increases in the direction away from the independent optical fiber 101. Under the action of the optical path adjustment structure, the laser of each independent optical fiber 101 in this embodiment is output radially and toward the outer side of the ablation optical fiber, and the light output ranges 2 of adjacent independent optical fibers 101 may not overlap or not completely overlap.

[0146] like Fig.11 and Fig.12 As shown, when the laser output energy in each independent optical fiber 101 is consistent, the multiple independent optical fibers 101 distributed along the circumferential direction can jointly output a roughly annular or fan-shaped laser distribution. In order to be applicable to more ablation situations, the independent optical fibers 101 are preferably distributed in an annular shape, so that an annular laser distribution can be formed when the laser output energy is consistent. In this embodiment, for continuous laser, controlling the laser energy is actually controlling the laser power, and for pulsed laser, it is controlling the laser energy.

[0147] In order to make the laser distribution formed by multiple independent optical fibers 101 change with the shape of the lesion, in this embodiment, the laser energy of the independent optical fiber 101 is set to be individually controlled, or the multiple independent optical fibers 101 are divided into multiple groups according to certain rules, and the laser energy of each group of independent optical fibers 101 is set to be individually controlled, so that the laser energy of independent optical fibers 101 at different positions can be adjusted, and finally the laser distribution formed by multiple independent optical fibers 101 can match the lesion. In order to improve the matching degree between the laser distribution and the shape of the lesion, it is preferred to set the laser energy of each independent optical fiber 101 to be individually controllable.

[0148] When the laser energy in the independent optical fiber 101 is adjusted, the emission angle of the laser output by the independent optical fiber 101 remains unchanged, but the lateral ablation depth is changed. Fig.10 and Fig.11 As shown, when the lesion shape is circular, the laser output energy in each independent optical fiber 101 can be controlled to be consistent, thereby forming a ring-shaped laser distribution. Or when the lesion shape is fan-shaped, the laser energy in a part of the independent optical fibers 101 can be controlled to be zero, and the laser energy in another part of the independent optical fibers 101 can be consistent, thereby forming a fan-shaped laser distribution, or a contralateral distribution or a unilateral directional laser distribution can be formed. Alternatively, by adjusting the laser energy in each independent optical fiber 101, a laser distribution as shown in FIG. Fig.11 The ablation cross section produced as shown in FIG. 1 is a heart-shaped laser distribution.

[0149] This embodiment can fit a laser distribution that is close to or matches the shape of the lesion by adjusting the laser energy in each independent optical fiber 101, so that the lesion position can be accurately ablated at one time. The matching accuracy between the laser distribution formed by the independent optical fiber 101 and the lesion position can be improved by adjusting the number of independent optical fibers 101 and the light output range 2 output by each independent optical fiber 101. It can be understood that the more independent optical fibers 101 there are and the smaller the light output range 2 output by each independent optical fiber 101, the higher the accuracy of the fitting.

[0150] This embodiment can form a laser distribution pattern that matches the shape of the lesion through the ablation optical fiber, so that irregularly shaped diseased tissue can be accurately ablated at one time. Compared with a single-beam lateral optical fiber, the ablation time is short and multiple models are not required. In addition, the ablation range can be changed in real time by adjusting the laser energy in each independent optical fiber 101 during the operation, thereby solving the problems of long ablation time, inability to plan and conform to the lesion shape in real time, and difficulty in ablating irregularly shaped diseased tissue in the ablation optical fiber in related technologies.

[0151] When the light emitting ranges 2 of adjacent independent optical fibers 101 partially overlap or only touch each other in the circumferential direction, the entire optical fiber bundle 1 can form a light emitting range 2 that occupies at least one circumferential space. When the light emitting ranges 2 of adjacent independent optical fibers 101 do not touch each other, since the laser ablation process uses the heat of the laser to achieve ablation of the lesion, the heat of the laser can be transferred outward after contacting the lesion. Therefore, when the light emitting ranges 2 of adjacent independent optical fibers 101 do not touch each other, the heat transfer of the laser can still be used to ablate the lesion tissue between the adjacent light emitting ranges 2.

[0152] There are multiple arrangements of the multiple independent optical fibers 101 in the optical fiber bundle 1. One arrangement is that the multiple independent optical fibers 101 are distributed along the same circle, that is, the projection of the circumferential optical fiber formed by the multiple independent optical fibers 101 in the axial direction of the optical fiber bundle 1 is located on a circle. At this time, the optical fiber bundle 1 can form at least one annular laser distribution.

[0153] It is understandable that its projection may also be located on more circumferences, and when located on multiple circumferences, multiple circumferential optical fibers are distributed along the radial direction of the optical fiber bundle 1. Specifically, multiple independent optical fibers 101 are distributed to form 2 or more circles of circumferential optical fibers, and the outer circle of circumferential optical fibers are stacked on the inner circle of circumferential optical fibers.

[0154] More specifically, multiple circles of circumferential optical fibers are sequentially distributed from the inside to the outside along the radial direction of the optical fiber bundle 1. The number of independent optical fibers 101 contained in each group of circumferential optical fibers is not fixed and can be designed according to needs. In this arrangement, there are at least two different superposition modes of independent optical fibers 101. One superposition mode is that the independent optical fibers 101 of the outer circle and the independent optical fibers 101 of the inner circle are sequentially superimposed along the radial direction of the optical fiber bundle 1. Another superposition mode is that the independent optical fibers 101 of the outer circle are superimposed between the adjacent independent optical fibers 101 of the inner circle (such as Fig.15 As shown). It can be understood that the former has a low space utilization rate, which will lead to an increase in the diameter of the optical fiber bundle 1, while the latter can fully utilize the space and the diameter of the optical fiber bundle 1 can be controlled.

[0155] When the lateral light emitting positions on each independent optical fiber 101 are located at the same position in the axial direction, the length of the laser distribution formed as a whole is limited in the axial direction. When the axial length of the lesion position is greater than the axial length of the laser distribution, this type of ablation independent optical fiber 101 needs to be moved forward or backward multiple times in the axial direction for ablation. In order to reduce the number of movements of the ablation independent optical fiber 101 in this case, the axial length of the laser distribution of the optical fiber bundle 1 can be increased, that is, the optical fiber bundle 1 has multiple lateral light emitting positions in the axial direction, and the lateral light emitting positions are determined by the position of the optical path adjustment structure and the position of the optical fiber distribution. Therefore, it is necessary to adjust the axial position of the optical path adjustment structure and set the distribution of the axial optical fiber to make the optical fiber bundle 1 have multiple laser light emitting positions in the axial direction, so that multiple laser distributions can be formed at different axial positions of the ablation optical fiber, thereby achieving a wider range of conformal ablation.

[0156] When the projections of the circumferential optical fibers in the axial direction of the optical fiber bundle are located on the same circumference, in order to achieve the above purpose, the present embodiment divides the circumferential optical fibers into two or more circumferential optical fiber groups according to their lateral light-emitting positions in the axial direction. The lateral light-emitting positions corresponding to the circumferential optical fibers in the same circumferential optical fiber group are located at the same axial position, and the lateral light-emitting positions corresponding to the circumferential optical fibers in different circumferential optical fiber groups are located at different axial positions.

[0157] For example, the independent optical fibers 101 with an odd distribution order in the circumferential direction are divided into one circumferential optical fiber group, and the independent optical fibers 101 with an even distribution order in the circumferential direction are divided into another circumferential optical fiber group. The optical path adjustment structure 7 corresponding to the circumferential optical fiber group composed of the independent optical fibers 101 with an odd distribution order is controlled to be located near the front end, so that the lateral light output position is located near the front end position of the axial direction of the independent optical fiber 101. This type of circumferential optical fiber can form an annular laser distribution in the same circumferential space at the front end of the optical fiber bundle 1. The optical path adjustment structure 7 corresponding to the circumferential optical fiber group composed of the independent optical fibers 101 with an even distribution order is controlled to be located at a relatively rearward position, so that the lateral light output position is located relatively rearward in the axial direction. This type of circumferential optical fiber can form an annular laser distribution in the same circumferential space relatively rearward of the optical fiber bundle 1, and then the optical fiber bundle 1 can form two annular laser distributions. Similarly, three or more laser distribution forms can be formed according to other grouping rules of the circumferential optical fiber groups.

[0158] When the projection of the circumferential optical fiber on the axial direction of the optical fiber bundle 1 is located on two or more circumferences, in order to achieve the above purpose, the circumferential optical fiber is also divided into a plurality of circumferential optical fiber groups, and the axial positions of the lateral light output positions corresponding to the different circumferential optical fiber groups are adjusted. Fig.13 and Fig.14 As shown, the circumferential optical fibers of the inner circle are divided into one circumferential optical fiber group, and the circumferential optical fibers of the outer circle are divided into another circumferential optical fiber group. The optical path adjustment structure 7 corresponding to the circumferential optical fiber group located in the inner circle is located relatively close to the front end, and the optical path adjustment structure 7 corresponding to the circumferential optical fiber group located in the outer circle is located relatively close to the rear end, so that two annular laser distributions can be formed. Similarly, when more circumferential optical fibers are arranged, more laser distribution forms can be formed. It can be understood that the above two grouping forms of circumferential optical fiber groups can be combined with each other, that is, in the second grouping form, the circumferential optical fibers projected on the same circumference can also be divided into different circumferential optical fiber groups according to the set rules.

[0159] In addition, the independent optical fibers 101 also have a variety of grouping methods. The above embodiments only describe some of the grouping methods. It can be understood that the independent optical fibers 101 can also be grouped according to other rules (for example, adjusting the length of the independent optical fibers 101 so that the longer independent optical fibers 101 are in one group and the shorter independent optical fibers 101 are in another group, or grouping according to the superposition method of the independent optical fibers 101), and finally multiple laser distributions can be formed in the axial direction.

[0160] On the basis of having multiple laser distributions in the axial direction, in order to improve the coverage of the laser distribution of the optical fiber bundle 1 in the circumferential direction, such as Fig.13 and Fig.14In this embodiment, the light output ranges 2 of the independent optical fibers 101 in the adjacent circumferential optical fiber groups are staggered and do not completely overlap, that is, the two adjacent light output ranges 2 in the axial direction are staggered and do not completely overlap, so that the two light output ranges 2 can complement each other, thereby covering a larger circumferential range.

[0161] The ablation optical fiber also includes a central optical fiber 104 or an assembly structure arranged at the circumferential center of the optical fiber bundle 1, and the circumferential optical fibers are distributed around the central optical fiber 104 or the assembly structure. When set as the central optical fiber 104, the circumferential optical fibers are distributed around the central optical fiber 104, and the central optical fiber 104 can have the ability of independent ablation, and its laser output mode can be output forward along the axial direction.

[0162] When set as an assembly structure, the assembly structure can facilitate the installation and positioning of each independent optical fiber 101. Specifically, in order to achieve annular light emission, the light emission angle of each independent optical fiber 101 needs to meet the design requirements, so the independent optical fiber 101 is unique in the assembly position. For this purpose, a groove matching the independent optical fiber 101 can be opened on the assembly structure, and the independent optical fiber 101 can be partially accommodated in the groove, and the circumferential position of the independent optical fiber 101 is positioned by the groove. On this basis, it is also necessary to locate the light emission position of the independent optical fiber 101. For this purpose, in this embodiment, an indicator line can be marked on the assembly structure, and a corresponding indicator line can be marked on the independent optical fiber 101. The design position of the two indicator lines can be designed according to the requirement that when aligned, it indicates that the independent optical fiber 101 is in the design position.

[0163] The optical path adjustment structure 7 is used to change the laser emission direction in the independent optical fiber 101, and the optical path adjustment structure 7 can be arranged at the front end of the independent optical fiber 101. In one embodiment, the optical path adjustment structure 7 is configured as an optical path reflector, which has a reflective surface 71 for reflecting light. The reflective surface 71 has an angle greater than 0° with the axial direction of the optical fiber. The angle between the reflective surface 71 and the axial direction of the independent optical fiber 101 determines the laser emission angle of the independent optical fiber 101, so it can be designed according to needs, and the angle range is preferably 30°-60°. In this embodiment, the position of the reflective surface 71 in the axial direction will determine the lateral light emission position of the independent optical fiber 101.

[0164] To achieve the reflection of light, Fig.18As shown, the light path reflector in this embodiment can be set as a wedge-shaped structure 107 or a wedge-shaped structure 107 with a coating layer, and its reflection surface 71 is formed on the wedge-shaped structure 107. When only the wedge-shaped structure 107 is set, the light path reflector can be made of a total reflection material and form an integral structure with the independent optical fiber 101. The wedge-shaped structure 107 can be formed by grinding, cutting or etching the end face of the independent optical fiber 101. When the wedge-shaped structure 107 is a non-total reflection material, it is necessary to set a coating layer on the inner surface of the wedge-shaped structure 107, and the coating layer can be an optical coating. When this type of light path reflector is used, each independent optical fiber 101 is provided with an above-mentioned light path reflector. In other words, a reflection surface 71 is provided at the front end of each independent optical fiber 101. When the axial position of the reflection surface 71 in the independent optical fiber 101 changes, the lateral light output position of the independent optical fiber 101 changes accordingly.

[0165] When the optical fiber bundle 1 needs to form multiple laser distributions in the axial direction, the circumferential optical fibers can be divided into two or more circumferential optical fiber groups according to the axial position of the reflection surface 71. The reflection surfaces 71 corresponding to the circumferential optical fibers in the same circumferential optical fiber group are located at the same axial position, and the reflection surfaces 71 corresponding to the circumferential optical fibers in different circumferential optical fiber groups are located at different axial positions. For example, a group of circumferential optical fibers with the reflection surface 71 close to the front end will form a laser distribution at the front end of the optical fiber bundle 1, and another group of circumferential optical fibers with the reflection surface 71 relatively at the rear will form a laser distribution at a relatively rear position of the optical fiber bundle 1, thereby forming two laser distributions in the axial direction of the optical fiber bundle 1.

[0166] In another embodiment, if Fig.19 and Fig. 20 As shown, the light path reflector is configured as a reflective cone 108, and the reflective cone 108 is disposed in front of the independent optical fiber 101. It should be noted that the front of the independent optical fiber 101 refers to the direction in which the light in the independent optical fiber 101 advances, and when the reflective cone 108 is arranged, its reduced end is close to the independent optical fiber 101.

[0167] The reflection cone 108 can be a cone or a pyramid, and the reflection cone 108 also has a reflection surface 71 that can reflect the laser emitted by the independent optical fiber 101. Specifically, each side of the reflection cone 108 has a reflection surface 71, and the reflection surface 71 can correspond to one or more lateral light output positions. At the same time, the reflection surface 71 has multiple reflection positions in the axial direction. When it is used to form multiple laser distributions along the axial direction, multiple circumferential optical fibers can correspond to one reflection surface 71 together, and different reflection positions on the reflection surface 71 form lateral light output at different positions.

[0168] Specifically, when the optical fiber bundle 1 has circumferential optical fibers distributed along the inner and outer circles, a group of circumferential optical fibers located in the inner circle can realize lateral light emission through a reflection position relatively close to the tapered end on the reflection surface 71, and a group of circumferential optical fibers located in the outer circle can realize lateral light emission through a reflection position relatively far from the tapered end on the reflection surface 71. Finally, the laser distribution formed by the group of circumferential optical fibers located in the inner circle is relatively backward, and the laser distribution formed by the group of circumferential optical fibers located in the outer circle is relatively forward, so that at least two laser distributions distributed along the axial direction can also be formed through a reflection cone 108.

[0169] When the light path reflector is a reflective cone 108, the reflective cone 108 is located in front of the independent optical fiber 101 and has no direct connection with the independent optical fiber 101. Therefore, an additional structure is required to provide an installation base for the reflective cone 108, which can be a sleeve that is sleeved on the optical fiber bundle 1.

[0170] To facilitate the arrangement of multiple independent optical fibers 101, as Figures 16 to 19 As shown, the optical fiber bundle 1 composed of multiple independent optical fibers 101 is arranged in the second inner tube 102. According to different needs, the optical fiber bundle 1 can be located at different positions in the second inner tube 102. For example, in one embodiment, the optical fiber bundle 1 is embedded in the tube wall of the second inner tube 102. When making it, the independent optical fiber 101 can be clamped and fixed between the two walls, and then the two walls are curled to form a tube. In another embodiment, it can be done by injection molding, the independent optical fiber 101 is clamped in the mold, and then the fluid state tube material is injected, and the tube material is cooled and formed. Fig.16 As shown, another embodiment is to dispose the optical fiber bundle 1 in a hollow first channel 105 in the second inner tube 102 , and the first channel 105 is a hollow circular cavity in the second inner tube 102 .

[0171] Since the independent optical fiber 101 generates heat when in use, it is necessary to cool the independent optical fiber 101. Figures 16 to 19 As shown, the second outer tube 103 is sleeved on the second inner tube 102, and a second channel 106 is provided between the second outer tube 103 and the second inner tube 102. The first channel 105 and the second channel 106 are fluidically connected at the distal end to form a cooling circuit.

[0172] like Fig.16 and Fig.17As shown, in this embodiment, the second outer tube 103 is sleeved on the second inner tube 102, and there is a certain distance between the two to form a second channel 106. A retainer can be arranged on the outer side of the second inner tube 102, and the inner wall of the second outer tube 103 is connected to the retainer, and the retainer is used to stably form the second channel 106. After the second channel 106 is connected with the first channel 105 to form a cooling circuit, an external cooling medium can flow into the first channel 105 and flow through the second channel 106 before flowing out, or the external cooling medium can flow into the second channel 106 and flow through the first channel 105 before flowing out, so as to dissipate heat for the independent optical fiber 101. The external cooling medium can be a cooling liquid or a cooling gas.

[0173] When the optical fiber bundle 1 is arranged in the first channel 105 of the second inner tube 102, the size of the first channel 105 needs to meet the requirements of the arrangement of multiple independent optical fibers 101 and the smooth flow of the cooling medium, and the cooling medium can directly contact the independent optical fibers 101 when flowing in the cooling circuit. When the optical fiber bundle 1 is embedded in the tube wall of the second inner tube 102, the cooling medium will not directly contact the independent optical fibers 101 when flowing in the cooling circuit. Since the hollow first channel 105 in the second inner tube 102 does not need to be used to install the optical fiber bundle 1, but only needs to be used for the flow of the cooling medium, the diameter of the first channel 105 can be reduced, so that the diameters of the second inner tube 102 and the second outer tube 103 can be reduced, and the diameter of the ablated independent optical fibers 101 can be reduced. Fig.19 As shown, in the cooling structure, the second outer tube 103 can serve as a mounting base for the reflection cone 108 .

[0174] like Fig.18 and Fig.19 As shown, in order to enable the laser to penetrate the second cooling sleeve 104, the second cooling sleeve 104 in this embodiment is made of a transparent material, the front end of the second cooling sleeve 104 is a closed structure, and the area between the front end of the second cooling sleeve 104 and the second inner tube 102 can be used as a reflux section of the cooling medium, and the reflux section connects the first channel of the second inner tube 102 and the second channel of the second cooling sleeve 104.

[0175] Example 3

[0176] According to another aspect of the present application, Fig.21 and Fig. 22 As shown, a laser interstitial thermal therapy system is provided, including an ablation optical fiber and a laser generating component. The laser generating component is connected to an independent optical fiber 101 and is used to output laser into each independent optical fiber 101. The laser generating component can adjust the laser energy in the independent optical fiber 101, so that the optical fiber bundle 1 with multiple independent optical fibers 101 can form various forms of laser distribution.

[0177] In one embodiment, the laser generating assembly includes a plurality of lasers 3, and the plurality of lasers 3 are connected to the corresponding independent optical fibers 101 through a connector 4. The connector 4 is an MPO connector, which has a plurality of access ports and an access port, wherein the plurality of access ports are respectively connected to a laser 3, and the plurality of access ports can be respectively connected to an independent optical fiber 101, and the output power of each laser 3 can be independently controlled, thereby controlling the laser energy in each independent optical fiber 101.

[0178] In another embodiment, the laser generating assembly includes a laser 3, an optical splitter 5, and a plurality of variable optical attenuators 6;

[0179] The laser 3 is connected to the optical splitter 5, and the laser output by the laser 3 is divided into N parts by the optical splitter 5. Each output port of the optical splitter 5 is connected to a variable optical attenuator 6. The multiple variable optical attenuators 6 are connected to the corresponding independent optical fibers 101 one by one. By adjusting the optical attenuation coefficients of different variable optical attenuators 6, laser outputs of different powers in different independent optical fibers 101 can be achieved.

[0180] Example 4

[0181] This embodiment provides an ablation fiber assembly for laser interstitial thermal therapy, which includes an ablation fiber 1104 and a sleeve member. In this embodiment, the difference between the ablation fiber and the ablation fiber in embodiments 1 to 3 is that the ablation fiber 1104 includes an ablation fiber body and a first cooling sleeve (not shown in the figure) connected thereto. Specifically, the first cooling sleeve can be fixedly sleeved on the ablation fiber body by bonding, tight fitting or using a locking member, so that the ablation fiber and the first cooling sleeve are an integrally connected structure. The sleeve member is sleeved on the outside of the integral structure formed by the ablation fiber body and the first cooling sleeve, and the integral structure is movable relative to the sleeve member.

[0182] In some embodiments, the first ruler or the first mark is set on the ablation optical fiber body, and the matching first mark or the first ruler is set on the sleeve; in other embodiments, the first ruler or the first mark is set on the first cooling sleeve, and the matching first mark or the first ruler is set on the sleeve.

[0183] Further, based on the above, in some embodiments, the first scale or the first mark is set on the inner tube of the first cooling sleeve; in other embodiments, the first scale or the first mark is set on the outer tube of the first cooling sleeve. The first cooling sleeve is used to cool the ablation optical fiber body.

[0184] In some embodiments, the specific structure of the first cooling sleeve and the assembly structure of the first cooling sleeve and the ablation optical fiber body are the same as the specific structure of the second cooling sleeve and the assembly structure of the second cooling sleeve and the ablation optical fiber in the above-mentioned embodiment, with the difference that, in the present embodiment, the first cooling sleeve and the ablation optical fiber body are fixedly assembled.

[0185] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection created by this application.

Claims

1. A slender surgical instrument, characterized in that: The invention comprises a slender member, which is used to cooperate with a sleeve member sleeved on the outside thereof and can move relative to the sleeve member when in use, one of the slender member and the sleeve member is provided with a position indicating portion, and the other is provided with a position matching portion, and the relative position change between the position indicating portion and the position matching portion is used to indicate the relative motion position relationship between the slender member and the sleeve member, and the relative motion position relationship includes a relative movement distance and / or a relative rotation angle.

2. The elongated surgical instrument according to claim 1, characterized in that: The position indicating portion includes a first ruler provided with a length scale and / or a second ruler provided with an angle scale, and the position matching portion includes a first mark for matching with the length scale and / or a second mark for matching with the angle scale; The relative position change between the first scale and the first mark is used to indicate the relative movement distance between the elongated member and the sleeve member, and the relative position change between the second scale and the second mark is used to indicate the relative rotation angle between the elongated member and the sleeve member.

3. The elongated surgical instrument according to claim 2, characterized in that: The first scale is a wrapping layer fixedly connected to the outside of the slender member and extending axially along the slender member, the length scale is provided on the wrapping layer, and the first mark is a marking line provided on the sleeve member or the periphery of the proximal end of the sleeve member; and / or, The second scale is a dial fixedly connected to the outer side of the sleeve and extending in the radial direction of the sleeve, the angle scale is arranged on the dial, and the second mark is an angle pointer fixedly connected to the elongated member.

4. The elongated surgical instrument according to any one of claims 1 to 3, characterized in that: It also includes an operating portion fixedly connected to the proximal end of the slender member and used for manual operation by an operator and / or assembly with an instrument.

5. The elongated surgical instrument according to any one of claims 1 to 3, characterized in that: The slender component is one of an ablation optical fiber, a deep electrode, a liquid nitrogen catheter, a water vapor injection catheter, and a radio frequency probe.

6. An ablation optical fiber assembly for laser interstitial thermal therapy, characterized in that: include: Ablation fiber; a sleeve member, which is sleeved on the outside of the ablation optical fiber when in use, and the ablation optical fiber and the sleeve member can move relative to each other along the long axis, and the lumen of the sleeve member is used to construct an implantation channel for the ablation optical fiber to be implanted into the target tissue; One of the ablation optical fiber and the sleeve is provided with a position indicating portion, and the other is provided with a position matching portion. The relative position change between the position indicating portion and the position matching portion along the long axis is used to indicate the relative movement distance between the ablation optical fiber and the sleeve along the long axis.

7. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 6, characterized in that: The position indicating portion includes a first scale having a length scale, and the position matching portion includes a first mark for matching with the length scale.

8. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 7, characterized in that: The first ruler is a wrapping layer fixedly connected to the outside of the ablation optical fiber and extending along the long axis direction of the ablation optical fiber. The length scale is arranged on the wrapping layer. The first mark is a marking line arranged on the sleeve or the periphery of the proximal end of the sleeve.

9. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 7, characterized in that: The ablation optical fiber includes an ablation optical fiber body and a first cooling sleeve connected thereto, and the first scale or first mark is arranged on the ablation optical fiber body or the first cooling sleeve.

10. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 6, characterized in that: The sleeve member includes a catheter, which is used to receive the ablation optical fiber therein and the ablation optical fiber can move relative to the catheter along the long axis direction; the ablation optical fiber assembly also includes a catheter guide structure for fixing the catheter relative to the target object.

11. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 10, characterized in that: The catheter guide structure includes a guide member and a fastener, wherein the guide member is used to be fixed to the target object, a guide channel is provided inside the guide member, and after the guide member is fixed to the target object, the guide channel enables the inside of the target object to communicate with the outside, and the catheter is set in the guide channel and locked with the guide member by the fastener.

12. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 11, characterized in that: The guide member includes a self-tapping threaded member, the guide channel is provided inside the self-tapping threaded member, and the self-tapping threaded member is used to be screwed onto a pre-drilled hole in the skull of the target object; the fastener includes a nut for locking the catheter to the self-tapping threaded member.

13. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 10, characterized in that: The catheter guiding structure is arranged at the end of the mechanical arm of the surgical robot.

14. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 10, characterized in that: The catheter is a second cooling sleeve, a first channel and a second channel are formed inside the second cooling sleeve, and the first channel and the second channel are connected at the distal end to form a cooling circuit for circulation of a cooling medium.

15. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 14, characterized in that: The second cooling sleeve also includes a cooling medium inlet and outlet assembly for connecting a cooling medium source and the cooling circuit, and a screw-on leak-proof plug installed on the proximal end of the cooling medium inlet and outlet assembly and sealed with the ablation optical fiber.

16. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 15, characterized in that: The sleeve assembly also includes a first sheath and / or a second sheath, the first sheath is sleeved on the outside of the ablation optical fiber and one end is fixedly connected to the proximal side of the cooling medium inlet and outlet assembly, and the other end extends to the proximal end of the ablation optical fiber, the second sheath is sleeved on the outside of the second cooling sleeve and one end is fixedly connected to the cooling medium inlet and outlet assembly, and the other end extends to the distal end of the second cooling sleeve.

17. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 16, characterized in that: A position matching portion is provided at the proximal end of the first sheath.

18. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 16, characterized in that: The first sheath and / or the second sheath are configured to be incompressible in the longitudinal direction.

19. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 18, characterized in that: When the sleeve member includes a first jacket, the first jacket and the cooling medium inlet and outlet assembly form an integral rigid structure; or, When the sleeve member includes a second sheath, one side of the distal end of the second sheath can be selectively extended to the catheter guide structure and fixedly connected to the catheter guide structure, and the cooling medium inlet and outlet assembly, the catheter guide structure and the second sheath form an integral rigid structure; or, When the sleeve assembly includes a first sheath and a second sheath, a distal end of the second sheath can selectively extend to the catheter guide structure and be fixedly connected to the catheter guide structure, and the first sheath, the cooling medium inlet and outlet assembly, the catheter guide structure, and the second sheath form an integral rigid structure.

20. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 19, characterized in that: The ablation optical fiber assembly further includes a proximal fixing structure for fixing the proximal portion of the first sheath, and a proximal side of the first sheath extends to the proximal fixing structure and is fixedly connected to the proximal fixing structure.

21. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 19, characterized in that: When the ablation fiber assembly is used with the assistance of MRI, the ablation fiber and the proximal end of the first sheath extend over a long distance to a fiber control room next to the MRI room, so that the ablation fiber can be remotely controlled in the fiber control room.

22. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 16, characterized in that: The ablation optical fiber assembly further includes a fixing clamp capable of selectively fixing the first sheath to the ablation optical fiber.

23. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 6, characterized in that: The proximal end of the ablation optical fiber is connected to a driving device for controlling the ablation optical fiber or a control unit for manual control by an operator.

24. The ablation optical fiber assembly for laser interstitial thermal therapy according to any one of claims 6 to 23, characterized in that: The position indicating portion further includes a second ruler having an angle scale, and the position matching portion further includes a second mark for matching with the angle scale, and the relative position change between the second ruler and the second mark is used to indicate the relative rotation angle between the optical fiber assembly and the sleeve assembly.

25. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 24, characterized in that: The second scale is a face plate fixedly connected to the outside of the sleeve and extending radially along the sleeve, the angle scale is arranged on the face plate, and the second mark is an angle pointer fixedly connected to the ablation optical fiber and pointing to the angle scale.

26. The ablation optical fiber assembly for laser interstitial thermal therapy according to claim 6, characterized in that: The ablation optical fiber includes an optical fiber bundle and an optical path adjustment structure, the optical fiber bundle includes multiple independent optical fibers; the multiple independent optical fibers are distributed circumferentially to form a circumferential optical fiber; the optical path adjustment structure is used to change the direction of the laser propagated or emitted by the multiple independent optical fibers so that the laser is output toward the radial outer side of the ablation optical fiber; the laser energy in the independent optical fibers is configured to be controllable individually or in groups, so that various forms of laser distribution can be formed.

27. A laser interstitial thermal therapy system, characterized in that: It comprises an ablation optical fiber assembly for laser interstitial thermal therapy according to any one of claims 6 to 26, and a laser generating assembly connected to the ablation optical fiber assembly.

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