A multi-channel micro-injection system

By designing a multi-channel micro-dosing system, the driving parts are used to drive the pipette to move in space on the material platform, realizing multi-channel simultaneous aspiration, dispensing and automatic recovery of the gun tip, which solves the problems of low efficiency and safety hazards of the existing dosing system and improves the accuracy and consistency of dosing.

CN114414829BActive Publication Date: 2025-09-23AUTOBIO LABTEC INSTR CO LTD
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Patent Information

Application Number
CN202210208003.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-03-03
Publication Date
2025-09-23
Estimated Expiration
2042-03-03

AI Technical Summary

Technical Problem

The existing sample addition system is a single-channel design with low efficiency. Manual operation poses safety risks and lacks standardization, making it difficult to ensure the accuracy and consistency of sample addition.

Method used

A multi-channel micro-dosing system is designed, including a pipette, a drive, a material platform and a frame. The drive drives the pipette to move spatially on the material platform, realizing multi-channel simultaneous aspiration and dispensing operations. It is also equipped with a separation component to automatically recycle discarded pipette tips.

Benefits of technology

The sampling efficiency of the sampling system is improved, the accuracy and consistency of the sampling are ensured, and the safety hazards of manual operation are reduced.

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Abstract

The present invention discloses a multi-channel micro-sampling system, comprising a pipette, a drive, a material platform, and a frame. The material platform is equipped with a reagent kit for accommodating reagent solutions, a target plate, a tip box for storing gun tips, and a waste bin for recovering discarded gun tips. The bottom of the pipette is provided with multiple adapters arranged side by side. The drive and material platform are both mounted on the frame. The drive is connected to the pipette to drive the pipette to move spatially above the material platform. The pipette is equipped with a retractable separation member for separating the adapter and the gun tip. By using the multi-channel micro-sampling system provided by the present invention, the sampling efficiency during micro-sampling can be effectively improved.
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Description

Technical Field

[0001] The present invention relates to the technical field of sample transfer and addition, and more particularly to a multi-channel micro-addition system. Background Art

[0002] In various scientific research fields such as biomedicine and chemical engineering, operations such as liquid sample transfer and sample loading are involved. Currently, manual loading is usually used, which takes a long time and has low work efficiency. In addition, due to the uneven technical level of operators, the entire loading process lacks standardization and standardized operation management, and the accuracy of loading position and loading precision cannot be guaranteed, resulting in poor repeatability and consistency of loading. Moreover, many samples contain toxic and corrosive components that can easily corrode the skin and irritate the respiratory system, posing a safety hazard. In addition, conventional automated loading system instruments are all single-channel pipette designs. Although automatic loading operations can be performed normally, the loading efficiency is low and the loading speed is slow.

[0003] In summary, how to improve the spotting efficiency of the sample addition system is an urgent problem to be solved by those skilled in the art. Summary of the Invention

[0004] In view of this, an object of the present invention is to provide a multi-channel micro-sample loading system, which can effectively improve the sampling efficiency of the sample loading system.

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] A multi-channel micro-injection system includes: a pipette, a driving member, a material platform and a frame. The material platform is provided with a reagent kit for accommodating reagent liquid, a target plate, a tip box for storing gun tips and a waste bin for recovering discarded gun tips. The bottom of the pipette is provided with a plurality of adapters distributed side by side. The driving member and the material platform are both provided on the frame. The driving member is connected to the pipette to drive the pipette to move in space above the material platform. The pipette is provided with a retractable separation member for separating the adapter and the gun tip.

[0007] Preferably, it further comprises a fixing member, wherein the fixing member comprises a fixing block provided with a first arc groove, a limiting block provided with a second arc groove, a Z-axis fixing plate connected to the driving member, and a lower supporting plate provided with a third arc groove;

[0008] The fixed block and the limiting block are arranged relative to each other so that the first arc groove and the second arc groove cooperate to clamp the top of the pipette, and the third arc groove is used to clamp with the bottom of the pipette. The Z-axis fixed plate and the pipette are arranged in parallel, and the fixed block, the limiting block and the lower supporting plate are all vertically arranged on the Z-axis fixed plate.

[0009] Preferably, the separation part includes a telescopic motor, a pin and a gun-disengaging limiter provided on the fixing part for limiting the moving range of the pin. A vertical connecting rod and a horizontal push rod are provided in the pipette. The push rod is sleeved on the outer periphery of the adapter. The top of the connecting rod is provided with a through hole for engaging with the pin. The bottom of the connecting rod is connected to the push rod, and the pin is connected to the telescopic end of the telescopic motor.

[0010] Preferably, the driving member includes an X guide rail arranged along the X-axis direction of the frame, a Y guide rail arranged along the Y-axis direction of the frame, a Z guide rail arranged along the Z-axis direction of the frame, a first driving part for driving the Y guide rail to slide along the X guide rail, a second driving part for driving the Z guide rail to slide along the Y guide rail, and a third driving part for driving the pipette to slide along the Z guide rail, the Y guide rail and the X guide rail are slidably connected, the Z guide rail and the Y guide rail are slidably connected, and the pipette and the Z guide rail are slidably connected.

[0011] Preferably, the first driving part, the second driving part and the third driving part are all synchronous belt driving structures, screw nut driving structures or gear rack structures.

[0012] Preferably, the material platform includes a first platform for placing the target plate and the reagent kit and a second platform for placing the gun tip box, the second platform and the first platform are arranged parallel to each other, and the position of the second platform is lower than that of the first platform, so that the top of the target plate, the top of the reagent kit and the top of the gun tip box are flush.

[0013] Preferably, the first platform is provided with a plurality of mounting grooves for fixing the target plate, a magnet for attracting the target plate, and a support plate for supporting the reagent kit, and each of the mounting grooves is provided with the magnet.

[0014] Preferably, the second platform is provided with a first positioning block, a second positioning block, a first tightening spring and a second tightening spring. The first positioning block and the first tightening spring cooperate to clamp the horizontal sides of the gun tip box, and the second positioning block and the second tightening spring cooperate to clamp the vertical sides of the gun tip box.

[0015] Preferably, the side of the second platform is provided with a positioning pin used as an installation reference.

[0016] Preferably, the waste bin and a waste limiting member for limiting the position of the waste bin are provided on the side of the second platform, and the waste bin is provided with a handle.

[0017] When using the multi-channel micro-sampling system provided by the present invention, the material platform and the driving member are both arranged on the frame, and the driving member is connected to the pipette so that the pipette moves in space above the material platform. When performing the sampling operation, the driving member can be used to drive the pipette to move so that the pipette moves to the top of the gun tip box, and then the pipette is moved downward so that multiple adapters distributed side by side are simultaneously fixed with the gun tip, and then the pipette is controlled to move upward, and then the pipette is controlled to move to the top of the reagent box, and the gun tip is used to perform the liquid collection operation. After the liquid collection operation is completed, the pipette is controlled to move to the top of the target plate for the sampling operation, and finally, the driving member can be used to drive the pipette to move to the waste bin, and the separation member can be controlled to extend downward to separate the adapter and the gun tip, and the discarded gun tip can fall into the waste bin for recycling, so that the adapter can perform the next sampling and sampling operation.

[0018] In summary, the multi-channel micro-injection system provided by the present invention can effectively improve the sampling efficiency during micro-injection. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are merely embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the provided drawings without paying any creative work.

[0020] Figure 1 This is a schematic structural diagram of the multi-channel micro-injection system provided by the present invention;

[0021] Figure 2 for Figure 1 The main view;

[0022] Figure 3 for Figure 1 A top view of

[0023] Figure 4 Schematic diagram of the structure of the first platform;

[0024] Figure 5 is a structural diagram of the second platform;

[0025] Figure 6 Schematic diagram of the structure of the support plate;

[0026] Figure 7 is a top view of the first platform;

[0027] Figure 8 is a structural diagram of a fixing part;

[0028] Figure 9 is a top view of the fixing member;

[0029] Figure 10 is the main view of the fixing part;

[0030] Figure 11 is a side view of the fixing member;

[0031] Figure 12 Schematic diagram of the internal structure of the pipette;

[0032] Figure 13 Schematic diagram of the structure of the pipette and separation parts.

[0033] Figures 1-13 middle:

[0034] 1 is the pipette, 2 is the drive part, 3 is the material platform, 4 is the frame, 5 is the reagent box, 6 is the target plate, 7 is the gun head box, 8 is the waste bin, 9 is the adapter, 10 is the separation part, 11 is the fixing part, 12 is the fixing block, 13 is the limit block, 14 is the Z-axis fixing plate, 15 is the lower support plate, 16 is the telescopic motor, 17 is the pin, 18 is the gun removal limit part, 19 is the connecting rod, 20 is the push rod, 21 is the X guide rail, and 22 is the Y guide rail. , 23 is the Z guide rail, 24 is the first platform, 25 is the second platform, 26 is the mounting groove, 27 is the magnet, 28 is the support plate, 29 is the positioning pin, 30 is the waste limiter, 31 is the handle, 32 is the hand-avoidance position, 33 is the first positioning block, 34 is the second positioning block, 35 is the first tightening spring piece, 36 is the second tightening spring piece, 37 is the support column, 38 is the first arc groove, 39 is the second arc groove, and 40 is the third arc groove. DETAILED DESCRIPTION

[0035] The following will clearly and completely describe the technical solutions in the embodiments of the present invention in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0036] The core of the present invention is to provide a multi-channel micro-sample addition system, which can effectively improve the sampling efficiency of the sample addition system.

[0037] Please refer to Figures 1 to 13 .

[0038] This specific embodiment provides a multi-channel micro-injection system, including: a pipette 1, a driving member 2, a material platform 3 and a frame 4. The material platform 3 is provided with a reagent kit 5 for accommodating reagent liquid, a target plate 6, a gun tip box 7 for storing gun tips and a waste bin 8 for recycling discarded gun tips. The bottom of the pipette 1 is provided with a plurality of adapters 9 distributed side by side. The driving member 2 and the material platform 3 are both provided on the frame 4. The driving member 2 and the pipette 1 are connected to drive the pipette 1 to move in space above the material platform 3. The pipette 1 is provided with a retractable separation member 10 for separating the adapter 9 and the gun tip.

[0039] It should be noted that the bottom of the pipette 1 is provided with multiple adapters 9 distributed side by side, which means that the pipette 1 is a multi-channel pipette 1. This pipette 1 is a standard part and can support aspiration and dispensing operations of 1ul-12.5ul liquid volume. In addition, the distance between the gun tip and the adapter 9 is adjustable, the minimum distance can be set to 3mm, and the maximum distance can be set to 9mm. This pipette 1 can perform multi-channel simultaneous aspiration and dispensing operations to improve the efficiency of sampling and spotting operations.

[0040] During actual use, the shape, structure, size, material, position, etc. of the pipette 1, the driving member 2, the material platform 3 and the frame 4 can be determined according to actual conditions and actual needs.

[0041] When using the multi-channel micro-injection system provided by the present invention, the material platform 3 and the driving member 2 are both arranged on the frame 4. The driving member 2 is connected to the pipette 1 so that the pipette 1 can move spatially above the material platform 3. During the injection operation, the driving member 2 can be used to drive the pipette 1 to move the pipette 1 to the top of the gun tip box 7. The pipette 1 is then moved downward so that multiple adapters 9 arranged side by side are simultaneously engaged and fixed with the gun tips. The pipette 1 is then controlled to move upward. After that, the pipette 1 is controlled to move to the top of the reagent box 5. The gun tips are used to perform the liquid extraction operation. After the liquid extraction operation is completed, the pipette 1 is controlled to move to the top of multiple target plates 6 in sequence for sample or liquid separation operations. Finally, the driving member 2 can be used to drive the pipette 1 to the waste bin 8, and the separation member 10 is controlled to extend downward to separate the adapter 9 from the gun tip. The discarded gun tips can fall into the waste bin 8 for recycling, so that the adapter 9 can be used for the next sampling and injection operation.

[0042] In summary, the multi-channel micro-injection system provided by the present invention can effectively improve the sampling efficiency of the injection system.

[0043] On the basis of the above embodiment, preferably, it also includes a fixing member 11, which includes a fixing block 12 provided with a first circular arc groove 38, a limiting block 13 provided with a second circular arc groove 39, a Z-axis fixing plate 14 connected to the driving member 2, and a lower supporting plate 15 provided with a third circular arc groove 40; the fixing block 12 and the limiting block 13 are arranged relative to each other, so that the first circular arc groove 38 and the second circular arc groove 39 cooperate to clamp the top of the pipette 1, and the third circular arc groove 40 is used to clamp with the bottom of the pipette 1, the Z-axis fixing plate 14 and the pipette 1 are arranged parallel to each other, and the fixing block 12, the limiting block 13 and the lower supporting plate 15 are all arranged vertically on the Z-axis fixing plate 14.

[0044] It should be noted that the original pipette 1 is usually handheld and therefore does not have an adapter mounting hole. Since the working environment of this device is to dispense liquid onto a target plate 6, which is a flat surface, high sample dispensing accuracy is required, and therefore the installation accuracy requirements of the pipette 1 are also high. The fixing member 11 can ensure high-precision installation operation of the pipette 1 without an adapter mounting hole.

[0045] It should also be noted that, when the first circular groove and the second circular arc groove 39 are locked, the two circular arc grooves cooperate with each other to form an arc that matches the circular arc shell at the top of the pipette 1. This arc is tightly matched with the circular arc shell at the top of the pipette 1, realizing a clamping function, so that the pipette 1 does not move left and right. The lower supporting plate 15 is provided with a third circular arc groove 40, the inner side of which is an arc limit edge that matches the circular arc at the bottom of the pipette 1. After the pipette 1 is placed on the lower supporting plate 15, the pipette 1 can be prevented from moving downward, thereby ensuring that the pipette 1 does not move up and down.

[0046] During actual use, the shape, structure, size, material, position, etc. of the fixing block 12, the limiting block 13, the Z-axis fixing plate 14 and the lower supporting plate 15 can be determined according to actual conditions and actual needs.

[0047] Preferably, the separation part 10 includes a telescopic motor 16, a pin 17 and a gun-disengaging limiter 18 provided on the fixing part 11 for limiting the moving range of the pin 17. A vertical connecting rod 19 and a horizontal push rod 20 are provided in the pipette 1. The push rod 20 is sleeved on the outer periphery of the adapter 9. The top of the connecting rod 19 is provided with a through hole for engaging with the pin 17. The bottom of the connecting rod 19 is connected to the push rod 20, and the pin 17 is connected to the telescopic end of the telescopic motor 16.

[0048] It should be noted that, when it is necessary to separate the adapter 9 and the gun tip, the telescopic motor 16 can be controlled to operate. When the telescopic motor 16 is pushed down, the telescopic end of the telescopic motor 16 can push the pin 17 downwards. The pin 17 can be inserted into the through hole at the top of the connecting rod 19. Since the bottom of the connecting rod 19 and the push rod 20 are fixedly connected, when the connecting rod 19 is pushed down, the push rod 20 also pushes down. When it is necessary to utilize the pipette 1 to perform the liquid-pointing operation, the pipette 1 can be moved to the top of the gun tip box 7, and then the adapter 9 is inserted into the gun tip inside to achieve a close fit between the adapter 9 and the gun tip. The inner surface of the gun tip and the outer surface of the adapter 9 can be tightly matched to achieve the action of taking out the gun tip. After completing the sample-pointing operation, it is necessary to utilize the separating member 10 to take off the gun tip. That is, the telescopic motor 16 is controlled to operate, and the connecting rod 19 and the push rod 20 are pushed down to push the gun tip away from the adapter 9, so as to achieve the automatic take-off gun tip function.

[0049] In actual use, the shape, structure, size, material, position, etc. of the telescopic motor 16, the pin 17 and the gun release limiter 18 can be determined according to actual conditions and actual needs.

[0050] Preferably, the driving member 2 includes an X-rail 21 arranged along the X-axis direction of the frame 4, a Y-rail 22 arranged along the Y-axis direction of the frame 4, a Z-rail 23 arranged along the Z-axis direction of the frame 4, a first driving portion for driving the Y-rail 22 to slide along the X-rail 21, a second driving portion for driving the Z-rail 23 to slide along the Y-rail 22, and a third driving portion for driving the pipette 1 to slide along the Z-rail 23. The Y-rail 22 is slidably connected to the X-rail 21, the Z-rail 23 is slidably connected to the Y-rail 22, and the pipette 1 is slidably connected to the Z-rail 23. That is, the driving member 2 can drive the pipette 1 to achieve three-dimensional spatial movement. Through the coordinated operation of the first driving portion, the second driving portion, and the third driving portion, the pipette 1 can be moved between a tip removal position, a reagent removal position, a liquid dispensing position, and a tip removal position, thereby realizing automated sampling and dispensing operations of the pipette 1.

[0051] Preferably, the first drive unit, the second drive unit and the third drive unit are all synchronous belt drive structures, screw nut drive structures or gear rack structures, so that the Y guide rail 22 slides back and forth along the X guide rail 21, the Z guide rail 23 slides back and forth along the Y guide rail 22, and the pipette 1 slides back and forth along the Z guide rail 23.

[0052] Preferably, the material platform 3 includes a first platform 24 for placing the target plate 6 and the reagent reagent 5 and a second platform 25 for placing the gun tip box 7. The second platform 25 and the first platform 24 are arranged in parallel, and the position of the second platform 25 is lower than that of the first platform 24 so that the top of the target plate 6, the top of the reagent reagent 5 and the top of the gun tip box 7 are flush.

[0053] It should be noted that, since the heights of the gun tip box 7, the reagent box 5 and the target plate 6 are inconsistent, in order to ensure that the top of the target plate 6, the top of the reagent box 5 and the top of the gun tip box 7 are flush, so that the lifting operation can be reduced when the driving member 2 moves in three-dimensional space, a first platform 24 and a second platform 25 of uneven heights are provided respectively, and a support column 37 can be set between the first platform 24 and the second platform 25. The target plate 6 and the reagent box 5 are placed on the first platform 24 to ensure that the instrument can efficiently spot samples. In addition, the capacity of the first platform 24 that can hold multiple target plates 6 and the reagent box 5 needs to meet the spotting usage of multiple target plates 6.

[0054] During actual use, the shape, structure, size, material, position, etc. of the first platform 24 and the second platform 25 can be determined according to actual conditions and actual needs.

[0055] Preferably, the first platform 24 is provided with a plurality of mounting grooves 26 for fixing the target plate 6, a magnet 27 for attracting the target plate 6, and a support plate 28 for supporting the reagent kit 5. Each mounting groove 26 is provided with a magnet 27. The structure is as follows: Figure 7 As shown. Therefore, the target plate 6 can be placed in the corresponding mounting groove 26, and the target plate 6 can be tightly attracted by the magnet 27 in the mounting groove 26 to prevent the target plate 6 from being misplaced or shifted during use. A hand-safe position 32 can be provided between adjacent mounting grooves 26 to facilitate the insertion or removal of the target plate 6.

[0056] Preferably, the second platform 25 is provided with a first positioning block 33, a second positioning block 34, a first tightening spring 35 and a second tightening spring 36. The first positioning block 33 and the first tightening spring 35 cooperate to clamp the horizontal sides of the gun tip box 7, and the second positioning block 34 and the second tightening spring 36 cooperate to clamp the vertical sides of the gun tip box 7.

[0057] It should be noted that when the gun tip box 7 is placed on the second platform 25, a positioning structure is specifically provided to ensure the positioning accuracy of the gun tip box 7. The positioning structure includes a first positioning block 33, a second positioning block 34, a first tightening spring 35, and a second tightening spring 36. The first positioning block 33 and the first tightening spring 35 ensure the accurate positioning of the gun tip box 7 in the X direction, while the second positioning block 34 and the second tightening spring 36 ensure the accurate positioning of the gun tip box 7 in the Y direction. The upper portions of the positioning blocks and the tightening springs can each be provided with an inclined surface to guide the gun tip box 7, facilitating installation and removal of the gun tip box 7.

[0058] Preferably, a positioning pin 29 serving as an installation reference is provided on the side of the second platform 25. The positioning pin 29 serves as the installation reference edge of the second platform 25, which can ensure that the relative positions of the material platform 3 and the driving member 2 are accurate.

[0059] Preferably, a waste bin 8 and a waste stopper 30 for limiting the position of the waste bin 8 are provided on the side of the second platform 25. The waste bin 8 is also provided with a handle 31. The waste stopper 30 effectively fixes the position of the waste bin 8, ensuring that discarded gun tips fall accurately into the waste bin 8. The waste bin 8 is provided with a handle 31 to facilitate the operator's replacement of the waste bin 8.

[0060] It should be noted that the first positioning block 33 and the second positioning block 34, the first tightening spring piece 35 and the second tightening spring piece 36, the first platform 24 and the second platform 25, the first driving part and the second driving part and the third driving part, the first arc groove 38 and the second arc groove 39 and the third arc groove 40 mentioned in this application document, among which the first, second and third are only for distinguishing the different positions and there is no order of precedence.

[0061] In addition, it should be noted that the orientations or positional relationships indicated by "X", "Y", "Z", etc. in this application are based on the orientations or positional relationships shown in the accompanying drawings and are only for the purpose of simplifying the description and facilitating understanding. They do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, they should not be understood as limiting the present invention.

[0062] The various embodiments in this specification are described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same or similar parts between the various embodiments can be referenced to each other. Any combination of all the embodiments provided by the present invention is within the scope of protection of this invention and will not be described in detail here.

[0063] The above is a detailed introduction to the multi-channel micro-injection system provided by the present invention. Specific examples are used herein to illustrate the principles and implementation methods of the present invention. The description of the above embodiments is only used to help understand the method of the present invention and its core concept. It should be pointed out that for ordinary technicians in this technical field, without departing from the principles of the present invention, the present invention can also be improved and modified in a number of ways, and these improvements and modifications also fall within the scope of protection of the claims of the present invention.

Claims

1. A multi-channel micro-injection system, characterized in that: include: A pipette (1), a driving member (2), a material platform (3) and a frame (4), wherein the material platform (3) is provided with a reagent kit (5) for accommodating a reagent solution, a target plate (6), a tip box (7) for storing a gun tip and a waste bin (8) for recovering discarded gun tips, a plurality of adapters (9) arranged side by side are provided at the bottom of the pipette (1), the driving member (2) and the material platform (3) are both provided on the frame (4), the driving member (2) and the pipette (1) are connected to drive the pipette (1) to move in space above the material platform (3), and the pipette (1) is provided with a retractable separation member (10) for separating the adapter (9) and the gun tip; It also includes a fixing member (11), the fixing member (11) includes a fixing block (12) provided with a first circular arc groove (38), a limiting block (13) provided with a second circular arc groove (39), a Z-axis fixing plate (14) connected to the driving member (2), and a lower supporting plate (15) provided with a third circular arc groove (40); the fixing block (12) and the limiting block (13) are arranged relative to each other so that the first circular arc groove (38) and the second circular arc groove (39) cooperate to clamp the top of the pipette (1), the third circular arc groove (40) is used to engage with the bottom of the pipette (1), the Z-axis fixing plate (14) and the pipette (1) are arranged in parallel, and the fixing block (12), the limiting block (13) and the lower supporting plate (15) are all arranged vertically on the Z-axis fixing plate (14); The separating member (10) includes a telescopic motor (16) provided on the fixing member (11), a pin (17), and a gun-disengaging limiter (18) for limiting the moving range of the pin (17). A vertical connecting rod (19) and a horizontal push rod (20) are provided in the pipette (1). The push rod (20) is sleeved on the outer periphery of the adapter (9). The top of the connecting rod (19) is provided with a through hole for engaging with the pin (17). The bottom of the connecting rod (19) is connected to the push rod (20), and the pin (17) is connected to the telescopic end of the telescopic motor (16).

2. The multi-channel micro-injection system according to claim 1, characterized in that: The driving member (2) includes an X guide rail (21) arranged along the X-axis direction of the frame (4), a Y guide rail (22) arranged along the Y-axis direction of the frame (4), a Z guide rail (23) arranged along the Z-axis direction of the frame (4), a first driving portion for driving the Y guide rail (22) to slide along the X guide rail (21), a second driving portion for driving the Z guide rail (23) to slide along the Y guide rail (22), and a third driving portion for driving the pipette (1) to slide along the Z guide rail (23), wherein the Y guide rail (22) is slidably connected to the X guide rail (21), the Z guide rail (23) is slidably connected to the Y guide rail (22), and the pipette (1) is slidably connected to the Z guide rail (23).

3. The multi-channel micro-injection system according to claim 2, characterized in that: The first driving part, the second driving part and the third driving part are all synchronous belt driving structures, screw nut driving structures or gear rack structures.

4. The multi-channel micro-injection system according to any one of claims 1 to 3, characterized in that: The material platform (3) includes a first platform (24) for placing the target plate (6) and the reagent kit (5) and a second platform (25) for placing the gun tip box (7). The second platform (25) and the first platform (24) are arranged in parallel, and the position of the second platform (25) is lower than that of the first platform (24) so ​​that the top of the target plate (6), the top of the reagent kit (5) and the top of the gun tip box (7) are flush.

5. The multi-channel micro-injection system according to claim 4, characterized in that: The first platform (24) is provided with a plurality of mounting grooves (26) for fixing the target plate (6), a magnet (27) for attracting the target plate (6), and a support plate (28) for supporting the reagent kit (5), and each mounting groove (26) is provided with the magnet (27).

6. The multi-channel micro-injection system according to claim 4, characterized in that: The second platform (25) is provided with a first positioning block (33), a second positioning block (34), a first tightening spring (35) and a second tightening spring (36); the first positioning block (33) and the first tightening spring (35) cooperate to clamp the horizontal sides of the gun tip box (7); the second positioning block (34) and the second tightening spring (36) cooperate to clamp the vertical sides of the gun tip box (7).

7. The multi-channel micro-injection system according to claim 4, characterized in that: The side of the second platform (25) is provided with a positioning pin (29) used as a mounting reference.

8. The multi-channel micro-injection system according to claim 4, characterized in that: The waste bin (8) and a waste limiting member (30) for limiting the position of the waste bin (8) are provided on the side of the second platform (25), and the waste bin (8) is provided with a handle (31).

Citation Information

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