A chemiluminescence reading device applied to a turntable platform

By setting up a sealing and interpretation mechanism on the turntable platform, sealing and interpretation of the reaction cup position is solved, and the problems of equipment control complexity and space occupation in the prior art are improved, experimental efficiency is improved and photomultiplier tubes are protected.

CN110609031BActive Publication Date: 2024-12-27AIKANG MEDTECH CO LTD
View PDF 6 Cites 0 Cited by

Patent Information

Application Number
CN201911044859.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2019-10-30
Publication Date
2024-12-27
Estimated Expiration
2039-10-30

AI Technical Summary

Technical Problem

In fully automatic chemiluminescence immunoassay, the existing technology requires the interpretation of results in a closed dark room, resulting in increased equipment control complexity and excessive platform space occupation, and the inability to directly interpret the reaction cup on the turntable, affecting the experiment efficiency.

Method used

Design a chemiluminescence interpretation device applied to a rotary platform. By setting up a sealing mechanism and a judgment mechanism on the rotary disk, sealing and interpretation of the reaction cup position is realized, and the rotation and interpretation window of the rotary disk are used to complete the interpretation, reducing transfer steps and saving Equipment platform space.

Benefits of technology

The interpretation of the reaction cup is achieved directly on the turntable, which reduces experimental steps, improves experimental efficiency, saves the space of the equipment platform, and protects the photomultiplier tube through the interpretation head light blocking mechanism, reducing the damage to the light.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN110609031B_ABST
    Figure CN110609031B_ABST
Patent Text Reader

Abstract

The present invention relates to the technical field of fully automatic chemiluminescence immunoassay analyzers, and discloses a chemiluminescence interpretation device applied to a turntable platform, including a turntable, reaction cup positions are arranged at equal angles along the circumference of the turntable, and interpretation windows corresponding to and connected to the reaction cup positions are arranged at equal angles on the outer circumferential side of the turntable, a sealing mechanism is arranged on the turntable, the axis of the sealing mechanism and the axis of the reaction cup position are located on the same circumferential surface, the sealing mechanism can move up and down along its axis direction to seal or open the reaction cup position, and an interpretation mechanism is arranged on the side of the turntable, and the interpretation mechanism can move along the diameter direction of the turntable and complete the interpretation through the interpretation window. The purpose of the present invention is to provide a chemiluminescence interpretation device applied to a turntable platform, which is used to interpret the chemiluminescence experiment results on the turntable platform, reduce the transfer steps, improve the experimental efficiency, and save the equipment platform space.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the technical field of fully automatic chemiluminescence immunoassay analyzers, and in particular to a chemiluminescence interpretation device applied to a turntable platform. Background Art

[0002] When the fully automatic chemiluminescence immunoassay analyzer interprets the results, it needs to be done in a closed darkroom to ensure the accuracy of the interpretation results. Therefore, in the design of the fully automatic chemiluminescence immunoassay analyzer, a special darkroom for interpretation is usually set up and the reaction cup is transferred to the darkroom for interpretation. Before interpretation, a step of transferring the reaction cup by a robotic arm is required, which increases the experimental process and the complexity of equipment control. At the same time, the darkroom used for interpretation requires a larger platform space for the equipment to meet the experimental requirements.

[0003] The purpose of using a turntable platform for chemiluminescence experiments is to reduce the number of transfer steps and improve experimental efficiency. This requires a device that can directly read the reaction cups on the turntable to fully utilize the advantages of the turntable chemiluminescence experimental platform. Summary of the invention

[0004] The object of the present invention is to provide a chemiluminescence interpretation device applied to a turntable platform, which is used to interpret the chemiluminescence experiment results on the turntable platform, reduce the transfer steps, improve the experimental efficiency, and save the equipment platform space.

[0005] The present invention is realized through the following technical scheme: a chemiluminescence interpretation device applied to a turntable platform comprises a turntable, reaction cup positions are arranged at equal angles along the circumference of the turntable, interpretation windows corresponding to and connected with the reaction cup positions are arranged at equal angles on the outer circumferential side of the turntable, a sealing mechanism is arranged on the turntable, the axis of the sealing mechanism and the axis of the reaction cup position are located on the same circumferential plane, the sealing mechanism can move up and down along the axis direction thereof to seal or open the reaction cup position, and an interpretation mechanism is arranged on the side of the turntable, the interpretation mechanism can move along the diameter direction of the turntable and complete the interpretation through the interpretation window.

[0006] In the above-mentioned chemiluminescence interpretation device, the reaction cup is placed in the reaction cup position and is transmitted to the station of each experimental step through the rotation of the turntable to complete the corresponding experimental step. When the reaction cup that needs to be interpreted reaches the interpretation station through the rotation of the turntable, the sealing mechanism moves along the axis of the reaction cup position where the reaction cup is located until the axial seal of the reaction cup position is achieved. The interpretation mechanism reaches the interpretation window along the diameter direction of the turntable and covers the interpretation window, making the reaction cup position a completely sealed darkroom, thereby achieving the conditions required for interpretation and enabling the interpretation mechanism to complete the interpretation steps directly at the reaction cup position on the turntable, thereby reducing the equipment platform space.

[0007] Furthermore, the reading mechanism includes a reading drive mechanism and a reading transmission mechanism, a reading module is installed on the reading transmission mechanism, the reading module includes a reading base plate, a probe bracket is installed on the reading base plate, a probe cover is installed on the probe bracket, a photomultiplier tube is installed on the left side of the probe cover, a reading probe is installed on the right side, a gasket is installed on the other end of the reading probe, the reading probe passes through the reading base plate and extends outward, a reading bracket is provided on the side of the reading module, the bottom of the reading bracket is fixed to the side of the reading transmission mechanism, a reading head light blocking mechanism is installed in front of the reading module, and the reading head light blocking mechanism is fixed on the reading bracket. Its function is to realize the movement of the reading module in the diameter direction of the turntable through the reading transmission mechanism. When the reading module is not working, the reading module moves away from the reading window along the diameter direction of the turntable, and the reading head light blocking mechanism covers the reading probe, thereby protecting the photomultiplier tube from light, reducing the damage of light to the photomultiplier tube and the influence of sensitivity. The gasket on the reading probe can fit tightly with the reading window to prevent the gap from leaking and affecting the reading effect.

[0008] Furthermore, the light blocking mechanism of the reading head includes a baffle base, a baffle driving motor is installed on the baffle base, the output shaft of the baffle driving motor passes through the baffle base and extends to the front of the baffle base, a baffle is installed on the output shaft of the baffle driving motor, a baffle photoelectric switch sensing sheet is installed on the baffle, a baffle photoelectric switch is installed on the baffle base, when the baffle photoelectric switch sensing sheet rotates, one end of the baffle photoelectric switch sensing sheet can enter the sensing area of ​​the baffle photoelectric switch, a reading hole is provided on the baffle base for the reading module to pass through for reading, the reading hole can be opened and closed when the baffle rotates, and a baffle isolation sheet is installed in front of the reading hole. Its function is: the baffle is driven to rotate by the motor output shaft, and the reading hole is opened and closed by the rotation of the baffle, when reading is required, the baffle rotates to open the reading hole, and when reading is not required, the baffle rotates to close the reading hole.

[0009] The transmission mechanism further comprises a support seat, a reading driving motor is installed at the lower end of the support seat, the reading transmission mechanism is connected to the support seat, a driving wheel is installed on the output shaft of the reading driving motor, a driven wheel is installed at the upper end of the support seat, and a synchronous belt is installed between the driving wheel and the driven wheel. The reading transmission mechanism comprises a transmission mechanism base, a transmission guide rail is installed on the transmission mechanism base, a slider is installed on the transmission guide rail, a fixed slide is installed above the slider, a screw rod passes through the middle of the fixed slide, one end of the screw rod passes through the support seat and is connected to the driven wheel and can rotate synchronously with the rotation of the driven wheel, a screw rod nut is installed on the screw rod, the screw rod nut is fixed on the fixed slide, a support plate is installed at one end of the transmission mechanism base, and the other end of the screw rod is fixed on the support plate. A photoelectric switch is installed on the side of the support seat facing the fixed slide, and a sensor sheet is installed at the position of the fixed slide corresponding to the photoelectric switch. When the fixed slide moves to the extreme position toward the support seat, one end of the sensor sheet enters the sensing area of ​​the photoelectric switch. Its function is to make the transmission process of the judgment module smooth, and after the judgment is completed, it can sense the reset action of the judgment module, so as to immediately feedback the information to the judgment head light blocking mechanism after the judgment module is reset, so that the judgment head light blocking mechanism can block the light of the judgment module as soon as possible, thereby reducing the damage of light to the photomultiplier tube and the impact on sensitivity.

[0010] As an improvement to the sealing mechanism of the present invention, when the reaction cup position is a blind hole, the sealing mechanism includes a sealing drive motor seat, a sealing drive motor is installed behind the sealing drive motor seat, one or two rack limit seats are installed in front of the sealing drive motor seat, a first rack that can slide therein is provided in the rack limit seat, a gear is installed on the output shaft of the sealing drive motor, the gear is meshed with the first rack, a connecting seat is installed on the upper end of the first rack, an upper sealing assembly is installed below the connecting seat, and when the upper sealing assembly moves downward to the limit position, the upper end of the reaction cup position can be closed, a left induction sheet is installed on the first rack, a left photoelectric switch is installed on the left side of the sealing drive motor seat, and when the first rack moves downward to the limit position, the left induction sheet enters the sensing area of ​​the left photoelectric switch. Its function is: the sealing mechanism is arranged above and below the platform, and the space above and below the equipment turntable platform is fully utilized. During the interpretation process, the sealing mechanism seals the reaction cup position to create a darkroom environment required for interpretation, without the need to set up an additional darkroom device for interpretation.

[0011] As another improvement to the sealing mechanism described in the present invention, when the reaction cup position is a through hole, the sealing mechanism includes a sealing drive motor seat, a sealing drive motor is installed on the rear side of the sealing drive motor seat, two or four rack limit seats are symmetrically installed on the front side of the sealing drive motor seat, a first rack that can slide therein is provided in the rack limit seat on the left, and a second rack that can slide therein is provided in the rack limit seat on the right, the first rack and the second rack are arranged in parallel, a gear is installed on the output shaft of the sealing drive motor, the gear is located between the first rack and the second rack and meshes with the first rack and the second rack, a connecting seat is installed on the upper end of the first rack, an upper sealing assembly is installed below the connecting seat, and the upper end of the second rack is installed The upper sealing assembly is connected to the lower sealing assembly, a left induction sheet is installed on the first rack, a right induction sheet is installed on the second rack, a left photoelectric switch is installed on the left side of the sealing drive motor seat, and a right photoelectric switch is installed on the right side of the sealing drive motor seat. When the gear rotates counterclockwise, the upper sealing assembly and the lower sealing assembly move relative to each other along the same axis and can reach the upper and lower end surfaces of the reaction cup position at the same time, so as to realize the sealing of the upper and lower ends of the reaction cup position of the through hole. When the reaction cup position is in a sealed state, the right induction sheet is located in the sensing area of ​​the right photoelectric switch. When the upper sealing assembly and the lower sealing assembly leave the reaction cup position, when the upper sealing assembly reaches the upper limit position, the lower sealing assembly reaches the lower limit position, and the left induction sheet is located in the sensing area of ​​the left photoelectric switch. Its function is: the first rack and the second rack are parallel to each other and are respectively located on both sides of the gear, so that when the gear rotates, the first rack and the second rack can move in opposite directions at the same time, which speeds up the sealing speed and also ensures the synchronization of the movement of the upper sealing component and the lower sealing component. At the same time, the setting of the right sensor plate and the right photoelectric switch can detect and feedback the sealing state of the reaction cup position, and the setting of the left sensor plate and the left photoelectric switch can detect and feedback the extreme positions of the upper sealing component and the lower sealing component away from the reaction cup position, thereby ensuring the accuracy of the experimental process control.

[0012] Further, the upper sealing assembly includes an upper guide base, an upper sealing guide sleeve is installed on the upper guide base, a first spring is arranged in the upper sealing guide sleeve, a sealing cover is installed in the front end of the upper sealing guide sleeve, the upper end of the sealing cover has a certain sliding space in the sealing guide sleeve, and the two ends of the first spring are in contact with the upper guide base and the top of the sealing cover respectively; the lower sealing assembly includes a lower guide base, a lower sealing guide sleeve is installed on the lower guide base, a second spring is arranged in the lower sealing guide sleeve, a sealing bracket is installed on the lower sealing guide sleeve, a sealing gasket is arranged on the sealing bracket, the sealing gasket is fixed to the sealing bracket by bonding, the lower end of the sealing bracket has a certain sliding space in the lower sealing guide sleeve, and the two ends of the second spring are in contact with the bottom of the lower guide base and the sealing bracket respectively. Its function is that the setting of the first spring and the second spring can make the upper sealing assembly and the lower sealing assembly have a certain degree of adaptability when sealing the reaction cup position, so as to ensure the sealing effect.

[0013] Furthermore, the upper end of the first rack is an optical axis, a bushing is installed on the optical axis, the outer ring of the bushing is fixed on the connecting block, and the other end of the connecting block is fixed on the reading bracket. Its function is to prevent the first rack from shaking during movement and ensure accurate positioning during the sealing process.

[0014] In summary, the chemiluminescence interpretation device applied to the turntable platform provided by the present invention has the following beneficial effects:

[0015] The present invention provides a chemiluminescence reading device applied to a turntable platform, which can seal the reaction cup position on the turntable through a sealing mechanism. When the reading mechanism reads through the reading window, the gasket on the reading probe seals the reading window, so that the reaction cup position reaches a darkroom environment, thereby realizing the direct reading of the reaction cup on the reaction cup position on the turntable.

[0016] Before completing or starting the interpretation, the baffle in the light shielding mechanism of the interpretation head closes the interpretation hole, so that the interpretation probe is in a sealed light-proof environment, thereby shielding the photomultiplier tube from light, reducing the damage of light to the photomultiplier tube and the impact on sensitivity, and isolating dust in the environment. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 The figure is a schematic structural diagram of a chemiluminescence interpretation device applied to a turntable platform according to the present invention.

[0018] Figure 2 It is a structural schematic diagram of the interpretation mechanism of the present invention.

[0019] Figure 3 This is a schematic diagram of the structure of the light shielding mechanism of the reading head sealing the reading probe according to the present invention.

[0020] Figure 4 It is a schematic diagram of the working state structure of the judgment module of the present invention.

[0021] Figure 5 It is a schematic diagram of the structure of the reading drive mechanism and the reading transmission mechanism of the present invention.

[0022] Figure 6 It is a schematic structural diagram of the sealing mechanism in the first embodiment of the present invention.

[0023] Figure 7 Schematic diagram of the structure of the sealing mechanism in the second embodiment of the present invention.

[0024] Figure 8 It is a schematic structural diagram of the upper sealing assembly described in the present invention.

[0025] Fig. 9It is a schematic structural diagram of the lower sealing assembly described in the present invention.

[0026] Among them, 1-reading mechanism, 11-reading transmission mechanism, 110-transmission mechanism base, 111-transmission guide rail, 112-slider, 113-support seat, 114-photoelectric switch, 115-screw, 116-sensing sheet, 117-screw nut, 118-fixed slide, 119-support plate, 12-reading module, 121-probe bracket, 122-probe cover, 123-photomultiplier tube, 124-reading probe, 125-reading bottom plate, 126-washer, 13-reading head light blocking mechanism, 131-baffle drive motor, 132-baffle base, 133-baffle photoelectric switch, 134-baffle photoelectric switch sensing sheet, 135-baffle, 136-baffle isolation sheet, 137-reading hole, 14-reading drive mechanism, 141-reading drive motor, 142-driving wheel, 143-same Step belt, 144-driven wheel, 15-reading bracket, 2-sealing mechanism, 201-upper sealing assembly, 2011-upper guide base, 2012-upper sealing guide sleeve, 2013-first spring, 2014-sealing cover, 202-lower sealing assembly, 2021-lower guide base, 2022-lower sealing guide sleeve, 2023-second spring, 2024-sealing bracket, 2025-sealing pad, 203-connecting seat, 204-first rack, 205-second rack, 206-sealing drive motor seat, 207-sealing drive motor, 208-gear, 209-rack limit seat, 210-right induction plate, 211-right photoelectric switch, 212-bushing, 213-left induction plate, 214-left photoelectric switch, 3-connecting block, 4-turntable, 41-reading window, 42-reaction cup position, 5-reaction cup. DETAILED DESCRIPTION

[0027] To explain the technical features and achieved purposes and effects of the present invention in detail, further description is given below in conjunction with the accompanying drawings:

[0028] like Figures 1 to 8 As shown, a chemiluminescence interpretation device applied to a turntable platform comprises a turntable 4, on which cuvette positions 42 are arranged at equal angles along the circumference, and interpretation windows 41 corresponding to and connected with the cuvette positions 42 are arranged at equal angles on the outer circumferential side of the turntable 4, a sealing mechanism 2 is arranged on the turntable 4, the axis of the sealing mechanism 2 and the axis of the cuvette positions 42 are located on the same circumferential plane, the sealing mechanism 2 can move up and down along its axis direction to seal or open the cuvette positions 42, and an interpretation mechanism 1 is arranged on the side of the turntable 4, and the interpretation mechanism 1 can move along the diameter direction of the turntable 4 and complete the interpretation through the interpretation window 41.

[0029] Preferably, the reading mechanism 1 includes a reading drive mechanism 14 and a reading transmission mechanism 11, a reading module 12 is installed on the reading transmission mechanism 11, the reading module 12 includes a reading base plate 125, a probe bracket 121 is installed on the reading base plate 125, a probe cover 122 is installed on the probe bracket 121, a photomultiplier tube 123 is installed on the left side of the probe cover 122, and a reading probe 124 is installed on the right side, the reading probe 124 passes through the probe bracket 121 and extends outward, a reading bracket 15 is provided on the side of the reading module 12, the bottom of the reading bracket 15 is fixed to the side of the reading transmission mechanism 11, a reading head light blocking mechanism 13 is installed in front of the reading module 12, and the reading head light blocking mechanism 13 is fixed on the reading bracket 15.

[0030] Preferably, the reading head light blocking mechanism 13 includes a baffle base 132, on which a baffle driving motor 131 is installed, the output shaft of the baffle driving motor 131 passes through the baffle base 132 and extends to the front of the baffle base 132, a baffle 135 is installed on the output shaft of the baffle driving motor 131, the driving motor 131 can control the baffle 135 to rotate to open and close the reading hole 137, a baffle photoelectric switch sensing sheet 134 is installed on the baffle 135, and a baffle photoelectric switch 133 is installed on the baffle base 132, when the baffle photoelectric switch sensing sheet 134 rotates with the baffle 135, one end of the baffle photoelectric switch sensing sheet 134 can enter the sensing area of ​​the baffle photoelectric switch 133, and a reading hole 137 is opened on the baffle base 132 for the reading module 12 to pass through for reading, and a baffle isolation sheet 136 is installed in front of the reading hole 137.

[0031] Preferably, the reading drive mechanism 14 includes a reading drive motor 141, which is mounted on the lower end of a support seat 113, the support seat 113 is connected to the reading transmission mechanism 11, a driving wheel 142 is mounted on the output shaft of the reading drive motor 141, a driven wheel 144 is provided at the upper end of the support seat 113, a synchronous belt 143 is installed between the driving wheel 142 and the driven wheel 144, the reading transmission mechanism 11 includes a transmission mechanism base 110, a transmission guide rail 111 is mounted on the transmission mechanism base 110, a slider 112 is mounted on the transmission guide rail 111, a fixed slide seat 118 is mounted above the slider 112, a screw rod 115 runs through the middle of the fixed slide seat 118, and the screw rod 115 runs through the middle of the screw rod 115. One end of 15 passes through the support seat 113 and is connected to the driven wheel 144 and can rotate synchronously with the rotation of the driven wheel 144. A screw nut 117 is installed on the screw rod 115, and the screw nut 117 is fixed on the fixed slide 118. A support plate 119 is installed on one end of the transmission mechanism base 110, and the other end of the screw rod 115 is fixed on the support plate 119. A photoelectric switch 114 is installed on the side of the support seat 113 facing the fixed slide 118, and a sensor sheet 116 is installed at the position of the fixed slide 118 corresponding to the photoelectric switch 114. When the fixed slide 118 moves to the extreme position toward the support seat 113, one end of the sensor sheet 116 enters the sensing area of ​​the photoelectric switch 117.

[0032] like Figure 6 As shown, in one embodiment, the reaction cup position 42 is a through hole, which is unobstructed up and down, and the sealing mechanism 2 includes a sealing drive motor seat 206, a sealing drive motor 207 is installed on the rear side of the sealing drive motor seat 206, and two or four rack limit seats 209 are symmetrically installed on the front side of the sealing drive motor seat 206, a first rack 204 that can slide therein is provided in the rack limit seat 209 on the left side, and a second rack 205 that can slide therein is provided in the rack limit seat 209 on the right side, and the first rack 204 and the second rack 205 are arranged in parallel, and the sealing drive motor A gear 208 is installed on the output shaft 207, and the gear 208 is located between the first rack 204 and the second rack 205 and meshes with the first rack 204 and the second rack 205. A connecting seat 203 is installed on the upper end of the first rack 204, and an upper sealing component 201 is installed below the connecting seat 203. A lower sealing component 202 is installed on the upper end of the second rack 205. When the gear 208 rotates counterclockwise, the upper sealing component 201 and the lower sealing component 202 move relative to each other along the same axis and can reach the upper and lower end surfaces of the reaction cup position 42 at the same time, thereby realizing the sealing of the upper and lower ends of the reaction cup position 42 of the through hole.

[0033] Preferably, the lower sealing assembly 202 includes a lower guide base 2021, on which a lower sealing guide sleeve 2022 is installed, in which a second spring 2023 is provided, and a sealing bracket 2024 is installed on the lower sealing guide sleeve 2022, on which a sealing gasket 2025 is provided, which is fixed to the sealing bracket 2024 by bonding, and the lower end of the sealing bracket 2024 has a certain sliding space in the lower sealing guide sleeve 2022, and the two ends of the second spring 2023 are in contact with the bottom of the lower guide base 2021 and the sealing bracket 2024, respectively.

[0034] Preferably, the upper sealing assembly 201 includes an upper guide base 2011, on which an upper sealing guide sleeve 2012 is installed, a first spring 2013 is provided in the upper sealing guide sleeve 2012, a sealing cover 2014 is installed at the front end of the upper sealing guide sleeve 2012, the upper end of the sealing cover 2014 has a certain sliding space in the sealing guide sleeve 2012, and the two ends of the first spring 2013 are in contact with the upper guide base 2011 and the top of the sealing cover 2014 respectively.

[0035] Preferably, the upper end of the first rack 204 is an optical axis 2041 , a bushing 212 is mounted on the optical axis 2041 , an outer ring of the bushing 212 is fixed on the connecting block 3 , and the other end of the connecting block 3 is fixed on the reading bracket 15 .

[0036] The chemiluminescence reading device provided in the above embodiment has the following specific implementation steps:

[0037] During the experiment, the reaction cup 5 used as the experimental carrier is placed in the reaction cup position 42, and reaches the station of other experimental steps as the turntable 4 rotates to complete other experimental steps. When other experimental steps are completed, the reaction cup 5 that needs to be interpreted reaches the interpretation station as the turntable 4 rotates.

[0038] When the reaction cup 5 arrives at the reading station, the sealing drive motor seat 207 rotates counterclockwise, driving the gear 208 to rotate counterclockwise, the first rack 204 meshing therewith moves downward, and the second rack 205 meshing therewith moves upward synchronously, and the upper sealing component 201 and the lower sealing component 202 move relative to each other along the central axis direction until they reach the upper and lower end surfaces of the reaction cup position 42, and the upper and lower end surfaces of the reaction cup position 42 are completely sealed by the sealing cover 2014 of the upper sealing component 201 and the sealing gasket 2025 of the lower sealing component 202. At this time, the positions of the upper sealing component 201 and the lower sealing component 202 are respectively their respective lower limit positions and upper limit positions. At this time, the left induction sheet 213 is away from the induction area of ​​the left photoelectric switch 214, and the right induction sheet 210 enters the induction area of ​​the right photoelectric switch 211. The right photoelectric switch 211 feeds back the induction signal. At this time, the reading mechanism 1 starts to work, and the baffle drive motor 131 rotates counterclockwise, as shown in FIG. Figure 4 As shown, the baffle 135 rotates accordingly to open the reading hole 137 (in the non-reading state, such as Figure 3 As shown, the baffle 135 closes the reading hole 137, that is, covers the reading hole 137, and the baffle photoelectric switch sensor sheet 134 rotates with the baffle 135 and leaves the sensing area of ​​the baffle photoelectric switch 133. The baffle photoelectric switch 133 feeds back the sensing signal, and the reading drive motor 141 starts to rotate, and the driving wheel 142 rotates accordingly, and drives the driven wheel 144 to rotate through the synchronous belt 143. The screw 115 fixed on the driven wheel 144 rotates synchronously with the driven wheel 144, and the screw nut 117 starts to rotate along the screw axial direction. The reading module 12 moves and drives the fixed slide 118 installed on the slide block 112 to slide. Since the reading module 12 is installed on the conveying mechanism 11, at this time, the reading module 12 moves along the conveying guide rail 111 toward the reading window 41, and the reading probe 124 extends outward through the opened reading hole 137 to the position of the reading window 41. The gasket 126 on the reading module 12 is tightly matched with the reading window 41 to form a completely enclosed darkroom environment in the middle of the reaction cup position 42, so that the reading module completes the reading of the reaction cup 5 in the reaction cup position 42.

[0039] After the reading module 12 completes the reading, the reading drive motor 141 performs reverse rotation driving, driving the reading transmission mechanism 11 to perform reverse movement, thereby causing the reading module 12 to move in the direction away from the reading window 41. When the reading module 12 is completely reset, the sensing sheet 116 on the fixed slide 118 enters the sensing area of ​​the photoelectric switch 114, and the photoelectric switch 114 feeds back the sensing signal. The baffle driving motor 131 rotates clockwise, and the baffle 135 rotates accordingly, thereby closing the reading hole 137. The sealing drive motor 207 rotates in the opposite direction, and the first rack 204 and the second rack 205 move in opposite directions away from the upper and lower end surfaces of the reaction cup position 42. When the upper sealing assembly 201 and the lower sealing assembly 202 leave the reaction cup position 42 and return to the initial position, that is, when the upper sealing assembly 201 reaches the upper limit position, the lower sealing assembly 202 reaches the lower limit position, and the left sensing sheet 214 enters the sensing area of ​​the left photoelectric switch 213, and the left photoelectric switch 213 feeds back the sensing signal.

[0040] When the next reaction cup 5 needs to be read, the turntable 4 rotates to transfer the corresponding reaction cup 5 to the reading position, and the sealing mechanism 2 and the reading mechanism 1 repeat the above steps until the reading of all reaction cups 5 is completed.

[0041] like Figure 7 As shown, in another embodiment, the reaction cup position 42 is a blind hole, and the sealing mechanism 2 includes a sealing drive motor seat 206', a sealing drive motor 207 is installed behind the sealing drive motor seat 206', and one or two rack limit seats 209 are installed in front of the sealing drive motor seat 206'. The rack limit seat 209 is provided with a first rack 204 that can slide therein, and a gear 208 is installed on the output shaft of the sealing drive motor 207, and the gear 208 is meshed with the first rack 204. The upper end of the first rack 204 is installed with a connecting seat 203, and the upper sealing component 201 is installed below the connecting seat 203. When the upper sealing component 201 moves downward to the limit position, the upper end of the reaction cup position 42 can be closed. The first rack 204 is installed with a left sensing piece 214', and the left side of the sealing drive motor seat 206 is installed with a left photoelectric switch 213'. When the first rack 204 moves downward to the limit position, the left sensing piece 214' enters the sensing area of ​​the left photoelectric switch 213'.

[0042] When the reaction cup position 42 is a blind hole, the sealing mechanism 2 only needs to perform one-way sealing on the upper part when sealing the reaction cup position 42. During the sealing process, the upper sealing component 201 moves downward along its axial direction until the upper end of the reaction cup position 42 is completely sealed. At this time, the left sensing sheet 214' enters the sensing area of ​​the left photoelectric switch 213', and the left photoelectric switch 213' feeds back the sensing signal, and the reading mechanism 1 starts to work.

[0043] In the above embodiment, the sealing mechanism 2 occupies a smaller space on the equipment platform, and most of its working parts are located above or below the equipment platform, making full use of the space above and below the equipment platform. The first rack 204 extends from the bottom of the equipment platform to the top of the equipment platform, and its upper end is designed as an optical axis 2041. A bushing 212 is installed on the optical axis and a connecting block 3 is provided outside the bushing 212 to connect with the reading bracket 15. This can prevent the first rack 204 from shaking during the up and down movement, resulting in inaccurate positioning during the sealing process.

[0044] During the sealing process, the upper sealing component 201 enters the upper part of the reaction cup position 42, and the sealing cover 2014 covers the reaction cup 5. The elastic force of the first spring 2013 makes the sealing process have a buffering and adaptive process, so that the upper part of the reaction cup position 42 is in a completely sealed state.

[0045] When the reaction cup position 42 is a through hole, the upper sealing component 201 seals the upper part of the reaction cup position 42, and the lower sealing component 202 seals the lower part of the reaction cup position 42. The lower sealing component 202 enters the lower part of the reaction cup position 42. The elastic force of the second spring 2023 makes the sealing process have a buffering and adaptive process, so that the lower part of the reaction cup position 42 is in a completely sealed state.

[0046] In summary, the chemiluminescence interpretation device applied to a turntable platform provided by the present invention can create a darkroom environment required for single-hole interpretation on the turntable 4 through a sealing mechanism 2, and the interpretation module 12 completes the interpretation of a single reaction cup 5 through the interpretation window 41, and through the rotation of the turntable 4, the reaction cup 5 in each reaction cup position 42 can be directly interpreted on the turntable, thereby reducing the transfer steps of the reaction cup, improving the experimental efficiency, and saving the equipment platform space.

[0047] At the same time, when no interpretation is required, the photomultiplier tube 123 is shielded from light by the interpretation light shielding mechanism 13 to effectively protect the photomultiplier tube 123, reduce the damage of light in the external environment to the photomultiplier tube and the influence of sensitivity, and ensure the stability of the interpretation module.

[0048] The applicant declares that the above-described embodiments only express the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above-described embodiments, and the above-described embodiments and the specification only describe the principles of the present invention. For those skilled in the art, various changes and improvements can be made without departing from the concept and scope of the present invention, and these changes and improvements all fall within the scope of the present invention to be protected.

[0049] The present invention is not limited to the above-mentioned embodiments, and all embodiments that use structures and methods similar to the present invention to achieve the purpose of the present invention are within the protection scope of the present invention.

Claims

1. A chemiluminescence reading device applied to a turntable platform, characterized in that: The invention comprises a rotating disk, reaction cup positions are arranged at equal angles along the same circumference of the rotating disk, and interpretation windows corresponding to and connected with the reaction cup positions are arranged at equal angles on the outer circumferential side of the rotating disk, a sealing mechanism is arranged on the rotating disk, the axis of the sealing mechanism and the axis of the reaction cup positions are located on the same circumferential surface, the sealing mechanism can move up and down along the axis direction thereof to seal or open the reaction cup positions, and an interpretation mechanism is arranged on the side of the rotating disk, and the interpretation mechanism can move along the diameter direction of the rotating disk and complete interpretation through the interpretation window; The reading mechanism includes a reading drive mechanism and a reading transmission mechanism, a reading module is installed on the reading transmission mechanism, the reading module includes a reading bottom plate, a probe bracket is installed on the reading bottom plate, a probe cover is installed on the probe bracket, a photomultiplier tube is installed on the left side of the probe cover, and a reading probe is installed on the right side, the reading probe passes through the reading bottom plate and extends outward, a reading head light blocking mechanism is installed in front of the reading module, a reading bracket is provided on the side of the reading module, and the bottom of the reading bracket is fixed to the side of the reading transmission mechanism; The light blocking mechanism of the reading head includes a baffle base, a baffle driving motor is installed on the baffle base, the output shaft of the baffle driving motor passes through the baffle base and extends to the front of the baffle base, a baffle is installed on the output shaft of the baffle driving motor, a baffle photoelectric switch sensing sheet is installed on the baffle, and a baffle photoelectric switch is installed on the baffle base. When the baffle photoelectric switch rotates, one end of the baffle photoelectric switch can enter the sensing area of ​​the baffle photoelectric switch. A reading hole for the reading module to pass through for reading is opened on the baffle base. When the baffle rotates, the reading hole can be opened and closed, and a baffle isolation sheet is installed in front of the reading hole. The reading driving mechanism comprises a supporting seat, a reading driving motor is installed at the lower end of the supporting seat, the supporting seat is connected to the reading transmission mechanism, a driving wheel is installed on the output shaft of the reading driving motor, a driven wheel is installed at the upper end of the supporting seat, and a synchronous belt is installed between the driving wheel and the driven wheel. The reading transmission mechanism comprises a transmission mechanism base, a transmission guide rail is installed on the transmission mechanism base, a slider is installed on the transmission guide rail, a fixed slide is installed above the slider, a screw rod passes through the middle of the fixed slide, one end of the screw rod passes through the supporting seat and is connected to the driven wheel and can rotate synchronously with the rotation of the driven wheel, a screw rod nut is installed on the screw rod, the screw rod nut is fixed on the fixed slide, a support plate is installed at one end of the transmission mechanism base, and the other end of the screw rod is fixed on the support plate. A photoelectric switch is installed on the side of the supporting seat facing the fixed slide, and a sensing sheet is installed at the position of the fixed slide corresponding to the photoelectric switch. When the fixed slide moves to the extreme position toward the support seat, one end of the sensing sheet enters the sensing area of ​​the photoelectric switch.

2. The chemiluminescence interpretation device applied to a turntable platform according to claim 1, characterized in that: The reaction cup position is a blind hole, and the sealing mechanism includes a sealing drive motor seat, a sealing drive motor is installed behind the sealing drive motor seat, one or two rack limit seats are installed in front of the sealing drive motor seat, a first rack that can slide therein is provided in the rack limit seat, a gear is installed on the output shaft of the sealing drive motor, the gear is meshed with the first rack, a connecting seat is installed on the upper end of the first rack, an upper sealing assembly is installed below the connecting seat, and the upper end of the reaction cup position can be closed when the upper sealing assembly moves downward to the extreme position, a left sensor sheet is installed on the first rack, and a left photoelectric switch is installed on the left side of the sealing drive motor seat, and when the first rack moves downward to the extreme position, the left sensor sheet enters the sensing area of ​​the left photoelectric switch.

3. The chemiluminescence interpretation device applied to a turntable platform according to claim 1, characterized in that: The reaction cup position is a through hole, and the sealing mechanism includes a sealing drive motor seat, a sealing drive motor is installed behind the sealing drive motor seat, and two or four rack limit seats are symmetrically installed in front of the sealing drive motor seat, a first rack that can slide therein is provided in the rack limit seat on the left, and a second rack that can slide therein is provided in the rack limit seat on the right, and the first rack and the second rack are positioned in parallel, a gear is installed on the output shaft of the sealing drive motor, the gear is located between the first rack and the second rack and meshes with the first rack and the second rack, a connecting seat is installed on the upper end of the first rack, an upper sealing assembly is installed below the connecting seat, and the second rack A lower sealing assembly is installed at the upper end, a left induction sheet is installed on the first rack, a right induction sheet is installed on the second rack, a left photoelectric switch is installed on the left side of the sealing drive motor seat, and a right photoelectric switch is installed on the right side. When the gear rotates counterclockwise, the upper sealing assembly and the lower sealing assembly move relative to each other along the same axis and can reach the upper and lower end surfaces of the reaction cup position at the same time to achieve sealing of the two ends of the reaction cup position. When the reaction cup position is in a sealed state, the right induction sheet is located in the induction area of ​​the right photoelectric switch. When the upper sealing assembly and the lower sealing assembly leave the reaction cup position and the upper sealing assembly reaches the upper limit position, the left induction sheet is located in the induction area of ​​the left photoelectric switch.

4. A chemiluminescence interpretation device applied to a turntable platform according to claim 2 or 3, characterized in that: The upper sealing assembly includes an upper guide base, an upper sealing guide sleeve is installed on the upper guide base, a first spring is arranged in the upper sealing guide sleeve, a sealing cover is installed in the front end of the upper sealing guide sleeve, the upper end of the sealing cover has a certain sliding space in the sealing guide sleeve, and the two ends of the first spring are respectively in contact with the upper guide base and the top of the sealing cover.

5. The chemiluminescence interpretation device applied to a turntable platform according to claim 3, characterized in that: The lower sealing assembly includes a lower guide base, a lower sealing guide sleeve is installed on the lower guide base, a second spring is arranged in the lower sealing guide sleeve, a sealing bracket is installed on the lower sealing guide sleeve, a sealing gasket is arranged on the sealing bracket, the sealing gasket is fixed to the sealing bracket by bonding, the lower end of the sealing bracket has a certain sliding space in the lower sealing guide sleeve, and the two ends of the second spring are respectively in contact with the lower guide base and the bottom of the sealing bracket.

6. A chemiluminescence interpretation device applied to a turntable platform according to claim 1, 2 or 3, characterized in that: The upper end of the first rack is an optical axis, a bushing is installed on the optical axis, the outer ring of the bushing is fixed on the connecting block, and the other end of the connecting block is fixed on the reading bracket.

Citation Information

Patent Citations

  • Fully automatic biochemical and luminescent immunoassay system

    CN104297498A

  • Enzyme-labeling measuring instrument detecting box body

    CN202159063U

  • Chemiluminiscence tester

    CN205991944U

  • Reaction cup is reading device in succession

    CN207866834U

  • Read mean is declared in automation of chemiluminescent immunoassay analysis appearance

    CN207866840U