Fibroin degumming equipment

Abstract

The utility model relates to silk protein degumming equipment which comprises a tank body, a stirring space is defined by the tank body, and the tank body is respectively provided with a feed port, a water injection port and a water outlet which are communicated with the stirring space; the stirring mechanism comprises a first driving part, a stirring shaft and a stirring paddle, the stirring paddle is located in the stirring space and connected to the stirring shaft, and the stirring shaft is connected to the output end of the first driving part; the feeding mechanism comprises a feeding pipe, a cutter, a baffle and a second driving part, and the feeding pipe is arranged at the feeding opening and communicates with the stirring space. Through the arrangement, the silk protein is cut up by the cutter, so that the clustered silk protein is broken, and the silk protein raw material and the degumming liquid in the stirring space are stirred by the stirring paddle, so that the silk protein raw material and the degumming liquid are fully mixed, and the degumming efficiency is further improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to degumming equipment field especially is a kind of silk fibroin degumming equipment. BACKGROUND

[0002] Silk is divided into sericin and silk fibroin, and silk fibroin is the main component, about 70-80%, because it has excellent biocompatibility, no immunogenicity, can be degraded in vivo and time controllable, and degradation product is safe and non-toxic, becoming a new type of medical biomaterial, which can be used as product directly in clinical tissue repair, and also can be used as drug and cell carrier support for drug release and tissue engineering construction artificial organ. Silk fibroin solution is light yellow clear protein aqueous solution obtained after a series of purification processes of degummed silk fiber, and silk fibroin solution is the basis for preparing silk fibroin forming material.

[0003] In the prior art, degumming of silk fibroin is mostly extracted by manual use of simple boiling tools, which needs multiple transfer sequences, and the extraction process is complicated, and the reaction of silk fibroin in lump with degumming liquid and degumming reagent is insufficient, resulting in low degumming efficiency. UTILITY MODEL CONTENT

[0004] Therefore, the utility model solves the problem that the reaction of silk fibroin with degumming liquid and degumming reagent is insufficient in the prior art, resulting in low degumming efficiency, so as to provide a silk fibroin degumming equipment.

[0005] To solve the above technical problems, the utility model provides a silk fibroin degumming equipment, which comprises:

[0006] A tank body is enclosed to form a stirring space, and the tank body is respectively provided with a feeding port, a water injection port and a water outlet port communicated with the stirring space;

[0007] A stirring mechanism comprises a first driving member, a stirring shaft and a stirring paddle, the stirring paddle is located in the stirring space and connected to the stirring shaft, and the stirring shaft is connected to the output end of the first driving member;

[0008] A feeding mechanism comprises a feeding pipe, a cutter, a baffle and a second driving member, the feeding pipe is arranged in the feeding port and communicated with the stirring space, the cutter is arranged on the first side of the feeding pipe, the baffle is arranged on the second side of the feeding pipe, and the cutter and the baffle are both connected to the output end of the second driving member.

[0009] In an embodiment of the utility model, the second driving member is a linear driving member, and the feeding pipe is respectively provided with a first avoiding hole and a second avoiding hole matched with the cutter and the baffle.

[0010] In an embodiment of the utility model, the cutter and the baffle are driven by the second driving member along the height direction and / or the horizontal direction.

[0011] In an embodiment of the utility model, the feeding pipe is obliquely arranged, and the end of the feeding pipe is gradually inclined downward toward the direction close to the center of the tank.

[0012] In an embodiment of the utility model, the projection area of the cutter and the baffle along the height direction does not coincide, and the distance between the baffle and the center of the tank is less than the distance between the cutter and the center of the tank.

[0013] In an embodiment of the utility model, the inner wall of the feeding pipe is provided with a cutting groove, and the cutter is adapted to the cutting groove.

[0014] In an embodiment of the utility model, the tank is provided with a discharging disc, and the discharging disc is sealingly connected to the inner wall of the tank.

[0015] In an embodiment of the utility model, one side of the discharging disc is provided with a heating unit, the tank is further provided with a control unit, and the first driving member, the second driving member and the heating unit are electrically connected to the control unit.

[0016] In an embodiment of the utility model, the tank is further provided with a sampling port communicating with the stirring space.

[0017] In an embodiment of the utility model, the height of the water inlet port relative to the bottom of the tank is greater than the height of the water outlet port relative to the bottom of the tank, and the height of the feeding port relative to the bottom of the tank is greater than the height of the sampling port relative to the bottom of the tank.

[0018] The above technical scheme of the utility model has the following advantages compared with the prior art:

[0019] The silkworm protein degumming equipment adds the silkworm protein to be degummed through the feeding port, drives the cutter and the baffle by the second driving member, cuts the silkworm protein by the cutter, removes the stop of the raw material in the feeding pipe by the movement of the baffle, makes the cut silkworm protein fall into the stirring space of the tank along the feeding pipe, breaks the silkworm protein lump, and transports the silkworm protein to be degummed to the stirring space through the feeding port and the feeding pipe, adds the degumming liquid, drives the stirring shaft to rotate by the first driving, and drives the stirring paddle to rotate in the stirring space by the stirring shaft. The stirring paddle stirs the silkworm protein raw material and the degumming liquid in the stirring space, fully mixes them, and further improves the degumming efficiency. BRIEF DESCRIPTION OF DRAWINGS

[0020] In order to make the content of the utility model more easily be clearly understood, the following according to the specific embodiment of the utility model and combining with the drawings, the utility model is further explained in detail, wherein

[0021] Figure 1 It is the structural schematic diagram of the degumming equipment of the utility model;

[0022] Figure 2 It is the utility model Figure 1 The enlarged view of A in the utility model;

[0023] Figure 3 It is the enlarged view of B in the utility model; Figure 2

[0024] Figure 4 It is the structural schematic diagram of the stirring shaft and stirring paddle of the utility model.

[0025] The description of the drawing of the specification is as follows: 1, discharging disc;2, tank body;3, water inlet;4, water outlet;5, support;61, second driving part;62, feed pipe;63, feed bin;64, lifting frame;65, guide sleeve;66, cutter;67, cushion block;68, cutting groove;69, baffle;7, speed reducer;8, first driving part;9, stirring shaft;10, stirring paddle;11, feed inlet;12, sampling port;13, heating unit. Specific embodiment

[0026] The utility model is further explained in conjunction with the drawings and specific embodiment, so that the person skilled in the art can better understand the utility model and can be implemented, but the embodiment is not as the limitation of the utility model.

[0027] Embodiment

[0028] Referring to Figures 1-4 The utility model discloses a silk protein degumming equipment,

[0029] Including:

[0030] Tank body 2 is enclosed and forms stirring space, and the tank body 2 is respectively provided with feed inlet 11, water inlet 3 and water outlet 4 communicated with stirring space;

[0031] Stirring mechanism, it includes: first driving part 8, stirring shaft 9 and stirring paddle 10, the stirring paddle 10 is located in stirring space and is connected to stirring shaft 9, and the stirring shaft 9 is connected to the output end of first driving part 8;

[0032] ​The feeding mechanism comprises a feeding pipe 62, a cutter 66, a baffle 69 and a second driving member 61, the feeding pipe 62 is arranged at the feeding port 11 and communicates with the stirring space, the cutter 66 is arranged at the first side of the feeding pipe 62, the baffle 69 is arranged at the second side of the feeding pipe 62, and the cutter 66 and the baffle 69 are connected to the output end of the second driving member 61.

[0033] The silkworm protein degumming equipment adds the silkworm protein to be degummed through the feeding port 11, drives the cutter 66 and the baffle 69 to move through the second driving member 61, cuts the silkworm protein through the cutter 66, removes the stop of the raw materials in the feeding pipe 62 through the movement of the baffle 69, makes the cut silkworm protein fall into the stirring space of the tank body 2 along the feeding pipe 62, and the silkworm protein raw material to be degummed is conveyed into the stirring space through the feeding port 11 and the feeding pipe 62, the degumming liquid is added through the water injection port 3, the degumming agent is added, the stirring shaft 9 is driven to rotate through the first driving, and the stirring paddle 10 is driven to rotate in the stirring space through the stirring shaft 9. The stirring paddle 10 stirs the silkworm protein raw material and the degumming liquid in the stirring space, so that they are fully mixed, and the degumming efficiency is improved.

[0034] The second driving member 61 is a linear driving member, and the feeding pipe 62 is respectively provided with a first avoiding hole and a second avoiding hole matched with the cutter 66 and the baffle 69. The linear driving member can be a cylinder, a hydraulic cylinder or a linear motor. In the embodiment, the cylinder is selected, and the cylinder has the advantages of simple structure, rapid action and low cost. The cross section of the feeding pipe 62 is circular or rectangular, and in the embodiment, the rectangular is selected. The first avoiding hole is arranged on the side of the feeding pipe 62 close to the cutter 66. The first avoiding hole is a rectangular through hole. The cutter 66 can be completely embedded in the first avoiding hole and cut off the channel in the feeding pipe 62 under the driving of the cylinder, so that the cutting operation of the silkworm protein is realized. The second avoiding hole is arranged on the side of the feeding pipe 62 close to the baffle 69. Since the output end of the cylinder is rigidly connected with the cutter 66 and the baffle 69 through the connecting member, the cutter 66 and the baffle 69 move synchronously along the linear direction.

[0035] The cutter 66 and the baffle 69 are driven by the second driving member 61 in the height direction and / or the horizontal direction. When the feeding pipe 62 is arranged at the side of the tank body 2, the cutter 66 and the baffle 69 are driven by the second driving member 61 in the height direction. When the feeding pipe 62 is arranged at the top of the tank body 2, the cutter 66 and the baffle 69 are driven by the second driving member 61 in the horizontal direction. In the embodiment, the feeding pipe 62 is arranged at the side of the tank body 2. During the downward movement of the cutter 66, the silk fibroin in the feeding pipe 62 is cut. At the same time, the baffle 69 also moves downward in the height direction, gradually removing the blockage of the channel of the feeding pipe 62. The cut silk fibroin falls into the stirring space of the tank body 2 under the action of gravity. After the feeding is completed, the second driving member 61 is driven in the direction, and the cutter 66 and the baffle 69 move upward in the height direction of the feeding pipe 62 to return to the initial position. The cutter 66 returns to above the feeding pipe 62, and the baffle 69 blocks the channel of the feeding pipe 62 again, waiting for the next feeding instruction, so as to complete a complete feeding cycle.

[0036] Referring to Figure 2 As shown, the feeding pipe 62 is arranged obliquely, and the end of the feeding pipe 62 gradually inclines downward to the direction close to the center of the tank body 2. During the feeding of the device, the silk fibroin to be degummed enters from the higher end of the feeding pipe 62. Due to the gradual downward inclination of the feeding pipe 62 to the direction close to the center of the tank body 2, the silk fibroin automatically slides to the lower end of the feeding pipe 62 under the action of gravity. The use of gravity makes the feeding process of the silk fibroin more smooth and efficient, reduces the problem of poor feeding caused by material accumulation or blockage, and ensures the stable operation of the silk fibroin degumming device.

[0037] Referring to Figure 2 As shown, the projection areas of the cutter 66 and the baffle 69 in the height direction do not coincide, the distance between the baffle 69 and the center of the tank body 2 is less than the distance between the cutter 66 and the center of the tank body 2, the cutter 66 and the baffle 69 are staggered, avoiding mutual interference, and the baffle 69 is closer to the tank body 2, and the cutter 66 is closer to the outside, so that the cutter 66 directly contacts the silk fibroin to be cut, improving the cutting efficiency.

[0038] Referring to Figure 1As shown, the tank body 2 is provided with a support 5, the feeding pipe 62 is arranged on the support 5 and is inclined downwardly to the direction close to the tank body 2 through the feeding port 11, the top end of the feeding pipe 62 is provided with an outwardly expanded feeding bin 63, the output end of the second driving member 61 is connected with the cutter 66 and the baffle 69 through the lifting frame 64, the movement path of the lifting frame 64 does not interfere with the feeding pipe 62, the supporting rod of the lifting frame is provided with a guide sleeve 65 connected with the support 5, thereby improving the movement stability of the lifting frame 64. The feeding pipe 62 is provided with a cushion block 67, and the cutting groove 68 is arranged in the cushion block 67 and is adapted to the cutter 66. The feeding pipe 62 is respectively provided with through holes adapted to the movement of the cutter 66 and the baffle 69. In this embodiment, the cross section of the feeding pipe 62 is rectangular to adapt to the cutter 66 and the baffle 69.

[0039] Referring to Figure 3 As shown, the inner wall of the feeding pipe 62 is provided with the cutting groove 68, the cutter 66 is adapted to the cutting groove 68, the cutter 66 can be attached to the side wall of the cutting groove 68, thereby avoiding the cutter 66 damaging the feeding pipe 62. In this embodiment, the inner wall of the feeding pipe 62 is embedded with the cushion block 67, the cutting groove 68 is arranged in the cushion block 67, thereby preventing the cutter 66 from hard collision with the inner wall of the feeding pipe 62 during the cutting of the silk protein, avoiding the feeding pipe 62 being damaged due to the scratching and impact of the cutter 66, thereby prolonging the service life of the feeding pipe 62 and ensuring the stable operation of the feeding mechanism.

[0040] Referring to Figure 1 As shown, the tank body 2 is provided with the discharging disc 1, the discharging disc 1 is sealingly connected to the inner wall of the tank body 2. The discharging disc 1 and the tank body 2 define a stirring space for placing the silk protein and can accommodate the degumming liquid. In this embodiment, the degumming liquid is water and anhydrous sodium carbonate. The water can be added from the water inlet 3 or the feeding port 11, and the anhydrous sodium carbonate is added from the feeding port 11. Preferably, the water is added from the water inlet 3. The cut silk protein can be uniformly distributed on the discharging disc 1 and is stirred by the stirring paddle 10. The discharging disc 1 is sealingly connected to the inner wall of the tank body 2, thereby ensuring the sealing property of the stirring space and preventing the liquid and the material from leaking to other parts of the tank body 2 during the stirring. The material and the degumming liquid on the discharging disc 1 are gradually mixed with other substances in the stirring space under the stirring, thereby accelerating the degumming reaction.

[0041] Referring to Figure 1As shown, the feeding tray 1 is provided with a heating unit 13, which is arranged at the bottom of the tank body 2, and the tank body 2 is also provided with a control unit, and the first driving member 8, the second driving member 61 and the heating unit 13 are all electrically connected to the control unit. The first driving member 8 is a driving motor, which is connected to the stirring shaft 9 through a speed reducer 7, and the control unit adopts a programmable logic controller, which has the advantages of high reliability, strong flexibility, simple programming and the like, and can meet the complex control requirements of the silk protein degumming equipment. The control unit is installed in a control cabinet outside the tank body 2 and is electrically connected to the first driving member 8, the second driving member 61 and the heating unit 13 through wires. The control unit is used for controlling the first driving member, the second driving member and the heating unit.

[0042] After the chopped silk protein falls into the feeding tray 1, water and anhydrous sodium carbonate are added for the first time, and the first heating is performed. After heating for 10 minutes, the silk protein is added for degumming. Water and anhydrous sodium carbonate are added for the second time, and after heating for 30 minutes, the water is drained. Water and anhydrous sodium carbonate are added for the third time, and after heating for 30 minutes, the water is drained, so that the degummed silk protein is obtained.

[0043] With reference to Figure 1 As shown, the tank body 2 is also provided with a sampling port 12 communicating with the stirring space, so as to facilitate material taking. The tank body 2 is in an open state at the top and is provided with the sampling port 12 at the side for sampling, and does not affect the normal operation of the equipment and the reaction environment in the stirring space. The sampled sample can be used for laboratory analysis and detection, such as through chemical analysis, microscope observation and the like, to understand the degumming degree of the silk protein, the pH value of the solution, the component concentration and the like, and according to the detection result, the operator can adjust the degumming process, such as changing the stirring speed, the heating temperature, the addition amount of the degumming liquid and the like, so as to ensure that the degumming process proceeds in the expected direction, and finally the silk protein product meeting the quality requirements is obtained.

[0044] The height of the water inlet port 3 relative to the bottom of the tank body 2 is greater than the height of the water outlet port 4 relative to the bottom of the tank body 2, and the height of the feeding port 11 relative to the bottom of the tank body 2 is greater than the height of the sampling port 12 relative to the bottom of the tank body 2. The sampling port 12 at the lower position is convenient for obtaining a representative sample at a suitable stage. The water inlet port 3, the water outlet port 4 and the sampling port 12 are all provided with valves or gates for controlling the opening and closing and size of the water inlet port 3, the water outlet port 4 and the sampling port 12.

[0045] Obviously, the above embodiments are only examples for clearly illustrating, and are not limited to the embodiments. For those skilled in the art, other different forms of changes or variations can be made on the basis of the above description. Here, all the embodiments are not required to be exhausted, and the obvious changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A silk protein degumming device, characterized in that, include: The tank body encloses a stirring space, and the tank body is respectively provided with a feed inlet, a water inlet and a water outlet connected to the stirring space; A stirring mechanism includes: a first driving member, a stirring shaft, and a stirring paddle, wherein the stirring paddle is located within a stirring space and is connected to the stirring shaft, and the stirring shaft is connected to the output end of the first driving member; The feeding mechanism includes a feeding pipe, a cutter, a baffle, and a second driving component. The feeding pipe is disposed at the feeding port and connected to the stirring space. The cutter is disposed on the first side of the feeding pipe, and the baffle is disposed on the second side of the feeding pipe. Both the cutter and the baffle are connected to the output end of the second driving component.

2. The silk fibroin degumming equipment according to claim 1, characterized in that: The second driving component is a linear driving component, and the feed pipe is respectively provided with a first clearance hole and a second clearance hole adapted to the cutter and the baffle.

3. The silk fibroin degumming equipment according to claim 1, characterized in that: The cutter and baffle are driven by a second drive member in the height direction and / or the horizontal direction.

4. The silk fibroin degumming equipment according to claim 1, characterized in that: The feed pipe is inclined, and the end of the feed pipe gradually slopes downward toward the center of the tank.

5. The silk fibroin degumming equipment according to claim 4, characterized in that: The projection areas of the cutter and the baffle along the height direction do not coincide, and the distance between the baffle and the center of the tank is less than the distance between the cutter and the center of the tank.

6. The silk fibroin degumming equipment according to claim 1, characterized in that: The inner wall of the feed pipe is provided with a cutting groove, and the cutter is adapted to the cutting groove.

7. The silk fibroin degumming equipment according to claim 6, characterized in that: The tank is equipped with a discharge tray, which is sealed to the inner wall of the tank.

8. The silk fibroin degumming equipment according to claim 7, characterized in that: A heating unit is provided on one side of the feeding tray, and a control unit is also provided in the tank. The first driving component, the second driving component, and the heating unit are all electrically connected to the control unit.

9. The silk fibroin degumming equipment according to claim 1, characterized in that: The tank is also equipped with a sampling port that connects to the stirring space.

10. A silk fibroin degumming device according to claim 8, characterized in that: The height of the water inlet relative to the bottom of the tank is greater than the height of the water outlet relative to the bottom of the tank, and the height of the feed inlet relative to the bottom of the tank is greater than the height of the sampling inlet relative to the bottom of the tank.

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