Antenatal villus sample bottle

Abstract

The utility model relates to the technical field of villus sample collection bottles, and provides an antenatal villus sample bottle which comprises a sample bottle body, a medicine storage device, a puncture outfit and a safety ring, the medicine storage device is detachably arranged on the sample bottle body, a medicine storage cavity is formed in the medicine storage device, and the medicine storage device is provided with a medicine outlet communicating with the medicine storage cavity and a bottle opening. The isolating membrane covers the medicine outlet, one end of the puncture outfit penetrates through the medicine storage device and is located in the medicine storage cavity to form a puncture part, the puncture part is slidably arranged on the medicine storage device in the puncture direction, and the safety ring is detachably connected with the puncture outfit and the medicine storage device. By arranging the medicine storage device for containing heparin sodium medicine and the sample bottle body for containing normal saline, when an antenatal villus sample needs to be collected, the isolating membrane is punctured through the puncture outfit, so that heparin sodium in a certain proportion in the medicine storage device is scattered into the sample bottle body to be mixed with the normal saline; the preparation method has the advantages of high speed and high efficiency, and can be used for completely eradicating the loss caused by wrong proportioning.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of villus sample collection bottles, in particular to a prenatal villus sample bottle. BACKGROUND

[0002] Prenatal chorionic villus sampling (CVS) is a procedure in prenatal diagnosis that involves obtaining a sample of chorionic villi, which are part of the placenta, using a needle and syringe from the body of a pregnant woman. Chorionic villi are rich in fetal cells and can accurately reflect the genetic information of the fetus. Collecting prenatal chorionic villus samples in prenatal diagnosis laboratories for cytogenetic and molecular genetic testing and data analysis is a prenatal diagnostic technique for early pregnancy. This technique is usually performed before the 11th to 14th week of pregnancy by extracting a suitable amount of chorionic villus sample from the chorionic membrane of the placenta (i.e. the early form of the placenta) for analysis. The main purpose is to detect whether the prenatal fetus has chromosomal and genetic diseases such as chromosomal diseases such as Down syndrome, Edward syndrome, etc.; or spinal muscular atrophy, Huntington's disease, and various single-gene genetic diseases that are relatively rare.

[0003] During the clinical collection of prenatal chorionic villus samples, the sample surface is prone to mixing with maternal blood and forming blood clots, and maternal blood can contaminate the prenatal chorionic villus sample, resulting in false positives or false negatives in laboratory testing data later. To ensure the authenticity of prenatal chorionic villus data analysis, an anticoagulant solution needs to be added to the sample bottle to prevent maternal blood from adhering to the prenatal chorionic villus sample. The anticoagulant solution needs to be prepared on site, and long-term storage will reduce the anticoagulant effect and affect laboratory testing. The existing prenatal chorionic villus sample bottle is basically an empty bottle, so medical personnel need to add physiological saline and a certain proportion of heparin sodium medicament to the sample bottle to configure a mixed solution as an anticoagulant solution before placing the prenatal chorionic villus sample for storage. The configuration process not only consumes time and effort, but also can result in errors in the proportion of physiological saline and heparin sodium medicament configured by hand, causing unnecessary losses. CONTENT OF THE UTILITY MODEL

[0004] In view of the above deficiencies of the prior art, the purpose of the present application is to provide a prenatal chorionic villus sample bottle to solve the problem of long time consumption in configuring an anticoagulant solution for the existing villus sample collection bottle.

[0005] The technical solution adopted by the present application to solve the technical problem is as follows: a prenatal chorionic villus sample bottle, comprising: a sample bottle body, the sample bottle body having a bottle mouth, the sample bottle body being used to contain physiological saline;

[0006] A medicine storage device is detachably arranged on the sample bottle body and covers the bottle opening arrangement, and the medicine storage device has a medicine storage cavity for accommodating heparin sodium medicine.

[0007] A separation film is arranged on the medicine outlet.

[0008] A puncture device has one end penetrating the medicine storage device to form a puncture part in the medicine storage cavity and is arranged on the medicine storage device in a puncture direction.

[0009] A safety ring is detachably connected with the puncture device and the medicine storage device and is used for limiting the puncture part from sliding in the puncture direction.

[0010] The puncture direction is the direction of the puncture part towards the separation film.

[0011] Further, the medicine storage device further comprises an embedding part arranged in the sample bottle body, and the medicine outlet is arranged on the embedding part.

[0012] A protruding part is arranged on the embedding part and arranged outside the sample bottle body.

[0013] A sliding opening is arranged on the protruding part and communicates with the medicine storage cavity, and the puncture part penetrates the sliding opening and is located in the medicine storage cavity.

[0014] The medicine storage cavity is arranged in the embedding part and the protruding part.

[0015] Further, the medicine storage device further comprises a first sealing part arranged on the embedding part and used for sealing the gap between the embedding part and the sample bottle body.

[0016] Further, the puncture device further comprises a pressing part driven to slide in the puncture direction.

[0017] A connecting part is connected with the pressing part and the puncture part and is arranged in the sliding opening in the puncture direction.

[0018] Further, the puncture device further comprises a second sealing part arranged on the connecting part, arranged in the medicine storage cavity in the puncture direction, and used for sealing the gap between the connecting part and the sliding opening.

[0019] Further, the pressing part is provided with a sliding groove on the surface facing the convex part, and the convex part is slidably arranged on the sliding groove along the puncture direction.

[0020] Further, the puncture part has an outer diameter greater than that of the connecting part.

[0021] The puncture part is in interference connection with the medicine outlet, and the isolation film is arranged in the medicine storage cavity.

[0022] Further, the medicine storage device further comprises a limiting ring, the limiting ring is fixedly sleeved on the medicine storage device, the limiting ring has an outer diameter greater than an inner diameter of the bottle opening, and the limiting ring is used for limiting the convex part from entering the sample bottle body.

[0023] Further, the safety ring is sleeved on the convex part, and the safety ring is detachably connected with the limiting ring and the pressing part respectively.

[0024] Further, the puncture device further comprises a first threaded part, the first threaded part is arranged on the connecting part, and the connecting part is in threaded connection with the medicine storage device through the first threaded part.

[0025] The medicine storage device further comprises a second threaded part, the second threaded part is arranged on the embedded part, and the embedded part is in threaded connection with the sample bottle body through the second threaded part.

[0026] Compared with the prior art, the medicine storage device containing heparin sodium and the sample bottle body containing physiological saline are arranged, the isolation film is punctured by the puncture device when the prenatal villus sample needs to be collected, a certain proportion of heparin sodium in the medicine storage device is scattered into the sample bottle body to be mixed with the physiological saline, and the preparation of the anticoagulant solution is completed after being inverted and shaken, so that the speed is fast, the efficiency is high, and the loss caused by the proportioning error can be avoided. BRIEF DESCRIPTION OF DRAWINGS

[0027] In order to more clearly illustrate the technical scheme in the embodiments of the present application or the prior art, the drawings needed to be used in the following embodiment or prior art description will be briefly introduced. Obviously, the drawings in the following description are some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.

[0028] Figure 1 is a whole structure schematic view of the prenatal villus sample bottle provided by the present embodiment;

[0029] Figure 2 is a sectional view of the prenatal villus sample bottle (after disassembly) provided by the present embodiment;

[0030] Figure 3 is a schematic diagram of the overall structure of a prenatal chorionic sample bottle provided by another embodiment;

[0031] Figure 4 is a schematic diagram of the overall structure of a prenatal chorionic sample bottle provided by another embodiment.

[0032] In the figure: 100, sample bottle body; 110, bottle mouth; 200, medicine storage device; 210, embedded part; 211, medicine outlet; 220, protruding part; 221, sliding opening; 222, medicine storage cavity; 230, limiting ring; 240, first sealing part; 250, isolation film; 260, first threaded part; 300, puncture device; 310, pressing part; 311, sliding groove; 320, connecting part; 330, puncture part; 340, second sealing part; 350, second threaded part; 400, safety ring; 500, puncture direction. DETAILED DESCRIPTION

[0033] The embodiments of the present application are described in detail below with reference to the accompanying drawings. The embodiments described below are exemplary only, and are used only for explaining the present application, and cannot be understood as limiting the present application.

[0034] In the description of the present application, it should be understood that the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer" and the like indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second" are only for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined as "first", "second" can explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise specified, the meaning of "a plurality of" is two or more.

[0035] In the description of the present application, it should be noted that unless otherwise specified and limited, the terms "mounting", "connecting", "connecting" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication between the two elements inside. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0036] In addition, the technical features involved in the different embodiments of the utility model described above can be combined with each other as long as they do not conflict with each other.

[0037] The utility model provides a kind of prenatal villus sample bottle as shown in Figures 1 to 4 The prenatal villus sample bottle is aimed to solve the problem of long time consumption of existing villus sample collection bottle configuration anticoagulant solution.

[0038] The prenatal villus sample bottle mainly includes: a sample bottle body 100, a medicine storage device 200, an isolation membrane 250, a puncture device 300 and a safety ring 400.

[0039] Specifically, the sample bottle body 100 is used to contain physiological saline, the medicine storage device 200 is used to contain heparin sodium medicine, the puncture device 300 is used to puncture the isolation membrane 250 to scatter the heparin sodium medicine in the medicine storage cavity 222 into the sample bottle body 100 to mix with physiological saline, and the safety ring 400 is used to limit the movement of the puncture device 300 to avoid the isolation membrane 250 being punctured due to factors such as vibration during storage.

[0040] The sample bottle body 100 has a bottle mouth 110, the medicine storage device 200 is detachably arranged on the sample bottle body 100, preferably threaded connection, convenient storage and use. And the medicine storage device 200 covers the bottle mouth 110, and in the storage process, the medicine storage device 200 can close the bottle mouth 110 of the sample bottle body 100 to avoid the physiological saline in the sample bottle body 100 flowing out or being contaminated. The medicine storage device 200 has a medicine storage cavity 222, which is used to contain heparin sodium medicine. The medicine storage device 200 has a medicine outlet 211 communicating with the medicine storage cavity 222 and the bottle mouth 110 respectively, and the isolation membrane 250 is arranged on the medicine outlet 211. One end of the puncture device 300 penetrates the medicine storage device 200 to form a puncture part 330 in the medicine storage cavity 222, and the puncture part 330 is slidably arranged on the medicine storage device 200 along the puncture direction 500. The safety ring 400 is detachably connected with the puncture device 300 and the medicine storage device 200 respectively, and the safety ring 400 is used to limit the sliding of the puncture part 330 along the puncture direction 500, wherein the puncture direction 500 is the direction of the puncture part 330 towards the isolation membrane 250.

[0041] In actual use, the sample bottle body 100 is preloaded with an appropriate amount of physiological saline, the storage cavity 222 is preloaded with an appropriate amount of heparin sodium medicine, the amount of heparin sodium medicine and the amount of physiological saline are a prescribed ratio, and the storage cavity 222 and the sample bottle body 100 are separated by the isolation film 250. Before the extracted prenatal villi are prepared to be bottled, the medical staff presses the puncture device 300, the puncture part 330 on the puncture device 300 moves towards the direction of the isolation film 250 until the isolation film 250 is pierced, at which time the storage cavity 222 and the sample bottle body 100 are communicated through the medicine outlet 211, and the heparin sodium medicine in the storage cavity 222 is scattered into the sample bottle body 100 to mix with the physiological saline. The heparin sodium medicine can be completely dissolved in the physiological saline by inverting and shaking the sample bottle body 100, at which time the medicine storage device 200 is removed from the sample bottle body 100, and the prenatal villi can be loaded into the sample bottle body 100. At present, the anticoagulant solution needs to be manually configured, the proportion is 100 mL of physiological saline and 2 mg of heparin sodium medicine, the configuration link is relatively time-consuming, and the physiological saline and the heparin sodium medicine are often misconfigured. Through the present application, the time and efficiency of configuring the anticoagulant solution can be improved.

[0042] The utility model mainly aims at the pregnant women who need to do invasive operation to obtain prenatal villus sample in prenatal diagnosis center, and there is a certain difficulty in collecting prenatal villus sample, and the collected villus sample is trace, so the sample is very precious. For prenatal villus sample, strict quality control is required in sampling and after sampling in clinic. Under normal circumstances, secondary repeated sampling will not be carried out, because secondary repeated sampling will increase the risk of intrauterine fetal abortion and infection of pregnant women. Therefore, preventing maternal blood pollution of prenatal villus sample is also one of the important links.

[0043] Due to the particularity of the sample, it is convenient to have a more secure and more convenient storage container after collecting the prenatal villus sample, so a special container bottle for storing prenatal villus sample after extracting prenatal villus for prenatal diagnosis is needed. The function is to store the collected villus sample in a mixed solution of physiological saline and heparin sodium medicine with a fixed proportion. Through the inhibition of heparin on thrombin activity, the aggregation of platelets is prevented, so as to prevent the maternal blood from adhering to the prenatal villus. The purpose is to avoid the prenatal villus sample from being contaminated by maternal blood and affect the authenticity of the subsequent detection data analysis of the prenatal villus sample in the laboratory.

[0044] After the prenatal villus sample is extracted clinically, it is difficult to avoid the sample from contacting the maternal blood, and generally, maternal blood will adhere to the surface of the prenatal villus sample after the prenatal villus sample is collected, and the maternal blood coagulation on the prenatal villus will cause the risk of false positive or false negative in the laboratory detection and analysis of the prenatal villus data in the later period, so it is necessary to pour an anticoagulation solution into the sample storage bottle. The anticoagulation solution needs to be prepared and used immediately, and the anticoagulation activity will be reduced after a long time of storage, and the existing sample storage bottle is basically an empty bottle, so the medical staff needs to add physiological saline and a certain proportion of heparin sodium medicament in the sample storage bottle to mix and configure the anticoagulation solution for use, and the configuration process not only wastes time, manpower and material resources, but also causes the proportion error of the manually configured heparin sodium, thereby causing unnecessary loss.

[0045] The utility model discloses a drug storage device for prenatal villus sample, which comprises a sample bottle body 100 and a drug storage device 200, wherein the drug storage device 200 is arranged in the sample bottle body 100.

[0046] In some embodiments, as shown in Figures 1 to 4 The drug storage device 200 further comprises an embedding part 210 and a protruding part 220.

[0047] The protruding part 220 is arranged outside the sample bottle body 100.

[0048] The drug storage device 200 further comprises a sliding port 221 and a drug storage cavity 222.

[0049] The drug storage cavity 222 is arranged in the embedding part 210 and the protruding part 220.

[0050] Specifically, after the anticoagulation solution is configured, the protruding part 220 can be pinched to take the whole drug storage device 200 out of the sample bottle body 100, so as to expose the bottle opening 110, and the prenatal villus can be conveniently loaded into the sample bottle body 100.

[0051] In some embodiments, as shown in Figures 1 to 4 The drug storage device 200 further comprises a first sealing part 240.

[0052] Specifically, the first sealing part 240 is a rubber sealing ring, so that the medicine storage device 200 can better seal the bottle opening 110 of the sample bottle body 100, and avoid the physiological saline in the sample bottle body 100 from being contaminated.

[0053] In some embodiments, as shown in Figures 1 to 4 , the puncture device 300 further comprises a pressing part 310, the pressing part 310 is driven to slide in the puncture direction 500;

[0054] A connecting part 320, the connecting part 320 respectively connects the pressing part 310 and the puncture part 330, and the connecting part 320 is slidably arranged in the sliding opening 221 along the puncture direction 500.

[0055] Preferably, the connecting part 320 is coaxially arranged with the sample bottle body 100, and the puncture direction 500 is the axial direction of the sample bottle body 100.

[0056] In some embodiments, as shown in Figures 1 to 4 , the puncture device 300 further comprises a second sealing part 340, the second sealing part 340 is arranged on the connecting part 320, the second sealing part 340 is slidably arranged in the medicine storage cavity 222 along the puncture direction 500, and the second sealing part 340 is used to seal the gap between the connecting part 320 and the sliding opening 221.

[0057] Specifically, the second sealing part 340 is a rubber plug, and after the second sealing part 340 is connected with the connecting part 320, the second sealing part 340 is slidably arranged in the medicine storage cavity 222, so that the second sealing part 340, the connecting part 320 and the medicine storage cavity 222 form a structure of a syringe. When a medical staff presses the puncture device 300, the heparin sodium medicine in the medicine storage cavity 222 will be injected into the sample bottle body 100 as if using a syringe to inject, and the residual heparin sodium medicine in the medicine storage cavity 222 is reduced.

[0058] In some embodiments, as shown in Figures 1 to 4 , the pressing part 310 is provided with a sliding groove 311 on the surface facing the protruding part 220, and the protruding part 220 is slidably arranged on the sliding groove 311 along the puncture direction 500.

[0059] Specifically, the sliding groove 311 is an annular sliding groove 311, the protruding part 220, the pressing part 310 and the sliding groove 311 are coaxially arranged, and the pressing part 310 and the protruding part 220 can move relative to each other along the axial direction. When the pressing part 310 is pressed, the pressing part 310 can slide on the protruding part 220, which can improve the stability of the movement of the puncture part 330, so that the puncture part 330 can better pierce the isolation film 250.

[0060] In some embodiments, as shown in Figures 1 to 4 , the outer diameter of the puncture part 330 is greater than the outer diameter of the connecting part 320;

[0061] The puncture part 330 is in interference connection with the medicine outlet 211. When the puncture part 330 pierces the isolation film 250, the puncture part 330 is in sealed connection with the medicine outlet 211, so that the sample in the sample bottle body 100 does not contact the isolation film 250.

[0062] The isolation film is arranged in the medicine storage cavity. The distance between the isolation film and the medicine outlet 211 is adjusted as required, preferably more than 1 cm. When the puncture part 330 pierces the isolation film 250, the puncture part 330 continues to move towards the medicine outlet 211 until the puncture part 330 is in sealed connection with the medicine outlet 211. At this time, the isolation film 250 stays in the medicine storage cavity 222 and does not contact the sample in the sample bottle body 100.

[0063] Specifically, the connecting part 320 is slidingly arranged in the sliding opening 221. The outer diameter of the puncture part 330 is greater than the outer diameter of the connecting part 320, so that the puncture part 330 cannot pass through the sliding opening 221 to leave the medicine storage cavity 222. The area of the puncture part 330 can be increased, so that the puncture part 330 can form a larger tear after piercing the isolation film 250, and the heparin sodium medicine in the medicine storage cavity 222 can be better scattered into the sample bottle body 100, reducing the residual heparin sodium medicine in the medicine storage cavity 222.

[0064] In some embodiments, as shown in Figures 1 to 4 , the medicine storage device 200 further comprises a limiting ring 230, the limiting ring 230 is fixedly sleeved on the medicine storage device 200, the outer diameter of the limiting ring 230 is greater than the inner diameter of the bottle opening 110, and the limiting ring 230 is used to limit the convex part 220 from entering the sample bottle body 100.

[0065] In some embodiments, as shown in Figures 1 to 4 , the safety ring 400 is sleeved on the convex part 220, and the safety ring 400 is detachably connected with the limiting ring 230 and the pressing part 310, respectively.

[0066] Specifically, the safety ring 400 is arc-shaped, one end of which is outwardly bent to form a hand tearing part. When in use, the entire safety ring 400 can be separated from the limiting ring 230 and the pressing part 310 by pinching and pulling the hand tearing part. The specific structure of the safety ring 400 is shown in Figures 1 to 3 .

[0067] In some embodiments, as shown in Figures 1 to 4 , the sample bottle body 100 has multiple capacity specifications, preferably a conical bottom (for a small amount of prenatal villus sample, as shown in Figures 1 to 2 , Figure 4 , and a flat bottom (for a large amount of prenatal villus sample, as shown in Figure 3 ).

[0068] The isolation film 250 is an aluminum foil film. It is convenient to pierce and waterproof, and physiological saline can be prevented from penetrating.

[0069] The puncture device further comprises a first threaded portion arranged on the connecting portion, and the connecting portion is threadedly connected with the medicine reservoir through the first threaded portion;

[0070] In some embodiments, as shown in Figure 4 The puncture device 300 further comprises a first threaded portion 260 arranged on the connecting portion 320, and the connecting portion 320 is threadedly connected with the medicine reservoir 200 through the first threaded portion 260.

[0071] Specifically, the connecting portion 320 is threadedly connected with the medicine reservoir 200 through the first threaded portion 260, and the pressing portion 310 can be moved towards or away from the isolation film 250 by rotating, so as to facilitate the medical staff to pierce the isolation film 250. Preferably, the pressing portion 310 is provided with anti-skid lines for increasing the friction with the hand, so as to facilitate the rotation of the pressing portion 310. Preferably, the puncture portion 330 is made of rubber and is sealingly connected with the medicine storage cavity 222. When the isolation film 250 is pierced, the puncture portion 330 and the sample bottle body 100 form a space for storing the sample, so as to prevent the sample from leaking out.

[0072] The medicine reservoir 200 further comprises a second threaded portion 350 arranged on the embedded portion 210, and the embedded portion 210 is threadedly connected with the sample bottle body 100 through the second threaded portion 350.

[0073] Specifically, the embedded portion 210 is threadedly connected with the sample bottle body 100 through the second threaded portion 350, so as to improve the stability of the connection between the embedded portion 210 and the sample bottle body 100 and prevent the embedded portion 210 from being separated from the sample bottle body 100 due to accidental falling.

[0074] In summary, the prenatal villus sample bottle comprises a sample bottle body, a medicine reservoir, a puncture device and a safety ring. The medicine reservoir is detachably arranged on the sample bottle body and has a medicine storage cavity. The medicine reservoir has a medicine outlet communicating with the medicine storage cavity and the bottle mouth. An isolation film is arranged on the medicine outlet. One end of the puncture device penetrates through the medicine reservoir to form a puncture portion in the medicine storage cavity. The puncture portion is slidingly arranged on the medicine reservoir along a puncture direction. The safety ring is detachably connected with the puncture device and the medicine reservoir. The prenatal villus sample bottle has the advantages that the medicine reservoir containing heparin sodium and the sample bottle body containing physiological saline are arranged. When the prenatal villus sample needs to be collected, the isolation film is pierced by the puncture device, so that a certain proportion of heparin sodium in the medicine reservoir is scattered into the sample bottle body to mix with the physiological saline. After being inverted and shaken, the anticoagulant solution is prepared. The method is fast, efficient and can prevent the loss caused by the ratio error.

[0075] Obviously, the above embodiments are only examples for clearly illustrating the present application and are not intended to limit the present application. Based on the above description, other different forms of changes or variations can be made by those skilled in the art. Here, all the embodiments are not required to be enumerated. The changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A prenatal chorionic villus sample vial, characterized by, The application relates to a sample bottle, which comprises: a sample bottle body having a bottle mouth, the sample bottle body being used for containing physiological saline; a medicine storage device which is detachably arranged on the sample bottle body and covers the bottle mouth, the medicine storage device having a medicine storage cavity used for containing heparin medicine in the interior; an isolation film which is arranged on the medicine outlet of the medicine storage cavity and the bottle mouth respectively; a puncture device which is arranged in the medicine storage cavity through the medicine storage device and is slidably arranged on the medicine storage device in a puncture direction; a safety ring which is detachably connected with the puncture device and the medicine storage device and is used for limiting the sliding of the puncture device in the puncture direction; wherein the puncture direction is the direction of the puncture device towards the isolation film.

2. The prenatal chorionic sample vial according to claim 1, characterized in that, The medicine storage device further comprises an embedded part which is arranged in the sample bottle body and on which the medicine outlet is arranged; a protruding part which is arranged on the embedded part and is arranged outside the sample bottle body; a sliding opening which is arranged on the protruding part and is communicated with the medicine storage cavity, and the puncture device passes through the sliding opening and is arranged in the medicine storage cavity; wherein the medicine storage cavity is arranged in the embedded part and the protruding part.

3. The prenatal chorionic sample vial of claim 2, wherein, The medicine storage device further comprises a first sealing part which is arranged on the embedded part and is used for sealing the gap between the embedded part and the sample bottle body.

4. The prenatal chorionic sample vial of claim 2, wherein, The puncture device further comprises a pressing part which is driven to slide in the puncture direction; a connecting part which is connected with the pressing part and the puncture part respectively and is slidably arranged in the sliding opening in the puncture direction.

5. The prenatal chorionic sample vial of claim 4, wherein, The puncture device further comprises a second sealing part which is arranged on the connecting part, is slidably arranged in the medicine storage cavity in the puncture direction and is used for sealing the gap between the connecting part and the sliding opening.

6. The prenatal chorionic sample vial of claim 4, wherein, A sliding groove is arranged on the surface of the pressing part which faces the protruding part, and the protruding part is slidably arranged on the sliding groove in the puncture direction.

7. The prenatal chorionic sample vial of claim 4, wherein, The outer diameter of the puncture part is greater than that of the connecting part; the puncture part is in interference connection with the medicine outlet, and the isolation film is arranged in the medicine storage cavity.

8. The prenatal chorionic sample vial of claim 4, wherein, The medicine storage device further comprises a limiting ring which is fixedly sleeved on the medicine storage device, the outer diameter of the limiting ring is greater than the inner diameter of the bottle mouth, and the limiting ring is used for limiting the entry of the protruding part into the sample bottle body.

9. The prenatal chorionic sample vial of claim 8, wherein, The safety ring is sleeved on the protruding part and is detachably connected with the limiting ring and the pressing part respectively.

10. The prenatal chorionic sample vial of claim 4, wherein, The puncture device further comprises a first threaded part which is arranged on the connecting part, and the connecting part is in threaded connection with the medicine storage device through the first threaded part; the medicine storage device further comprises a second threaded part which is arranged on the embedded part, and the embedded part is in threaded connection with the sample bottle body through the second threaded part.

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