Inspection device, PTP packaging machine and method for manufacturing PTP sheet

Abstract

Provided are an inspection device, a PTP packaging machine, and a method for manufacturing a PTP sheet, which can improve the inspection accuracy related to the inspection of abnormal product mixing using spectral analysis. The inspection device (22) includes: an illumination device (52) that can irradiate near-infrared light to tablets (5) filled in a bag portion (2) of a transported container film (3); and an imaging device (53) that can spectrally reflect the near-infrared light reflected from the tablets (5), and photograph the spectral image of the reflected light. Based on the spectral image photographed by the imaging device (53), spectral data of multiple points on the tablets (5) are obtained. For the spectral data of the multiple points, an intermediate value is selected for each wavelength. Based on the intermediate value spectral data composed of the intermediate values ​​selected for each wavelength, a predetermined analysis process is performed on the tablets (5), and mixing of different products can be detected.

Description

Technical Field

[0001] The invention relates to an inspection device, a PTP packaging machine and a manufacturing method of a PTP sheet, which are used for inspecting the mixing of different varieties by using spectral analysis. Background Art

[0002] Generally, a PTP sheet is composed of a container film having a pocket filled with an object such as a tablet, and a cover film attached to the container film so as to seal the opening side of the pocket.

[0003] When manufacturing PTP sheets, a different variety mixing inspection is performed to check for the mixing of different varieties. As a method for this inspection, the following method is known: irradiating a target with near-infrared light, splitting its reflected light using a spectrometer, and performing analysis and processing (for example, principal component analysis) based on the spectral data obtained by photographing the target, thereby detecting the mixing of different varieties.

[0004] Generally, when performing analysis based on spectral data, spectral data of multiple points on each object are averaged to calculate average spectral data related to the object, and the type of the object is determined based on the average spectral data (for example, refer to Patent Document 1).

[0005] Alternatively, the center position of each object is detected, and the spectral data of multiple points near the center position are averaged to calculate the average spectral data of the object, and the type of the object is determined based on the average spectral data (for example, refer to Patent Document 2).

[0006] Prior art literature

[0007] Patent Literature

[0008] Patent Document 1: WO2013 / 002291

[0009] Patent Document 2: WO2005 / 038443 Summary of the invention

[0010] Problems to be solved by the invention

[0011] However, in the prior art techniques such as those disclosed in Patent Documents 1 and 2, simply averaging the spectrum data in a predetermined region on the object may fail to obtain appropriate average spectrum data for the object.

[0012] For example, due to the influence of shadows produced by concave portions on the object (such as tablet engravings or dividing lines) or the outer edge of the object, or due to the influence of reflections caused by specular reflections produced by convex portions on the object, there is a risk that even in the case of the same tablet, the data at each coordinate point will deviate greatly and uniformity may not be maintained.

[0013] The present invention is proposed in view of the above situation, and its purpose is to provide an inspection device, a PTP packaging machine and a method for manufacturing a PTP sheet, which can seek to improve the inspection accuracy related to the inspection of different varieties mixed by spectroscopic analysis.

[0014] Technical solutions to solve problems

[0015] Below, for each technical solution suitable for solving the above-mentioned problem, it is described in sections. In addition, according to the needs, the corresponding technical solution is followed by a unique effect.

[0016] Technical solution 1. relates to an inspection device, characterized in that the inspection device comprises:

[0017] an irradiation mechanism capable of irradiating a target object with near-infrared light;

[0018] a spectroscopic mechanism capable of spectroscopically spectroscopically detecting reflected light from the object irradiated with the near-infrared light;

[0019] A camera mechanism capable of photographing a spectroscopic image of the reflected light split by the spectroscopic mechanism;

[0020] a spectral data acquisition mechanism that can acquire spectral data of a plurality of points (a plurality of coordinate positions) on the object based on the spectral image acquired by the imaging mechanism;

[0021] A median value selection mechanism, wherein the median value selection mechanism selects a median value for each wavelength (wavelength range) based on the spectral data of the plurality of points;

[0022] An analyzing means can detect different varieties by performing a predetermined analysis process (for example, principal component analysis) on the object based on the median spectrum data composed of the median values ​​selected for each of the wavelengths.

[0023] According to the above-mentioned technical solution 1, even when there are deviations in the data of multiple coordinate points on an object, the spectral data of the unique points on the object can be excluded through relatively simple calculation processing, and appropriate spectral data (intermediate spectral data) can be obtained when performing spectroscopic analysis on the object.

[0024] Thus, even when there are recesses or projections on the object, for example, the influence of shadows caused by the recesses or reflections caused by the projections can be avoided, and the object can be properly inspected.

[0025] As a result, the inspection accuracy of the mixed product inspection can be significantly improved compared with a method of simply averaging the spectrum data of a plurality of points on the object.

[0026] Technical solution 2. relates to an inspection device, which includes:

[0027] an irradiation mechanism capable of irradiating a target object with near-infrared light;

[0028] a spectroscopic mechanism capable of spectroscopically spectroscopically detecting reflected light from the object irradiated with the near-infrared light;

[0029] A camera mechanism capable of photographing a spectroscopic image of the reflected light split by the spectroscopic mechanism;

[0030] a spectral data acquisition mechanism that can acquire spectral data of a plurality of points (a plurality of coordinate positions) on the object based on the spectral image acquired by the imaging mechanism;

[0031] a representative spectrum selecting means for selecting, from the spectrum data of the plurality of points, spectrum data in which the sum of the brightness values ​​of a predetermined wavelength (wavelength band) or the brightness values ​​of a predetermined wavelength range (a plurality of wavelength band groups) becomes an intermediate value as representative spectrum data representing the object;

[0032] An analysis unit can detect different varieties by performing a predetermined analysis process (for example, principal component analysis) on the object based on the representative spectrum data.

[0033] According to the above technical solution 2, the same effect as the above technical solution 1 is achieved.

[0034] Technical solution 3. relates to a PTP packaging machine for manufacturing the following PTP sheet, in which an object is received in a bag portion formed on a container film, and a cover film is installed in a manner of sealing the bag portion, characterized in that the PTP packaging machine comprises:

[0035] a pocket forming mechanism for forming the pocket on the strip-shaped container film;

[0036] a filling mechanism for filling the object into the bag portion;

[0037] An installation mechanism, which installs the strip-shaped cover film on the container film filled with the object in the bag portion in a manner that closes the bag portion;

[0038] a cutting mechanism (including a punching mechanism for punching in sheet units) for cutting the PTP sheet from a strip-shaped body on which the cover film is attached to the container film; and

[0039] The inspection device described in the above technical solution 1 or 2.

[0040] As in the above technical solution 3, the PTP packaging machine has the inspection device described in the above technical solution 1 or 2, thereby having the advantage of being able to effectively exclude defective products including different varieties in the manufacturing process of the PTP sheet. In addition, the PTP packaging machine can also be formed into the following structure, which includes a discharge mechanism, which discharges the PTP sheet determined as a defective product by the above inspection device.

[0041] In the above technical solution 3, the following solution may be adopted, wherein the inspection device is provided in "a prior step of filling the object into the bag portion by the filling mechanism". In this case, different varieties can be excluded in the prior stage of filling into the bag portion, and the number of PTP sheets constituting defective products can be reduced.

[0042] In addition, the following scheme may be formed, wherein the inspection device is provided in "a subsequent step of filling the bag portion with the object by the filling mechanism and a prior step of installing the cover film by the installing mechanism". In this case, the inspection can be performed without shielding the object, thereby further improving the inspection accuracy.

[0043] In addition, the following scheme can also be formed, wherein the above-mentioned inspection device is set in "a subsequent step of installing the cover film by the installation mechanism and a prior step of cutting the PTP sheet by the separation mechanism". In this case, the inspection can be performed without changing the object, so that the inspection accuracy can be further improved.

[0044] Furthermore, the inspection device may be provided in a subsequent step of cutting the PTP sheet by a cutting mechanism. In this case, it is possible to check whether defective products are mixed in the final stage.

[0045] Technical solution 4. relates to a method for manufacturing a PTP sheet, the method for manufacturing a PTP sheet is used to manufacture the following PTP sheet, in which an object is received in a bag portion formed on a container film, and a cover film is installed in a manner of sealing the bag portion, characterized in that the method for manufacturing the PTP sheet comprises:

[0046] a bag portion forming step, in which the bag portion is formed on the strip-shaped container film;

[0047] a filling step in which the object is filled into the bag portion;

[0048] An installation step, in which the strip-shaped cover film is installed on the container film filled with the object in the bag portion in a manner to close the bag portion;

[0049] a cutting step (including a punching step of punching in sheet units), in which the PTP sheet is cut from a strip body on which the cover film is mounted on the container film;

[0050] an inspection step, in which the mixing of different varieties is inspected;

[0051] The above inspection steps include:

[0052] an irradiation step of irradiating the object with near-infrared light;

[0053] a spectroscopic step of spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically on reflected light reflected from the object irradiated with the near-infrared light;

[0054] an imaging step (exposure step), in which a spectroscopic image of the spectroscopic reflected light is photographed;

[0055] a spectral data obtaining step, in which spectral data of a plurality of points on the object are obtained based on the spectral image;

[0056] an intermediate value selection step, in which an intermediate value is selected for each wavelength with respect to the spectral data of the plurality of points;

[0057] An analysis step in which a different variety is detected by performing a predetermined analysis process (for example, principal component analysis) on the object based on the intermediate value spectrum data composed of the intermediate values ​​selected at the wavelengths.

[0058] According to the above technical solution 4, the same effect as the above technical solution 3 is achieved.

[0059] Technical solution 5. relates to a method for manufacturing a PTP sheet, the method for manufacturing a PTP sheet is used to manufacture the following PTP sheet, in which an object is received in a bag portion formed on a container film, and a cover film is installed in a manner of sealing the bag portion, characterized in that the method for manufacturing the PTP sheet comprises:

[0060] a bag portion forming step, in which the bag portion is formed on the strip-shaped container film;

[0061] a filling step in which the object is filled into the bag portion;

[0062] An installation step, in which the strip-shaped cover film is installed on the container film filled with the object in the bag portion in a manner to close the bag portion;

[0063] a cutting step (including a punching step of punching in sheet units), in which the PTP sheet is cut from a strip-shaped body (strip-shaped PTP sheet) on which the cover film is mounted on the container film;

[0064] an inspection step, in which the mixing of different varieties is checked;

[0065] The above inspection steps include:

[0066] an irradiation step of irradiating the object with near-infrared light;

[0067] a spectroscopic step of spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically on reflected light reflected from the object irradiated with the near-infrared light;

[0068] an imaging step (exposure step), in which a spectroscopic image of the spectroscopic reflected light is photographed;

[0069] a spectral data obtaining step, in which spectral data of a plurality of points on the object are obtained based on the spectral image;

[0070] a representative spectrum selecting step, in which spectrum data of a brightness value at a predetermined wavelength or a sum of brightness values ​​in a predetermined wavelength range are selected as representative spectrum data representing the object from the spectrum data of the plurality of points;

[0071] An analysis step in which different varieties can be detected by performing a predetermined analysis process (for example, principal component analysis) on the object based on the spectral data.

[0072] According to the above technical solution 5, the same effect as the above technical solution 3 is achieved.

[0073] In the above technical solutions 4 and 5, the above inspection step can also be performed in a "step prior to the filling step". In this case, different varieties can be excluded in the previous stage of filling in the bag part, and the number of PTP sheets constituting defective products can be reduced.

[0074] In addition, the inspection step may be performed in a step after the filling step and before the mounting step. In this case, the inspection can be performed without shielding the object, thereby improving the inspection accuracy.

[0075] In addition, it is also possible to form a scheme in which the above-mentioned inspection step is performed in "a step after the mounting step and a step before the separation step." In this case, the inspection can be performed without changing the object, thereby improving the inspection accuracy.

[0076] Alternatively, the inspection step may be performed in a "step after the separation step." In this case, it is possible to confirm whether defective products are mixed in the final stage. BRIEF DESCRIPTION OF THE DRAWINGS

[0077] Figure 1 (a) is a stereogram showing a PTP sheet, Figure 1 (b) is a stereogram showing a PTP film;

[0078] Figure 2 It is a partial enlarged cross-sectional view of the bag portion of the PTP sheet;

[0079] Figure 3 It is a schematic diagram showing the basic structure of the PTP packaging machine;

[0080] Figure 4 A block diagram showing the electrical structure of the inspection device;

[0081] Figure 5 A perspective view schematically showing the configuration structure of the inspection device;

[0082] Figure 6 A schematic diagram showing a schematic structure of a camera device;

[0083] Figure 7 is a flow chart showing the process of obtaining spectral data;

[0084] Figure 8 is a schematic diagram showing a spectroscopic spectrum projected onto an imaging element;

[0085] Fig. 9 A flowchart showing the inspection process;

[0086] Fig.10 is an explanatory diagram for explaining the relationship between the camera range in the transmission direction and the spectral image;

[0087] Fig.11 is a schematic diagram representing a spectral image;

[0088] Fig.12is a schematic diagram showing an example of a plurality of coordinate points for obtaining spectral data on a tablet;

[0089] Fig.13 is a table showing an example of spectral data obtained at a plurality of coordinate points on a tablet;

[0090] Fig.14 To pass Fig.13 Graphs are plotted for various values ​​shown. DETAILED DESCRIPTION

[0091] An embodiment will be described below with reference to the accompanying drawings. First, the structure of the PTP sheet will be described in detail.

[0092] picture Figure 1 , Figure 2 As shown, the PTP sheet 1 includes a container film 3 having a plurality of pockets 2 and a cover film 4 attached to the container film 3 so as to close the pockets 2 .

[0093] The container film 3 of this embodiment is formed of a transparent thermoplastic resin material such as PP (polypropylene) or PVC (polyvinyl chloride) and has light transmittance. On the other hand, the cover film 4 is made of an opaque material (e.g., aluminum foil) having a sealant such as polypropylene resin on the surface.

[0094] The PTP sheet 1 is substantially rectangular in plan view. On the PTP sheet 1, a row of pockets formed by five pockets 2 arranged in the longitudinal direction thereof is formed in two rows in the direction of the shorter dimension thereof. That is, a total of ten pockets 2 are formed. In each pocket 2, a tablet 5 is received as an object one at a time.

[0095] picture Figure 2 As shown in the figure, the tablet 5 of this embodiment is a plain tablet in a circular disc shape when viewed from above, and has a structure having a side surface 5A, a flat surface 5B sandwiching the side surface 5A, and a back surface 5C. In addition, in this embodiment, the tablet 5 is received in such a manner that the surface 5B faces the cover film 4 side and the back surface 5C faces the bottom wall (top wall) side of the bag portion 2.

[0096] In addition, in the tablet 5 , a tapered portion 5D is formed by chamfering the boundary between the side surface 5A and the front surface 5B, and a tapered portion 5E is formed by chamfering the boundary between the side surface 5A and the back surface 5C.

[0097] Furthermore, a groove-shaped dividing line 5F extending linearly through the center of the surface 5B is engraved on the surface 5B of the tablet 5. The dividing line 5F is engraved only on the surface 5B and not on the back surface 5C.

[0098] PTP chip 1 (refer to Figure 1 (a)) is manufactured by the following method: a strip-shaped PTP film 6 (refer to Figure 1 (b)) is stamped in sheet form.

[0099] Next, refer to Figure 3 , the basic structure of the PTP packaging machine 10 for manufacturing the above-mentioned PTP sheet 1 is explained.

[0100] picture Figure 3 As shown, a raw material roll of a strip-shaped container film 3 is wound in a roll shape at the most upstream side of the PTP packaging machine 10. The draw-out end side of the container film 3 wound in a roll shape is guided by a guide roller 13. The container film 3 is hung on an intermittent conveying roller 14 on the downstream side of the guide roller 13. The intermittent conveying roller 14 is connected to a motor that rotates intermittently, and conveys the container film 3 intermittently.

[0101] A heating device 15 and a pocket forming device 16 are sequentially provided between the guide roller 13 and the intermittent conveying roller 14 along the conveying path of the container film 3. In addition, the container film 3 is heated by the heating device 15, and the container film 3 is in a relatively soft state, and a plurality of pockets 2 are formed at predetermined positions of the container film 3 by the pocket forming device 16 (pocket forming step). The heating device 15 and the pocket forming device 16 constitute the pocket forming mechanism of the present embodiment. The pockets 2 are formed during the intervals between the conveying operations of the container film 3 by the intermittent conveying roller 14.

[0102] The container film 3 fed from the intermittent feeding roller 14 is sequentially hung on the tension roller 18, the guide roller 19 and the film receiving roller 20. Since the film receiving roller 20 is connected to a motor that rotates constantly, the container film 3 is continuously fed at a constant speed. The tension roller 18 is in a state of being stretched toward one side of the container film 3 by elastic force, and the container film 3 is prevented from being bent due to the difference in the feeding actions of the intermittent feeding roller 14 and the film receiving roller 20, and the container film 3 is kept in a tensioned state at ordinary times.

[0103] Between the guide roller 19 and the film receiving roller 20, along the conveying path of the container film 3, a tablet filling device 21 and an inspection device 22 are provided in this order.

[0104] The tablet filling device 21 has a function as a filling mechanism that automatically fills the tablets 5 into the bag portion 2. The tablet filling device 21 is synchronized with the conveying action of the container film 3 of the film receiving roller 20, opens the shutter at a predetermined interval, thereby causing the tablets 5 to fall, and fills the tablets 5 into each bag portion 2 with the shutter opening action (filling step).

[0105] The inspection device 22 is a spectroscopic analysis device that performs inspection by spectroscopic analysis, and is used to inspect for mixing of different types. The inspection device 22 will be described in detail later.

[0106] On the other hand, the raw material roll of the belt-shaped cover film 4 is wound in a roll shape on the most upstream side.

[0107] The lead-out end of the rolled cover film 4 is guided to the heating roller 25 via the guide roller 24. The heating roller 25 can be pressed against the film receiving roller 20, and the container film 3 and the cover film 4 are fed between the two rollers 20 and 25.

[0108] In addition, the container film 3 and the cover film 4 are passed between the two rollers 20 and 25 in a heated and pressed state, whereby the cover film 4 is attached to the container film 3 and the bag portion 2 is closed by the cover film 4 (installation step). Thus, the PTP film 6 as a strip-shaped body in which the tablets 5 are filled in each bag portion 2 is manufactured. Fine mesh-shaped convex strips for sealing are formed on the surface of the heating roller 25, and by strongly pressing them, a firm seal is achieved. The film receiving roller 20 and the heating roller 25 constitute the installation mechanism of this embodiment.

[0109] The PTP film 6 fed from the film receiving roller 20 is sequentially mounted on the tensioning roller 27 and the intermittent conveying roller 28. The intermittent conveying roller 28 is connected to a motor that rotates intermittently, thereby intermittently conveying the PTP film 6. The tensioning roller 27 is in a state of stretching toward one side of the PTP film 6 by elastic force, preventing the PTP film 6 from being bent due to the difference in conveying actions between the film receiving roller 20 and the intermittent conveying roller 28, and keeping the PTP film 6 in a tensioned state at ordinary times.

[0110] The PTP film 6 fed from the intermittent conveying roller 28 is sequentially hung on the tension roller 31 and the intermittent conveying roller 32. The intermittent conveying roller 32 is connected to a motor that rotates intermittently, thereby intermittently conveying the PTP film 6. The tension roller 31 is in a state of stretching the PTP film 6 to one side by elastic force, thereby preventing the PTP film 6 from being bent between the intermittent conveying rollers 28 and 32.

[0111] Between the intermittent conveying roller 28 and the tension roller 31, a slit forming device 33 and an imprinting device 34 are sequentially provided along the conveying path of the PTP film 6. The slit forming device 33 has a function of forming a slit for cutting at a predetermined position of the PTP film 6. In addition, the imprinting device 34 has a function of adding an imprint to a predetermined position (e.g., a label portion) of the PTP film 6.

[0112] The PTP film 6 fed from the intermittent conveying roller 32 is sequentially hung on the tension roller 35 and the continuous conveying roller 36 on its downstream side. A sheet punching device 37 is provided between the intermittent conveying roller 32 and the tension roller 35 along the conveying path of the PTP film 6. The sheet punching device 37 has a function as a sheet punching mechanism (separation mechanism) that punches the outer edge of the PTP film 6 according to a unit of the PTP sheet.

[0113] The PTP sheet 1 punched by the sheet punching device 37 is conveyed by the conveyor 39 and temporarily stored in the finished product hopper 40 (cutting step). However, when the PTP sheet 1 is judged as a defective product by the inspection device 22, the defective PTP sheet 1 is not conveyed to the finished product hopper 40, but is discharged separately by a defective sheet discharge mechanism as a discharge mechanism not shown in the figure.

[0114] A cutting device 41 is provided on the downstream side of the continuous conveying roller 36. In addition, the unnecessary film portion 42 constituting the residual material portion (waste portion) remaining in a strip shape after the punching of the sheet punching device 37 is guided to the cutting device 41 after being guided to the tension roller 35 and the continuous conveying roller 36. In addition, the continuous conveying roller 36 is pressed against the driven roller, and the unnecessary film 42 is conveyed while being clamped. The cutting device 41 has a function of cutting the unnecessary film portion 42 according to a specified size and treating it as waste. The waste is stored in the waste hopper 43 and then treated separately.

[0115] In addition, the rollers 14, 20, 28, 31, 32, etc. are located in a positional relationship where the roller surfaces face the bag 2. However, since recesses for receiving the bag 2 are formed on the surfaces of the intermittent conveying rollers 14, etc., the bag 2 is not crushed. In addition, the conveying operation is performed while the bag 2 is received in the recesses of the intermittent conveying rollers 14, etc., thereby reliably performing the intermittent conveying operation and the continuous conveying operation.

[0116] Although not shown in the figure, a stacking device, a conveying device, a packaging device, etc. are sequentially provided on the downstream side of the PTP packaging machine 10. In addition, the scattered PTP sheets 1 received in the finished product hopper 40 are stacked in groups of two, for example, in the stacking device. The stacked body formed by the stacked plurality of PTP sheets 1 is transported to the packaging device while being strapped by the conveying device, and pillow packaging, etc., is performed in the packaging device.

[0117] The basic structure of the PTP packaging machine 10 is as described above, and the structure of the inspection device 22 will be described in detail below with reference to the drawings. Figure 4 is a block diagram showing the electrical structure of the inspection device 22, Figure 5It is a perspective view schematically showing the arrangement structure of the inspection device 22 .

[0118] picture Figure 4 , Figure 5 As shown, the inspection device 22 includes an illumination device 52, an imaging device 53, and a control processing device 54 that performs various controls within the inspection device 22, such as driving control of the illumination device 52 and the imaging device 53, and performs image processing, calculation processing, and the like.

[0119] The lighting device 52 and the imaging device 53 are provided on the opening side of the bag portion 2 of the container film 3. That is, in this embodiment, the different-variety mixing inspection is performed from the opening side of the bag portion 2 of the container film 3 at the previous stage of attaching the cover film 4.

[0120] The lighting device 52 is a known device configured to irradiate near-infrared light, and constitutes the irradiation means in this embodiment. The lighting device 52 is provided to irradiate near-infrared light from obliquely above toward a predetermined area on the container film 3 being continuously transported.

[0121] In the lighting device 52 of this embodiment, a halogen lamp is used as a light source that can emit near-infrared light having a continuous spectrum (for example, near-infrared region with a wavelength of 700 to 2500 nm). Alternatively, a deuterium discharge tube, a tungsten lamp, a xenon lamp, etc. can be used as the light source.

[0122] picture Figure 6 As shown, the imaging device 53 includes an optical lens 61 , a two-dimensional spectrometer 62 as a spectroscopic mechanism, and a camera 63 as an imaging mechanism.

[0123] The optical lens 61 is composed of a plurality of lenses (not shown) and is configured to collimate incident light. The optical axis of the optical lens 61 is set along the vertical direction (Z direction).

[0124] The optical lens 61 is configured so that incident light can be imaged at the position of the slit 62a of the two-dimensional beam splitter 62 described later. In addition, here, for convenience, an example of using a double-sided telecentric lens as the optical lens 61 is shown, but it can also be an image-side telecentric lens.

[0125] The two-dimensional spectrometer 62 is composed of a slit 62a, an incident side lens 62b, a spectrometer 62c, and an exit side lens 62d. The spectrometer 62c is composed of an incident side prism 62ca, a transmission type diffraction grating 62cb, and an exit side prism 62cc.

[0126] Under the conditions of this structure, the light passing through the slit 62a is collimated by the incident side lens 62b, then split by the spectrometer 62c, and is imaged as a two-dimensional spectroscopic image (spectral spectrum image) by the exit side lens 62d on the imaging element 65 of the camera 63 described later.

[0127] The slit 62a is formed as an elongated substantially rectangular (linear) opening, and its opening width direction (shorter dimension direction) is arranged along the film conveying direction (X direction) of the container film 3, and its longer dimension direction is arranged along the film width direction (Y direction) of the container film 3 perpendicular to the above conveying direction. Therefore, the two-dimensional spectroscope 62 separates the incident light along the opening width direction of the slit 62a, that is, the film conveying direction (X direction).

[0128] The camera 63 has an imaging element 65 having a photosensitive surface 65a formed by two-dimensionally arranging a plurality of photosensitive elements (photosensitive parts) 64 in a matrix. In this embodiment, a known CCD area sensor having sufficient sensitivity to a wavelength range of, for example, 900 to 2000 nm in the near-infrared region is used as the imaging element 65.

[0129] Of course, the imaging element is not limited thereto, and other sensors having sensitivity in the near-infrared region may also be used, such as CMOS sensors or MCT (HgCdTe) sensors.

[0130] The field of view area (imaging area) of the imaging device 53 is a linear area extending in the film width direction (Y direction), and is an area including at least the entire area of ​​the container film 3 in the film width direction (see Figure 5 On the other hand, the field of view of the imaging device 53 in the film conveying direction (X direction) constitutes an area corresponding to the width of the slit 62a. That is, it is an area where the light (slit light) passing through the slit 62a is imaged on the photosensitive surface 65a of the imaging element 65.

[0131] Thus, each wavelength component (for example, every 20 nm bandwidth) of the spectral spectrum of the reflected light reflected at each position in the film width direction (Y direction) of the container film 3 is received by each photosensitive element 64 of the imaging element 65. Then, a signal corresponding to the intensity of the light received by each photosensitive element 64 is converted into a digital signal and output from the camera 63 to the control processing device 54. That is, an image signal (spectral image data) of one screen captured by the entire photosensitive surface 65a of the imaging element 65 is output to the control processing device 54.

[0132] The control processing device 54 includes a CPU and an input / output interface 71 (hereinafter referred to as "CPU, etc. 71") for controlling the entirety of the inspection device 22, an input device 72 as an "input mechanism" composed of a keyboard, a mouse, a touch panel, etc., a display device 73 as a "display mechanism" having a display screen such as a CRT or a liquid crystal, an image data storage device 74 for storing various image data, etc., a calculation result storage device 75 for storing various calculation results, etc., a setting data storage device 76 for pre-storing various information, etc. In addition, each of these devices 72 to 76 is electrically connected to the CPU, etc. 71.

[0133] The CPU 71 is connected to the PTP packaging machine 10 in a manner capable of transmitting and receiving various signals. Thus, for example, a defective sheet discharge mechanism of the PTP packaging machine 10 can be controlled.

[0134] The image data storage device 74 is used to store the spectroscopic image data captured by the imaging device 53 , the spectral image data obtained based on the spectroscopic image data, the binarized image data after binarization processing, and the like.

[0135] The calculation result storage device 75 stores the inspection result data, statistical data obtained by probabilistically statistically processing the inspection result data, etc. These inspection result data and statistical data can be appropriately displayed on the display device 73.

[0136] The setting data storage device 76 stores, for example, the loading vector used in the principal component analysis, the determination range, the shapes and sizes of the PTP sheet 1 , the pocket 2 , and the tablet 5 , and the like.

[0137] Next, the flow of the different-type mixing inspection (inspection step) performed by the inspection device 22 will be described.

[0138] First refer to Figure 7 The process of obtaining spectral data by obtaining spectral data is described in the flowchart of FIG. 1. In addition, this process is a process that is repeatedly performed every time the container film 3 is transported according to a predetermined amount.

[0139] First, in step S01 , the control processing device 54 irradiates the container film 3 (tablets 5 ) being continuously transported with near-infrared light from the lighting device 52 (irradiation step), and simultaneously performs imaging processing (exposure processing) with the imaging device 53 .

[0140] Here, the control processing device 54 drives and controls the camera device 53 based on a signal from an encoder (not shown) provided in the PTP packaging machine 10 , and acquires the spectroscopic image data captured by the camera device 53 into the image data storage device 74 .

[0141] Thus, during the period (exposure period) of the imaging process in step S01, the near-infrared light irradiated from the lighting device 52 toward the container film 3 is emitted within the imaging range W in the conveying direction (see Fig.10 ) is incident on the imaging device 53. That is, the imaging range W in the conveying direction is imaged by one imaging process.

[0142] In addition, like Fig.10 As shown, in this embodiment, the imaging process is performed every time the container film 3 is transported by a predetermined amount, thereby imaging the spectral spectra of a plurality of locations in the transport direction for one tablet 5 .

[0143] The reflected light incident on the imaging device 53 is split by the two-dimensional spectroscope 62 (spectral splitting step), and is imaged as a spectroscopic image (spectral spectrum) by the imaging element 65 of the camera 63 (image capturing step).

[0144] Figure 8 Schematic diagram showing a state in which a spectral spectrum H of reflected light reflected at a predetermined position on the tablet 5 is projected onto the photosensitive surface 65a of the imaging element 65. Figure 8 In FIG. 1 , for convenience, only the spectral spectrum H of the tablet 5 is shown, and the spectral spectrum of other parts is omitted.

[0145] The spectroscopic image (spectral spectrum) data captured by the imaging device 53 is output to the control processing device 54 during the interval period and stored in the image data storage device 74. In addition, the interval period referred to here refers to the period during which the image data is read. That is, the imaging cycle of the imaging device 53 can be represented by the total time of the exposure period and the interval period as the execution period of the imaging process.

[0146] After obtaining the spectral image data, the control processing device 54 starts the data generation process of step S02 .

[0147] In the data generation process, spectrum data is generated based on the spectroscopic image data obtained in step S01. When the spectrum data is generated, it is stored in the image data storage device 74, and this flow is temporarily terminated.

[0148] Then, like Fig.10 As shown in FIG. 1 , each time the container film 3 (tablet 5) is transported by a predetermined amount, the transport direction imaging range W is intermittently moved relatively, and the above-mentioned spectral data acquisition process is repeated. Thus, in the image data storage device 74, the spectral data corresponding to each transport direction imaging range W and the position information in the film transport direction (X direction) and the film width direction (Y direction) are sequentially stored in a time series. Thus, a two-dimensional spectral image Q having spectral data for each pixel is generated (see FIG. 1 ). Fig.11).

[0149] Here, the spectral image Q in this embodiment is described. Fig.11 As shown, the spectral image Q is image data in which a plurality of pixels Qa are arranged two-dimensionally. Each pixel Qa includes spectral data (data indicating spectral intensities (brightness values) of a plurality of wavelength components (wavelength ranges)).

[0150] Next, if a predetermined inspection range (refer to Fig.11 If a spectral image Q is obtained by scanning a pixel of a semiconductor device 52 (shown as a double-dotted line), the control processing device 54 executes the inspection procedure.

[0151] Refer to the following Fig. 9 The inspection procedure is described with reference to the flowchart of . In addition, this process is repeated each time the spectrum image Q of the above-mentioned inspection range is obtained.

[0152] The control processing device 54 first executes tablet pixel extraction processing in step S11. In this processing, pixels Qb corresponding to the tablet 5 to be analyzed (hereinafter referred to as "tablet pixels") are extracted from each pixel Qa of the spectral image Q.

[0153] In this embodiment, for example, it is determined whether the spectral intensity of a predetermined wavelength in the spectral data of each pixel Qa is above a predetermined threshold value, and the spectral image Q is binarized. Then, tablet pixels Qb are extracted based on the obtained binarized image data (see Fig.10 and Fig.11 ).

[0154] picture Fig.10 As shown, in the present embodiment, the pixel Qa including the data of only the range of the tablet 5 is extracted as the tablet pixel Qb without being affected by the background. Fig.10 : is an explanatory diagram for explaining the relationship between the transmission direction imaging range W and the spectral image Q. Fig.10 , Fig.11 In FIG. 1 , pixels extracted as tablet pixels Qb are indicated by oblique lines.

[0155] In addition, the method of extracting tablet pixels Qb is not limited to this, and other methods may be used. For example, the following structure may be used: the cumulative value of spectral data (spectral intensity of each wavelength component) is calculated for each pixel Qa, and the tablet pixel Qb is extracted by determining whether the value is above a predetermined threshold.

[0156] Next, the control processing device 54 executes a tablet region specifying process in step S12. Through this process, the region of the ten tablets 5 received in each pocket 2 within the inspection range is specified.

[0157] In the present embodiment, for example, the tablet pixels Qb obtained in step S11 are subjected to labeling processing, and all adjacent tablet pixels Qb are considered to be connected components of tablet pixels Qb belonging to the same tablet 5 .

[0158] Thus, the range of one connecting component can be specified as the tablet region of one tablet 5 received in a predetermined pocket 2 (see Fig.10 , Fig.11 ).exist Fig.10 , Fig.11 In FIG. 1 , connected components (tablet regions) of a plurality of tablet pixels Qb belonging to each tablet 5 are surrounded by thick frames.

[0159] Furthermore, the spectrum data of a plurality of tablet pixels Qb included in one connected component (tablet region) can be treated as spectrum data of a plurality of points (a plurality of coordinate positions) on one tablet 5 .

[0160] That is, the spectral data acquisition step in this embodiment is composed of a series of processing steps, which include a data generation step in step S02, a tablet pixel extraction step in step S11, and a tablet area identification step in step S12, and the spectral data acquisition mechanism in this embodiment is composed of the functions of the control processing device 54 that executes the process.

[0161] The method of specifying the area of ​​tablet 5 is not limited to this, and other methods may be used. For example, pixels included in a predetermined range centered on a specific pixel may be determined as pixels belonging to the same tablet 5 as the specific pixel.

[0162] Next, the control processing device 54 performs a median spectrum acquisition process in step S13. In this process, for each tablet region designated in step S12, median spectrum data of each tablet 5 is acquired using spectrum data of a plurality of tablet pixels Qb contained therein.

[0163] More specifically, regarding the spectrum data of a plurality of tablet pixels Qb belonging to a tablet region of one tablet 5, the median value of the spectrum intensity (brightness value) is selected for each wavelength component. Then, the set of the median values ​​of the respective wavelength components is stored in the calculation result storage device 75 as the median spectrum data of the tablet 5.

[0164] That is, the processing step of selecting the intermediate value for each wavelength component constitutes the intermediate value selecting step in this embodiment, and the function of the control processing device 54 that executes this step constitutes the intermediate value selecting means in this embodiment.

[0165] Below, refer to Figure 12 to Figure 14The specific example shown explains a process of selecting the median value of the spectrum intensity for each wavelength component and obtaining the median spectrum data.

[0166] Fig.12 1 is a schematic diagram showing an example of a plurality of coordinate points A to E at which spectrum data is obtained on one tablet 5 . Fig.13 This is a table showing an example of spectrum data (spectral intensity of each wavelength component) obtained at coordinate points A to E. Fig.14 A graph plotted through spectral data.

[0167] picture Fig.12 As shown, the coordinate point A is located within the dividing line 5F, and includes a shadow portion where the brightness of the reflected light decreases. Fig.13 and Fig.14 As shown, the spectrum data of the coordinate point A is generally low in brightness.

[0168] Coordinate point B is located at the tapered portion 5D on the side away from the lighting device 52 (see Fig.12 ), and includes a shadow portion with low brightness of reflected light, similarly to coordinate point A. Therefore, the spectrum data associated with coordinate point B is also data with low brightness as a whole (see Fig.13 and Fig.14 ).

[0169] On the other hand, the coordinate point E is located at the boundary between the tapered portion 5D on the side closer to the lighting device 52 and the flat surface of the surface 5B (see Fig.12 ), including the mirror reflection part (reflection part) such as the corner part where the brightness of the reflected light becomes high. Therefore, the spectrum data related to the coordinate point E is generally high brightness data (see Fig.13 and Fig.14 ).

[0170] In contrast, coordinate points C and D are located on the flat surface of surface 5B (see Fig.12 ), which includes neither the shadow part nor the mirror reflection part. Therefore, the spectrum data of coordinate points C and D are data that more appropriately reflect the composition of tablet 5 (refer to Fig.13 , Fig.14 ).

[0171] exist Fig.13 and Fig.14 In the example shown, based on the spectrum data of the plurality of coordinate points A to E, the spectrum intensity "3" of the 900 nm wavelength band associated with the coordinate point D is selected as the middle value of the 900 nm wavelength band. Fig.13 In order to easily identify the intermediate value, a scatter pattern is added to the portion corresponding to the intermediate value.

[0172] Then, the spectrum intensity "4" of the wavelength 1000 nm band associated with the coordinate point C is selected as the middle value of the wavelength 1000 nm band.

[0173] Similarly, regarding the middle values ​​of each wavelength component in the wavelength band of 1100nm to 1700nm, the spectral intensities of each wavelength component in the wavelength band of 1100nm to 1700nm at coordinate point C are selected as "7", "4", "4", "4.5", "5", and "7".

[0174] Furthermore, the spectral intensities "7", "4", and "3" of the wavelength components of the wavelength band of 1800 nm to 2000 nm associated with the coordinate point D are selected from the intermediate values ​​of the wavelength components of the wavelength band of 1800 nm to 2000 nm.

[0175] Then, the set of intermediate values ​​of each wavelength component selected in this way (see Fig.13 The median spectral data for Tablet 5 were obtained by spectral analysis (right column of the table).

[0176] Here, as observed Fig.13 and Fig.14 As judged by the average value of the spectral intensity (brightness value) of the wavelength component of the spectral data of the multiple coordinate points A to E shown, the average value is affected by the spectral data related to the coordinate points A, B and E which basically constitute the noise component (the influence of the shadow portion generated at the dividing line 5F and the tapered portion 5D and the influence of the reflection caused by the mirror reflection), and is not approximate to the spectral data related to the relatively appropriate coordinate points C and D.

[0177] On the other hand, the intermediate value spectrum data is data that is close to the spectrum data related to relatively appropriate coordinate points C and D, as judged by comparison with the average value.

[0178] In this way, when the corresponding median spectrum data of 10 tablets 5 received in each bag portion 2 within the inspection range are obtained, the control processing device 54 collects them as a median spectrum data group of one inspection range and stores them in the calculation result storage device 75.

[0179] In the next step S14, the control processing device 54 sets the count value P of the bag number counter set in the calculation result storage device 75 to an initial value, that is, "1".

[0180] The so-called "bag number" is a continuous number set corresponding to each of the ten bags 2 within one inspection range, and the position of the bag 2 can be specified according to the count value P of the bag number counter (hereinafter simply referred to as the "bag number count value P"). Fig.11 ”.

[0181] exist Fig.11 In the example shown, for example, the top pocket 2 in the left column is set to pocket 2 corresponding to the pocket number count value [1], and the bottom pocket 2 in the right column is set to pocket 2 corresponding to the pocket number count value

[10] .

[0182] Next, the control processing device 54 performs analysis object data extraction processing in step S15. In this processing, based on the median spectrum data group of one inspection range (median spectrum data of 10 tablets 5) obtained in the above step S13, the median spectrum data of the tablets 5 stored in the bag portion 2 corresponding to the current bag number count value P (for example, P=1) is extracted.

[0183] Then, the control processing device 54 performs analysis processing on the median spectrum data of the tablet 5 extracted in step S15 (step S16). This processing corresponds to the analysis step in this embodiment, and the function of the control processing device 54 executing this processing constitutes the analysis means in this embodiment.

[0184] For example, in this embodiment, principal component analysis (PCA) is performed on the median spectrum data of tablet 5 obtained in step S13 using the previously obtained loading vectors. More specifically, the principal component score is calculated by calculating the loading vectors and the median spectrum data of tablet 5.

[0185] Next, the control processing device 54 performs a process of determining whether the tablet is good or not in step S17. In this process, based on the analysis result of the analysis process in step S16, it is determined whether the tablet 5 received in the bag portion 2 corresponding to the current bag number count value P (for example, P=1) is a good product (same variety) or a defective product (different variety).

[0186] More specifically, the principal component scores calculated in the above step S16 are plotted on the PCA graph. If the plotted data is within the pre-set good product range, it is judged as a good product (same variety). If it is outside the good product range, it is judged as a defective product (different variety).

[0187] Then, the control processing device 54 stores the judgment result of the tablet 5 , “good” or “bad”, in the calculation result storage device 75 .

[0188] Then, the control processing device 54 adds "1" to the current bag number count value P in step S18, and then moves to step S19 to determine whether the newly set bag number count value P exceeds the maximum value Pmax. The maximum value Pmax is the maximum value of the number of bag portions 2 within one inspection range ("10" in this embodiment).

[0189] If the determination is negative, the process returns to step S15 and the above series of processes are performed. On the other hand, if the determination is positive, the determination of whether the tablets 5 in all the pockets 2 are good or not is considered to be completed and the process moves to step S20.

[0190] In the next step S20, the control processing device 54 executes a good or bad tablet determination process. In this process, based on the determination result of the good or bad tablet determination process in step S17, it is determined whether the PTP tablet 1 corresponding to the inspection range is a good product or a defective product.

[0191] Specifically, if there is even one tablet 5 judged as "defective" within the inspection range, the PTP sheet 1 corresponding to the inspection range is judged as "defective" and the process proceeds to step S21.

[0192] On the other hand, when there is not even one tablet 5 judged as "defective" within the inspection range, the PTP sheet 1 corresponding to the inspection range is judged as "good", and the process proceeds to step S22.

[0193] Next, in the defective product processing of step S21, the control processing device 54 stores the "defective product" judgment result of the PTP sheet 1 in the calculation result storage device 75, and outputs the content to the defective sheet discharge mechanism of the PTP packaging machine 10, etc., to end the inspection program.

[0194] On the other hand, in the good product processing of step S22, the control processing device 54 stores the "good product" judgment result of the "inspection range" of the PTP sheet 1 in the calculation result storage device, and ends the inspection program.

[0195] As described above, according to the present embodiment, even when there are errors in the data of multiple coordinate points on a tablet 5, the singular point (e.g., Fig.12 By excluding the spectral data of the coordinate points A, B, E, etc. in the figure, spectral data (intermediate spectral data) suitable for spectroscopic analysis of the tablet 5 can be obtained.

[0196] Thus, even when the tablet 5 has the dividing line 5F, the conical portion 5D, etc., the influence of the shadow portion caused by the dividing line 5F, etc., the reflection caused by the corners, etc. can be avoided, and the tablet 5 can be properly inspected.

[0197] As a result, compared with a method of simply averaging the spectrum data at a plurality of points on the tablet 5, etc., it is possible to significantly improve the inspection accuracy of the different-brand contamination inspection.

[0198] In addition, the present invention is not limited to the contents described in the above-mentioned embodiments, and may be implemented as follows, for example. Of course, other application examples and modification examples not listed below are also possible.

[0199] (a) In the above embodiment, the object is embodied as a tablet 5, but the type of the object is not particularly limited, and may be, for example, a capsule, a supplement, a food, etc. Tablets include solid preparations such as bare tablets and sugar-coated tablets.

[0200] Furthermore, when inspecting capsules, the specularly reflected light reflected by the capsule portion becomes reflected light, which may affect the inspection of the tablets inside. However, according to the present invention, the occurrence of such a problem can be suppressed.

[0201] The shape of the object is not limited to the above embodiment. In the above embodiment, the tablet 5 is a bare tablet that is a circular disc-shaped tablet when viewed from a plane, and tapered portions 5D and 5E are formed on the outer edges of the inner and outer surfaces 5B and 5C, and a dividing line 5F is engraved on the surface 5B.

[0202] The present invention is not limited to this, and a tablet in which the tapered portions 5D and 5E and / or the dividing line 5F are omitted may be used as the object. In addition, a tablet having a mark as a concave portion may be used as the object.

[0203] In addition, for example, a lens agent that is circular in plan view and has different thicknesses in the middle and the periphery, or a tablet that is substantially elliptical, substantially oblong, or substantially polygonal in plan view may be used as the object.

[0204] (b) The materials of the container film 3 and the cover film 4 are not limited to those in the above embodiment, and other materials may be used. For example, the container film 3 may be a structure formed of a metal material mainly composed of aluminum, such as an aluminum laminate film.

[0205] (c) The arrangement and number of the pockets 2 of the PTP sheet 1 are not limited to the above-described embodiment, and a PTP sheet having various arrangements and numbers, for example, including a type having 12 pockets in three rows, may be used.

[0206] (d) In the above-mentioned embodiment, the following scheme is formed, wherein, in the subsequent step of filling the tablets 5 into the bag portion 2 and in the prior step of installing the cover film 4 relative to the container film 3, the tablets 5 are illuminated and photographed from the open side of the bag portion 2 by the inspection device 22 to perform an inspection for mixing of different varieties.

[0207] Without being limited to this, the following scheme may be formed, wherein, when the container film 3 is formed of a transparent material, in a step after the tablets 5 are filled in the bag portion 2, and in a prior step of installing the cover film 4 on the container film 3, the tablets 5 are illuminated and photographed by the inspection device 22 across the bag portion 2 (container film 3) to perform an inspection for mixing of different varieties.

[0208] Furthermore, when the tablet 5 is inspected by lighting and imaging through the bag 2, there is a risk that the specularly reflected light reflected by the bag 2 will become reflected light and affect the inspection. However, according to the present invention, such an inconvenience can be suppressed.

[0209] In addition, the following scheme can also be formed, wherein, in the subsequent step of installing the cover film 4 relative to the container film 3, and in the prior step of punching the PTP sheet 1 from the PTP film 6, the inspection device 22 is used to illuminate and photograph the tablet 5 from the container film 3 side of the PTP film 6 across the bag portion 2 to perform an inspection for mixing of different varieties.

[0210] In addition, the following scheme can also be formed, in which, in the subsequent step of punching the PTP sheet 1 from the PTP film 6, the inspection device 22 is used to illuminate and photograph the tablet 5 from the container film 3 side of the PTP sheet 1 transported by the conveyor 39, across the bag portion 2, to perform an inspection for mixing of different varieties.

[0211] In this case, instead of the configuration in which the inspection device 22 is provided in the PTP packaging machine 10 (online), a configuration may be formed in which the inspection device 22 is provided as a device for inspecting the PTP sheet 1 off-line, separate from the PTP packaging machine 10. In this case, a configuration may also be formed in which the inspection device 22 has a conveying mechanism that can convey the PTP sheet 1.

[0212] In addition, a scheme may be formed in which the inspection device 22 performs the inspection of different varieties of tablets 5 in a previous step of filling the bag portion 2. For example, a scheme may be formed in which the inspection is performed in a previous stage of feeding the tablets 5 into the tablet filling device 21. That is, a scheme may be formed in which the inspection device 22 is provided as a device for inspecting the tablets 5 off-line, separately from the PTP packaging machine 10.

[0213] In addition, when the inspection is performed offline, the PTP sheet 1 and the tablet 5 may be transported discontinuously and the inspection may be performed in a stopped state. However, in order to improve productivity, it is preferred to continuously transport the PTP sheet 1, the PTP film 6 or the container film 3 while performing the inspection online.

[0214] In recent years, in the field of manufacturing PTP sheets 1, with the increase in production speed, various inspections such as inspection of mixed products have been required to be performed at a higher speed. For example, when performing inspections on a PTP packaging machine 10, it is required to inspect more than 100 tablets 5 per second.

[0215] (e) The configurations of the illumination device 52 and the imaging device 53 are not limited to those of the above-described embodiment. For example, a reflective diffraction grating or a prism may be used as a spectroscopic mechanism instead of the two-dimensional spectroscope 62 .

[0216] (f) In the above embodiment, the spectral data is analyzed by principal component analysis (PCA), but the present invention is not limited thereto and other known methods such as PLS regression analysis may be used for analysis.

[0217] (g) In the above-mentioned embodiment, the following scheme is formed, wherein, in the intermediate value spectrum acquisition process of step S13, for the spectrum data of multiple coordinate points on a tablet 5, the intermediate value of the spectrum intensity is selected for each wavelength component, and a set of the intermediate values ​​selected for each of these wavelength components is obtained as the intermediate value spectrum data of the tablet 5, and in the analysis process of step S16, the intermediate value spectrum data is analyzed and processed, thereby performing a mixed inspection of different varieties of the tablet 5.

[0218] The present invention is not limited to this, and the following structure can be adopted, wherein, instead of the intermediate value spectrum acquisition processing in step S13, a representative spectrum acquisition processing is performed, in which representative spectrum data representing tablet 5 is selected from the spectrum data of multiple coordinate points on a tablet 5, and in the analysis processing in step S16, the representative spectrum data is analyzed and processed, thereby performing a mixed inspection of different varieties related to tablet 5.

[0219] Here, the representative spectrum selecting step of the present embodiment is constituted by the step of executing the representative spectrum obtaining process, and the representative spectrum selecting means of the present embodiment is constituted by the function of the control processing unit 54 that executes the representative spectrum selecting process.

[0220] For the representative spectrum acquisition process, the following scheme is listed, in which the following spectral data is selected from the spectral data of multiple coordinate points on a tablet 5 as representative spectral data representing the tablet 5, and the spectral data is that the addition value of the spectral intensity (brightness value) in a predetermined wavelength range (multiple wavelength range groups) is at an intermediate value.

[0221] exist Fig.13In the specific example shown, when the representative spectrum acquisition process is performed, for example, the sum of the spectrum intensities of the wavelength components (wavelength ranges) in the full wavelength range (range of wavelength 900nm to wavelength 2000nm) of the spectrum data obtained at the plurality of coordinate points A to E on one tablet 5 is calculated. Here, the sum of the spectrum intensities associated with the plurality of coordinate points A to E is "6", "11", "59", "62.5", and "114", respectively. In addition, since the sum "59" is the middle value of these values, the spectrum data associated with the corresponding coordinate point C is selected as the representative spectrum data of the representative tablet 5.

[0222] Instead of this method, the following scheme can be formed, in which the following spectral data can be selected from the spectral data of multiple coordinate points A to E as representative spectral data representing tablet 5, in which spectral data, the sum of the spectral intensities of each wavelength component within a partial wavelength range (for example, a wavelength range of 1800nm ​​to 2000nm) is an intermediate value.

[0223] exist Fig.13 In the example shown, the spectral data in which the sum of the spectral intensities of the wavelength components within the wavelength range of 1800 nm to 2000 nm becomes an intermediate value is the spectral data regarding the coordinate point D. In this case, the spectral data regarding the coordinate point D is selected as the representative spectral data representing the tablet 5.

[0224] In addition, as a representative spectrum acquisition process, for example, the following spectral data can be selected from the spectral data of multiple coordinate points on a tablet 5 as representative spectral data representing tablet 5, which is spectral data whose spectral intensity (brightness value) within a predetermined wavelength (a wavelength range) is at an intermediate value.

[0225] For example, in Fig.13 In the example shown, the following spectrum data is selected as the representative spectrum data representing the tablet 5, wherein the spectrum data obtained at the plurality of coordinate points A to E on the tablet 5 have a spectrum intensity at an intermediate value within a wavelength range of 1500 nm. In this case, the spectrum data associated with the coordinate point C is selected as the representative spectrum data representing the tablet 5.

[0226] On the other hand, when the spectrum data is selected as the representative spectrum data representing tablet 5, the spectrum intensity in the wavelength range of 900 nm is at the center value. In this case, the spectrum data associated with coordinate point D is selected as the representative spectrum data representing tablet 5.

[0227] However, since the spectral intensity of each wavelength band included in the near-infrared light emitted from the light source is not uniform, it is preferable to select the following spectral data as representative spectral data representing tablet 5, which is spectral data in which the sum of spectral intensities of multiple wavelength band groups is an intermediate value.

[0228] In this regard, the above embodiment of performing the inspection for different kinds of mixture of tablets 5 based on the intermediate value spectrum data composed of the intermediate values ​​selected for each wavelength component is more preferable than the scheme of performing the inspection for different kinds of mixture of tablets 5 based on the representative spectrum data.

[0229] (h) In the above embodiment, a scheme is formed in which the image pickup process is performed every time the container film 3 is transported by a predetermined amount, thereby obtaining spectral data of a plurality of locations in the film transport direction (X direction) for one tablet 5. Without being limited to this, a scheme may be formed in which spectral data of only one location in the film transport direction (X direction) is obtained for one tablet 5. Also in this case, spectral data of a plurality of locations in the film width direction (Y direction) of the container film 3 is obtained for one tablet 5.

[0230] Description of the label:

[0231] Reference numeral 1 indicates a PTP sheet;

[0232] Reference numeral 2 indicates a bag portion

[0233] Reference numeral 3 denotes a container film;

[0234] Reference numeral 4 represents a mask;

[0235] Reference numeral 5 indicates a tablet;

[0236] Reference numerals 5D and 5E denote tapered portions;

[0237] Reference numeral 5F indicates a dividing line;

[0238] Reference numeral 10 denotes a PTP packaging machine;

[0239] Reference numeral 22 denotes an inspection device;

[0240] Reference numeral 52 denotes a lighting device;

[0241] Reference numeral 53 denotes a camera device;

[0242] Reference numeral 54 denotes a control processing device;

[0243] Reference numeral 62 denotes a two-dimensional spectrometer;

[0244] Reference numeral 63 denotes a camera;

[0245] The symbol Q represents a spectral image;

[0246] The symbol Qa represents a pixel;

[0247] Symbol Qb represents a tablet pixel.

Claims

1. An inspection device, comprising: an irradiation mechanism capable of irradiating a target object with near-infrared light; a spectroscopic mechanism capable of spectroscopically splitting reflected light reflected from the object irradiated with the near-infrared light; A camera mechanism capable of photographing a spectroscopic image of the reflected light split by the spectroscopic mechanism; a spectral data acquisition mechanism capable of acquiring spectral data of a plurality of points on the object based on the spectral image acquired by the imaging mechanism; a representative spectrum selecting means for selecting, from the spectrum data of the plurality of points, spectrum data in which an added value of brightness values ​​in a predetermined wavelength range constitutes an intermediate value as representative spectrum data representing the object; The analyzing means can detect different varieties by performing a predetermined analysis process on the object based on the representative spectrum data.

2. A PTP packaging machine for manufacturing a PTP sheet in which an object is received in a bag formed on a container film and a cover film is installed in a manner to close the bag, characterized in that: The PTP packaging machine includes: a pocket forming mechanism for forming the pocket on the strip-shaped container film; a filling mechanism for filling the object into the bag portion; An installation mechanism, the installation mechanism installs the strip-shaped cover film on: the container film filled with the object in the bag portion in a manner that the bag portion is closed; a cutting mechanism for cutting the PTP sheet from a strip-shaped body on which the cover film is mounted on the container film; and The inspection device according to claim 1.

3. A method for manufacturing a PTP sheet, wherein an object is received in a bag portion formed on a container film, and a cover film is installed in a manner to close the bag portion, characterized in that: The manufacturing method of the PTP sheet comprises: a bag portion forming step, in which the bag portion is formed on the strip-shaped container film; a filling step in which the object is filled into the bag portion; An installation step, in which the strip-shaped cover film is installed on the container film filled with the object in the bag portion in a manner to close the bag portion; a cutting step, in which the PTP sheet is cut from a strip body on which the cover film is mounted on the container film; an inspection step, in which the mixing of different varieties is checked; The above inspection steps include: an irradiation step of irradiating the object with near-infrared light; a spectroscopic step of spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically spectroscopically on reflected light reflected from the object irradiated with the near-infrared light; an imaging step, in which a spectroscopic image of the spectroscopic reflected light is photographed; a spectral data obtaining step, in which spectral data of a plurality of points on the object are obtained based on the spectral image; a representative spectrum selecting step, in which spectrum data of which the sum of the brightness values ​​in a predetermined wavelength range becomes an intermediate value is selected from the spectrum data of the plurality of points as representative spectrum data representing the object; An analysis step in which a different variety is detected by performing a predetermined analysis process on the object based on the spectral data.

Images