Sample processing device, sample analyzer, and sample processing method

Abstract

The present application relates to a kind of sample processing device, sample analyzer and sample processing method, sample processing device includes stem component and control part.Stem component is used to extend into the sample container for containing sample carrier component and diluent, sample carrier component is adhered with sample, diluent is used to dilute the sample.Control part is used to control the stem component along the center area of the sample container extends into the sample container, then control the stem component moves to the direction close to the side wall of the sample container, again control the stem component moves to the bottom of the sample container.When stem component is in the sample container, stem component moves to the inside of the sample container, after avoiding the center area of the sample container, again moves along the direction close to the bottom of the sample container, so that the end of stem component can avoid the center of the bottom of the sample container when moving to the bottom of the sample container, prevent stem component from inserting sample carrier component.

Description

Technical Field

[0001] This invention relates to the field of detection technology, and in particular to a sample processing device, a sample analyzer, and a sample processing method. Background Technology

[0002] In the detection and analysis process, automated operating mechanisms are often used to insert rod-shaped components into sample containers to process the sample solution. However, sample containers may contain sample carriers such as cotton swabs or cotton balls, which typically have absorbent material, such as cotton, wrapped around their sampling ends. Before being placed into the sample container, the absorbent material of the sample carrier may have secretions, excrement, or animal or plant tissue fluid adhering to it. The sample carrier is placed into the sample container with its sampling end against the bottom, and the space in the sample container narrows towards its bottom center. Because the diameter of the rod-shaped component may be small, and the sample container itself is elongated, when the rod-shaped component is inserted into the sample container, there is a high chance that it will penetrate into the sampling end of the sample carrier. When the rod-shaped component leaves the current sample container, the sample carrier in the current sample container leaves the sample container with it, and may even enter the next sample container with it, causing cross-contamination between samples and affecting the accuracy of subsequent detection. In addition, if the rod-shaped component is attached to the sample-carrying component and moves, the rod-shaped component may get stuck or even break when passing through narrow spaces. Summary of the Invention

[0003] Therefore, it is necessary to provide a sample processing device, a sample analyzer, and a sample processing method to address the problem that the rod-shaped component may insert into the sampling end of the sample-bearing component when it is inserted into the sample container.

[0004] A sample processing apparatus, comprising:

[0005] A rod-shaped component for extending into a sample carrier for accommodating a sample adhered to it and a sample container for diluting the sample;

[0006] The control unit is used to control the rod-shaped component to extend into the sample container along the central region of the sample container, then control the rod-shaped component to move towards the side wall of the sample container, and then control the rod-shaped component to move towards the bottom of the sample container.

[0007] Before processing the diluent in the sample container, the aforementioned sample processing device requires inserting a rod-shaped component into the sample container. Due to the narrowing space at the bottom of the sample container, the sampling end of the sample-carrying component, such as a swab or cotton swab, automatically slides down and rests against the center of the bottom of the sample container. The rod-shaped component begins to enter the sample container along the central area, thus reliably avoiding the opening edge of the sample container and entering the relatively narrow opening. While inside the sample container, the rod-shaped component moves near the side wall of the sample container, avoiding the central area, and then moves towards the bottom of the sample container. This ensures that when the rod-shaped component reaches the bottom of the sample container, its end avoids the center of the bottom, preventing it from inserting into the sampling end of the sample-carrying component.

[0008] In one embodiment, the central region is the central region of the opening of the sample container.

[0009] In one embodiment, the control unit controls the rod-shaped member to extend into the sample container along the center of the opening of the sample container.

[0010] In one embodiment, when the control unit controls the rod-shaped component to extend, the length direction of the rod-shaped component remains parallel to the centerline of the sample container.

[0011] In one embodiment, the control unit controls the rod-shaped member to move closer to the side wall of the sample container after controlling the end of the rod-shaped member to extend to the middle position of the sample container in the depth direction.

[0012] In one embodiment, the control unit controls the rod-shaped component to move toward the side wall of the sample container after controlling the rod-shaped component to extend into a preset distance.

[0013] In one embodiment, after the rod-shaped component is moved to the bottom of the sample container, the control unit controls the rod-shaped component to stir the sample carrier and the diluent, causing the sample to detach from the sample carrier.

[0014] In one embodiment, the control unit controls the rod-shaped component to rotate around the sample carrier component to stir the sample carrier component and the diluent, causing the sample to detach from the sample carrier component.

[0015] A sample analyzer includes: a sample loading module, a detection module, and a sample processing device; the rod-shaped component is used to stir the sample carrier and the diluent in the sample container, causing the sample to detach from the sample carrier; the sample loading module is used to extract a quantitative sample from the sample container to the detection module, and the detection module is used to detect and analyze the quantitative sample.

[0016] A sample analyzer includes: an elution module, a detection module, and a sample processing device; the elution module is used to stir the sample carrier and the diluent in the sample container, causing the sample to detach from the sample carrier; the rod-shaped component is hollow, and the sample processing device extracts a quantitative sample from the sample container through the rod-shaped component; the detection module receives the quantitative sample extracted by the rod-shaped component and performs detection and analysis on the quantitative sample.

[0017] A sample processing method includes the following steps:

[0018] The insertion process involves inserting a rod-shaped component along the central region of the sample container into a sample carrier component that holds the sample and a sample container for diluting the sample.

[0019] The rod-shaped component moves towards the side wall of the sample container during the side-leaning process.

[0020] The deep-penetration process involves moving the rod-shaped component towards the bottom of the sample container. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the structure of a sample analyzer according to an embodiment of the present invention;

[0022] Figure 2 A side view of a sample processing apparatus according to an embodiment of the invention;

[0023] Figure 3 for Figure 2 The sample processing device shown is a front view.

[0024] Figure 4 A side view of a sample processing apparatus according to another embodiment of the invention;

[0025] Figure 5 for Figure 4 The sample processing device shown is a front view.

[0026] Figure 6 This is a flowchart of a sample processing method according to an embodiment of the present invention.

[0027] Figure label:

[0028] 10. Sample analyzer; 11. Elution module; 12. Sample loading module; 13. Detection module; 20a / 20b. Sample processing device; 30a / 30b. Rod-shaped component; 40a / 40b. Control unit; 41. Translation adjustment module; 411. Translation adjustment frame; 412. Translation driver; 42. First lifting adjustment module; 421. First lifting adjustment frame; 422. First lifting driver; 43. Stirring drive module; 431 432. Stirring actuator; 44. Base; 45. Horizontal adjustment module; 451. Horizontal frame; 452. Horizontal actuator; 46. Vertical adjustment module; 461. Vertical frame; 462. Vertical actuator; 47. Second lifting adjustment module; 471. Second lifting adjustment frame; 472. Second lifting actuator; 48. Stand; 500. Sample container; 501. Opening; 502a / 502b. Container support. Detailed Implementation

[0029] To make the above-mentioned objects, features, and advantages of the present invention more apparent and understandable, specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of the present invention. However, the present invention can be practiced in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0030] In the description of this invention, it should be understood that the terms "center," "longitudinal," "lateral," "length," "width," "thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," and "circumferential" indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0031] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this invention, "a plurality of" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0032] In this invention, unless otherwise explicitly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0033] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can mean that the first and second features are in direct contact, or that they are in indirect contact through an intermediate medium. Furthermore, "above," "over," and "on top" of the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0034] It should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.

[0035] The technical solutions provided by the embodiments of the present invention are described below with reference to the accompanying drawings.

[0036] The present invention provides a sample analyzer 10.

[0037] The sample analyzer 10 is used to detect samples of bodily fluids, secretions, excretions, or tissue fluid. In one embodiment, the sample analyzer 10 is used to detect and analyze gynecological secretions.

[0038] In some embodiments, human body fluids, tissue fluids, secretions, or excretions are sampled by a sample-bearing component, causing the sample to adhere to the sampling end of the component. In other embodiments, the body fluids, tissue fluids, secretions, or excretions of animals or plants may also be sampled by the sample-bearing component.

[0039] In some implementations, the sample carrier can be a cotton swab, a swab, or other component wrapped with absorbent material. Specifically, the absorbent material is generally located at the sampling end of the sample carrier, i.e., one end of the sample carrier, and the absorbent material can be cotton or other easily adhesive material.

[0040] After sampling by the sample carrier component, the sample carrier component is placed into the sample container 500, and the sampling end of the sample carrier component is immersed in the sample container 500 using a diluent. After the sample is detached from the sampling end of the sample carrier component, the diluent contains components of the sample. In one embodiment, the sample container 500 is a test tube.

[0041] exist Figure 1 In the illustrated embodiment, the sample analyzer 10 includes an elution module 11, a sample loading module 12 connected to the elution module 11, and a detection module 13 connected to the sample loading module 12. The elution module 11 accelerates the detachment of the sample from the sample carrier component, ensuring sufficient sample components in the diluent. Specifically, the elution module 11 agitates the sample carrier component and diluent within the sample container 500 using a stirring rod, accelerating the flow of the diluent within the sample container 500 and thus improving the efficiency of sample detachment from the sampling end of the sample carrier component. The sample loading module 12 extracts a quantitative sample containing sample components and diluent components from the sample container 500 to the detection module 13. Specifically, the sample loading module 12 delivers a quantitative sample from the sample container 500 to the detection module 13 using a sampling needle. The detection module 13 detects the quantitative sample extracted by the sample loading module 12. In some embodiments, the detection module 13 performs dry chemical analysis on the quantitative sample. In other embodiments, the detection module 13 performs morphological analysis on the quantitative sample. Alternatively, the detection module 13 is used to perform dry chemical detection, morphological detection and other detections to detect and confirm relevant parameters or properties of the sample.

[0042] The present invention provides a sample processing device 20a.

[0043] In some implementations, such as Figure 2As shown, the sample processing device 20a includes a rod-shaped component 30a and a control unit 40a. The sample container 500 is used to hold a sample carrier and a diluent. Specifically, the sample carrier has a sample adhered to it, and the diluent is used to dilute the sample. The rod-shaped component 30a extends into the sample container 500 to process the sample carrier or diluent within the sample container 500. More specifically, the control unit 40a controls the rod-shaped component 30a to extend into the sample container 500 along its central region, then controls the rod-shaped component 30a to move towards the side wall of the sample container 500, and then controls the rod-shaped component 30a to move towards the bottom of the sample container 500. Specifically, when the rod-shaped component 30a moves towards the side wall of the sample container 500, it moves from a position near the center of the sample container 500 towards the inner surface of the side wall of the sample container 500. In some embodiments, the sample container 500 is composed of a sidewall and a bottom; more specifically, the sidewall is tubular and the bottom is connected to one end of the sidewall.

[0044] Because the bottom space of the sample container 500 is narrowed, the sampling end of the sample-carrying component, such as a swab or cotton swab, automatically slides down and abuts against the center of the bottom of the sample container 500. The rod-shaped component 30a enters the sample container 500 along the central region, thus stably avoiding the edge of the opening 501 of the sample container 500 and reliably entering the relatively narrow opening 501 of the sample container 500. When the rod-shaped component 30a is inside the sample container 500, it moves close to the side wall of the sample container 500, avoids the central region of the sample container 500, and then moves towards the bottom of the sample container 500. This ensures that when the rod-shaped component 30a moves to the bottom of the sample container 500, the end of the rod-shaped component 30a avoids the center of the bottom of the sample container 500, preventing the rod-shaped component 30a from inserting into the sampling end of the sample-carrying component.

[0045] In some embodiments, the central region is the central region of the opening 501 of the sample container 500. In one embodiment, the central region is a circular region centered on the center of the opening 501 of the sample container 500, and the diameter of the central region is smaller than the inner diameter of the opening 501 of the sample container 500. Since the rod-shaped member 30a passes through the opening 501 of the sample container 500 from the central region, the end of the rod-shaped member 30a can easily avoid the edge of the opening 501 of the sample container 500, thus preventing collision between the end of the rod-shaped member 30a and the edge of the opening 501 of the sample container 500. In another embodiment, the central region is a region that coincides with the center of the opening 501 of the sample container 500 and has a shape similar to that of the opening 501 of the sample container 500, and the area of ​​the central region is smaller than the area of ​​the opening 501 of the sample container 500.

[0046] More specifically, the control unit 40a controls the rod-shaped member 30a to extend into the sample container 500 along the center of the opening 501. Therefore, even if the control unit 40a experiences a small deviation in controlling the movement of the rod-shaped member 30a, the rod-shaped member 30a can still remain within the central area despite the deviation, reducing the accuracy requirements on the control unit 40a. Understandably, the center of the opening 501 of the sample container 500 is the geometric center of the shape of the opening 501.

[0047] In some embodiments, when the control unit 40a controls the rod-shaped member 30a to extend, the length direction of the rod-shaped member 30a remains parallel to the centerline of the sample container 500. Specifically, the centerline of the sample container 500 is a straight line passing through the geometric center of the opening 501 of the sample container 500 along the depth direction of the sample container 500. Therefore, when the rod-shaped member 30a moves relative to the sample container 500, the radial distance between different parts of the rod-shaped member 30a and the sidewall of the sample container 500 is consistent, avoiding the need to continuously adjust the angle of the rod-shaped member 30a when it extends into the sample container 500. Specifically, the radial distance is the straight-line distance between the rod-shaped member 30a and the sidewall of the sample container 500 on a plane perpendicular to the depth direction of the sample container 500.

[0048] In some embodiments, after the control unit 40a controls the rod-shaped member 30a to extend into the sample container 500 to a preset distance, the control unit 40a controls the rod-shaped member 30a to move towards the side wall of the sample container 500. Specifically, the rod-shaped member 30a stops moving towards the side wall of the sample container 500 after moving to a position with a predetermined gap between it and the side wall of the sample container 500. By setting the predetermined gap, when the control unit 40a controls the rod-shaped member 30a to continue moving deeper into the bottom of the sample container 500, friction between the rod-shaped member 30a and the side wall of the sample container 500 can be avoided, ensuring the smooth movement of the rod-shaped member 30a and preventing wear on the rod-shaped member 30a or the sample container 500. Specifically, when the rod-shaped member 30a moves towards the side wall of the sample container 500, the rod-shaped member 30a may move in a direction perpendicular to the depth of the sample container 500.

[0049] In other embodiments, after the control unit 40a extends to the center position of the sample container 500 in the depth direction, the control rod-shaped member 30a moves towards the side wall of the sample container 500. Specifically, the center position of the sample container 500 in the depth direction is a position near the midpoint between its open end and closed end. Similarly, the rod-shaped member 30a stops moving towards the side wall of the sample container 500 when a predetermined gap exists between it and the side wall.

[0050] In some embodiments, when the control unit 40a controls the rod-shaped member 30a to move towards the bottom of the sample container 500, the length direction of the rod-shaped member 30a remains parallel to the center line of the sample container 500. Furthermore, before the end of the rod-shaped member 30a contacts the bottom of the sample container 500, the rod-shaped member 30a stops moving towards the bottom of the sample container 500 to avoid contact between the end of the rod-shaped member 30a and the sample container 500, and to prevent the rod-shaped member 30a from breaking due to contact.

[0051] In some embodiments, the sample processing device 20a serves as the elution module 11 described above, and the rod-shaped component 30a serves as a stirring rod.

[0052] Specifically, after the control rod-shaped component 30a moves to the bottom of the sample container 500, the control unit 40a controls the rod-shaped component 30a to stir the sample carrier component and the diluent, causing the sample to detach from the sample carrier component. Further, the control unit 40a controls the rod-shaped component 30a to rotate around the sample carrier component to stir the sample carrier component and the diluent, causing the sample to detach from the sample carrier component. When the rod-shaped component 30a rotates around the sample carrier component, the diluent around the sampling end of the sample carrier component generates a rotating flow around the sampling end, ensuring that the sampling end of the sample carrier component is flushed by the diluent at different angles, thus accelerating the detachment of the sample from the sample carrier component.

[0053] In some implementations, such as Figure 2As shown, multiple sample containers 500 are arranged side-by-side on a container support 502a, and a control unit 40a is located on one side of the container support 502a. Along the side-by-side direction of the multiple sample containers 500, the container support 502a can move the sample containers 500 relative to the control unit 40a. Specifically, the control unit 40a includes a translation adjustment module 41, a first lifting adjustment module 42, and a stirring drive module 43. The translation adjustment module 41 is used to drive the rod-shaped component 30a to move along a direction perpendicular to the straight line where the multiple sample containers 500 are arranged side-by-side. Simultaneously, the depth direction of the sample container 500 is perpendicular to the driving direction of the translation adjustment module 41 on the rod-shaped component 30a. Therefore, before the rod-shaped component 30a extends into the opening 501 of the sample container 500, the container support 502a drives the sample container 500, which requires stirring, to the position below the rod-shaped component 30a. The translation adjustment module 41 can be used to adjust the end of the rod-shaped component 30a to align it with the center area of ​​the opening 501 of the sample container 500. After the end of the rod-shaped component 30a extends into the sample container 500, the translation adjustment module 41 drives the rod-shaped component 30a to move closer to the side wall of the sample container 500. The first lifting adjustment module 42 drives the rod-shaped component 30a to move along the depth direction of the sample container 500, so that the rod-shaped component 30a can extend into the opening 501 of the sample container 500 and move towards the bottom of the sample container 500. The stirring drive module 43 is used to drive the rod-shaped component 30a to rotate around the stirring axis, so as to cause the diluent in the sample container 500 to flow and to cause the sample carrier component in the sample container 500 to rotate, thereby accelerating the detachment of the sample from the sample carrier component.

[0054] exist Figure 2 and Figure 3 In the illustrated embodiment, the control unit 40a further includes a base 44 disposed on one side of the container support 502a. The translation adjustment module 41 includes a translation adjustment frame 411 slidably connected to the base 44 and a translation driver 412 connected to the base 44. The translation driver 412 drives the translation adjustment frame 411 to move relative to the base 44. The first lifting adjustment module 42 and the stirring drive module 43 are mounted on the translation adjustment frame 411. Specifically, the sliding direction of the translation adjustment frame 411 relative to the base 44 is perpendicular to the side-by-side direction of the plurality of sample containers 500, and the translation adjustment frame 411 extends upward, i.e., extends away from the base 44. The translation driver 412 is used to drive the translation adjustment frame 411 to move away from or closer to the container support 502a.

[0055] exist Figure 2 In the embodiment shown, the translation driver 412 is a lead screw motor. The translation driver 412 cooperates with the nut mounted on the translation adjustment frame 411 to control the translation adjustment frame 411 and the rod-shaped component 30a in the direction of movement. Figure 2The position is shown in the horizontal direction. In an embodiment not shown in the figure, the translation driver 412 can also control the movement of the translation adjustment frame 411 by cooperating with a lead screw or other transmission components.

[0056] Specifically, the translation actuator 412 controls the movement distance of the translation adjustment frame 411 and the rod-shaped member 30a according to the control signal. Based on the known centerline position of the sample container 500, the inner diameter of the sample container 500, and the rotation feedback signal, the translation actuator 412 determines the relative position between the rod-shaped member 30a and the sample container 500. This enables the rod-shaped member 30a to enter the sample container 500 from the central region of the opening 501, and to move the rod-shaped member 30a accurately to a position with a predetermined gap from the side wall of the sample container 500.

[0057] In some embodiments, the first lifting adjustment module 42 includes a first lifting adjustment frame 421 slidably connected to the translation adjustment frame 411 and a first lifting driver 422 connected to the translation adjustment frame 411. The first lifting driver 422 is used to drive the first lifting adjustment frame 421 to move away from or towards the base 44. Specifically, the sliding connection direction between the first lifting adjustment frame 421 and the translation adjustment frame 411 is parallel to the depth direction of the sample container 500.

[0058] exist Figure 2 In the embodiment shown, the first lifting driver 422 is a lead screw motor. The first lifting driver 422 cooperates with a nut mounted on the first lifting adjustment frame 421 to control the first lifting adjustment frame 421 and the rod-shaped component 30a. Figure 2 The position is shown in the vertical direction. In an embodiment not shown in the figure, the first lifting driver 422 can also control the movement of the first lifting adjustment frame 421 by cooperating with a lead screw or other transmission components.

[0059] In some embodiments, the stirring drive module 43 includes a stirring driver 431, the output shaft of which drives the rod-shaped component 30a to rotate around the stirring axis. In one embodiment, the stirring axis coincides with the axis of the output shaft of the stirring driver 431. In another embodiment, the stirring driver 431 drives the rod-shaped component 30a to rotate via a stirring transmission member 432, the stirring axis coinciding with the rotation axis of the stirring transmission member 432. Specifically, the stirring driver 431 is a motor.

[0060] Furthermore, after the rod-shaped component 30a moves to the bottom of the sample container 500, the stirring axis coincides with the center line of the sample container 500 to avoid the rod-shaped component 30a hitting the side wall of the sample container 500 when rotating.

[0061] After the rod-shaped component 30a reaches the bottom of the sample container 500 and completes the stirring of the sample-bearing component and diluent, the first lifting adjustment module 42 causes the stirring rod to exit the sample container 500. Subsequently, the container support 502a moves each sample container 500 along the parallel direction of multiple sample containers 500, so that the next sample container 500 that needs to be stirred reaches the position below the rod-shaped component 30a. The translation adjustment module 41 and the first lifting adjustment module 42 control the rod-shaped component 30a to enter the sample container 500, and the stirring drive module 43 controls the rod-shaped component 30a to stir the sample container 500.

[0062] In other embodiments, the control unit 40a may be any structure that enables the rod-shaped component 30a to enter the sample container 500 in a predetermined manner.

[0063] In some other embodiments, the sample processing device 20b serves as the above-mentioned sample application module 12, and the rod-shaped component 30b serves as the sample application needle.

[0064] Specifically, such as Figure 4 and Figure 5 As shown, the control unit 40b includes a horizontal adjustment module 45, a vertical adjustment module 46, and a second lifting adjustment module 47. The horizontal adjustment module 45 drives the rod-shaped component 30b to move along a direction perpendicular to the parallel straight line containing the plurality of sample containers 500, and the vertical adjustment module 46 drives the rod-shaped component 30b to move along a direction parallel to the parallel straight line containing the plurality of sample containers 500. Simultaneously, the depth direction of the sample container 500 is perpendicular to the driving direction of the horizontal adjustment module 45 on the rod-shaped component 30b. Therefore, before the rod-shaped component 30b extends into the opening 501 of the sample container 500, the horizontal adjustment module 45 and the vertical adjustment module 46 can be used to adjust the end of the rod-shaped component 30b to align it with the central region of the opening 501 of the sample container 500. After the end of the rod-shaped component 30b extends into the sample container 500, the lateral adjustment module 45 or the longitudinal adjustment module 46 is used to drive the rod-shaped component 30b to move towards the side wall of the sample container 500. The second lifting adjustment module 47 is used to drive the rod-shaped component 30b to move along the depth direction of the sample container 500, so that the rod-shaped component 30b can extend into the opening 501 of the sample container 500 and can move towards the bottom of the sample container 500.

[0065] Specifically, the sample processing device 20b also includes a stand 48 disposed on one side of the container support 502b.

[0066] exist Figure 4In the illustrated embodiment, the lateral adjustment module 45 includes a lateral frame 451 slidably connected to the stand 48 and a lateral driver 452 connected to the stand 48. The lateral driver 452 drives the lateral frame 451 to move along a direction perpendicular to the parallel straight line of the plurality of sample containers 500. Specifically, the lateral driver 452 is a motor, and the lateral driver 452 drives the lateral frame 451 to move relative to the stand 48 via a belt. In some embodiments not shown in the figures, the lateral driver 452 may also be a lead screw motor, which drives the lateral frame 451 to move by cooperating with a nut.

[0067] exist Figure 5 In the illustrated embodiment, the longitudinal adjustment module 46 includes a longitudinal frame 461 slidably connected to the transverse frame 451 and a longitudinal driver 462 connected to the transverse frame 451. The longitudinal driver 462 drives the longitudinal frame 461 to move along a parallel direction parallel to the plurality of sample containers 500. Specifically, the longitudinal driver 462 is a lead screw motor, and the longitudinal driver 462 drives the longitudinal frame 461 to move by cooperating with a nut. More specifically, the direction in which the longitudinal frame 461 moves away from or towards the transverse frame 451 is parallel to the parallel direction of the plurality of sample containers 500.

[0068] exist Figure 6 In the illustrated embodiment, the second lifting adjustment module 47 includes a second lifting adjustment frame 471 slidably connected to the longitudinal transfer frame 461 and a second lifting driver 472 connected to the longitudinal transfer frame 461. The second lifting driver 472 is used to drive the second lifting adjustment frame 471 to move away from or towards the stand 48. Specifically, the sliding connection direction between the second lifting adjustment frame 471 and the longitudinal transfer frame 461 is parallel to the depth direction of the sample container 500. A rod-shaped component 30b is mounted on the lower side of the second lifting adjustment frame 471.

[0069] Furthermore, as a sample loading module 12, the sample processing device 20b may also be equipped with necessary auxiliary components as needed, such as a pump body for generating low pressure to draw quantitative samples into the hollow rod-shaped component 30b.

[0070] exist Figure 5In the illustrated embodiment, before the rod-shaped component 30b enters the opening 501 of the sample container 500, the transverse drive 452 moves the transverse frame 451 along a direction perpendicular to the parallel lines of the multiple sample containers 500. Simultaneously, the longitudinal drive 462 moves the longitudinal frame 461 along a direction parallel to the parallel lines of the multiple sample containers 500, so that the end of the rod-shaped component 30b is aligned with the central region of the opening 501 of the sample container 500 or with the center of the opening 501 of the sample container 500. Subsequently, the second lifting drive 472 moves the second lifting adjustment frame 471 and the rod-shaped component 30b along the depth direction of the sample container 500, so that the end of the rod-shaped component 30b enters the opening 501 of the sample container 500.

[0071] After the end of the rod-shaped component 30b extends to the middle position of the sample container 500 in the depth direction, or after the rod-shaped component 30b extends a predetermined distance into the sample container 500, in one embodiment, the transverse drive 452 drives the transverse frame 451 to move along a direction perpendicular to the parallel lines of the multiple sample containers 500, so that the rod-shaped component 30b approaches the side wall of the sample container 500. In another embodiment, the longitudinal drive 462 can drive the longitudinal frame 461 to move along a direction parallel to the parallel lines of the multiple sample containers 500, so that the rod-shaped component 30b approaches the side wall of the sample container 500. In one embodiment, the transverse drive 452 and the longitudinal drive 462 can simultaneously drive the rod-shaped component 30b to move, so that the rod-shaped component 30b approaches the side wall of the sample container 500.

[0072] In some embodiments, the second lifting actuator 472 drives the second lifting adjustment frame 471 and the rod-shaped component 30b to move further, causing the end of the rod-shaped component 30b to move closer to the bottom of the sample container 500. Combined with other necessary components, a low pressure is created within the rod-shaped component 30b, drawing the diluent from the sample container 500 into the hollow rod-shaped component 30b as a quantitative sample. Subsequently, driven by the horizontal adjustment module 45, the vertical adjustment module 46, and the second lifting adjustment module 47, the rod-shaped component 30b moves away from the sample container 500. Then, driven by the horizontal adjustment module 45, the vertical adjustment module 46, and the second lifting adjustment module 47, the rod-shaped component 30b moves to a position close to the detection module 13, releasing the temporarily stored quantitative sample into the detection module 13.

[0073] In other embodiments, while one end of the hollow rod-shaped component 30b is immersed in the diluent, the other end of the rod-shaped component 30b is connected to a pipe. With the assistance of a peristaltic pump or other necessary components, the quantitative sample passes through the rod-shaped component 30b and the pipe in sequence, and is then transported to the detection module 13 for detection.

[0074] This invention provides a sample processing method S600, such as... Figure 6 As shown, it includes the following steps:

[0075] In the insertion process S601, the rod-shaped component 30a extends into the sample container 500 along the central region of the sample container 500 to hold the sample carrier component on which the sample is adhered and the diluent used to dilute the sample.

[0076] In the side-leaning process S602, the rod-shaped component 30a moves toward the side wall of the sample container 500;

[0077] In the deep-penetration process S603, the rod-shaped component 30a moves towards the bottom of the sample container 500.

[0078] Specifically, in the insertion process S601, the central region is the central region of the opening 501 of the sample container 500. A gap is provided between the central region and the edge of the opening 501 of the sample container 500 to prevent the end of the rod-shaped member 30a from colliding with the edge of the opening 501 of the sample container 500, and to prevent the rod-shaped member 30a from falling outside the opening 501 of the sample container 500 due to deviation during downward movement. More specifically, the rod-shaped member 30a extends into the sample container 500 along the geometric center of the opening 501. When the rod-shaped member 30a passes through the central region, its length direction is parallel to the depth direction of the sample container 500 to simplify control of the rod-shaped member 30a in the depth direction of the sample container 500.

[0079] For the side-leaning process S602, in some embodiments, after the rod-shaped member 30a extends into the sample container 500 to a preset distance, the rod-shaped member 30a moves towards the side wall of the sample container 500. Specifically, the preset distance can be adjusted according to the depth of the sample container 500 to avoid the planar area that may come into contact with the sampling end of the sample-bearing component in advance. The rod-shaped member 30a stops moving towards the side wall of the sample container 500 when a predetermined gap exists between it and the side wall of the sample container 500. Alternatively, the rod-shaped member 30a stops moving towards the side wall of the sample container 500 after it leaves the central region, and the gap between the central region and the opening edge of the sample container 500 is greater than the diameter of the rod-shaped member 30a. More specifically, when the rod-shaped member 30a moves towards the side wall of the sample container 500, the length direction of the rod-shaped member 30a remains parallel to the depth direction of the sample container 500.

[0080] For the side-leaning process S602, in some other embodiments, after the end of the rod-shaped member 30a extends to the middle position of the sample container 500 in the depth direction, the rod-shaped member 30a moves towards the side wall of the sample container 500. Specifically, the middle position of the sample container 500 in the depth direction is the position near the midpoint between its open end and closed end. The rod-shaped member 30a stops moving towards the side wall of the sample container 500 when a predetermined gap exists between it and the side wall.

[0081] For the depth probe process S603, in some embodiments, after the rod-shaped member 30a moves to a predetermined gap with the sidewall of the sample container 500, the rod-shaped member 30a moves toward the bottom of the sample container 500. The rod-shaped member 30a stops moving toward the bottom of the sample container 500 before its end contacts the bottom of the sample container 500.

[0082] In some other embodiments of the deep exploration process S603, after the rod-shaped component 30a moves away from the central region, the rod-shaped component 30a moves toward the bottom of the sample container 500.

[0083] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0084] The embodiments described above are merely illustrative of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. A sample processing device, characterized by, The application comprises: a rod-shaped member for extending into a sample container for containing a sample-carrying member with a sample adhered thereto and a diluent for diluting the sample, the bottom space of the sample container being narrowed to allow a sampling end of the sample-carrying member to abut the center of the bottom of the sample container; a control unit for controlling the rod-shaped member to extend into the center region of the sample container, then to move the rod-shaped member toward the side wall of the sample container, and then to move the rod-shaped member toward the bottom of the sample container, and after the rod-shaped member is moved to the bottom of the sample container, the control unit controls the rod-shaped member to rotate around the sample-carrying member to stir the sample-carrying member and the diluent, so that the sample falls off the sample-carrying member.

2. The sample processing device of claim 1, wherein, The center region is the center region of the opening of the sample container.

3. The sample processing device of claim 1, wherein, The control unit controls the rod-shaped member to extend into the center of the opening of the sample container.

4. The sample processing device of claim 2, wherein, When the control unit controls the rod-shaped member to extend, the length direction of the rod-shaped member is parallel to the center line of the sample container.

5. The sample processing device of claim 1, wherein, The control unit controls the rod-shaped member to move toward the side wall of the sample container after controlling the end of the rod-shaped member to extend to the middle position of the sample container in the depth direction.

6. The sample processing device of claim 1, wherein, The control unit controls the rod-shaped member to move toward the side wall of the sample container after controlling the rod-shaped member to extend to a preset distance.

7. A sample analyzer characterized by, The application comprises: a sample adding module, a detection module, and a sample processing device according to any one of claims 1 to 6; the rod-shaped member is used to stir the sample-carrying member and the diluent in the sample container, so that the sample falls off the sample-carrying member; the sample adding module is used to extract a quantitative sample from the sample container to the detection module, and the detection module is used to detect and analyze the quantitative sample.

8. A sample processing method, characterized by, The application comprises the following steps: a probe processing, a rod-shaped member extends into a sample container for containing a sample-carrying member with a sample adhered thereto and a diluent for diluting the sample along the center region of the sample container, the bottom space of the sample container is narrowed to allow a sampling end of the sample-carrying member to abut the center of the bottom of the sample container, and when the rod-shaped member passes through the center region, the length direction of the rod-shaped member is parallel to the depth direction of the sample container; a side leaning processing, the rod-shaped member moves toward the side wall of the sample container; a deep probe processing, the rod-shaped member moves toward the bottom of the sample container, and after the rod-shaped member is moved to the bottom of the sample container, the control unit controls the rod-shaped member to rotate around the sample-carrying member to stir the sample-carrying member and the diluent, so that the sample falls off the sample-carrying member.

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