A method and apparatus for detecting sound attenuation, and a storage medium.

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By extracting the fundamental and harmonic signals from the ultrasonic echo and calculating the acoustic attenuation-related parameters, the problem of low accuracy in single-frequency detection is solved, and more accurate tissue attenuation characteristic analysis is achieved.

CN112237445BActive Publication Date: 2026-05-26SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD

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Patent Information

Authority / Receiving Office: CN · China
Patent Type: Patents(China)
Current Assignee / Owner: SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
Filing Date: 2019-07-16
Publication Date: 2026-05-26

Application Information

Patent Timeline

16 Jul 2019

Application

26 May 2026

Publication

CN112237445B

IPC: A61B8/08

CPC: A61B8/0858; A61B8/5215

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Application Domain

Organ movement/changes detection Ultrasonic/sonic/infrasonic dianostic techniques

Technology Topics

Harmonic Target tissue

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AI Technical Summary

Technical Problem

In existing technologies, using ultrasound at a single frequency point to detect acoustic attenuation parameters cannot fully describe the attenuation characteristics of tissues, resulting in low detection accuracy.

Method used

By extracting the fundamental and harmonic signals from the ultrasonic echo, calculating the fundamental and harmonic acoustic intensity parameters, and combining the depth difference and transmission frequency, calculating the fundamental and harmonic acoustic attenuation parameters, the attenuation characteristics of the target tissue are comprehensively determined.

Benefits of technology

It improves the accuracy of acoustic attenuation detection and can more comprehensively describe the attenuation characteristics of tissues.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

This invention discloses a method, apparatus, and storage medium for detecting acoustic attenuation. The method may include: receiving ultrasonic echoes from a target tissue; extracting fundamental and harmonic signals from the ultrasonic echoes; obtaining a first fundamental acoustic intensity parameter at a first preset depth and a second fundamental acoustic intensity parameter at a second preset depth using the fundamental signal; obtaining the first harmonic acoustic intensity parameter at the first preset depth and the second harmonic acoustic intensity parameter at the second preset depth using the harmonic signal; calculating fundamental acoustic attenuation-related parameters using the first and second fundamental acoustic intensity parameters; calculating harmonic acoustic attenuation-related parameters using the first and second harmonic acoustic intensity parameters; and determining the attenuation characteristics of the target tissue using the fundamental and harmonic acoustic attenuation-related parameters.

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Description

Technical Field

[0001] This invention relates to the field of ultrasound imaging, and more particularly to a method and apparatus for detecting acoustic attenuation, and a storage medium. Background Technology

[0002] When ultrasound waves propagate within human tissues, their energy attenuates due to effects such as diffusion, scattering, reflection, and absorption. Generally, the deeper the propagation and the higher the ultrasound frequency, the faster the attenuation. Different tissues exhibit different degrees of sound attenuation. For example, the attenuation coefficient is lower in water and higher in adipose tissue; therefore, the same ultrasound wave travels a greater distance in water than in adipose tissue. For soft tissues, the attenuation may increase with increasing fat content. Therefore, extracting sound attenuation parameters from tissues can reflect the degree of fatty tissue formation, such as the extent of fatty liver.

[0003] In existing technologies, ultrasound probes emit ultrasound waves at a specific frequency into tissue and receive the echoes. The acoustic attenuation parameters are then calculated by comparing the amplitudes of the ultrasound echoes at different depths. However, because the attenuation process of sound waves in tissue is not completely linear, the acoustic attenuation parameters obtained from ultrasound waves of different frequencies often differ. Therefore, the result from a single frequency point is insufficient to comprehensively describe the attenuation characteristics of the entire target tissue, leading to low accuracy in acoustic attenuation detection. Summary of the Invention

[0004] To address the aforementioned technical problems, embodiments of the present invention aim to provide a sound attenuation detection method, apparatus, and storage medium, which can improve the accuracy of sound attenuation detection.

[0005] In one embodiment, a method for detecting acoustic attenuation is provided. The method includes: receiving an ultrasonic echo from a target tissue; extracting a fundamental wave signal and harmonic signals from the ultrasonic echo; using the fundamental wave signal to obtain a first fundamental wave acoustic intensity parameter at a first preset depth and a second fundamental wave acoustic intensity parameter at a second preset depth; using the harmonic signals to obtain the first harmonic acoustic intensity parameter at the first preset depth and the second harmonic acoustic intensity parameter at the second preset depth; calculating a fundamental wave acoustic attenuation-related parameter using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter; calculating a harmonic acoustic attenuation-related parameter using the first harmonic acoustic intensity parameter and the second harmonic acoustic attenuation-related parameter; and determining the attenuation characteristics of the target tissue using the fundamental wave acoustic attenuation-related parameter and the harmonic acoustic attenuation-related parameter.

[0006] In this embodiment, the ultrasonic echo received from the target tissue may originate from the same ultrasonic beam emitted at the same time, or from the same or the same group of ultrasonic beams, or from ultrasonic beams emitted at different times, or from different or different groups of ultrasonic beams.

[0007] In this embodiment, the first preset depth and the second preset depth are different.

[0008] In one embodiment, calculating the fundamental wave attenuation related parameter using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter includes: calculating a first fundamental wave acoustic attenuation coefficient based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, the depth difference, and the transmission frequency, and determining the first fundamental wave acoustic attenuation coefficient as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave acoustic ... The attenuation parameter is determined as a fundamental sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the fundamental sound intensity parameter difference is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter difference is determined as the fundamental sound attenuation related parameter; or, the fundamental sound intensity parameter ratio is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter ratio is determined as the fundamental sound attenuation related parameter; or, the fundamental sound attenuation related parameter is obtained by fitting the first fundamental sound intensity parameter and the second fundamental sound intensity parameter.

[0009] In one embodiment, calculating the harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: calculating a first harmonic sound attenuation coefficient based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, and determining the first harmonic sound attenuation coefficient as the harmonic sound attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted towards the target tissue; or, calculating the first harmonic attenuation parameter based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference ... The attenuation parameter is determined as a harmonic sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the harmonic sound intensity parameter difference is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the harmonic sound intensity parameter difference is determined as a harmonic sound attenuation related parameter; or, the ratio of the harmonic sound intensity parameters is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the ratio of the harmonic sound intensity parameters is determined as a harmonic sound attenuation related parameter; or, the first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameter.

[0010] In one embodiment, the attenuation characteristics of a target tissue are determined using fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, including: calculating the parameter ratio or mean value between the fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, and using the parameter ratio or mean value to determine the attenuation characteristics of the target tissue.

[0011] In one embodiment, the fundamental sound attenuation related parameters are calculated using a first fundamental sound intensity parameter and a second fundamental sound intensity parameter; after calculating the harmonic sound attenuation related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the method further includes: displaying the fundamental sound attenuation related parameters and / or the harmonic sound attenuation related parameters.

[0012] In one embodiment, a method for detecting acoustic attenuation is provided. The method includes: receiving a first ultrasonic echo from a target tissue; extracting a fundamental wave signal from the first ultrasonic echo; receiving a second ultrasonic echo from the target tissue; extracting harmonic signals from the second ultrasonic echo; obtaining a first fundamental wave acoustic intensity parameter at a first preset depth and a second fundamental wave acoustic intensity parameter at a second preset depth using the fundamental wave signal; obtaining a first harmonic acoustic intensity parameter at a first preset depth and a second harmonic acoustic intensity parameter at a second preset depth using the harmonic signals; calculating fundamental wave acoustic attenuation-related parameters using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter; calculating harmonic acoustic attenuation-related parameters using the first harmonic acoustic intensity parameter and the second harmonic acoustic intensity parameter; and determining the attenuation characteristics of the target tissue using the fundamental wave acoustic attenuation-related parameters and the harmonic acoustic attenuation-related parameters.

[0013] In this embodiment, the first ultrasonic echo and the second ultrasonic echo can be obtained by the same ultrasonic probe or by different ultrasonic probes.

[0014] In this embodiment, the first preset depth and the second preset depth are different.

[0015] In one embodiment, calculating the fundamental wave attenuation related parameter using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter includes: calculating a first fundamental wave acoustic attenuation coefficient based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, the depth difference, and the transmission frequency, and determining the first fundamental wave acoustic attenuation coefficient as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave acoustic ... The attenuation parameter is determined as a fundamental sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the fundamental sound intensity parameter difference is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter difference is determined as the fundamental sound attenuation related parameter; or, the fundamental sound intensity parameter ratio is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter ratio is determined as the fundamental sound attenuation related parameter; or, the fundamental sound attenuation related parameter is obtained by fitting the first fundamental sound intensity parameter and the second fundamental sound intensity parameter.

[0016] In one embodiment, calculating the harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: calculating a first harmonic sound attenuation coefficient based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, and determining the first harmonic sound attenuation coefficient as the harmonic sound attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted towards the target tissue; or, calculating the first harmonic attenuation parameter based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference ... The attenuation parameter is determined as a harmonic sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the harmonic sound intensity parameter difference is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the harmonic sound intensity parameter difference is determined as a harmonic sound attenuation related parameter; or, the ratio of the harmonic sound intensity parameters is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the ratio of the harmonic sound intensity parameters is determined as a harmonic sound attenuation related parameter; or, the first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameter.

[0017] In one embodiment, the attenuation characteristics of a target tissue are determined using fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, including: calculating the parameter ratio or mean value between the fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, and using the parameter ratio or mean value to determine the attenuation characteristics of the target tissue.

[0018] In one embodiment, a method for detecting acoustic attenuation is provided. The method includes: transmitting a first ultrasonic wave to a target tissue at a first frequency; receiving the echo of the first ultrasonic wave from the target tissue to obtain a first ultrasonic echo; transmitting a second ultrasonic wave to the target tissue at a second frequency; receiving the echo of the second ultrasonic wave from the target tissue to obtain a second ultrasonic echo; extracting a first fundamental wave signal and a first harmonic signal from the first ultrasonic echo; extracting a second fundamental wave signal and a second harmonic signal from the second ultrasonic echo; calculating fundamental wave acoustic attenuation related parameters based on the first fundamental wave signal and the second fundamental wave signal; calculating harmonic acoustic attenuation related parameters based on the first harmonic signal and the second harmonic signal; and determining the attenuation characteristics of the target tissue using the fundamental wave acoustic attenuation related parameters and the harmonic acoustic attenuation related parameters.

[0019] In this embodiment, the first frequency point and the second frequency point may be different, and the first ultrasonic wave and the second ultrasonic wave may be emitted by the same probe or by different probes.

[0020] In this embodiment, the first preset depth and the second preset depth are different.

[0021] In one embodiment, calculating the fundamental acoustic attenuation related parameters based on the first fundamental signal and the second fundamental signal includes: obtaining a first fundamental acoustic intensity parameter at a first preset depth based on the first fundamental signal; obtaining a second fundamental acoustic intensity parameter at a second preset depth based on the second fundamental signal; and calculating the fundamental acoustic attenuation related parameters using the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter.

[0022] In one embodiment, calculating the harmonic sound attenuation related parameters based on the first harmonic signal and the second harmonic signal includes: obtaining a first harmonic sound intensity parameter at a first preset depth based on the first harmonic signal; obtaining a second harmonic sound intensity parameter at a second preset depth based on the second harmonic signal; and calculating the harmonic sound attenuation related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

[0023] In one embodiment, calculating the fundamental wave attenuation related parameter using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter includes: calculating a first fundamental wave acoustic attenuation coefficient based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, the depth difference, and the transmission frequency, and determining the first fundamental wave acoustic attenuation coefficient as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave attenuation parameter based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, and determining the first fundamental wave acoustic attenuation related parameter as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasound waves are emitted to the target tissue; or, calculating the first fundamental wave acoustic ... The attenuation parameter is determined as a fundamental sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the fundamental sound intensity parameter difference is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter difference is determined as the fundamental sound attenuation related parameter; or, the fundamental sound intensity parameter ratio is calculated based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and the fundamental sound intensity parameter ratio is determined as the fundamental sound attenuation related parameter; or, the fundamental sound attenuation related parameter is obtained by fitting the first fundamental sound intensity parameter and the second fundamental sound intensity parameter.

[0024] In one embodiment, calculating the harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: calculating a first harmonic sound attenuation coefficient based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, and determining the first harmonic sound attenuation coefficient as the harmonic sound attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted towards the target tissue; or, calculating the first harmonic attenuation parameter based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference ... The attenuation parameter is determined as a harmonic sound attenuation related parameter, where the depth difference is the depth difference between a first preset depth and a second preset depth; or, the harmonic sound intensity parameter difference is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the harmonic sound intensity parameter difference is determined as a harmonic sound attenuation related parameter; or, the ratio of the harmonic sound intensity parameters is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and the ratio of the harmonic sound intensity parameters is determined as a harmonic sound attenuation related parameter; or, the first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameter.

[0025] In one embodiment, the attenuation characteristics of a target tissue are determined using fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, including: calculating the parameter ratio or mean value between the fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, and using the parameter ratio or mean value to determine the attenuation characteristics of the target tissue.

[0026] In one embodiment, a method for detecting acoustic attenuation is provided. The method includes: receiving ultrasonic echoes from a target tissue; acquiring fundamental acoustic intensity parameters at at least two preset depths using the ultrasonic echoes; acquiring harmonic acoustic intensity parameters at at least two preset depths using the ultrasonic echoes; calculating fundamental acoustic attenuation-related parameters using the fundamental acoustic intensity parameters at the at least two preset depths; calculating harmonic acoustic attenuation-related parameters using the harmonic acoustic intensity parameters at the at least two preset depths; and determining the attenuation characteristics of the target tissue using the fundamental acoustic attenuation-related parameters and the harmonic acoustic attenuation-related parameters.

[0027] In this embodiment, the ultrasonic echo received from the target tissue may originate from the same ultrasonic beam emitted at the same time, or from the same or the same group of ultrasonic beams, or from ultrasonic beams emitted at different times, or from different or different groups of ultrasonic beams.

[0028] In one embodiment, a method for detecting acoustic attenuation is provided, the method comprising: receiving an ultrasonic echo from a target tissue; extracting a fundamental wave signal and harmonic signals from the ultrasonic echo; calculating fundamental wave acoustic attenuation related parameters using the fundamental wave signal; calculating harmonic acoustic attenuation related parameters using the harmonic signals; and determining the attenuation characteristics of the target tissue using the fundamental wave acoustic attenuation related parameters and the harmonic acoustic attenuation related parameters.

[0029] In one embodiment, an acoustic attenuation detection device is provided, comprising: an ultrasonic probe; a transmitting circuit that excites the ultrasonic probe to emit ultrasonic waves toward a target tissue; a receiving circuit that receives ultrasonic echoes returned from the target tissue via the ultrasonic probe; a processor that processes the echo signals to obtain an ultrasonic image of the target tissue; and a display that displays the ultrasonic image. Specifically, the processor performs the following steps: extracting a fundamental wave signal and harmonic signals from the ultrasonic echo; using the fundamental wave signal to obtain a first fundamental wave acoustic intensity parameter at a first preset depth and a second fundamental wave acoustic intensity parameter at a second preset depth; using the harmonic signals to obtain the first harmonic acoustic intensity parameter at the first preset depth and the second harmonic acoustic intensity parameter at the second preset depth; calculating fundamental wave acoustic attenuation-related parameters using the first and second fundamental wave acoustic intensity parameters; calculating harmonic acoustic attenuation-related parameters using the first and second harmonic acoustic intensity parameters; and determining the attenuation characteristics of the target tissue using the fundamental wave acoustic attenuation-related parameters and the harmonic acoustic attenuation-related parameters.

[0030] In one embodiment, the processor: calculates a first fundamental acoustic attenuation coefficient based on a first fundamental acoustic intensity parameter, a second fundamental acoustic intensity parameter, a depth difference, and a transmission frequency, and determines the first fundamental acoustic attenuation coefficient as a fundamental acoustic attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted towards the target tissue; or, calculates a first fundamental acoustic attenuation parameter based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, and the depth difference, and determines the first fundamental acoustic attenuation parameter as a fundamental acoustic attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth; or, calculates the difference in fundamental acoustic intensity parameters based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, and determines the difference in fundamental acoustic intensity parameters as a fundamental acoustic attenuation-related parameter; or, calculates the ratio of fundamental acoustic intensity parameters based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, and determines the ratio of fundamental acoustic intensity parameters as a fundamental acoustic attenuation-related parameter; or, fits the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter to obtain a fundamental acoustic attenuation-related parameter.

[0031] In one embodiment, the processor: calculates a first harmonic attenuation coefficient based on a first harmonic sound intensity parameter, a second harmonic sound intensity parameter, a depth difference, and a transmission frequency, and determines the first harmonic sound attenuation coefficient as a harmonic sound attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted towards the target tissue; or, calculates a first harmonic attenuation parameter based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and a depth difference, and determines the first harmonic attenuation parameter as a harmonic sound attenuation-related parameter, wherein the depth difference is the depth difference between a first preset depth and a second preset depth; or, calculates the harmonic sound intensity parameter difference based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and determines the harmonic sound intensity parameter difference as a harmonic sound attenuation-related parameter; or, calculates the harmonic sound intensity parameter ratio based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and determines the harmonic sound intensity parameter ratio as a harmonic sound attenuation-related parameter; or, fits the first harmonic sound intensity parameter and the second harmonic sound intensity parameter to obtain the harmonic sound attenuation-related parameter.

[0032] In one embodiment, the processor is further configured to calculate the ratio or mean of the fundamental acoustic attenuation-related parameters and the harmonic acoustic attenuation-related parameters, and to use the ratio or mean of the parameters to determine the attenuation characteristics of the target tissue.

[0033] In one embodiment, the display is also used to display fundamental sound attenuation-related parameters and / or harmonic sound attenuation-related parameters.

[0034] In one embodiment, a storage medium is provided that stores a computer program that can be executed by a processor to implement the sound attenuation detection method in any of the foregoing embodiments.

[0035] In the embodiments described herein, the fundamental acoustic intensity parameter mentioned can be the fundamental signal energy, fundamental signal strength, fundamental signal amplitude, or other suitable parameters reflecting the fundamental intensity, and the harmonic acoustic intensity parameter mentioned can be the harmonic signal energy, harmonic signal strength, harmonic signal amplitude, or other suitable parameters reflecting the harmonic intensity.

[0036] In this embodiment of the invention, after receiving an ultrasonic echo from the target tissue, the acoustic attenuation detection device extracts the fundamental wave signal and harmonic signals from the ultrasonic echo signal, and generates fundamental wave acoustic attenuation related parameters based on the fundamental wave signal; it also generates harmonic acoustic attenuation parameters based on the harmonic signals. Subsequently, the acoustic attenuation detection device determines the attenuation characteristics of the target tissue based on the fundamental wave acoustic attenuation parameters and harmonic acoustic attenuation parameters. It can utilize different frequency components in the ultrasonic echo to jointly describe the attenuation characteristics of the entire target tissue, thereby improving the accuracy of acoustic attenuation detection. Attached Figure Description

[0037] Figure 1 This is a schematic diagram of a sound attenuation detection device provided in an embodiment of the present invention;

[0038] Figure 2 A flowchart of a sound attenuation detection method provided in an embodiment of the present invention. Figure 1 ;

[0039] Figure 3(a) is a schematic diagram of an exemplary linear array probe provided in an embodiment of the present invention;

[0040] Figure 3(b) is a scanning schematic diagram of an exemplary convex array probe and a phased array probe provided in an embodiment of the present invention;

[0041] Figure 4 An exemplary graph showing the relationship between the propagation depth and sound intensity parameters of ultrasound in a target tissue, provided as an embodiment of the present invention;

[0042] Figure 5 A module composition diagram of an exemplary sound attenuation detection device provided in an embodiment of the present invention;

[0043] Figure 6 A flowchart of a sound attenuation detection method provided in this application embodiment Figure 2 . Detailed Implementation

[0044] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.

[0045] This invention provides a method for detecting sound attenuation, which is applied to a sound attenuation detection device 10, such as... Figure 1 As shown, the acoustic attenuation detection device 10 may include an ultrasound probe 100, a transmitting circuit 101, a transmit / receive selection switch 102, a receiving circuit 103, a beamforming circuit 104, a processor 105, and a display 106. The transmitting circuit 101 can excite the ultrasound probe 100 to emit ultrasound waves towards the target tissue. The receiving circuit 103 can receive the ultrasound echoes returning from the target tissue via the ultrasound probe 100. The echo signal / data is processed by the beamforming circuit 104 and then sent to the processor 105. The processor 105 processes the echo signal / data to obtain an ultrasound image of the target tissue. The ultrasound images obtained by the processor 105 can be stored in a memory 107. These ultrasound blood flow images can be displayed on the display 106.

[0046] In this embodiment, the display 106 of the aforementioned acoustic attenuation detection device 10 can be a touch screen, liquid crystal display, or an independent display device such as a liquid crystal display or a television set, separate from the ultrasound vector blood flow imaging device 10. It can also be a display screen on an electronic device such as a mobile phone or tablet computer.

[0047] In this embodiment of the application, the memory 107 of the aforementioned sound attenuation detection device 10 can be a flash memory card, solid-state memory, hard disk, etc.

[0048] Specifically, the processor 105 performs the following steps: extracting the fundamental wave signal and harmonic signals from the ultrasonic echo; using the fundamental wave signal to obtain a first fundamental wave sound intensity parameter at a first preset depth and a second fundamental wave sound intensity parameter at a second preset depth; using the harmonic signals to obtain a first harmonic sound intensity parameter at a first preset depth and a second harmonic sound intensity parameter at a second preset depth; using the first fundamental wave sound intensity parameter and the second fundamental wave sound intensity parameter to calculate fundamental wave sound attenuation related parameters; using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter to calculate harmonic sound attenuation related parameters; and using the fundamental wave sound attenuation related parameters and harmonic sound attenuation related parameters to determine the attenuation characteristics of the target tissue.

[0049] In this article, the “sound intensity parameter” can be any parameter that can reflect the intensity of the echo signal, such as signal amplitude, signal energy, signal power, etc. When it is the signal amplitude, it can be the signal amplitude expressed in the original unit or the signal amplitude after being converted to dB unit.

[0050] For example, the fundamental wave acoustic intensity parameter mentioned in this article can be the fundamental wave signal energy, fundamental wave signal intensity, fundamental wave signal amplitude, or other suitable parameters reflecting the fundamental wave intensity; the harmonic acoustic intensity parameter mentioned can be the harmonic signal energy, harmonic signal intensity, harmonic signal amplitude, or other suitable parameters reflecting the harmonic intensity.

[0051] For example, for a signal that has been quadratured to obtain two data streams, I and Q, its amplitude can be sqrt(I). 2 +Q 2 Its energy can be I 2 +Q 2 ,etc.

[0052] Optionally, the processor 105 is further configured to calculate a first fundamental acoustic attenuation coefficient based on a first fundamental acoustic intensity parameter, a second fundamental acoustic intensity parameter, a depth difference, and a transmission frequency, wherein the depth difference is the depth difference between a first preset depth and a second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; determine the first fundamental acoustic attenuation coefficient as a fundamental acoustic attenuation related parameter; calculate a first harmonic acoustic attenuation coefficient based on a first harmonic acoustic intensity parameter, a second harmonic acoustic intensity parameter, a depth difference, and a transmission frequency; and determine the first harmonic acoustic attenuation coefficient as a harmonic acoustic attenuation related parameter.

[0053] Optionally, the processor 105 is further configured to calculate a first fundamental wave attenuation parameter based on the first fundamental wave sound intensity parameter, the second fundamental wave sound intensity parameter, and the depth difference; determine the first fundamental wave attenuation parameter as a fundamental wave sound attenuation related parameter; calculate a first harmonic attenuation parameter based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference; and determine the first harmonic attenuation parameter as a harmonic sound attenuation related parameter.

[0054] Optionally, the processor 105 is further configured to calculate the difference between the fundamental sound intensity parameters based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and determine the difference between the fundamental sound intensity parameters as a fundamental sound attenuation related parameter; and to calculate the difference between the harmonic sound intensity parameters based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and determine the difference between the harmonic sound intensity parameters as a harmonic sound attenuation related parameter.

[0055] Optionally, the processor 105 is further configured to calculate the ratio of fundamental sound intensity parameters based on the first fundamental sound intensity parameter and the second fundamental sound intensity parameter, and determine the ratio of fundamental sound intensity parameters as a fundamental sound attenuation related parameter; and to calculate the ratio of harmonic sound intensity parameters based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, and determine the ratio of harmonic sound intensity parameters as a harmonic sound attenuation related parameter.

[0056] Optionally, the processor 105 is also used to calculate the ratio or mean of the parameters between the fundamental acoustic attenuation parameters and the harmonic acoustic attenuation parameters, and to use the ratio or mean of the parameters to determine the attenuation characteristics of the target tissue.

[0057] Optionally, the display 106 is also used to display fundamental sound attenuation related parameters and harmonic sound attenuation related parameters.

[0058] Optionally, the transmitting circuit 101 is also used to transmit ultrasound waves at at least one preset transmitting frequency point to the target tissue using at least one ultrasound probe.

[0059] Optionally, the receiving circuit 103 is also configured to receive an ultrasonic echo from a target tissue at least one preset transmission frequency point using at least one ultrasonic probe, wherein one of the at least one ultrasonic probes receives an ultrasonic echo from a preset transmission frequency point.

[0060] Optionally, the processor 105 is further configured to acquire at least one fundamental acoustic attenuation related parameter and at least one harmonic acoustic attenuation related parameter corresponding to at least one preset transmission frequency point; combine at least one fundamental acoustic attenuation related parameter and at least one harmonic acoustic attenuation related parameter to obtain multi-frequency acoustic attenuation related parameters; and use the multi-frequency acoustic attenuation related parameters to determine the attenuation characteristics of the target tissue.

[0061] Optionally, the transmitting circuit 101 is also used to transmit ultrasound waves at a first preset transmission frequency point to the target tissue using at least one ultrasound probe, the first preset transmission frequency point being the same as the fundamental frequency of the fundamental signal.

[0062] Optionally, the receiving circuit 103 is also configured to receive a fundamental wave signal from the target tissue using a first ultrasonic probe, wherein the first ultrasonic probe is any one of at least one ultrasonic probes; and to receive a harmonic signal from the target tissue using a second ultrasonic probe, wherein the second ultrasonic probe is any one of at least one ultrasonic probes other than the first ultrasonic probe.

[0063] This application also provides a computer-readable storage medium storing multiple program instructions. After being called and executed by the processor 105, the multiple program instructions can execute some or all of the steps or any combination of the steps in the sound attenuation detection method in various embodiments of this application.

[0064] In one embodiment, the computer-readable storage medium may be a memory 107, which may be a non-volatile storage medium such as a flash memory card, a solid-state memory, or a hard disk.

[0065] In this embodiment, the processor 105 of the aforementioned sound attenuation detection device 10 can be implemented by software, hardware, firmware, or a combination thereof. It can use circuits, one or more application-specific integrated circuits (ASICs), one or more general-purpose integrated circuits, one or more microprocessors, one or more programmable logic devices, or a combination of the aforementioned circuits or devices, or other suitable circuits or devices, so that the processor 105 can execute the corresponding steps of the sound attenuation detection method in the aforementioned embodiments.

[0066] The acoustic attenuation detection method in this application is described in detail below. (See also...) Figure 2 .

[0067] S101, Receive ultrasound echoes from the target tissue.

[0068] The acoustic attenuation detection method provided in this embodiment of the invention is applicable to scenarios where the degree of fatty tissue deposition in a target tissue is determined based on the acoustic attenuation parameters of the target tissue.

[0069] The acoustic attenuation detection method provided in this invention is currently mainly used in clinical practice for the assessment of fatty liver, the optimization of B-image quality, or the assessment of fat content in other tissues (such as body surface tissue).

[0070] In this embodiment of the invention, the transmitting circuit of the acoustic attenuation detection device excites at least one ultrasonic probe to emit ultrasonic waves at at least one preset emission point toward the target tissue. Then, the receiving circuit of the acoustic attenuation detection device excites at least one ultrasonic probe to receive ultrasonic echoes at at least one preset emission point from the target tissue.

[0071] In this embodiment of the invention, the acoustic attenuation detection device uses an ultrasonic probe to sequentially emit ultrasonic waves to the target tissue at at least one preset emission frequency point, and uses the same ultrasonic probe to sequentially receive corresponding ultrasonic echoes from the target tissue.

[0072] In this embodiment of the invention, the acoustic attenuation detection device uses two ultrasonic probes to emit ultrasonic waves to the target tissue at a preset emission frequency. Then, one of the ultrasonic probes receives the fundamental wave portion of the ultrasonic echo from the target tissue, and the other ultrasonic probe receives the harmonic portion of the ultrasonic echo from the target tissue.

[0073] In this embodiment of the invention, the acoustic attenuation detection device is equipped with multiple ultrasonic probes. The acoustic attenuation detection device uses one ultrasonic probe to emit ultrasonic waves to the target tissue according to a preset emission frequency point, and uses the same ultrasonic probe to receive ultrasonic echoes from the target tissue. Thus, the acoustic attenuation detection device uses multiple ultrasonic probes to obtain ultrasonic echoes corresponding to multiple preset emission frequency points.

[0074] In this embodiment of the invention, the type of ultrasonic probe may include convex array probes, linear array probes, and phased array probes, etc. The specific type may be selected according to the actual situation, and this embodiment of the invention does not impose any specific limitations.

[0075] For example, as shown in Figure 3(a), the scanning direction of the linear array probe is parallel scanning; as shown in Figure 3(b), the scanning direction of the convex array probe and the phased array probe is generally convex or fan-shaped scanning.

[0076] S102. Extract the fundamental wave signal and harmonic signal from the ultrasonic echo.

[0077] After the acoustic attenuation detection device receives the ultrasonic echo from the target tissue, it extracts the fundamental wave signal and harmonic signal from the ultrasonic echo.

[0078] In this embodiment of the invention, the harmonic signals include second harmonics, third harmonics, fourth harmonics, etc. In practical applications, since the sound intensity parameters of third harmonics, fourth harmonics, etc. are relatively weak, the second harmonic signal in the ultrasonic echo is selected as the harmonic signal used in this embodiment of the invention.

[0079] In this embodiment of the invention, the sound attenuation detection device determines the echo signal with the same frequency as the preset transmission frequency as the fundamental signal, and determines the echo signal with a frequency twice that of the preset transmission frequency as the second harmonic signal.

[0080] In this embodiment of the invention, the acoustic attenuation detection device utilizes harmonic separation technology to extract harmonic signals from the ultrasound echo. Optionally, the harmonic separation technology can refer to commonly used methods in ultrasound tissue harmonic imaging, including the natural filtering method, which extracts harmonic signals by setting a specific filter; the positive and negative pulse weighted cancellation method; the offset pulse weighted method, etc. The specific method is selected according to the actual situation, and this embodiment of the invention does not impose specific limitations.

[0081] S103. Obtain the first fundamental acoustic intensity parameter at the first preset depth and the second fundamental acoustic intensity parameter at the second preset depth using the fundamental signal.

[0082] After the acoustic attenuation detection device extracts the fundamental wave signal and harmonic signal from the ultrasonic echo, the acoustic attenuation detection device uses the fundamental wave signal to obtain the first fundamental wave acoustic intensity parameter at the first preset depth and the second fundamental wave acoustic intensity parameter at the second preset depth.

[0083] In this embodiment of the invention, the acoustic attenuation detection device is pre-set with a first preset depth and a second preset depth. After the acoustic attenuation detection device extracts the fundamental wave signal from the ultrasonic echo signal, it obtains the first fundamental wave acoustic intensity parameter of the fundamental wave signal from the first preset depth and the second fundamental wave acoustic intensity parameter of the fundamental wave signal from the second preset depth.

[0084] For example, the attenuation relationship of ultrasound waves at a preset emission frequency with depth in tissue is as follows: Figure 4 As shown, for ultrasound with the same transmission frequency, the dB number of its sound intensity parameter has an approximately linear relationship with the propagation depth. Ultrasound with different depths has different sound intensity parameters.

[0085] S104. Obtain the first harmonic sound intensity parameter at the first preset depth and the second harmonic sound intensity parameter at the second preset depth using harmonic signals.

[0086] After the acoustic attenuation detection device extracts the fundamental and harmonic signals from the ultrasonic echo, it uses the harmonic signals to obtain the first harmonic sound intensity parameter at a first preset depth and the second harmonic sound intensity parameter at a second preset depth.

[0087] In this embodiment of the invention, the sound attenuation detection device acquires the first harmonic signal corresponding to the harmonic signal at a first preset depth, and acquires the second harmonic signal corresponding to the harmonic signal at a second preset depth.

[0088] It should be noted that S103 and S104 are two parallel steps following S102, and the specific steps to be executed are selected according to the actual situation. This embodiment of the invention does not impose specific limitations.

[0089] S105. Calculate the fundamental wave attenuation related parameters using the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter.

[0090] After the sound attenuation detection device obtains the first fundamental sound intensity parameter at the first preset depth and the second fundamental sound intensity parameter at the second preset depth using the fundamental signal, the sound attenuation detection device calculates the fundamental sound attenuation related parameters using the first fundamental sound intensity parameter and the second fundamental sound intensity parameter.

[0091] In this embodiment of the invention, the fundamental sound attenuation related parameter can be the first fundamental sound attenuation coefficient. The sound attenuation detection device calculates the first fundamental sound attenuation coefficient based on the first fundamental sound intensity parameter, the second fundamental sound intensity parameter, the depth difference, and the transmission frequency. The depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted to the target tissue.

[0092] It should be noted that the acoustic intensity parameter obtained at a specific depth (such as depth1) in the ultrasonic echo is actually the result after the ultrasonic wave has propagated a distance of (2*depth1) and attenuated. The difference in the acoustic intensity parameters of the ultrasonic echo within a depth interval (such as depth1 and depth2, assuming depth1 < depth2) is actually the result after the ultrasonic wave has propagated a distance of (2*depth2 - 2*depth1) and attenuated.

[0093] In one embodiment, taking the signal amplitude after converting the acoustic intensity parameter to dB as an example, the calculation formula for the first fundamental wave acoustic attenuation coefficient can be Formula (1)

[0094] First fundamental wave acoustic attenuation coefficient = (fundamental wave signal amplitude at depth2 - fundamental wave signal amplitude at depth1) / (2*(depth2 - depth1)) / FC (1)

[0095] Where, depth1 is the first preset depth, depth2 is the second preset depth, then depth2 - depth1 is the depth difference, the fundamental wave signal amplitude at depth1 is the first fundamental wave signal amplitude, the fundamental wave signal amplitude at depth2 is the second fundamental wave signal amplitude, and FC is the transmission frequency.

[0096] In this embodiment, the common unit of the first fundamental wave acoustic attenuation coefficient is dB / cm / MHz.

[0097] In the embodiment of the present invention, Formula (1) can be transformed, and the first fundamental wave attenuation parameter is used as the fundamental wave acoustic attenuation related parameter. Specifically, the acoustic attenuation detection device calculates the first fundamental wave attenuation parameter according to the first fundamental wave signal amplitude, the second fundamental wave signal amplitude, and the depth difference.

[0098] Among them, the first fundamental wave attenuation parameter is a parameter used to characterize the attenuation relationship of the ultrasonic wave at the current frequency with depth, and its unit can be dB / cm or dB / m, etc., which is specifically selected according to the actual situation, and the embodiment of the present invention does not make specific limitations.

[0099] In the embodiment of the present invention, the fundamental wave acoustic attenuation related parameter can be the difference in fundamental wave acoustic intensity parameters. Specifically, the acoustic attenuation detection device calculates the difference in fundamental wave acoustic intensity parameters according to the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter.

[0100] In the embodiment of the present invention, the fundamental wave acoustic attenuation related parameter can be the ratio of fundamental wave acoustic intensity parameters. Specifically, the acoustic attenuation detection device calculates the ratio of fundamental wave acoustic intensity parameters according to the first fundamental wave acoustic intensity parameter and the second fundamental wave acoustic intensity parameter.

[0101] In one embodiment, multiple fundamental acoustic intensity parameters can be fitted to obtain a curve showing the change of the fundamental acoustic intensity parameter with depth. Then, based on this curve (for example, when the fundamental acoustic intensity parameter is in dB, the fitted curve may be a straight line; when the fundamental acoustic intensity parameter is in units of signal amplitude, the fitted curve may be an exponential curve; and so on. The fitted curve reflects the change of the fundamental acoustic intensity parameter with depth), the fundamental acoustic attenuation parameter can be calculated according to actual needs. For example, the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter can be fitted to obtain the fundamental acoustic attenuation parameter.

[0102] S106. Calculate the harmonic sound attenuation related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

[0103] After the sound attenuation detection device obtains the first harmonic sound intensity parameter at the first preset depth and the second harmonic sound intensity parameter at the second preset depth using the harmonic signal, the sound attenuation detection device calculates the harmonic sound attenuation related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

[0104] In this embodiment of the invention, the harmonic sound attenuation related parameter can be the first harmonic sound attenuation coefficient. The sound attenuation detection device calculates the first harmonic sound attenuation coefficient based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency.

[0105] For harmonic signals, when ultrasonic waves are sent from the ultrasonic probe to the target object, harmonic signals are generated when the waves propagate to a preset depth D in the target tissue. The harmonic signals then return from the preset depth D to the ultrasonic probe, resulting in the harmonic signals of the ultrasonic echo. Therefore, the frequency point corresponding to the first propagation distance from the ultrasonic probe to the preset depth D is the transmission frequency point, which is also the fundamental frequency point. The frequency point corresponding to the second propagation distance from the preset depth D back to the ultrasonic probe is the harmonic frequency point. Thus, taking the signal amplitude converted to dB as an example, the calculation formula for the first harmonic sound attenuation coefficient is derived as formula (2).

[0106] First harmonic attenuation coefficient = (depth2 harmonic signal amplitude - depth1 harmonic signal amplitude) / (3 * (depth2 - depth1)) / FC (2)

[0107] The specific derivation process is as follows: the difference between the signal amplitude at the initial position and the signal amplitude at the preset depth D is given by formula (3):

[0108] Initial position harmonic signal amplitude - D position harmonic signal amplitude = sound attenuation coefficient × D × FC + sound attenuation coefficient × D × FC × 2 (3)

[0109] Therefore, by transforming formula (3), the sound attenuation coefficient is obtained as formula (4):

[0110] Sound attenuation coefficient = (amplitude of harmonic signal at initial position - amplitude of harmonic signal at position D) / (3 × D) / FC (4)

[0111] Thus, the sound attenuation coefficients applied to the first preset depth and the second preset depth are obtained as shown in formula (2).

[0112] In one embodiment, the harmonic sound attenuation related parameter can be the difference between harmonic sound intensity parameters. Specifically, the sound attenuation detection device calculates the difference between harmonic sound intensity parameters based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

[0113] In one embodiment, the harmonic sound attenuation related parameter can be the ratio of harmonic sound intensity parameters. Specifically, the sound attenuation detection device calculates the ratio of harmonic sound intensity parameters based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

[0114] In one embodiment, multiple harmonic sound intensity parameters can be fitted to obtain a curve showing the variation of harmonic sound intensity parameters with depth. Then, based on this curve (for example, when the harmonic sound intensity parameters are in dB, the fitted curve may be a straight line; when the harmonic sound intensity parameters are in units of signal amplitude, the fitted curve may be an exponential curve; and so on. The fitted curve reflects the variation of the basic sound intensity parameters with depth), the harmonic sound attenuation parameters can be calculated according to actual needs. For example, the first harmonic sound intensity parameter and the second harmonic sound intensity parameter can be fitted to obtain the harmonic sound attenuation parameters.

[0115] S107. Using the fundamental acoustic attenuation correlation parameters and harmonic acoustic attenuation correlation parameters, determine the attenuation characteristics of the target tissue.

[0116] After the acoustic attenuation detection device calculates the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters, the device uses these parameters to determine the attenuation characteristics of the target tissue.

[0117] In this embodiment of the invention, the acoustic attenuation detection device calculates the ratio or mean of the parameters between the fundamental acoustic attenuation parameters and the harmonic acoustic attenuation parameters, and uses the ratio or mean of the parameters to determine the attenuation characteristics of the target tissue.

[0118] In this embodiment of the invention, the sound attenuation detection device displays fundamental sound attenuation related parameters and harmonic sound attenuation related parameters, so that medical personnel can use these parameters to detect the nonlinearity of the sound attenuation of a target object as the frequency changes.

[0119] In this embodiment of the invention, the acoustic attenuation detection device can also emit ultrasonic waves at at least one preset transmission frequency point and acquire at least one fundamental acoustic attenuation related parameter and at least one harmonic acoustic attenuation related parameter corresponding to the at least one preset transmission frequency point; then, the acoustic attenuation detection device combines at least one fundamental acoustic attenuation related parameter and at least one harmonic acoustic attenuation related parameter to obtain multi-frequency acoustic attenuation related parameters; and use the multi-frequency acoustic attenuation related parameters to determine the attenuation characteristics of the target tissue.

[0120] Specifically, the sound attenuation detection device can use at least one fundamental sound attenuation related parameter and at least one harmonic sound attenuation related parameter to obtain parameter ratios, parameter differences, or cluster the parameters to obtain multi-frequency sound attenuation related parameters. The specific selection is based on the actual situation, and the embodiments of the present invention do not impose specific limitations.

[0121] In this embodiment of the invention, when calculating the fundamental sound attenuation correlation parameters and harmonic sound attenuation correlation parameters, the sound attenuation detection device can also perform conventional image processing procedures. These conventional image processing procedures include commonly used imaging techniques such as B-mode imaging, color Doppler ultrasound imaging, and elastography, encompassing various general steps such as beamforming, gain compensation, and quadrature demodulation. Of course, the sound attenuation detection device may also exclude conventional image processing and only perform sound attenuation correlation processing; the specific choice depends on the actual situation, and this embodiment of the invention does not impose specific limitations.

[0122] For example, such as Figure 5 The diagram shown is a system framework diagram of the sound attenuation detection device used in an embodiment of the present invention, including a probe, a scanning control module, a transmitting / receiving module, a conventional image processing module, a fundamental sound attenuation calculation module, a harmonic sound attenuation calculation module, and a display module.

[0123] Understandably, after the acoustic attenuation detection device receives the ultrasonic echo from the target tissue, it extracts the fundamental and harmonic signals from the ultrasonic echo signal and generates fundamental acoustic attenuation parameters based on the fundamental signal; it also generates harmonic acoustic attenuation parameters based on the harmonic signals. Subsequently, the acoustic attenuation detection device determines the attenuation characteristics of the target tissue based on the fundamental and harmonic acoustic attenuation parameters. It can utilize different frequency components in the ultrasonic echo to jointly describe the attenuation characteristics of the entire target tissue, thereby improving the accuracy of acoustic attenuation detection.

[0124] This invention provides a method for detecting sound attenuation, such as... Figure 6 As shown, the method may include:

[0125] S201, Receive ultrasound echoes from the target tissue.

[0126] Here, the description of S201 in this embodiment of the invention is the same as that of S101, and will not be repeated here.

[0127] S202. Extract the fundamental wave signal and harmonic signal from the ultrasonic echo.

[0128] Here, the description of S202 in this embodiment of the invention is the same as that of S102, and will not be repeated here.

[0129] S203. Calculate the fundamental acoustic attenuation parameters using the fundamental signal.

[0130] In this embodiment of the invention, the fundamental sound attenuation related parameters include: a first fundamental sound attenuation coefficient, a first fundamental sound attenuation parameter, a fundamental sound intensity parameter difference, and a fundamental sound intensity parameter ratio. The specific parameters are selected according to the actual situation, and this embodiment of the invention does not impose any specific limitations.

[0131] In this embodiment of the invention, the first fundamental acoustic attenuation coefficient is calculated based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, the depth difference, and the transmission frequency. The first fundamental acoustic intensity parameter is the acoustic intensity parameter of the fundamental signal at a first preset depth, the second fundamental acoustic intensity parameter is the acoustic intensity parameter of the fundamental signal at a second preset depth, and the depth difference is the difference between the first preset depth and the second preset depth. Taking the acoustic intensity parameter as the signal amplitude converted to dB as an example, the specific details can be shown in the aforementioned formula (1).

[0132] In this embodiment of the invention, the first fundamental attenuation parameter is calculated based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, and the depth difference. Specifically, taking the acoustic intensity parameter as the signal amplitude converted to dB as an example, it can be calculated as shown in formula (5).

[0133] First fundamental frequency attenuation parameter = (depth2 fundamental frequency signal amplitude – depth1 fundamental frequency signal amplitude) / (2 * (depth2 - depth1)) (5)

[0134] In this embodiment of the invention, the difference in fundamental acoustic intensity parameters is calculated based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, specifically as shown in formula (6).

[0135] The difference in fundamental acoustic intensity parameter = depth2 fundamental acoustic intensity parameter – depth1 fundamental acoustic intensity parameter (6)

[0136] In this embodiment of the invention, the ratio of the fundamental acoustic intensity parameter is calculated based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, specifically as shown in formula (7).

[0137] The ratio of fundamental acoustic intensity parameters = depth2 fundamental acoustic intensity parameters / depth1 fundamental acoustic intensity parameters (7)

[0138] S204. Calculate the relevant parameters of harmonic sound attenuation using harmonic signals.

[0139] In this embodiment of the invention, the harmonic sound attenuation related parameters include: the first harmonic sound attenuation coefficient, the first harmonic attenuation parameter, the difference in harmonic sound intensity parameters, and the ratio of harmonic sound intensity parameters. The specific parameters are selected according to the actual situation, and this embodiment of the invention does not impose any specific limitations.

[0140] In this embodiment of the invention, the first harmonic sound attenuation coefficient is calculated based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency. The first harmonic sound intensity parameter is the sound intensity parameter of the harmonic signal at a first preset depth, the second harmonic sound intensity parameter is the sound intensity parameter of the harmonic signal at a second preset depth, and the depth difference is the difference between the first preset depth and the second preset depth. Taking the sound intensity parameter as the signal amplitude converted to dB as an example, it can be specifically shown in the aforementioned formula (2).

[0141] In this embodiment of the invention, the first harmonic attenuation parameter is calculated based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference, specifically as shown in formula (8).

[0142] First harmonic attenuation coefficient = (depth2 harmonic intensity parameter - depth1 harmonic intensity parameter) / (3 * (depth2 - depth1)) (8)

[0143] In this embodiment of the invention, the difference in harmonic sound intensity parameters is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, specifically as shown in formula (9).

[0144] Harmonic sound intensity parameter difference = depth2 harmonic sound intensity parameter – depth1 harmonic sound intensity parameter (9)

[0145] In this embodiment of the invention, the ratio of harmonic sound intensity parameters is calculated based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, specifically as shown in formula (10).

[0146] Harmonic sound intensity parameter ratio = depth2 harmonic sound intensity parameter / depth1 harmonic sound intensity parameter (10)

[0147] It should be noted that S203 and S204 are two parallel steps following S202, and the specific selection should be made according to the actual situation. This embodiment of the invention does not impose any specific limitations.

[0148] S205. Using the fundamental acoustic attenuation correlation parameters and harmonic acoustic attenuation correlation parameters, determine the attenuation characteristics of the target tissue.

[0149] Here, the description of S205 in this embodiment of the invention is the same as that of S107, and will not be repeated here.

[0150] Understandably, after the acoustic attenuation detection device receives the ultrasonic echo from the target tissue, it extracts the fundamental and harmonic signals from the ultrasonic echo signal and generates fundamental acoustic attenuation parameters based on the fundamental signal; it also generates harmonic acoustic attenuation parameters based on the harmonic signals. Subsequently, the acoustic attenuation detection device determines the attenuation characteristics of the target tissue based on the fundamental and harmonic acoustic attenuation parameters. It can utilize different frequency components in the ultrasonic echo to jointly describe the attenuation characteristics of the entire target tissue, thereby improving the accuracy of acoustic attenuation detection.

[0151] Those skilled in the art will understand that embodiments of the present invention can be provided as methods, servers, or computer program products. Therefore, the present invention can take the form of hardware embodiments, software embodiments, or embodiments combining software and hardware aspects. Furthermore, the present invention can take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage and optical storage) containing computer-usable program code.

[0152] This invention is described with reference to flowchart illustrations and / or block diagrams of methods, apparatus (servers), and computer program products according to embodiments of the invention. It will be understood that each block of the flowchart illustrations and / or block diagrams, and combinations of blocks in the flowchart illustrations and / or block diagrams, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, special-purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, generate instructions for implementing the flowchart illustrations and / or block diagrams. Figure 1 One or more processes and / or boxes Figure 1 A device that provides the functions specified in one or more boxes.

[0153] These computer program instructions may also be stored in a computer-readable storage medium that can direct a computer or other programmable data processing device to function in a particular manner, such that the instructions stored in the computer-readable storage medium produce an article of manufacture including instruction means, which are implemented in a process Figure 1 One or more processes and / or boxes Figure 1 The function specified in one or more boxes.

[0154] These computer program instructions may also be loaded onto a computer or other programmable data processing equipment to cause a series of operational steps to be performed on the computer or other programmable equipment to produce a computer-implemented process, thereby providing instructions that execute on the computer or other programmable equipment for implementing the process. Figure 1 One or more processes and / or boxes Figure 1 The steps of the function specified in one or more boxes.

[0155] The above description is merely a preferred embodiment of the present invention and is not intended to limit the scope of protection of the present invention.

Claims

1. A method for detecting sound attenuation, characterized in that, The method includes: Receive ultrasound echoes from the target tissue; Extract the fundamental and harmonic signals from the ultrasonic echo; The fundamental wave signal is used to obtain the first fundamental wave acoustic intensity parameter at a first preset depth and the second fundamental wave acoustic intensity parameter at a second preset depth. The first harmonic sound intensity parameter at the first preset depth and the second harmonic sound intensity parameter at the second preset depth are obtained using the harmonic signal. The fundamental acoustic attenuation related parameters are calculated using the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter. Harmonic sound attenuation related parameters are calculated using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter; The attenuation characteristics of the target tissue are determined using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters.

2. The method according to claim 1, characterized in that, The calculation of fundamental sound attenuation related parameters using the first fundamental sound intensity parameter and the second fundamental sound intensity parameter includes: Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, the depth difference, and the transmission frequency, a first fundamental acoustic attenuation coefficient is calculated, and the first fundamental acoustic attenuation coefficient is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, and the depth difference, a first fundamental attenuation parameter is calculated, and the first fundamental attenuation parameter is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the difference in the fundamental acoustic intensity parameter is calculated, and the difference in the fundamental acoustic intensity parameter is determined as the fundamental acoustic attenuation related parameter; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the ratio of the fundamental acoustic intensity parameters is calculated, and the ratio of the fundamental acoustic intensity parameters is determined as the fundamental acoustic attenuation related parameter; or The fundamental acoustic intensity parameters are fitted to the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter to obtain the fundamental acoustic attenuation related parameters.

3. The method according to claim 1, characterized in that, The calculation of harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, a first harmonic sound attenuation coefficient is calculated, and the first harmonic sound attenuation coefficient is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference, the first harmonic attenuation parameter is calculated, and the first harmonic attenuation parameter is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the difference in harmonic sound intensity parameters is calculated, and the difference in harmonic sound intensity parameters is determined as the harmonic sound attenuation related parameter; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, calculate the ratio of the harmonic sound intensity parameters, and determine the ratio of the harmonic sound intensity parameters as the harmonic sound attenuation related parameter; or The first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameters.

4. The method according to any one of claims 1 to 3, characterized in that, The step of determining the attenuation characteristics of the target tissue using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters includes: Calculate the parameter ratio or mean value between the fundamental sound attenuation related parameter and the harmonic sound attenuation related parameter, and use the parameter ratio or the mean value to determine the attenuation characteristics of the target tissue.

5. The method according to any one of claims 1 to 3, characterized in that, The fundamental acoustic attenuation related parameters are calculated using the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter. After calculating the harmonic attenuation related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the method further includes: Display the fundamental acoustic attenuation related parameters and / or the harmonic acoustic attenuation related parameters.

6. A method for detecting sound attenuation, characterized in that, The method includes: Receive the first ultrasound echo from the target tissue; Extract the fundamental wave signal from the first ultrasonic echo; Receive the second ultrasound echo from the target tissue; Harmonic signals are extracted from the second ultrasonic echo; The fundamental wave signal is used to obtain the first fundamental wave acoustic intensity parameter at a first preset depth and the second fundamental wave acoustic intensity parameter at a second preset depth. The first harmonic sound intensity parameter at the first preset depth and the second harmonic sound intensity parameter at the second preset depth are obtained using the harmonic signal. The fundamental acoustic attenuation related parameters are calculated using the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter. Harmonic sound attenuation related parameters are calculated using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter; The attenuation characteristics of the target tissue are determined using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters.

7. The method according to claim 6, characterized in that, The calculation of fundamental sound attenuation related parameters using the first fundamental sound intensity parameter and the second fundamental sound intensity parameter includes: Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, the depth difference, and the transmission frequency, a first fundamental acoustic attenuation coefficient is calculated, and the first fundamental acoustic attenuation coefficient is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, and the depth difference, a first fundamental attenuation parameter is calculated, and the first fundamental attenuation parameter is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the difference in the fundamental acoustic intensity parameter is calculated, and the difference in the fundamental acoustic intensity parameter is determined as the fundamental acoustic attenuation related parameter; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the ratio of the fundamental acoustic intensity parameters is calculated, and the ratio of the fundamental acoustic intensity parameters is determined as the fundamental acoustic attenuation related parameter; or The fundamental acoustic intensity parameters are fitted to the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter to obtain the fundamental acoustic attenuation related parameters.

8. The method according to claim 6, characterized in that, The calculation of harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, a first harmonic sound attenuation coefficient is calculated, and the first harmonic sound attenuation coefficient is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference, the first harmonic attenuation parameter is calculated, and the first harmonic attenuation parameter is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the difference in harmonic sound intensity parameters is calculated, and the difference in harmonic sound intensity parameters is determined as the harmonic sound attenuation related parameter; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, calculate the ratio of the harmonic sound intensity parameters, and determine the ratio of the harmonic sound intensity parameters as the harmonic sound attenuation related parameter; or The first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameters.

9. The method according to any one of claims 6 to 8, characterized in that, The step of determining the attenuation characteristics of the target tissue using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters includes: Calculate the parameter ratio or mean value between the fundamental sound attenuation related parameter and the harmonic sound attenuation related parameter, and use the parameter ratio or the mean value to determine the attenuation characteristics of the target tissue.

10. A method for detecting sound attenuation, characterized in that, The method includes: The first ultrasonic wave is emitted at the first frequency towards the target tissue; The echo of the first ultrasound wave is received from the target tissue to obtain the first ultrasound echo; A second ultrasonic wave is emitted at a second frequency towards the target tissue; The echo of the second ultrasound is received from the target tissue to obtain the second ultrasound echo; Extract the first fundamental wave signal and the first harmonic wave signal from the first ultrasonic echo; Extract the second fundamental wave signal and the second harmonic wave signal from the second ultrasonic echo; Calculate the fundamental acoustic attenuation parameters based on the first fundamental signal and the second fundamental signal; Calculate the harmonic sound attenuation related parameters based on the first harmonic signal and the second harmonic signal; The attenuation characteristics of the target tissue are determined using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters.

11. The method according to claim 10, characterized in that, The fundamental acoustic attenuation related parameters are calculated based on the first fundamental signal and the second fundamental signal, including: The first fundamental acoustic intensity parameter at a first preset depth is obtained based on the first fundamental signal; The second fundamental acoustic intensity parameter at the second preset depth is obtained based on the second fundamental signal; The fundamental acoustic attenuation parameters are calculated using the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter.

12. The method according to claim 10, characterized in that, The parameters related to harmonic sound attenuation calculated based on the first harmonic signal and the second harmonic signal include: The first harmonic sound intensity parameter at the first preset depth is obtained based on the first harmonic signal; The second harmonic sound intensity parameter at the second preset depth is obtained based on the second harmonic signal; Harmonic attenuation parameters are calculated using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter.

13. The method according to claim 11, characterized in that, The calculation of fundamental sound attenuation related parameters using the first fundamental sound intensity parameter and the second fundamental sound intensity parameter includes: Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, the depth difference, and the transmission frequency, a first fundamental acoustic attenuation coefficient is calculated, and the first fundamental acoustic attenuation coefficient is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, and the depth difference, a first fundamental attenuation parameter is calculated, and the first fundamental attenuation parameter is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the difference in the fundamental acoustic intensity parameter is calculated, and the difference in the fundamental acoustic intensity parameter is determined as the fundamental acoustic attenuation related parameter; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the ratio of the fundamental acoustic intensity parameters is calculated, and the ratio of the fundamental acoustic intensity parameters is determined as the fundamental acoustic attenuation related parameter; or The fundamental acoustic intensity parameters are fitted to the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter to obtain the fundamental acoustic attenuation related parameters.

14. The method according to claim 12, characterized in that, The calculation of harmonic attenuation-related parameters using the first harmonic sound intensity parameter and the second harmonic sound intensity parameter includes: Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, a first harmonic sound attenuation coefficient is calculated, and the first harmonic sound attenuation coefficient is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference, the first harmonic attenuation parameter is calculated, and the first harmonic attenuation parameter is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the difference in harmonic sound intensity parameters is calculated, and the difference in harmonic sound intensity parameters is determined as the harmonic sound attenuation related parameter; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, calculate the ratio of the harmonic sound intensity parameters, and determine the ratio of the harmonic sound intensity parameters as the harmonic sound attenuation related parameter; or The first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameters.

15. The method according to any one of claims 10 to 14, characterized in that, The step of determining the attenuation characteristics of the target tissue using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters includes: Calculate the parameter ratio or mean value between the fundamental sound attenuation related parameter and the harmonic sound attenuation related parameter, and use the parameter ratio or the mean value to determine the attenuation characteristics of the target tissue.

16. A method for detecting sound attenuation, characterized in that, The method includes: Receive ultrasound echoes from the target tissue; The fundamental acoustic intensity parameters at at least two preset depths are obtained using the ultrasonic echo; The ultrasonic echo is used to obtain harmonic sound intensity parameters at at least two preset depths; The fundamental acoustic attenuation related parameters are calculated using the fundamental acoustic intensity parameters at the at least two preset depths; Harmonic attenuation parameters are calculated using the harmonic sound intensity parameters at the at least two preset depths. The attenuation characteristics of the target tissue are determined using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters.

17. The method as described in any one of claims 1, 6, or 16, characterized in that, The fundamental wave acoustic intensity parameter is the fundamental wave signal energy, fundamental wave signal intensity, or fundamental wave signal amplitude, and the harmonic acoustic intensity parameter is the harmonic signal energy, harmonic signal intensity, or harmonic signal amplitude.

18. A method for detecting sound attenuation, characterized in that, The method includes: Receive ultrasound echoes from the target tissue; Extract the fundamental and harmonic signals from the ultrasonic echo; The fundamental wave signal is used to calculate the fundamental wave acoustic attenuation related parameters; The harmonic attenuation parameters are calculated using the harmonic signal. The attenuation characteristics of the target tissue are determined using the fundamental acoustic attenuation correlation parameters and the harmonic acoustic attenuation correlation parameters.

19. A sound attenuation detection device, characterized in that, The sound attenuation detection device includes: Ultrasonic probe; A transmitting circuit that excites the ultrasound probe to emit ultrasound waves toward the target tissue; A receiving circuit that receives ultrasound echoes returned from the target tissue via the ultrasound probe; A processor that processes the ultrasound echo signal to obtain an ultrasound image of the target tissue; A display showing the ultrasound image; Specifically, the processor performs the following steps: extracting fundamental and harmonic signals from the ultrasonic echo; using the fundamental signal to obtain a first fundamental acoustic intensity parameter at a first preset depth and a second fundamental acoustic intensity parameter at a second preset depth; using the harmonic signal to obtain the first harmonic acoustic intensity parameter at the first preset depth and the second harmonic acoustic intensity parameter at the second preset depth; using the first and second fundamental acoustic intensity parameters to calculate fundamental acoustic attenuation-related parameters; using the first and second harmonic acoustic intensity parameters to calculate harmonic acoustic attenuation-related parameters; and using the fundamental acoustic attenuation-related parameters and the harmonic acoustic attenuation-related parameters to determine the attenuation characteristics of the target tissue.

20. The sound attenuation detection device according to claim 19, characterized in that, The processor: Based on the first fundamental acoustic intensity parameter, the second fundamental acoustic intensity parameter, the depth difference, and the transmission frequency, a first fundamental acoustic attenuation coefficient is calculated, and the first fundamental acoustic attenuation coefficient is determined as the fundamental acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first fundamental wave acoustic intensity parameter, the second fundamental wave acoustic intensity parameter, and the depth difference, a first fundamental wave attenuation parameter is calculated, and the first fundamental wave attenuation parameter is determined as the fundamental wave acoustic attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the difference in fundamental acoustic intensity parameter is calculated, and the difference in fundamental acoustic intensity parameter is determined as the fundamental acoustic attenuation related parameter; or Based on the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter, the ratio of the fundamental acoustic intensity parameters is calculated, and the ratio of the fundamental acoustic intensity parameters is determined as the fundamental acoustic attenuation related parameter; or The fundamental acoustic intensity parameters are fitted to the first fundamental acoustic intensity parameter and the second fundamental acoustic intensity parameter to obtain the fundamental acoustic attenuation related parameters.

21. The sound attenuation detection device according to claim 19 or 20, characterized in that, The processor: Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, the depth difference, and the transmission frequency, a first harmonic sound attenuation coefficient is calculated, and the first harmonic sound attenuation coefficient is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth, and the transmission frequency is the frequency at which ultrasonic waves are emitted toward the target tissue; or Based on the first harmonic sound intensity parameter, the second harmonic sound intensity parameter, and the depth difference, the first harmonic attenuation parameter is calculated, and the first harmonic attenuation parameter is determined as the harmonic sound attenuation related parameter, wherein the depth difference is the depth difference between the first preset depth and the second preset depth; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the difference in harmonic sound intensity parameters is calculated, and the difference in harmonic sound intensity parameters is determined as the harmonic sound attenuation related parameter; or Based on the first harmonic sound intensity parameter and the second harmonic sound intensity parameter, the ratio of the harmonic sound intensity parameters is calculated, and the ratio of the harmonic sound intensity parameters is determined as the harmonic sound attenuation related parameter; or The first harmonic sound intensity parameter and the second harmonic sound intensity parameter are fitted to obtain the harmonic sound attenuation related parameters.

22. The acoustic attenuation detection device according to any one of claims 19 or 20, characterized in that, The processor is further configured to calculate the parameter ratio or the mean value between the fundamental sound attenuation related parameters and the harmonic sound attenuation related parameters, and to use the parameter ratio or the mean value to determine the attenuation characteristics of the target tissue.

23. The acoustic attenuation detection device according to any one of claims 19 or 20, characterized in that, The display is also used to display the fundamental sound attenuation related parameters and / or the harmonic sound attenuation related parameters.

24. The sound attenuation detection device according to claim 19, characterized in that, The transmitting circuit is also used to send ultrasound waves at at least one preset transmitting frequency point to the target tissue using at least one ultrasound probe.

25. The sound attenuation detection device according to claim 24, characterized in that, The receiving circuit is further configured to receive an ultrasonic echo from the target tissue at least one preset transmission frequency point using the at least one ultrasonic probe, wherein one of the at least one ultrasonic probes receives an ultrasonic echo from a preset transmission frequency point.

26. The sound attenuation detection device according to claim 24, characterized in that, The processor is further configured to acquire at least one fundamental acoustic attenuation related parameter and at least one harmonic acoustic attenuation related parameter corresponding to the at least one preset transmission frequency point; By combining the at least one fundamental sound attenuation correlation parameter and the at least one harmonic sound attenuation correlation parameter, multi-frequency sound attenuation correlation parameters are obtained; The attenuation characteristics of the target tissue are determined using the multi-frequency acoustic attenuation correlation parameters.

27. The sound attenuation detection device according to claim 24, characterized in that, The transmitting circuit is also used to send an ultrasonic wave at a first preset transmission frequency point to the target tissue using the at least one ultrasonic probe, wherein the first preset transmission frequency point is the same as the fundamental frequency of the fundamental wave signal.

28. The sound attenuation detection device according to claim 27, characterized in that, The receiving circuit is further configured to receive the fundamental wave signal from the target tissue using a first ultrasound probe, wherein the first ultrasound probe is any one of the at least one ultrasound probes; and to receive the harmonic signal from the target tissue using a second ultrasound probe, wherein the second ultrasound probe is an ultrasound probe other than the first ultrasound probe among the at least one ultrasound probes.

29. A storage medium, characterized in that, The storage medium stores a computer program that can be executed by a processor to implement the acoustic attenuation detection method according to any one of claims 1-18.