Filtering device of polypeptide synthesis reactor

By designing a filtration device for a peptide synthesis reactor, and utilizing structures such as sliding strips, rubber strips, and locking rings, the filtration device can be flexibly installed and disassembled within the reactor. This solves the problem of the filtration device having a single application scenario and improves the reactor's operational flexibility and ease of cleaning.

CN223697086UActive Publication Date: 2025-12-23PURUIXIN BIOTECHNOLOGY (LISHUI) CO LTD
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Patent Information

Application Number
CN202520052988.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-10
Publication Date
2025-12-23
Estimated Expiration
2035-01-10

AI Technical Summary

Technical Problem

Existing filtration devices have a limited range of applications within the reactor and cannot be flexibly replaced with other equipment when not in use.

Method used

A filtration device for a peptide synthesis reactor was designed. The filtration device can be detachably installed at the bottom of the reactor through fixing and connecting devices. A stable connection is ensured by using structures such as sliding strips, rubber strips, damping rods and locking rings. The feeding and discharging are controlled by a solenoid valve.

Benefits of technology

It enables flexible installation and disassembly of the filter device inside the reactor, facilitating diverse use, improving the reactor's operational flexibility, and making it easy to clean the filter screen and filter cotton.

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Abstract

The utility model provides a filtering device of a polypeptide synthesis reactor, which relates to the technical field of filtering devices and comprises a connecting frame, a filter screen is fixedly connected to the inner wall of the connecting frame, filtering cotton is fixedly connected to the inner wall of the connecting frame, a feeding port is formed in the top of the connecting frame, and a discharging pipe is arranged at the bottom of the connecting frame. A first electromagnetic valve is arranged on the surface of the discharging pipe, a fixing device is arranged on the surface of the feeding port, a reaction kettle is arranged at the top of the feeding port, a supporting frame sleeves the surface of the reaction kettle, and when the fixing device is used, the feeding port is manually slid into the inner wall of the bottom of a connecting pipe, and then a sliding strip slides into a sliding groove; when the sliding strip completely slides into the sliding groove, the rubber strip is extruded to the bottom of the sliding strip, so that the sliding strip can be limited in the sliding groove through the rubber strip, and the filtering device can be arranged at the bottom of the reaction kettle when the filtering device needs to be used.
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Description

TECHNICAL FIELD

[0001] The utility model relates to filter device technical field especially relates to a polypeptide synthesis reactor filter device. BACKGROUND

[0002] The filter device is a kind of device for separating polypeptide-containing substances and solutions in polypeptide synthesis, when using filter device, the polypeptide synthesis material and solution are entered into the inside of connecting frame through feed inlet, the filter screen and filter cotton arranged in the inside of connecting frame can well separate solution and solid substance, so that polypeptide-containing substances are separated.

[0003] The inventor found that filter device still has at least the following problems in daily work: when using filter device, the polypeptide synthesis material and solution are entered into the inside of connecting frame through feed inlet, the filter screen and filter cotton arranged in the inside of connecting frame can well separate solution and solid substance, so that polypeptide-containing substances are separated, but in actual use process, because filter device is generally arranged at the bottom of the inner wall of reactor kettle, other reactor kettle needs to be used when filter device is not needed, so that the scene of reactor kettle is relatively single. UTILITARY MODEL

[0004] The utility model aims at solving the shortcomings in prior art and provides a polypeptide synthesis reactor filter device.

[0005] In order to achieve the above object, the utility model adopts the following technical scheme: a polypeptide synthesis reactor filter device, including connecting frame, the inner wall of connecting frame is fixedly connected with filter screen, the inner wall of connecting frame is fixedly connected with filter cotton, the top of connecting frame is provided with feed inlet, the bottom of connecting frame is provided with discharge pipe, the surface of discharge pipe is provided with first electromagnetic valve, the surface of feed inlet is provided with fixing device, the top of feed inlet is provided with reactor kettle, the surface of reactor kettle is sleeved with support frame, the top of reactor kettle is fixedly connected with motor, the output of motor is fixedly connected with stirring rod, the top of reactor kettle is provided with feed pipe, the bottom of reactor kettle is fixedly connected with connecting pipe, the surface of connecting pipe is provided with second electromagnetic valve, the surface of connecting frame is provided with connecting device, the fixing device includes sliding strip, the surface of sliding strip and feed inlet is fixedly connected, the inner wall of the bottom of connecting pipe is provided with sliding groove, the inner wall of sliding groove is slidably connected with sliding strip, the inner wall of sliding groove is fixedly connected with rubber strip.

[0006] The effect achieved by the above components is that when the fixing device is used, the feeding port is manually slid into the inner wall of the bottom of the connecting pipe, and then the sliding bar is slid into the sliding groove, and after the sliding bar is completely slid into the sliding groove, the rubber strip is pressed to the bottom of the sliding bar, so that the sliding bar is limited in the sliding groove by the rubber strip, and the filter device can be arranged at the bottom of the reaction kettle when the filter device is needed to be used, thereby realizing the diversity of the reaction kettle to a certain extent.

[0007] Preferably, a circular groove is arranged on the surface of the connecting pipe, the inner wall of the circular groove is sleeved with a semicircular ring, the bottom of the semicircular ring is fixedly connected with an L-shaped plate, and the end of the L-shaped plate away from the semicircular ring is arranged at the bottom of the sliding bar.

[0008] The effect achieved by the above components is that the semicircular ring is slid into the circular groove, and then the end of the L-shaped plate away from the semicircular ring is arranged at the bottom of the sliding bar, so that the sliding bar can be well limited in the sliding groove.

[0009] Preferably, a first damping rod is uniformly fixedly connected to the inner wall of the circular groove, one end of the first damping rod away from the circular groove is fixedly connected to one side of the inner wall of the semicircular ring, a first spring is sleeved on the surface of the first damping rod, one end of the first spring is fixedly connected to one side of the inner wall of the circular groove, and the end of the first spring close to the first damping rod is fixedly connected to one side of the semicircular ring.

[0010] The effect achieved by the above components is that the semicircular ring is pulled towards the direction close to the circular groove by the first spring, so that the semicircular ring can be well arranged in the circular groove, and then the end of the L-shaped plate is arranged at the bottom of the sliding bar.

[0011] Preferably, a clamping ring is slidably sleeved on the surface of the connecting pipe, the clamping ring is slidably sleeved on the surface of the L-shaped plate, rubber blocks are uniformly fixedly connected to the surface of the L-shaped plate, and the two rubber blocks are arranged on the two sides of the clamping ring respectively.

[0012] The effect achieved by the above components is that the clamping ring is manually sleeved on the surface of the connecting pipe and the L-shaped plate, and then the clamping ring is limited in the middle of the two rubber blocks, so that the clamping ring can be well limited on the surface of the L-shaped plate by the rubber blocks.

[0013] Preferably, the connecting device comprises a first connecting block and a second connecting block, a positioning groove is arranged in the inner wall of the first connecting block, a connecting ring is fixedly connected to the inner wall of the second connecting block, a rubber ring is fixedly connected to one side of the connecting ring, and the rubber ring is arranged in the positioning groove.

[0014] The effects achieved by the components are that when the connecting device is used, the connecting ring is manually slid to the inner wall of the first connecting block, and the rubber ring is further pressed into the positioning groove, so that the first connecting block and the second connecting block can be well arranged together, and reverse operation facilitates disassembly of the connecting frame, and further facilitates cleaning of the filter screen and the filter cotton inside the connecting frame.

[0015] Preferably, a fixing groove is arranged at the bottom of the first connecting block, and a fixing ring is slidably connected to the inner wall of the fixing groove, and the end of the fixing ring away from the fixing groove is fixedly connected to the top of the second connecting block.

[0016] The effects achieved by the components are that the fixing ring is slid into the fixing groove, so that the connection between the first connecting block and the second connecting block is more compact.

[0017] Preferably, a connecting frame is fixedly connected to the surface of the second connecting block, a round rod is rotatably inserted into the top of the connecting frame, a clamping plate is fixedly connected to the top of the round rod, and the clamping plate is arranged at the top of the first connecting block.

[0018] The effects achieved by the components are that the clamping plate is manually controlled to drive the round rod to rotate, and the clamping plate is arranged at the top of the first connecting block, so that the first connecting block and the second connecting block can be well limited together.

[0019] Preferably, a clamping block is fixedly connected to the top of the first connecting block, and two clamping blocks are arranged on the two sides of the clamping plate.

[0020] The effects achieved by the components are that the clamping block is made of rubber, the clamping plate is limited between the two clamping blocks, and the clamping plate is well limited at the top of the first connecting block.

[0021] In the utility model, the fixing device is arranged, when the fixing device is used, the feeding port is manually slid into the bottom inner wall of the connecting pipe, and the sliding strip is further slid into the sliding groove, after the sliding strip is completely slid into the sliding groove, the rubber strip is pressed to the bottom of the sliding strip, so that the sliding strip can be limited in the sliding groove by the rubber strip, so that the filtering device can be arranged at the bottom of the reaction kettle when the filtering device is needed to be used, and the diversity of the reaction kettle work is realized to a certain extent. BRIEF DESCRIPTION OF DRAWINGS

[0022] Figure 1 A three-dimensional structure schematic diagram of the polypeptide synthesis reactor filtering device is provided in the utility model;

[0023] Figure 2 A three-dimensional structure schematic diagram of the novel L-shaped plate is provided in the utility model;

[0024] Figure 3 The utility model provides a three-dimensional structure schematic diagram of novel clamping ring is proposed.

[0025] Figure 4 The utility model provides a three-dimensional structure schematic diagram of novel connecting frame is proposed.

[0026] Legend: 1, connecting frame; 2, filter screen; 3, filter cotton; 4, discharge pipe; 5, feed inlet; 6, first electromagnetic valve; 7, fixing device; 701, sliding strip; 702, sliding slot; 703, rubber strip; 704, round groove; 705, first damping rod; 706, first spring; 707, semicircle ring; 708, L-shaped plate; 709, clamping ring; 710, rubber block; 8, connecting device; 801, first connecting block; 802, second connecting block; 803, fixed groove; 804, fixed ring; 805, connecting ring; 806, rubber ring; 807, positioning groove; 808, connecting frame; 809, round rod; 810, clamping plate; 811, clamping block; 9, support frame; 10, reaction kettle; 11, motor; 12, stirring rod; 13, feed pipe; 14, connecting pipe; 15, second electromagnetic valve. DETAILED DESCRIPTION

[0027] In one embodiment, a polypeptide synthesis reactor filtration device includes a connecting frame having a filter screen and a filter cotton. Figures 1-4 As shown in the figure, a polypeptide synthesis reactor filtration device includes a connecting frame having a filter screen and a filter cotton. The connecting frame has a feed inlet, a discharge pipe, a first electromagnetic valve, a fixing device, a reaction kettle, a motor, a stirring rod, a feed pipe, a connecting pipe, and a second electromagnetic valve. The filter screen and the filter cotton are fixedly connected to the inner wall of the connecting frame. The feed inlet is provided on the top of the connecting frame. The discharge pipe is provided on the bottom of the connecting frame. The first electromagnetic valve is provided on the surface of the discharge pipe. The fixing device is provided on the surface of the feed inlet. The reaction kettle is provided on the top of the feed inlet. The motor is fixedly connected to the top of the reaction kettle. The output end of the motor is fixedly connected to the stirring rod. The feed pipe is provided on the top of the reaction kettle. The connecting pipe is fixedly connected to the bottom of the reaction kettle. The second electromagnetic valve is provided on the surface of the connecting pipe. The connecting frame is provided with a connecting device. When the filtration device is used, the polypeptide synthesis material and solution are introduced into the connecting frame through the feed inlet. The filter screen and the filter cotton in the connecting frame can separate the solution and solid material, which facilitates the separation of the polypeptide-containing material.

[0028] Referring to Figure 2 and Figure 3The fixing device 7 comprises a sliding bar 701 fixedly connected with the surface of the feeding port 5, a sliding groove 702 is arranged on the inner wall of the bottom of the connecting pipe 14, the inner wall of the sliding groove 702 is slidably connected with the sliding bar 701, the inner wall of the sliding groove 702 is fixedly connected with a rubber strip 703, when the fixing device 7 is used, the feeding port 5 is manually slid into the inner wall of the bottom of the connecting pipe 14, and then the sliding bar 701 is slid into the sliding groove 702, after the sliding bar 701 is completely slid into the sliding groove 702, the rubber strip 703 is pressed to the bottom of the sliding bar 701, so that the sliding bar 701 is limited in the sliding groove 702 by the rubber strip 703, so that the filtering device can be arranged at the bottom of the reaction kettle 10 when needed, and the working diversity of the reaction kettle 10 is realized to a certain extent, a circular groove 704 is arranged on the surface of the connecting pipe 14, a semicircular ring 707 is arranged on the inner wall of the circular groove 704, an L-shaped plate 708 is fixedly connected to the bottom of the semicircular ring 707, the end of the L-shaped plate 708 away from the semicircular ring 707 is arranged at the bottom of the sliding bar 701, the semicircular ring 707 is slid into the circular groove 704, and then the end of the L-shaped plate 708 away from the semicircular ring 707 is arranged at the bottom of the sliding bar 701, so that the sliding bar 701 can be well limited in the sliding groove 702, the first damping rod 705 is uniformly fixedly connected to the inner wall of the circular groove 704, one end of the first damping rod 705 away from the circular groove 704 is fixedly connected with one side of the inner wall of the semicircular ring 707, the first spring 706 is arranged on the surface of the first damping rod 705, one end of the first spring 706 is fixedly connected with one side of the inner wall of the circular groove 704, the other end of the first spring 706 close to the first damping rod 705 is fixedly connected with one side of the semicircular ring 707, the semicircular ring 707 is pulled to the direction close to the circular groove 704 by the first spring 706, so that the semicircular ring 707 can be well arranged in the circular groove 704, and then one end of the L-shaped plate 708 is arranged at the bottom of the sliding bar 701, the clamping ring 709 is slidably arranged on the surface of the connecting pipe 14, the clamping ring 709 is slidably arranged on the surface of the L-shaped plate 708, the rubber blocks 710 are uniformly fixedly connected to the surface of the L-shaped plate 708, the two rubber blocks 710 are arranged on the two sides of the clamping ring 709, the clamping ring 709 is manually sleeved on the surface of the connecting pipe 14 and the L-shaped plate 708, and then the clamping ring 709 is limited in the middle of the two rubber blocks 710, so that the clamping ring 709 can be well limited on the surface of the L-shaped plate 708 by the rubber blocks 710.

[0029] Referring to Figure 4The connecting device 8 comprises a first connecting block 801 and a second connecting block 802, the inner wall of the first connecting block 801 is provided with a positioning groove 807, the inner wall of the second connecting block 802 is fixedly connected with a connecting ring 805, one side of the connecting ring 805 is fixedly connected with a rubber ring 806, the rubber ring 806 is arranged in the inside of the positioning groove 807, when the connecting device 8 is used, the connecting ring 805 is manually slid to the inner wall of the first connecting block 801, and then the rubber ring 806 is squeezed into the inside of the positioning groove 807, so that the first connecting block 801 and the second connecting block 802 can be well arranged together, reverse operation facilitates disassembly of the connecting frame 1, and then the filter screen 2 and the filter cotton 3 in the connecting frame 1 are facilitated to be cleaned, the bottom of the first connecting block 801 is provided with a fixing groove 803, the inner wall of the fixing groove 803 is slidably connected with a fixing ring 804, one end of the fixing ring 804 away from the fixing groove 803 is fixedly connected with the top of the second connecting block 802, the fixing ring 804 is slid into the inside of the fixing groove 803, so that the connection between the first connecting block 801 and the second connecting block 802 is more compact, the surface of the second connecting block 802 is uniformly fixedly connected with a connecting frame 808, the top of the connecting frame 808 is rotatably inserted with a round rod 809, the top of the round rod 809 is fixedly connected with a clamping plate 810, the clamping plate 810 is arranged on the top of the first connecting block 801, the clamping plate 810 is manually controlled to drive the round rod 809 to rotate, and then the clamping plate 810 is arranged on the top of the first connecting block 801, so that the first connecting block 801 and the second connecting block 802 can be well limited together, the top of the first connecting block 801 is uniformly fixedly connected with a clamping block 811, the two clamping blocks 811 are arranged on the two sides of the clamping plate 810, because the material of the clamping block 811 is rubber, the clamping plate 810 is limited in the middle of the two clamping blocks 811, and then the clamping plate 810 is well limited on the top of the first connecting block 801.

[0030] The working principle is that when the filtering device is used, the synthetic polypeptide material and solution enter the inside of the connecting frame 1 through the feeding port 5, and the filter screen 2 and the filter cotton 3 arranged in the inside of the connecting frame 1 can well separate the solution and the solid material, so that the polypeptide-containing material can be separated. When the fixing device 7 is used, the feeding port 5 is manually slid into the bottom inner wall of the connecting pipe 14, and then the sliding bar 701 is slid into the sliding groove 702. After the sliding bar 701 is completely slid into the sliding groove 702, the rubber strip 703 is squeezed to the bottom of the sliding bar 701, the semicircular ring 707 is slid into the circular groove 704, the semicircular ring 707 is pulled towards the circular groove 704 through the first spring 706, so that the semicircular ring 707 can be well arranged in the circular groove 704. Then the clamping ring 709 is manually sleeved on the surface of the connecting pipe 14 and the L-shaped plate 708, and then the clamping ring 709 is limited in the middle of the two rubber blocks 710, so that the clamping ring 709 can be well limited on the surface of the L-shaped plate 708 through the rubber block 710, and then the end of the L-shaped plate 708 away from the semicircular ring 707 is arranged at the bottom of the sliding bar 701, so that the sliding bar 701 can be well limited in the sliding groove 702. In this way, the filtering device can be arranged at the bottom of the reaction kettle 10 when the filtering device needs to be used, so that the diversity of the working of the reaction kettle 10 can be achieved to a certain extent. When the connecting device 8 is used, the connecting ring 805 is manually slid into the inner wall of the first connecting block 801, and then the rubber ring 806 is squeezed into the positioning groove 807, so that the first connecting block 801 and the second connecting block 802 can be well arranged together. The fixing ring 804 is slid into the fixing groove 803, so that the connection between the first connecting block 801 and the second connecting block 802 is more compact. The clamping plate 810 is manually controlled to drive the circular rod 809 to rotate, because the material of the clamping block 811 is rubber, the clamping plate 810 is limited in the middle of the two clamping blocks 811, so that the clamping plate 810 can be well limited on the top of the first connecting block 801, and then the clamping plate 810 is arranged on the top of the first connecting block 801, so that the first connecting block 801 and the second connecting block 802 can be well limited together. Reverse operation can facilitate disassembly of the connecting frame 1, so that the filter screen 2 and the filter cotton 3 in the inside of the connecting frame 1 can be conveniently cleaned.

[0031] It should be noted that all the damping rods in the case are telescopic dampers, which can absorb energy during telescoping.

Claims

1. A filtration device for a polypeptide synthesis reactor, comprising a connecting frame (1), characterized in that: A filter screen (2) is fixedly connected to the inner wall of the connecting frame (1), and a filter cotton (3) is fixedly connected to the inner wall of the connecting frame (1). A feed inlet (5) is provided at the top of the connecting frame (1), and a discharge pipe (4) is provided at the bottom of the connecting frame (1). A first solenoid valve (6) is provided on the surface of the discharge pipe (4). A fixing device (7) is provided on the surface of the feed inlet (5). A reaction vessel (10) is provided at the top of the feed inlet (5). A support frame (9) is fitted on the surface of the reaction vessel (10). A motor (11) is fixedly connected to the top of the reaction vessel (10), and a stirring rod is fixedly connected to the output end of the motor (11). (12) The top of the reactor (10) is provided with a feed pipe (13), the bottom of the reactor (10) is fixedly connected with a connecting pipe (14), the surface of the connecting pipe (14) is provided with a second solenoid valve (15), the surface of the connecting frame (1) is provided with a connecting device (8), the fixing device (7) includes a sliding strip (701), the sliding strip (701) and the surface of the feed port (5) are fixedly connected, the inner wall of the bottom of the connecting pipe (14) is provided with a groove (702), the inner wall of the groove (702) is slidably connected with the sliding strip (701), and the inner wall of the groove (702) is fixedly connected with a rubber strip (703).

2. The filtration device for a polypeptide synthesis reactor according to claim 1, characterized in that: The surface of the connecting pipe (14) is provided with a circular groove (704), and a semi-circular ring (707) is fitted on the inner wall of the circular groove (704). An L-shaped plate (708) is fixedly connected to the bottom of the semi-circular ring (707), and the end of the L-shaped plate (708) away from the semi-circular ring (707) is located at the bottom of the sliding bar (701).

3. The filtration device for a polypeptide synthesis reactor according to claim 2, characterized in that: The inner wall of the circular groove (704) is uniformly and fixedly connected with a first damping rod (705). The end of the first damping rod (705) away from the circular groove (704) is fixedly connected to one side of the inner wall of the semi-circular ring (707). A first spring (706) is sleeved on the surface of the first damping rod (705). One end of the first spring (706) is fixedly connected to one side of the inner wall of the circular groove (704). The end of the first spring (706) close to the first damping rod (705) is fixedly connected to one side of the semi-circular ring (707).

4. The filtration device for a polypeptide synthesis reactor according to claim 1, characterized in that: A locking ring (709) is slidably sleeved on the surface of the connecting pipe (14). The locking ring (709) is slidably sleeved on the surface of the L-shaped plate (708). Rubber blocks (710) are uniformly fixedly connected to the surface of the L-shaped plate (708). Two rubber blocks (710) are respectively set on both sides of the locking ring (709).

5. The filtration device for a polypeptide synthesis reactor according to claim 1, characterized in that: The connecting device (8) includes a first connecting block (801) and a second connecting block (802). The inner wall of the first connecting block (801) is provided with a positioning groove (807). The inner wall of the second connecting block (802) is fixedly connected with a connecting ring (805). A rubber ring (806) is fixedly connected to one side of the connecting ring (805). The rubber ring (806) is disposed inside the positioning groove (807).

6. The filtration device for a polypeptide synthesis reactor according to claim 5, characterized in that: The bottom of the first connecting block (801) is provided with a fixing groove (803), and a fixing ring (804) is slidably connected to the inner wall of the fixing groove (803). The end of the fixing ring (804) away from the fixing groove (803) is fixedly connected to the top of the second connecting block (802).

7. The filtration device for a polypeptide synthesis reactor according to claim 5, characterized in that: The surface of the second connecting block (802) is uniformly fixedly connected with a connecting frame (808), and a round rod (809) is rotatably inserted into the top of the connecting frame (808). A positioning plate (810) is fixedly connected to the top of the round rod (809), and the positioning plate (810) is located on the top of the first connecting block (801).

8. A filtration device for a polypeptide synthesis reactor according to claim 5, characterized in that: The top of the first connecting block (801) is uniformly fixedly connected with a locking block (811), and the two locking blocks (811) are respectively arranged on both sides of the locking plate (810).

Citation Information

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