A large animal disposable combined blood sampling device

Abstract

The application relates to the technical field of blood sampling devices for large animals, and discloses a disposable combined blood sampling device for large animals, which comprises a large-capacity storage bag, a sheet clamp, a first funnel, a sample storage bag, a male luer connector, a nine-way connector, a second funnel, a large-capacity blood sampling bag and a blood sampling assembly. The device is designed in an integrated mode, and the operation convenience is obviously improved; the multiple large-capacity blood sampling bags are connected in parallel through the nine-way connector and are connected to the large-capacity storage bag through a flow guide pipe, so that the blood sampling, filtering and mixing processes are completed at one time in a closed system, and the blood sampling bag does not need to be frequently replaced or assisted by external tools; in addition, the blood sampling assembly optimizes the blood flow path in combination with the second funnel and a buffer pipe, and can realize rapid and uniform blood sampling in cooperation with a peristaltic pump, and the efficiency is obviously improved compared with a traditional natural gravity flow mode.

Description

Technical Field

[0001] This invention relates to the field of blood collection devices for large animals, specifically a single-use combined blood collection device for large animals. Background Technology

[0002] In the field of blood collection from large animals (such as cattle and sheep), the conventional practice is to use multiple standard blood collection bags with smaller capacities (such as 200ml or 400ml) connected in series or parallel. This traditional method has several significant drawbacks:

[0003] First, because large animals have a large total blood volume, using small-capacity blood collection bags requires frequent changes or multiple venipunctures. Each puncture increases the complexity of the procedure, animal stress, and the risk of blood contamination. Furthermore, using multiple small-capacity blood collection bags means that subsequent blood processing requires mixing the blood from each bag. This mixing process often needs to be carried out in an open or semi-open environment (such as a sterile workbench) with the aid of additional filtration equipment, significantly increasing the probability of blood exposure to the external environment and thus contamination.

[0004] Secondly, existing small-capacity blood collection bags have relatively limited functionality and simple internal structures, typically lacking efficient and integrated filtration and buffering modules. During blood collection, blood relies on natural gravity flow, which is inefficient and makes it difficult to effectively separate solid fibrin and microclots from the blood during collection. This necessitates additional filtration before blood use, increasing operational steps and time costs, and further enhancing the risk of contamination.

[0005] Furthermore, from a quality control and economic cost perspective, blood from the same animal, being packaged in multiple small bags, requires repeated testing, increasing workload. The same total volume of blood requires more blood bags, which also means higher packaging, sterilization, and logistics costs. Summary of the Invention

[0006] (a) Technical problems to be solved

[0007] To overcome the aforementioned deficiencies of the prior art, the present invention provides a single-use combined blood collection device specifically for large animals.

[0008] (II) Technical Solution

[0009] To achieve the above objectives, the present invention provides the following technical solution: a single-use combined blood collection device specifically for large animals, comprising a large-capacity storage bag, a clip, a first funnel, a sample retention bag, a male Luer connector, a nine-way connector, a second funnel, a large-capacity blood collection bag, and a blood collection assembly; the large-capacity blood collection bag comprises multiple bags, each connected to a secondary tube of the nine-way connector via a guide tube, and the main tube of the nine-way connector is connected to the large-capacity storage bag via an inlet tube; the sample retention bag is connected to a shunt head of the inlet tube via a shunt tube; the first funnel is positioned in the path of the inlet tube, and the second funnel is positioned in the blood collection path of each large-capacity blood collection bag; the clip is held in place on the pipe to control blood flow; the male Luer connector is connected to the end of the discharge tube of the large-capacity storage bag; the blood collection assembly is positioned at the inlet end of each large-capacity blood collection bag for puncture and blood collection.

[0010] Optionally, the large-capacity storage bag is provided with a hanging hole at the top for hanging and fixing; a diversion head is provided at the inlet of the inlet blood vessel for connecting to the diversion tube; a hemostatic head is provided at the end of the outlet blood vessel for controlling the outflow of blood; and a filter cotton is provided inside the inlet blood vessel for filtering impurities in the blood.

[0011] Optionally, the clamp is provided with a pipe placement hole and a pipe gathering hole. The pipe placement hole is used to place and fix the pipe, and the pipe gathering hole is used to gather multiple pipes and control their opening and closing through a clamping mechanism.

[0012] Optionally, the first funnel includes a connector and a filter element. The connector is used to connect to the blood vessel, and the filter element has a built-in filter screen for preliminary filtration of the blood.

[0013] Optionally, the sample retention bag is connected to a shunt tube, which is equipped with a blood discharge head for sampling blood.

[0014] Optionally, the male Luer connector includes an interface, a knob connector, and a rubber protective sleeve. The interface connects to the drain tube, the knob connector is used for rotating docking with external equipment, and the rubber protective sleeve is used to protect the connector from contamination.

[0015] Optionally, the nine-way connector includes a main pipe and multiple secondary pipes. The main pipe is connected to the inlet blood vessel, and the secondary pipes are respectively connected to the guide tubes of each blood collection bag to realize the collection of multiple blood streams.

[0016] Optionally, the large-capacity blood collection bag is equipped with a sampling tube, an infusion tube, a buffer tube, and a cable tie. The sampling tube is used for sampling and testing, the infusion tube is connected to the blood collection assembly, the buffer tube reduces the impact of blood flow, and the cable tie is used to fix and organize the tubing.

[0017] Optionally, the blood collection assembly includes a blood collection needle, a protective outer sheath, and a protective inner sheath. The blood collection needle is used to puncture animal blood vessels, and the protective outer sheath and the protective inner sheath together provide sterile protection.

[0018] (III) Beneficial Effects

[0019] This invention provides a single-use combined blood collection device specifically for large animals, which has the following beneficial effects:

[0020] 1. This device adopts an integrated design, significantly improving ease of operation. Multiple large-capacity blood collection bags are connected in parallel via a nine-way connector and then connected to a large-capacity storage bag via a guide tube. This allows the blood collection, filtration, and mixing processes to be completed in a closed system in one go, eliminating the need for frequent blood bag replacements or external tools. In addition, the blood collection component, combined with a second funnel and buffer tube, optimizes the blood flow path. When used with a peristaltic pump, it can achieve rapid and uniform blood collection, significantly improving efficiency compared to traditional gravity flow. Furthermore, the clip design simplifies pipeline control, and the pipeline placement hole and converging hole facilitate quick clamping or opening of the pipeline, reducing operational steps. The independent setting of the sample retention bag and the diversion tube allows for sampling and testing without stopping blood collection, further saving time. The overall device has a compact structure, easy-to-fix hanging holes, and plug-and-play Luer connectors, greatly reducing the labor intensity and skill requirements of operators. It is suitable for non-laboratory environments such as field or farms.

[0021] 2. This device boasts significant advantages in preventing contamination. All components undergo irradiation sterilization before leaving the factory, ensuring a sterile state. Blood collection is conducted entirely within a closed pipeline system, with blood only contacting the internal sterile surfaces, completely preventing contact with the external environment. The first and second funnels contain built-in filters and filtration structures, effectively intercepting fibrin and clots. Filter cotton further purifies the blood, and all filtration steps are completed within the system, eliminating the need for open operation. The design of the nine-way connector and multi-channel diversion tubes allows each blood bag to operate independently. If a bag of blood fails inspection, it can be partially removed through the blood outlet of the diversion tube without affecting other qualified blood, greatly reducing the risk of cross-contamination. The double-layer protective sleeve of the blood collection components ensures that the needle remains sterile before use, and the rubber protective sleeve of the Luer connector prevents interface contamination. This fully enclosed, modular design not only meets GMP standards but also reduces the possibility of contamination introduced by human operation, ensuring the quality and safety of blood products. Attached Figure Description

[0022] Figure 1 This is a schematic diagram of the structure of the present invention;

[0023] Figure 2 This is a schematic diagram of the structure of the large-capacity storage bag of the present invention;

[0024] Figure 3 This is a schematic diagram of the sample retention bag of the present invention;

[0025] Figure 4 This is a schematic diagram of the structure of the first funnel and the Luer connector of the present invention;

[0026] Figure 5 This is a schematic diagram of the nine-way connector of the present invention;

[0027] Figure 6 This is a schematic diagram of the structure of the second funnel and the large-capacity blood collection bag of the present invention;

[0028] Figure 7 This is an exploded view of the blood collection assembly of the present invention;

[0029] Figure 8 This is a schematic diagram of the structure of the clip of the present invention.

[0030] In the diagram: 1. Large-capacity storage bag; 2. Slip clip; 3. First funnel; 4. Sample retention bag; 5. Luer connector; 6. Nine-way connector; 7. Second funnel; 8. Large-capacity blood collection bag; 9. Blood collection assembly; 11. Suspension hole; 12. Drainage tube; 13. Inlet tube; 14. Filter cotton; 121. Hemostatic head; 131. Diverter head; 21. Tube placement hole; 22. Tube retraction hole; 31. Connector; 32. Filter element; 41. Diverter tube; 42. Drainage head; 51. Interface; 52. Knob connector; 53. Rubber protective sleeve; 61. Main tube; 62. Secondary tube; 81. Sampling tube; 82. Infusion tube; 83. Buffer tube; 84. Cable tie; 91. Blood collection needle; 92. Protective outer sleeve; 93. Protective inner sleeve. Detailed Implementation

[0031] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0032] To make the technical means, creative features, objectives, and effects of this invention easier to understand, the following is a summary... Figures 1 to 8 The present invention will be further described below.

[0033] This invention provides a technical solution: a single-use combined blood collection device for large animals, comprising a large-capacity storage bag 1, a clip 2, a first funnel 3, a sample retention bag 4, a male Luer connector 5, a nine-way connector 6, a second funnel 7, a large-capacity blood collection bag 8, and a blood collection assembly 9.

[0034] Example 1:

[0035] Multiple large-capacity blood collection bags 8 are included, each connected to a secondary tube 62 of a nine-way connector 6 via a guide tube. The main tube 61 of the nine-way connector 6 is connected to the large-capacity storage bag 1 via an inlet tube 13. The large-capacity storage bag 1 has a hanging hole 11 at its top for hanging and fixing. A shunt head 131 is provided at the inlet of the inlet tube 13 for connecting to a shunt tube 41. A hemostatic head 121 is provided at the end of the outlet tube 12 for controlling blood outflow. A filter cotton 14 is provided inside the inlet tube 13 for filtering impurities in the blood. The nine-way connector 6 includes a main tube 61 and multiple secondary tubes 62. The main tube 61 is connected to the inlet tube 13, and the secondary tubes 62 are respectively connected to the guide tubes of each blood collection bag to achieve multi-channel blood collection. The large-capacity blood collection bag 8 is equipped with a collection... The device includes a sample tube 81, an infusion tube 82, a buffer tube 83, and a cable tie 84. The sample tube 81 is used for sampling and testing; the infusion tube 82 connects to the blood collection assembly 9; the buffer tube 83 reduces blood flow impact; and the cable tie 84 is used to secure and organize the tubing. A large-capacity storage bag 1 serves as the terminal container for the entire device, collecting and ultimately storing all qualified blood collected from each blood collection bag. A suspension hole 11 is used to suspend and fix the entire device or component, utilizing gravity to assist the natural flow of blood. An outlet tube 12 serves as the output pipe of the storage bag; blood flows out through this pipe during final processing or use. An inlet tube 13 serves as the input pipe of the storage bag; all qualified blood flows into the main storage bag through this pipe. A filter cotton 14 is built-in. The deep filter medium at the inlet of the drain tube 12 or storage bag is used to filter out finer solid particles and fibrin in the blood; the hemostatic head 121, located at the end of the drain tube 12, is a bendable tubular item, normally connected for hemostasis. When the user needs to drain blood from the large-capacity storage bag 1, the hemostatic head 121 can be bent to allow blood flow; the shunt head 131 is a branch point on the inlet tube 13, used to connect to the sample retention bag 4; the nine-way connector 6 is the core connection hub of the device, which gathers the tubing of multiple blood collection bags into a main pipeline, realizing multi-in-one blood confluence; the main pipe 61 is the main output pipe of the nine-way connector 6, connected to the large-capacity storage bag 1; the secondary pipe 62 is the nine-way connector 6... The connector 6 has multiple branch input pipes that connect to each large-capacity blood collection bag 8. The large-capacity blood collection bag 8 serves as the initial blood collection unit. Its large-capacity design reduces the number of bag replacements, and each bag works independently, allowing for individual testing and processing. The sampling tube 81 is a thin tube extending from a single blood collection bag, used to collect blood samples for testing without affecting the main bag. The infusion tube 82 is the main pipe connecting the blood collection assembly 9 and the blood collection bag, through which blood flows into the bag. The buffer tube 83 is a flexible tube with a certain volume, used to alleviate blood flow pulsations and make blood flow more stable. The cable tie 84 is used to fix and organize multiple pipes, preventing them from tangling and keeping the device clean and easy to operate.

[0036] Example 2:

[0037] The sample retention bag 4 is connected to the shunt head 131 of the inlet blood vessel 13 via the shunt tube 41; the first funnel 3 is set in the path of the inlet blood vessel 13, and the second funnel 7 is set in the blood collection path of each large-capacity blood collection bag 8; the first funnel 3 includes a connector 31 and a filter element 32, the connector 31 is used to connect to the inlet blood vessel 13, and the filter element 32 has a built-in filter screen for preliminary filtration of blood; the sample retention bag 4 is connected to the shunt tube 41, and the shunt tube 41 is equipped with a blood discharge head 42 for sampling blood; the clip 2 is a pipeline switch controller, which controls the flow and interruption of blood in a specific pipeline by clamping or releasing the pipeline, thereby realizing segmented control; The tube placement hole 21 is a groove or hole on the clip 2 for accommodating and fixing the tube; the tube collection hole 22 is a mechanism on the clip 2 for concentrating and clamping multiple tubes together; the male Luer connector 5, as a standardized, leak-proof sterile interface 51, connects the storage bag to external infusion or processing equipment to ensure a safe and closed blood transfer process; the interface 51 is the base part connecting the male Luer connector to the drain tube 12; the knob connector 52 is the operating part of the male Luer connector that enables quick, sealed, and locking connection with the female Luer connector; the rubber protective sleeve 53 is put on the male Luer connector before use to maintain the sterility of its interface 51 and prevent contamination.

[0038] Example 3:

[0039] Clip 2 is held onto the tube to control blood flow; male Luer connector 5 is connected to the end of the drain tube 12 of the large-capacity storage bag 1; clip 2 is provided with a tube placement hole 21 and a tube constriction hole 22. The tube placement hole 21 is used to place and fix the tube, and the tube constriction hole 22 is used to constrict multiple tubes and control their opening and closing through a clamping mechanism; male Luer connector 5 includes an interface 51, a knob connector 52, and a rubber protective sleeve 53. The interface 51 is connected to the drain tube 12, the knob connector 52 is used for rotating and docking with external equipment, and the rubber protective sleeve 53 is used to protect the connector from contamination; the first funnel 3 is located on the path of the main inlet tube 13, and its main function is to collect and finally filter the blood, ensuring that the blood entering the storage bag is of high quality. The blood is purified; connector 31 is used to reliably connect the funnel to the piping system; filter element 32 is a filter screen installed inside the funnel and is the core part for performing physical filtration; sample retention bag 4 is used to collect a small amount of blood sample before the blood flows into the main storage bag for quality inspection, avoiding contamination of the main blood bag; diversion tube 41 is a pipe connecting diversion head 131 and sample retention bag 4 or waste liquid bag, used to guide part of the blood flow; blood drain head 42 is located at the top of sample retention bag 4 and is used to drain the blood in sample retention bag 4; second funnel 7 is set at the inlet of each blood collection bag to receive the blood flowing out of the animal and perform preliminary filtration to remove larger impurities and air bubbles.

[0040] Example 4:

[0041] The blood collection assembly 9 is located at the inlet end of each large-capacity blood collection bag 8 and is used for puncture blood collection. The blood collection assembly 9 includes a blood collection needle 91, a protective outer sheath 92, and a protective inner sheath 93. The blood collection needle 91 is used to puncture the animal's blood vessel, and the protective outer sheath 92 and the protective inner sheath 93 together provide sterile protection. The blood collection assembly 9 is the core component for performing venous puncture and is responsible for puncturing the animal's blood vessel to establish a channel for blood outflow. The blood collection needle 91 is the sharp instrument part that directly performs vascular puncture. The protective outer sheath 92 is used to protect the needle body from contamination before blood collection and to safely wrap the used needle tip after blood collection to prevent needlestick injuries. The protective inner sheath 93 is an initial sterile sealing protective sleeve that ensures the sterility of the needle tip before use.

[0042] All electrical components mentioned in this article are connected to an external main controller and 220V AC mains power, and the main controller can be a conventional known device such as a computer that can control it.

[0043] The working steps of the device in this invention are as follows:

[0044] First, fix the device in a suitable position through the hanging hole 11, check whether the pipe connections are sealed, and open the clip 2 to make the pipes unobstructed; second, puncture the blood collection needle 91 of the blood collection component 9 into the blood vessel of the large animal, start the external peristaltic pump, and the blood flows into the large-capacity blood collection bag 8 after preliminary filtration through the second funnel 7, and is sampled and tested in real time through the sampling tube 81; then, if the blood is qualified, keep it flowing, and if it is not qualified, close the corresponding pipe through the clip 2; finally, the qualified blood is collected through the guide tube to the nine-way connector 6, enters the large-capacity storage bag 1 through the inlet tube 13, and is finally filtered through the first funnel 3 and the filter cotton 14, and is connected to the external equipment through the Luer connector 5 to complete the entire blood collection process.

[0045] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A single-use combined blood collection device specifically for large animals, characterized in that, The system includes a large-capacity storage bag (1), a clip (2), a first funnel (3), a sample retention bag (4), a Luer connector (5), a nine-way connector (6), a second funnel (7), a large-capacity blood collection bag (8), and a blood collection assembly (9). Multiple large-capacity blood collection bags (8) are included, each connected to the secondary tube (62) of the nine-way connector (6) via a guide tube. The main tube (61) of the nine-way connector (6) is connected to the large-capacity storage bag (1) via an inlet tube (13). The sample retention bag (4) is connected to the large-capacity storage bag (1) via a branch tube. The flow tube (41) is connected to the shunt head (131) of the inlet tube (13); the first funnel (3) is set in the path of the inlet tube (13), and the second funnel (7) is set in the blood collection path of each large-capacity blood collection bag (8); the clip (2) is clamped on the tube to control the blood flow; the Luer connector (5) is connected to the end of the drain tube (12) of the large-capacity storage bag (1); the blood collection assembly (9) is set at the inlet end of each large-capacity blood collection bag (8) for puncture blood collection.

2. The device for single-use combined blood collection of large animals according to claim 1, characterized in that: The large-capacity storage bag (1) has a hanging hole (11) at the top for hanging and fixing; the inlet of the inlet tube (13) has a diversion head (131) for connecting the diversion tube (41); the outlet tube (12) has a hemostatic head (121) at the end for controlling the outflow of blood; the inlet tube (13) has a filter cotton (14) inside for filtering impurities in the blood.

3. The device for single-use combined blood collection of large animals according to claim 1, characterized in that: The clip (2) is provided with a pipe placement hole (21) and a pipe gathering hole (22). The pipe placement hole (21) is used to place and fix the pipe, and the pipe gathering hole (22) is used to gather multiple pipes and control their opening and closing through a clamping mechanism.

4. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The first funnel (3) includes a connector (31) and a filter element (32). The connector (31) is used to connect to the blood inlet (13), and the filter element (32) has a built-in filter screen for preliminary filtration of blood.

5. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The sample retention bag (4) is connected to the shunt tube (41), and the shunt tube (41) is equipped with a blood discharge head (42) for taking blood samples.

6. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The male Luer connector (5) includes an interface (51), a knob connector (52), and a rubber protective sleeve (53). The interface (51) is connected to the drain tube (12), the knob connector (52) is used to rotate and dock with external equipment, and the rubber protective sleeve (53) is used to protect the connector from contamination.

7. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The nine-way connector (6) includes a main pipe (61) and multiple secondary pipes (62). The main pipe (61) is connected to the inlet blood vessel (13), and the secondary pipes (62) are respectively connected to the guide tubes of each blood collection bag to realize the collection of multiple blood streams.

8. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The large-capacity blood collection bag (8) is equipped with a sampling tube (81), an infusion tube (82), a buffer tube (83), and a cable tie (84). The sampling tube (81) is used for sampling and testing, the infusion tube (82) is connected to the blood collection assembly (9), the buffer tube (83) reduces the impact of blood flow, and the cable tie (84) is used to fix and organize the tubing.

9. A single-use combined blood collection device for large animals according to claim 1, characterized in that: The blood collection assembly (9) includes a blood collection needle (91), a protective outer sheath (92) and a protective inner sheath (93). The blood collection needle (91) is used to puncture animal blood vessels, and the protective outer sheath (92) and the protective inner sheath (93) together provide sterile protection.

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