A quick box loading device for pipette tips

Abstract

The invention discloses a device for quickly loading pipette tips into boxes, comprising a porous screen plate and a tip transfer and loading mechanism. Bulk tips are poured onto the porous screen plate of the invention, so that the bulk tips can be arranged in order by gravity; the multiple tip pushers and tip inserts of the invention cooperate with each other, and only a few actions are required to complete the one-time transfer and positioning of a whole box of tips, thereby improving work efficiency and avoiding contact contamination of the tips.

Description

Technical Field

[0001] The invention belongs to the technical field of basic scientific research equipment, and in particular relates to a quick box-packing device for pipette tips. Background Art

[0002] The pipette, also known as a pipette gun, is an essential device in the basic scientific research of medicine, chemistry and biology. During operation, the elastic nozzle of the pipette is used in conjunction with the pipette tip. Usually these tips need to be placed in a tip box for easy access by the experimenter.

[0003] Due to the needs of precision experiments, a pipette tip cannot usually be reused continuously. It must be replaced after absorbing a liquid to prevent unnecessary cross contamination when absorbing other liquids. Therefore, as a common consumable in the laboratory, the consumption of pipette tips is very huge. After the daily work is completed, in order to ensure the orderly progress of subsequent experiments, a special person will be organized to manually load new pipette tips into the pipette tip box one by one. Due to the small size of the pipette tip, it is very inconvenient to take and put in the process of loading such pipette tips into the pipette tip box one by one, and it takes a lot of time, and even causes the hands of personnel to be stabbed by the pipette tip. The most important thing is that the manual filling of the pipette tip box is easy to cause the contamination of the pipette tip due to the operator's body accidentally touching the pipette tip, thereby causing the failure of subsequent sensitive experiments. There is no simple, portable and practical pipette tip filling device in the prior art to solve the above problems. Summary of the invention

[0004] The purpose of the present invention is to overcome the defects of the prior art and provide a device for quickly packing pipette tips.

[0005] The technical solution of the present invention is as follows:

[0006] A quick box loading device for pipette tips, comprising:

[0007] A porous sieve plate having a plurality of strip-shaped through grooves of the same size and arranged in parallel, so that the bulk pipette tips are regularly arranged vertically along the length direction of the plurality of strip-shaped through grooves, and the pipette connecting ends of the pipette tips face upward, the liquid aspirating ends of the pipette tips face downward, and the edges of the pipette connecting ends of adjacent pipette tips contact each other;

[0008] A tip transfer and loading mechanism, used for transferring the tips on the porous screen plate to the tip box, comprising at least one tip insert and at least one tip pusher adapted to the tip insert;

[0009] The tip insert comprises a first base; the first base has a plurality of hollow elastic nozzles arranged in sequence, the plurality of elastic nozzles can be interference fit with the pipette connecting ends of the tips arranged in the strip-shaped through grooves, and the center distance between adjacent elastic nozzles is the same as the center distance between adjacent strip-shaped through grooves; the first base also has at least one through groove communicating with the inner cavity of the elastic nozzles;

[0010] The suction head pusher comprises a second base; the second base has at least one push plate which can extend into at least one through slot of the first base;

[0011] The tip insert and the tip pusher are connected by at least one first elastic member, and the first elastic member has an extended state and a compressed state. When in the extended state, the push plate extends into the through slot but does not extend into the inner cavity of the elastic nozzle. When in the compressed state, the push plate extends into the inner cavity of the elastic nozzle through the through slot and penetrates the side wall of the elastic nozzle to push out the tip that is interference fit in the elastic nozzle and place the tip in the tip box.

[0012] In a preferred embodiment of the present invention, the center distance between adjacent strip-shaped through grooves in the length direction is equal to the center distance between the suction head holes in the length direction of the suction head box.

[0013] In a preferred embodiment of the present invention, the number of the strip-shaped through grooves is 5-50, the length is 5-100 cm, and the width is 3-20 mm.

[0014] In a preferred embodiment of the present invention, the first elastic member is a first spring.

[0015] In a preferred embodiment of the present invention, it further comprises a plurality of first guide rods and at least one limiting member, the first base of the suction head insert has a plurality of first through holes penetrating along the width direction thereof, the first guide rods extend into the first through holes to connect at least two suction head inserts, and a second elastic member is provided between adjacent suction head inserts; the second elastic member has an extended state and a compressed state, when in the extended state, two adjacent suction head inserts maintain a set spacing by at least one limiting member, and when in the compressed state, the center distance between two adjacent aligned elastic suction nozzles of two adjacent suction head inserts is equal to the center distance between adjacent suction heads arranged in the same strip-shaped through groove.

[0016] Further preferably, both ends of the pipette tip insert in the length direction have a limit piece adapter structure, and both ends of the first base of two adjacent pipette tip inserts in the length direction are respectively adapted with a limit piece through the limit piece adapter structure.

[0017] More preferably, the limiting member adaptation structure is a groove, and the limiting member includes two parallel limiting walls and a connecting wall connecting the two limiting walls, and the two limiting walls are respectively adapted to overlap with one side wall of the groove of the first base of two adjacent suction head inserts.

[0018] Further preferably, the second elastic member is a second spring.

[0019] Further preferably, it includes a plurality of second guide rods, the second base of the tip pusher has a plurality of second through holes extending therethrough along its width direction, the second guide rods extend into the second through holes to connect at least two tip pushers, and a third elastic member is provided between adjacent tip pushers; the third elastic member enables a change in the spacing between two adjacent tip pushers to adapt to a change in the spacing between two adjacent tip inserts.

[0020] More preferably, the third elastic member is a third spring.

[0021] In a preferred embodiment of the present invention, the number of the pipette tip inserts is 1-20.

[0022] In a preferred embodiment of the present invention, the porous sieve plate is made of metal, plastic or glass.

[0023] In a preferred embodiment of the present invention, the number of the elastic nozzles of the suction head insert is 1-20.

[0024] The beneficial effects of the present invention are:

[0025] 1. Pour the bulk pipette tips onto the porous sieve plate of the present invention, so that the bulk pipette tips can be arranged in order by gravity;

[0026] 2. The pipette tip inserting member and the pipette tip pushing member of the present invention cooperate with each other, and can simultaneously insert and transfer a plurality of pipette tips orderly arranged on the porous sieve plate to the pipette tip box.

[0027] 3. The multiple pipette tip inserts of the present invention are connected by the first guide rod, and the multiple pipette tip inserts can be combined according to specific needs to achieve simultaneous transfer and boxing of a large number of pipette tips, which greatly reduces the workload of the staff who box the pipette tips.

[0028] 4. The multiple tip pushers and tip inserts of the present invention cooperate with each other, and only a few actions are required to complete the one-time transfer and positioning of a whole box of tips, thereby improving work efficiency and avoiding contact contamination of the tips.

[0029] 5. The multiple tip pushers and tip inserts of the present invention can quickly adapt to the tip spacing of the porous sieve plate and the tip spacing of the tip box by adjusting the extension and compression states of the elastic member. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is a schematic diagram of the three-dimensional structure of the porous sieve plate of Example 1 of the present invention.

[0031] Figure 2 This is a schematic diagram of the three-dimensional structure of the arrangement of suction heads on the porous sieve plate of Example 1 of the present invention.

[0032] Figure 3 Schematic diagram of the three-dimensional structure of the tip transfer and loading mechanism of Example 1 of the present invention.

[0033] Figure 4 It is a three-dimensional exploded schematic diagram of the tip transfer and loading mechanism of Example 1 of the present invention.

[0034] Figure 5 It is a schematic diagram of the three-dimensional structure of the suction tip embedding component and the suction tip pushing component in the adapted and extended state according to Embodiment 1 of the present invention.

[0035] Figure 6 It is a schematic diagram of the three-dimensional structure of the suction tip embedding component and the suction tip pushing component in the adapted compressed state according to Example 1 of the present invention. DETAILED DESCRIPTION

[0036] The technical solution of the present invention is further illustrated and described below through specific implementation methods.

[0037] Example 1

[0038] A quick box loading device for pipette tips comprises a porous sieve plate 1 and a tip transfer loading mechanism 2. This embodiment takes a 96-hole tip box as an example.

[0039] like Figure 1 As shown, the porous sieve plate 1 (preferably made of metal, plastic or glass) has twelve strip-shaped through grooves 10 (oblong holes, rectangular holes or elliptical holes, preferably in the range of 5-50, with a length of 5-100 cm and a width of 3-20 mm) of the same size and arranged in parallel, so that the bulk pipette tips 3 are regularly arranged vertically along the length direction of the twelve strip-shaped through grooves 10, and the pipette connection end of the pipette tip 3 faces upward, the liquid absorption end of the pipette tip 3 faces downward, and the edges of the pipette connection ends of adjacent pipette tips 3 contact each other; the center distance of adjacent strip-shaped through grooves 10 in the length direction is equal to the center distance between the pipette holes in the length direction of the pipette tip box.

[0040] The specific arrangement process of the suction tips 3 on the porous sieve plate 1 is as follows: the porous sieve plate 1 is at a certain angle to the desktop, and then the bulk suction tips 3 are placed on the porous sieve plate 1 one after another while gently shaking or vibrating the porous sieve plate 1. The suction tips 3 perpendicular to the porous sieve plate 1 will fall into the strip-shaped through holes of the porous sieve plate 1, and the suction tips 3 that have not fallen into the strip-shaped through grooves 10 will fall into the suction tip recovery box. When there are a certain number of suction tips 3 on the porous sieve plate 1, the angle between the porous sieve plate 1 and the desktop is increased, and the suction tips 3 will slide to one end of the porous sieve plate 1 under the action of gravity, thereby achieving the suction tips 3 on the porous sieve plate 1. Figure 2 The close vertical arrangement shown.

[0041] like Figure 3 and 4 As shown, the tip transfer and loading mechanism 2 is used to transfer the tips 3 on the porous screen plate 1 to the tip box, and includes two clamping plates 21, four first guide rods 22, four second guide rods 23, two third guide rods 24, two groups of limiters 25 (eleven in each group), twelve tip inserts 26 (preferably in the range of 1-20) and twelve tip pushers 27 adapted to the tip inserts 26;

[0042] Each suction tip insert 26 includes a first base 260; the first base 260 has eight hollow elastic suction nozzles 261 arranged in sequence (preferably 1-20 in number), the eight elastic suction nozzles 261 can be interference fit with the pipette connecting end of the suction tip 3 arranged in the above-mentioned twelve strip-shaped through grooves 10, and the center distance between adjacent elastic suction nozzles 261 is the same as the center distance between adjacent strip-shaped through grooves 10; the first base 260 has four through grooves 262 connected to the inner cavity of the elastic suction nozzles 261, and each through groove 262 corresponds to the inner cavity connected to two elastic suction nozzles 261; the first base 260 has four evenly distributed A first through hole 263 passes through the first through hole 263 along the width direction thereof, and four first guide rods 22 extend into the first through holes 263 respectively to connect all twelve suction head inserts 26, and a plurality of second springs 264 are arranged between adjacent suction head inserts 26; the second springs 264 have an extended state and a compressed state, and when in the extended state, the two ends of two adjacent suction head inserts 26 are respectively kept at a set distance by the limit members 25, and when in the compressed state, the center distance between the two adjacent aligned elastic suction nozzles 261 of the two adjacent suction head inserts 26 is equal to the center distance between the adjacent suction heads 3 arranged in the same strip-shaped through groove 10.

[0043] Both ends of the pipette tip insert 26 in the length direction have a stopper fitting structure 265, and both ends of the first base 260 of two adjacent pipette tip inserts 26 in the length direction are fitted with a stopper 25 through the stopper fitting structure 265. Specifically, the stopper fitting structure 265 is a groove, and the stopper 25 includes two parallel stopper walls 251 and a connecting wall 252 connecting the two stopper walls 251. The two stopper walls 251 are respectively fitted and overlapped with one side wall of the groove of the first base 260 of the two adjacent pipette tip inserts 26. Further, the two stopper walls 251 of each stopper 25 have corresponding third through holes 250, and a third guide rod 24 extends into the third through holes 250 of the eleven stopper 25 to connect the eleven stopper 25.

[0044] Each suction head pusher 27 includes a second base 270; the second base 270 has four push plates 271 that can be inserted into the four-way groove 262 of the first base 260; the second base 270 has four second through holes 273 extending along the width direction thereof, and the four second guide rods 23 respectively extend into the second through holes 273 to connect all twelve suction head pushers 27, and a third spring 274 is provided between adjacent suction head pushers 27; the third spring 274 makes the change of the distance between two adjacent suction head pushers 27 adapt to the change of the distance between two adjacent suction head inserts 26

[0045] The suction tip insert 26 and the suction tip pusher 27 are connected by a plurality of first springs 28. Figure 5 and 6 As shown, the first spring 28 has an extended state and a compressed state. When in the extended state, the push plate 271 extends into the through slot 262 but does not extend into the inner cavity of the elastic suction nozzle 261. When in the compressed state, the push plate 271 extends into the inner cavity of the elastic suction nozzle 261 through the through slot 262 and penetrates the side wall of the elastic suction nozzle 261 to push out the suction tip 3 that is interference fit in the elastic suction nozzle 261 and place the suction tip 3 in the suction tip box.

[0046] After the tip insert 26, the tip pusher 27, the stopper 25, the first to third guide rods 22, 23 and 24 are assembled, they are clamped by the two clamping plates 21. The two clamping plates 21 are respectively provided with first to third openings 210, 211 and 213 adapted to the first to third guide rods 22, 23 and 24, and the second opening 211 is in a strip shape to adapt to the displacement of the second guide rod 23 with the tip pusher 27 relative to the tip insert 26. Preferably, the first to third stoppers 220, 230 and 24 are provided at both ends of the first to third guide rods 22, 23 and 24 to prevent the first to third guide rods 22, 23 and 24 from separating from the two clamping plates 21.

[0047] During use, the second clamping plate 21 is pressed so that the second spring 264 and the third spring 274 are both in a compressed state. At this time, the center distance between the two adjacent elastic suction nozzles 261 of the two adjacent suction head inserts 26 is equal to the center distance between the adjacent suction heads 3 arranged in the same strip-shaped through groove 10. This is to align the elastic suction nozzle 261 of the suction head transfer and loading mechanism 2 with the suction head 3 on the porous sieve plate 1 and press lightly to embed the suction head 3 on the porous sieve plate 1 into the elastic suction nozzle 261; then release the second clamping plate 21 to allow the second suction head 3 to be inserted into the elastic suction nozzle 261. The spring 264 and the third spring 274 are in an extended state, and the distance between two adjacent tip inserts 26 is limited by the limiter 25 and is in a distance that matches the tip box. Then, the tip transfer and loading mechanism 2 is picked up, and the tip 3 is aligned with the hole on the tip box. The tip pusher 27 is immediately pushed to compress the first spring 28. The push plate 271 extends into the inner cavity of the elastic nozzle 261 and penetrates the side wall of the elastic nozzle 261, pushing the tip 3 from the elastic nozzle 261 and dropping it into the tip box, completing the loading of the tip 3.

[0048] The above description is only a preferred embodiment of the present invention, and therefore cannot be used to limit the scope of the present invention. That is, equivalent changes and modifications made according to the patent scope of the present invention and the contents of the specification should still fall within the scope of the present invention.

Claims

1. A device for quickly loading and unloading pipette tips, characterized in that: include: A porous sieve plate having a plurality of strip-shaped through grooves of the same size and arranged in parallel, so that the bulk pipette tips are regularly arranged vertically along the length direction of the plurality of strip-shaped through grooves, and the pipette connecting ends of the pipette tips face upward, the liquid aspirating ends of the pipette tips face downward, and the edges of the pipette connecting ends of adjacent pipette tips contact each other; A tip transfer and loading mechanism, used for transferring the tips on the porous screen plate to the tip box, comprising at least one tip insert and at least one tip pusher adapted to the tip insert; The tip insert comprises a first base; the first base has a plurality of hollow elastic suction nozzles arranged in sequence and a plurality of first through holes penetrating along the width direction thereof, the plurality of elastic suction nozzles can be interference fit with the pipette connecting ends of the suction nozzles arranged in the above-mentioned strip-shaped through grooves, and the center distance between adjacent elastic suction nozzles is the same as the center distance between adjacent strip-shaped through grooves, and the center distance between adjacent strip-shaped through grooves in the length direction is equal to the center distance between the suction tip holes in the length direction of the suction tip box; the first base also has at least one through groove communicating with the inner cavity of the elastic suction nozzle; The suction head pusher comprises a second base; the second base has at least one push plate which can extend into at least one through slot of the first base; The tip insert and the tip pusher are connected by at least one first elastic member, and the first elastic member has an extended state and a compressed state. When in the extended state, the push plate extends into the through slot but does not extend into the inner cavity of the elastic nozzle. When in the compressed state, the push plate extends into the inner cavity of the elastic nozzle through the through slot and penetrates the side wall of the elastic nozzle to push out the tip that is interference-fitted with the elastic nozzle and place the tip in the tip box. A plurality of first guide rods and at least one limiting member; the first guide rods extend into the first through hole to connect at least two suction head inserts, and a second elastic member is provided between adjacent suction head inserts; the second elastic member has an extended state and a compressed state, when in the extended state, two adjacent suction head inserts maintain a set spacing through at least one limiting member, and when in the compressed state, the center distance between two adjacent aligned elastic suction nozzles of two adjacent suction head inserts is equal to the center distance between adjacent suction heads arranged in the same strip through groove.

2. A pipette tip rapid box loading device as claimed in claim 1, characterized in that: The number of the strip-shaped through grooves is 5-50, the length is 5-100 cm, and the width is 3-20 mm.

3. A pipette tip rapid box loading device as claimed in claim 1, characterized in that: Both ends of the pipette tip embedding component in the length direction are provided with a limit piece matching structure, and both ends of the first base of two adjacent pipette tip embedding components in the length direction are respectively matched with a limit piece through the limit piece matching structure.

4. A pipette tip rapid box loading device as claimed in claim 3, characterized in that: The limiting member adapting structure is a groove, and the limiting member includes two parallel limiting walls and a connecting wall connecting the two limiting walls, and the two limiting walls are respectively adapted and overlapped with one side wall of the groove of the first base of two adjacent suction head inserts.

5. A pipette tip rapid box loading device as claimed in claim 1, characterized in that: It also includes a plurality of second guide rods, the second base of the tip pusher has a plurality of second through holes extending therethrough along its width direction, the second guide rods extend into the second through holes to connect at least two tip pushers, and a third elastic member is provided between adjacent tip pushers; the third elastic member enables the change in the spacing between two adjacent tip pushers to adapt to the change in the spacing between two adjacent tip inserts.

6. A pipette tip rapid box loading device according to any one of claims 1 to 5, characterized in that: The number of the suction tip inserts is 1-20.

7. A pipette tip rapid box loading device according to any one of claims 1 to 5, characterized in that: The porous sieve plate is made of metal, plastic or glass.

8. A pipette tip rapid box loading device according to any one of claims 1 to 5, characterized in that: The number of the elastic suction nozzles of the suction head insert is 1-20.

Images