A membrane oxygenator with an integrated centrifugal pump and variable temperature.

Abstract

The present invention discloses a membrane oxygenator with an integrated centrifugal pump with variable temperature, comprising a centrifugal pump system, a variable temperature system and a gas exchange device; the centrifugal pump system is fixedly installed below the gas exchange device; the variable temperature system is inside the gas exchange device; the membrane oxygenator also comprises a blood inlet nozzle, a bleeding nozzle, an air inlet nozzle, an exhaust nozzle, a water inlet nozzle and a bleeding nozzle. The membrane oxygenator provided by the present invention is small in size, easy to transport, suitable for emergency environments; easy to use and operate, and reduces operating errors.

Description

Technical Field

[0001] The invention relates to the technical field of medical device products, in particular to designing a membrane oxygenator with a temperature-variable integrated centrifugal pump. Background Art

[0002] Hollow fiber membrane oxygenator (hereinafter referred to as oxygenator) is the gold standard of blood Yanghe today. In the long-term use process, the oxygenator has gradually been applied to more medical fields, such as respiratory support, first aid, neonatal and even battlefield first aid, from a device supporting cardiac surgery at the beginning.

[0003] Since traditional oxygenators are products developed for cardiac surgery, they are only considered for short-term use in the operating room. Therefore, there are still many problems in the expansion of the use of oxygenators on the market, especially in emergency, hospital transfer, intra-hospital transfer, etc., which require life support on the move. There are still many shortcomings, such as large size of the equipment, large amount of pipeline preparation, slow and cumbersome connection, and inconvenient to move, which greatly limits the clinical use of oxygenators.

[0004] With the increasing clinical needs, how to make the traditional extracorporeal circulation operation simpler and faster, and how to make the equipment smaller and more flexible, so that the extracorporeal circulation can be better used in emergency treatment and transportation has become one of the goals of the development of extracorporeal circulation technology. The existing membrane oxygenator volume is mostly 0.4*0.4*1.5 cubic meters; the operation steps are cumbersome, there are many leakage points, and at least 1 meter of connecting pipes are required, which increases the risk of blood damage. Summary of the invention

[0005] In order to solve the above problems, the present invention provides a membrane oxygenator with an integrated centrifugal pump with variable temperature, comprising a centrifugal pump system, a variable temperature system and a gas exchange device; the centrifugal pump system is fixedly installed below the gas exchange device; the variable temperature system is inside the gas exchange device; the membrane oxygenator also includes a blood inlet nozzle, a bleeding nozzle, an air inlet nozzle, an exhaust nozzle, a water inlet nozzle and a bleeding nozzle.

[0006] Furthermore, the centrifugal pump system includes a blood inlet housing, a bleeding housing, an impeller and a lower housing; the impeller is installed outside the blood inlet housing, and the bleeding housing is installed inside the blood inlet housing; the lower housing is fixedly installed below the blood inlet housing and the bleeding housing.

[0007] Furthermore, the gas exchange device includes an upper cover, a lower cover, an outer shell, a first blocking layer, a second blocking layer, a blood inlet core shaft, an outer core shaft, a temperature-changing shell, a temperature-changing membrane and an oxygen pressure membrane; the upper cover and the lower cover are both provided with a water inlet spacer; the blood inlet core shaft is located in the middle of the outer shell; the outer core shaft is located outside the blood inlet core shaft; the temperature-changing membrane is installed on the outside of the outer core shaft; the temperature-changing shell is located outside the temperature-changing membrane; the oxygen pressure membrane is located outside the temperature-changing shell and inside the outer shell; the upper cover and the lower cover are installed on the top and bottom of the outer shell, The water inlet spacers in the upper cover and the lower cover are connected and fixed to the temperature-changing chamber shell; a blood channel is provided in the middle of the upper cover; the blood channel is fixedly connected to the blood inlet core shaft by mortise and tenon joints, and mainly plays a sealing and fixing role; the first blocking layer is installed on the upper part of the cavity between the blood inlet core shaft and the outer core shaft, the top of the temperature-changing membrane and the top of the oxygen pressure membrane; the second blocking layer is installed on the bottom of the temperature-changing membrane, the bottom of the oxygen pressure membrane and the lower part of the cavity between the oxygen pressure membrane and the outer shell; one or more bleeding holes are provided on the outer core shaft and the temperature-changing chamber shell.

[0008] Furthermore, the centrifugal pump system is installed at the bottom of the gas exchange device; the blood inlet shell is fixed on the blood inlet core shaft; the blood outflow shell is fixed in the middle of the lower cover, and its top is fixedly connected to the outer core shaft; the centrifugal pump system and the gas exchange device are coaxially connected and installed.

[0009] Furthermore, a first blood channel is formed between the blood inlet housing and the impeller; and a second blood channel is formed between the blood inlet housing and the bleeding housing.

[0010] Furthermore, the blood inlet shell is provided with one or more bleeding holes.

[0011] Furthermore, the interior of the blood inlet core shaft is a first blood channel; a second blood channel is formed between the blood inlet core shaft and the outer core shaft; and a third blood channel is formed between the oxygen pressure membrane and the outer shell.

[0012] Furthermore, the first blocking layer on the first blood channel is located on the top thereof; and the second blocking layer on the third blood channel is located on the bottom thereof.

[0013] Furthermore, the blood inlet nozzle is located on the blood inlet core shaft and is connected to the first blood channel; the bleeding nozzle is located on the outer shell and is connected to the third blood channel; the air inlet nozzle is located on the upper cover, on the outside of the water inlet spacer; the exhaust nozzle is located on the lower cover, on the outside of the water inlet spacer; the water inlet nozzle is located on the lower cover, on the inside of the water inlet spacer; the bleeding nozzle is located on the upper cover, on the inside of the water inlet spacer.

[0014] Furthermore, the blood inlet core shaft, the outer core shaft, the temperature-changing chamber shell, the outer shell, the lower cover, the upper cover, the impeller, the blood inlet shell and the blood discharge shell are all coaxially installed.

[0015] The present invention provides a membrane oxygenator with an integrated centrifugal pump, which has the following technical effects:

[0016] (1) The centrifugal pump system is integrated in the gas exchange device, which has a high degree of integration, reduces the volume of the entire system, is easy to carry, and is more convenient for use in mobile life support such as emergency treatment and transportation.

[0017] (2) The centrifugal pump and the gas exchange device are integrated into one, and there is no need to connect the two through an external hose, which reduces the number of installation steps during first aid and saves rescue time. The use of hoses is reduced, thereby reducing the pre-charge volume, thereby reducing the risk of blood damage and hose detachment.

[0018] (3) A centrifugal pump system is used instead of an extrusion system to reduce the risk of particles falling off during the extrusion process, thereby preventing particles from entering the human body and improving safety performance.

[0019] (4) The volume of this product is 0.4*0.4*0.4 cubic meters, and the weight (including equipment) is less than 50kg, which is easy to carry and transport, reducing the floor space occupied by medical supplies.

[0020] (5) Only two intubations are required during the installation operation, which reduces the risk of manual operation errors and reduces transportation costs.

[0021] (6) It is equipped with a temperature-variable membrane, through which hot water can be introduced to change the temperature of the blood, thereby meeting the requirements of raising or lowering the blood temperature, and further controlling the blood temperature according to the needs of the operation.

[0022] (7) The centrifugal pump and temperature-changing system are integrated at the same time. The product in a sterile package can realize the three functions of temperature change, gas exchange, and centrifugal pump. This allows more medical products to be loaded / prepared in the same space in an ambulance or on the battlefield, saving transportation space. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a side sectional structural diagram of the membrane oxygenator provided by the present invention from a first viewing angle.

[0024] Figure 2 It is a side sectional structural diagram of the membrane oxygenator provided by the present invention from a second viewing angle.

[0025] Figure 3 It is a stereoscopic diagram of the membrane oxygenator provided by the present invention.

[0026] Figure 4The figure is a schematic diagram of the blood flow path of the membrane oxygenator provided by the present invention.

[0027] Figure 5 Schematic diagram of the flow routes of gas and water in the membrane oxygenator provided by the present invention (in the figure, the dark black arrow is the flow route of water; the light black arrow is the flow route of gas).

[0028] Figure 6 It is a schematic diagram of the mortise and tenon structure of the membrane oxygenator provided by the present invention. DETAILED DESCRIPTION

[0029] Embodiment 1

[0030] like Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 As shown, the present invention provides a membrane oxygenator with an integrated centrifugal pump with variable temperature, comprising a centrifugal pump system, a variable temperature system and a gas exchange device; the centrifugal pump system is fixedly installed below the gas exchange device; the variable temperature system is inside the gas exchange device; the membrane oxygenator also includes a blood inlet nozzle 4, a blood nozzle 5, an air inlet nozzle 6, an exhaust nozzle 7, a water inlet nozzle 8 and a blood nozzle 9.

[0031] Specifically, the centrifugal pump system includes a blood inlet shell 11, a bleeding shell 12, an impeller 13 and a lower shell 14; the impeller 13 is installed inside the blood inlet shell 11, and the bleeding shell 12 is installed outside the blood inlet shell 11; the lower shell 14 is fixedly installed below the blood inlet shell 11 and the bleeding shell 12.

[0032] Specifically, the gas exchange device includes an upper cover 21, a lower cover 22, an outer shell 23, a first blocking layer 24, a second blocking layer 25, a blood inlet mandrel 26, an outer mandrel 27, a temperature-changing housing 31, a temperature-changing membrane 32 and an oxygen pressure membrane 28; a water inlet spacer 33 is provided on both the upper cover 21 and the lower cover 22; the blood inlet mandrel 26 is located in the middle of the outer shell 23; the outer mandrel 27 is located outside the blood inlet mandrel 26; the temperature-changing membrane 32 is installed outside the outer mandrel 27; the temperature-changing housing 31 is located outside the temperature-changing membrane 32; the oxygen pressure membrane 28 is located outside the temperature-changing housing 31 and inside the outer shell 23; the upper cover 21 and the lower cover 22 are installed on the outer shell 2 3, the water inlet spacer 33 in the upper cover 21 and the lower cover 22 is connected and fixed to the temperature-changing housing 31; a blood channel is provided in the middle of the upper cover 21; the blood channel is fixedly connected to the blood inlet core shaft 26 by mortise and tenon joints, which plays a sealing and fixing role; the first blocking layer 24 is installed at the upper part of the cavity between the blood inlet core shaft 26 and the outer core shaft 27, the top of the temperature-changing membrane 32 and the top of the oxygen pressure membrane 28; the second blocking layer 25 is installed at the bottom of the temperature-changing membrane 32, the bottom of the oxygen pressure membrane 28 and the lower part of the cavity between the oxygen pressure membrane 28 and the outer shell 24; one or more bleeding holes are provided on the outer core shaft 27 and the temperature-changing housing 31.

[0033] Specifically, the centrifugal pump system is installed at the bottom of the gas exchange device; the blood inlet shell 11 is fixed on the blood inlet core shaft 26; the blood outflow shell 12 is fixed in the middle of the lower cover 22, and its top is fixedly connected to the outer core shaft 27; the centrifugal pump system and the gas exchange device are coaxially connected and installed.

[0034] Specifically, a first blood channel 34 is formed between the blood inlet housing 11 and the impeller 13 ; and a second blood channel 35 is formed between the blood inlet housing 11 and the bleeding housing 12 .

[0035] Specifically, the blood inlet housing 11 is provided with one or more bleeding holes.

[0036] Specifically, the interior of the blood inlet core shaft 26 is a first blood channel 34 ; a second blood channel 35 is formed between the blood inlet core shaft 26 and the outer core shaft 27 ; and a third blood channel 36 is formed between the oxygen pressure membrane 28 and the outer shell 24 .

[0037] Specifically, the first blocking layer 24 on the first blood channel 34 is located on the top thereof; and the second blocking layer 25 on the third blood channel 36 is located on the bottom thereof.

[0038] Specifically, the blood inlet nozzle 4 is located on the blood inlet core shaft 26, and is connected to the first blood channel 34; the bleeding nozzle 5 is located on the outer shell 23, and is connected to the third blood channel 36; the air inlet nozzle 6 is located on the upper cover 21, on the outside of the water inlet spacer 33; the exhaust nozzle 7 is located on the lower cover 22, on the outside of the water inlet spacer 33; the water inlet nozzle 8 is located on the lower cover 22, on the inside of the water inlet spacer 33; the bleeding nozzle 9 is located on the upper cover 21, on the inside of the water inlet spacer 33.

[0039] Specifically, the blood inlet mandrel 26, the outer mandrel 27, the temperature-changing housing 31, the outer housing 23, the lower cover 22, the upper cover 21, the impeller 13, the blood inlet housing 11 and the blood bleeding housing 12 are all coaxially mounted.

[0040] Working principle: Before use, the blood inlet nozzle 4, the bleeding nozzle 5, the air inlet nozzle 6, the exhaust nozzle 7, the water inlet nozzle 8 and the water outlet nozzle 9 are respectively connected to other devices through a catheter, and then they start to work. The blood enters the first blood channel 34 inside the blood inlet core shaft 26 from the blood inlet nozzle 4, flows downward along the first blood channel 34, and enters the first blood channel 34 between the blood inlet shell 11 and the impeller 13 in the centrifugal pump system. Under the action of the centrifugal force of the impeller 13, the blood flows out from one or more bleeding holes on the blood inlet shell 11 and enters the second blood channel 35 between the blood inlet shell 11 and the bleeding shell 12. And under the action of the centrifugal force, the blood enters the second blood channel 35 between the blood inlet core shaft 26 and the outer core shaft 27 along the second blood channel 35. Because the first blocking layer 24 is provided on the top of the second blood channel 35 between the blood inlet core shaft 26 and the outer core shaft 27, the blood enters the temperature-changing membrane 32 from the outer core shaft 27, and the temperature is changed in the temperature-changing membrane 32. Then, the blood enters the oxygen pressure membrane 28 from the temperature-changing housing 31, and gas exchange is performed in the oxygen pressure membrane 28. Finally, the blood enters the third blood channel 36 between the oxygen pressure membrane 28 and the housing 23, and finally flows out from the bleeding nozzle 5 and enters the human body.

[0041] like Figure 5 In the direction indicated by the dark black arrow, water flows in from the water inlet 8 on the lower cover 22, flows in from the bottom of the temperature-changing membrane 32, flows upward under the action of water pressure, flows out from the top of the temperature-changing membrane 32, and finally flows out from the water outlet 9 on the upper cover 21. In the temperature-changing membrane 32, blood and water achieve heat exchange. Because the flow direction of water is perpendicular to the flow direction of blood, more efficient energy exchange can be achieved.

[0042] like Figure 5In the direction indicated by the light black arrow, the gas enters from the air inlet nozzle 6 on the upper cover 21, passes through the first blocking layer 24, and enters the oxygen pressure membrane 28. After achieving gas exchange with the blood in the oxygen pressure membrane 28, the gas passes through the second blocking layer 25, and is finally discharged from the exhaust nozzle 7 on the lower cover 22.

[0043] like Figure 6 As shown, the blood inlet mandrel 26 and the blood inlet shell 11 are fixedly connected by mortise and tenon joints; the top of the blood inlet mandrel 26 is a tenon, and the top of the blood inlet shell 11 is a mortise. The tenon at the bottom of the blood inlet mandrel 26 is inserted into the mortise at the top of the blood inlet shell 11 to connect and fix the two. The mortise and tenon joint connection can fix the two and also play a sealing role to prevent blood leakage. Other mortise and tenon structures in the present invention are the same as this mortise and tenon structure.

[0044] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

Claims

1. A membrane oxygenator with an integrated centrifugal pump with variable temperature, characterized in that: It includes a centrifugal pump system, a temperature-changing system and a gas exchange device; the centrifugal pump system is fixedly installed below the gas exchange device; the temperature-changing system is inside the gas exchange device; the membrane oxygenator also includes a blood inlet nozzle, a blood nozzle, an air inlet nozzle, an exhaust nozzle, a water inlet nozzle and a water outlet nozzle; the gas exchange device includes an upper cover, a lower cover, an outer shell, a first blocking layer, a second blocking layer, a blood inlet mandrel, an outer mandrel, a temperature-changing temperature shell, a temperature-changing membrane and an oxygen pressure membrane; a water inlet spacer is provided on both the upper cover and the lower cover; the blood inlet mandrel is located in the middle of the outer shell; the outer mandrel is located outside the blood inlet mandrel; the temperature-changing membrane is installed outside the outer mandrel; the temperature-changing temperature shell is located outside the temperature-changing membrane; The oxygen pressure membrane is located outside the temperature-changing housing and inside the housing; the upper cover and the lower cover are installed at the top and bottom of the housing, and the water inlet spacers in the upper cover and the lower cover are fixed to the temperature-changing housing through mortise and tenon joints; a blood channel is provided in the middle of the upper cover; the blood channel is fixedly connected to the blood inlet mandrel through mortise and tenon joints; the first blocking layer is installed on the upper part of the cavity between the blood inlet mandrel and the outer mandrel, the top of the temperature-changing membrane and the top of the oxygen pressure membrane; the second blocking layer is installed at the bottom of the temperature-changing membrane, the oxygen pressure membrane and the bottom of the cavity between the oxygen pressure membrane and the outer shell; one or more bleeding holes are provided on the outer core shaft and the temperature-changing shell; the centrifugal pump system comprises a blood inlet shell, a bleeding shell, an impeller and a lower shell; the impeller is fixed inside the blood inlet shell, and the bleeding shell is installed outside the blood inlet shell; the lower shell is fixedly installed below the blood inlet shell and the bleeding shell; a first blood channel is formed between the blood inlet shell and the impeller; one or more bleeding holes are provided on the blood inlet shell; a second blood channel is formed between the blood inlet shell and the bleeding shell; A third blood channel is formed between the oxygen pressure membrane and the shell.

2. A membrane oxygenator with a temperature-variable integrated centrifugal pump according to claim 1, characterized in that: The centrifugal pump system is installed at the bottom of the gas exchange device; the blood inlet shell is fixed on the blood inlet core shaft and is fixedly connected by mortise and tenon joints; the blood bleeding shell is fixed in the middle of the lower cover, and its top is fixedly connected to the outer core shaft by mortise and tenon joints; the centrifugal pump system and the gas exchange device are coaxially connected and installed.

3. The membrane oxygenator with a temperature-variable integrated centrifugal pump according to claim 1, characterized in that: The interior of the blood inlet core shaft is the upper part of the first blood channel; the upper part of the second blood channel is formed between the blood inlet core shaft and the outer core shaft.

4. The membrane oxygenator with a temperature-variable integrated centrifugal pump according to claim 1, characterized in that: The first blocking layer is installed on the upper part of the cavity between the blood inlet core shaft and the outer core shaft, the top of the variable temperature membrane and the top of the oxygen pressure membrane; the second blocking layer on the third blood channel is located at its bottom.

5. A membrane oxygenator with a temperature-variable integrated centrifugal pump according to claim 4, characterized in that: The blood inlet nozzle is located on the blood inlet core shaft and is connected to the first blood channel; the blood outlet nozzle is located on the outer shell and is connected to the third blood channel; the air inlet nozzle is located on the upper cover, on the outside of the water inlet spacer; the air outlet nozzle is located on the lower cover, on the outside of the water inlet spacer; the water inlet nozzle is located on the lower cover, on the inside of the water inlet spacer; The bleeding nozzle is located on the upper cover, on the inner side of the water inlet spacer.

6. The membrane oxygenator with a temperature-variable integrated centrifugal pump according to claim 2, characterized in that: The blood inlet core shaft, the outer core shaft, the temperature-changing chamber shell, the outer shell, the lower cover, the upper cover, the impeller, the blood inlet shell and the blood bleeding shell are all coaxially installed.

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