A blood clot-clearing nanorobot

By designing a thrombus cleaning nanorobot including a spindle-shaped robot body, a spiral coil, a connecting rod and a magnetic ball, it uses magnetic driving to rotate and advance in the blood vessels, and solves the problem of difficulty in effectively cleaning the thrombus in the prior art, achieving an efficient and convenient thrombus cleaning effect.

CN112807057BActive Publication Date: 2025-05-23JILIN YIFANG TECH CO LTD
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Patent Information

Application Number
CN202110141188.1
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2021-02-01
Publication Date
2025-05-23
Estimated Expiration
2041-02-01

AI Technical Summary

Technical Problem

The prior art is difficult to effectively clean thrombus, especially in tiny blood vessels, and traditional thrombus treatment methods have certain risks and inconveniences.

Method used

A thrombolysis nanorobot was designed, including a spindle-shaped robot body, a spiral coil, an elastic connecting rod and a magnetic ball. Through the control of magnetic patches and control chips, the nanorobot is driven to rotate and advance in the blood vessels by magnetic force, and the thrombus is crushed by the swing of the magnetic ball.

Benefits of technology

It realizes the function of efficiently cleaning thrombus in the blood vessels, which is easy to use and easy to recover, reducing the risks and inconvenience of traditional treatment methods.

✦ Generated by Eureka AI based on patent content.

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    Figure CN112807057B_ABST
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Abstract

The present invention discloses a thrombus-clearing nanorobot, and the technical scheme thereof mainly includes a spindle-shaped robot body; a threaded spiral coil is arranged at the end of the robot body; an elastic connecting rod is arranged in the spiral coil; the two ends of the connecting rod are respectively connected to the robot body and a magnetic ball; the robot body is made of magnetic material; the line between the robot body and the magnetic ball is the central axis, the robot body above the central axis is the N pole and the magnetic ball is the S pole, the robot body below the central axis is the S pole and the magnetic ball is the N pole, and the spiral coil is a double spiral coil; a connecting ring is arranged at the end of the robot body; the end face of the connecting ring is fixedly connected to the spiral coil; the connecting rod is made of metal tantalum; the cross section of the spiral coil is flat; the present invention has the beneficial effects of clearing thrombus, being convenient to use and easy to recover.
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Description

Technical Field

[0001] The present invention relates to the field of thrombus dredging, and more specifically to a thrombus clearing nanorobot. Background Art

[0002] With the continuous improvement of people's living standards and the increase of social pressure, more and more people are suffering from thrombosis. Thrombosis is a substance that is very harmful to the human body. It will affect the blood circulation of the human body and cause cardiovascular diseases. If symptoms of thrombosis appear in the heart, it may cause adhesion of the valve, which may cause valvular insufficiency and bacterial endocarditis. When the thrombus does not completely block the blood vessel, it is easy to cause ischemia of the organ, and it may also form emboli, which will separate from the blood vessel wall and flow to various parts of the body with the blood, causing embolism. If the thrombosis is more serious, the blood vessels are completely blocked, and the blood cannot flow to the local organs, ischemic necrosis occurs, and it is more likely to cause bleeding or shock symptoms. Thrombosis is threatening people's health step by step. With the continuous improvement of medical level, more and more people want to get rid of the trouble of thrombosis, and the treatment of thrombosis is urgent.

[0003] The working environment of nanorobots is in an environment with a very low Reynolds coefficient. Objects can be regarded as moving in a very viscous, tiny and slow environment. Viscous force plays a dominant role and inertial force can be ignored. Under such conditions, if you want to drive the micro-nano robot, you must provide it with power continuously. However, due to its tiny size, power sources such as batteries and engines are difficult to load into micro-nano robots. Therefore, various micro-nano robot driving methods have been proposed, including self-driving (self-electrophoresis driving, self-diffusion phoresis driving, self-thermophoresis driving, bubble driving, etc.) and external field driving (magnetic field, sound field and light driving). Since the magnetic field driving method has a low magnetic field intensity and the low-frequency magnetic field can penetrate biological tissues and is harmless to organisms, it has become one of the most promising driving methods in the field of nanorobots. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a thrombus-clearing nanorobot, which has the beneficial effects of clearing thrombus and being easy to use and recover.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a thrombus clearing nanorobot, characterized in that: it includes a spindle-shaped robot body; a threaded spiral coil is arranged at the end of the robot body; an elastic connecting rod is arranged inside the spiral coil; the two ends of the connecting rod are respectively connected to the robot body and a magnetic ball; the robot body is made of magnetic material; the connecting line between the robot body and the magnetic ball is the central axis, the robot body above the central axis is the N pole and the magnetic ball is the S pole, and the robot body below the central axis is the S pole and the magnetic ball is the N pole.

[0006] By adopting the above technical solution: the nanorobot is injected into the vein or artery of the human body with thrombosis through a syringe, and is developed under the irradiation of X-rays. Then the magnetic patch performs magnetic force conversion under the control of the control chip, and applies magnetic forces in different directions to the nanorobot. Because of the different magnetic pole settings of the robot body, it can rotate during the magnetic force conversion, and because of the setting of the spiral coil on the back side of the robot body, the robot body can be pushed forward during rotation to achieve movement. The magnetic pole setting of the magnetic ball connected to the robot body through the connecting rod is opposite to that of the robot body, and the volume is smaller than the robot body, and the blood obstruction it encounters is also smaller than the robot body. When the magnetism on the magnetic patch changes, the magnetic ball can swing relative to the robot body, which can break up the thrombus in the blood vessel and facilitate the removal of the thrombus.

[0007] The present invention is further configured as follows: the spiral coil is a double spiral coil; a connecting ring is provided at the end of the robot body; the end face of the connecting ring is fixedly connected to the spiral coil; the connecting rod is made of metal tantalum; and the cross section of the spiral coil is flat.

[0008] By adopting the above technical solution: the structure of the spiral coil is flat. When the magnetic field of the magnetic patch changes and drives the robot body to rotate, the spiral coil will also rotate. During the rotation, the flat structure forms an inclined plane. During the rotation, the robot body is pushed forward or backward to achieve movement. At the same time, the material structure of the connecting rod has a certain elasticity, which can provide elastic restoring force when the magnetic ball swings.

[0009] The present invention is further configured as follows: the robot body is coated with a molecular motor for driving the robot body to move; and the molecular motor is configured as ATP synthase.

[0010] By adopting the above technical solution: molecular motors such as ATP synthase can provide power after entering the blood, facilitate the movement of the robot body, and facilitate the diffusion of nanorobots in blood vessels after injection.

[0011] The present invention is further configured as follows: the diameter of the robot body is 10nm to 20nm; the diameter of the magnetic ball is 8nm to 12nm; the length of the connecting rod is 15nm to 25nm, and the diameter is 2nm to 3.5nm.

[0012] The present invention is further configured to include: a syringe for injecting nanorobots; a magnetic patch and a control chip; the control chip controls the current to flow through the coupling coil arranged in the magnetic patch, thereby generating a magnetic field for driving the robot body and the magnetic ball to move.

[0013] By adopting the above technical solution: the syringe is an existing syringe, which is used to inject the nanorobot into the blood vessel, and the role of the magnetic patch is that when the nanorobot diffuses, the control chip controls the magnetic patch to generate a magnetic field, thereby controlling the nanorobot and treating the blood clot.

[0014] The present invention is further configured as follows: two magnetic patches are provided and adhered to the front and back sides of the affected part of the human body.

[0015] By adopting the above technical solution: if there is a thrombosis in the arm vein, two magnetic patches can be glued to both sides of the arm, and the current flow can be controlled by an external control chip to change the direction and size of the magnetic field, and the magnetic field can be used to control the nanorobots that have been injected into the affected blood vessels in advance. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is a schematic diagram of the structure of the nanorobot in this embodiment;

[0017] Figure 2 is a schematic diagram of the structure of the nanorobot in this embodiment;

[0018] Figure 3 Schematic diagram of the magnetic patch structure of this embodiment.

[0019] Figure numerals: 1. robot body; 2. spiral coil; 3. connecting rod; 4. magnetic ball; 5. connecting ring; 6. molecular motor; 7. adhesive layer; 8. coupling coil; 9. protective layer. DETAILED DESCRIPTION

[0020] The present invention is further described in detail below in conjunction with the accompanying drawings.

[0021] This embodiment discloses a thrombus-clearing nanorobot, such as Figures 1 to 3As shown, it has the beneficial effects of clearing blood clots, being easy to use and recovering: it comprises a spindle-shaped robot body 1; a threaded spiral coil 2 is arranged at the end of the robot body 1; an elastic connecting rod 3 is arranged inside the spiral coil 2; the two ends of the connecting rod 3 are respectively connected to the robot body 1 and the magnetic ball 4; the robot body 1 and the magnetic ball 4 are both made of magnetic materials; the line between the robot body 1 and the magnetic ball 4 is the central axis, the robot body 1 above the central axis is the N pole, the magnetic ball 4 is the S pole, and the robot body 1 below the central axis is the S pole, and the magnetic ball 4 is the N pole.

[0022] By adopting the above technical solution: the nanorobot is injected into the vein or artery of the human body with thrombosis through a syringe, and developed under the irradiation of X-rays, and then the magnetic patch performs magnetic force conversion under the control of the control chip to apply magnetic forces in different directions to the nanorobot. Because of the different magnetic pole settings of the robot body 1, it can be rotated during the magnetic force conversion, and because of the setting of the spiral coil 2 on the rear side of the robot body 1, the robot body 1 can be pushed forward during rotation to achieve movement. The magnetic pole setting of the magnetic ball 4 connected to the robot body 1 through the connecting rod 3 is opposite to that of the robot body 1, and the volume is smaller than the robot body 1, and the blood obstruction it encounters is also smaller than the robot body 1. When the magnetism on the magnetic patch changes, the magnetic ball 4 can swing relative to the robot body 1, which can break up the thrombus in the blood vessel and facilitate the removal of the thrombus.

[0023] The spiral coil 2 is a double spiral coil 2; a connecting ring 5 is provided at the end of the robot body 1; the end surface of the connecting ring 5 is integrally fixedly connected with the spiral coil 2; the connecting rod 3 is made of metal tantalum; the cross section of the spiral coil 2 is flat.

[0024] By adopting the above technical solution: the structure of the spiral coil 2 is flat. When the magnetic field of the magnetic patch changes and drives the robot body 1 to rotate, the spiral coil 2 will also rotate. During the rotation, the flat structure forms an inclined plane. During the rotation, the robot body 1 is pushed forward or backward to achieve movement. At the same time, the material structure of the connecting rod 3 has a certain elasticity, which can provide elastic restoring force when the magnetic ball 4 swings.

[0025] The robot body 1 is coated with a molecular motor 6 for driving the robot body 1 to move; the molecular motor 6 is configured as an ATP synthase.

[0026] By adopting the above technical solution: a molecular motor 6 such as ATP synthase can provide power after entering the blood, facilitating the movement of the robot body 1 and facilitating the diffusion of the nanorobot in the blood vessels after injection.

[0027] The diameter of the robot body 1 is 10nm-20nm; the diameter of the magnetic ball 4 is 8nm-12nm; the length of the connecting rod 3 is 15nm-25nm, and the diameter is 2nm-3.5nm.

[0028] It includes a syringe for injecting nanorobots; it also includes a magnetic patch and a control chip; the control chip controls the current to flow through the coupling coil 8 arranged in the magnetic patch, so as to generate a magnetic field for driving the robot body 1 and the magnetic ball 4 to move.

[0029] By adopting the above technical solution: the syringe is an existing syringe, which is used to inject the nanorobot into the blood vessel, and the role of the magnetic patch is that when the nanorobot diffuses, the control chip controls the magnetic patch to generate a magnetic field, thereby controlling the nanorobot and treating the blood clot.

[0030] Two magnetic patches are provided, which are attached to the front and back sides of the affected part of the human body. The structure of the magnetic patch includes an adhesive layer 7, the lower surface of the adhesive layer 7 is attached to the human skin, above the adhesive layer 7 is a coupling coil 8, and above the coupling coil 8 is a protective layer 9 bonded to the coupling coil 8. The coupling coil 8 is connected to an external control chip through a wire, and can also be connected to a computer. The current is controlled by a computer program, and the position of the affected part and the nanorobot is developed by X-ray and presented on a computer screen. After calculation, the position movement of the nanorobot is determined to achieve the effect of clearing blood clots.

[0031] By adopting the above technical solution: if there is a thrombosis in the arm vein, two magnetic patches can be glued to both sides of the arm, and the current flow can be controlled by an external control chip to change the direction and size of the magnetic field, and the magnetic field can be used to control the nanorobots that have been injected into the affected blood vessels in advance.

[0032] In the specific implementation process, the patient first undergoes an X-ray examination to preliminarily determine the location of the thrombus, and then the nanorobot is sucked into the syringe and injected into the thrombus through the vein or artery. The control chip controls the current to pass through the coupling coil 8 inside the magnetic patch, and at the same time generates a magnetic field. The nanorobot rotates and displaces under the action of the magnetic force. The control chip controls the movement of the nanorobot by controlling the size and direction of the current flowing in the coupling coil 8, thereby realizing the forward and backward movement of the nanorobot. After the dredging work is completed, the nanorobot is attracted to the appropriate position according to the X-ray display position with an electromagnet, and the nanorobot is extracted from the body with an injection, and the treatment is completed.

[0033] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the design concept of the present invention should be included in the protection scope of the present invention.

Claims

1. A thrombus-clearing nanorobot, Features: The invention comprises a spindle-shaped robot body (1); a threaded spiral coil (2) is arranged at the end of the robot body (1); an elastic connecting rod (3) is arranged inside the spiral coil (2); the two ends of the connecting rod (3) are respectively connected to the robot body (1) and a magnetic ball (4), and the volume of the magnetic ball (4) is smaller than that of the robot body (1); the robot body (1) is made of magnetic material; the line between the robot body (1) and the magnetic ball (4) is the central axis, the robot body (1) above the central axis is the N pole and the magnetic ball (4) is the S pole, and the robot body (1) below the central axis is the S pole and the magnetic ball (4) is the N pole; The spiral coil (2) is a double spiral coil (2); a connecting ring (5) is provided at the end of the robot body (1); the end surface of the connecting ring (5) is fixedly connected to the spiral coil (2); the connecting rod (3) is made of metal tantalum; and the cross section of the spiral coil (2) is flat.

2. The thrombus-clearing nanorobot according to claim 1, Features: The robot body (1) is coated with a molecular motor (6) for driving the robot body (1) to move; the molecular motor (6) is configured as an ATP synthase.

3. The thrombus-clearing nanorobot according to claim 2, Features: The diameter of the robot body (1) is 10nm to 20nm; the diameter of the magnetic ball (4) is 8nm to 12nm; the length of the connecting rod (3) is 15nm to 25nm, and the diameter is 2nm to 3.5nm.

4. A driving device for driving the thrombus-clearing nanorobot according to claim 3, Features: The invention comprises a syringe for injecting a nanorobot; a magnetic patch and a control chip; the control chip controls the current to flow through a coupling coil (8) arranged in the magnetic patch, thereby generating a magnetic field for driving the robot body (1) and a magnetic ball (4) to move; the magnetic ball (4) is smaller in volume than the robot body (1).

5. The driving device of the thrombus-clearing nanorobot according to claim 4, Features: The magnetic patches are provided with two pieces and are attached to the front and back sides of the affected part of the human body.

Citation Information

Patent Citations

  • Thrombus cleaning nano-robot

    CN215534798U