Fixtures for observing biological units
By designing a fixed device that includes rotary components and maintaining components, the problem of horizontal drift of samples in the existing technology in the microscope observation process is solved, and effective fixation and drift compensation for glass pieces are achieved, and the observation effect is improved.
Patent Information
- Application Number
- CN201811456621.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2018-11-30
- Publication Date
- 2025-01-24
- Estimated Expiration
- 2038-11-30
AI Technical Summary
In the prior art, the device used to fix the sample cannot effectively limit the horizontal drift of the sample during the microscope observation process, affecting the observation effect.
A fixing device including a screwing component and a holding component is designed. The screwing component clamps the glass slide through the screwing connection of the sleeve body and the cover body. The holding component is fixed on the observation platform through components such as piezoelectric plates and cylinders. Limit horizontal slide drift.
Effectively limited the horizontal drift of the relative observation platform, avoiding the effect of drift affected the observation effect, and compensation for drift through the driver of the voltage plate.
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Figure CN109975969B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of biological observation, and in particular to a fixing device for observing biological units. Background Art
[0002] In the prior art, in order to consider the versatility of fixing samples (the sample may be a glass slide with biological units such as cells) on the sample stage of a commonly used microscope, the device for fixing the sample usually adopts an elastic pressing plate fixing design or directly fixes the sample through the cooperation of clamps at both ends. The fixing accuracy is poor, and the sample is prone to drift during long-term observation, thereby affecting the observation effect.
[0003] In addition, in the prior art, the device for fixing the sample cannot compensate for the drift of the biological units (such as cells) in the sample, which will also affect the observation effect to a certain extent. Summary of the invention
[0004] In view of the above technical problems existing in the prior art, an embodiment of the present invention provides a fixing device for observing a biological unit.
[0005] In order to solve the above technical problems, the technical solution adopted in the embodiments of the present invention is:
[0006] A fixing device for observing biological units, which is used to fix a glass slide, the glass slide is used to place the biological unit, and the fixing device for observing biological units comprises a screwing assembly and a holding assembly;
[0007] The screw-on assembly comprises:
[0008] A sleeve body having an external thread;
[0009] The cover body has an external thread matching the internal thread and a hollow portion formed in the middle; wherein:
[0010] The cover body is screwed together with the internal thread and the external thread to clamp the glass slide between the cover body and the upper end of the sleeve body;
[0011] The screw-on assembly is fixed on the observation platform by means of the retaining assembly.
[0012] Preferably, an annular groove is formed at the upper end of the sleeve, and an elastic gasket is embedded in the annular groove so that the elastic gasket abuts against the edge of the glass slide.
[0013] Preferably, the retaining assembly comprises a piezoelectric plate, and the screw-on assembly is directly or indirectly fixed on the piezoelectric plate.
[0014] Preferably, the retaining assembly further comprises a base plate, and the base plate is fixed to the observation platform via fasteners; the piezoelectric plate is fixed to the base plate via fasteners.
[0015] Preferably, the retaining assembly further comprises a cylinder, and a stepped surface is formed at the lower end of the inner hole of the cylinder; wherein:
[0016] The piezoelectric plate is provided with a vertical through slot, and the cylinder extends into the through slot;
[0017] The screw-on assembly is located in the inner hole of the cylinder, and the stepped surface is used to support the bottom of the sleeve.
[0018] Preferably, a top screw is radially extended inward from the outside of the cylinder, and the head of the top screw is used to tighten the sleeve body.
[0019] Preferably, a flange is formed at the upper end of the cylinder, a pad is provided between the flange and the piezoelectric plate, the pad is fixed to the piezoelectric plate via fasteners, and the flange is fixed to the pad via fasteners.
[0020] Preferably, the through slot is a rectangular through slot.
[0021] Preferably, the lower end of the cylinder extends out of the bottom of the base plate, and the top screw passes through the portion of the cylinder extending out of the base plate.
[0022] Compared with the prior art, the fixing device for observing biological units of the present invention has the following beneficial effects: the present invention clamps the glass slide between the cover body and the sleeve body, thereby limiting the horizontal drift of the glass slide relative to the observation platform, so as to avoid the influence of the drift of the glass slide on the observation during the microscopic observation of biological cells. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 A front cross-sectional view of a fixing device for observing a biological unit provided by an embodiment of the present invention.
[0024] Figure 2 for Figure 1 An enlarged view of detail A.
[0025] Figure 3 for Figure 1 B view.
[0026] In the figure:
[0027] 10-screw-on assembly; 11-sleeve; 12-cover; 121-hollow portion; 13-elastic gasket; 20-holding assembly; 21-bottom plate; 22-piezoelectric plate; 221-through groove; 23-cylinder; 231-flange; 232-step surface; 24-pad; 25-top screw; 100-glass slide; 101-biological unit. DETAILED DESCRIPTION
[0028] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention is described in detail below in conjunction with the accompanying drawings and specific implementation methods.
[0029] like Figures 1 to 3 As shown, an embodiment of the present invention discloses a fixing device for observing a biological unit 101, which is used to fix a glass slide 100 carrying a biological unit 101 (e.g., a cell) on an observation platform for microscopic observation of the biological unit 101. The fixing device includes a screw assembly 10 and a retaining assembly 20. The screw assembly 10 is fixed to the observation platform by the retaining assembly 20. The screw assembly 10 is used to fix the glass slide 100. Figure 1 and Figure 2 As shown, the screw-on assembly 10 includes a sleeve 11 and a cover 12. An external thread is formed on the outer periphery of the sleeve 11, and an internal thread is formed on the inner side of the lower edge of the cover 12. The cover 12 is covered on the upper end of the sleeve 11 and is screwed together with the sleeve 11 through the cooperation of the internal thread and the external thread. The glass slide 100 is arranged between the upper end of the sleeve 11 and the cover 12 to be pressed by the cover 12 and the sleeve 11. The screw-on assembly 10 is fixed in the holding assembly 20, and the components of the holding assembly 20 are detachably fixedly connected and fixed to the observation platform by fasteners.
[0030] The present invention clamps the glass slide 100 between the cover body 12 and the sleeve body 11, thereby limiting the horizontal drift of the glass slide 100 relative to the observation platform, so as to avoid the influence of the drift of the glass slide 100 on the observation during the observation of biological cells under the microscope.
[0031] In order to prevent the glass slide 100 between the cover body 12 and the sleeve body 11 from being damaged by the compression of the cover body 12 and the sleeve body 11, in a preferred embodiment of the present invention, Figure 2 As shown, an annular groove is provided at the upper end of the sleeve 11, in which an elastic gasket 13 (or O-ring) is embedded, so that the cover 12 and the sleeve 11 form a certain pre-tightening force on the glass slide 100, and prevent the glass slide 100 from drifting horizontally by forming a friction force.
[0032] In a preferred embodiment of the present invention, the holding component 20 includes a piezoelectric plate 22, and the screwing component 10 can be fixed on the piezoelectric plate 22 directly or by other components in the holding component 20. In the present invention, the piezoelectric plate 22 is made of piezoelectric ceramics, which can move and deform according to electrical signals (this characteristic is common knowledge and will not be repeated here). The piezoelectric plate 22 allows the screwing component 10 to adjust its spatial position, which makes the piezoelectric plate 22 have the following advantages:
[0033] When the biological unit 101 drifts during observation of the biological unit 101 using a microscope, the piezoelectric plate 22 can drive the rotating assembly 10 to move to compensate for the drift of the biological unit 101 .
[0034] The following introduces other components of the retaining assembly 20 and a more preferred matching structure and method between the retaining assembly 20 and the screw-on assembly 10.
[0035] The retaining assembly 20 also includes a bottom plate 21, a pad 24, a cylinder 23 and a top screw 25. The bottom plate 21 is a rectangular plate. The bottom plate 21 is fixed on the observation platform by fasteners, and a through hole is opened in the middle of the bottom plate 21, and the through hole is a rectangular hole. The piezoelectric plate 22 is fixed to the middle of the bottom by fasteners, and a through groove 221 is opened in the middle of the piezoelectric plate 22, which is usually a rectangular through groove 221, so that the rectangular through groove 221 corresponds to the through hole. The cylinder 23 extends into the through groove 221, and the lower end of the cylinder 23 extends out of the bottom of the bottom plate 21. A stepped surface 232 (or stepped hole) is formed near the lower end of the inner hole of the cylinder 23. The screw-on assembly 10 is located in the inner hole of the cylinder 23. At this time, the stepped surface 232 is used to support the bottom of the sleeve 11. There are two top screws 25, and the two top screws 25 are radially penetrated through the sleeve 11 at the bottom and extend into the barrel 23 so that the heads of the top screws 25 are tightly against the outer peripheral surface of the sleeve 11. In this way, the screw assembly 10 will not have radial movement, so that the screw assembly 10 and the glass slide 100 can be fixed relative to the barrel 23. A flange 231 is formed at the upper end of the barrel 23, and a pad 24 is arranged between the flange 231 and the piezoelectric plate 22. The pad 24 is fixed to the piezoelectric plate 22 by fasteners, and the flange 231 is fixed to the pad 24 by fasteners. In this way, the barrel 23 and the piezoelectric plate 22 are fixedly connected. When it is necessary to compensate for the drift generated by the biological unit 101, the piezoelectric plate 22 drives the barrel 23 to move and then drives the glass slide 100 on the screw assembly 10 to move to complete the compensation of the drift.
[0036] It should be noted that a hollow portion 121 needs to be provided in the middle of the cover body 12 of the screw-on assembly 10 so that light can irradiate or pass through the biological unit 101 to observe the biological unit 101 .
[0037] The present invention uses the top screw 25 to tighten the sleeve 11 in the screw-on assembly 10 to fix the screw-on assembly 10 , which is equivalent to making an interference fit between the sleeve 11 and the cylinder 23 .
[0038] The above embodiments are only exemplary embodiments of the present invention and are not intended to limit the present invention. The protection scope of the present invention is defined by the claims. Those skilled in the art may make various modifications or equivalent substitutions to the present invention within the essence and protection scope of the present invention, and such modifications or equivalent substitutions shall also be deemed to fall within the protection scope of the present invention.
Claims
1. A fixing device for observing biological units, which is used to fix a glass slide, and the glass slide is used to place the biological unit, characterized in that: The fixing device for observing the biological unit includes a screw-on assembly and a retaining assembly; The screw-on assembly comprises: A sleeve body having an external thread; The cover body has an internal thread matching the external thread and a hollow portion formed in the middle; wherein: The cover body is screwed together with the internal thread and the external thread to clamp the glass slide between the cover body and the upper end of the sleeve body; The screw-on assembly is fixed on the observation platform by the retaining assembly; An annular groove is formed at the upper end of the sleeve, and an elastic gasket is embedded in the annular groove so that the elastic gasket abuts against the edge of the glass slide; The retaining component includes a piezoelectric plate, and the screw-on component is directly or indirectly fixed on the piezoelectric plate.
2. The fixing device for observing biological units according to claim 1, characterized in that: The retaining assembly also includes a base plate, which is fixed to the observation platform via fasteners; the piezoelectric plate is fixed to the base plate via fasteners.
3. The fixing device for observing biological units according to claim 2, characterized in that: The retaining assembly further comprises a cylinder, and a stepped surface is formed at the lower end of the inner hole of the cylinder; wherein: The piezoelectric plate is provided with a vertical through slot, and the cylinder extends into the through slot; The screw-on assembly is located in the inner hole of the cylinder, and the stepped surface is used to support the bottom of the sleeve.
4. The fixing device for observing biological units according to claim 3, characterized in that: A jack screw is radially extended inward from the outer side of the cylinder, and the head of the jack screw is used for tightening the sleeve body.
5. The fixing device for observing biological units according to claim 3 or 4, characterized in that: A flange is formed at the upper end of the cylinder, a pad is provided between the flange and the piezoelectric plate, the pad is fixed to the piezoelectric plate via a fastener, and the flange is fixed to the pad via a fastener.
6. The fixing device for observing biological units according to claim 3 or 4, characterized in that: The through slot is a rectangular through slot.
7. The fixing device for observing biological units according to claim 4, characterized in that: The lower end of the cylinder extends out of the bottom of the bottom plate, and the top screw passes through the portion of the cylinder extending out of the bottom plate.
Citation Information
Patent Citations
Fixing device for observing biological unit
CN209148956U