Heating device for synthesizing fosfomycin levo-fosfomycin dextro-fosfomycin amine salt

Abstract

The utility model provides a heating device for synthesizing fosfomycin levofosfomycin amine salt, and particularly relates to the technical field of pharmaceutical production, the heating device comprises a plurality of monomer tanks with fan-shaped cross sections, the end parts of the monomer tanks are sealed by sealing plates, and the upper ends and the lower ends of the monomer tanks are respectively provided with inlets and outlets; the single tanks are annularly arranged at equal intervals, and an electric heating plate is arranged between every two adjacent single tanks. The electric heating plates are arranged between the single tanks, so that the heating distance between a heat source and materials is reduced, the heating area is increased, and the heating efficiency can be further improved.

Description

Technical Field

[0001] The utility model belongs to the technical field of pharmaceutical production, and particularly relates to a heating device for the synthesis of levofloxacin fosfomycin amide salt. Background Art

[0002] In the production of levofloxacin fosfomycin amide salt, a raw material heating process is required. Existing heating devices generally include a heating tank, and a heating jacket or heating rods are arranged outside the heating tank to heat the materials inside the tank. However, since the distance between the inside of the tank and the heat source is relatively far, the heating efficiency is slow, which in turn affects the heating efficiency.

[0003] In view of the above deficiencies, there is a need for a heating device for the synthesis of levofloxacin fosfomycin amide salt to improve the heating efficiency and thus improve the production efficiency. Summary of the Utility Model

[0004] The purpose of the utility model is to provide a heating device for the synthesis of levofloxacin fosfomycin amide salt to improve the heating efficiency and thus improve the production efficiency.

[0005] The utility model provides the following technical solutions:

[0006] A heating device for the synthesis of levofloxacin fosfomycin amide salt includes a number of monomer tanks with a fan-shaped cross-section. The ends of the monomer tanks are closed by a sealing plate, and an inlet and an outlet are respectively provided at the upper and lower ends of the monomer tanks. The monomer tanks are arranged in an equidistant ring, and electric heating plates are provided between adjacent monomer tanks.

[0007] Preferably, adjacent monomer tanks are sequentially connected in series through a pipeline.

[0008] Preferably, the pipeline is located at the lower side of the monomer tank. The pipeline is in a cuboid shape as a whole, and the upper end surface of the pipeline supports the lower end of the electric heating plate.

[0009] Preferably, connecting plates are respectively provided at the top and bottom of the monomer tank, and the connecting plates firmly connect the monomer tanks.

[0010] Preferably, the firm connection is achieved by welding or flange connection.

[0011] Preferably, there are 4 monomer tanks in total. Two semi-circular pipes are provided at the upper end of the monomer tanks, and the two semi-circular pipes are arranged in a cross shape to penetrate the 4 monomer tanks. An inlet is provided at the center of the cross.

[0012] Preferably, an annular discharge pipe is provided at the lower end of the monomer tank. An outlet is provided outside the discharge pipe, and the inside of the discharge pipe penetrates the monomer tank through a connecting pipe.

[0013] Advantages of the Utility Model

[0014] By arranging electric heating plates between monomer tanks, this device reduces the heating distance between the heat source and the material and increases the heating area, thereby improving the heating efficiency. Brief Description of the Drawings

[0015] The drawings are used to provide a further understanding of the present invention and form a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation to the present invention. In the drawings:

[0016] Figure 1 is the overall view of the present invention;

[0017] Figure 2 is the structural decomposition view;

[0018] The reference numerals in the drawings are: 1, monomer tank; 2, sealing plate; 3, inlet; 4, outlet; 5, semi-circular tube; 6, discharge pipe; 7, connecting pipe; 8, pipeline; 9, electric heating plate; 10, connecting plate. Detailed Description of the Preferred Embodiments

[0019] As Figures 1 to 2 , a heating device for the synthesis of levofloxacin fosfomycin salt, comprising a plurality of monomer tanks 1 with a fan-shaped cross-section. The ends of the monomer tanks 1 are closed by sealing plates 2, and the sealing plates 2 and the monomer tanks 1 are connected by welding. Inlets 3 and outlets 4 are respectively provided at the upper and lower ends of the monomer tanks 1 for feeding and discharging materials; the monomer tanks 1 are arranged in an equidistant ring. Electric heating plates 9 are arranged between adjacent monomer tanks 1. The principle of the electric heating plates 9 is a known prior art and is described in detail in encyclopedias, and the specific principle structure will not be elaborated here. To ensure the stability of the electric heating plates 9, connection ears can also be provided at the edge parts of the electric heating plates 9. Bolts are welded to the sides of the monomer tanks 1, and then the connection ears and the bolts are fixed by nuts;

[0020] To ensure the uniformity and fluidity of heating between the single tanks 1, adjacent monomer tanks 1 are sequentially connected in series through pipelines 8. The pipelines 8 are located at the lower side parts of the monomer tanks 1, so as to ensure the interaction between the single tanks 1 as much as possible; the pipelines 8 and the single tanks 1 can be connected by welding or flanges.

[0021] The whole pipeline 1 is in a cuboid shape, and the upper end surface of the pipeline 8 supports the lower end of the electric heating plate 9, which can not only play a supporting role but also increase the flow area.

[0022] Preferably, connecting plates 10 are respectively provided at the tops and bottoms of the monomer tanks 1, and the connecting plates 10 stably connect the monomer tanks 1. The stable connection is achieved by welding or flanges, and preferably by flanges for easy disassembly;

[0023] In actual production, for the convenience of production, a total of 4 monomer tanks 1 are provided, which is convenient for layout and installation; two semi-circular pipes 5 are provided at the upper end of the monomer tank 1, and the two semi-circular pipes 5 are welded in a cross shape to penetrate the 4 monomer tanks 1. An inlet 3 is provided at the cross center. Through one inlet 3, the simultaneous feeding of the 4 monomer tanks can be achieved; and an annular discharge pipe 6 is provided at the lower end of the monomer tank 1, and an outlet 4 is provided on the outer side of the discharge pipe 6. The inside of the discharge pipe 6 penetrates the monomer tank 1 through a connecting pipe 7. In this way, the discharge of the 4 monomer tanks can be achieved through 1 outlet 4; in order to ensure the heat preservation effect, a sandwich can be provided outside the monomer tank 1, and the inside of the sandwich is air. Of course, inert gas can also be introduced to further improve the heat insulation effect.

[0024] The working mode of this device:

[0025] The material is sent into the 4 monomer tanks 1 through the semi-circular pipe 5 via the inlet 3, and heating is achieved through the electric heating plate 9. Since the electric heating plate 9 is arranged between the monomer tanks 1, the heating distance between the heat source and the material is reduced, and the heating area is increased. Therefore, the heating efficiency can be improved. After heating is completed, the material is discharged through the discharge pipe 6 via the outlet 4.

[0026] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. A heating device for the synthesis of levofloxacin fosfomycin salt, characterized in that: The single tank includes several cross-sectional sectors. The ends of the single tank are closed by sealing plates, and an inlet and an outlet are respectively provided at the upper and lower ends of the single tank. The single tanks are arranged in equidistant annular arrays, and electric heating plates are provided between adjacent single tanks.

2. The heating device for the synthesis of levofloxacin fosfomycin salt according to claim 1, characterized in that: Adjacent single tanks are sequentially connected in series through pipelines.

3. The heating device for the synthesis of levofloxacin fosfomycin salt according to claim 2, wherein: The pipeline is located at the lower side of the single tank. The whole pipeline is in the shape of a cuboid, and the upper end surface of the pipeline supports the lower end of the electric heating plate.

4. A heating device for the synthesis of levofloxacin fosfomycin trometamol according to claim 3, characterized in that: Connection plates are respectively provided at the top and bottom of the single tank, and the connection plates stably connect the single tanks.

5. A heating device for the synthesis of levofloxacin fosfomycin salt according to claim 4, characterized in that: The stable connection is achieved by welding or flange connection.

6. The heating device for synthesizing levofloxacin fosfomycin salt according to claim 1, wherein: There are 4 single tanks in total. Two semi-circular pipes are provided at the upper end of the single tank. The two semi-circular pipes are arranged in a cross shape to penetrate the 4 single tanks, and an inlet is provided at the cross center.

7. A heating device for the synthesis of levofloxacin fosfomycin salt according to claim 1, characterized in that: An annular discharge pipe is provided at the lower end of the single tank. An outlet is provided outside the discharge pipe, and the single tank is penetrated by a connecting pipe inside the discharge pipe.

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