Reagent sequential mixing reaction and automatic detection equipment controlled by centrifugal force

Abstract

The present invention relates to a reagent sequential mixing reaction and automatic detection device controlled by centrifugal force. The reaction tube is fixedly arranged in an inclined reaction tube placement groove through a reaction tube fixing buckle. A detection integrated upper cover is arranged between the reaction tube and the reaction tube fixing buckle. After the mixing reaction device drives the rotation of the reaction tube, under the action of centrifugal force, the mixed reagents in the reaction tube are mixed and reacted in sequence. At the same time, the detection integrated upper cover detects the mixed reagents in the reaction tube. And through the setting of the electronic control box on the top surface of the sealing cover, the transmitted light and reflected light of the LED light source in the photoelectric detection device after irradiating the mixed chemical reagents in the reaction tube received by the photoelectric detection device are synchronously converted into optical signals, and are uploaded to the mobile device through the wireless communication module, so as to detect the reagents in the reaction container during the process of sequential mixing of the reagents.

Description

Technical Field

[0001] The present invention relates to the technical field of chemical mixing equipment, and particularly to a reagent sequential mixing reaction and automatic detection device controlled by centrifugal force. Background Art

[0002] When performing reagent detection in the prior art, corresponding reaction reagents and sample reagents are usually placed in a reaction container and stirred to mix the solution to make it react fully. The degree of solution mixing determines the accuracy of the detection result. Usually, in order to accelerate the mixing rate of the solution, a reagent mixing device is generally used to quickly shake the reagents in the reaction container. The mixing method of the existing reagent mixing device is relatively single.

[0003] In the patent document: CN201620171971.7, the reagent cup and the turntable installed on the conductive slip ring are driven to rotate by a hollow shaft motor, which speeds up the mixing speed of some solutions placed in the reagent cup and improves the working efficiency. However, after the solution in the reagent cup is mixed, the mixed solution needs to be added into a chemical vessel for sampling and detection of the mixed solution, and it is impossible to detect the reagents in the reaction container during the reaction process of the mixed solution. Summary of the Invention

[0004] In order to solve the above problems, the present invention provides a reagent sequential mixing reaction and automatic detection device controlled by centrifugal force, which can control the sequential mixing of reagents in a reaction container by centrifugal force and can detect the reagents in the reaction container during the sequential mixing process of the reagents.

[0005] In order to achieve the above object, the reagent sequential mixing reaction and automatic detection device designed by the present invention mainly includes a mixing reaction device. At least one obliquely arranged reaction tube placement groove is provided on the top surface of the mixing reaction device. A hinge is provided inside the reaction tube placement groove, and a reaction tube fixing buckle is connected to the hinge. A positioning groove hole is provided in the reaction tube fixing buckle, and an integrated detection upper cover is provided in the positioning groove hole. The distance from the notch of the reaction tube placement groove to the central axis of the top surface of the mixing reaction device is greater than the distance from the bottom of the reaction tube placement groove to the central axis of the top surface of the mixing reaction device. This structure controls the flow direction of the reagent during the rotation of the mixing reaction device through the obliquely arranged reaction tube placement groove, ensures that the reagents are mixed and reacted in sequence, and detects the mixed reagent in the reaction tube through the integrated detection upper cover provided in the reaction tube fixing buckle after sufficient mixing and reaction.

[0006] A further solution is to configure the integrated detection cover to include a sealing cover and a photoelectric detection device. The top surface of the sealing cover houses an electrical control box that switches the photoelectric detection device on and off. The photoelectric detection device is fixedly mounted on the side of the sealing cover facing the reaction tube placement slot. The detection optical path within the photoelectric detection device is arranged perpendicularly to the horizontal plane of the mixing reaction device. The electrical control box engages with the positioning slots and clips onto the reaction tube securing buckle. This structure facilitates installation and removal of the integrated detection cover by directly clipping the electrical control box onto the reaction tube securing buckle.

[0007] A further embodiment is that the photoelectric detection device comprises a photoelectric sensor, a light source, and a fixed housing. The fixed housing is fixedly mounted on the side of the sealing cover facing the reaction tube slot. A detection cavity is defined on one side of the fixed housing. A photoelectric sensor and a light source are embedded and fixedly mounted on either side of the detection cavity. The angle between the light path between the light source and the photoelectric sensor and the side of the sealing cover facing the reaction tube slot is less than 90 degrees. This structure, by aligning the light path with the bottom surface of the sealing cover with the tilted position of the reaction tube, ensures that light can be incident vertically on the mixed chemical reagents in the reaction tube during its rotation.

[0008] A further embodiment is described in which a reaction tube is placed in the reaction tube storage slot, a sealing cover is provided above the reaction tube to prevent the reagent in the reaction tube from being thrown out due to centrifugal force, and a photoelectric detection device is located inside the reaction tube. The reaction tube securing buckle has an L-shaped connecting piece on one end that cooperates with the upper surface of the integrated detection cover for position retention, and a J-shaped undercut on the other end that cooperates and fastens with the centrifugal bracket. This structure secures the reaction tube in the reaction tube storage slot via the L-shaped connecting piece and the J-shaped undercut.

[0009] A further solution is that a wireless communication module for transmitting optical signals is provided in the electric control box. This structure uploads the data detected by the photoelectric detection device to the mobile device via the wireless communication module in the electric control box.

[0010] The reagent sequential mixing reaction and automatic detection equipment designed by the present invention is controlled by centrifugal force. The reaction tube is fixed in an oblique reaction tube placement groove by a reaction tube fixing buckle. An integrated detection cover is provided between the reaction tube and the reaction tube fixing buckle. After the reaction tube is driven to rotate by the mixing reaction device, the mixed reagents in the reaction tube are mixed and reacted in sequence under the action of centrifugal force. At the same time, the mixed reagents in the reaction tube are detected by the integrated detection cover. Through the setting of the electric control box on the top surface of the sealing cover, the transmitted light received by the photoelectric detection device from the LED light source in the photoelectric detection device after irradiating the mixed chemical reagents in the reaction tube is converted into an optical signal, and uploaded to the mobile device through the wireless communication module, thereby detecting the reagents in the reaction container during the process of sequential mixing of the reagents. BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Figure 1 This is an axonometric diagram of a reagent sequential mixing reaction and automatic detection device controlled by centrifugal force.

[0012] Figure 2 This is a schematic diagram of the detection of mixed reagents in the reaction tube described in Example 1. DETAILED DESCRIPTION

[0013] In order to further illustrate the technical means and effects adopted by the present invention to achieve the predetermined purpose of the invention, the specific implementation methods, structures, features and effects of the present invention are described in detail below in conjunction with the accompanying drawings and preferred embodiments.

[0014] Example 1.

[0015] like Figure 1 As shown, the reagent sequential mixing reaction and automatic detection equipment controlled by centrifugal force described in this embodiment mainly includes a mixing reaction device 1, the top surface of the mixing reaction device 1 is provided with at least one obliquely arranged reaction tube placement groove 2, a reaction tube 3 is placed in the reaction tube placement groove 2, and an integrated detection cover 4 is provided above the reaction tube 3 to prevent the reagent in the reaction tube 3 from being thrown out due to centrifugal force. The distance from the tube mouth of the reaction tube 3 to the central axis of the top surface of the mixing reaction device 1 is greater than the distance from the bottom of the reaction tube 3 to the central axis of the top surface of the mixing reaction device 1.

[0016] A hinge is provided on the top surface of the mixing reaction device 1, and a reaction tube fixing buckle 8 is connected to the hinge. A positioning slot is provided in the reaction tube fixing buckle 8, and the positioning slot is engaged with the detection integrated upper cover 4. One end of the reaction tube fixing buckle 8 is provided with an L-shaped connecting piece 9 that cooperates with the upper surface of the detection integrated upper cover 5 to limit the position, and the other end is provided with a J-shaped inverted buckle 10 that cooperates and fastens with the centrifugal bracket.

[0017] The integrated detection cover 4 is divided into a sealing cover 5 and a photoelectric detection device 6. The top surface of the sealing cover 5 controls the electrical control box 7 for switching the photoelectric detection device 6. The photoelectric detection device 6 is fixedly arranged on the side of the sealing cover 5 facing the reaction tube placement slot 2. The photoelectric detection device 6 is located on the inner side of the reaction tube 3. The detection light path in the photoelectric detection device 6 is vertically arranged on the horizontal plane of the mixing reaction device 1, and the photoelectric detection device 6 is divided into a photoelectric sensor 11, a light source 12 and a fixed shell 13. The fixed shell 13 is fixedly arranged on the side of the sealing cover 5 facing the reaction tube placement slot 2. A detection cavity 14 is opened on one side of the fixed shell 13. The photoelectric sensor 11 and the light source 12 are embedded and fixed in the detection cavity 14, and the angle between the light path between the light source 12 and the photoelectric sensor 11 and the side of the sealing cover 5 facing the reaction tube placement slot 2 is less than 90 degrees, and a wireless communication module for transmitting optical signals is provided in the electrical control box 7.

[0018] like Figure 1 andFigure 2 As shown, the working process of the reagent sequential mixing reaction and automatic detection equipment controlled by centrifugal force is as follows:

[0019] First, the reaction tube 3 containing the sample reagent and the reaction reagent is placed in the reaction tube placement slot 3 arranged obliquely in the mixing reaction device 1, and the plane where the reaction reagent in the reaction tube is located is higher than the plane where the sample reagent is located;

[0020] Connect the positioning slots in the L-shaped connecting piece 9 to the electrical control box 7 on the upper portion of the integrated detection cover 4, and simultaneously secure the J-shaped undercut 10 to the side wall of the centrifugal support 1;

[0021] The mixing reaction device 1 drives the reaction tube 4 in the reaction tube placement tank 3 to perform non-uniform circular motion;

[0022] By increasing the rotation speed of the reaction tube 4, the sample reagent in the reaction tube 4 flows toward the photoelectric detection device 6;

[0023] The sample reagent and the reaction reagent in the reaction tube 4 are fully integrated to ensure that the sample reagent and the reaction reagent are fully mixed and reacted;

[0024] When the mixed chemical reagents in the reaction tube 4 are completely immersed in the photoelectric detection device 6, the mixed reagents in the reaction tube 4 are detected by the photoelectric detection device 6;

[0025] The detected data signal is uploaded to the mobile device through the wireless communication module in the electric control box 7.

[0026] The above description is merely a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as above in terms of a preferred embodiment, it is not intended to limit the present invention. Any person skilled in the art can, without departing from the scope of the technical solution of the present invention, make some changes or modifications to equivalent embodiments using the technical contents disclosed above. However, any brief modifications, equivalent changes and modifications made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention are still within the scope of the technical solution of the present invention.

Claims

1. A reagent sequential mixing reaction and automatic detection device controlled by centrifugal force, mainly comprising a mixing reaction device (1), characterized in that The top surface of the mixing reaction device (1) is provided with at least one reaction tube placement groove (2) arranged obliquely, a hinge is provided on the inner side of the reaction tube placement groove (2), a reaction tube fixing buckle (8) is connected to the hinge, a detection integrated upper cover (4) is provided on the reaction tube fixing buckle (8), and the distance from the groove opening of the reaction tube placement groove (2) to the central axis of the top surface of the mixing reaction device (1) is greater than the distance from the groove bottom of the reaction tube placement groove (2) to the central axis of the top surface of the mixing reaction device (1); the detection integrated upper cover (4) is divided into a sealing cover (5) and a photoelectric detection device (6), the sealing cover (5) is fixed with the reaction tube fixing buckle (8) through a positioning slot hole provided on the reaction tube fixing buckle (8), an electric control box (7) for controlling the photoelectric detection device (6) is provided on the sealing cover (5), and the photoelectric detection device (6) is fixedly provided on the side of the sealing cover (5) facing the reaction tube placement groove (2).

2. The reagent sequential mixing reaction and automatic detection device controlled by centrifugal force according to claim 1, wherein The photoelectric detection device (6) is divided into a photoelectric sensor (11), a light source (12) and a fixed shell (13). The fixed shell (13) is fixedly arranged on a side of the sealing cover (5) facing the reaction tube placement groove (2). A detection cavity (14) is opened on one side of the fixed shell (13). The photoelectric sensor (11) and the light source (12) are embedded and fixedly arranged in the detection cavity (14). The angle between the detection light path between the light source (12) and the photoelectric sensor (11) and the side of the sealing cover (5) facing the reaction tube placement groove (2) is less than 90 degrees.

3. The reagent sequential mixing reaction and automatic detection device controlled by centrifugal force according to claim 1 or 2, characterized in that A reaction tube (3) is placed in the reaction tube placement groove (2), and the tube mouth of the reaction tube (3) cooperates with the detection integrated upper cover (4). One end of the reaction tube fixing buckle (8) is provided with an L-shaped connecting piece (9) that cooperates with the upper surface of the detection integrated upper cover (4) for limiting the position, and the other end is provided with a J-shaped buckle (10) that cooperates and fastens with the centrifugal bracket.

4. The reagent sequential mixing reaction and automatic detection device controlled by centrifugal force according to claim 3, wherein The electric control box (7) is provided with a wireless communication module for transmitting optical signals.

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