An animal rotation impact injury testing system
By designing an animal rotation impact injury test system to simulate animal rotation impact, the problem of lack of DAI research model in the existing technology is solved, effective experimental data is provided, and the research and treatment of DAI diseases is promoted.
Patent Information
- Application Number
- CN202111356251.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2021-11-16
- Publication Date
- 2025-07-25
- Estimated Expiration
- 2041-11-16
AI Technical Summary
The lack of effective animal models in the prior art to study diffuse axonal injury (DAI), resulting in insufficient research data and difficulty in preventing or treating the disease.
An animal rotation impact injury test system is designed, including a load-bearing assembly, a launching device and an impact seat. The launching device causes the load-bearing assembly to rotate and fire along the launching track, simulating the animal rotation impact and generating diffuse axonal damage (DAI) state.
Suitable animal model data are provided to help improve the understanding of DAI diseases and are conducive to prevention and treatment.
Smart Images

Figure CN114052976B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the field of impact testing, and particularly to an animal rotational impact injury testing system. Background Art
[0002] Diffuse axonal injury (DAI) is a type of craniocerebral injury where external trauma causes rotational acceleration and / or angular acceleration of the brain, resulting in shear forces within the brain tissue, leading to damage to nerve axons and small blood vessels. This can cause the patient to fall into a coma or even die. Patients typically present with moderate to deep coma lasting more than 12 hours, often accompanied by mild changes in vital signs such as a slow heart rate, elevated blood pressure, and slowed breathing, severely affecting the patient's life and future. Diagnosis of this type of craniocerebral injury requires relatively advanced imaging examinations, and there is usually a long time interval from the occurrence to the diagnosis. In order to study
[0003] Since the incidence of this type of craniocerebral injury is relatively low and the research data is not as abundant as that of other trauma studies, during the research process, it is necessary to establish a relatively complete pathogenic mechanism or animal model for research, which is beneficial for the prevention, treatment, and nursing of this disease and for improving the overall understanding of the disease. Summary of the Invention
[0004] Aiming at the deficiencies of the existing technology, the technical problem to be solved by the present invention is to provide an animal rotational impact injury testing system that can make the animal rotate and be impacted, providing appropriate research data for corresponding diseases.
[0005] To achieve the above object, the present invention is implemented through the following technical solutions: An animal rotational impact injury testing system, comprising:
[0006] A loading component for loading and fixing the animal;
[0007] A launching device provided with a launching track, with a launching port at the end of the launching track. The loading component is located within the launching track, and the launching device can drive the loading component to move along the launching track while rotating, causing the loading component to be launched out of the launching port in a rotating state; and
[0008] An impact seat provided on one side of the launching port and in the tangential direction of the launching port.
[0009] Further, the loading component includes a loading block and fixing straps. There are multiple fixing straps, and the multiple fixing straps are arranged on the top of the loading block for fixing the animal on the loading block.
[0010] Further, the launching device includes a rotary power source and a rotary guiding track. The launching track is the rotary guiding track, and the rotary guiding track is spiral. The launching port is located at the tail end of the rotary guiding track. The head end of the rotary guiding track is connected to the rotary power source. A plurality of internal teeth are arranged at intervals along the extending direction on the inner wall of the rotary guiding track. A plurality of external teeth are arranged on the outer wall of the bearing block. During the process of the bearing block moving along the rotary guiding track, the bearing block rolls and meshes with the internal teeth through the external teeth.
[0011] Further, the rotary guiding track is a tower-shaped spiral track extending along the axial direction of the rotary power source, and the power output end of the rotary power source extends vertically downward.
[0012] Further, the rotary guiding track includes a bottom plate and a side plate. The side plate is in an upright state and spirally winds along the axial direction of the rotary power source. The bottom plate is arranged at the bottom of the side plate and extends along the extending direction of the side plate. A T-shaped chute is formed on the bottom plate along its extending direction. A T-shaped slider is arranged on the bottom surface of the bearing block, and the T-shaped slider can roll and slide and is inserted into the T-shaped chute.
[0013] Further, a plurality of rolling balls are embedded on the outer wall of the T-shaped slider, and the rolling balls are in contact with the inner wall of the T-shaped chute.
[0014] Further, the impact seat includes a mounting table and an impact block. The mounting table is provided with a mounting groove along the tangential direction of the launching port, and the impact block is located in the mounting groove.
[0015] Further, a locking member is further arranged on the impact seat. A through groove is formed on the side wall of the mounting table along the extending direction of the mounting groove, and the through groove communicates with the mounting groove. The locking member includes a screw and a locking nut. The screw is arranged on the impact block and passes through the through groove, and the locking nut is threadedly connected to the screw.
[0016] Advantages of the present invention:
[0017] The above animal rotary impact injury test system includes a bearing assembly, a launching device and an impact seat. The bearing assembly is used for bearing and fixing an animal. A launching track is arranged on the launching device, and a launching port is arranged at the end of the launching track. The bearing assembly is located in the launching track. The launching device can drive the bearing assembly to move along the launching track and rotate at the same time, so that the bearing assembly is launched from the launching port in a rotating state. The impact seat is arranged on one side of the launching port and is located in the tangential direction of the launching port.
[0018] In use, place the bearing block at the head end of the rotary guiding track. Subsequently, start the rotary power source, which drives the rotary guiding track to rotate. Under the action of centrifugal force, the bearing block moves along the rotary guiding track, and the side wall of the bearing block always abuts against the inner wall of the rotary guiding track. At this time, the angular velocity of the revolution of the bearing block is equal to the angular velocity of the rotary power source. Meanwhile, under the action of the external teeth and internal teeth, the bearing block rotates rapidly, so that the bearing block is in a rapid rotation state and drives the animal on the bearing block to rotate at high speed. When the bearing block is launched from the launch port, the bearing block is launched in a rotating state, so that the animal impacts the impact seat in a rotating state, which can cause the experimental animal to be in a coma state of diffuse axonal injury (DAI). Then, anatomically and pathologically examine the animal or perform imaging examinations to determine the occurrence of diffuse axonal injury (DAI), conduct research on the experimental animal, improve the overall understanding of the disease, and contribute to the prevention or treatment and nursing of the disease. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] In order to more clearly illustrate the specific embodiments of the present invention, the drawings required for the specific embodiments will be briefly introduced below. In all the drawings, the elements or parts are not necessarily drawn to actual scale.
[0020] Figure 1 Schematic diagram of an animal rotation impact injury test system provided by an embodiment of the present invention;
[0021] Figure 2 is Figure 1 Local schematic diagram at A in
[0022] Figure 3 is Figure 1 Schematic diagram at the launch port of an animal rotation impact injury test system shown in
[0023] Figure 4 is Figure 1 Schematic diagram of the bearing assembly in an animal rotation impact injury test system shown in
[0024] Figure 5 is Figure 1 Schematic diagram of the impact seat in an animal rotation impact injury test system shown in
[0025] Reference numerals:
[0026] 100, bearing assembly; 110, bearing block; 111, external teeth; 112, T-shaped slider; 113, ball; 120, fixing band;
[0027] 200. Launch device; 210. Rotary power source; 220. Rotary guiding track; 221. Bottom plate; 222. Side plate; 223. T-shaped sliding groove; 230. Launch port; 240. Internal teeth.
[0028] 300. Impact seat; 310. Installation table; 311. Installation groove; 320. Impact block; 330. Locking member; 331. Screw; 332. Locking nut. Detailed implementation manner
[0029] Hereinafter, embodiments of the technical solution of the present invention will be described in detail with reference to the drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present invention, and therefore are only examples and cannot be used to limit the protection scope of the present invention.
[0030] Please refer to Figures 1 to 5 , the present invention provides an animal rotary impact injury test system, including a bearing assembly 100, a launch device 200 and an impact seat 300. It can cause animals to generate simulated diffuse axonal injury, provide appropriate animal model data for corresponding diseases, and facilitate subsequent research.
[0031] Specifically, the bearing assembly 100 is used to bear and fix animals. In this embodiment, the bearing assembly 100 includes a bearing block 110 and fixing straps 120. There are multiple fixing straps 120, and the multiple fixing straps 120 are arranged on the top of the bearing block 110 for fixing animals on the bearing block 110. In specific implementation, the fixing strap 120 can be fixed at one end on the bearing block 110 and the other end can be hung or clamped with the bearing block 110, so that the experimental animal can be fixed on the bearing block 110; in addition, the fixing strap 120 can also be a rope. When in use, the animal is placed on the bearing block 110, and the animal can also be tied to the bearing block 110 with a rope.
[0032] A launch track is provided on the launch device 200, a launch port 230 is provided at the end of the launch track, the bearing assembly 100 is located in the launch track, and the launch device 200 can drive the bearing assembly 100 to move along the launch track and rotate at the same time, so that the bearing assembly 100 is launched from the launch port 230 in a rotating state. The impact seat 300 is arranged on one side of the launch port 230 and is located in the tangential direction of the launch port 230.
[0033] Specifically, the launching device 200 includes a rotary power source 210 and a rotary guiding track 220. The launching track is the rotary guiding track 220, and the rotary guiding track 220 is spiral in shape. The launching port 230 is located at the tail end of the rotary guiding track 220. The head end of the rotary guiding track 220 is connected to the rotary power source 210. A plurality of internal teeth 240 are arranged at intervals along the extending direction on the inner wall of the rotary guiding track 220. A plurality of external teeth 111 are arranged on the outer wall of the bearing block 110. During the movement of the bearing block 110 along the rotary guiding track 220, the bearing block 110 rolls and meshes with the internal teeth 240 through the external teeth 111.
[0034] In use, the bearing block 110 is placed at the head end of the rotary guiding track 220. Subsequently, the rotary power source 210 is started, driving the rotary guiding track 220 to rotate. Under the action of centrifugal force, the bearing block 110 moves along the rotary guiding track 220, and the side wall of the bearing block 110 always abuts against the inner wall of the rotary guiding track 220. At this time, the angular velocity of the revolution of the bearing block 110 is equal to the angular velocity of the rotary power source 210. At the same time, under the action of the external teeth 111 and the internal teeth 240, the bearing block 110 is driven to rotate rapidly, so that the bearing block 110 is in a rapid rotation state, driving the animals on the bearing block 110 to rotate at a high speed. When the bearing block 110 is launched from the launching port 230, the bearing block 110 is launched in a rotating state, so that the animals impact on the impact seat 300 in a rotating state, which can cause a coma state of diffuse axonal injury (DAI) in the experimental animals. Then, the animals are subjected to anatomical pathological examination or imaging examination to determine the occurrence of diffuse axonal injury (DAI), and research is carried out on the experimental animals to improve the overall understanding of the disease, which is beneficial to the prevention or treatment and nursing of the disease.
[0035] During the movement of the bearing block 110, the angular velocity of the self-rotation of the bearing block 110 at a certain time is the linear velocity of the bearing block 110 at this time divided by the revolving radius at this time. In this embodiment, since the rotary guiding track 220 is spiral in shape, the diameter of the rotary guiding track 220 gradually increases. When the bearing block 110 moves along the rotary guiding track 220, its revolving radius becomes larger and larger. With the angular velocity remaining unchanged, the linear velocity of the bearing block 110 becomes larger and larger. Finally, the self-rotation angular velocity of the bearing block 110 becomes larger and larger, so that the bearing block 110 is launched at a relatively high rotation speed.
[0036] In specific implementation, the rotational power source 210 is a rotary electric machine in the prior art or can also be an artificial rotation method. When it is necessary to change the launching speed of the bearing block 110, only the rotational speed of the rotational power source 210 needs to be changed, and the adjustment method is convenient and simple. At the same time, a speed detector can be arranged at the end of the launching port 230 to test the rotational speed of the bearing block 110 through the speed detector, which is further conducive to research and learning.
[0037] The rotary guiding track 220 can be a planar spiral shape or a three-dimensional spiral shape. Preferably, the rotary guiding track 220 is a tower-shaped spiral track extending along the axial direction of the rotational power source 210, and the power output end of the rotational power source 210 extends vertically downward. Since it is a three-dimensional spiral shape, during the movement process, gravity can provide part of the downward driving force for the bearing block 110, thereby accelerating the revolution speed of the bearing block 110.
[0038] As a more optimal implementation manner, the rotary guiding track 220 includes a bottom plate 221 and a side plate 222. The side plate 222 is in an erected state and spirally winds along the axial direction of the rotational power source 210. The bottom plate 221 is arranged at the bottom of the side plate 222 and extends along the extending direction of the side plate 222. A T-shaped sliding groove 223 is formed on the bottom plate 221 along its extending direction. A T-shaped sliding block 112 is arranged on the bottom surface of the bearing block 110, and the T-shaped sliding block 112 can be inserted into the T-shaped sliding groove 223 in a rolling and sliding manner. Through the limitation of the T-shaped sliding groove 223, the bearing block 110 can be prevented from jumping up and down, so that the movement of the bearing block 110 is more stable.
[0039] Furthermore, a plurality of rolling balls 113 are embedded on the outer wall of the T-shaped sliding block 112, and the rolling balls 113 are in contact with the inner wall of the T-shaped sliding groove 223. Through the rolling balls 113, the friction between the T-shaped sliding block 112 and the T-shaped sliding groove 223 can be reduced.
[0040] In this embodiment, the impact seat 300 includes a mounting table 310 and an impact block 320. The mounting table 310 is provided with a mounting groove 311 along the tangent direction of the launching port 230, and the impact block 320 is located in the mounting groove 311. The impact block 320 is used to withstand the impact of animals. During use, different materials of the impact block 320, such as hard materials or soft materials, can be selected according to the usage situation. During use, the impact block 320 is slid along the mounting groove 311 to change the impact distance of the animals, so as to obtain different impact effects.
[0041] In addition, a locking member 330 is also provided on the impact seat 300. A through groove is formed in the side wall of the mounting table 310 along the extending direction of the mounting groove 311, and the through groove communicates with the mounting groove 311. The locking member 330 includes a screw 331 and a locking nut 332. The screw 331 is provided on the impact block 320 and passes through the through groove. The locking nut 332 is threadedly connected to the screw 331. By locking with the locking member 330, displacement of the impact block 320 during impact can be prevented, thereby changing the impact effect.
[0042] The usage method of the above animal rotational impact injury test system is as follows:
[0043] During use, first fix the animal on the bearing block 110 with a fixing strap, then place the bearing block 110 at the head end of the rotary guide track 220. Subsequently, the rotary power source 210 is started, and the bearing block 110 is launched along the rotary guide track 220 in a rotating state, so that the animal impacts on the impact seat 300 in a rotating state, enabling the experimental animal to form a coma state of diffuse axonal injury (DAI). Then, the animal is subjected to anatomical pathological examination or imaging examination to determine the occurrence of diffuse axonal injury (DAI), and research is carried out on this experimental animal to improve the overall understanding of this disease, which is beneficial to the prevention or treatment and nursing of this disease.
[0044] During the use process, different rotation speeds can be obtained by changing the rotation speed of the rotary power source 210; different impact effects can also be obtained by using impact blocks 320 with different shapes and different materials; at the same time, the distance between the impact block 320 and the launch port 230 can also be changed to obtain different impact effects.
[0045] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and the description of the present invention.
Claims
1. An animal rotation impact injury testing system, characterized in that, Comprising: A bearing assembly for bearing and fixing an animal; A launching device, on which a launching track is provided, a launching port is provided at the end of the launching track, the bearing assembly is located within the launching track, and the launching device can drive the bearing assembly to move along the launching track while rotating, so that the bearing assembly is launched out from the launching port in a rotating state; and An impact seat, provided on one side of the launching port and in the tangential direction of the launching port, the bearing assembly includes a bearing block and fixing straps, there are multiple fixing straps, and the multiple fixing straps are arranged on the top of the bearing block for fixing the animal on the bearing block; The launching device includes a rotational power source and a rotational guiding track, the launching track is the rotational guiding track, and the rotational guiding track is in a spiral shape, the launching port is located at the end of the rotational guiding track, the head end of the rotational guiding track is connected to the rotational power source, multiple internal teeth are arranged at intervals along the extending direction on the inner wall of the rotational guiding track, external teeth are provided on the outer wall of the bearing block, and during the movement of the bearing block along the rotational guiding track, the bearing block rolls and meshes with the internal teeth through the external teeth; The rotational guiding track is a tower-shaped spiral track extending along the axial direction of the rotational power source, and the power output end of the rotational power source extends vertically downward; The rotational guiding track includes a bottom plate and side plates, the side plates are in an upright state and are spirally coiled along the axial direction of the rotational power source, the bottom plate is arranged at the bottom of the side plates and extends along the extending direction of the side plates, a T-shaped sliding groove is opened on the bottom plate along its extending direction, a T-shaped sliding block is provided on the bottom surface of the bearing block, and the T-shaped sliding block can roll and slide and is inserted into the T-shaped sliding groove.
2. The animal rotation impact injury testing system according to claim 1, characterized in that, Multiple rollable balls are embedded on the outer wall of the T-shaped sliding block, and the balls are in contact with the inner wall of the T-shaped sliding groove.
3. The animal rotation and impact injury testing system according to claim 1, wherein The impact seat includes a mounting table and an impact block, the mounting table is provided with a mounting groove along the tangential direction of the launching port, and the impact block is located within the mounting groove.
4. The animal rotation and impact injury testing system according to claim 3, wherein A locking member is further provided on the impact seat, a through groove is opened on the side wall of the mounting table along the extending direction of the mounting groove, and the through groove communicates with the mounting groove, the locking member includes a screw and a locking nut, the screw is provided on the impact block and passes through the through groove, and the locking nut is threadedly connected to the screw.
Citation Information
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