Stent graft

Abstract

The present invention provides a stent graft comprising a stent graft body and a drug storage device; the stent graft body has a circulation space connected at both ends; the drug storage device is fixed to the stent graft body and at least partially located outside the stent graft body; the drug storage device has a drug storage space within it, and a drug delivery hole is provided in the drug storage device, which connects the drug storage space to the external environment. Compared with the prior art, the stent graft provided by the present invention can store antibacterial and anti-infective drugs in the drug storage device and release the drugs outward through the drug delivery hole, thereby giving the stent graft better anti-infection capabilities.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a stent graft. Background Art

[0002] A covered stent is a metal stent coated with a special membrane material (such as polytetrafluoroethylene, Dacron, polyester, or polyurethane). This stent retains the functionality of a metal stent while also possessing the properties of the membrane material. Typically made of a nickel-titanium alloy, a covered stent is coated with a polymer membrane to form a self-expanding artificial conduit that is fixed within the body's blood vessels. It is used to treat conditions such as aneurysms, arterial dissections, and vascular ruptures.

[0003] Thoracic endovascular aortic stent graft repair (TEVAR) and abdominal endovascular aortic stent graft repair (EVAR) are minimally invasive procedures within the vascular lumen. Compared to traditional surgical methods, TEVAR and EVAR offer significant advantages such as less trauma, shorter recovery time, and fewer complications.

[0004] Due to the high incidence of infection with stent-grafts, conditions such as infected aortic aneurysms, aortic trauma with mediastinal infection, and aortic damage from esophageal foreign bodies remain relative contraindications for endovascular treatment with stent-grafts. Furthermore, with the widespread use of TEVAR procedures, the number of patients with long-term stent-graft infections is increasing. Currently, these infections can only be treated with systemic antibiotics, which are surgically invasive and have a very high mortality rate. Summary of the Invention

[0005] Aiming at the technical problems in the prior art that stent grafts are prone to infection and have low anti-infection ability, the present invention provides a stent graft that can effectively improve the anti-infection ability.

[0006] A stent graft comprises a stent graft body and a drug storage device;

[0007] The stent graft body has a flow space with two ends connected;

[0008] The drug storage device is fixed on the coated stent body, and at least partially located on the outside of the coated stent body. The drug storage device has a drug storage space inside, and a drug delivery hole is opened on the drug storage device, which connects the drug storage space with the external environment.

[0009] Preferably, the drug storage device is embedded in the coating of the coated stent body.

[0010] Preferably, the drug storage device includes an axial drug storage tube and a circumferential drug storage tube;

[0011] The axial drug storage tube is arranged along the axial direction of the stent graft body;

[0012] The circumferential drug storage tube is connected to the axial drug storage tube, and the circumferential drug storage tube is arranged along the circumference of the stent graft body;

[0013] The drug storage space includes a first drug storage space and a second drug storage space, wherein the first drug storage space is opened in the axial drug storage tube, and the second drug storage space is opened in the circumferential drug storage tube, and the second drug storage space is connected to the first drug storage space;

[0014] The drug administration holes are both provided on the axial drug storage tube and the circumferential drug storage tube.

[0015] Preferably, a plurality of the axial drug storage tubes are provided, and the plurality of the axial drug storage tubes are distributed in sequence along the circumference of the stent graft body, and two adjacent axial drug storage tubes are spaced apart from each other.

[0016] Preferably, a plurality of the circumferential drug storage tubes are provided, and the plurality of the circumferential drug storage tubes are distributed in sequence along the axial direction of the stent graft body, and two adjacent circumferential drug storage tubes are spaced apart from each other.

[0017] Preferably, it also includes a docking device;

[0018] The docking device is fixed on the stent graft body, and a drug replenishing channel is provided on the docking device, and the drug replenishing channel is communicated with the drug storage space.

[0019] Preferably, the docking device includes a mounting portion and a docking portion:

[0020] The mounting portion is fixedly connected to the stent graft body and is located at one end of the stent graft body along the axial direction of the stent graft body;

[0021] The docking portion is fixed on the mounting portion;

[0022] The medicine replenishing channel is provided in the mounting portion.

[0023] Preferably, the mounting portion includes an outer sleeve, an interface tube and a hemostatic valve;

[0024] The drug-replenishing channel is surrounded by the interface tube, a portion of the interface tube is disposed in the outer sleeve, another portion of the interface tube extends out of the outer sleeve and is connected to the stent graft body, and the portion of the interface tube located in the outer sleeve is disposed through the outer sleeve;

[0025] The hemostatic valve is arranged in the interface tube;

[0026] The docking portion is fixed on the outer sleeve.

[0027] Preferably, the interface pipe includes an inner pipe, an inner layer interface pipe, an outer layer interface pipe, a first connecting pipe and a second connecting pipe;

[0028] The inner tube is located in the outer tube;

[0029] The inner layer interface tube is in close contact with the inner surface of the stent graft body;

[0030] The outer interface tube is in contact with the outer surface of the stent graft body, and is connected to the drug storage device;

[0031] The first connecting pipe connects the inner layer interface pipe and the inner pipe;

[0032] The second connecting pipe connects the outer interface pipe and the inner pipe;

[0033] The medicine-replenishing channel is surrounded by the inner tube, the second connecting tube and the outer interface tube.

[0034] Preferably, the docking portion is a magnetic docking portion.

[0035] Compared with the prior art, the stent graft provided by the present invention includes a stent graft body and a drug storage device; the stent graft body has a circulation space connected at both ends; the drug storage device is fixed to the stent graft body, and at least part of the drug storage device is located outside the stent graft body, the drug storage device has a drug storage space inside, and a drug administration hole is provided on the drug storage device, and the drug administration hole connects the drug storage space with the external environment. Antibacterial and anti-infective drugs can be stored in the stent graft through the drug storage device, and the antibacterial and anti-infective drugs stored in the drug storage device can be released outward through the drug administration hole, thereby effectively improving the anti-infection ability of the stent graft after being installed in the human body, and also making the stent graft have more possibilities for use. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without any creative work.

[0037] Figure 1 A front view of a stent graft provided in one embodiment;

[0038] Figure 2 for Figure 1 A schematic diagram of the cross-sectional structure of the stent graft at one angle is shown;

[0039] Figure 3 for Figure 1 A schematic diagram of the cross-sectional structure of the docking device and the stent graft body at another angle;

[0040] Figure 4 for Figure 1 Schematic diagram of the three-dimensional structure of the docking device shown. DETAILED DESCRIPTION

[0041] In order to help those skilled in the art better understand the technical solutions in this application, the technical solutions in the embodiments of this application will be clearly and completely described below. Obviously, the embodiments described are only part of the embodiments of this application, not all of the embodiments. Based on the embodiments in this application, all other embodiments obtained by those skilled in the art without making any creative efforts shall fall within the scope of protection of this application.

[0042] It should be noted that when an element is referred to as being “fixed on,” “installed on,” or “set on” another element, it can be directly on the other element or indirectly set on the other element; when an element is referred to as being “connected to” another element, it can be directly connected to the other element or indirectly connected to the other element.

[0043] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification for people familiar with this technology to understand and read, and are not used to limit the conditions under which this application can be implemented. Therefore, they have no substantive technical significance. Any structural modification, change in proportional relationship or adjustment of size should still fall within the scope of the technical content disclosed in this application without affecting the efficacy and purpose that can be achieved by this application.

[0044] The present invention provides a stent graft comprising a stent graft body and a drug storage device. The stent graft body has a circulation space connected at both ends. The drug storage device is fixed to the stent graft body and at least partially located outside the stent graft body. The drug storage device has a drug storage space within it and is provided with a drug delivery hole, which connects the drug storage space to the external environment. The drug storage device can store antibacterial and anti-infective drugs and can release them outward through the drug delivery hole, thereby enhancing the stent graft's anti-infection capabilities.

[0045] Please refer to Figures 1 to 4. This embodiment provides a covered stent 100. Specifically, the covered stent 100 is an ascending aorta covered stent in this embodiment. The covered stent 100 includes a covered stent body 10 and a drug storage device 20. The covered stent body 10 has a circulation space 11 connected at both ends, so that when the covered stent 100 is installed in the human body, blood can circulate well through the circulation space 11. The drug storage device 20 is fixed on the covered stent body 10, and the drug storage device 20 is at least partially located on the outside of the covered stent body 10, that is, the drug storage device 20 is at least partially located on the side of the outer surface of the covered stent body 10, so that the drug can be conveniently administered to the inner wall of the blood vessel through the part of the drug storage device 20 located on the outside of the covered stent body 10. Specifically, in this embodiment, the drug storage device 20 is arranged as a whole on the outside of the covered stent body 10. The drug storage device 20 has a drug storage space inside, that is, the drug storage device 20 is a hollow structure, and the drug storage device 20 can accommodate and store drugs. The drug storage device 20 is provided with a drug delivery hole 21, and the drug delivery hole 21 connects the drug storage space with the external environment. Therefore, when the coated stent 100 is installed in the human body, the drug stored in the drug storage space can be released outward through the drug delivery hole 21, thereby better avoiding infection after the coated stent 100 is installed in the human body. Specifically, the coated stent body 10 is composed of a metal stent and a special coating material combined together to form a tubular structure, that is, the coated stent body 10 is composed of a metal stent 12 and a coating 13. In this embodiment, the metal stent 12 is made of nickel-titanium alloy, and the coating 13 is made of EPTFE (expanded polytetrafluoroethylene) film.

[0046] Understandably, due to the high infection rate of stent grafts, aortic stent grafts are still contraindicated in the treatment of infected aneurysms, aortic trauma with severe pulmonary or mediastinal infection, and aortic damage from foreign bodies in the esophagus. This deprives many patients of the opportunity for minimally invasive surgery, while those who cannot tolerate invasive surgery under cardiopulmonary bypass are likely to die. Furthermore, with the increasing clinical application of TEVAR (thoracic endovascular aortic stent graft repair), the incidence of late-stage stent infections is increasing. The treatment of these late-stage stent infections is also quite challenging, and the patient mortality rate is very high.

[0047] The stent graft 100 provided in this embodiment is provided with the drug storage device 20, and the drug storage device 20 is provided with a drug delivery hole 21, so that antibacterial and anti-infective drugs can be stored in the drug storage device 20. After the stent graft 100 is installed in the human body, the stored antibacterial and anti-infective drugs can be gradually released through the drug delivery hole 21, thereby effectively improving the anti-infection ability of the stent graft 100 and making the stent graft 100 have more application possibilities.

[0048] Preferably, the drug storage device 20 is embedded in the coating 13, thereby better ensuring the connection stability between the drug storage device 20 and the coated stent body 10, and also better ensuring the anti-seepage performance of the coated stent body 10. In addition, there is no need to install the drug storage device 20 in the metal stent 12, which also makes the manufacturing process more simple.

[0049] Preferably, the drug storage device 20 includes an axial drug storage tube 22 and a circumferential drug storage tube 23. The axial drug storage tube 22 is arranged along the axial direction of the stent graft body 10. The circumferential drug storage tube 23 is connected to the axial drug storage tube 22 and is arranged along the circumference of the stent graft body 10. The drug storage space includes a first drug storage space and a second drug storage space. The first drug storage space is opened in the axial drug storage tube 22, and the second drug storage space is opened in the circumferential drug storage tube 23, and the second drug storage space is connected to the first drug storage space. That is, the axial drug storage tube 22 and the circumferential drug storage tube 23 are both hollow structures. Both the axial drug storage tube 22 and the circumferential drug storage tube 23 can store drugs, and the drugs can flow between the axial drug storage tube 22 and the circumferential drug storage tube 23. The drug administration holes 21 are both provided on the axial drug storage tube 22 and the circumferential drug storage tube 23, that is, the axial drug storage tube 22 and the circumferential drug storage tube 23 can release drugs outward. Thus, the drugs can be better released to the outside through the axial drug storage tube 22 and the circumferential drug storage tube 23, and the anti-infection ability of the stent graft 100 is better guaranteed. More preferably, the axial drug storage tube 22 and the circumferential drug storage tube 23 are both provided with a plurality of drug administration holes 21, and the plurality of drug administration holes 21 are evenly distributed on the axial drug storage tube 22 and the circumferential drug storage tube 23. Thus, when the drug is released, the release in each area is more uniform. Specifically, in the present embodiment, the circumferential drug storage tube 23 is in the shape of an arc. Of course, in other embodiments, the circumferential drug storage tube 23 may also be in the shape of a ring, which can be selected according to the size of the actual required drug administration area.

[0050] Preferably, a plurality of axial drug storage tubes 22 are provided, and the plurality of axial drug storage tubes 22 are sequentially distributed along the circumference of the stent graft body 10, and adjacent two axial drug storage tubes 22 are spaced apart from each other, thereby making the drug delivery of the stent graft 100 more uniform. In this embodiment, three axial drug storage tubes 22 are used as an example for description.

[0051] Preferably, a plurality of circumferential drug storage tubes 23 are provided, and the plurality of circumferential drug storage tubes 23 are sequentially distributed along the axial direction of the stent graft body 10, and adjacent circumferential drug storage tubes 23 are spaced apart from each other, thereby further ensuring more uniform drug delivery to the stent graft 100. In this embodiment, five circumferential drug storage tubes 23 are used as an example for description.

[0052] Preferably, the drug storage device 20 is a 2.6-3F microcatheter.

[0053] Preferably, the stent graft 100 further includes a docking device 30, the docking device 30 is fixed on the stent graft body 10, and a drug replenishing channel 40 is provided on the docking device 30, and the drug replenishing channel 40 is connected to the drug storage space. Thus, the docking device 30 can facilitate the docking between the stent graft 100 and other medical devices. When the stent graft 100 is installed in the human body and a second intervention operation is performed, the docking efficiency between other medical devices and the stent graft 100 can be effectively improved, the difficulty of the operation can be reduced, and the operation time can be shortened. In addition, the docking device 30 can also realize long-term drug supplementation in the drug storage device 20, so as to better ensure the long-term anti-infection ability of the stent graft 100.

[0054] Preferably, the docking device 30 includes a mounting portion 31 and a docking portion 32. The mounting portion 31 is fixedly connected to the stent graft body 10 and is located at one end of the stent graft body 10 along the axial direction of the stent graft body 10, thereby further facilitating docking with other medical devices. The docking portion 32 is fixed to the mounting portion 31, and the drug supplement channel 40 is disposed in the mounting portion 31.

[0055] Preferably, the mounting portion 31 includes an outer sleeve 311, a mouthpiece 312, and a hemostatic valve 313. The drug-replenishing passage 40 is enclosed by the mouthpiece 312, i.e., the mouthpiece 312 is hollow. A portion of the mouthpiece 312 is disposed within the outer sleeve 311, while another portion extends beyond the outer sleeve 311 and connects to the stent graft body 10. The portion of the mouthpiece 312 located within the outer sleeve 311 extends through the outer sleeve 311. Thus, the hollow mouthpiece 312 allows for efficient guidance of catheters and guidewires into the area where the stent graft body 10 is located. Long-term, multiple drug administration can also be delivered to the area where the stent graft body 10 is located through the hollow mouthpiece 312. The hemostatic valve 313 is disposed within the mouthpiece 312, and the docking portion 32 is fixed to the outer sleeve 311. Therefore, the hemostatic valve 313 can prevent the high-pressure blood flow in the blood vessel from entering the effective action area of ​​the coated stent body 10 through the interface tube 312 and causing bleeding.

[0056] Preferably, the interface tube 312 includes an inner tube 3121, an inner interface tube 3122, an outer interface tube 3123, a first connecting tube 3124, and a second connecting tube 3125. The inner tube 3121 is located within the outer tube 311. The inner interface tube 3122 is in close contact with the inner surface 14 of the stent graft body 10, the outer interface tube 3123 is in close contact with the outer surface 15 of the stent graft body 10, and the outer interface tube 3123 is connected to the drug storage device 20. The first connecting tube 3124 connects the inner interface tube 3122 and the inner tube 3121, and the second connecting tube 3125 connects the outer interface tube 3123 and the inner tube 3121. The drug replenishing channel 40 is surrounded by the inner tube 3121, the second connecting tube 3125, and the outer interface tube 3123. That is, the interface tube 312 is divided into two parts near the end of the coated stent body 10, and is respectively fixed to the inner and outer surfaces of the coated stent body 10, thereby better ensuring the connection stability between the docking device 30 and the coated stent body 10. And through the inner layer interface tube 3122 and the outer layer interface tube 3123, during the operation, the catheter and guide wire can be introduced into the inside or outside of the coated stent body 10 according to actual needs. Or, drugs can be delivered into the inside or outside of the coated stent body 10 according to actual needs. In this embodiment, the interface tube 312 is a Y-shaped tube, that is, the inner layer interface tube 3122, the first connecting tube 3124 and the outer layer interface tube 3123, the second connecting tube 3125 are symmetrically arranged.

[0057] Preferably, the central axis of the inner tube 3121 coincides with the central axis of the outer tube 311, that is, the inner tube 3121 is disposed at the exact center of the outer tube 311. The docking portion 32 is offset from the inner tube 3121, so that the docking portion 32 does not block the inner tube 3121, does not affect the insertion of a catheter or guidewire into the inner tube 3121, or does not affect the delivery of drugs to the inner tube 3121.

[0058] Preferably, the outer sleeve 311 is a soft silicone outer sleeve, and the interface tube 312 is a soft silicone interface tube, thereby better ensuring safety and further avoiding damage to the human body.

[0059] Preferably, the docking portion 32 is a magnetic docking portion. That is, the docking portion 32 is made of magnetic material, so that it can dock with medical devices with magnetic structures (such as catheters and guidewires with magnetic structures), and complete the docking between other medical devices and the coated stent 100 by magnetic attraction. Of course, in other embodiments, the docking method between the docking portion 32 and other medical devices can also adopt a structural shape method, such as a groove or a protrusion can be provided on the docking portion 32, and other medical devices are correspondingly provided with a protrusion matching the groove or a groove matching the protrusion, so as to achieve the docking between the docking portion 32 and other medical devices. In this embodiment, the docking portion 32 is made of magnetic material, so that the docking between the coated stent 100 and other medical devices is completed by magnetic attraction, which can effectively improve the docking efficiency, reduce the difficulty of docking, make alignment easier, and better reduce the difficulty of surgery and surgery time.

[0060] Preferably, the docking portion 32 is in an arc shape, thereby better facilitating the docking between the docking portion 32 and other medical devices. Specifically, in this embodiment, the docking portion 32 is semicircular. More preferably, the opening direction of the docking portion 32 is toward the center direction of the stent graft body 10, that is, the docking portion 32 is located on the side away from the center direction of the stent graft body 10, so that the docking portion 32 does not block the normal circulation of blood inside the stent graft body 10.

[0061] Preferably, the docking device 30 is fixedly connected to the metal bracket 12 of the stent graft body 10, thereby further ensuring the connection and fixing effect between the docking device 30 and the stent graft body 10, and better ensuring the connection stability. Specifically, in this embodiment, the outer sleeve 311 is fixedly connected to the metal bracket 12 at the end of the stent graft body 10.

[0062] Preferably, the docking device 30 is provided with a heparin coating, and the docking device 30 is subjected to an anti-cell adhesion treatment, so as to prevent thrombosis and endothelial ingrowth as long as possible.

[0063] Preferably, the stent graft 100 is coated with a silver nitrate drug coating to enhance the bactericidal effect of the stent graft 100 during initial implantation. It is understood that existing drug coating technologies are used for anti-proliferative drugs to prevent intimal hyperplasia in the stent. In this embodiment, the use of silver nitrate, a bactericidal drug, as a coating on the stent graft 100 is safer and more effective, better ensuring anti-infection capabilities.

[0064] In this embodiment, two docking devices 30 are provided at the end of the stent graft body 10. Of course, in other embodiments, the number of docking devices 30 may be greater depending on actual needs, and multiple docking devices 30 may be distributed in a circular array at one end of the stent graft body 10. In some embodiments, the docking devices 30 may be provided at both ends of the stent graft body 10, and the choice may be made based on actual needs.

[0065] The stent graft 100 provided in this embodiment is provided with the drug storage device 20 and the docking device 30. The drug storage device 20 and the reserved docking device 30 can be used to re-infuse the antibacterial drug when an infection occurs in the long term. The drug filling interface is a long-term interface dedicated to the intraluminal stent (i.e., the docking device 30). The drug storage device 20 forms a network in the inner and outer layers of the stent graft body 10, which can fully provide an antibacterial drug spray can around the stent. This makes it possible to easily complete the drug filling treatment of sensitive antibiotics after docking with the docking device 30 through the catheter guide wire (magnetic), greatly improving the anti-infection ability of the stent graft 100. It also solves the problem that it is difficult to effectively fight infection in deep anatomical areas around the stent graft 100 (such as the mediastinum). At the same time, it also conveniently solves the problem of needing to use different antibiotics for different bacterial infections. Sensitive antibiotics can be infused according to the culture results to quickly complete deep drug administration.

[0066] The docking device 30 can be used as a docking inspection entrance for long-term re-intervention. The entrance is small in size and will not affect the structural stability of the coated stent body 10, nor will it have the risk of thrombosis in the long term. Through this entrance, convenient catheter guidewire operations can be performed between the coated stent body 10 and the blood vessel wall and in the cavity of the coated stent body 10 (such as sending substances such as spring coils and tissue glue between the outer layer of the aorta coated stent and the inner layer of the autologous blood vessel to prevent long-term internal leakage). Or it can be used to perfuse antibacterial drugs into the outer layer of the stent that is infected in the long term, etc. For small stents, anticoagulant or anti-intimal hyperplasia drugs can also be perfused into the inner layer of the stent. That is to say, in one embodiment, among the multiple docking devices 30, some of the docking devices 30 may not be connected to the drug storage device 20.

[0067] The docking device 30 provided in this embodiment has the interface tube 312, and the interface tube 312 is a Y-shaped tube. After bifurcation, one tube leads to the inside of the coated stent body 10, and the other tube leads to the gap between the outside of the coated stent body 10 and the blood vessel wall. The lower half of the Y-shaped tube (the part before bifurcation) is connected to the outer sleeve 311, and the tube mouth is located at the end of the docking part 32. When the catheter with opposite magnetic poles is "connected" to the docking part 32, the catheter mouth is accurately aligned with the outer mouth of the interface tube 312. The guide wire can be introduced into the Y-shaped tube through the catheter, and the catheter can be followed up to choose whether to enter the stent or outside the stent for further processing under fluoroscopy.

[0068] It is understandable that in the prior art, it is difficult to re-intervene an already implanted covered stent, which is time-consuming, costly, and may not produce satisfactory results. The covered stent 100 provided in this embodiment can effectively reduce the difficulty of docking, thereby reducing the difficulty and time-consuming operation, facilitating long-term re-endovascular surgical intervention, and reducing the trauma and cost of re-operative intervention. In addition, in the prior art, it is impossible to implant a covered stent for infected lesions. For long-term infection of the covered stent, only systemic antibiotic treatment or open surgery for bypass and drainage can be performed, which is very traumatic. The covered stent 100 provided in this embodiment can serve as an interface device for drug administration in the long term. At the same time, the small-diameter covered stent used for peripheral arteries in the prior art has a high probability of restenosis and occlusion in the medium and long term, and can only be intervened by balloon expansion and covered stent intervention in the later stage. The current anticoagulant and anti-intimal hyperplasia drugs cannot provide long-term patency of the covered stent. An interface device that can be used for drug administration in the long term is also needed. The covered stent 100 provided in this embodiment can perfectly solve the above problems.

[0069] As the rate of long-term reoperation for endovascular treatment increases with the large number of endovascular surgeries, the efficiency of re-interventional procedures needs to be improved with the support of new concepts, technologies, and device innovations. The stent graft 100 provided in this embodiment is a concept that provides a long-term access port within the stent. The stent graft 100 facilitates magnetic navigation "docking" of an intraluminal catheter guidewire, facilitating docking for interventional procedures and drug delivery.

[0070] The above description is only an embodiment of the present invention. It should be pointed out that those skilled in the art can make improvements without departing from the creative concept of the present invention, but these improvements all fall within the scope of protection of the present invention.

Claims

1. A stent graft, characterized in that: It includes a stent graft body and a drug storage device; The stent graft body has a flow space with two ends connected; The drug storage device is fixed to the stent graft body, and at least part of the drug storage device is located outside the stent graft body. The drug storage device has a drug storage space inside, and a drug delivery hole is opened on the drug storage device, and the drug delivery hole connects the drug storage space with the external environment; Also included is a docking device; The docking device is fixed to the stent graft body, and a drug replenishing channel is provided on the docking device, and the drug replenishing channel is communicated with the drug storage space; The docking device includes a mounting portion and a docking portion: The mounting portion is fixedly connected to the stent graft body and is located at one end of the stent graft body along the axial direction of the stent graft body; The docking portion is fixed on the mounting portion; The medicine replenishing channel is provided in the mounting portion; The mounting portion includes an outer sleeve, an interface tube and a hemostatic valve; The drug-replenishing channel is surrounded by the interface tube, a portion of the interface tube is disposed in the outer sleeve, another portion of the interface tube extends out of the outer sleeve and is connected to the stent graft body, and the portion of the interface tube located in the outer sleeve is disposed through the outer sleeve; The hemostatic valve is arranged in the interface tube; The docking portion is fixed on the outer sleeve; The interface pipe includes an inner pipe, an inner layer interface pipe, an outer layer interface pipe, a first connecting pipe and a second connecting pipe; The inner tube is located in the outer tube; The inner layer interface tube is in close contact with the inner surface of the stent graft body; The outer interface tube is in contact with the outer surface of the stent graft body, and is connected to the drug storage device; The first connecting pipe connects the inner layer interface pipe and the inner pipe; The second connecting pipe connects the outer interface pipe and the inner pipe; The medicine-tonifying channel is surrounded by the inner tube, the second connecting tube and the outer interface tube; The docking portion is a magnetic docking portion.

2. The stent graft according to claim 1, wherein: The drug storage device is embedded in the film of the stent graft body.

3. The stent graft according to claim 2, wherein: The drug storage device includes an axial drug storage tube and a circumferential drug storage tube; The axial drug storage tube is arranged along the axial direction of the stent graft body; The circumferential drug storage tube is connected to the axial drug storage tube, and the circumferential drug storage tube is arranged along the circumference of the stent graft body; The drug storage space includes a first drug storage space and a second drug storage space, wherein the first drug storage space is opened in the axial drug storage tube, and the second drug storage space is opened in the circumferential drug storage tube, and the second drug storage space is connected to the first drug storage space; The drug administration holes are both provided on the axial drug storage tube and the circumferential drug storage tube.

4. The stent graft according to claim 3, wherein: There are multiple axial drug storage tubes, which are distributed in sequence along the circumference of the stent graft body, and two adjacent axial drug storage tubes are spaced apart from each other.

5. The stent graft according to claim 3 or 4, characterized in that: There are multiple circumferential drug storage tubes, which are distributed in sequence along the axial direction of the stent graft body, and two adjacent circumferential drug storage tubes are spaced apart from each other.

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