UV polymerizable antimicrobial imidazolidinyl urea-based acrylate resin for 3D printing applications

A polymeric chain of imidazolidinyl urea monomers is used to create a photocurable resin for 3D printing, addressing the limitations of existing resins by providing high-resolution printing with antimicrobial and mechanical enhancements, suitable for biomedical applications.

WO2025191557A1 Publication Date: 2025-09-18TECHNION RES & DEV FOUND LTD
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Patent Information

Application Number
PCT/IL2025/050226
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-03-12
Filing Date
2025-03-10
Publication Date
2025-09-18

AI Technical Summary

Technical Problem

The limited availability of photoactive resins for 3D printing poses challenges in achieving desired material properties, particularly in terms of mechanical properties and antimicrobial capabilities, with existing acrylate-based systems resulting in highly crosslinked, inhomogeneous networks with inferior mechanical properties.

Method used

Development of a polymeric chain comprising imidazolidinyl urea monomers, which can be crosslinked, alkylated, halogenated, or conjugated to drugs, forming a photocurable resin suitable for 3D printing, offering antimicrobial properties and improved mechanical behavior.

Benefits of technology

The developed resin achieves high-resolution 3D printing with excellent antimicrobial properties against bacteria, maintaining cytocompatibility and blood compatibility, and tunable thermal and mechanical properties, making it suitable for biomedical applications.

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Abstract

The present invention provides a polymeric chain made of acrylate-containing imidazolidinyl urea monomers and having antimicrobial properties, a UV polymerizable resin comprising said polymeric chain, and a product such as a medical device, obtained by 3D printing of said UV polymerizable resin.
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