Artificial lung

Abstract

The second lid member (36) that constitutes the outer shell (26) of the artificial lung (10) has a second concave wall portion (88) that is recessed toward the gas exchange portion (30) side with respect to the inner surface (74a) of the second lid main body (74). A pressure adjustment hole (86) is formed in the second lid main body (74), and a sampling port (90a) for collecting the gas led out from the gas exchange portion (30) is provided in the second concave wall portion (88). The inner opening portion (92) of the sampling port (90a) faces the second outlet side end surface (31b) of the gas exchange portion (30).

Description

Technical Field

[0001] The present invention relates to an artificial lung. Background Art

[0002] For example, an artificial lung is disclosed in International Publication No. 2016 / 009780, which includes: a gas exchange unit having hollow fiber membranes for gas exchange with blood; and a housing for accommodating the gas exchange unit. The housing has: a housing main body; a first lid member provided at one end of the housing main body so as to cover the inlet-side end face where the gas inlet of the hollow fiber membranes in the gas exchange unit is located; and a second lid member provided at the other end of the housing main body so as to cover the outlet-side end face where the gas outlet of the hollow fiber membranes in the gas exchange unit is located. A gas introduction port for introducing gas into the housing is provided on the first lid member, and a gas outlet port for discharging the gas that has flowed through the gas exchange unit to the outside of the housing is provided on the second lid member. Summary of the Invention

[0003] In the artificial lung as described above, a sampling port for collecting the gas discharged from the gas exchange unit is sometimes provided on the second lid member in order to measure the gas concentration. However, a pressure adjustment hole for adjusting the pressure of the gas discharged from the gas exchange unit is formed through the second lid member. Therefore, there is a risk that air flowing into the housing through the pressure adjustment hole is mixed into the sampling port, resulting in a change in the concentration of the gas collected from the sampling port.

[0004] The present invention has been made in view of such problems, and an object thereof is to provide an artificial lung capable of efficiently introducing the gas discharged from the gas exchange unit into the sampling port while suppressing the mixing of air into the sampling port.

[0005] One embodiment of the present invention is an artificial lung comprising: a gas exchange section having a hollow fiber membrane for performing gas exchange with respect to blood; and a shell having a gas inlet port and a gas outflow port, the shell having: a shell body accommodating the gas exchange section; a first cover member provided at one end of the shell body in a manner covering an inlet-side end face where a gas inlet of the hollow fiber membrane in the gas exchange section is located; and a second cover member provided at the other end of the shell body in a manner covering an outlet-side end face where a gas outlet of the hollow fiber membrane in the gas exchange section is located. In the artificial lung, the second cover component comprises: a cover body, which is opposite to the outlet side end face of the gas exchange part; and a concave wall portion, which is recessed toward the gas exchange part side compared with the inner surface of the cover body relative to the cover body, and a pressure regulating hole for regulating the pressure of the gas derived from the gas exchange part is formed through the cover body, and a sampling port for collecting the gas derived from the gas exchange part is provided on the concave wall portion, and the inner opening portion of the sampling port on the gas exchange part side is opposite to the outlet side end face of the gas exchange part.

[0006] According to the present invention, a pressure regulating hole is formed on the cover body, and a sampling port is provided on a concave wall portion that is recessed toward the gas exchange portion side compared to the inner surface of the cover body. Thus, compared with a case where the sampling port is provided on the cover body, it is possible to suppress the air that flows into the housing from the pressure regulating hole from mixing into the sampling port. In addition, since the inner opening of the sampling port is opposite to the outlet side end face of the gas exchange portion, the gas derived from the outlet side end face of the gas exchange portion can be efficiently introduced into the sampling port. BRIEF DESCRIPTION OF THE DRAWINGS

[0007] Figure 1 This is an explanatory block diagram showing the flow of gas supplied to the artificial lung according to one embodiment of the present invention.

[0008] Figure 2 yes Figure 1 Longitudinal section view of an artificial lung.

[0009] Figure 3 Viewed from the second cover member side Figure 2 Side view of an artificial lung.

[0010] Figure 4 It is along Figure 3 A cross-sectional view taken along line IV-IV.

[0011] Figure 5 It is along Figure 3 A cross-sectional view of line VV.

[0012] Figure 6 yes Figure 2Working instruction diagram of the artificial lung. Detailed implementation mode

[0013] Hereinafter, preferred implementation modes will be listed and the artificial lung of the present invention will be described with reference to the accompanying drawings.

[0014] Figure 1 The artificial lung 10 shown is a medical device that temporarily performs the function of the lung during surgeries such as cardiac surgery in the human body. That is, the artificial lung 10 is a device used for blood temperature regulation and blood oxygen regulation during extracorporeal blood circulation. The artificial lung 10 of the present implementation mode supplies anesthetic to the blood during extracorporeal blood circulation.

[0015] In Figure 1 , a gas supply passage 12 for supplying gas (oxygen and anesthetic gas) to the artificial lung 10 and a gas discharge passage 14 for guiding the gas (carbon dioxide gas, residual oxygen or residual anesthetic gas) discharged from the artificial lung 10 are connected to the artificial lung 10. In the gas supply passage 12, an oxygen mixer 16, an oxygen flow meter 18, and an anesthetic vaporizer 20 are arranged in sequence from upstream to downstream.

[0016] The oxygen mixer 16 adjusts the oxygen concentration by mixing compressed air and compressed oxygen. The oxygen flow meter 18 measures the oxygen flow rate in the gas supplied from the oxygen mixer 16. The anesthetic vaporizer 20 mixes the anesthetic gas obtained by evaporating the anesthetic into the oxygen. In the artificial lung 10, carbon dioxide gas in the blood taken from the patient is removed, and oxygen and anesthetic gas are supplied to the blood.

[0017] A circulation flow path 22 for guiding a part of the anesthetic gas discharged from the artificial lung 10 to the anesthetic vaporizer 20 is connected to the gas discharge passage 14. An exhaust device 24 for discharging the remaining anesthetic gas to the outside (such as the outside of the operating room, etc.) is arranged on the downstream side of the gas discharge passage 14 compared to the connection part with the circulation flow path 22.

[0018] As Figure 2 shown, the artificial lung 10 includes a housing 26, a heat exchange part 28, and a gas exchange part 30. The housing 26 is made of a hard resin. The housing 26 has: a housing main body 32 that houses the heat exchange part 28 and the gas exchange part 30; a first cover member 34 provided at one end (the end in the direction of arrow X1) of the housing main body 32; and a second cover member 36 provided at the other end (the end in the direction of arrow X2) of the housing main body 32.

[0019] The housing main body 32 includes a core body 38 that constitutes the central part of the artificial lung 10, and an outer cylinder 40 provided on the outer peripheral side of the core body 38. An annular accommodation space S for accommodating the cylindrical heat exchange part 28 and the cylindrical gas exchange part 30 is formed between the core body 38 and the outer cylinder 40. The accommodation space S functions as a blood flow path 41.

[0020] The core body 38 includes a first core body part 38a that constitutes one end of the core body 38, and a second core body part 38b that constitutes a part including the other end of the core body 38. The first core body part 38a and the second core body part 38b are connected to each other by a plurality of connecting parts 42.

[0021] The first core body part 38a has a tubular blood inflow part 46 and an annular wall part 48 that extends radially outward from the blood inflow part 46. A blood inflow port 46a through which blood guided from a patient via a blood extraction flow path (not shown) flows is formed in the blood inflow part 46.

[0022] The second core body part 38b is configured as a bottomed cylinder and has a cylinder part 50 and a blocking part 52 provided at one end of the cylinder part 50. The blocking part 52 is arranged to face the wall part 48 with a gap therebetween. A blood introduction passage 54 for guiding the blood flowing in from the blood inflow port 46a into the accommodation space S is provided between the blocking part 52 and the wall part 48.

[0023] The outer cylinder 40 is a cylindrical member arranged with a gap on the radial outer side of the core body 38. A tubular blood outflow part 56 is provided on the outer cylinder 40. A blood outflow port 56a for allowing the blood in the accommodation space S to flow out to a blood transfusion flow path (not shown) is formed in the blood outflow part 56.

[0024] The first cover member 34 is fixed to one end of the housing main body 32 by an adhesive 58 so as to cover the heat exchange part 28 and the gas exchange part 30 from the direction of arrow X1. The first cover member 34 has a first cover main body 60 that faces the first inlet side end face 29a that is one end face of the heat exchange part 28 and the second inlet side end face 31a that is one end face of the gas exchange part 30. A first partition wall part 66 that divides the space inside the first cover member 34 into a first heat medium flow path 62a and a first gas flow path 64a is provided on the first cover main body 60. The first cover main body 60 is formed in an annular shape.

[0025] A tubular heat medium inflow part 68 is provided at a position on the first cover main body 60 that faces the first inlet side end face 29a of the heat exchange part 28. A heat medium inflow port 68a for allowing a heat medium (such as water) to flow into the first heat medium flow path 62a is formed in the heat medium inflow part 68. The heat medium inflow part 68 extends radially outward from the first cover main body 60.

[0026] A tubular gas inflow portion 70 is provided at a portion of the first lid body 60 that faces the second inlet side end face 31a of the gas exchange portion 30. The gas inflow portion 70 is formed with a gas inflow port 70a for allowing gas (oxygen and anesthetic gas) to flow into the first gas flow path 64a. The gas inflow port 70a communicates with the gas supply passage 12 (see Figure 1 ).

[0027] The first heat medium flow path 62a is a flow path for guiding the heat medium introduced from the heat medium inflow port 68a to the heat exchange portion 28, and is located radially inside compared to the first partition portion 66. The first gas flow path 64a is a flow path for guiding the gas introduced from the gas inflow port 70a to the gas exchange portion 30, and is located radially outside compared to the first partition portion 66.

[0028] The second lid member 36 is fixed to the other end portion of the housing main body 32 by an adhesive 72 so as to cover the heat exchange portion 28 and the gas exchange portion 30 from the direction of arrow X2. As Figure 3 shown, the second lid member 36 has a second lid body 74, a first concave wall portion 82, and a second concave wall portion 88.

[0029] In Figure 2 , the second lid body 74 faces the first outlet side end face 29b that is the other end face of the heat exchange portion 28 and the second outlet side end face 31b that is the other end face of the gas exchange portion 30. A second partition portion 76 that divides the space inside the second lid member 36 into a second heat medium flow path 62b and a second gas flow path 64b is provided on the second lid body 74.

[0030] In Figure 3 , the second lid body 74 is formed in a circular shape. A plurality of (three in the example of Figure 3 ) ventilation holes 78 are formed through the second lid body 74 on the inner side compared to the heat exchange portion 28. The ventilation holes 78 communicate the space inside the cylindrical portion 50 with the external space (air) (see Figure 5 ).

[0031] As Figure 2 shown, a tubular heat medium outflow portion 80 is provided at a portion of the second lid body 74 that faces the first outlet side end face 29b of the heat exchange portion 28. The heat medium outflow portion 80 is formed with a heat medium outflow port 80a for allowing the heat medium to flow out from the second heat medium flow path 62b to the outside of the housing 26. The heat medium outflow portion 80 extends radially outward of the second lid body 74.

[0032] As Figure 4 shown, the first concave wall portion 82 faces the second outlet side end face 31b of the gas exchange portion 30. The first concave wall portion 82 is located near the heat medium outflow portion 80 (seeFigure 3 )。The first concave wall portion 82 is recessed toward the gas exchange portion 30 side with respect to the second lid body 74 as compared to the inner surface 74a of the second lid body 74.

[0033] That is, a step difference is formed between the first concave wall portion 82 and the second lid body 74. The inner surface 82a of the first concave wall portion 82 is located on the gas exchange portion 30 side only by the amount of the step difference as compared to the inner surface 74a of the second lid body 74. The outer surface 82b of the first concave wall portion 82 is located on the gas exchange portion 30 side only by the amount of the step difference as compared to the outer surface 74b of the second lid body 74. The outer surface 82b of the first concave wall portion 82 is located on the gas exchange portion 30 side as compared to the inner surface 74a of the second lid body 74.

[0034] A tubular gas outflow portion 84 is provided on the first concave wall portion 82. The gas outflow portion 84 protrudes from the first concave wall portion 82 toward the opposite side (arrow X2 direction) of the gas exchange portion 30. Thus, as compared with the case where the gas outflow portion 84 is provided on the second lid body 74, the protruding length of the gas outflow portion 84 in the arrow X2 direction with respect to the second lid body 74 can be shortened. The gas outflow portion 84 is formed with a gas outflow port 84a for allowing the gas in the second gas flow path 64b to flow out to the outside of the housing 26. The gas outflow port 84a communicates with the gas discharge passage 14 (see Figure 1 ).

[0035] In Figure 3 and Figure 5 , at a portion of the second lid body 74 that faces the second outlet side end surface 31b of the gas exchange portion 30, a pressure adjustment hole 86 is formed therethrough for adjusting the pressure of the gas led out from the gas exchange portion 30. In other words, the pressure adjustment hole 86 functions as a pressure relief hole for suppressing an excessive increase in the pressure of the second gas flow path 64b. The pressure adjustment hole 86 is formed in the outer peripheral edge portion of the second lid body 74.

[0036] As Figure 3 shown, the pressure adjustment hole 86 is composed of a first hole 86a, a second hole 86b, and a third hole 86c. The first hole 86a is disposed adjacent to the first concave wall portion 82 in the circumferential direction (arrow R1 direction) of the second lid body 74. The second hole 86b is disposed adjacent to the first concave wall portion 82 in the opposite direction (arrow R2 direction) of the side where the first hole 86a is located. In other words, the first hole 86a and the second hole 86b are arranged to sandwich the first concave wall portion 82 from the circumferential direction of the second lid body 74. The second hole 86b is located between the first concave wall portion 82 and the heat medium outflow portion 80.

[0037] The third hole 86c is disposed adjacent to the heat medium outlet portion 80 on the side opposite to the side where the second hole 86b is located (in the direction of arrow R2). That is, the second hole 86b and the third hole 86c are arranged to sandwich the heat medium outlet portion 80 in the circumferential direction of the second lid body 74.

[0038] The first hole 86a, the second hole 86b, and the third hole 86c are each formed in a quadrilateral shape. The third hole 86c extends longer in the circumferential direction of the second lid body 74 than the first hole 86a and the second hole 86b. However, the shapes and sizes of the first hole 86a, the second hole 86b, and the third hole 86c can be appropriately changed.

[0039] The second concave wall portion 88 is disposed away from the first hole 86a in the direction opposite to the side where the first concave wall portion 82 is located (in the direction of arrow R1). In Figure 5 this case, the second concave wall portion 88 is recessed toward the gas exchange portion 30 side with respect to the second lid body 74 as compared with the inner surface 74a of the second lid body 74.

[0040] That is, a step difference is formed between the second concave wall portion 88 and the second lid body 74. The inner surface 88a of the second concave wall portion 88 is located on the gas exchange portion 30 side only by the amount of the step difference as compared with the inner surface 74a of the second lid body 74. The outer surface 88b of the second concave wall portion 88 is located on the gas exchange portion 30 side only by the amount of the step difference as compared with the outer surface 74b of the second lid body 74. The outer surface 88b of the second concave wall portion 88 is located on the gas exchange portion 30 side as compared with the inner surface 74a of the second lid body 74.

[0041] A tubular port forming portion 90 is provided on the second concave wall portion 88. The port forming portion 90 projects from the second concave wall portion 88 toward the side opposite to the gas exchange portion 30 (in the direction of arrow X2). The port forming portion 90 is formed with a sampling port 90a for collecting the gas led out from the gas exchange portion 30. The gas collected from the sampling port 90a is used for measuring the gas concentration (oxygen concentration or anesthetic gas concentration).

[0042] In Figure 3 this case, the sampling port 90a is separated by a predetermined angle θ or more in the circumferential direction of the second lid body 74 with respect to the pressure regulating hole 86 (the first hole 86a). The predetermined angle θ is set to, for example, 60°. However, the predetermined angle θ can be appropriately changed.

[0043] As Figure 5 shown, the inner opening 92 on the gas exchange portion 30 side (in the direction of arrow X1) in the sampling port 90a faces the second outlet side end face 31b of the gas exchange portion 30. The first distance L1 between the inner opening 92 and the second outlet side end face 31b is smaller than the second distance L2 between the second outlet side end face 31b and the inner surface 74a of the second lid body 74 (refer toFigure 2 ) is short. The first distance L1 is set, for example, to be 1 mm or more and 5 mm or less, and the second distance L2 is preferably set to be about 7 mm. However, the first distance L1 and the second distance L2 can be set appropriately.

[0044] In Figure 2 , the heat exchange section 28 is formed of a plurality of first hollow fiber membranes 28a into a cylindrical shape. Each first hollow fiber membrane 28a is wound around the outer surface of the core 38 so as to extend over the entire length of the heat exchange section 28. A gap through which blood can flow is formed between adjacent first hollow fiber membranes 28a. The opening (heat medium inlet) on one end side of each first hollow fiber membrane 28a is located on the first inlet side end face 29a of the heat exchange section 28 so as to communicate with the inside of the first heat medium flow path 62a. The opening (heat medium outlet) on the other end side of each first hollow fiber membrane 28a is located on the first outlet side end face 29b of the heat exchange section 28 so as to communicate with the inside of the second heat medium flow path 62b. That is, the heat medium flows through the inner cavity of each first hollow fiber membrane 28a.

[0045] The first hollow fiber membrane 28a is formed so as not to allow the heat medium and blood to permeate. As the material constituting the first hollow fiber membrane 28a, for example, polymer materials such as polypropylene, polyamide, polyethylene, polysulfone, polyacrylonitrile, polytetrafluoroethylene, and polymethylpentene can be used, and polyamide is preferred. The inner diameter of the first hollow fiber membrane 28a is preferably set in the range of 50 μm to 700 μm. In this case, the flow path resistance of the heat medium flowing through the inner cavity of the first hollow fiber membrane 28a can be relatively reduced. The outer diameter of the first hollow fiber membrane 28a is preferably set in the range of 100 μm to 1000 μm, and more preferably set in the range of 120 μm to 800 μm. In this case, the surface area of the first hollow fiber membrane 28a can be increased efficiently.

[0046] The gas exchange section 30 is configured to supply oxygen and anesthetic gas to the blood flowing in the blood flow path 41 and remove carbon dioxide gas from the blood. The gas exchange section 30 is disposed on the outer peripheral side of the heat exchange section 28. That is to say, the gas exchange section 30 and the heat exchange section 28 are arranged to overlap each other in the radial direction. The entire length of the gas exchange section 30 is the same as the entire length of the heat exchange section 28.

[0047] The gas exchange section 30 is formed in a cylindrical shape by a plurality of second hollow fiber membranes 30a. Each second hollow fiber membrane 30a is wound around the outer surface of the heat exchange section 28 so as to extend over the entire length of the gas exchange section 30. A gap through which blood can flow is formed between adjacent second hollow fiber membranes 30a. The opening (gas inlet) on one end side of each second hollow fiber membrane 30a is located on the second inlet side end face 31a of the gas exchange section 30 so as to communicate with the inside of the first gas flow path 64a. The opening (gas outlet) on the other end side of each second hollow fiber membrane 30a is located on the second outlet side end face 31b of the gas exchange section 30 so as to communicate with the inside of the second gas flow path 64b. That is, gas (oxygen, anesthetic gas, or carbon dioxide gas) flows through the lumen of each second hollow fiber membrane 30a.

[0048] The second hollow fiber membrane 30a is configured to allow oxygen, anesthetic gas, or carbon dioxide gas to pass through but not allow blood to pass through. The constituent material and inner diameter of the second hollow fiber membrane 30a can be set to be the same as those of the first hollow fiber membrane 28a.

[0049] Next, the operation of the artificial lung 10 configured as described above will be described.

[0050] As Figure 6 shown, the heat medium is supplied to the heat medium inlet port 68a of the artificial lung 10. The heat medium supplied to the heat medium inlet port 68a is introduced into the lumen of each first hollow fiber membrane 28a from the first inlet side end face 29a of the heat exchange section 28 via the first heat medium flow path 62a.

[0051] As Figure 1 shown, oxygen is supplied from the oxygen mixer 16 to the anesthesia vaporizer 20 via the gas supply passage 12. In the anesthesia vaporizer 20, anesthetic gas is mixed into the oxygen. Then, as Figure 6 shown, oxygen and anesthetic gas are supplied to the gas inlet port 70a of the artificial lung 10. The oxygen and anesthetic gas supplied to the gas inlet port 70a are introduced into the lumen of each second hollow fiber membrane 30a from the second inlet side end face 31a of the gas exchange section 30 via the first gas flow path 64a.

[0052] Blood guided from the patient via the blood extraction flow path is supplied to the blood inlet port 46a of the artificial lung 10 by the action of a centrifugal pump (not shown). The blood supplied to the blood inlet port 46a is guided to the blood flow path 41 (accommodation space S) via the blood introduction passage 54. The blood guided to the blood flow path 41 flows in the accommodation space S toward the radially outer side in the gap between adjacent first hollow fiber membranes 28a of the heat exchange section 28. Thereby, heat exchange can be performed between the heat medium flowing in the lumen of the first hollow fiber membrane 28a and the blood flowing outside the first hollow fiber membrane 28a.

[0053] The blood that has undergone heat exchange flows radially outward within the accommodation space S through the gaps between adjacent second hollow fiber membranes 30a of the gas exchange unit 30. As a result, oxygen and anesthetic gas flowing within the lumen of the second hollow fiber membrane 30a permeate through the wall portion of the second hollow fiber membrane 30a and are supplied to the blood, and carbon dioxide gas in the blood permeates through the wall portion of the second hollow fiber membrane 30a and is discharged to the outside of the second hollow fiber membrane 30a. That is, oxygen and anesthetic gas dissolve in the blood. The blood after gas exchange is guided from the blood outflow port 56a to the blood transfusion path and returned to the patient.

[0054] The heat medium flowing through the heat exchange unit 28 is led out from the first outlet side end surface 29b of the heat exchange unit 28 to the second heat medium flow path 62b and flows out to the outside of the artificial lung 10 through the heat medium outflow port 80a. The gas (residual oxygen, residual anesthetic gas, or carbon dioxide gas) flowing through the gas exchange unit 30 is led out from the second outlet side end surface 31b of the gas exchange unit 30 to the second gas flow path 64b and is discharged to the gas discharge path 14 through the gas outflow port 84a (refer to Figure 1 ). A part of the residual anesthetic gas guided to the gas discharge path 14 is guided to the anesthetic vaporizer 20 through the circulation flow path 22 and reused. On the other hand, the anesthetic gas guided to the exhaust device 24 is discharged to the outside of the operating room.

[0055] The artificial lung 10 of the present embodiment exhibits the following effects.

[0056] In the artificial lung 10, the second lid member 36 has a second lid main body 74 facing the second outlet side end surface 31b of the gas exchange unit 30, and a second concave wall portion 88 that is recessed toward the gas exchange unit 30 side relative to the inner surface 74a of the second lid main body 74 with respect to the second lid main body 74. A pressure adjustment hole 86 for adjusting the pressure of the gas led out from the gas exchange unit 30 is formed in the second lid main body 74. A sampling port 90a for collecting the gas led out from the gas exchange unit 30 is provided on the second concave wall portion 88, and the inner opening portion 92 on the gas exchange unit 30 side of the sampling port 90a faces the second outlet side end surface 31b of the gas exchange unit 30.

[0057] According to this structure, the pressure regulating hole 86 is formed in the second cover body 74, and the sampling port 90a is provided in the second concave wall portion 88 that is recessed toward the gas exchange unit 30 side relative to the second cover body 74. Therefore, compared with the case where the sampling port 90a is provided in the second cover body 74, it is possible to suppress the air that flows into the housing 26 from the pressure regulating hole 86 from mixing into the sampling port 90a. In addition, since the inner opening portion 92 of the sampling port 90a is opposite to the second outlet side end surface 31b of the gas exchange unit 30, the gas discharged from the second outlet side end surface 31b of the gas exchange unit 30 can be efficiently introduced into the sampling port 90a.

[0058] The second cover body 74 is formed in a circular shape, and the sampling port 90 a is separated from the pressure adjustment hole 86 by more than 60° in the circumferential direction of the second cover body 74 .

[0059] According to such a configuration, it is possible to further suppress the air flowing in from the pressure regulating hole 86 from mixing into the sampling port 90 a .

[0060] The pressure regulating hole 86 is located near the gas outflow port 84a.

[0061] According to such a configuration, the air flowing into the second gas flow path 64 b from the pressure regulating hole 86 can be efficiently discharged to the outside from the gas outflow port 84 a .

[0062] The pressure adjustment hole 86 is composed of a plurality of holes (a first hole 86 a , a second hole 86 b , and a third hole 86 c ).

[0063] According to such a configuration, the pressure of the gas output from the gas exchange unit 30 can be effectively adjusted.

[0064] A first distance L1 between the inner opening 92 of the sampling port 90 a and the second outlet-side end surface 31 b of the gas exchange unit 30 is set to be not less than 1 mm and not more than 5 mm.

[0065] According to such a configuration, the exhaust gas led out from the gas exchange unit 30 can be efficiently guided to the sampling port 90 a .

[0066] The present invention is not limited to the above-described embodiment, and various modifications can be made without departing from the gist of the present invention.

[0067] The above embodiments can be summarized as follows.

[0068] The above embodiment discloses an artificial lung (10), comprising: a gas exchange section (30) having a hollow fiber membrane (30a) for performing gas exchange with respect to blood; and a housing (26) having a gas inlet port (70a) and a gas outflow port (84a), wherein the housing comprises: a housing body (32) accommodating the gas exchange section; a first cover member (34) provided at one end of the housing body in such a manner as to cover an inlet side end face (31a) where a gas inlet of the hollow fiber membrane in the gas exchange section is located; and a second cover member (36) provided at an outlet side end face (31b) where a gas outlet of the hollow fiber membrane in the gas exchange section is located. Located at the other end of the shell body, in the artificial lung, the second cover component comprises: a cover body (74), which is opposite to the outlet side end face of the gas exchange part; and a concave wall portion (88), which is recessed toward the gas exchange part side relative to the cover body and the inner surface (74a) of the cover body, and a pressure regulating hole (86) for regulating the pressure of the gas discharged from the gas exchange part is formed through the cover body, and a sampling port (90a) for collecting the gas discharged from the gas exchange part is provided on the concave wall portion, and the inner opening portion (92) on the gas exchange part side of the sampling port is opposite to the outlet side end face of the gas exchange part.

[0069] In the above-mentioned artificial lung, the cover body may be formed in a circular shape, and the sampling port may be separated from the pressure regulating hole by 60° or more in the circumferential direction of the cover body.

[0070] In the above-mentioned artificial lung, the pressure regulating hole may be located near the gas outflow port.

[0071] In the above-mentioned artificial lung, the pressure regulating hole may be composed of a plurality of holes (86a to 86c).

[0072] In the above-mentioned artificial lung, a distance (L1) between the inner opening of the sampling port and the outlet-side end surface of the gas exchange portion may be set to be not less than 1 mm and not more than 5 mm.

Claims

1. An artificial lung, comprising: a gas exchange unit having a hollow fiber membrane for gas exchange with blood; and a housing provided with a gas inlet port and a gas outlet port, wherein the housing has: a housing main body that houses the gas exchange unit; a first lid member provided at one end of the housing main body so as to cover the inlet-side end face where the gas inlet of the hollow fiber membrane in the gas exchange unit is located; and a second lid member provided at the other end of the housing main body so as to cover the outlet-side end face where the gas outlet of the hollow fiber membrane in the gas exchange unit is located, and the artificial lung is characterized in that the second lid member has: a lid main body that faces the outlet-side end face of the gas exchange unit; and a concave wall portion that is recessed toward the gas exchange unit side relative to the lid main body and the inner surface of the lid main body, a pressure adjustment hole is formed through the lid main body for adjusting the pressure of the gas led out from the gas exchange unit, a sampling port for collecting the gas led out from the gas exchange unit is provided on the concave wall portion, and the inner opening portion on the gas exchange unit side in the sampling port faces the outlet-side end face of the gas exchange unit.

2. The artificial lung according to claim 1, characterized in that the lid main body is formed in a circular shape, and the sampling port is separated by 60° or more in the circumferential direction of the lid main body with respect to the pressure adjustment hole.

3. The artificial lung according to claim 1 or 2, characterized in that the pressure adjustment hole is located near the gas outlet port.

4. The artificial lung according to any one of claims 1 to 3, characterized in that the pressure adjustment hole is composed of a plurality of holes.

5. The artificial lung according to any one of claims 1 to 4, characterized in that the distance between the inner opening portion of the sampling port and the outlet-side end face of the gas exchange unit is set to be 1 mm or more and 5 mm or less.

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