An embedding device for preventing leakage of small tissues in pathological biopsy

By designing an embedding device with an inner frame and accommodating frame, the problem of biopsy tissue leakage when the embedding box is large and the pore diameter is incompletely dehydrated when the embedding box is small, achieving the dual goal of effectively preventing spills and ensuring the dehydration treatment effect.

CN115014919BActive Publication Date: 2025-04-01SICHUAN KINGMED DIAGNOSTICS CENT
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Patent Information

Application Number
CN202210779540.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2022-07-04
Publication Date
2025-04-01
Estimated Expiration
2042-07-04

AI Technical Summary

Technical Problem

The existing embedding box has large pore size and is prone to leaking in small biopsies, and the dehydration treatment is incomplete when the pore size is small.

Method used

An embedding device is designed, including a box body, an inner frame and a receiving frame. A first leak hole structure with a larger aperture is provided on the box body, a second leak hole structure with a smaller aperture is provided on the receiving frame, and a structure supporting the receiving frame is provided on the inner frame to ensure that the receiving frame can effectively prevent biopsy tissue from leaking, and to ensure that the dehydration treatment liquid can fully enter.

Benefits of technology

Effectively prevent small tissue spills in biopsy, while ensuring the integrity of the dehydration treatment, ensuring that the treatment liquid can fully enter the embedded box, and even if the box is stacked and placed, it will not affect the dehydration effect.

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Abstract

The present invention belongs to a tissue sample embedding device, and specifically discloses an embedding device for preventing small tissues from leaking during pathological biopsy, comprising a box body, on which a plurality of first leak hole structures are arranged, an inner frame is arranged in the box body, on which a plurality of receiving frames for accommodating tissue samples are arranged, at least one of the receiving frames is provided with a second leak hole structure, and the aperture of the second leak hole structure is smaller than that of the first leak hole structure. The embedding device of the present invention can ensure the effect of dehydration treatment, and can effectively avoid the problem of small tissue leaking.
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Description

Technical Field

[0001] The invention relates to the technical field of sample storage devices, and in particular to an embedding device for preventing leakage of small tissues in pathological biopsy. Background Art

[0002] The embedding box is used for dehydration and wax dipping of tissue samples, and then placed on a cooling table to be shaped by cooling, which facilitates subsequent sectioning to prepare sections for inspection.

[0003] However, the existing embedding cassettes generally have large apertures, and small biopsy tissues with small volumes are easily leaked out of the embedding cassettes. If the aperture is set smaller, although the small biopsy tissues are not easy to leak out, the aperture is small, and when the embedding cassettes are dehydrated, the cassette bodies are generally stacked and placed, and the aperture is easily blocked, resulting in the processing liquid being able to fill the interior of the cassette body, resulting in poor dehydration effect. Summary of the invention

[0004] The purpose of the present invention is to solve the problem in the prior art that biopsy tissue is easy to leak out when the aperture of the embedding box is large and the dehydration treatment is incomplete when the aperture is small, and to provide an embedding device that prevents leakage of small tissues of pathological biopsy and ensures effective dehydration treatment.

[0005] The present invention is achieved through the following technical solutions:

[0006] A device for preventing leakage of small tissues in pathological biopsy, comprising a box body, on which a plurality of first leakage hole structures are arranged, an inner frame is arranged in the box body, on which a plurality of accommodating frames for accommodating tissue samples are arranged, at least one of the accommodating frames is provided with a second leakage hole structure, and the aperture of the second leakage hole structure is smaller than the aperture of the first leakage hole structure.

[0007] Optionally, the cross section of the containing frame adopts an incomplete circular structure, the box body is connected to a box cover, and the box cover is provided with a frame cover plate capable of covering the containing frame.

[0008] Optionally, the accommodating frame is connected to the inner frame by a rotating structure, and a reset torsion spring capable of resetting the accommodating frame is provided in the rotating structure.

[0009] Optionally, an embedding mold is further included, wherein the embedding mold is provided with a first supporting portion for supporting the inner frame, and when the inner frame is supported on the first supporting portion, the bottom of the accommodating frame can be immersed in the cavity of the embedding mold.

[0010] Optionally, a second supporting portion for supporting the accommodating frame is provided on the inner frame, and the second supporting portion can be embedded in the first supporting portion to form a supporting position.

[0011] Optionally, the distance between every two first support parts is equal to the distance between every two second support parts, so that the second support parts can be staggered with the first support parts, thereby ensuring that each accommodating frame can be located in the cavity of the embedding mold.

[0012] Optionally, a rotating handle is provided at the end of the accommodating frame.

[0013] The technical solution of the present invention has at least the following beneficial effects:

[0014] The device for preventing leakage of small tissues from pathological biopsies of the present invention can embed the accommodating frame for accommodating biopsy tissues into the box body by arranging an inner frame and a accommodating frame in the box body. Meanwhile, the box body has a relatively large aperture structure to ensure that the dehydration treatment liquid can be immersed in the box body. Even if the box bodies are stacked, the dehydration treatment liquid will not be unable to enter the box body. The accommodating frame adopts a small aperture structure to effectively prevent the biopsy tissues from leaking out. Meanwhile, the box body serves as a basic support, and the small aperture accommodating frame will not have the problem of incomplete liquid filling due to the problem of stacking. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a front cross-sectional view of the embedding device of the present invention;

[0016] Figure 2 It is a front view of the inner frame and the containing frame of the present invention;

[0017] Figure 3 It is a front view of the embedding mold of the present invention;

[0018] Figure 4 This is a front view of the embedding mold and the inner frame and other supporting structures of the present invention;

[0019] Figure 5 It is a cross-sectional view of the matching state of the embedding mold and the inner frame part of the present invention.

[0020] Icon: 110 - box body, 120 - box cover, 101 - first leakage hole structure, 210 - inner frame, 220 - containing frame, 230 - second supporting part, 240 - rotating handle, 250 - frame cover, 201 - second leakage hole structure, 300 - embedding mold, 301 - first supporting part. DETAILED DESCRIPTION

[0021] Reference Figure 1-5The present invention provides an embedding device for preventing leakage of pathological biopsy small tissues, including an embedding box, the embedding box including a box body 110 and a box cover 120, the box body 110 and the box cover 120 are both provided with a plurality of first leakage hole structures 101, the box body 110 is provided with an inner frame 210, the inner frame 210 is provided with a plurality of receiving frames 220 for receiving tissue samples, at least one receiving frame 220 is provided with a second leakage hole structure 201, and the aperture of the second leakage hole structure 201 is smaller than the aperture of the first leakage hole structure 101. The inner frame 210 is installed in the box body 110 in a removable manner, and when dehydration treatment is performed, the biopsy tissue can be placed in the receiving frame 220, and then the box cover 120 is closed, and the entire embedding box can be placed in the dehydration treatment device and immersed in the dehydration treatment liquid. In this embodiment, the aperture of the second leakage hole structure 201 is smaller than the aperture of the first leakage hole structure 101, and the specific size can be arranged according to the size of the general biopsy small tissue that is not easy to leak out. Since the box body 110 has a relatively large aperture structure, it is ensured that the dehydration treatment liquid can be immersed in the box body 110. Even if the box bodies 110 are stacked, it will not cause the problem that the dehydration treatment liquid cannot enter the box body 110. The receiving frame 220 adopts a small aperture structure, which can effectively prevent the biopsy tissue from leaking out. At the same time, the box body 110 serves as a basic support, and the small aperture receiving frame 220 will not have the problem of incomplete liquid filling due to the problem of stacking.

[0022] In order to ensure a better liquid inlet effect, the cross section of the receiving frame 220 adopts an incomplete circular structure, and the box cover 120 of the box body 110 is provided with a frame cover plate 250 that can cover the receiving frame 220. By setting the receiving frame 220 structure with a circular cross section, there is a larger space for storing liquid between the receiving frame 220 and the receiving frame 220, and between the receiving frame 220 and the inner wall of the box body 110, which can ensure that the liquid can smoothly enter the receiving frame 220 after entering the box body 110, so as to ensure a better dehydration treatment effect. After the frame cover plate 250 cooperates with the receiving frame 220, a complete circular cavity can be formed, ensuring that the biopsy tissue will not fall out of the receiving frame 220 after the box cover 120 is closed. At the same time, in order to ensure that the frame cover 250 can fit closely with the containing frame 220, the connection angle between the frame cover 250 and the box cover 120 needs to be appropriately adjusted according to the position of different containing frames 220. At the same time, the frame cover 250, the box cover 120 and the containing frame 220 are all plastic parts with a certain deformation amount, so after being buckled together, a good sealing effect can also be guaranteed.

[0023] The receiving frame 220 is connected to the inner frame 210 by a rotating structure, and a reset torsion spring (not shown) is provided in the rotating structure to reset the receiving frame 220. Specifically, both ends of the receiving frame 220 are installed on the inner frame 210 through a rotating shaft. In order to facilitate the rotation of the receiving frame 220, a rotating handle 240 is provided at one end to conveniently rotate the receiving frame 220. The connecting position of the rotating shaft of the receiving frame 220 and the inner frame 210 is also provided with a reset torsion spring, so that the receiving frame 220 can quickly return to the initial state after being released. In this way, when the biopsy tissue in the receiving frame 220 is subsequently transferred, it can be conveniently poured into the embedding mold 300.

[0024] The embedding device further comprises an embedding mold 300, which is provided with a first support portion 301 for supporting the inner frame 210. When the inner frame 210 is supported on the first support portion 301, the bottom of the receiving frame 220 can be immersed in the concave cavity of the embedding mold 300. After the embedding box is connected to the biopsy tissue and dehydrated in the dehydration device, the embedding mold 300 is also pre-placed in the wax liquid, and then the mold can be taken out from the wax liquid, the middle concave cavity is filled with wax liquid with a certain temperature, the embedding box after dehydration is taken out, and then the box cover 120 is opened, the inner frame 210 can be taken out, and then placed on the embedding mold 300, so that the bottom of the receiving frame 220 can just be immersed in the wax liquid of the embedding mold 300. When the receiving frame is rotated, the biopsy tissue can be easily poured into the middle concave cavity. If it is not immersed in the wax liquid, the biopsy tissue is attached to the receiving frame 220 and is difficult to pour down. At the same time, the time the biopsy component in the embedding box is extracted from the dehydrating agent and transferred to the wax liquid in the embedding mold 300 is significantly reduced, which can greatly reduce the possibility of contamination of the biopsy tissue. On the other hand, the biopsy tissue is directly poured from the containing frame 220 into the wax liquid in the embedding mold 300 without the need for other tools (such as tweezers) to grasp it, which also reduces the impact of other tools on the biopsy tissue due to inadequate cleaning during manual operation.

[0025] Further, the inner frame 210 is provided with a second support portion 230 for supporting the accommodating frame 220, and the second support portion 230 can be embedded in the first support portion 301 to form a support position. In this way, the inner frame 210 and the embedding mold 300 can be positioned, so that the accommodating frame 220 can be located above the concave cavity, and the biopsy tissue can fall into the concave cavity when it is poured out. In this embodiment, in order to increase the biopsy tissue accommodating capacity of the embedding box, the accommodating frame 220 is generally provided with more groups. In this embodiment, 3 groups are provided, and of course more groups can be provided as needed. For the case of 3 groups, the second support portion 230 and the first support portion 301 of the embodiment are both provided with 3, and the spacing between every two first support portions 301 is equal to the spacing between every two second support portions 230, so that the second support portion 230 can be staggered with the first support portion 301, thereby ensuring that each accommodating frame 220 can be located in the concave cavity of the embedding mold 300. In this way, the middle receiving frame 220 can be ensured to be facing the concave cavity in the state shown in the figure. If the left receiving frame 220 is to be tilted, the inner frame 210 can be moved to the right to release the biopsy tissue in the left receiving frame 220. In order to ensure that the receiving frame 220 can be immersed in the wax liquid at any position, the liquid-containing part of the embedding mold 300 should be designed to be large enough. Those skilled in the art can make adjustments according to the method shown in the figure to ensure that the receiving frame 220 can be immersed in the liquid when the inner frame 210 moves left and right.

Claims

1. A device for preventing leakage of small tissues in pathological biopsy, comprising a box body, on which a plurality of first leakage hole structures are arranged, characterized in that: The box body is provided with an inner frame, and the inner frame is provided with a plurality of accommodating frames for accommodating tissue samples, at least one of the accommodating frames is provided with a second leak hole structure, and the aperture of the second leak hole structure is smaller than the aperture of the first leak hole structure; The cross section of the containing frame adopts an incomplete circular structure, the box body is connected to a box cover, and the box cover is provided with a frame cover plate that can cover the containing frame; The containing frame is connected to the inner frame by a rotating structure, and a reset torsion spring capable of resetting the containing frame is arranged in the rotating structure; It also includes an embedding mold, which is provided with a first supporting portion for supporting the inner frame. When the inner frame is supported on the first supporting portion, the bottom of the accommodating frame can be immersed in the cavity of the embedding mold.

2. The device for preventing leakage of small tissues from pathological biopsy according to claim 1, characterized in that: The inner frame is provided with a second supporting portion for supporting the accommodating frame, and the second supporting portion can be embedded in the first supporting portion to form a supporting position.

3. The device for preventing leakage of small tissues from pathological biopsy according to claim 2, characterized in that: The distance between every two first supporting parts is equal to the distance between every two second supporting parts, so that the second supporting parts can be staggered with the first supporting parts, thereby ensuring that each accommodating frame can be located in the cavity of the embedding mold.

4. The device for preventing leakage of small tissues from pathological biopsy according to any one of claims 1 to 3, characterized in that: A rotating handle is arranged at the end of the accommodating frame.

Citation Information

Patent Citations

  • Live body dehydrating tissue box and place embedded box of live body dehydrating tissue box

    CN208313678U