Special feeding box for experimental mice

By designing a closed experimental rat feeding box, combined with an automated feeding, cleaning and weighing system, the problems of disturbance and data accuracy during the feeding process of experimental rats in the prior art are solved, and more efficient and accurate experimental data collection is achieved.

CN110731274BActive Publication Date: 2025-04-18JILIN AGRI SCI & TECH COLLEGE
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Patent Information

Application Number
CN201911118493.8
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2019-11-15
Publication Date
2025-04-18
Estimated Expiration
2039-11-15

AI Technical Summary

Technical Problem

The existing experimental mouse breeding device can easily disturb the experimental mice during feeding, cleaning and weighing, causing them to be in a stressed state and affect the experimental results. Frequent weighing and observation will increase interference to the experimental mice and reduce the accuracy of the data.

Method used

A special feeding box for experimental mice was designed. The box is surrounded by multiple plate structures to provide a closed living environment. It is equipped with an automated feeding, cleaning and weighing system, including a drinking water tank, a food tank, a funnel feces tank, a weighing sensor and a wide-angle camera, and automated control and data recording are achieved through an industrial control machine.

Benefits of technology

The device can feed, clean and weigh without disturbing the experimental mice, reduce interference to the experimental mice, improve the accuracy and reliability of the experimental results, and improve data acquisition efficiency through an automated system.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a special feeding box for laboratory mice, which is used for feeding and observing laboratory mice. The box body is composed of a top plate, a bottom plate, a front lower vertical plate, a front upper inclined plate, a rear vertical plate, a left vertical plate and a right vertical plate. The front upper inclined plate is a box cover, a food trough and a water tank are arranged on the front lower vertical plate, the front part of the bottom plate is a panel, and the rear part is a fence. A weighing sensor with a weighing platform is arranged on the panel. The rear end of the weighing platform is close to the fence. The weighing sensor communicates with an industrial computer to record the weight of the laboratory mice. The fully surrounded box body is more in line with the habit of the laboratory mice to avoid light, and non-interference feeding is achieved through the food trough and the water tank. Since the laboratory mice are accustomed to defecate away from the food feeding area and the rest area, the laboratory mice will defecate at the fence at the rear of the bottom plate, and the excrement will fall outside the box through the fence. The excrement is cleaned outside the box to achieve non-interference cleaning. The feeding box can provide a suitable living environment for the laboratory mice, and the feeding, cleaning and weighing processes will not disturb the laboratory mice.
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Description

Technical Field

[0001] The invention relates to an animal experiment device, in particular to a special feeding box for experimental mice. Background Art

[0002] Feeding laboratory mice is an important part of animal experiments, and the living environment of laboratory mice often interferes with the experimental results. At present, there is no scientific and unified laboratory mouse feeding device. Most laboratory mice are fed in boxes, troughs, cages and other equipment equipped with drinking water bottles. When using them, bedding is placed on the bottom of the box, and corresponding water and food are provided regularly to meet the growth needs of laboratory mice. However, laboratory mice are naturally timid and afraid of light and disturbance. During daily feeding and cleaning, the lids are often opened to allow natural light to disturb the laboratory mice, causing the laboratory mice to be in a state of stress for a long time. The psychological and physiological interference will eventually affect the experimental results and reduce the experimental effect. In addition, in the experiment, the laboratory mice must be weighed and observed regularly as needed. During the weighing process, the laboratory mice need to be captured and put on the weighing device. Whether capturing or observing the laboratory mice, the laboratory mice generally show fear and resistance, so the only way is to minimize the number of observations and weighing times to reduce interference with the laboratory mice. The disadvantage is that the data information obtained is suddenly reduced, which is not conducive to the experiment, and increasing the number of weighing and observation times will frequently stimulate the laboratory mice, resulting in the experimental results being affected. The contradiction between the above problems is the technical bottleneck and technical difficulty in the existing laboratory mouse breeding process. Summary of the invention

[0003] The purpose of the present invention is to solve the above-mentioned technical bottlenecks and technical difficulties and provide a special feeding box for experimental mice, which can provide the experimental mice with a suitable living environment and the feeding, cleaning and weighing processes will not disturb the experimental mice.

[0004] The technical solution of the present invention is: a special feeding box for experimental mice, which has a box body, characterized in that: the box body is composed of a top plate, a bottom plate, a front lower vertical plate, a front upper inclined plate, a rear vertical plate, a left vertical plate, and a right vertical plate, wherein the upper end of the front upper inclined plate is hinged to the front end of the top plate, the lower end of the front upper inclined plate is movably pressed with the upper end of the front lower vertical plate, and the left and right ends of the front upper inclined plate are movably pressed with the corresponding end surfaces of the left and right vertical plates; a food trough mounting hole and a drinking water tank mounting hole are provided on the front lower vertical plate, the drinking water tank mounting hole is equipped with a drinking water tank, the tank body of the drinking water tank is connected to the front lower vertical plate, the water outlet of the drinking water tank is placed inside the box body, and the water filling port of the drinking water tank is placed outside the box body; the food trough mounting hole is equipped with a food trough, and the food trough is slidably connected to the food trough mounting hole front and back, and the food trough A trough handle and a front convex plate are fixedly connected at the front end, a rear end face of the front convex plate is movably pressed with the front end face of the front lower vertical plate, a rear end of the trough is provided with a rear convex plate, and a front end face of the rear end face of the rear lower vertical plate is movably pressed with the rear end face of the front lower vertical plate; the front part of the bottom plate is a panel and the rear part is a fence, a weighing sensor is mounted on the panel, a weighing platform is mounted on the weighing sensor, the rear end of the weighing platform is close to the fence, gaps are provided between the two ends of the weighing platform and the left and right vertical plates, the front end of the panel is fixedly connected to the front lower vertical plate, the rear end of the panel is fixedly connected to the front end of the fence, the rear end of the fence is fixedly connected to the rear vertical plate, and the left and right end faces of the fence and the panel are fixedly connected to the corresponding left and right vertical plates; an industrial computer is mounted on the box body, and a signal output terminal provided on the weighing sensor is communicatively connected with a signal input terminal provided on the industrial computer through a signal line.

[0005] A funnel is arranged below the fence, a wide opening above the funnel is opposite to the fence, a manure collecting trough is arranged below the funnel, and a notch of the manure collecting trough is opposite to a narrow opening below the funnel.

[0006] The front upper inclined plate is a one-way perspective plate.

[0007] The box has a wide-angle camera installed at the top corner inside, and a video signal output terminal provided on the camera is communicatively connected with a video signal input terminal provided on the industrial computer through a video line.

[0008] The top plate is provided with a rectangular hole, and a set of pulley groups are respectively installed on the top plates located at the left and right ends of the rectangular hole, and the two pulley groups are arranged in parallel. At least one pulley in each pulley group is a power pulley driven by a motor, and a lamp holder is installed between the two pulley groups. The two ends of the lamp holder are supported by the belts in the two pulley groups and are arranged on the rectangular hole for forward and backward displacement. The bottom surface of the lamp holder is provided with an LED lamp. When the lamp holder is located at the front stop point of the movement, the LED lamp is opposite to the rear end of the electronic scale, and when the lamp holder is located at the rear stop point of the movement, the LED lamp is opposite to the rear end of the fence; a front touch sensor is installed on the top plate located at the front end of the rectangular hole, and a rear touch sensor is installed on the top plate located at the rear end of the rectangular hole. The front end of the lamp holder is provided with a front touch sensor. A front limit plate corresponding to the contact in the touch sensor and a rear limit plate corresponding to the contact in the rear touch sensor are provided at the rear end of the lamp holder; a shading plate is covered above the rectangular hole, the shading plate is fixedly mounted on the top plate, and a gap is provided between the shading plate and the top plate; an infrared sensor is installed on the top plate or the front upper inclined plate, and the detection end of the infrared sensor is opposite to the weighing platform of the electronic scale; the electric input end provided on the LED lamp and the electric input end provided on each motor are electrically connected to the electric output end provided on the industrial computer through electric wires; the signal output end provided on the front touch sensor, the signal output end provided on the rear touch sensor, and the signal output end provided on the infrared sensor are communicatively connected to the signal input end of the industrial computer through signal lines.

[0009] A power source is arranged on the outer surface of the box body, and an electric output terminal of the power source is electrically connected with an electric input terminal of the industrial computer through electric wires.

[0010] The industrial computer is integrated with a wireless communication device, and the data transceiver provided on the wireless communication device is connected to the data transceiver provided on the industrial computer through a data line.

[0011] The water inlet of the drinking water tank is connected with a water supply hose through a manifold. One end of the water supply hose is a blind end, and the other end is connected to a water supply tower.

[0012] The advantages of the present invention are that the experimental mice are raised in the box, and the plate structures constituting the box body completely surround the experimental mice and isolate them from the external space. Compared with traditional open-type raising containers such as boxes, troughs and cages, the present invention is more in line with the habit of experimental mice to avoid light.

[0013] When feeding, food is added by pulling out the feeding trough. The water inlet of the drinking water tank is placed outside the box, so water can be added to the drinking water tank outside the box, thus achieving undisturbed feeding.

[0014] Since the experimental mice are used to defecating away from the food feeding area and rest area, the experimental mice will defecate at the fence at the rear of the bottom plate. The excrement falls outside the box through the fence and can be cleaned outside the box, thus achieving non-interference cleaning;

[0015] A weighing platform is set on the panel near one side of the fence. Every time the experimental mouse goes to defecate and passes through the weighing platform, the weighing sensor transmits the measured data to the industrial computer through the signal line, so as to automatically record the weight of the experimental mouse before and after defecation, and automatically weigh the experimental mouse according to the activity habits of the experimental mouse, thereby realizing interference-free weighing.

[0016] The funnel can collect the feces of the experimental mice into the feces collecting trough, and the feces of each experimental mouse can be tested individually, thereby further improving the accuracy of the test data.

[0017] The one-way perspective board and built-in wide-angle camera can observe the status of experimental mice in real time under undisturbed conditions, thereby increasing the amount of information collected and ensuring accurate test results.

[0018] Taking advantage of the light-avoiding habit of experimental mice, when the experimental mice are located at the fence, the LED light sweeping from the back to the front drives the experimental mice to pass through the weighing platform, thereby realizing the active measurement of the experimental mouse's weight. The infrared sensor can monitor whether the experimental mouse passes through the weighing platform. When the industrial control computer learns that the infrared sensor has not detected the experimental mouse, it drives the LED lamp frame to reciprocate once more through the driving pulley group, thereby ensuring that the experimental mouse's weight data can be obtained. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 A schematic perspective view of the right front structure of the special feeding box for experimental mice of the present invention.

[0020] Figure 2 The left front structural schematic diagram of the special feeding box for experimental mice of the present invention.

[0021] Figure 3 A schematic perspective view of the left rear structure of the special feeding box for experimental mice of the present invention.

[0022] Figure 4 The schematic diagram of the right rear structure of the special feeding box for experimental mice of the present invention.

[0023] Figure 5 A schematic front structural view of a special feeding box for experimental mice of the present invention.

[0024] Figure 6 Originally Figure 5 Schematic diagram of the cross-sectional structure along the AA direction.

[0025] Figure 7 Originally Figure 5 Schematic diagram of the cross-sectional structure along the BB direction.

[0026] Figure 8 Schematic diagram of the use of the special feeding box for experimental mice of the present invention Figure 1 .

[0027] Fig. 9 Schematic diagram of the use of the special feeding box for experimental mice of the present invention Figure 2 .

[0028] Fig.10 Structural block diagram of each electrical component in the present invention.

[0029] Fig.11 A schematic diagram of the command execution flow of a preset program in an industrial computer in the present invention.

[0030] In the figure, 1 is a front upper inclined plate, 2 is a hinge, 3 is a top plate, 4 is a belt, 5 is a power wheel, 6 is a motor, 7 is a support wheel, 8 is a front touch sensor, 9 is a left vertical plate, 10 is a lamp holder, 11 is an LED lamp, 12 is a pulley, 13 is a shading plate, 14 is a wheel holder, 15 is a wide-angle camera, 16 is a front limit plate, 17 is a rear limit plate, 18 is a rear touch sensor, 19 is a middle contact point of the rear touch sensor, 20 is a rectangular hole, 21 is a rear vertical plate, 22 is a right vertical plate, 23 is a fence, 24 is a handle, 25 is a narrow opening below the funnel, 26 is a funnel, 27 is a wide opening above the funnel, 28 is a foot, 29 is a hook, 30 is a brush, 31 is a weighing sensor sensor, 32 weighing platform, 33 panel, 34 drinking water tank installation hole, 35 front lower vertical plate, 36 drinking water tank, 37 trough installation hole, 38 trough, 39 trough handle, 40 front convex plate, 41 rear convex plate, 42 switch button, 43 hand pull, 44 infrared sensor, 45 industrial computer, 46 wireless communication device, 47 power supply, 48 pulley group, 49 USB interface, 50 battery compartment, 51 front touch sensor middle contact, 52 drinking water tank water filling port, 53 drinking water tank water outlet, 54 handle, 55 manure trough, 56 support rod, 57 water supply tower, 58 water supply hose, 59 manifold. DETAILED DESCRIPTION

[0031] A special feeding box for experimental mice comprises a box body, wherein the box body is formed by a top plate 3, a bottom plate, a front lower vertical plate 35, a front upper inclined plate 1, a rear vertical plate 21, a left vertical plate 9, and a right vertical plate 22, wherein the upper end of the front upper inclined plate is hinged to the front end of the top plate, the lower end of the front upper inclined plate is movably pressed into contact with the upper end of the front lower vertical plate, and the left and right ends of the front upper inclined plate are movably pressed into contact with the corresponding end faces of the left and right vertical plates; a food trough mounting hole 37 and a drinking water tank mounting hole 34 are provided on the front lower vertical plate, a drinking water tank 36 is installed in the drinking water tank mounting hole, the tank body of the drinking water tank is connected to the front lower vertical plate, the water outlet 53 of the drinking water tank is placed inside the box body, and the water filling port 52 of the drinking water tank is placed outside the box body; the food trough mounting hole is provided with a food trough 38, the food trough is slidably connected to the food trough mounting hole front and back, and the front end of the food trough is fixedly connected with A trough handle 39 and a front convex plate 40, the rear end face of the front convex plate is movably pressed with the front end face of the front lower vertical plate, and a rear convex plate 41 is provided at the rear end of the trough, and the front end face of the rear convex plate is movably pressed with the rear end face of the front lower vertical plate; the front part of the bottom plate is a panel 33, and the rear part is a fence 23, a weighing sensor 31 is mounted on the panel, a weighing platform 32 is mounted on the weighing sensor, the rear end of the weighing platform is close to the fence, and gaps are provided between the two ends of the weighing platform and the left and right vertical plates, the front end of the panel is fixedly connected to the front lower vertical plate, the rear end of the panel is fixedly connected to the front end of the fence, the rear end of the fence is fixedly connected to the rear vertical plate, and the left and right end faces of the fence and the panel are fixedly connected to the corresponding left and right vertical plates; an industrial computer 45 is mounted on the box body, and a signal output terminal provided on the weighing sensor is communicatively connected with a signal input terminal provided on the industrial computer through a signal line.

[0032] A funnel 26 is provided below the fence, and a wide opening 27 above the funnel is opposite to the fence. A manure collecting trough 55 is provided below the funnel, and the notch of the manure collecting trough is opposite to the narrow opening 25 below the funnel.

[0033] The front upper inclined plate is a one-way perspective plate.

[0034] The box has a wide-angle camera 15 installed at the top corner inside, and a video signal output terminal provided on the camera is connected to a video signal input terminal provided on the industrial computer through a video line.

[0035] The top plate is provided with a rectangular hole 20, and a set of pulley groups 48 are respectively installed on the top plates at the left and right ends of the rectangular hole. The two pulley groups are arranged in parallel, and at least one of the pulleys 12 in each pulley group is a power wheel 5 driven by a motor 6. A lamp holder 10 is installed between the two pulley groups. The two ends of the lamp holder are supported by the belts 4 in the two pulley groups and are mounted on the rectangular hole for forward and backward displacement. The bottom surface of the lamp holder is provided with an LED lamp 11. When the lamp holder is located at the front stop point of the movement, the LED lamp is opposite to the rear end of the electronic scale, and when the lamp holder is located at the rear stop point of the movement, the LED lamp is opposite to the rear end of the fence; a front touch sensor 8 is installed on the top plate at the front end of the rectangular hole, and a rear touch sensor 18 is installed on the top plate at the rear end of the rectangular hole. The front end of the lamp holder is provided with a front touch sensor 18. A front limit plate 16 corresponding to the contact 51 in the front touch sensor, and a rear limit plate 17 corresponding to the contact 19 in the rear touch sensor are provided at the rear end of the lamp holder; a shading plate 13 is covered above the rectangular hole, and the shading plate is fixedly mounted on the top plate, and a gap is provided between the shading plate and the top plate; an infrared sensor 44 is installed on the top plate or the front upper inclined plate, and the detection end of the infrared sensor is opposite to the weighing platform of the electronic scale; the electric input end provided on the LED lamp and the electric input end provided on each motor are electrically connected to the electric output end provided on the industrial computer through electric wires; the signal output end provided on the front touch sensor, the signal output end provided on the rear touch sensor, and the signal output end provided on the infrared sensor are each communicatively connected to the signal input end of the industrial computer through a signal line.

[0036] A power supply 47 is mounted on the outer surface of the box, and an electrical output terminal of the power supply is electrically connected to an electrical input terminal of the industrial computer through an electric wire.

[0037] The industrial computer is integrated with a wireless communication device 46, and the data transceiver provided on the wireless communication device is connected to the data transceiver provided on the industrial computer through a data line.

[0038] The water inlet of the water tank is connected to a water supply hose 58 through a manifold 59 , one end of the water supply hose is a blind end, and the other end is connected to a water supply tower 57 .

[0039] Since the experimental mice are afraid of light, for the purpose of the invention, the top plate, bottom plate, front lower vertical plate, rear vertical plate, left vertical plate and right vertical plate that constitute the box body are all opaque plates, and the corresponding edges between the plates are fixedly connected together by conventional methods, such as gluing, welding, screw assembly, etc. In order to facilitate transportation, handles 24 are also installed on the outer facades of the left and right vertical plates. The front upper inclined plate is set to be tilted backward at its upper end. One of the purposes of the tilt is to maintain its normally closed state by the principle of gravity. The front upper inclined plate is hinged to the top plate through a hinge 2. Usually, the height of the front lower vertical plate is higher than the height at which the experimental mice can stand upright and climb. However, if necessary, a locking mechanism of conventional structure can be installed between the front upper inclined plate and the front lower vertical plate, the top plate, the left vertical plate or the right vertical plate to prevent the experimental mice from pushing the front upper inclined plate away and escaping. The front upper inclined plate is also provided with a hand poke 43 for lifting the front upper inclined plate. The openable front upper inclined plate actually constitutes the box cover of the box body. The upper front inclined plate is arranged to be tilted backward at its upper end. The second purpose of the tilt is to facilitate observation of the experimental mice from outside the box. The upper front inclined plate is a one-way perspective plate structure, which can be used to observe the living conditions of the experimental mice from the outside without disturbing the experimental mice. Therefore, the upper front inclined plate is an opaque plate or a one-way perspective plate. The one-way perspective plate is a one-way perspective glass plate, a one-way perspective plastic plate or a transparent plate with a one-way perspective film material.

[0040] Conventionally, the bottom of the box is provided with legs 28 for supporting the box, so that a gap is left between the bottom of the box and the table on which the box is placed, which is for ventilation on one hand and for easy collection and cleaning of the excrement of the experimental mice on the other hand. A hook 29 is provided on the facade of the outer surface of the box, and a brush 30 is hung on the hook. The brush can be used to clean the inside of the box. The brushes are arranged one by one on the box to avoid cross infection of experimental mice in different boxes, so that the test data is more objective and accurate.

[0041] The drinking water tank is a special drinking water tank for rodents and is a commercially available product. It includes a small water storage tank. A metal drinking water pipe extending downward at 30 degrees is extended from the lower part of the water storage tank. The inlet of the drinking water pipe is connected to the inside of the water storage tank. A half-wrapped arc-shaped opening is provided on the outlet edge of the drinking water pipe. A movable steel ball is installed in the arc-shaped opening. The experimental mouse pushes the steel ball with its tongue to create a gap between the steel ball and the arc-shaped opening, so that the mouse can drink the water in the drinking water pipe. The arc-shaped opening is the water outlet of the drinking water tank. The water filling port of the drinking water tank is usually arranged at the upper part of the water storage tank, which is used to add water to the water storage tank.

[0042] The trough has a width dimension greater than the thickness of the front lower upright plate. In the structure in which the trough is slidably connected to the trough mounting hole front and rear, the trough is pulled outward until the rear convex plate at the rear end of the trough contacts the front lower upright plate for a limit position, and the notch of the trough is exposed to the outside of the box body, and mouse food can be added to the trough. Then, the trough is pushed into the box until the rear front convex plate at the front end of the trough contacts the front lower upright plate for a limit position, and the notch of the trough is exposed to the inside of the box body for experimental mice to take food. A padlock or a conventional limiting mechanism can be installed between the trough and the front lower upright plate to limit the working position of the trough.

[0043] The front end of the panel of the bottom plate is connected to the lower end of the front lower vertical plate, the left and right ends of the panel are connected to the corresponding left and right vertical plates, and the left and right ends of the fence are connected to the corresponding left and right vertical plates. The fence is composed of a plurality of corrosion-resistant metal rods arranged at intervals in front and back, and the gaps between the metal rods are set to allow the spherical feces of the experimental mice to pass through but not allow the experimental mice to escape. In addition, the grille can also play a role in air circulation inside and outside the box.

[0044] A gap is provided between the shading plate and the top plate, which can also facilitate air circulation inside and outside the box.

[0045] The funnel is preferably made of stainless steel, and a hydrophobic coating is provided on the inner surface of the funnel. A handle 54 is fixedly connected to the manure collecting trough, and the manure collecting trough can be taken out from the bottom of the box body by the handle.

[0046] The sunshade is fixedly connected to the top plate via four support rods 56, wherein the upper end of each support rod is fixedly connected to the sunshade, and the lower end of each support rod is fixedly connected to the top plate.

[0047] The weighing sensor and the weighing platform constitute an electronic scale, which is a commercially available product. The weighing sensor supports the weighing platform on the panel of the bottom plate. When the experimental mouse is located above the weighing platform, the experimental mouse can be weighed. Usually, the front and rear widths of the weighing platform are greater than the stride length of the experimental mouse's limbs, so that when the experimental mouse is located or passes through the weighing platform, its limbs are simultaneously located above the weighing platform, ensuring accurate weighing. The weighing sensor has an independent battery or uses power supply from an industrial computer. In conventional technology, the weighing sensor has a display screen, which is used to display the weighed weight for easy observation by human eyes. The display screen can be set on the outer surface of the box body where it is easy to observe, or the weighing sensor sends the obtained weight signal to the industrial computer, which records and displays it.

[0048] The infrared sensor is a product of the prior art. It is a sensor that can sense infrared radiation from a target and use the physical properties of infrared rays to perform measurements. Since laboratory mice are warm-blooded animals with a body surface temperature higher than room temperature, in this application, the infrared sensor corresponding to the weighing platform can sense whether the laboratory mouse is on the weighing platform or whether the laboratory mouse passes through the weighing platform through the body temperature of the laboratory mouse.

[0049] The pulley group includes a belt and at least two pulleys, wherein the pulleys include at least a driving wheel and a driven wheel, the driving wheel and the driven wheel are respectively located at both ends of the belt to play the role of tensioning support and driving the belt to rotate around the two wheels, and a plurality of supporting wheels 7 can be provided between the driving wheel and the driven wheel, each wheel is fixed to the top surface of the top plate through a wheel frame 14, and the supporting wheels are used to support the belt between the driving wheel and the driven wheel to make the belt section located above straight.

[0050] The motor may be a stepper motor, the controller of the stepper motor is integrated in the industrial computer, and the driven wheel may also be equipped with a stepper motor for precise control.

[0051] The touch sensor is a commercially available product. The contact point of the touch sensor generally refers to a contact head, a switch, an electrode, etc. provided on the touch sensor and used to trigger the touch sensor to send a signal.

[0052] The LED is a commercially available lamp, which has strong light and saves electricity. In this application, variable light intensity LED is used, and its light intensity is controlled by an industrial computer according to the voltage. The lamp holder is controlled by an industrial computer, and the light is used to drive the experimental mice to pass through the weighing platform by taking advantage of the light avoidance of mice to complete the weighing.

[0053] The industrial computer is also called a controller, a programmable controller, a numerical control storage device or a microcomputer. It is a prior art product. It includes a circuit board and a computing module, a storage module, a clock module, a signal input terminal, a signal sending terminal, a communication module, a human-computer interaction module, a power supply module, etc. installed on the circuit board and working in coordination. A pre-written program is stored in the storage unit. The signal input terminal sends the received various signal data to the computing module for processing. After the program logic operation, the computing unit transmits various instructions to the lower computer through the signal sending terminal. This is a working cycle. The industrial computer is provided with a switch button 42, through which various instructions are issued to the industrial computer. The human-computer interaction module includes a touch display screen, a USB interface 49, etc. The USB interface can be connected to auxiliary electronic devices such as a keyboard, a mouse, and a mobile storage device. The power source is a battery or a battery compartment 50. The battery is connected to the industrial computer and various electrical components through wires. The electrical output terminal of the battery compartment is connected to the electrical input terminal provided on the industrial computer through wires. The battery of a specified model and specification can be inserted into the battery compartment to power various electrical components. In the present application, the industrial computer is mainly responsible for receiving signals from various sensors, and controlling the start and stop status of the motor, LED light, and wide-angle camera according to the logic of the signals. The industrial computer also has a basic storage function, which is used to store the data transmitted by the weighing sensor and the wide-angle camera, and use a wireless communication device to send the above data to a remote lower computer. The lower computer includes a computer or a mobile phone. The industrial computer can also receive command data from the lower computer through a wireless communication device, and execute relevant instructions according to the content of the command data, such as: retrieving stored or online video content, retrieving weighing information, starting an active weighing program, upgrading internal programs, starting a self-test program, etc.

[0054] The wide-angle camera can capture the overall situation inside the box. The camera is preferably a night vision camera, which is tilted downward, so that the activity status of the experimental mice in the box can be recorded to the maximum extent. With the development of technology in this application, the camera can use AI to identify each experimental mouse, so that the industrial computer can establish a growth information library for each experimental mouse, that is, record its daily eating times, drinking times, activity status, stress and its weight each time it is weighed, and record it in the form of data in the industrial computer, and transmit it to the experimenter's mobile client in a timely manner through 5G; at the same time, it can identify abnormal states of mice, such as convulsions, death, etc., which can only be identified through AI and alarmed through the industrial computer and wireless communication device.

[0055] The water supply tower should be placed higher than the water tank, and gravity is used to supply water to the water tank. The water supply tower can be connected to multiple water tanks at the same time, and the water capacity of the water supply tower can be limited according to actual needs. Setting up a water tower can reduce the number of water replenishment times and reduce the workload of feeding experimental mice.

[0056] The switch button on the industrial computer is set with two modes: long press and short press. When you only need to observe the condition of the mouse, press the switch button, and the controller starts the wide-angle camera. At this time, the industrial computer can record or send the screen inside the box in real time. After the corresponding time, the industrial computer is turned off, the power supply is kept, and the command ends. When weighing is required, press the switch button for more than 3 seconds, and the industrial computer activates the front and rear touch sensors. If the controller receives the collision signal of the rear touch sensor, the weighing sensor and the infrared sensor are activated. The weighing sensor begins to sense whether there is an experimental mouse pressing, and the infrared sensor starts to sense whether there is an experimental mouse passing above the weighing platform; if the controller does not receive the collision signal of the rear touch sensor, the industrial computer supplies power to the motor to drive the lamp holder to move slowly from front to back until the controller receives the collision signal of the rear touch sensor. The purpose is to ensure that the lamp holder is located at the rear end of the box, so that the next instruction can be started. In the next instruction, if the industrial computer receives the gravity signal from the weighing sensor and the infrared sensor also detects the presence signal of the experimental mouse, the industrial computer sends a command to the front touch sensor, and the front touch sensor starts; otherwise, the industrial computer turns on the LED, etc., and supplies power to the motor, driving the light rack to move slowly from back to front, and gradually increases the LED light intensity. The light rack continues to move forward until the weighing sensor and the infrared sensor transmit signals to the industrial computer, and stops, waiting for the next instruction. Since mice are light-averse, the experimental mouse cage is in a dark environment as a whole. The LED light is strong and moves from back to front, thereby driving the mice to the weighing platform. In the next instruction, the industrial computer receives the weight signal sent by the weighing sensor and stores it for display output or uploads the weight signal to the specified lower computer for collection, and the weighing process ends; LED light can also form a light wall to restrict the experimental mice to move on the panel equipped with the weighing platform, so that weighing can also be completed.

[0057] The camera used in the specific implementation of this application is a backlight wide dynamic micro USB camera, which is a camera model CC56702300130_3828_V1.0 produced by Shenzhen Sanxin Microelectronics Co., Ltd.; the infrared sensor used is an infrared sensor model AS312 sold by Zhongganxin Electronics Store in Luohu District, Shenzhen; the touch sensor uses a long-handled small micro switch, which is a WK1-04 touch switch commercially available from Dongguan Hezhi Electronics Co., Ltd.; the motor uses a 42 series Shinano stepper motor, which is a motor model SST43D2120 produced and sold by Dongguan Hongai Automation Technology Co., Ltd.; the weighing sensor uses a CZL928 micro weighing force sensor, which is a weighing sensor model CZL928 produced and sold by Guangdong Hualanhai Electric Measurement Technology Co., Ltd.; the industrial computer uses an Arduino uno R3 type uno r3 controller sold by Shenzhen Futian District Zhichuang Microelectronics Store, and the battery uses a model 602535 3.7V 500mah polymer lithium battery, produced and sold by Shenzhen Pramax Technology Co., Ltd.

Claims

1. A special feeding box for experimental mice, comprising a box body, characterized in that: The box body is composed of a top plate, a bottom plate, a front lower vertical plate, a front upper inclined plate, a rear vertical plate, a left vertical plate and a right vertical plate, wherein the upper end of the front upper inclined plate is hinged to the front end of the top plate, the lower end of the front upper inclined plate is movably pressed into the upper end of the front lower vertical plate, and the left and right ends of the front upper inclined plate are movably pressed into the corresponding end faces of the left and right vertical plates; a food trough mounting hole and a water tank mounting hole are provided on the front lower vertical plate, the water tank mounting hole is equipped with a water tank, the tank body of the water tank is connected to the front lower vertical plate, the water outlet of the water tank is placed inside the box body, and the water filling port of the water tank is placed outside the box body; a food trough mounting hole is equipped with a food trough, the food trough is slidably connected to the food trough mounting hole front and back, the front end of the food trough is fixedly connected with a food trough handle and a front convex plate, the rear end face of the front convex plate is movably pressed into the front end face of the front lower vertical plate, the rear end of the food trough is provided with a rear convex plate, the front end face of the rear convex plate is The rear end surface of the vertical plate is movably crimped; the front part of the bottom plate is a panel and the rear part is a fence. A weighing sensor is installed on the panel, and a weighing platform is provided on the weighing sensor. The rear end of the weighing platform is close to the fence, and gaps are provided between the two ends of the weighing platform and the left and right vertical plates. The front end of the panel is fixedly connected to the front lower vertical plate, the rear end of the panel is fixedly connected to the front end of the fence, the rear end of the fence is fixedly connected to the rear vertical plate, and the left and right end surfaces of the fence and the panel are fixedly connected to the corresponding left and right vertical plates; an industrial computer is installed on the box body, and a signal output terminal provided on the weighing sensor is communicatively connected with a signal input terminal provided on the industrial computer through a signal line; the front upper inclined plate is a one-way perspective plate; a front touch sensor and a rear touch sensor are installed on the top plate, and a shading plate is fixedly installed on the top plate. An infrared sensor is installed on the top plate or the front upper inclined plate, and the detection end of the infrared sensor is opposite to the weighing platform of the electronic scale.

2. The special feeding box for experimental mice according to claim 1, characterized in that: A funnel is arranged below the fence, a wide opening above the funnel is opposite to the fence, a manure collecting trough is arranged below the funnel, and a notch of the manure collecting trough is opposite to a narrow opening below the funnel.

3. The special feeding box for experimental mice according to claim 1, characterized in that: The box has a wide-angle camera installed at the top corner inside, and a video signal output terminal provided on the camera is communicatively connected with a video signal input terminal provided on the industrial computer through a video line.

4. The special feeding box for experimental mice according to claim 1, characterized in that: A power source is arranged on the outer surface of the box body, and an electric output terminal of the power source is electrically connected with an electric input terminal of the industrial control computer through electric wires.

5. The special feeding box for experimental mice according to claim 1, characterized in that: A wireless communication device is integrated on the industrial computer, and a data transceiver provided on the wireless communication device is connected to a data transceiver provided on the industrial computer through a data line.

6. The special feeding box for experimental mice according to claim 1, characterized in that: The water filling port of the drinking water tank is connected to a water supply hose through a manifold. One end of the water supply hose is a blind end, and the other end is connected to a water supply tower.

Citation Information

Patent Citations

  • Radiobiological functional experiment box

    CN104126516A

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    CN105486813A

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    CN108967218A

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    CN211153236U