Bag

Abstract

To reduce a dead volume of a bag.SOLUTION: A bag according to an embodiment includes a housing part, a discharging part, and a discharging pipe. The housing part has a housing chamber that houses a liquid being a sample or a reagent. The discharging part has a discharging path for discharging the liquid from the housing chamber. The discharging pipe is connected to the discharging part, and discharges the liquid from the housing chamber via the discharging path. The discharging pipe is connected to the discharging part to extend from the discharging part toward a direction having a horizontal direction component.SELECTED DRAWING: Figure 1

Description

[Technical Field]

[0001] The embodiments disclosed in this specification and drawings relate to a bag. [Background technology]

[0002] Conventionally, in producing induced pluripotent stem cells (hereinafter referred to as iPS (induced pluripotent stem) cells), for example, samples and reagents are supplied from multiple bags to a cell production device.

[0003] The bag containing the sample or reagent may be made of, for example, a soft material. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] Japanese Patent Publication No. 2020-195576 Summary of the Invention [Problem to be solved by the invention]

[0005] One of the problems to be solved by the embodiments disclosed in this specification and the drawings is to reduce the dead volume of the bag. However, the problems to be solved by the embodiments disclosed in this specification and the drawings are not limited to the above problem. Problems corresponding to the effects of each configuration shown in the embodiments described below can also be positioned as other problems. [Means for solving the problem]

[0006] The bag according to the embodiment includes a storage section, a discharge section, and a discharge pipe. The storage section has a storage chamber that stores a liquid such as a sample or a reagent. The discharge section has a discharge path for discharging the liquid from the storage chamber. The discharge pipe is connected to the discharge section and discharges the liquid from the storage chamber via the discharge path. The discharge pipe is connected to the discharge section so as to extend from the discharge section in a direction having a horizontal component. [Brief explanation of the drawings]

[0007] [Figure 1] FIG. 1 is a front view showing an outline of a bag according to an embodiment. [Figure 2] FIG. 2 is a bottom view showing an outline of the bag according to the embodiment. [Figure 3] FIG. 3 is a front view showing an outline of the main body according to the embodiment. [Figure 4] FIG. 4 is a schematic view of the main body portion taken along the line IV-IV in FIG. [Figure 5] FIG. 5 is a front view showing an outline of a bag according to a modified example. DETAILED DESCRIPTION OF THE INVENTION

[0008] The bag will be described below with reference to the drawings. In the following embodiments, parts with the same reference numerals perform similar operations, and redundant explanations will be omitted as appropriate. In addition, the content described in one embodiment is, in principle, also applicable to the modified examples.

[0009] The bag according to the embodiment is, for example, a bag containing a sample or a liquid reagent for producing iPS cells. For example, a cartridge for producing iPS cells contains multiple bags, and the cartridge is installed in an iPS cell production apparatus. When producing iPS cells, samples and reagents are supplied to the cartridge from the multiple bags. Each bag is connected to a closed flow path contained in the cartridge. The liquid contained in each bag is introduced into the closed flow path and used to produce iPS cells. At this time, a driving force is required to introduce the liquid into the closed flow path. For example, the iPS cell production apparatus is connected to the cartridge, and this driving force is supplied by applying negative pressure to the closed flow path within the cartridge. The cartridge for producing iPS cells is an example of a unit separate from the bag.

[0010] The sample is, for example, human blood. The reagent is, for example, a reagent necessary for producing iPS cells. Since known reagents can be applied to the reagents necessary for producing iPS cells, a description thereof will be omitted.

[0011] The amount of sample and reagent used when producing iPS cells is, for example, several milliliters to several tens of milliliters. Therefore, for example, a small amount of sample or reagent is contained in the bag. Note that the liquid contained in the bag is not limited to the sample or reagent for producing iPS cells.

[0012] In the following, the vertical direction is referred to as the up-down direction, the thickness direction of the bag among the directions (horizontal directions) perpendicular to the up-down direction is referred to as the front-to-back direction, and the direction perpendicular to the up-down direction and the front-to-back direction is referred to as the left-to-right direction.

[0013] A bag 1 according to an embodiment will be described with reference to Figs. 1 to 4. Fig. 1 is a front view showing an outline of the bag 1 according to the embodiment. Fig. 2 is a bottom view showing an outline of the bag 1 according to the embodiment. Fig. 3 is a front view showing an outline of the main body 2 according to the embodiment. Fig. 4 is a diagram showing an outline of the main body 2 in the cross section taken along line IV-IV in Fig. 3. In each figure, some hidden lines are indicated by dashed lines.

[0014] As shown in FIGS. 1 and 2, the bag 1 includes a main body 2, a discharge pipe 3, a connector 4, and a holder 5.

[0015] As shown in FIG. 3, the main body 2 includes a storage section 10, a discharge section 11, a filling section 12, a biasing section 13, a cylindrical member 14, and a sealing section 15.

[0016] As shown in FIG. 4, the storage section 10 is formed by joining a portion of the first sheet 100 and a portion of the second sheet 101. A peripheral edge 2a is formed around the storage section 10. The peripheral edge 2a is the area where the first sheet 100 and the second sheet 101 are joined. Each sheet 100, 101 is made of a soft material. The material of each sheet 100, 101 is selected according to the type of liquid to be stored in the bag 1. The material of each sheet 100, 101 is a material that does not react with the components of the liquid to be stored in the bag 1 and a material that does not adsorb the components of the liquid to be stored in the bag 1. The same applies to the other members used in the bag 1.

[0017] The storage unit 10 has a storage chamber 10a. A sample or a liquid such as a reagent is stored in the storage chamber 10a. The storage chamber 10a is formed by a peripheral wall portion 10b and a side wall portion 10c.

[0018] The peripheral wall portion 10b is formed to rise from the peripheral edge portion 2a. The peripheral wall portion 10b formed on the first sheet 100 is formed to rise from the peripheral edge portion 2a toward the front. The peripheral wall portion 10b formed on the second sheet 101 is formed to rise from the peripheral edge portion 2a toward the rear.

[0019] The side wall 10c is formed to connect to the end of the peripheral wall 10b opposite the peripheral edge 2a. That is, the peripheral wall 10b and the side wall 10c formed on the first sheet 100 are formed to protrude forward. The peripheral wall 10b and the side wall 10c formed on the second sheet 101 are formed to protrude rearward.

[0020] In this way, the storage section 10 is formed to protrude outward. The "outward" refers to the side of the first sheet 100 and the second sheet 101 opposite to the side where the liquid is present when the liquid is stored in the storage chamber 10a.

[0021] 3, the bottom 10d of the storage chamber 10a is inclined downward. The bottom 10d of the storage chamber 10a is inclined toward the discharge portion 11. For example, the bottom 10d of the storage chamber 10a is inclined so that it is positioned lower toward the right.

[0022] The discharge section 11 is provided below the storage section 10. The discharge section 11 is provided on the end side of the storage section 10 in the left-right direction. For example, the discharge section 11 is provided on the right end side of the storage section 10. The discharge section 11 is provided so as to protrude downward from the storage section 10.

[0023] Discharge section 11 is formed by joining a part of first sheet 100 and a part of second sheet 101 (see FIG. 4). Storage section 10 and discharge section 11 are integrally formed.

[0024] The discharge section 11 has a discharge path 11a. The discharge path 11a is connected to the lower end of the storage chamber 10a. The discharge path 11a is formed to extend downward from the lower end of the storage chamber 10a. The discharge path 11a is a flow path for discharging liquid from the storage chamber 10a. The volume of the discharge path 11a is smaller than the volume of the storage chamber 10a.

[0025] As shown in FIG. 4, the discharge path 11a is formed by a peripheral wall portion 11b and a side wall portion 11c.

[0026] The peripheral wall portion 11b is formed to rise from the peripheral edge portion 2a. The peripheral wall portion 11b formed on the first sheet 100 is formed to rise from the peripheral edge portion 2a toward the front. The peripheral wall portion 11b formed on the second sheet 101 is formed to rise from the peripheral edge portion 2a toward the rear.

[0027] The side wall portion 11c is formed so as to connect to the end of the peripheral wall portion 11b on the opposite side from the peripheral edge portion 2a. That is, the peripheral wall portion 11b and the side wall portion 11c formed on the first sheet 100 are formed so as to protrude forward. The peripheral wall portion 11b and the side wall portion 11c formed on the second sheet 101 are formed so as to protrude rearward. In this way, the discharge portion 11 is formed so as to protrude outward.

[0028] The discharge portion 11 also includes a connection joint 11d. As shown in FIG. 3, the connection joint 11d is provided on the lower end side of the discharge portion 11. The connection joint 11d is provided on the left end of the discharge portion 11. A portion of the connection joint 11d is joined to the first sheet 100 and the second sheet 101. The connection joint 11d protrudes in a direction having a horizontal component. In other words, the connection joint 11d protrudes in a direction intersecting the vertical direction. Specifically, a portion of the connection joint 11d protrudes toward the left. The connection joint 11d may be provided so as to be inclined upward and downward relative to the horizontal direction. A flow path is formed in the connection joint 11d. The flow path is connected to the discharge path 11a.

[0029] The filling section 12 is formed to extend downward from the storage section 10. The filling section 12 is provided on the end side in the left-right direction. For example, the filling section 12 is provided on the left end side of the storage section 10. In other words, the filling section 12 is provided on the opposite side of the discharge section 11 in the left-right direction. For example, the lower end of the filling section 12 is provided on an imaginary line extending the lower end of the discharge section 11 in the left-right direction.

[0030] The filling section 12 is formed by joining a portion of the first sheet 100 and a portion of the second sheet 101 (see FIG. 4). That is, the storage section 10 and the filling section 12 are integrally formed. The filling section 12 is formed so that the liquid is filled into the storage chamber 10a from the bottom 10d of the storage chamber 10a. The filling section 12 has a filling path 12a. The filling path 12a is a flow path for filling the storage chamber 10a with the liquid. The filling path 12a is formed, for example, to extend in the vertical direction.

[0031] The biasing portion 13 is accommodated in the storage chamber 10a. The biasing portion 13 is, for example, a leaf spring. Specifically, as shown in FIG. 4, the biasing portion 13 is formed to have a substantially V-shape in side view. When liquid is discharged from the storage chamber 10a, the biasing portion 13 biases the side wall portion 10c of the storage portion 10 that forms the storage chamber 10a outward. Specifically, when liquid is discharged from the storage chamber 10a, the biasing portion 13 biases the side wall portion 10c of the storage portion 10 that forms the storage chamber 10a in the front-to-rear direction. The repulsive force of the biasing portion 13 is set so that the biasing portion 13 closes when the liquid in the storage chamber 10a is discharged and the pressure in the storage chamber 10a becomes lower than atmospheric pressure.

[0032] The tubular member 14 is accommodated in the discharge path 11a. The tubular member 14 is formed, for example, in a cylindrical shape. The tubular member 14 is formed, for example, so as to extend in the up-down direction. The tubular member 14 is provided so as not to block the discharge path 11a when liquid is discharged from the storage chamber 10a. For example, the tubular member 14 is provided so as not to collapse in the front-to-back direction even when the liquid is discharged from the storage chamber 10a and the pressure in the discharge path 11a becomes lower than atmospheric pressure.

[0033] As shown in FIG. 3, the seal portion 15 is provided on the upper end side of the filling passage 12a. The seal portion 15 is formed by closing the filling passage 12a after the storage chamber 10a is filled with liquid. The seal portion 15 is formed, for example, by joining a first sheet 100 and a second sheet 101. The seal portion 15 blocks communication between the filling passage 12a and the storage chamber 10a after the storage chamber 10a is filled with liquid. The seal portion 15 is formed so as to fit along the bottom 10d of the storage chamber 10a. It is desirable that the upper end of the seal portion 15 is formed on the same straight line as the bottom 10d of the storage chamber 10a.

[0034] As shown in FIG. 1 , the discharge pipe 3 connects the discharge unit 11 and the connector 4. The discharge pipe 3 discharges liquid from the storage chamber 10a via the discharge path 11a. The discharge pipe 3 is connected to the discharge unit 11 so as to extend from the discharge unit 11 in a direction having a horizontal component. The discharge pipe 3 is also provided so as to extend from the discharge unit 11 in a direction having a horizontal component, and then extend upward toward the connector 4. That is, the discharge pipe 3 is formed in a substantially L-shape when viewed from the front.

[0035] The discharge pipe 3 includes a first tube 20, a second tube 21, and a joint 22. The first tube 20 is connected to the discharge section 11. Specifically, one end of the first tube 20 is connected to a connection joint 11d of the discharge section 11. The first tube 20 is provided to extend from the connection joint 11d in a direction having a horizontal component. For example, the first tube 20 is provided to extend leftward from the connection joint 11d. Note that the first tube 20 may be provided to be inclined vertically relative to the horizontal direction. The other end of the first tube 20 is connected to a first connection joint 22a of the joint 22.

[0036] The joint 22 connects the first tube 20 and the second tube 21. The joint 22 is formed in a substantially L-shape. A flow path is formed in the joint 22. The joint 22 changes the flow direction of the liquid flowing in from the first tube 20 to an upward direction. The joint 22 includes a first connection joint 22a and a second connection joint 22b.

[0037] The first tube 20 is connected to the first connection joint 22a, and the second tube 21 is connected to the second connection joint 22b.

[0038] The second tube 21 is connected to the connector 4. One end of the second tube 21 is connected to the underside of the connector 4. Specifically, one end of the second tube 21 is connected to a connection joint 4b provided on the underside of the connector 4. The second tube 21 is provided to extend downward from the underside of the connector 4. For example, the second tube 21 is provided to extend in the vertical direction from the underside of the connector 4. The second tube 21 may be provided to be inclined with respect to the vertical direction from the underside of the connector 4. The other end of the second tube 21 is connected to the second connection joint 22b of the joint 22.

[0039] The connector 4 connects the discharge pipe 3 to the external connector 40. The connector 4 allows the liquid to flow from the discharge pipe 3 into the external connector 40. The connector 4 is a sterile connector. The external connector 40 is connected to a closed tube 41 that supplies the liquid to a cartridge for producing iPS cells, which is a separate unit. The external connector 40 is a sterile connector.

[0040] The holder 5 holds the main body 2 and the connector 4. That is, the holder 5 holds the storage section 10, the discharge section 11, and the connector 4. The holder 5 includes a first holding section 30 and second holding sections 31 and 32. The first holding section 30 holds the main body 2. The first holding section 30 has an open upper end. A portion of the main body 2 and a portion of the discharge pipe 3 are inserted into the first holding section 30. Specifically, a portion of the storage section 10, the discharge section 11, and the filling section 12 are inserted into the first holding section 30. In addition, a portion of the first tube 20 is inserted into the first holding section 30.

[0041] A notch 30b is formed in the side wall 30a of the first holding part 30. The side wall 30a in which the notch 30b is formed is, for example, the front side wall. A part of the notch 30b is formed to extend in the vertical direction. The notch 30b is formed, for example, in a substantially L-shape when viewed from the front. The notch 30b may also be formed in a linear shape extending in the vertical direction when viewed from the front. The first tube 20 is inserted into the notch 30b. That is, the first tube 20 is extended forward from the first holding part 30 by the notch 30b.

[0042] The second holding portions 31, 32 hold the connector 4. The second holding portions 31, 32 are formed to protrude forward from the side wall portion 10c of the first holding portion 30. The second holding portions 31, 32 are provided above the ejection portion 11. The second holding portions 31, 32 hold the connector 4 above the ejection portion 11. The second holding portions 31, 32 are provided to be spaced apart in the left-right direction. The second holding portion 31 has openings at its upper and left ends. The second holding portion 32 has openings at its upper and right ends. A portion of the connector 4 is inserted into the second holding portions 31, 32. For example, the second holding portions 31, 32 are formed so that the connection surface 4a (upper end surface) of the connector 4 that connects with the external connector 40 is horizontal.

[0043] In bag 1, after the storage chamber 10a is filled with liquid via filling section 12, seal section 15 is formed. Then, the main body 2 filled with liquid and the discharge tube 3 are inserted into and held by first holding section 30. Furthermore, the connector 4 is inserted into and held by second holding sections 31 and 32. In this way, the main body 2 and the connector 4 are held by holder 5.

[0044] The connector 4 is connected to an external connector 40 while being held by the holder 5. For example, a user holds the holder 5 and connects the connector 4 and the external connector 40 together.

[0045] When liquid is supplied to the cartridge for producing iPS cells, negative pressure is created inside the closed tube 41. This causes the liquid to flow from the storage chamber 10a through the discharge section 11, the discharge tube 3, the connector 4, and the external connector 40 into the closed tube 41. That is, the liquid in the storage chamber 10a is sucked and flows into the closed tube 41. Specifically, the liquid that flows from the storage chamber 10a into the discharge tube 3 via the discharge path 11a flows leftward through the discharge tube 3, has its flow direction changed upward by the joint 22, and flows into the closed tube 41 through the connector 4 and the external connector 40. The liquid is then supplied to the cartridge for producing iPS cells.

[0046] When liquid is discharged from storage chamber 10a, the liquid contained in storage chamber 10a flows into discharge path 11a along bottom 10d of storage chamber 10a. That is, when liquid is discharged from storage chamber 10a, the liquid contained in storage chamber 10a is guided to discharge path 11a along bottom 10d of storage chamber 10a.

[0047] When liquid is discharged from storage chamber 10a, the liquid in storage chamber 10a is sucked in, causing the pressure in storage chamber 10a to become lower than atmospheric pressure. As a result, storage section 10 is pressed from the front and rear by atmospheric pressure, reducing the volume of storage chamber 10a. Storage section 10 is formed to protrude in the front and rear directions. Therefore, when storage chamber 10a is pressed from the front and rear by atmospheric pressure, reducing the volume of storage chamber 10a, the storage section 10 is prevented from wrinkling and being prevented from narrowing.

[0048] Furthermore, by accommodating the biasing portion 13 in the storage chamber 10a, when the storage chamber 10 is pressed from the front-to-rear direction by atmospheric pressure, the side wall portion 10c is biased outward by the biasing portion 13. Therefore, when the storage chamber 10a is pressed from the front-to-rear direction by atmospheric pressure and the volume of the storage chamber 10a decreases, the storage chamber 10 is prevented from wrinkling and being prevented from being constricted.

[0049] Furthermore, the discharge portion 11 is formed to protrude in the front-rear direction, so that when the discharge portion 11 is pressed in the front-rear direction by atmospheric pressure, the discharge portion 11 is prevented from wrinkling and being constricted.

[0050] Furthermore, by accommodating the cylindrical member 14 in the discharge passage 11a, the discharge portion 11 is prevented from being constricted when the discharge portion 11 is pressed from the front and rear directions by atmospheric pressure.

[0051] In a bag according to a comparative example in which this embodiment is not used, for example, the discharge pipe is provided to extend downward from the storage section. Therefore, in the bag according to the comparative example, after the discharge pipe extends downward, for example, the discharge pipe is bent and routed upward. Therefore, in the bag according to the comparative example, the discharge pipe extends downward, and a dead volume is generated on the lower side.

[0052] The bag 1 according to the embodiment includes a storage section 10, a discharge section 11, and a discharge tube 3. The storage section 10 has a storage chamber 10a that stores a liquid such as a sample or a reagent. The discharge section 11 has a discharge path 11a for discharging the liquid from the storage chamber 10a. The discharge tube 3 is connected to the discharge section 11 and discharges the liquid from the storage chamber 10a via the discharge path 11a. The discharge tube 3 is connected to the discharge section 11 so as to extend from the discharge section 11 in a direction having a horizontal component.

[0053] This allows the bag 1 to prevent the discharge pipe 3 from sagging downward, and to prevent the occurrence of dead volume below the storage section 10. For example, when multiple bags 1 are used side by side, the bag 1 can prevent the occurrence of dead volume below the multiple bags 1 that are lined up.

[0054] Furthermore, the discharge unit 11 is provided below the storage unit 10. The discharge path 11a is connected to the lower end of the storage chamber 10a. The bottom 10d of the storage chamber 10a is inclined toward the discharge path 11a. That is, the bottom 10d of the storage chamber 10a is inclined downward, and when liquid is discharged from the storage chamber 10a, the liquid is guided along the bottom 10d of the storage chamber 10a to the discharge path 11a.

[0055] As a result, when liquid is discharged from storage chamber 10a, the liquid flows along bottom 10d of storage chamber 10a and into discharge channel 11a, which communicates with the lower end of storage chamber 10a. Therefore, when discharging liquid from storage chamber 10a, bag 1 can easily discharge the liquid from storage chamber 10a into discharge channel 11a. Furthermore, when discharging liquid from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to a cartridge for producing iPS cells. In other words, bag 1 can supply a specified amount of liquid to a cartridge for producing iPS cells.

[0056] The storage section 10 is formed by joining a portion of the first sheet 100 and a portion of the second sheet 101. The storage section 10 has a peripheral wall portion 10b that rises from a peripheral edge portion 2a, which is the joining portion between the first sheet 100 and the second sheet 101.

[0057] As a result, when the liquid contained in storage chamber 10a is sucked and discharged from storage chamber 10a, bag 1 can prevent wrinkles from occurring in storage section 10 by peripheral wall 10b, and can prevent storage section 10 from becoming constricted. Therefore, when discharging liquid from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to a cartridge for producing iPS cells.

[0058] The container further includes a biasing portion 13 accommodated in the container chamber 10a. The biasing portion 13 biases the side wall portion 10c of the container 10 outward when liquid is discharged from the container chamber 10a.

[0059] As a result, when the liquid contained in storage chamber 10a is sucked and discharged from storage chamber 10a, bag 1 can prevent wrinkles from occurring in storage chamber 10 by using biasing unit 13 to bias side wall 10c outward, thereby preventing storage chamber 10 from becoming constricted. Therefore, when discharging liquid from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to a cartridge for producing iPS cells.

[0060] The discharge portion 11 is formed by joining a portion of the first sheet 100 and a portion of the second sheet 101. The discharge portion 11 includes a peripheral wall portion 11b rising from a peripheral edge portion 2a, which is the joining portion between the first sheet 100 and the second sheet 101.

[0061] As a result, when the liquid contained in storage chamber 10a is sucked and discharged from discharge channel 11a, bag 1 can prevent discharge channel 11a from being crushed by peripheral wall 11b and can prevent discharge channel 11a from being narrowed. Therefore, when discharging liquid from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to a cartridge for producing iPS cells.

[0062] The bag 1 also includes a tubular member 14 housed in the discharge passage 11a.

[0063] As a result, when the liquid contained in storage chamber 10a is sucked and discharged from discharge channel 11a, bag 1 can prevent discharge channel 11a from being constricted by tubular member 14. Therefore, when discharging liquid from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to a cartridge for producing iPS cells.

[0064] Furthermore, the discharge section 11 is formed integrally with the storage section 10.

[0065] This allows bag 1 to have a part of main body 2 function as discharge path 11a. Therefore, bag 1 can connect discharge pipe 3 to main body 2 so that discharge pipe 3 extends in a direction that includes a horizontal component from discharge portion 11, which is formed integrally with storage portion 10. In other words, bag 1 can connect discharge pipe 3 to main body 2 without having discharge pipe 3 extend downward. Therefore, bag 1 can reduce dead volume below storage portion 10.

[0066] The bag 1 also includes a connector 4 and a holder 5. The connector 4 connects the discharge tube 3 to an external connector 40, and allows the liquid to flow from the discharge tube 3 to the external connector 40. The holder 5 holds the storage portion 10, the discharge portion 11, and the connector 4.

[0067] As a result, the user can connect the connector 4 to the external connector 40 while the storage portion 10, the discharge portion 11, and the connector 4 are held by the holder 5. Therefore, the bag 1 can prevent the discharge tube 3 from being pulled or bent when the connector 4 and the external connector 40 are connected. Therefore, the bag 1 can prevent the discharge tube 3 from breaking. Furthermore, the user can connect the external connector 40 to the connector 4 held by the holder 5, for example, while holding the holder 5. Therefore, the user can easily connect the connector 4 and the external connector 40. Furthermore, by holding the storage portion 10 and the discharge portion 11 with the holder 5, the bag 1 can prevent wrinkles from occurring in the storage portion 10 and the discharge portion 11. Furthermore, the holder 5 allows the bag 1 to stand on its own. Therefore, when arranging multiple bags 1, for example, the multiple bags 1 can be arranged stably.

[0068] Moreover, the holder 5 holds the connector 4 above the ejection portion 11 .

[0069] This makes it possible to prevent the discharge pipe 3 from hanging down below the main body 2 when the discharge pipe 3 is connected to the discharge part 11 so as to extend in a direction having a horizontal component from the discharge part 11. Therefore, the bag 1 can reduce the dead volume on the lower side.

[0070] The discharge pipe 3 also includes a first tube 20, a second tube 21, and a joint 22. The first tube 20 is connected to the discharge portion 11. The second tube 21 is connected to the lower surface of the connector 4. The joint 22 connects the first tube 20 and the second tube 21.

[0071] As a result, the bag 1 can arrange the first tube 20 to extend from the discharge portion 11 in a direction having a horizontal component. Furthermore, the bag 1 can arrange the second tube 21 to extend in a vertical direction from the underside of the connector 4. That is, the bag 1 can connect the first tube 20 and the second tube 21 to the joint 22 with minimal bending of the first tube 20 and the second tube 21. Therefore, the bag 1 can prevent the first tube 20 and the second tube 21, which connect the discharge portion 11 and the connector 4, from breaking. Furthermore, the bag 1 can prevent the discharge pipe 3 from sagging below the main body 2. Therefore, the bag 1 can reduce dead volume on the lower side.

[0072] The bag 1 also includes a filling section 12. The filling section 12 has a filling path 12a for filling the storage chamber 10a with a liquid, and is formed to extend downward from the storage chamber 10a.

[0073] This prevents the bag 1 from becoming too long in the front-rear and left-right directions. The filling section 12 is formed to extend downward relative to the storage section 10, which is the same direction as the direction in which the discharge section 11 is provided. Therefore, the bag 1 can effectively utilize the area below the storage section 10. Furthermore, the bag 1 can support the storage section 10 stored in the holder 5 from below by the discharge section 11 and the filling section 12. Therefore, the bag 1 can improve the stability of the main body section 2 inserted into the holder 5.

[0074] The bag 1 also includes a seal portion 15. The seal portion 15 is formed after the storage chamber 10a is filled with liquid, and blocks communication between the filling path 12a and the storage chamber 10a. The filling portion 12a is formed so that the liquid is filled into the storage chamber 10a from the bottom 10d side of the storage chamber 10a. The seal portion 15 is formed to fit along the bottom 10d.

[0075] As a result, when liquid is discharged from storage chamber 10a in bag 1, the liquid flows along seal portion 15 and bottom portion 10d of storage chamber 10a into discharge channel 11a. Therefore, when liquid is discharged from storage chamber 10a in bag 1, the liquid can be easily discharged from storage chamber 10a into discharge channel 11a. Furthermore, when liquid is discharged from storage chamber 10a, bag 1 can prevent liquid from remaining in storage chamber 10a. Therefore, bag 1 can accurately supply the liquid contained in storage chamber 10a to the flow channel on the side of the cartridge for producing iPS cells.

[0076] As shown in Fig. 5, the second holders 31, 32 may be formed so that the connection surface 4a of the connector 4 held by the second holders 31, 32 is inclined relative to the horizontal. Fig. 5 is a front view showing a schematic view of a bag 1 according to a modified example. For example, the second holders 31, 32 are provided so that the connection surface 4a of the connector 4 is inclined toward the base of the tube 41 in a cartridge for producing iPS cells. This allows the user to easily connect the connector 4 to the external connector 40. Furthermore, the bag 1 can reduce the load on the closed tube 41 when the connector 4 is connected to the external connector 40.

[0077] The bag 1 may include either one of the peripheral wall portion 10b and the biasing portion 13. The bag 1 may also include either one of the peripheral wall portion 10b and the tubular member .

[0078] In the above-described embodiment, the separate unit to which bag 1 is connected is a cartridge for producing iPS cells, and the cartridge is installed in an iPS cell production apparatus to produce iPS cells, but the embodiment is not limited to this. For example, the separate unit to which bag 1 is connected may be an iPS cell production apparatus, and iPS cells may be produced without using a cartridge. The above-described embodiment can also be applied to bags that contain samples or reagents used in the production or processing of cells other than iPS cells.

[0079] Although the embodiments have been described, they are presented as examples and are not intended to limit the scope of the invention. The embodiments can be implemented in various other forms, and various omissions, substitutions, and modifications can be made without departing from the spirit of the invention. These embodiments and their modifications are included within the scope and spirit of the invention, as well as within the scope of the invention and its equivalents as set forth in the claims. [Explanation of symbols]

[0080] 1 bag 2 Main body 2a Periphery 3 Discharge pipe 4 Connectors 5 Holder 10 Storage section 10a Containment Cell 10b Peripheral wall part 10c Side wall part 10d bottom 11 Discharge section 11a Exhaust channel 11b Peripheral wall part 12 Filling section 12a Filling path 13. Actuation section 14 Cylindrical member 15 Seal part 20 1st Tube 21 Second Tube 22 joints 30 1st holding part 31 Second holding part 32 Second holding part 40 external connector 100 Sheet 1 101 2nd Sheet

Claims

1. a storage unit having a storage chamber for storing a liquid that is a sample or a reagent; a discharge section having a discharge path for discharging the liquid from the storage chamber; a discharge pipe connected to the discharge portion and configured to discharge the liquid from the storage chamber via the discharge path; Equipped with The discharge pipe is connected to the discharge portion so as to extend from the discharge portion in a direction having a horizontal component.

2. The discharge section is provided below the storage section, The discharge path communicates with a lower end of the storage chamber, The bag of claim 1 , wherein the bottom of the chamber slopes toward the discharge passage.

3. The bottom of the storage chamber is inclined downward, The bag of claim 1 , wherein when the liquid is discharged from the chamber, the liquid is guided along the bottom of the chamber to the discharge path.

4. the storage portion is formed by joining a part of a first sheet and a part of a second sheet, The bag according to claim 1 , wherein the storage section has a peripheral wall section rising from a peripheral edge section that is a joint between the first sheet and the second sheet.

5. a biasing portion accommodated in the accommodation chamber, The bag according to claim 1 , wherein the biasing portion biases the side wall portion of the storage portion outward when the liquid is discharged from the storage chamber.

6. the discharge portion is formed by joining a part of the first sheet and a part of the second sheet, The bag according to claim 1 , wherein the discharge portion has a peripheral wall portion rising from a peripheral edge portion that is a joint between the first sheet and the second sheet.

7. A cylindrical member accommodated in the discharge path The bag of claim 1 , comprising:

8. The bag of claim 1 , wherein the discharge portion is integrally formed with the storage portion.

9. a connector that connects the discharge pipe to an external connector of a separate unit and allows the liquid to flow from the discharge pipe to the external connector; a holder that holds the receiving portion, the discharging portion, and the connector; The bag of claim 1 , comprising:

10. The bag of claim 9 , wherein the holder holds the connector above the discharge portion.

11. The discharge pipe is a first tube connected to the discharge portion; a second tube connected to a lower surface of the connector; a joint connecting the first tube and the second tube; 10. The bag of claim 9, comprising:

12. a filling section that has a filling path for filling the liquid into the storage chamber and is formed so as to extend downward from the storage section; The bag of claim 1 , comprising:

13. a seal portion that is formed after the liquid is filled into the storage chamber and that blocks communication between the filling path and the storage chamber; Equipped with the filling section is formed to fill the liquid into the storage chamber from a bottom side of the storage chamber, The bag of claim 12, wherein the seal is formed to conform to the bottom.

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