A pipeline fully sealed pressure monitoring device

Abstract

The present invention provides a pipeline fully sealed pressure monitoring device, comprising: a mounting substrate, a fluid channel, a sensor and a pressure plate; the fluid channel and the sensor are arranged between the mounting substrate and the pressure plate, the fluid channel comprises a flexible elastic membrane, when the internal pressure of the fluid channel changes, the fluid channel is constrained by the mounting substrate and the pressure plate, and the flexible elastic membrane generates deformation, the sensor detects the pressure or displacement, and outputs the internal pressure value of the fluid channel. The pipeline fully sealed pressure monitoring device provided by the present invention detects the pressure or displacement generated by the deformation of the fluid channel in the sealed pipeline state by setting a resistance strain gauge sensor or a displacement deformation sensor; the hydrophobic filter membrane is eliminated to realize a truly fully sealed pipeline channel, avoid air pollution from the source, and improve the safety of the pipeline system; the structure is simple, the cost is low, the detection accuracy is high, and it is easy to use.

Description

Technical Field

[0001] The invention relates to the technical field of biological cell processing, and in particular to a pipeline fully sealed pressure monitoring device. Background Art

[0002] At present, when performing cell preparation or single blood collection, the air-permeable and water-impermeable hydrophobic filter membrane is commonly used for pipeline or system pressure monitoring. The pressure of the liquid in the pipeline is transmitted to the pressure sensor through the air that can pass through the hydrophobic filter membrane. That is, there is usually pressurized air on both sides of the hydrophobic filter membrane to achieve pressure monitoring. However, this method has the following problems:

[0003] 1. In order to achieve gas pressure transmission, it is necessary to ensure the airtightness of the connection between the pipeline and the pressure sensor. At present, Luer sealing joints are usually used. The connection parts between the pressure sensor end and the Luer joint need to be precisely processed with a taper to achieve hard contact airtightness. During installation, it is necessary to ensure that the knob is in place, but not to use too much force to break the Luer joint and affect the airtightness. The cost is high and the operation is inconvenient.

[0004] 2. Ensure the permeability of the hydrophobic filter membrane to achieve pressure monitoring. In actual use, abnormal pressure changes are often encountered, and liquids, especially high-concentration blood or cell fluids, come into contact with the hydrophobic filter membrane, causing the hydrophobic filter membrane to be blocked, resulting in the pressure sensor being unable to sense the pressure of the pipeline or system to be tested.

[0005] 3. There are certain safety risks. Generally, the diameter of bacteria is about 0.5-5um. Although the cell culture preparation industry generally adopts 0.2um hydrophobic filter membrane, first of all, in terms of design principle, it has not achieved true full sealing. Secondly, the hydrophobic filter membrane has a damage or qualification rate, and the possibility of bacteria mixing is relatively high, which has a greater safety impact on relatively fragile cells. Summary of the invention

[0006] In order to solve at least one of the above technical problems, the technical solution adopted by the present invention is to provide a pipeline fully sealed pressure monitoring device. The pipeline fully sealed pressure monitoring device provided by the present invention has a simple structure, low cost, high detection accuracy, and is easy to use and highly safe.

[0007] The technical solution provided by the present invention is:

[0008] The present invention provides a pipeline fully sealed pressure monitoring device, comprising: a mounting substrate, a fluid channel, a sensor and a pressure plate; the fluid channel and the sensor are arranged between the mounting substrate and the pressure plate, the fluid channel comprises a flexible elastic membrane, when the internal pressure of the fluid channel changes, the fluid channel is constrained by the mounting substrate and the pressure plate, and the flexible elastic membrane generates deformation, the sensor detects the pressure or displacement, and outputs the internal pressure value of the fluid channel.

[0009] Further, when the sensor detects the pressure, the sensor is a resistance strain gauge sensor.

[0010] Furthermore, the resistance strain gauge sensor is arranged on a mounting substrate, and the fluid channel is connected to the resistance strain gauge sensor by pressure conduction through a first contact surface; and the pressure plate is a fixed pressure plate.

[0011] Furthermore, the first contact surface is fixedly connected to the fluid channel or the first contact surface is fixedly connected to the resistance strain gauge sensor.

[0012] Furthermore, when the fluid channel is in a zero-pressure state, the flexible elastic membrane is in a compressed state, and the resistance strain gauge sensor is subjected to a preset pressure of the fluid channel; the internal negative pressure measurement of the fluid channel is achieved by the preset pressure.

[0013] Furthermore, when there is positive pressure in the fluid channel, the fluid channel expands toward the resistance strain gauge sensor, and the pressure sensing value of the resistance strain gauge sensor increases; when there is negative pressure in the fluid channel, the preset pressure decreases, and the pressure sensing value of the resistance strain gauge sensor decreases.

[0014] Furthermore, a contact surface locking device is fixedly connected between the fluid channel and the first contact surface; the contact surface locking device connects the fluid channel and the resistance strain gauge sensor for pressure conduction.

[0015] Furthermore, the fluid channel is fixedly connected to the fixed pressure plate; when there is negative pressure in the fluid channel, the fluid channel generates an upward pulling force on the resistance strain gauge sensor through the contact surface locking device and the first contact surface, thereby measuring the negative pressure in the fluid channel; when there is positive pressure in the fluid channel, the fluid channel generates a downward pressure on the resistance strain gauge sensor through the contact surface locking device and the first contact surface, thereby measuring the positive pressure in the fluid channel.

[0016] Further, when the sensor detects the displacement, the sensor is a displacement deformation sensor.

[0017] Furthermore, the pressure plate is a movable pressure plate; the displacement deformation sensor is connected to the movable pressure plate through a fixed locking device; the fluid channel is fixedly connected to the movable pressure plate; when there is negative pressure in the fluid channel, the fluid channel drives the movable pressure plate to move toward the mounting substrate, causing the displacement deformation sensor to generate displacement deformation, thereby measuring the negative pressure in the fluid channel; when there is positive pressure in the fluid channel, the fluid channel drives the movable pressure plate to move away from the mounting substrate, causing the displacement deformation sensor to generate displacement deformation, thereby measuring the positive pressure in the fluid channel.

[0018] Compared with the prior art, the pipeline fully sealed pressure monitoring device provided by the present invention has the following beneficial effects:

[0019] The present invention detects the pressure or displacement generated by the deformation of the fluid channel in a sealed pipeline state by setting a resistance strain gauge sensor or a displacement deformation sensor, and realizes the positive and negative pressure detection in the fluid channel outside the fluid channel; the hydrophobic filter membrane is eliminated to realize a truly fully sealed pipeline channel, avoid air pollution from the source, and improve the safety of the pipeline system; at the same time, the Luer connector is eliminated, and the risk of air leakage caused by the mismatch between the Luer connector and the equipment or improper installation operation due to processing is completely avoided, and the equipment processing accuracy requirements are reduced.

[0020] It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not intended to limit the scope of protection of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of a fluid channel in a fully sealed pipeline pressure monitoring device in a natural state without being squeezed in the first embodiment of the present invention;

[0022] Figure 2 This is a schematic diagram of the structure of the fully sealed pipeline pressure monitoring device during measurement in the first embodiment of the present invention;

[0023] Figure 3 It is a schematic diagram of the force model of the pipeline fully sealed pressure monitoring device in the first embodiment of the present invention;

[0024] Figure 4 This is a schematic diagram of the structure of a fully sealed pipeline pressure monitoring device in Embodiment 2 of the present invention;

[0025] Figure 5 This is a schematic diagram of the structure of a fully sealed pipeline pressure monitoring device in Embodiment 3 of the present invention;

[0026] Among them, 1 is a mounting substrate, 2 is a resistance strain gauge sensor, 3 is a contact surface, 4 is a fluid channel, 5 is a flexible elastic membrane, 6 is a fixed pressure plate, 7 is a contact surface locking device, 8 is a displacement deformation sensor, 9 is a fixed locking device, and 10 is a movable pressure plate. DETAILED DESCRIPTION

[0027] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention is further described in detail below in conjunction with specific embodiments. Please note that the embodiments described below are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention. If no specific technology or conditions are specified in the embodiments, the technology or conditions described in the literature in the art or the product instructions shall be followed.

[0028] In the description of the present invention, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0029] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0030] The fully sealed pipeline pressure monitoring device provided by the present invention will be described in detail below through specific embodiments:

[0031] Embodiment 1

[0032] like Figure 1-2 As shown, the fully sealed pipeline pressure monitoring device provided in this embodiment includes components such as a mounting substrate 1, a resistance strain gauge sensor 2, a contact surface 3, a fluid channel 4, a flexible elastic membrane 5 and a fixed pressure plate 6.

[0033] The resistance strain gauge sensor 2 is fixed on the mounting substrate 1, and the resistance strain gauge sensor 2 is connected to the fluid channel 4 by pressure conduction through the contact surface 3. Further, the contact surface 3 can be fixedly connected to the fluid channel 4, and the contact surface 3 can also be fixedly connected to the resistance strain gauge sensor 2. The fluid channel 4 includes a flexible elastic membrane 5, and when the pressure in the fluid channel 4 changes, a certain deformation can be generated through the flexible elastic membrane 5.

[0034] The fixed pressure plate 6 is fixedly arranged on the side of the fluid channel 4 opposite to the resistance strain gauge type sensor 2 , that is, the fluid channel 4 is arranged between the resistance strain gauge type sensor 2 and the fixed pressure plate 6 .

[0035] The force model of the fully sealed pipeline pressure monitoring device provided by the present invention is as follows: Figure 3 As shown. In the ideal case where the deformation and force change of the flexible elastic membrane 5 are not considered, Figure 1 The fluid channel 4 shown is in a natural state without being squeezed, that is, in a zero pressure state, the flexible elastic membrane 5 on the fluid channel 4 is in a certain compression state, and the resistance strain gauge sensor 2 is in a certain stress state. At this time, the pressure on the resistance strain gauge sensor 2 is aN, that is, the fluid channel 4 generates a preset pressure on the resistance strain gauge sensor 2. The area of ​​the contact surface 3, that is, the contact area between the fluid volume channel 4 and the resistance strain gauge sensor 2 is b cm 2 The pressure value in the fluid pipeline 4 is x, and x can be a positive value or a negative value; the pressure value that can be measured by the resistance strain gauge sensor 2 is y=a+x.

[0036] When the fluid channel 4 is under positive pressure, the fluid channel 4 expands toward the resistance strain gauge sensor 2 due to the fixed pressure plate 6 and the deformation of the flexible elastic film 5. The force on the resistance strain gauge sensor 2 increases, and the pressure sensing value output by the resistance strain gauge sensor 2 increases. Therefore, when the fluid channel 4 is under positive pressure, the resistance strain gauge sensor 2 can measure the pressure value y=a+|x|, and the pressure value in the fluid channel 4 is

[0037] When the fluid channel 4 is under negative pressure, the preset pressure generated by the fluid channel 4 on the resistance strain gauge sensor 2 is reduced due to the fixed pressure plate 6 and the deformation of the flexible elastic membrane 5, the force on the resistance strain gauge sensor 2 is reduced, and the pressure sensing value output by the resistance strain gauge sensor 2 is reduced until it reaches 0; therefore, when the fluid channel 4 is under negative pressure, the minimum pressure that can be measured by the resistance strain gauge sensor 2 is y=a-|x|, and y is 0 at the minimum, so the maximum negative pressure that can be measured in the fluid channel 4 is x=-a; since the fluid channel 4 has a preset pressure on the resistance strain gauge sensor 2, the negative pressure can be measured according to the preset pressure. Therefore, according to the preset pressure and the measured pressure of the resistance strain gauge sensor 2, the pressure value in the fluid channel 4 is

[0038] Embodiment 2

[0039] The pipeline fully sealed pressure monitoring device provided in this embodiment will be specifically introduced in terms of its differences from the first embodiment, and the similarities will not be repeated in this embodiment.

[0040] In this embodiment, the fluid channel 4 does not provide a preset pressure to the resistance strain gauge sensor 2, but a contact surface locking device 7 is added between the fluid channel 4 and the contact surface 3. The contact surface locking device 7 connects the fluid channel 4 with the contact surface 3, and further connects the fluid channel 4 with the resistance strain gauge sensor 2 for pressure conduction; and the fluid channel 4 is connected to the fixed pressure plate 6.

[0041] When the fluid channel 4 is under negative pressure, the fluid channel 4 can generate an upward pulling force on the resistance strain gauge sensor 2 through the contact surface locking device 7 and the contact surface 3, thereby realizing the measurement of the negative pressure in the fluid channel 4. When the fluid channel 4 is under positive pressure, the fluid channel 4 can generate a downward pressure on the resistance strain gauge sensor 2 through the contact surface locking device 7 and the contact surface 3, thereby realizing the measurement of the positive pressure in the fluid channel 4. Compared with the first embodiment, this embodiment is more convenient to install.

[0042] Embodiment 3

[0043] The pipeline fully sealed pressure monitoring device provided in this embodiment will be specifically introduced in terms of its differences from the first embodiment, and the similarities will not be repeated in this embodiment.

[0044] In this embodiment, the resistance strain gauge sensor 2 is no longer arranged between the mounting substrate 1 and the contact surface 3, that is, the mounting substrate 1 is in direct contact with the contact surface 3. The fixed pressing plate 6 is replaced by a movable pressing plate 10, and a displacement deformation sensor 8 is arranged between the movable pressing plate 10 and the mounting substrate 1. The displacement deformation sensor 8 is connected to the movable pressing plate 10 through a fixing and locking device 9. At the same time, the fluid channel 4 is fixedly connected to the movable pressing plate 10.

[0045] When the fluid channel 4 is under negative pressure, the fluid channel 4 drives the movable pressure plate 10 to move toward the mounting substrate 1, causing the displacement deformation sensor 8 to generate displacement deformation, thereby realizing the measurement of the negative pressure in the fluid channel 4. When the fluid channel 4 is under positive pressure, the fluid channel 4 drives the movable pressure plate 10 to move away from the mounting substrate 1, causing the displacement deformation sensor 8 to generate displacement deformation, thereby realizing the measurement of the positive pressure in the fluid channel 4.

[0046] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0047] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

Claims

1. A pipeline fully sealed pressure monitoring device, characterized in that: include: A mounting substrate, a fluid channel, a sensor and a pressure plate; the fluid channel and the sensor are arranged between the mounting substrate and the pressure plate, the fluid channel includes a flexible elastic membrane, when the internal pressure of the fluid channel changes, the fluid channel is constrained by the mounting substrate and the pressure plate, and the flexible elastic membrane is deformed, and the sensor detects the pressure or displacement and outputs the internal pressure value of the fluid channel; when the sensor detects the pressure, the sensor is a resistance strain gauge sensor; the resistance strain gauge sensor is arranged on the mounting substrate, and the fluid channel is connected to the resistance strain gauge sensor through a first contact surface for pressure conduction; the pressure plate is a fixed pressure plate; the first contact surface is fixedly connected to the fluid channel or the first contact surface is fixedly connected to the resistance strain gauge sensor; when the fluid channel is in a zero-pressure state, the flexible elastic membrane is in a compressed state, and the resistance strain gauge sensor is subjected to a preset pressure of the fluid channel; the internal negative pressure measurement of the fluid channel is achieved by the preset pressure.

2. The pipeline fully sealed pressure monitoring device according to claim 1, characterized in that: When there is positive pressure in the fluid channel, the fluid channel expands toward the resistance strain gauge sensor, and the pressure sensing value of the resistance strain gauge sensor increases; when there is negative pressure in the fluid channel, the preset pressure decreases, and the pressure sensing value of the resistance strain gauge sensor decreases.

3. A pipeline fully sealed pressure monitoring device, characterized in that: include: The mounting substrate includes a fluid channel, a sensor and a pressure plate; the fluid channel and the sensor are arranged between the mounting substrate and the pressure plate, the fluid channel includes a flexible elastic membrane, when the internal pressure of the fluid channel changes, the fluid channel is constrained by the mounting substrate and the pressure plate, and deforms through the flexible elastic membrane, the sensor detects the pressure or displacement, and outputs the internal pressure value of the fluid channel; when the sensor detects the pressure, the sensor is a resistance strain gauge sensor; the resistance strain gauge sensor is arranged on the mounting substrate, and the fluid channel is connected to the resistance strain gauge sensor through a first contact surface for pressure conduction; the pressure plate is a fixed pressure Plate; a contact surface locking device is fixedly connected between the fluid channel and the first contact surface; the contact surface locking device fixes the fluid channel and the resistance strain gauge type sensor for pressure conduction; the fluid channel is fixedly connected to the fixed pressure plate; when the fluid channel is under negative pressure, the fluid channel generates an upward pulling force on the resistance strain gauge type sensor through the contact surface locking device and the first contact surface, thereby measuring the negative pressure in the fluid channel; when the fluid channel is under positive pressure, the fluid channel generates a downward pressure on the resistance strain gauge type sensor through the contact surface locking device and the first contact surface, thereby measuring the positive pressure in the fluid channel.

4. A pipeline fully sealed pressure monitoring device, characterized in that: include: A mounting substrate, a fluid channel, a sensor and a pressure plate; the fluid channel and the sensor are arranged between the mounting substrate and the pressure plate, the fluid channel includes a flexible elastic membrane, when the internal pressure of the fluid channel changes, the fluid channel is constrained by the mounting substrate and the pressure plate, and deforms through the flexible elastic membrane, the sensor detects the pressure or displacement, and outputs the internal pressure value of the fluid channel; when the sensor detects the displacement, the sensor is a displacement deformation sensor; The pressure plate is a movable pressure plate; the displacement deformation sensor is connected to the movable pressure plate through a fixed locking device; the fluid channel is fixedly connected to the movable pressure plate; when the fluid channel is under negative pressure, the fluid channel drives the movable pressure plate to move toward the mounting substrate, causing the displacement deformation sensor to generate displacement deformation, thereby measuring the negative pressure in the fluid channel; when the fluid channel is under positive pressure, the fluid channel drives the movable pressure plate to move away from the mounting substrate, causing the displacement deformation sensor to generate displacement deformation, thereby measuring the positive pressure in the fluid channel.

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