Automatic positioning seeder

By introducing automatic positioning and sterile sealing technology into cell culture seeders, the problems of insufficient intelligence and lax sealing of seeders are solved, and efficient and accurate cell seeding and sterile operation are achieved.

CN108504565BActive Publication Date: 2025-08-22XINSHENGYUANCHUANG (XIAMEN) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN201710107548.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2017-02-27
Publication Date
2025-08-22
Estimated Expiration
2037-02-27

AI Technical Summary

Technical Problem

The existing cell culture seeders are not mechanically intelligent enough, and they are prone to deviations during the sowing process, have low seeding rate, and are easily disturbed by bacteria during sealing.

Method used

An automatic positioning seed machine is designed, using transmission guide rails, touch control panels, robots, infrared sensing probes, thermal sealing devices and other components to achieve accurate seeding and sterile sealing. The operation convenience is improved through the PCL touch screen control panel. The robots are movably connected to the linear guide rails, and the thermal sealing device uses a sterile thermal sealing film.

Benefits of technology

Improves the accuracy and rate of seeding, ensures sealing in a sterile environment, and reduces the risk of bacterial interference.

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Abstract

The present invention discloses an automatic positioning seeder, comprising a transmission guide rail, a touch control panel, a cell placement tray, a chassis, a seeding device, a heat sealing device, a positioning block, a positioning switch, a gripping device, a linear track, an infrared sensor probe, a manipulator, an inoculation tray, a sterile heat sealing film, a pneumatic lifting cylinder, a waste film roller, a guide roller, a heating strip and a motion stepping motor. The beneficial effect of the present invention is that the control of the device is more convenient and quick by installing a PCL touch screen control panel inside the device. By installing a positioning block on one side of the seeding device of the device and cooperating with a gripping device installed on one side of the seeding device, the gripping device is connected to a linear guide rail on which an infrared sensor probe is installed, so that the seeding accuracy of the device is higher and the speed is faster. By installing a heat sealing device on one side of the gripping device, the device can directly seal the culture after seeding. The device has the characteristics of a high degree of mechanical intelligence and high seeding efficiency.
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Description

Technical Field

[0001] The invention relates to a seeder, in particular to an automatic positioning seeder, belonging to the technical field of cell culture. Background Art

[0002] Cell culture, also known as cell cloning technology, is formally known in biology as cell culture technology. Whether it's bioengineering technology as a whole or biological cloning technology as a specific area, cell culture is an essential process. Cell culture itself is the large-scale cloning of cells. Cell culture technology allows a single cell to be cultured in large quantities to become a simple single cell or minimally differentiated multicellular cells. Cell culture can produce large numbers of cells or their metabolites. Because biological products are all derived from cells, cell culture technology can be said to be the core and most fundamental technology in biotechnology. The large-scale cell culture process requires the use of a series of equipment, including a seeding machine for seeding the inoculation tray.

[0003] However, existing seeders for cell culture still have certain drawbacks. They are not intelligent enough, leading to deviations during seeding, low seeding rates, and the possibility of bacterial interference during the sealing process after seeding. Therefore, an automatic positioning seeder is proposed to address these issues. Summary of the Invention

[0004] The purpose of the present invention is to provide an automatic positioning seeder in order to solve the above problems.

[0005] The present invention achieves the above-mentioned purpose through the following technical scheme: an automatic positioning seeder, comprising a transmission guide rail, a touch control panel installed on one side of the transmission guide rail, a cell placement plate installed on one side of the touch control panel, and a chassis provided on the other side of the touch control panel, a plurality of seeding devices installed on the chassis, positioning blocks installed on both sides of the seeding devices, a positioning switch provided at one end of the positioning block, a grasping device installed on one side of the seeding device, a manipulator installed inside the grasping device, the manipulator installed on a linear guide rail, a heat sealing device installed on one side of the seeding device, a pneumatic lifting cylinder installed above the heat sealing device, and a heating strip provided below the pneumatic lifting cylinder, a guide roller installed on one side of the pneumatic lifting cylinder, and an inoculation plate provided below the heat sealing device.

[0006] Preferably, in order to make the gripping efficiency of the manipulator higher and more stable, the manipulator has a three-claw structure, and the manipulator is movably connected to the linear guide rail.

[0007] Preferably, a plurality of infrared sensor probes with uniform spacing are installed on the linear guide rail.

[0008] Preferably, in order to prevent the heat sealing device from causing bacterial interference during sealing and to automatically remove discarded films, a sterile heat sealing film is installed on one side of the heat sealing device, and a discarded film roller is installed on the other side of the heat sealing device.

[0009] Preferably, in order to provide a stable operating environment for the device during operation, motion stepping motors are installed on both sides of the heat sealing device.

[0010] Preferably, in order to ensure that there is sufficient power source when the device is running, the sowing device, the grasping device and the heat sealing device are all electrically connected to the touch screen control panel.

[0011] Preferably, in order to make the operation of the sowing device follow a specific trajectory and thus reduce the probability of error, the sowing device is movably connected to the transmission guide rail.

[0012] Preferably, in order to enable the device to be directly packaged after sowing, thereby improving processing efficiency, the gripping device and the heat sealing device are both located on one side below the sowing device.

[0013] The present invention has the following beneficial effects: A PCL touchscreen control panel installed within the device makes control of the device more convenient and quick. By installing a positioning block on one side of the device's seeding mechanism, combined with a gripping device installed on the side of the device, and connecting the gripping device to a linear guide rail equipped with an infrared sensor probe, the device achieves higher seeding accuracy and faster seeding rates. A heat sealing device installed on the side of the gripping device allows the device to directly seal the culture after seeding. A sterile heat sealing film is installed on the heat sealing device, allowing the seeded culture to grow and develop in a sterile environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0015] Figure 2 It is a structural schematic diagram of the sowing device of the present invention.

[0016] Figure 3 It is a schematic structural diagram of the grabbing device of the present invention.

[0017] Figure 4 It is a schematic structural diagram of the heat sealing device of the present invention.

[0018] In the figure: 1. Transport guide rail, 2. Touch control panel, 3. Cell placement tray, 4. Chassis, 5. Seeding device, 6. Heat sealing device, 7. Positioning block, 8. Positioning switch, 9. Grabbing device, 10. Linear track, 11. Infrared sensor probe, 12. Robot, 13. Inoculation tray, 14. Sterile heat sealing film, 15. Pneumatic lifting cylinder, 16. Waste film roller, 17. Guide roller, 18. Heating strip, 19. Motion stepper motor. DETAILED DESCRIPTION

[0019] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] See also Figure 1-4 As shown, an automatic positioning seeder includes a transmission guide rail 1, a touch control panel 2 is installed on one side of the transmission guide rail 1, a cell placement plate 3 is installed on one side of the touch control panel 2, and a chassis 4 is provided on the other side of the touch control panel 2, a plurality of seeding devices 5 are installed on the chassis 4, positioning blocks 7 are installed on both sides of the seeding devices 5, a positioning switch 8 is provided at one end of the positioning block 7, a grasping device 9 is installed on one side of the seeding device 5, a manipulator 12 is installed inside the grasping device, and the manipulator 12 is installed on a linear guide rail 10, a heat sealing device 6 is installed on one side of the seeding device 5, a pneumatic lifting cylinder 15 is installed above the heat sealing device 6, and a heating strip 18 is provided below the pneumatic lifting cylinder 15, a guide roller 17 is installed on one side of the pneumatic lifting cylinder 15, and an inoculation plate 13 is installed below the heat sealing device 6.

[0021] As a technical optimization solution of the present invention, the manipulator 12 has a three-claw structure, and the manipulator 12 is movably connected to the linear guide rail 10 .

[0022] As a technical optimization solution of the present invention, a plurality of infrared sensor probes 11 with uniform spacing are installed on the linear guide rail 10.

[0023] As a technical optimization solution of the present invention, a sterile heat-sealing film 14 is installed on one side of the heat-sealing device 6, and a waste film roller 16 is installed on the other side of the heat-sealing device 6.

[0024] As a technical optimization solution of the present invention, motion stepping motors 19 are installed on both sides of the heat sealing device 6.

[0025] As a technical optimization solution of the present invention, the sowing device 5 , the gripping device 9 , and the heat sealing device 6 are all electrically connected to the touch screen control panel 2 .

[0026] As a technical optimization solution of the present invention, the sowing device 5 is movably connected to the transmission guide rail 1.

[0027] As a technical optimization solution of the present invention, the grabbing device 9 and the heat sealing device 6 are both located on one side below the sowing device 5.

[0028] When the present invention is in use, first, the device is fixed and installed, and secondly, the device is started by touching the control panel 2. The seeding device 5 grabs the cultured cells stored in the cell placement tray 3 through the grabbing device 9 and inoculates them onto the inoculation tray 13 on the chassis 4 through the manipulator 12. During the inoculation process, the seeding device 5 monitors the moving distance of the seeding device in real time through the positioning blocks 7 on both sides and the infrared sensor probe 11 on the linear guide 10 inside the grabbing device 9 to ensure the accuracy of the inoculation. Finally, after the inoculation is completed, the inoculation tray 13 is sealed by the heat sealing device 6. During the sealing process, the sterility of the seal is ensured and there will be no unsealed situation through the combined action of the sterile heat sealing film 14 and the waste film roller 16.

[0029] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the invention can be embodied in other specific forms without departing from the spirit or essential characteristics of the invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be included therein. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0030] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. An automatic positioning seed drill, comprising a transmission guide rail (1), characterized in that: A touch control panel (2) is installed on one side of the transmission guide rail (1), a cell placement plate (3) is installed on one side of the touch control panel (2), and a chassis (4) is installed on the other side of the touch control panel (2). A plurality of seeding devices (5) are installed on the chassis (4), positioning blocks (7) are installed on both sides of the seeding devices (5), and a positioning switch (8) is provided at one end of the positioning block (7). A gripping device (9) is installed on one side of the seeding device (5), a manipulator (12) is installed inside the gripping device, and the manipulator (12) is installed on the linear guide rail (10). A heat sealing device (6) is installed on one side of the device (5), a pneumatic lifting cylinder (15) is installed above the heat sealing device (6), and a heating strip (18) is provided below the pneumatic lifting cylinder (15), a guide roller (17) is installed on one side of the pneumatic lifting cylinder (15), and an inoculation plate (13) is installed below the heat sealing device (6); wherein, a sterile heat sealing film (14) is installed on one side of the heat sealing device (6), and a waste film roller (16) is installed on the other side of the heat sealing device (6); wherein, the grabbing device (9) and the heat sealing device (6) are both located on one side below the sowing device (5).

2. The automatic positioning seeder according to claim 1, characterized in that: The manipulator (12) has a three-claw structure, and the manipulator (12) is movably connected to the linear guide rail (10).

3. The automatic positioning seeder according to claim 1, characterized in that: A plurality of infrared sensor probes (11) with uniform spacing are installed on the linear guide rail (10).

4. The automatic positioning seeder according to claim 1, characterized in that: Motion stepping motors (19) are installed on both sides of the heat sealing device (6).

5. The automatic positioning seeder according to claim 1, characterized in that: The sowing device (5), the grabbing device (9), and the heat sealing device (6) are all electrically connected to the touch control panel (2).

6. The automatic positioning seeder according to claim 1, characterized in that: The sowing device (5) is movably connected to the transmission guide rail (1).

Citation Information

Patent Citations

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