Microwave radiation system for microwave whole body hyperthermia and microwave whole body hyperthermia equipment

Abstract

The present invention relates to a microwave radiation system for microwave whole body hyperthermia, comprising a microwave source and a whole body radiation device. The microwave source is used to generate and output microwave energy; the whole body radiation device is used to radiate the microwave energy output by the microwave source to the whole body of the target human body; the whole body radiation device comprises a cylindrical reflection surface, a first antenna array extending along the axial direction of the cylindrical reflection surface, and a second antenna array extending along the axial direction of the cylindrical reflection surface, and the microwave source is connected to the first antenna array and the second antenna array respectively. Compared with the prior art, the present invention solves the problem that the radiation range of the existing microwave radiation head is concentrated and the radiation intensity decays quickly from the center to the edge within the radiation range, so that microwaves can be radiated relatively evenly to the target heating area. The hyperthermia treatment equipment of the present invention can be used to improve the body's immunity, improve blood circulation, and treat cancer patients with extensive metastasis who are not suitable for radiotherapy, chemotherapy, local hyperthermia, etc.

Description

Technical Field

[0001] The invention belongs to the technical field of medical equipment, relates to human body heating treatment technology, and in particular to a device for performing whole body heating treatment on a human body. Background Art

[0002] Hyperthermia therapy is a method of preventing and treating diseases by artificially raising the body temperature in order to kill diseased cells or activate the body's immune system. This method has the effects of activating immune function, improving basal metabolism, improving blood circulation, assisting in radiotherapy and chemotherapy, and selectively killing tumor cells.

[0003] The existing heat therapy methods include biological method, extracorporeal circulation warming method, surface conduction warming method, and external radiation method. Among them, the biological method is to induce heat production in the body by injecting toxins and bacteria into the patient's body. Since the fever time and temperature are uncontrollable, there are great safety issues; the extracorporeal circulation warming method is to use a blood pump to draw blood out of the body, heat it to a certain temperature and then return it to the body. It is an invasive treatment method with expensive equipment and cost, and requires systemic anticoagulation, which is very harmful to the human body. The surface conduction warming method is a treatment method that uses a heat source medium to directly contact the human body to transfer heat to the human body, such as warm blanket wrapping method, hot water bath method, etc., because it cannot quickly and effectively increase the core temperature of the heated object, it is difficult to achieve the desired effect.

[0004] The extracorporeal radiation method is a thermal therapy method that uses electromagnetic waves that are penetrating to human tissue as radiation signals to irradiate the human body from the outside to increase the temperature of human tissue. The radiation sources are mainly infrared and microwave. This method uses the penetrating nature of the radiation signal to directly heat the internal tissues of the human body. Compared with the heating method of heating the skin and then conducting it inward, it is easier to reach the target temperature. In addition, this method is a non-invasive therapy with relatively low risks and few side effects. Therefore, the extracorporeal radiation method is currently a relatively important method used in thermal therapy.

[0005] However, since the in vitro radiation method uses the penetrating power of electromagnetic waves to directly heat the internal tissues of the human body, it is difficult to monitor the temperature of the target part of the body without invading the human body. Although it is possible to determine the radiation power and radiation time of a specific device to achieve the target effect through repeated experiments, it is still difficult to grasp the treatment effect due to individual differences in patients, and there are certain risks. In order to prevent and control risks, the radiation power and radiation time of the device must be set below the ideal value obtained from the experimental conclusions, resulting in difficulty in achieving the target treatment effect.

[0006] An optional solution to this problem is to evenly heat the patient's entire body, then monitor the body temperature using conventional temperature detection methods (detecting oral temperature, submerged temperature, anal temperature, etc.), and then intelligently control the output power and working time of the thermal therapy equipment based on the real-time body temperature, so that the human body can be accurately controlled at the target temperature, thereby achieving the ideal thermal therapy goal while effectively preventing and controlling risks.

[0007] The difficulty of this solution lies in how to achieve uniform heating of the human body.

[0008] In order to solve the problem of how to achieve uniform heating of the human body, the solution adopted by infrared whole body thermal therapy equipment is mainly to evenly arrange infrared radiators, such as the thermal therapy devices disclosed in Chinese patents with publication numbers CN2621638 and CN2618571. There are also devices that, based on the uniform arrangement of infrared radiators, further enhance the uniformity of infrared rays irradiated to the human body through diffuse reflection based on the optical properties of infrared rays, such as the infrared heat source whole body thermal therapy machine disclosed in Chinese patent application with publication number CN109985312A.

[0009] However, infrared rays have a weak ability to penetrate human tissue. Even near infrared rays (or short-wave infrared rays, with a wavelength of 0.76 to 1.5 μm) can only penetrate 5 to 10 mm into human tissue (Design and Implementation of Photoelectric Protection Control, Chen Kuixu, Graduation Project of Nanchong Vocational and Technical College, November 7, 2013). Therefore, the use of infrared thermotherapy devices for whole-body hyperthermia has the problem of serious longitudinal uneven heating. There is a situation where the monitored human body temperature is still relatively low, but the surface temperature has exceeded the skin's tolerance limit. If the temperature is too high, it is easy to cause burns on the surface of the body. In practice, in order to prevent burns on the surface of the body, only low-power slow heating can be used. Therefore, the whole-body hyperthermia using infrared radiation is very slow.

[0010] Compared with infrared rays, which have poor penetration into the human body, microwaves have better penetration into the human body and can penetrate relatively deeply into the human body. Using microwaves to irradiate the human body for hyperthermia can effectively solve the problem of severe uneven longitudinal heating. However, microwave hyperthermia equipment has not yet provided an effective solution to the problem of how to achieve uniform heating of the entire human body. Precisely because of this, the microwave hyperthermia devices currently available on the market are all devices used for local hyperthermia (such as the BSD-400 equipment and BSD-2000 hyperthermia machine produced by a US company; the RF-8 hyperthermia machine produced by a Japanese company; the UHR-2000 hyperthermia machine produced by a Hunan company. The SR1000 tumor microwave hyperthermia system of a Shenzhen company, etc.).

[0011] Existing microwave hyperthermia radiation heads have the characteristics of narrow beam, strong directionality, concentrated radiation range, and fast radiation intensity decay from the center to the edge within the radiation range. They can be used for local hyperthermia, but are difficult to use for whole-body hyperthermia.

[0012] If we refer to the solution of evenly arranging infrared radiators given by infrared whole body hyperthermia equipment and evenly arrange a large number of existing microwave hyperthermia radiation heads to achieve microwave radiation whole body hyperthermia, on the one hand, this will seriously increase the cost of the equipment. On the other hand, due to the characteristics of the microwave antenna's field strength distribution within the radiation range, which is strong in the center and quickly weakens toward the edge, there will be a problem that the center temperature of the irradiation area of ​​each radiation head is high, while the edge temperature is relatively low. This problem will result in a situation where the overall body temperature has not yet reached the treatment requirements, while the center of the irradiation area of ​​each radiation head has exceeded the tolerance limit of human tissue.

[0013] How to achieve whole-body hyperthermia by microwave radiation is a technical problem that has not yet been solved. Summary of the invention

[0014] The purpose of the present invention is to provide a microwave whole body hyperthermia device which is based on the in vitro radiation method and adopts a microwave radiation source to achieve safe and effective whole body hyperthermia without intervening in the human body, in view of the technical status quo that microwave whole body hyperthermia has not been realized in the prior art. The device can overcome the shortcomings of the existing infrared whole body hyperthermia method, avoid the defect that a single or local electromagnetic wave heat source easily causes fat nodules, and achieve the purpose of rapid, stable, uniform, personalized and precise heating of deep tissues throughout the body.

[0015] The present invention first proposes a microwave radiation system for microwave whole body hyperthermia, comprising:

[0016] A microwave source, used for generating and outputting microwave energy;

[0017] A whole body radiation device, used to radiate the microwave energy output by the microwave source to the whole body of the target human body;

[0018] The whole body radiation device comprises a cylindrical reflecting surface, a first antenna array extending along the axial direction of the cylindrical reflecting surface, and a second antenna array extending along the axial direction of the cylindrical reflecting surface, and the microwave source is connected to the first antenna array and the second antenna array respectively;

[0019] The cylindrical reflecting surface is arranged around the radiation area, and the cylindrical reflecting surface is smooth and has no corners along the circumferential direction;

[0020] The first antenna array is arranged above the target human body area inside the cylindrical reflecting surface, and the second antenna array is arranged below the target human body area inside the cylindrical reflecting surface.

[0021] The radiation direction of the first antenna array is downward, the first antenna array is composed of at least one group of directional antenna units, each group of directional antenna units constituting the first antenna array is arranged in a straight line along the axial direction of the cylindrical reflective surface, the radiation directions of the directional antenna units are the same, and the radial cross-section radiation angle of the first antenna array is greater than the angle corresponding to the target human body area;

[0022] The second antenna array radiates upward. The second antenna array is composed of at least one group of directional antenna units. Each group of directional antenna units constituting the second antenna array is arranged in a straight line along the axial direction of the cylindrical reflecting surface. The radiation directions of the directional antenna units are the same. The radial cross-section radiation angle of the second antenna array is greater than the angle corresponding to the target human body area.

[0023] Since the field strength in the radiation area (sector area) of the directional antenna decreases from the center line (90 degree direction) to the two sides (0 degree and 180 degree directions), and the cross-sectional shape of the human body is approximately elliptical, the result is that on the cross-sectional area of ​​the human body, the beam close to the center line, which is originally relatively stronger, enters the human body at a smaller inclination angle to form a greater radiation intensity, and the beam far from the center line, which is originally relatively weaker, enters the human body at a larger inclination angle to form a smaller radiation intensity. The linear antenna array designed by the present invention has a radial cross-sectional radiation range larger than the target human body area, and the radiated beams include a direct beam directly irradiated on the target human body area and a supplementary beam not directly irradiated on the target human body area. The supplementary beam is reflected by a specially designed cylindrical reflective surface to supplement the area in the target human body area where the radiation intensity formed by the direct beam is smaller, so that the area reaches a radiation intensity close to that of the strong radiation area, and finally realizes relatively uniform microwave radiation to the target human body area.

[0024] In addition, the setting of the cylindrical reflective surface also prevents the leakage of radiation signals, realizes the full utilization of radiation energy, effectively reduces the power of the radiation source used, and achieves the effect of energy saving and environmental protection.

[0025] Furthermore, the microwave whole body radiation device also includes an antenna array arranged on the side of the target human body area. Adding the antenna array on the side of the target human body area can increase the density of microwave radiation, and at the same time, the radiation beam is more in line with the shape of the human body, further increasing the uniformity of the radiation intensity, promoting rapid whole body heating with lower power, and increasing uniformity and safety.

[0026] Furthermore, the first antenna array and the second antenna array are parallel to each other and aligned vertically.

[0027] Furthermore, microwave shielding structures are provided at both ends of the cylindrical reflective surface. The shielding structures at both ends and the cylindrical reflective surface together form a closed shielding space to prevent electromagnetic wave leakage from causing energy waste and electromagnetic radiation pollution.

[0028] Furthermore, the cross-sectional shape of the cylindrical reflecting surface is circular or elliptical.

[0029] Furthermore, the radiation area is formed in a cabin, the side wall of the cabin includes an inner shielding layer and an outer shell, and the cylindrical reflecting surface is formed on the inner side surface of the inner shielding layer of the cabin.

[0030] The two ends of the cabin are provided with microwave shielding end plates, and the microwave shielding end plates at the two ends of the cabin are sealed and connected with the inner shielding layer of the cabin side wall to form the inner shielding body of the cabin. The sealing mentioned herein refers to the sealing of microwave signals. Preferably, the sealing is achieved by setting a sealing strip with a shielding effect on microwave signals at the joint.

[0031] Furthermore, an opening for a human body to enter and exit the cabin is provided on the microwave shielding end plate at one end of the cabin, and a shielding curtain is provided at the opening.

[0032] Furthermore, the antenna array is a linear microstrip antenna array, the antenna units constituting the antenna array are patch antenna units, the antenna units are U-shaped structures with an opening direction equal to the array direction, and the feed point is located at the middle connection point of the U-shaped structure. The U-shaped openings of two adjacent antenna units are in opposite directions, and the antenna units constituting a microstrip antenna array are evenly arranged with the center of the C-shaped part of the U-shaped structure as a reference point, and the U-shaped openings of the antenna units at both ends of the antenna array face inward. The two sides of the U-shaped structure are of unequal length, and the long sides and short sides of the two antenna units with opposite openings correspond to each other in an alternating manner.

[0033] The present invention further proposes a microwave whole body hyperthermia treatment device, comprising a control unit, a human-computer interaction unit, an alarm unit, a microwave radiation system, and a monitoring system.

[0034] The human-computer interaction unit is used to accept operation instructions and output relevant information;

[0035] The monitoring system includes a human vital signs monitoring unit and an equipment operation status monitoring unit;

[0036] The human vital sign monitoring unit includes a vital sign signal acquisition module and a group of human vital sign sensors respectively connected to the vital sign signal acquisition module, the vital sign signal acquisition module respectively acquires signals from each human vital sign sensor and outputs them to the control unit;

[0037] The equipment operation status monitoring unit includes an operation status signal acquisition module and a group of operation status sensors respectively connected to the operation status signal acquisition module, and the operation status signal acquisition module respectively acquires signals from each operation status sensor and outputs them to the control unit;

[0038] The microwave radiation system comprises a microwave source for generating and outputting microwave energy, a cabin for accommodating a radiation target, and a whole body radiation device arranged in the cabin for radiating the microwave energy outputted by the microwave source to the whole body of the target human body;

[0039] The control unit receives the instruction sent by the human-computer interaction unit and executes the corresponding control function according to the instruction;

[0040] The control unit receives the real-time human vital sign parameters sent by the human vital sign monitoring unit and the real-time equipment operation status sent by the equipment operation status monitoring unit, and selectively sends them to the human-computer interaction unit for external output, while monitoring each human vital sign parameter. When a human vital sign parameter exceeds a preset threshold value, the alarm unit is controlled to alarm externally;

[0041] The control unit adjusts the output power of the microwave source in real time or controls it to stop working according to the monitoring result of the human vital sign monitoring unit;

[0042] The control unit controls the operation of the equipment in a preset manner according to the monitoring result of the equipment operation status monitoring unit.

[0043] The whole body radiation device comprises a cylindrical reflecting surface formed on the side wall of the cabin, and antenna arrays respectively arranged above and below the target human body area in the cylindrical reflecting surface, wherein the microwave source is connected to the antenna array via a feeder line; the antenna array extends along the axial direction of the cylindrical reflecting surface;

[0044] The cylindrical reflecting surface is smooth and has no corners along the circumferential direction;

[0045] The antenna array is composed of at least one group of directional antenna units, each group of directional antenna units is arranged in a straight line along the axial direction of the cylindrical reflecting surface, the radiation directions of the directional antenna units are the same, and the radial cross-sectional radiation angle of the antenna array is greater than the angle corresponding to the target human body area.

[0046] Furthermore, the microwave whole body radiation device also includes an antenna array arranged on the side of the target human body area.

[0047] Furthermore, microwave shielding structures are provided at both ends of the cabin body, and the shielding structures at both ends and the cylindrical reflecting surface together form a closed shielding space.

[0048] Furthermore, the cross-sectional shape of the cabin is circular or elliptical.

[0049] Furthermore, the side wall of the cabin body includes an inner shielding layer and an outer shell body, and the cylindrical reflecting surface is formed on the inner side surface of the inner shielding layer of the cabin body.

[0050] The two ends of the cabin body are provided with microwave shielding end plates, and the microwave shielding end plates at the two ends of the cabin body are sealed and connected with the inner shielding layer of the cabin body side wall to form the inner shielding body of the cabin body.

[0051] Furthermore, an opening for a human body to enter and exit the cabin is provided on the microwave shielding end plate at one end of the cabin, and a shielding curtain is provided at the opening.

[0052] Furthermore, the human-computer interaction unit is provided with a device working parameter configuration interface, and the control unit controls the output power of the microwave source according to the working parameters input by the user.

[0053] Furthermore, the human vital signs monitoring unit also includes a weight sensor, and the control unit adjusts the output power of the microwave source according to the weight parameter detected by the weight sensor.

[0054] Furthermore, the human-computer interaction unit includes system operation buttons and a touch display screen.

[0055] Furthermore, the human vital signs sensor includes a breathing sensor, a heart rate sensor, a body temperature sensor, and a blood oxygen sensor.

[0056] The control unit is configured with alarm thresholds and shutdown thresholds for respiratory rate, heart rate, body temperature, and blood oxygen saturation. When any indicator reaches the alarm threshold, the alarm unit is controlled to issue an alarm. When any indicator reaches the shutdown threshold, the microwave source is controlled to stop working.

[0057] Furthermore, the body temperature sensor includes multiple ones, which are respectively arranged at different parts of the human body.

[0058] Beneficial effects of the present invention:

[0059] The whole-body microwave radiation system of the present invention completes the radiation of microwave signals to the human body by designing a wide radiation angle linear antenna array and an innovative cylindrical reflective surface, solving the problem of the existing microwave radiation head having a concentrated radiation range and a fast attenuation of the radiation intensity from the center to the edge within the radiation range, so that microwaves can be radiated relatively evenly to the target heating area. The specially designed array antenna distribution makes the energy generated by microwave electromagnetic radiation more evenly distributed and the temperature rises more steadily, reducing the discomfort of the patient during the thermal therapy. The entire treatment process does not require anesthesia, the patient is fully awake, and the patient can provide timely feedback on the treatment experience, eliminating the side effects of overheating damage, skin burns, pressure sores, etc. caused by the need for general anesthesia in traditional whole-body thermal therapy.

[0060] The heat therapy device of the present invention adopts a specific microwave electromagnetic radiation source, and the power range of the heat source is adjustable, which can be accurately set for different individuals; the system can monitor the vital signs of human breathing, heart rate, blood oxygen saturation, body temperature, etc. in real time. The electromagnetic spectrum with suitable penetration can directly act on the immune organs of the whole body and various diseased parts of the whole body. The equipment can be used to improve the body's immunity, improve blood circulation, and treat cancer patients who are not suitable for radiotherapy, chemotherapy, local hyperthermia, etc. The equipment is fully computer-controlled and operated, and the temperature is fully automatically controlled by the computer. The temperature control accuracy is: ±0. 1°C, which greatly improves the safety of treatment. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] Figure 1 It is a schematic diagram of the principle that microwave antennas are difficult to achieve uniform radiation of the human body.

[0062] Figure 2 It is a schematic diagram of the relationship between the radial cross-section radiation angle of the antenna array used in the whole-body radiation device of the present invention and the target human body area.

[0063] Figure 3 It is a schematic diagram of the radiation principle of the whole body radiation device of the present invention.

[0064] Figure 4 It is a simplified schematic diagram of the structure of the whole body radiation device of the present invention.

[0065] Figure 5 It is a schematic diagram of the antenna array structure of the present invention.

[0066] Figure 6 It is a schematic cross-sectional view of a whole-body radiation device, in which the cross-section of the cylindrical reflecting surface is circular.

[0067] Figure 7 It is a schematic cross-sectional view of a whole-body radiation device, in which the cross-section of the cylindrical reflecting surface is elliptical.

[0068] Figure 8 It is a schematic diagram of a scheme using four antenna arrays.

[0069] Fig. 9 It is a schematic diagram of an improved antenna array structure.

[0070] Fig.10 It is a structural block diagram of the microwave whole body hyperthermia treatment equipment described in the present invention. DETAILED DESCRIPTION

[0071] The technical solution claimed for protection of the present invention is further explained and illustrated below in conjunction with the accompanying drawings.

[0072] Reference Figure 1There are two main reasons why microwave antennas are difficult to achieve uniform heating of the human body. First, the electric field distribution of microwave antennas has the characteristics of high intensity in the center and rapid weakening toward the edge. That is, within the radiation range of the microwave antenna, the radiation intensity of the beam b2 near the edge will be significantly weaker than the radiation intensity of the beam b1 near the 90-degree direction. Therefore, in the area where the human body is irradiated, the parts near the edge heat up slower than the parts near the center, resulting in uneven temperatures in different parts. Second, since the cross-sectional shape of the human body is approximately elliptical, the incident angle θ2 of the beam b2 near the edge of the antenna radiation range radiating to the human body is greater than the incident angle θ1 of the beam b1 near the 90-degree direction. Therefore, the radiation efficiency of the beam b2 near the edge of the antenna radiation range is lower than the radiation efficiency of the beam b1 near the 90-degree direction, which in turn determines that the human body heats up very quickly when radiated toward the front of the antenna, while the parts closer to the sides heat up more slowly when radiated. The above two influencing factors are superimposed on each other, further exacerbating the problem of uneven heating in microwave radiation hyperthermia therapy.

[0073] Example 1

[0074] Reference Figure 2-3 In order to achieve microwave radiation whole-body hyperthermia and avoid local center temperature concentration, the present invention first adopts a patch antenna array arranged along the length of the human body to replace the radiation head used in the existing microwave local hyperthermia equipment, so as to obtain a larger radiation angle, so that the radiation range covers the width of the human body and disperses the microwave energy.

[0075] Then, in order to further achieve relatively uniform heating of the human body by microwave signals, when designing the antenna, the radial cross-sectional radiation angle β of the microwave antenna array is designed to be greater than the angle α corresponding to the target human body area 85. In addition to the beam that is directly irradiated to the human body (shown by the solid line in the figure), the antenna array 56 also reserves a portion of the beam that is not directly irradiated to the human body (shown by the dotted line in the figure). Then, a cylindrical reflecting surface 84 is set around the radiation area, and the reserved portion of the beam is reflected once or multiple times to supplement the part where the direct radiation intensity of the microwave antenna is weaker.

[0076] Reference Figure 4-6 The whole body radiation device is composed of a cylindrical reflective surface 84 and two antenna arrays 56, which are respectively arranged above and below the target human body region 85. The two antenna arrays are parallel to each other and face each other up and down, and the radial cross-sectional radiation angle of the antenna array is greater than the angle corresponding to the target human body region.

[0077] The cylindrical reflective surface is arranged around the radiation area, and microwave shielding structures are arranged at both ends of the cylindrical reflective surface. The shielding structures at both ends and the cylindrical reflective surface together form a closed shielding space, and the two antenna arrays are arranged in the closed shielding space. Figure 4The cross-sectional shape of the cylindrical reflective surface is circular, as shown in FIG. Figure 6 shown.

[0078] The antenna array is formed by 6 antenna units 64 arranged along the length direction. The antenna unit adopts an air-dielectric hybrid microstrip antenna. The antenna is etched on an FR4 printed board with a dielectric constant of 4.4. A metal base plate 63 is used as the ground of the microstrip antenna. The microwave connector is mounted on the metal base plate to facilitate the fixing of the connector. Figure 5 shown.

[0079] Three 1-to-2 power dividers and one 1-to-3 power divider are used to combine the six antenna ports into one total port, and the power dividers are connected by cables. The cables connected to the feed points 87 of each antenna unit are respectively passed through the metal bottom plate 63 to the back and connected to the output end of the 1-to-2 power divider. The input ends of the three 1-to-2 power dividers are respectively connected to the three output ends of the 1-to-3 power divider through cables, and the input end of the 1-to-3 power divider is connected to the microwave source. The metal bottom plate is turned up in the opposite direction of the antenna unit to form a groove structure, and the power dividers and the cables used to connect the power dividers are arranged in the groove structure.

[0080] Reference Figure 7 The cross-sectional schematic diagram of the whole-body radiation device of this example shows that the cross-sectional shape of the cylindrical reflecting surface is an ellipse.

[0081] Reference Figure 8 The microwave whole body radiation device includes four antenna arrays, two of which are respectively arranged above and below the target human body area, and the other two antenna arrays are arranged on both sides of the target human body area. Similarly, the radial cross-sectional radiation angle of each antenna array is greater than the angle corresponding to the target human body area. The supplementary beams of each antenna array reinforce the relatively weak radiation intensity between the two adjacent antenna arrays.

[0082] Reference Fig. 9 In order to allow the antenna array to form a more uniform radiation intensity in the length direction of the human body, the figure illustrates an improved antenna array structure. The antenna array 56 is also a linear microstrip antenna array. The antenna unit 64 that constitutes the antenna array is a patch antenna unit. The antenna unit 64 is a U-shaped structure with an opening direction parallel to the array direction, and the feed point 87 is located at the middle connection point of the U-shaped structure. The U-shaped openings of two adjacent antenna units are in opposite directions. The antenna units that make up a microstrip antenna array are evenly arranged with the center of the C-shaped part of the U-shaped structure as a reference point, and the U-shaped openings of the antenna units at both ends of the antenna array face inward. The two sides of the U-shaped structure are of unequal length, and the long sides and short sides of the two antenna units with opposite openings correspond to each other in an alternating manner.

[0083] Example 2

[0084] Reference Fig.10 The microwave whole body hyperthermia treatment device of the present invention includes a cabin, a control unit, operation buttons respectively connected to the control unit, a touch display screen, an audible and visual alarm, a microwave source, a vital sign signal acquisition module, an operation status signal acquisition module, a bed displacement motor, etc.

[0085] Among them, the operation buttons and touch display screen constitute a human-computer interaction unit, which is used to receive external operation instructions and output relevant information.

[0086] The side wall of the cabin includes a metal layer, and the inner side of the metal layer constitutes a cylindrical reflecting surface. A target human body area is set in the cabin. During heat treatment, the patient lies on a moving bed, and the moving bed brings the patient to the target human body area. An antenna array is set above and below the target human body area, and the two antenna arrays are connected to the output end of the microwave source through feeders. The microwave source is connected to a water cooling device to cool and dissipate the heat for the microwave source to ensure stable operation of the microwave source. The control signal input end of the microwave source is connected to the control unit and is controlled by the control unit. The two antenna arrays, the cylindrical reflecting surface and the microwave source together constitute a microwave radiation system, which is the core part of the equipment. The microwave radiation system used in this embodiment is specifically as described in Example 1, and will not be repeated here.

[0087] The vital sign signal acquisition module is respectively connected to various human vital sign sensors arranged in the cabin, such as a breathing sensor, a heart rate sensor, a body temperature sensor, a blood oxygen sensor, etc. The vital sign signal acquisition module and the various human vital sign sensors arranged in the cabin together constitute a human vital sign monitoring unit, which monitors various human vital sign data in real time and outputs them to the control unit.

[0088] The operation status signal acquisition module is respectively connected to various sensors for monitoring the operation status of the equipment, such as the temperature sensor in the cabin, the bed displacement sensor, etc. The operation status signal acquisition module and the various sensors for monitoring the operation status of the equipment together constitute an equipment operation status monitoring unit, which monitors the operation status data of various equipment in real time and outputs it to the control unit.

[0089] The equipment operation status monitoring unit and the human body vital sign monitoring unit together constitute a complete monitoring system for the equipment.

[0090] When the equipment is running, the control unit receives the operation instruction sent by the human-computer interaction unit and executes the corresponding operation; the control unit is configured with alarm thresholds and shutdown thresholds for respiratory rate, heart rate, body temperature, and blood oxygen saturation. The control unit receives the real-time human vital sign parameters sent by the human vital sign monitoring unit and the real-time equipment operation status sent by the equipment operation status monitoring unit, and selectively sends them to the human-computer interaction unit for external output, while monitoring each human vital sign parameter. When any indicator reaches the alarm threshold, the alarm unit is controlled to issue an alarm, and when any indicator reaches the shutdown threshold, the microwave source is controlled to stop working. In addition, the control unit also adjusts the output power of the microwave source in real time or controls it to stop working according to the monitoring results of the human vital sign monitoring unit, and controls the equipment operation in a preset manner according to the monitoring results of the equipment operation status monitoring unit.

[0091] Experiments have shown that: using the whole-body radiation device of the present invention, operating at a microwave output power of 950W, a 55kg human water model (equivalent to about 80kg human body), the temperature of each part rises by 1.3-1.5℃ every 10 minutes, and after reaching the target temperature, the power is adjusted to 150W to maintain the target temperature.

[0092] The above is an example of the present invention, and is not intended to limit the features of the technical solution of the present invention. Various specific radiation systems or thermal therapy equipment designed based on the concept of the present invention should all fall within the protection scope of the present invention.

Claims

1. A microwave radiation system for microwave whole body hyperthermia, characterized in that: include: A microwave source, used for generating and outputting microwave energy; A whole body radiation device, used to radiate the microwave energy output by the microwave source to the whole body of the target human body; The whole body radiation device comprises a cylindrical reflecting surface, a first antenna array extending along the axial direction of the cylindrical reflecting surface, and a second antenna array extending along the axial direction of the cylindrical reflecting surface, and the microwave source is connected to the first antenna array and the second antenna array respectively; The cylindrical reflecting surface is arranged around the radiation area, and the cylindrical reflecting surface is smooth and has no corners along the circumferential direction; The first antenna array is arranged above the target human body area inside the cylindrical reflecting surface, and the second antenna array is arranged below the target human body area inside the cylindrical reflecting surface; The radiation direction of the first antenna array is downward, the first antenna array is composed of at least one group of directional antenna units, each group of directional antenna units constituting the first antenna array is arranged in a straight line along the axial direction of the cylindrical reflective surface, the radiation directions of the directional antenna units are the same, and the radial cross-section radiation angle of the first antenna array is greater than the angle corresponding to the target human body area; The second antenna array radiates upward, the second antenna array is composed of at least one group of directional antenna units, each group of directional antenna units constituting the second antenna array is arranged in a straight line along the axial direction of the cylindrical reflective surface, the radiation directions of the directional antenna units are the same, and the radial cross-section radiation angle of the second antenna array is greater than the angle corresponding to the target human body area; The antenna array is a linear microstrip antenna array. The antenna units that make up the antenna array are patch antenna units. The antenna units are U-shaped structures with their opening direction parallel to the array direction. The feed point is located at the middle connection point of the U-shaped structure. The U-shaped opening directions of two adjacent antenna units are opposite. The antenna units that make up a microstrip antenna array are evenly arranged with the center of the C-shaped part in the U-shaped structure as a reference point. The U-shaped openings of the antenna units at both ends of the antenna array face inward. The two sides of the U-shaped structure are of unequal lengths, and the long sides and short sides of the two antenna units with opposite openings correspond alternately.

2. The microwave radiation system according to claim 1, characterized in that: The whole body radiation device also includes an antenna array arranged on the side of the target human body area.

3. The microwave radiation system according to claim 1, characterized in that: The first antenna array and the second antenna array are parallel to each other and aligned vertically.

4. The microwave radiation system according to claim 1, characterized in that: Microwave shielding structures are arranged at both ends of the cylindrical reflecting surface, and the shielding structures at both ends and the cylindrical reflecting surface together form a closed shielding space.

5. The microwave radiation system according to claim 1, characterized in that: The radiation area is formed in a cabin, the side wall of the cabin includes an inner shielding layer and an outer shell, and the cylindrical reflection surface is formed on the inner side of the inner shielding layer of the cabin.

6. The microwave radiation system according to claim 5, characterized in that: The two ends of the cabin body are provided with microwave shielding end plates, and the microwave shielding end plates at the two ends of the cabin body are sealed and connected with the inner shielding layer of the cabin body side wall to form the inner shielding body of the cabin body.

7. The microwave radiation system according to claim 6, characterized in that: An opening for people to enter and exit the cabin is arranged on a microwave shielding end plate at one end of the cabin, and a shielding curtain is arranged at the opening.

8. A microwave whole body hyperthermia device, characterized in that: It comprises a control unit, a human-computer interaction unit, an alarm unit, a microwave radiation system according to any one of claims 1 to 7, and a monitoring system; The human-computer interaction unit is used to accept operation instructions and output relevant information; The monitoring system includes a human vital signs monitoring unit and an equipment operation status monitoring unit; The human vital sign monitoring unit includes a vital sign signal acquisition module and a group of human vital sign sensors respectively connected to the vital sign signal acquisition module, the vital sign signal acquisition module respectively acquires signals from each human vital sign sensor and outputs them to the control unit; The equipment operation status monitoring unit includes an operation status signal acquisition module and a group of operation status sensors respectively connected to the operation status signal acquisition module, and the operation status signal acquisition module respectively acquires signals from each operation status sensor and outputs them to the control unit; The control unit receives the instruction sent by the human-computer interaction unit and executes the corresponding control function according to the instruction; The control unit receives the real-time human vital sign parameters sent by the human vital sign monitoring unit and the real-time equipment operation status sent by the equipment operation status monitoring unit, and selectively sends them to the human-computer interaction unit for external output, while monitoring each human vital sign parameter. When a human vital sign parameter exceeds a preset threshold value, the alarm unit is controlled to alarm externally; The control unit adjusts the output power of the microwave source in real time or controls it to stop working according to the monitoring result of the human vital sign monitoring unit; The control unit controls the operation of the equipment in a preset manner according to the monitoring result of the equipment operation status monitoring unit.

9. The microwave whole body hyperthermia treatment device according to claim 8, characterized in that: The human-computer interaction unit is provided with an equipment working parameter configuration interface, and the control unit controls the output power of the microwave source according to the working parameters input by the user; The human body vital signs monitoring unit also includes a weight sensor, and the control unit adjusts the output power of the microwave source according to the weight parameter detected by the weight sensor; The human-computer interaction unit includes system operation buttons and a touch display screen.

10. The microwave whole body hyperthermia treatment device according to claim 8, characterized in that: The human body vital signs sensor includes a breathing sensor, a heart rate sensor, a body temperature sensor, and a blood oxygen sensor; The control unit is configured with alarm thresholds and shutdown thresholds for respiratory rate, heart rate, body temperature, and blood oxygen saturation. When any indicator reaches the alarm threshold, the alarm unit is controlled to issue an alarm. When any indicator reaches the shutdown threshold, the microwave source is controlled to stop working.

11. The microwave whole body hyperthermia treatment device according to claim 10, characterized in that: The body temperature sensors include a plurality of body temperature sensors, which are respectively arranged at different parts of the human body.

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