Polymer, test agent, analyte concentration measurement method, and analyte concentration measurement device

The polymer with aggregation-induced luminescent groups and functional groups addresses background fluorescence interference, enhancing detection sensitivity by spontaneous binding and entanglement, thus improving analyte measurement.

JP7765173B2Active Publication Date: 2025-11-06SEKISUI CHEMICAL CO LTD
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Patent Information

Application Number
JP2020167158
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Filing Date
2020-10-01
Publication Date
2025-11-06
Estimated Expiration
2040-10-01

AI Technical Summary

Technical Problem

Conventional fluorescence methods suffer from background fluorescence interference, limiting sensitivity and specificity, and existing aggregated luminescent materials require condensing agents that restrict molecular motion, further reducing detection sensitivity.

Method used

A polymer with aggregation-induced luminescent groups and functional groups that spontaneously bind to a binding partner, suppressing background fluorescence and enhancing detection sensitivity by preventing direct binding between luminescent groups and binding partners.

Benefits of technology

The polymer effectively suppresses background fluorescence and achieves higher detection sensitivity by allowing the polymer to entangle and emit fluorescence, improving analyte detection without the need for condensing agents.

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Abstract

To provide a polymer which allows for suppressing background fluorescence and measuring an analyte with good detection sensitivity by introducing a binding partner, and to provide a test agent containing the polymer, an analyte concentration measurement method using the polymer, and an analyte concentration measurement device used to implement the analyte concentration measurement method.SOLUTION: A polymer is provided, having an aggregation-induced light-emitting group and a functional group that spontaneously binds to a binding partner capable of binding to an analyte on a polymer skeleton.SELECTED DRAWING: None
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Citation Information

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