Flow test unit, kit and use of flow test unit for performing a detection reaction

Abstract

The invention relates to a flow test unit (1), comprising a housing (2) which is sealed to the outside at least in the connection position with a sample container, at least one test strip (3) being enclosed in the housing, the housing (2) having at least one input opening (4), and the test strip (3) being arranged in the housing (2) in such a way that after a liquid connection (22) with the sample container is established, a wetting area (5) can be wetted by a liquid (6) entering via the at least one input opening (4).

Description

Technical Field

[0001] The invention relates to a flow test unit, a kit comprising the flow test unit and a sample container, and an application of the flow test unit for performing a detection reaction. Background Art

[0002] Lateral flow tests (also called lateral flow tests) are known and are biochemical methods for the qualitative detection of substances using specific antibodies against these substances.

[0003] Lateral flow tests are often used as detection methods, since the equipment expenditure required for this is very low. It is known that lateral flow tests can be performed using test strips. The structure of such test strips is therefore also known from the prior art.

[0004] The use of test strips is usually not very complicated. However, if test strips are to be used to check infectious and / or health-hazardous materials for the presence of specific substances, in particular proteins, the detection reaction with the aid of the test strips must be carried out by specially trained personnel in laboratories with a certain degree of protection. Otherwise, there is a risk of contamination of the environment and possible danger to nearby people.

[0005] Since it is often desirable to obtain the result of the test reaction as directly as possible in some tests, the known test strips are not suitable for carrying out the test reaction directly at the sampling location. Here, the sample must first be collected and transported to a laboratory suitable for carrying out the test reaction. As a result, it is usually necessary to take a long time before the result of the test reaction is available.

[0006] Therefore, it is particularly desirable to be able to carry out such a detection reaction in a closed system, preferably directly at the sampling site, without risk of contamination. Therefore, it is particularly desirable to be able to carry out the detection reaction in a closed system, in particular a hermetically sealed system, from which no potentially health-damaging sample material can reach the outside. Summary of the invention

[0007] The object is therefore to provide an improved possibility for carrying out detection reactions.

[0008] According to the invention, this object is achieved by a flow test cell having:

[0009] a housing closed to the outside, said housing comprising at least one test strip,

[0010] at least one input port in the housing, whereby the housing is closed except for the at least one input port,

[0011] The at least one test strip is arranged in the housing such that a wetting area of ​​the at least one test strip can be wetted by a liquid entering via the at least one inlet opening,

[0012] The housing has an impact protection device in the interior, by which the interior of the housing is divided into two chambers, the impact protection device separating the wetting area from the analysis area of ​​the at least one test strip, wherein the at least one test strip is positioned in a groove or cutout in the impact protection device and extends through the groove or cutout to prevent the at least one test strip from being pinched,

[0013] The housing has an outer side, on which a coupling site is arranged, and the flow test unit is arranged to be connected to a mating coupling site of a wall of the sample container via the coupling site, and

[0014] The housing also has a pressure equalization device to facilitate the inflow of liquid.

[0015] In order to achieve the stated object, a flow test unit is proposed, in particular, which has a housing closed to the outside, in which at least one test strip is located, in particular encapsulated, the housing having at least one input opening or exactly one input opening, the test strip being arranged in the housing in such a way that the wetted area can be wetted by the liquid entering via the at least one input opening. Thus, the test reaction can be carried out in a closed system with the help of the flow test unit, so that the risk of contamination of the environment is minimized. The test strip can be encapsulated preferably liquid-tightly or gas-tightly by the housing. A system that is liquid-tightly closed to the outside can be established by the housing at least in the connection area to the sample container.

[0016] Test strips are known from the prior art. Test strips are known which are formed by at least one fluidized layer on a carrier. The fluidized layer may, for example, have reactive and / or interactive ligands, such as antibodies, for the substance to be detected, through which a detection reaction can be carried out.

[0017] Advantageous embodiments of the present invention are described below.

[0018] In order to be able to connect the flow test unit to a container containing a sample to be analyzed, the housing can have a connection point on the outside, via which the flow test unit can be connected to a matching matching connection point of, for example, a wall of a sample container. In this way, a fixed, in particular irreversible connection to the other container can be established.

[0019] According to an advantageous embodiment, the at least one test strip can be divided into a wetting area and an analysis area. When the wetting area comes into contact with the liquid to be analyzed, a detection reaction can be initiated. The test strip can be configured, for example, for carrying out a lateral flow test. Thus, the presence of a specific substance in a specific sample can be analyzed relatively quickly. It can be particularly advantageous here that the analysis can be carried out at the sampling site by means of a flow test unit. In addition, the sample can be kept at any time in a space that is closed relative to the environment, which space can be connected to the interior of the flow test unit, so that a system that is closed relative to the environment exists.

[0020] According to another advantageous embodiment, the housing can have a pressure equalization device. The pressure equalization device can be designed here, for example, as a pressure relief opening and / or a collecting bag. Alternatively or in addition thereto, the pressure equalization device can be designed by providing the housing with a negative pressure. This has the advantage that, in particular, once the flow test unit is connected to the sample container, the flow of liquid into the housing can be promoted.

[0021] In order to be able to manufacture the flow test unit as simply and cost-effectively as possible, it can be provided according to an embodiment that the housing is designed in at least two parts or exactly in two parts. This allows industrial mass production. For example, the housing can consist of at least two housing parts, in particular designed as shells. The test strip can be inserted between the at least two housing parts.

[0022] According to another advantageous embodiment, it can be provided that the at least one test strip is held and / or laterally fixed by at least one retaining tab of the housing. Preferably, it can be held and / or fixed in such a way that the at least one test strip is in contact with the at least one retaining tab. Alternatively or in addition to this, the test strip can be held by the retaining tab in such a way that the test strip is not deformed by the at least one retaining tab. Therefore, it can be ensured that the liquid flows through the test strip unimpeded, thereby not affecting the test result. A plurality of retaining tabs can be constructed on the housing. The test strip can be arranged between one or more pairs of retaining tabs and / or between the inner wall of the housing and at least one retaining tab, respectively.

[0023] In order to prevent a surge-like inflow after the flow test unit is connected to a sample container, for example, which is triggered in particular by a pressure balance between the sample holding space of the sample container and the interior of the housing of the flow test unit, the housing may have an impact protection device inside, by which the housing is divided into two chambers. When a liquid connection is established between the flow test unit and the sample container by connecting the two, liquid flows from the sample container into the flow test unit. Here, the liquid may wet the following area of ​​the test strip, which itself is not provided for direct immersion in the liquid when the detection reaction is correctly carried out with the help of the test strip. Therefore, the surge-like inflow of liquid and the incorrect wetting of the test strip associated therewith may lead to inaccurate test results. It is therefore particularly advantageous that the wetting area of ​​the at least one test strip is arranged in the inflow chamber of the housing and the analysis area of ​​the at least one test strip is arranged in the analysis chamber of the housing. It can therefore be ensured that only the wetting area of ​​the test strip is in contact with the liquid, because the liquid level inside the housing is lower than the impact protection device after the pressure balance occurs. The impact protection device can be formed, for example, by the housing retaining tab described herein.

[0024] In order to be able to read the analysis result without having to open the housing of the flow test unit, the housing can be designed to be at least partially transparent. For example, the housing can have at least one transparent viewing window through which the result, such as a color reaction, can be read. Alternatively or in addition to this, the housing can have a marking, in particular on the outside, through which the user can read the analysis result. The marking can be, for example, a scale and / or at least one color reference value. As a result, the analysis performed by means of the flow test unit can be evaluated particularly easily, in particular without further equipment and / or references, such as for comparison with a color reaction, to determine the result.

[0025] In order to be able to establish a liquid connection with another container, such as a sample container, the at least one input opening can be designed as a penetration element. In particular, the input opening can be designed as a radially and / or axially protruding nose. With the help of the penetration element, for example, a predetermined breaking point in the wall of the sample container can be penetrated by the connection process of the flow test unit to the wall. This can be done so that a liquid connection with the sample container can be established via the input opening.

[0026] According to another advantageous embodiment, a pressure equalization device, such as the pressure equalization device already mentioned above, such as in particular a pressure relief opening, can have a blocking element. The blocking element can be designed, for example, as a filter. The blocking element can prevent the liquid from flowing out of the housing interior. Thus, after the flow test unit is connected to a further container, a closed system can be formed, in which the same pressure as the ambient pressure preferably prevails. However, at least the pressure inside the container, in particular the pressure inside the sample receiving space of the container, and the interior of the housing of the flow test unit, in particular the chamber, is pressure-equalized.

[0027] The present invention also relates to a kit, comprising a flow test unit as described and claimed herein and a sample container, the sample container having a mating connection portion that matches the connection portion of the flow test unit. Thus, a consistent sample container can be configured to be combined with a plurality of different flow test units and / or a consistent flow test unit can be configured to be combined with different sample containers. Alternatively or additionally, the flow test unit can be mounted on the sample container at different times. It can be provided that the sample container has a predetermined breaking portion, which is penetrated by the penetration element of the flow test unit when the flow test unit is connected to the sample container, so that a liquid connection is established between the sample container and the flow test unit through the input port. As has been described in detail with respect to the flow test unit, the kit has the following advantages: the flow test unit can be used to check whether a specific substance is present in a sample contained in a closed sample container, in particular a hermetically sealed sample container, without having to remove the sample from the closed system, in particular a hermetically sealed system, or to establish a connection between the closed system and the environment, for example by having to open the system briefly. Through the connection of the flow test unit to the sample container, a liquid flows into the flow test unit through the established liquid connection and wets the test strip. A detection reaction can thus be initiated which takes place within a sealed housing, in particular a hermetically sealed housing, of the flow test cell.

[0028] Therefore, the invention also relates to the use of a flow test unit as described and claimed herein for performing a detection reaction on a sample. The sample is preferably provided in a sample container connected to the flow test unit, a liquid connection being established between the flow test unit and the sample container.

[0029] The invention further relates to the use of a flow test cell as described and claimed herein for connection to a sample container, in particular the connection site for establishing a liquid connection between the flow test cell and the sample container is liquid-tight. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] The present invention will now be described in detail with reference to various embodiments, but the present invention is not limited to these embodiments. The accompanying drawings are as follows:

[0031] Figure 1 A possible embodiment of the flow test unit according to the invention is shown in longitudinal section;

[0032] Figure 2 Show Figure 1 A perspective view of a flow test unit;

[0033] Figure 3 A possible embodiment of a kit according to the invention is shown, the kit comprising a flow test unit and a sample container in an unconnected state;

[0034] Figure 4 The process of connecting the flow test unit to the sample container via an input opening of the flow test unit and a predetermined breaking point in the outer wall of the sample container is shown, wherein, after the predetermined breaking point has been penetrated by means of the input opening, liquid flows from the sample container, which is in particular under pressure, into the interior of the flow test unit housing;

[0035] Figure 5 An embodiment of a kit according to the present invention is shown, which comprises a plurality of flow test units and a sample container, each flow test unit having a coupling portion, which is configured to be locked with a matching coupling portion, in particular a mechanical coupling portion, on an outer wall of the sample container, in particular matching with the mechanical coupling portion, so as to securely connect the flow test unit to the sample container;

[0036] Figure 6 The connection process between the flow test unit and the sample container is shown, wherein the in particular irreversible locking of the flow test unit on the outer wall of the sample container is shown in detail. DETAILED DESCRIPTION

[0037] Figure 1-6 A flow test unit is shown which is designated as a whole by the reference numeral 1 .

[0038] The flow test cell 1 is suitable for analyzing a sample in a housing 2 of the flow test cell 1 which is closed off to the outside.

[0039] The test strip 3 is embedded in the housing 2 and is surrounded by the housing 2. This can be, in particular, a housing 2 which is liquid-tight or closable, in particular in the connection position with the sample container 9.

[0040] The test strip 3 is provided for carrying out a detection reaction. This can be, for example, a test strip 3 known from the prior art. This can in particular be a test strip 3 consisting of at least one carrier and at least one flow layer arranged thereon. The substances required for carrying out the detection reaction can be applied to the flow layer, which serves as a reaction ligand for the substance to be detected in the sample and / or an interaction ligand for the substance to be detected. The detection reaction is initiated by contacting the substances required for the detection with the substance to be detected, and the user can preferably read the detection result directly from the test strip or indirectly with the aid of an auxiliary device.

[0041] The housing 2 has at least one input opening 4, which leads from the outside into an inflow chamber 17 of the housing 2. It can be provided that the input opening 4 is closed in the unconnected state of the flow test unit 1. For example, the input opening 4 can be closed by a thin wall embedded as a predetermined breaking point 21. The predetermined breaking point 21 can be penetrated here, for example, by a connection process with a sample container 9, so that a liquid connection 22 is formed between the flow test unit 1 and the sample holding space of the sample container 9.

[0042] The wetted area 5 of the test strip 3 is therefore arranged in the housing 2 in such a way that the wetted area 5 comes into contact with the liquid flowing into the interior of the housing 2 via the inlet opening 4. This allows the detection reaction to be initiated.

[0043] A coupling site 7 is formed on the outer side of the housing 2, by means of which the flow test unit 1 can be connected, in particular mechanically connected, to a matching mating coupling site 8 of the wall of a sample container 9. The flow test unit 1 can thus be irreversibly connected to the sample container 9. "Irreversible" in this case can mean that the sample container 9 cannot be separated from the flow test unit 1 in the case of proper use. In particular, it can be provided that no triggering mechanism is formed on the coupling site 7 and / or the mating coupling site 8 for cancelling the connection thereof.

[0044] In addition to the wetted area 5 already mentioned above, the test strip 3 may also have another area, which may be referred to as the analysis area 10. The detection reaction takes place in this area, which preferably does not come into direct contact with the liquid during use. The liquid 6 can be sucked in through the wetted area 5, preferably by capillary forces, and transported to the analysis area 10. For example, the test strip can be used to perform a lateral flow test, as is already known from the prior art.

[0045] like Figure 1 and 2 As shown, the flow test unit 1 has a pressure equalization device 11 on the housing 2. The pressure equalization device 11 is designed to equalize, for example, an overpressure existing in the sample container 9 after the sample container 9 is connected to the flow test unit 1, in particular until the external atmospheric pressure is present in the sample container 9 and / or a pressure balance is established between the pressure in the sample container 9 and the pressure in the flow test unit 1.

[0046] As in Figure 1 and 2 As can be seen in the figure, the pressure equalization device 11 can be designed, for example, as a pressure relief opening 12, through which the excess pressure can escape to the outside. The pressure equalization device 11 can be designed at the end opposite to the end at which the inlet opening 4 is provided. Therefore, the pressure equalization device 11 and the inlet opening 4 can be arranged spaced apart from each other in the axial direction. In particular, the pressure equalization device 11 can penetrate the wall of the analysis chamber 18 and / or be designed on the wall of the analysis chamber 18.

[0047] like Figure 2 As shown, the housing 2 has a first housing part 13 and a second housing part 14 which, in the assembled state, form a housing 2 which is closed toward the outside and is fluid-tight at least in the connected position.

[0048] The test strip 3 is inserted between the two housing parts 13 , 14 and is correctly positioned by means of a plurality of retaining tabs 15 .

[0049] Here, the test strip 3 is inserted between two pairs of holding tabs 15, each pair comprising two holding tabs. The distance between the two holding tabs 15 of a pair is selected to be greater than the thickness and / or wall thickness of the test strip 3. It is thus ensured that the holding tabs 15 do not squeeze the test strip 3, so that the liquid 6 can flow past the holding tabs 15 without hindrance through the test strip 3. The test strip 3 is thus held and laterally fixed by the holding tabs 15.

[0050] like Figure 1 , 4 As shown in Figures 6 and 7, the interior of the housing 2 is divided into two chambers 17 and 18 by a wall configured as an impact protection device 16. An inflow chamber 17 has the aforementioned input port 4, and the wetting area 5 is arranged in the inflow chamber 17. The analysis chamber 18 has a pressure relief port 12, and the analysis area 10 of the test strip 3 is arranged in the analysis chamber 18.

[0051] By forming the impact protection device 16, it is possible to prevent the liquid 6 from, for example, a sample container 9 under pressure from flowing into the flow test unit 1 in a surge-like manner, which would lead to an undesired wetting of the analysis area 10 of the test strip 3. The inflowing liquid is thus rebounded at the impact protection device 16 and flows back into the chamber 17. After the pressure balance occurs, it is provided that the liquid level of the liquid 6 in the housing 2 is below the impact protection device 16, i.e., does not rise into the analysis chamber 18.

[0052] The housing 2 of the flow test unit 1 is designed to be at least partially transparent, so that a user can see the test strip 3 , in particular the analysis area 10 of the test strip 3 , in order to be able to read the result of the test reaction. Figure 3 An embodiment is shown which has a viewing window which allows the test strip 3 to be seen from outside the housing 2 .

[0053] The inlet opening 4 is designed as a penetration element 19 which projects from the outer wall of the housing 2 obliquely or perpendicularly with respect to the longitudinal axis of the flow test cell 1 .

[0054] The sample container 9 may have a predetermined breaking point 21 on the outer wall.

[0055] When the flow test unit 1 is connected to the sample container 9, the penetration element 19 loads the predetermined breaking point 21 and penetrates it. Here, a liquid connection 22 is established between the sample holding space of the sample container 9 and the inflow chamber 17 of the flow test unit 1. The connection point between the flow test unit 1 and the sample container 9 is sufficiently sealed by the friction forces occurring between the parts in contact with each other to withstand, for example, a pressure higher than atmospheric pressure and present in the sample container 9. Alternatively or additionally, at least one additional sealing device can be provided at the connection point.

[0056] The penetrating element 19 can be designed, for example, as a nose 20 protruding in the radial and / or axial direction.

[0057] As already explained above, the input opening 4 can also have a predetermined breaking point 21, so that the housing 2 is closed to the outside in the unconnected state, in particular gas-tight. Through the connection process, this predetermined breaking point can also be penetrated by a further penetration element 19, which is formed, for example, on the outer wall of the sample container 9. However, this embodiment is not shown in the drawings.

[0058] In order to prevent the sample to be analyzed contained in the liquid 6 from contaminating the environment, the pressure equalization device 11 can have a barrier element 23, by which at least the liquid 6 is blocked. The barrier element can be, for example, a filter, the mesh width of which is selected accordingly to be impermeable to liquids, so that only gases can escape.

[0059] exist Figure 3 , 4 In the kit 100 including the flow test unit 1 and the sample container 9 shown in FIGS. 5 and 6 , the connection portion 7 of the flow test unit 1 is configured to correspond to the matching connection portion 8 on the outer wall of the sample container 9 .

[0060] The coupling part 7 comprises a prestressed spring element 26 which protrudes obliquely at one end of the housing 2. The spring element 26 is designed to generate a spring force which must be overcome in order to connect the flow test unit 1 to the sample container 9. The coupling part 7 has a latching element 27 at an opposite end of the housing 2. The latching element 27 can be designed, for example, as an axially protruding latching lug.

[0061] The mating connection point 8 comprises a mating latching element 28 corresponding to the spring element 26. The mating latching element 28 can be designed, for example, as an especially rigid latching hook which at least partially protrudes and / or loads and / or compresses the spring element 26 in the connected state.

[0062] Furthermore, the mating connection point 8 comprises a recess 29 which can be formed, for example, in a radial extension of the bottom of the sample container 9. Figure 4 and 6 shown.

[0063] In the connected state, the latching element 27 engages in the recess 29. Preferably, this forms a rotation axis about which the flow test unit 1 can be moved like a lever in the direction of the outer wall of the sample container 9 until the liquid connection 22 is established and a latching connection is formed between the spring element 26 and the mating latching element 28. Due to the lever action, the force required to penetrate the at least one predetermined breaking point 21 is relatively small.

[0064] Therefore, the present invention particularly relates to a flow test unit 1, which has a housing 2 that is sealed to the outside at least in the connection position with the sample container 9, the housing 2 includes at least one test strip 3, the housing 2 has at least one input port 4, and the test strip 3 is arranged in the housing 2 so that after establishing a liquid connection 22 with the sample container 9, the wetting area 5 can be wetted by the liquid 6 flowing in through the at least one input port 4.

[0065] Reference numerals list

[0066] 1Flow test unit

[0067] 2 Shell

[0068] 3 test strips

[0069] 4 Input ports

[0070] 5 Wetted Area

[0071] 6Liquid (including sample material to be analyzed)

[0072] 7Connection parts

[0073] 8. Mating connection parts

[0074] 9 Sample Containers

[0075] 10Analysis Area

[0076] 11Pressure balancing device

[0077] 12 Pressure relief port

[0078] 13 first housing component

[0079] 14 Second housing component

[0080] 15. Keep the tabs

[0081] 16 Impact protection device

[0082] 17 Inflow chamber

[0083] 18 Analysis Chamber

[0084] 19 Penetration element

[0085] 20 Nose

[0086] 21Predetermined fracture site

[0087] 22 Liquid Connections

[0088] 23 blocking elements

[0089] 24Connection parts

[0090] 25 Observation window

[0091] 26 Spring element

[0092] 27 Locking element

[0093] 28 Matching locking element

[0094] 29 concavity

[0095] 100 Kits

Claims

1. A flow test unit (1) having: a housing (2) closed toward the outside, said housing comprising at least one test strip (3), at least one inlet opening (4) in the housing (2), so that the housing is closed except for the at least one inlet opening, The at least one test strip (3) is arranged in the housing (2) in such a way that a wetting area (5) of the at least one test strip (3) can be wetted by a liquid (6) entering via the at least one inlet opening (4). The housing (2) has an impact protection device (16) in the interior, by which the interior of the housing (2) is divided into two chambers (17, 18), the impact protection device separating the wetting area (5) from the analysis area (10) of the at least one test strip (3), wherein The at least one test strip is positioned within a slot or cutout in the impact protection device (16) and extends through the slot or cutout to prevent the at least one test strip from being pinched, The housing (2) has an outer side, on which a coupling point (7) is arranged, and the flow test unit (1) is arranged to be connected to a matching coupling point (8) of a wall of a sample container (9) via the coupling point (7), and The housing (2) also has a pressure equalization device (11) to facilitate the inflow of liquid (6).

2. The flow test unit (1) according to claim 1, characterized in that When the wetted area (5) comes into contact with the liquid (6) to be analyzed, a detection reaction can be initiated and / or the test strip (3) is configured for performing a lateral flow test.

3. The flow test unit (1) according to claim 1 or 2, characterized in that: The housing (2) is constructed in at least two parts.

4. The flow test unit (1) according to claim 3, characterized in that The test strip (3) is embedded between at least two housing parts (13, 14).

5. The flow test unit (1) according to claim 3, characterized in that The housing (2) is designed in exactly two parts.

6. The flow test unit (1) according to claim 1 or 2, characterized in that: The at least one test strip (3) is held and / or laterally fixed by at least one holding web (15) of the housing (2).

7. The flow test unit (1) according to claim 1 or 2, characterized in that: The at least one test strip (3) is held and / or laterally fixed by at least one holding web (15) of the housing (2) so that the at least one test strip (3) lies against the at least one holding web and / or is not deformed by the at least one holding web (15).

8. The flow test unit (1) according to claim 1 or 2, characterized in that The wetting region (5) of the at least one test strip (3) is arranged in an inflow chamber (17) and the analysis region (10) of the at least one test strip (3) is arranged in an analysis chamber (18) of the housing (2).

9. The flow test unit (1) according to claim 1 or 2, characterized in that: The housing (2) is designed to be at least partially transparent and / or the housing (2) has a marking through which a user can read the analysis result.

10. The flow test unit (1) according to claim 1 or 2, characterized in that The at least one inlet opening (4) is designed as a penetration element (19), by means of which a predetermined breaking point (21) in a wall can be penetrated by a process of connecting the flow test cell (1) to the wall.

11. The flow test unit (1) according to claim 10, characterized in that The penetrating element (19) is a radially and / or axially protruding nose (20).

12. The flow test unit (1) according to claim 10, characterized in that The predetermined breaking point (21) in the wall can be penetrated by a connection process of the flow test unit (1) to the wall, so that a fluid connection (22) to the sample container (9) is established via the inlet opening (4).

13. The flow test unit (1) according to claim 1 or 2, characterized in that The pressure equalization device (11) has a blocking element (23) to prevent the liquid (6) from flowing out from the interior of the housing (2).

14. The flow test unit (1) according to claim 13, characterized in that The barrier element (23) is a filter.

15. A kit (100) comprising a flow test unit (1) according to any one of claims 1 to 14 and a sample container (9), characterized in that: The sample container (9) has a mating connection portion (8) that matches the connection portion (7) of the flow test unit (1).

16. The kit (100) according to claim 15, characterized in that The sample container (9) has a predetermined breaking point (21), which is penetrated by a penetration element (19) of the flow test unit (1) when the flow test unit (1) is connected to the sample container (9), thereby establishing a liquid connection (22) between the sample container (9) and the flow test unit (1) through the input port (4).

17. Use of the flow test unit (1) according to any one of claims 1 to 14 for performing a detection reaction on a sample.

18. The use according to claim 17, characterized in that A sample is provided in a sample container (9) connected to the flow test unit (1), and a liquid connection (22) is established between the flow test unit (1) and the sample container (9).

19. Use of the flow test unit (1) according to any one of claims 1 to 14 for connection to a sample container (9).

20. The use according to claim 19, characterized in that The connection point (24) for establishing the liquid connection (22) between the flow test unit (1) and the sample container (9) is liquid-tight.

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