A cell concentration system and method

A technology for concentrating system and cells, applied in the field of medical biological assay, can solve the problems of uncontrollable overlapping and loss of cells, uneven distribution of cells, etc., to reduce the overlapping of cells, prevent clogging, and improve quality.

CN108414341BActive Publication Date: 2021-12-28MACCURA MEDICAL INSTR CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Publication Date
2021-12-28

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Abstract

The invention discloses a cell concentration system and method, comprising: a sample bottle, including a bottle body and a bottle cap matched with the bottle body, a filter device is arranged in the bottle body, and a first cavity is formed by the bottle body, the bottle cap and the filter device Body, the bottle bottom of the bottle body and the filtering device form a second cavity; the loading mechanism can transfer the sample bottle; the concentration and mixing mechanism can pierce the bottom of the bottle, and perform suction and reverse blowing operations on the sample bottle; And the controller, after the controller controls the loading mechanism to transfer the sample bottle to the concentration position, the controller controls the concentration and mixing mechanism to pierce the bottom of the bottle and enter the second cavity, and repeatedly perform the suction operation and reverse air blowing operation. Since the cell concentration system of the present invention is used to carry out cell concentration by performing suction operation and reverse blowing operation, it can effectively prevent the filter device and concentration needle from clogging the sample bottle, and can effectively reduce the concentration of cells while accelerating cell concentration. Cells are superimposed, thereby improving the quality of cell enrichment.
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Description

technical field

[0001] The invention relates to the technical field of medical bioassays, and more specifically relates to a cell concentration system and method. Background technique

[0002] In medical testing, it is often necessary to enrich a specific cell in the specimen, and then identify the cells. In order to ensure the accuracy of the test and the number of cells required for the test, it is usually necessary Enrichment is carried out under certain conditions, which can prevent infection and pollution, and ensure the safety of operators and the surrounding environment.

[0003] At present, liquid-based products on the market adopt two methods for cell enrichment: one is to enrich cells by centrifugation after shaking and mixing. The operation process is as follows: manually shake the sample in the vortex shaker, and then manually place the mixed sample on the sample transfer machine to transfer the sample to the centrifuge tube, and then put the centrifuge tube int...

Examples

Embodiment Construction

[0063] The core of the present invention is to provide a cell concentration system and a cell concentration method to improve the quality of cell concentration.

[0064] In addition, the examples shown below do not limit the content of the invention described in the claims in any way. In addition, all the contents of the configurations shown in the following embodiments are not limited to be essential to the solution of the invention described in the claims.

[0065] see Figure 1 to Figure 8 , the cell concentration system of the embodiment of the present invention, comprising:

[0066] The sample bottle 100 includes a bottle body 101 and a bottle cap 102 matched with the bottle body 101. A filter device 104 is arranged in the bottle body 101. The bottle body 101, the bottle cap 102 and the filter device 104 form a first cavity 105. The bottle body The bottom 103 of the bottle 101 and the filter device 104 form a second cavity 106;

[0067] a loading mechanism 200 capable ...