A delivery system containing a transcatheter endoluminal prosthesis

The delivery system addresses the need for minimally invasive treatment of thoracic aortic aneurysms and dissections by using a self-expanding prosthesis with locking mechanisms for precise transcatheter implantation, reducing surgical risks and ensuring secure anchoring and blood flow continuity.

WO2025262094A1 Publication Date: 2025-12-26TT3A SRL
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Patent Information

Application Number
PCT/EP2025/066999
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2024-06-18
Filing Date
2025-06-17
Publication Date
2025-12-26

AI Technical Summary

Technical Problem

Existing treatments for thoracic aortic aneurysms and dissections, particularly in the ascending aorta, involve high-risk open heart surgery, and there is a need for a minimally invasive, safe, and effective transcatheter delivery system for cardiac prostheses.

Method used

A delivery system comprising an inner tube, metal tube, and outer catheter shaft, with a self-expanding endoluminal prosthesis featuring distal and proximal locking mechanisms, allowing controlled deployment and anchoring of a stent-valve and stent-graft parts in the ascending aorta and aortic valve, facilitated by guide wires and rotating paddles for precise alignment and implantation.

Benefits of technology

Enables safe and precise implantation of aortic prostheses on a beating heart, reducing morbidity and mortality risks associated with open heart surgery, while providing secure anchoring and blood flow continuity.

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Abstract

The subject of the invention is a delivery system for delivering a self-expanding endoluminal prosthesis to the patient's ascending aorta and aortic valve, the system comprising: - an inner tube (33), extending along a longitudinal Y axis of the delivery system (100), from an atraumatic distal tip (27) to a handle (37); - a metal tube (32), slide-fitted on the inner tube (33), and extending from the internal space of the distal tip (27) to a handle (37); - an outer tubular catheter shaft (22) slide-fitted on the metal tube (32), the catheter shaft (22) is brought out from the handle (37) and is terminated by a capsule (20), containing inside the radially compressed on the metal tube (32), self-expanding endoluminal prosthesis (1) having defined construction and covered at least partially by a coating (16), - the capsule (20) has closed position when is closed by the tip (27) and has open position when the capsule (20) and the tip (27) are displaced relative to each other; wherein the distal part of the metal tube (32) is equipped with receiving means (41, 42) on which the distal locking means (7) of prosthesis (1) are removably embedded and blocked in the inner space of the tip (27) and the delivery system (100) comprises also removable holding means (45, 45') retaining the proximal locking means (9) of the prosthesis (1), so that when the capsule (20) is in its fully open position, the prosthesis (1) is still maintained partially compressed, holding its crimping length.
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