A continuous coating device for sustained-release tablets

By using a continuous coating device with a purely mechanical structure, the safety and yield issues in the coating process of sustained-release tablets have been solved. This has enabled a highly efficient and safe coating process without the need for volatile solvents, and has also improved the adhesion and aesthetics of the coating.

CN115919650BActive Publication Date: 2025-12-02SHANGHAI UNIV OF ENG SCI
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Patent Information

Application Number
CN202211392799.4
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-03-03
Publication Date
2025-12-02
Estimated Expiration
2043-03-03

AI Technical Summary

Technical Problem

Existing continuous coating devices for sustained-release tablets have problems such as the use of flammable and explosive volatile organic solvents, high manufacturing costs, large coating edge allowances requiring additional trimming, and the detection process being prone to problems.

Method used

The continuous coating device, which adopts a purely mechanical structure, includes die forming, heat sealing, punching and piercing mechanisms. It has a built-in trimming function and achieves the coating of controlled-release tablets through mechanical transmission, avoiding the use of volatile organic solvents. During the piercing process, it adaptively adjusts the positional relationship to improve accuracy.

Benefits of technology

It improves production safety and yield, reduces manufacturing costs, enhances production efficiency, and reduces additional processing steps through its built-in trimming function, ensuring the fit and aesthetics of the coating.

✦ Generated by Eureka AI based on patent content.

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Abstract

This invention provides a continuous coating apparatus for sustained-release tablets. The apparatus comprises a die-forming mechanism, a feeding mechanism, a heat-sealing mechanism, a punching mechanism, a shifting mechanism, and a perforation mechanism, all mounted on a frame along the coating conveying direction. The die-forming mechanism forms pores on the lower coating layer to accommodate the sustained-release tablets. The feeding mechanism lays each sustained-release tablet flat into its corresponding pore. The heat-sealing, punching, and perforation mechanisms are respectively used to seal the sustained-release tablets using the upper and lower coating layers, punch holes in the sealed tablets, and cut them from the coating layer. The perforation mechanism employs a stamping structure, with a centering mechanism and a trimming mechanism arranged from top to bottom along the stamping direction. The centering mechanism gathers the sustained-release tablets in the coating layer into the pores in the lower die, and the trimming mechanism trims the punched tablets. The shifting mechanism employs an intermittent motion structure, enabling the upper and lower coating layers to move together along the coating conveying direction.
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Description

Technical Field

[0001] This invention belongs to the technical field of tablet preparation, and specifically relates to a continuous coating device for sustained-release tablets. Background Technology

[0002] Coating of slow-release tablets is usually achieved through spray coating technology. Before spraying, the polymer generally needs to be dissolved in an organic solvent or dispersed in water to prepare a coating solution or dispersion. After atomization in a specific device, it is repeatedly sprayed and dried to adhere to the tablet surface to complete the coating. The disadvantages of this method are: the volatile organic solvents used are flammable and explosive, and the corresponding explosion-proof workshops and pollution recovery devices increase the manufacturing cost; at present, the continuous coating devices for slow-release tablets at home and abroad have a large coating edge allowance in the shape of the final tablet. When the allowance is too large, further coating trimming is required. At the same time, a large number of sensors are used for detection, and problems are prone to occur during operation. Summary of the Invention

[0003] To address the shortcomings of existing technologies, this invention provides a continuous coating device for sustained-release tablets. It employs a purely mechanical structure to complete the coating of sustained-release tablets, eliminating the need for excessive chemical agents such as volatile organic solvents, resulting in high safety and low manufacturing costs. Furthermore, the punching mechanism in this continuous coating device has a built-in trimming function, eliminating the need for additional trimming, leading to a high yield and effectively improving production efficiency. It is highly practical and easy to promote and apply.

[0004] To achieve the above objectives, the present invention provides the following technical solution:

[0005] A continuous coating apparatus for sustained-release tablets includes a frame. On the frame, along the coating conveying direction, are arranged a die-forming mechanism, a feeding mechanism, a heat-sealing mechanism, a punching mechanism, a shifting mechanism, and a perforating mechanism. Below the coating conveying direction, a lower coating unwinding mechanism is arranged; above, an upper coating unwinding mechanism and a waste material winding mechanism are arranged.

[0006] The membrane pore forming mechanism is used to form membrane pores for accommodating controlled-release tablets on the lower coating, and the feeding mechanism is used to feed the controlled-release tablets and lay each controlled-release tablet flat into the corresponding membrane pores.

[0007] The heat-sealing mechanism, punching mechanism, and perforation mechanism are respectively used to seal the controlled-release tablets using the upper and lower coatings, to punch holes in the sealed controlled-release tablets, and to cut the sealed controlled-release tablets out of the coatings.

[0008] The punching mechanism adopts a stamping structure, and a centering mechanism and a trimming mechanism are arranged from top to bottom along the stamping direction. The centering mechanism is used to gather the controlled-release tablets in the coating into the corresponding punching holes in the lower template, and the trimming mechanism is used to trim the stamped controlled-release tablets.

[0009] The actuation mechanism adopts an intermittent motion structure, enabling the upper and lower coatings to move together along the coating conveying direction.

[0010] Furthermore, the punching mechanism includes a punch top plate and a lower module arranged vertically and vertically. Multiple punches facing the lower module are evenly spaced on the punch top plate, and multiple punch holes corresponding to the punches are evenly spaced on the lower module.

[0011] A centering mechanism is provided along the axial direction of each punch. The centering mechanism includes a sliding ring and a fixed ring that are fitted onto the punch at intervals. The sliding ring slides along the axial direction of the punch, and the fixed ring is fixed to the punch. Multiple springs are evenly spaced along the circumference of the sliding ring. The free end of each spring is curved and extends downwards through a corresponding through hole on the fixed ring.

[0012] As the lower template moves upward, it pushes each spring to move upward along the axial direction of the punch, thereby actuating the controlled-release sheet in the coating to retract into the corresponding punching hole in the lower template; as the lower template moves downward, each spring moves downward along the axial direction of the punch under the action of gravity until the sliding ring contacts the fixed ring.

[0013] Below each punched hole in the lower module, a trimming mechanism is provided. The trimming mechanism includes a heating channel corresponding to the punched hole in the lower module. A heat-conducting ring is connected to the bottom surface of the heating channel. Multiple arc-shaped openings are evenly distributed on the side wall of the heat-conducting ring. Each arc-shaped opening is provided with a matching arc-shaped stop. Each arc-shaped stop includes an arc-shaped body. A limiting block is provided on the top surface of the arc-shaped body. The limiting block abuts against the notch inside the outer side wall of the heat-conducting ring corresponding to the arc-shaped opening.

[0014] The inner wall of the arc-shaped body protrudes into the interior of the heat-conducting ring, and an arc-shaped guide groove is provided along its outer wall. A spring is fitted on the outer side of the side wall of the heat-conducting ring. The spring cooperates with the arc-shaped guide groove to achieve elastic contact between the limiting block of the arc-shaped stop and the notch of the heat-conducting ring.

[0015] Furthermore, the free end of the reed extends away from the center of the punch, and a friction surface is provided on the inner wall of the arc-shaped body.

[0016] Furthermore, both the heat sealing mechanism and the punching mechanism adopt a clamp-type structure, and they share a drive mechanism with the punching mechanism. The drive mechanism adopts a cam-type structure, which is used to control the back-and-forth movement of the lower template of the heat sealing mechanism, the punching mechanism and the punching mechanism to achieve the corresponding functions.

[0017] Furthermore, the drive mechanism includes a drive wheel and a driven wheel connected by a belt. The central shaft of the drive wheel is connected to the output shaft of the first motor. A transmission shaft is disposed at the center of the driven wheel. Three cams are disposed on the transmission shaft. The three cams are respectively disposed below the lower templates of the heat sealing mechanism, the punching mechanism, and the perforation mechanism, and cooperate with the free ends of push rods disposed on the bottom surface of the corresponding lower templates.

[0018] The first motor is used to drive three cams to rotate simultaneously via belt transmission, so that the corresponding push rods and cams make contact at different positions, thereby driving the corresponding lower template to move up and down.

[0019] Furthermore, the actuating mechanism includes an intermittent motion mechanism, the output end of which is connected to the side of the moving plate. A first pneumatic clamping mechanism is provided on the top surface of the moving plate. The first pneumatic clamping mechanism is used to clamp or release the upper coating, the lower coating, and the controlled-release tablets therein.

[0020] The gap motion mechanism is used to drive the moving plate together with the first pneumatic clamping mechanism to move back and forth along the coating conveying direction to realize coating conveying.

[0021] Furthermore, the intermittent motion mechanism includes a second motor, the output shaft of which is connected to the center of the turntable. A limit pin is provided on the turntable, and the limit pin is engaged in an arc-shaped track groove. The arc-shaped track groove is formed on a synchronization plate, and an extension rod is provided on each side of the synchronization plate. The free end of each extension rod is engaged in a corresponding fixed slide groove.

[0022] The synchronization plate is also connected to one end of a connecting rod, and the other end of the connecting rod is connected to a slider. The slider is mounted on a slide rail and is also connected to the side of a moving plate. The slide rail is arranged along the coating conveying direction.

[0023] The first pneumatic clamping mechanism clamps the upper coating, the lower coating and the slow-release tablet therein. Then the second motor drives the turntable to rotate, so that the limit pin on the turntable moves along the arc-shaped track groove, thereby driving the synchronous plate and the slider to move along the coating conveying direction. In this way, the moving plate drives the first pneumatic clamping mechanism to move along the coating conveying direction, thereby realizing the coating conveying.

[0024] The first pneumatic clamping mechanism releases the upper coating, lower coating, and the slow-release tablet therein. Then, the second motor drives the turntable to continue rotating, causing the limit pin on the turntable to continue moving along the arc-shaped track groove. This, along with the slider, drives the first pneumatic clamping mechanism on the moving plate to move in the opposite direction of the coating conveying direction and return to its original position.

[0025] Furthermore, a second pneumatic clamping mechanism is provided between the actuating mechanism and the punching mechanism. The second pneumatic clamping mechanism is used to clamp or release the upper coating, the lower coating, and the controlled-release tablet therein.

[0026] The feeding mechanism includes an L-shaped cavity, inside which are three parallel feeding channels that together form a Y-shaped structure.

[0027] Inside the horizontal part of the L-shaped cavity, a brush disc, a stop plate, and a pressing roller are arranged sequentially along the coating conveying direction. A gap is left between the bottom surface of each of them and the top surface of the lower coating. The center of the brush disc is connected to the output shaft of the reduction motor, which is used to drive the brush disc to rotate.

[0028] Compared with the prior art, the beneficial effects of the present invention are:

[0029] The punching mechanism of the continuous coating apparatus of the present invention can adaptively adjust the positional relationship between the punching edge and the patch-coated controlled-release tablet, thereby improving the accuracy of the punching position. On the other hand, it can further trim the edge of the patch-coated controlled-release tablet. The coated controlled-release tablets produced under the action of this apparatus can have better fit and aesthetics, without the need for additional trimming, resulting in a higher yield and effectively improving production efficiency.

[0030] Meanwhile, except for the actuation mechanism, all other components adopt a simple, purely mechanical transmission method. The heat-sealing assembly, the punching assembly, and the perforation assembly all complete their respective actions under the action of the transmission components on the same shaft, which has higher reliability. In addition, the drive mechanism and the actuation mechanism that work together on the heat-sealing assembly, the punching assembly, and the perforation assembly can be connected together by bevel gear meshing transmission, sharing a single motor, which can further reduce the size of the device and reduce the complexity of the structure. Attached Figure Description

[0031] Figure 1 This is a schematic diagram of the overall device of the present invention. Figure 1 ;

[0032] Figure 2 This is a schematic diagram of the overall device of the present invention. Figure 2 ;

[0033] Figure 3 This is a schematic diagram of the rear structure of the overall device of the present invention;

[0034] Figure 4 This is a schematic diagram of the feeding mechanism of the present invention;

[0035] Figure 5 This is a cross-sectional schematic diagram of the feeding channel of the present invention;

[0036] Figure 6 This is a schematic diagram of the cooperative structure of the driving mechanism and the actuating mechanism of the present invention;

[0037] Figure 7 This is a schematic diagram of the punching mechanism of the present invention;

[0038] Figure 8 This is a schematic diagram showing the fit between the heat-conducting ring and the arc-shaped stop block of the present invention;

[0039] Figure 9 This is a schematic diagram of the arc-shaped stop block of the present invention;

[0040] The components are: 1-frame, 2-upper coating unwinding mechanism, 3-waste material winding mechanism, 4-die forming mechanism, 5-unloading mechanism, 501-L-shaped cavity, 502-unloading channel, 503-brush disc, 504-stop plate, 505-pressing roller, 506-gear motor, 6-heat sealing mechanism, 7-drilling mechanism, 8-pushing mechanism, 801-moving plate, 802-first pneumatic clamping mechanism, 803-turntable, 804-limit pin, 805-arc-shaped track groove, 806-fixed slide groove, 807-connecting rod, 808-slide rail, 809-motor, 8 10-Bevel gear, 9-Punching mechanism, 901-Punch top plate, 902-Lower template, 903-Punch, 904-Punching, 905-Sliding ring, 906-Fixing ring, 907-Spring, 908-Heating channel, 909-Heat-conducting ring, 910-Arc-shaped stop, 9101-Limit block, 9102-Arc-shaped guide groove, 911-Spring, 10-Lower coating unwinding mechanism, 11-Drive mechanism, 1101-Driving wheel, 1102-Driven wheel, 1103-Drive shaft, 1104-Cam, 1105-Push rod, 12-Second pneumatic clamping mechanism. Detailed Implementation

[0041] To make the technical means, creative features, objectives and effects of this invention easier to understand, the following embodiments are described in detail with reference to the accompanying drawings. It should be noted that the description of these embodiments is for the purpose of helping to understand this invention, but does not constitute a limitation of this invention.

[0042] It should be noted that in the description of this invention, the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing the invention and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the invention. The terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Furthermore, unless otherwise explicitly specified and limited, the terms "installed," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal communication of two elements. When two elements are "fixedly connected" or "rotationally connected," the two elements can be directly connected or there may be an intermediate element. Conversely, when an element is referred to as being "directly on" another element, there is no intermediate element. The fixed or fixed connection method can be screwed, welded, riveted, plugged, or connected through a third component. Those skilled in the art will understand the specific meaning of the above terms in this invention based on the specific circumstances.

[0043] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the scope of the invention.

[0044] like Figure 1-3As shown, the present invention provides a continuous coating apparatus for sustained-release tablets, including a frame. A die-forming mechanism, a feeding mechanism, a heat-sealing mechanism, a punching mechanism, a shifting mechanism, and a perforating mechanism are arranged on the frame along the coating conveying direction. A lower coating unwinding mechanism is arranged below the coating conveying direction, an upper coating unwinding mechanism is arranged above the frame, and a waste material winding mechanism is arranged above the frame. The die-forming mechanism is used to form membrane holes for accommodating sustained-release tablets on the lower coating. The feeding mechanism is used to feed the sustained-release tablets and lay each sustained-release tablet flat into its corresponding membrane hole. The heat-sealing mechanism... The punching mechanism and the perforation mechanism are used to encapsulate the controlled-release tablets using the upper and lower coatings, punch holes in the encapsulated controlled-release tablets, and cut the encapsulated controlled-release tablets out of the coating, respectively. The perforation mechanism adopts a stamping structure, with a centering mechanism and a trimming mechanism arranged from top to bottom along the stamping direction. The centering mechanism is used to gather the controlled-release tablets in the coating into the corresponding punching holes in the lower template, and the trimming mechanism is used to trim the stamped controlled-release tablets. The actuation mechanism adopts an intermittent motion structure to realize that the upper and lower coatings move together along the coating conveying direction. In this way, the coating is conveyed through a toggle mechanism, passing sequentially through a die-forming mechanism, a feeding mechanism, a heat-sealing mechanism, a punching mechanism, and a perforation mechanism, achieving continuous coating operation. This process eliminates the need for volatile solvents, produces no dust, and ensures high safety. Simultaneously, the perforation mechanism has built-in centering and trimming functions, adaptively adjusting the positional relationship between the perforated edge and the controlled-release tablet, improving the accuracy of the perforation position. No additional trimming is required, resulting in a high yield and effectively improving production efficiency, facilitating widespread application. Details are as follows:

[0045] We can make the frame 1 into a frame structure, with a support plate on its top surface. The support plate is used to set up the upper coating unwinding mechanism 2 and the waste material winding mechanism 3. The frame can be a cuboid, with a die forming mechanism 4, a feeding mechanism 5, a heat sealing mechanism 6, a punching mechanism 7, a toggle mechanism 8 and a punching mechanism 9 on it for coating conveying. The frame can be equipped with a corresponding transmission mechanism and a lower coating unwinding mechanism 10.

[0046] The die-forming mechanism 4 includes a T-shaped top plate, which is connected to a lifting cylinder. The bottom surface of the vertical part is connected to an upper heating plate, and the bottom surface of the horizontal part is connected to an upper pressure plate. A lower heating plate and a lower film plate are arranged opposite to the upper heating plate and the upper pressure plate. Thus, under the drive of the lower coating unwinding mechanism, the lower coating is heated first and then the film is formed, thereby providing a storage cavity for the subsequent controlled-release tablets and completing the first step of coating.

[0047] like Figure 4-5As shown, the feeding mechanism 5 includes an L-shaped cavity 501. Inside the vertical part of the L-shaped cavity 501, three parallel feeding channels 502 are arranged, forming a Y-shaped structure. An inlet is provided at the front end. Inside the horizontal part of the L-shaped cavity 501, along the coating conveying direction, a brush disc 503, a stop plate 504, and a pressing roller 505 are arranged in sequence. An outlet is provided at the rear end. A gap is left between the bottom surface of each of them and the top surface of the lower coating. The size of the gap can be determined according to the actual situation. The center of the brush disc 503 is connected to the output shaft of the reduction motor 506. The reduction motor 506 is used to drive the brush disc 503 to rotate, thereby pulling the controlled-release tablets accumulated on the surface of the membrane pores of the lower coating to the periphery or into the membrane pores. The stop plate 504 can prevent the controlled-release tablets from moving around. The pressing roller 505 can continue to press the controlled-release tablets into the membrane pores for subsequent processes.

[0048] Both the heat-sealing mechanism 6 and the punching mechanism 7 adopt a clamp-type structure, such as an upper template and a lower template set at intervals. The bottom surface of the upper template in the heat-sealing mechanism 6 is equipped with a heating plate and a partition to cooperate with the lower template to achieve heat sealing. The purpose of adding the partition is to avoid excessive heating temperature and damage to the coating. The bottom surface of the upper template in the punching mechanism 7 is evenly spaced with multiple needle-like protrusions to punch holes in the heat-sealed tablets.

[0049] The heat sealing mechanism 6, the punching mechanism 7, and the punching mechanism 9 share a common drive mechanism 11. The drive mechanism 11 adopts a cam-type structure and is used to control the back-and-forth movement of the lower templates of the heat sealing mechanism 6, the punching mechanism 7, and the punching mechanism 9 to achieve the corresponding functions.

[0050] like Figure 6 As shown, the drive mechanism 11 includes a drive wheel 1101 and a driven wheel 1102 connected by a belt. The central axis of the drive wheel 1102 is connected to the output shaft of the first motor. A transmission shaft 1103 is provided at the center of the driven wheel 1101. Three cams 1104 are provided on the transmission shaft 1103. The three cams 1104 are respectively located below the lower templates of the heat sealing mechanism 6, the punching mechanism 7, and the punching mechanism 9. They cooperate with the free ends of push rods 1105 located on the bottom surface of the corresponding lower templates. The free ends of the push rods 1105 are arc-shaped to facilitate surface contact of the cams. Thus, driven by the first motor, the three cams are driven to rotate simultaneously by the belt transmission, so that the corresponding push rods and cams contact different positions, thereby driving the corresponding lower templates to move up and down, realizing the functions of the heat sealing mechanism, the punching mechanism, and the punching mechanism.

[0051] like Figure 7-9As shown, the punching mechanism 9 includes a punch top plate 901 and a lower module 902 arranged vertically and vertically. Multiple punches 903 facing the lower module are evenly spaced on the punch top plate 901. Multiple punches 904 corresponding to the punches are evenly spaced on the lower module 902. A centering mechanism is provided along the axial direction of each punch. The centering mechanism includes a sliding ring 905 and a fixed ring 906, which are spaced vertically and fitted onto the punch. The sliding ring 905 slides along the axial direction of the punch, and the fixed ring 906 is fixed to the punch. Multiple punches 904 are evenly spaced along the circumference of the sliding ring 905. The free end of each spring 907 is curved and extends away from the center of the punch. It extends downward to the lower module 902 through the corresponding through hole on the fixing ring 906. As the lower template 902 moves upward, it pushes each spring 907 to move upward along the axis of the punch. Since the free end of the spring 907 is arc-shaped, the upward-moving spring 907 will be in a contracted state, which can push the controlled-release tablet in the coating to retract into the corresponding punch in the lower template 902, realize the centering effect, and ensure that the controlled-release tablet can accurately enter the punch.

[0052] Conversely, as the lower template 902 moves downward, the thrust on the spring 907 disappears, and each spring 907 moves downward along the axis of the punch under the action of gravity until the sliding ring 905 contacts the fixed ring 906. The spring 907 then returns to its original state, preparing for the next alignment.

[0053] In the lower module 902, a trimming mechanism is provided below each punch hole. This trimming mechanism includes a heating channel 908 corresponding to the punch hole in the lower module. A heat-conducting ring 909 is connected to the bottom surface of the heating channel 908. Multiple arc-shaped openings are evenly spaced on the sidewall of the heat-conducting ring 909. Each arc-shaped opening is provided with a matching arc-shaped stop 910. Each arc-shaped stop 910 includes an arc-shaped body, and a limit block 9101 is provided on the top surface of the arc-shaped body. The limiting block 9101 abuts against the notch on the outer side wall of the heat-conducting ring 909 corresponding to the arc-shaped opening, so that the arc-shaped block can be embedded in the heat-conducting ring 909. The inner wall of the arc-shaped body protrudes into the heat-conducting ring 909, making the inner cavity formed by multiple arc-shaped blocks smaller than the inner cavity of the heat-conducting ring 909. At the same time, a friction surface is provided on the inner wall of the arc-shaped body. When the controlled-release tablet falls under the action of the punch, it helps to eliminate the edge of the controlled-release tablet that has been punched off, resulting in a better trimming effect.

[0054] In addition, an arc-shaped guide groove 9102 is provided along the outer wall of the arc-shaped stop 910, and a spring 911 is fitted on the outer side of the side wall of the heat-conducting ring 909. The spring 911 cooperates with the arc-shaped guide groove 9102 to achieve elastic contact between the limiting block 9101 of the arc-shaped stop and the notch of the heat-conducting ring 909. This allows the size of the inner cavity formed by multiple arc-shaped stops to be adaptively adjusted according to the size of the controlled-release sheet after punching, ensuring that the edge of the controlled-release sheet can fully contact the friction surface on the inner wall of the arc-shaped body, effectively improving the trimming effect. At the same time, the arc-shaped body of the arc-shaped stop 910, the heating channel 908, and the upper edge of the punch are all provided with chamfers to facilitate the entry of the controlled-release sheet.

[0055] The actuating mechanism 8 includes an intermittent motion mechanism. The output end of the intermittent motion mechanism is connected to the side of the moving plate 801. A first pneumatic clamping mechanism 802 is provided on the top surface of the moving plate 801. The first pneumatic clamping mechanism 802 is used to clamp or release the upper coating, the lower coating, and the controlled-release tablet therein. The intermittent motion mechanism is used to drive the moving plate 801 together with the first pneumatic clamping mechanism 802 to move back and forth along the coating conveying direction to realize coating conveying. The intermittent motion can be realized by a linkage structure, such as including a second electric motor. The output shaft of the second motor is connected to the center of the turntable 803. A limit pin 804 is provided on the turntable 803. The limit pin 804 is locked in the arc-shaped track groove 805. The arc-shaped track groove 805 is opened on the synchronous plate. An extension rod is provided on each side of the synchronous plate. The free end of each extension rod is locked in the corresponding fixed slide groove 806. The fixed slide groove 806 can be set on the frame 1 to fix the synchronous plate. At the same time, the setting direction of the extension rod is consistent with the coating conveying direction, but perpendicular to the axial direction of the turntable 803.

[0056] The synchronization plate is also connected to one end of the connecting rod 807, and the other end of the connecting rod 807 is connected to the slider, which is set on the slide rail 808 and is also connected to the side of the moving plate 801. The slide rail 808 is set along the coating conveying direction.

[0057] Since the center of the arc-shaped track groove 805 does not coincide with the center of the turntable 803, the relative position of the center and the arc of the arc-shaped track groove 805 can be determined according to the actual needs of the coating conveying distance. In this way, the second motor drives the limiting pin 804 on the turntable 803 to move back and forth along the arc-shaped track groove 805, so as to drive the synchronous plate and the slider to move back and forth along the slide rail 808, i.e., the coating conveying direction, to realize the coating conveying. Specifically, when the first pneumatic clamping mechanism clamps the upper coating, the lower coating and the slow-release tablet therein, the second motor drives the turntable to rotate, so that the limiting pin on the turntable moves along the arc-shaped track groove, thereby converting the rotation of the turntable into the linear movement of the synchronous plate, so as to drive the synchronous plate and the slider to move along the coating conveying direction, thereby driving the first pneumatic clamping mechanism to move along the coating conveying direction through the moving plate, so as to realize the coating conveying.

[0058] When the first pneumatic clamping mechanism releases the upper coating, lower coating, and the slow-release tablet therein, the second motor drives the turntable to continue rotating, causing the limit pin on the turntable to continue moving along the arc-shaped track groove, so that the first pneumatic clamping mechanism on the moving plate, together with the slider, drives the moving plate to move in the opposite direction of the coating conveying direction and return to its original position.

[0059] Considering the size and complexity of the device, we can use bevel gear meshing transmission to connect the actuating mechanism and the driving mechanism together, sharing a single motor 809. For example, the central shaft of one bevel gear 810 in the meshing mechanism can be connected to the central shaft of the turntable in the actuating mechanism, and the other bevel gear 810 can be mounted on the transmission shaft 1103 of the driving mechanism and connected to the driven wheel on it. At this time, the central hole of the driven wheel should be larger than the diameter of the transmission shaft and should not be in contact with the transmission shaft, but should still be connected to the driving wheel through a belt. In this way, the first motor in the driving mechanism can drive the transmission shaft and the turntable to rotate through belt transmission and bevel gear transmission, so as to complete the movement of the heat sealing mechanism, punching mechanism, drilling mechanism and actuating mechanism.

[0060] In addition, to better support the coating, a second pneumatic clamping mechanism 12 is provided between the actuating mechanism 8 and the punching mechanism 9. The second pneumatic clamping mechanism 12 is used to clamp or release the upper coating, the lower coating and the controlled-release tablet therein. When the first pneumatic clamping mechanism 802 moves the coating to the side of the second pneumatic clamping mechanism 12, the first pneumatic clamping mechanism 802 releases the coating and the second pneumatic clamping mechanism 12 clamps the coating to facilitate the subsequent execution of the punching mechanism 9.

[0061] The above embodiments are preferred embodiments of the present invention and are not intended to limit the scope of protection of the present invention. Various modifications or variations that can be made by those skilled in the art without creative effort within the scope of the appended claims are still within the scope of protection of this patent.

Claims

1. A continuous coating device for sustained-release tablets, characterized in that: The system includes a frame, on which, along the coating conveying direction, are arranged a die forming mechanism, a feeding mechanism, a heat sealing mechanism, a punching mechanism, a tossing mechanism, and a punching mechanism. Below the coating conveying direction, a lower coating unwinding mechanism is arranged, and above it, an upper coating unwinding mechanism and a waste material winding mechanism are arranged. The die-forming mechanism is used to form membrane pores on the lower coating to accommodate the controlled-release tablets, and the feeding mechanism is used to feed the controlled-release tablets and lay each controlled-release tablet flat into the corresponding membrane pores. The heat-sealing mechanism, punching mechanism, and perforation mechanism are respectively used to seal the controlled-release tablets using the upper and lower coatings, to punch holes in the sealed controlled-release tablets, and to cut the sealed controlled-release tablets out of the coatings. The punching mechanism adopts a stamping structure, and a centering mechanism and a trimming mechanism are arranged from top to bottom along the stamping direction. The centering mechanism is used to gather the controlled-release tablets in the coating into the corresponding punching holes in the lower template, and the trimming mechanism is used to trim the stamped controlled-release tablets. The actuation mechanism adopts an intermittent motion structure, enabling the upper and lower coatings to move together along the coating conveying direction; The punching mechanism includes a punch top plate and a lower module arranged vertically and vertically. Multiple punches facing the lower module are evenly spaced on the punch top plate, and multiple punch holes corresponding to the punches are evenly spaced on the lower module. A centering mechanism is provided along the axial direction of each punch. The centering mechanism includes a sliding ring and a fixed ring that are fitted onto the punch at intervals. The sliding ring slides along the axial direction of the punch, and the fixed ring is fixed to the punch. Multiple springs are evenly spaced along the circumference of the sliding ring. The free end of each spring is curved and extends downwards through a corresponding through hole on the fixed ring. As the lower template moves upward, it pushes each spring to move upward along the axial direction of the punch, thereby actuating the controlled-release sheet in the coating to retract into the corresponding punching hole in the lower template; as the lower template moves downward, each spring moves downward along the axial direction of the punch under the action of gravity until the sliding ring contacts the fixed ring. Below each punched hole in the lower module, a trimming mechanism is provided. The trimming mechanism includes a heating channel corresponding to the punched hole in the lower module. A heat-conducting ring is connected to the bottom surface of the heating channel. Multiple arc-shaped openings are evenly distributed on the side wall of the heat-conducting ring. Each arc-shaped opening is provided with a matching arc-shaped stop. Each arc-shaped stop includes an arc-shaped body. A limiting block is provided on the top surface of the arc-shaped body. The limiting block abuts against the notch inside the outer side wall of the heat-conducting ring corresponding to the arc-shaped opening. The inner wall of the arc-shaped body protrudes into the interior of the heat-conducting ring, and an arc-shaped guide groove is provided along its outer wall. A spring is fitted on the outer side of the side wall of the heat-conducting ring. The spring cooperates with the arc-shaped guide groove to achieve elastic contact between the limiting block of the arc-shaped stop and the notch of the heat-conducting ring.

2. The continuous coating apparatus for sustained-release tablets according to claim 1, characterized in that: The free end of the spring extends away from the center of the punch, and a friction surface is provided on the inner wall of the arc-shaped body.

3. The continuous coating apparatus for sustained-release tablets according to claim 1, characterized in that: The heat sealing mechanism and the punching mechanism both adopt a clamp-type structure, and they share a drive mechanism with the punching mechanism. The drive mechanism adopts a cam-type structure to control the back-and-forth movement of the lower templates of the heat sealing mechanism, the punching mechanism and the punching mechanism to achieve the corresponding functions.

4. The continuous coating apparatus for sustained-release tablets according to claim 3, characterized in that: The drive mechanism includes a drive pulley and a driven pulley connected by a belt. The central shaft of the drive pulley is connected to the output shaft of the first motor. A transmission shaft is located at the center of the driven pulley. Three cams are mounted on the transmission shaft. The three cams are respectively located below the lower templates of the heat sealing mechanism, the punching mechanism, and the perforation mechanism, and cooperate with the free ends of push rods located on the bottom surface of the corresponding lower templates. The first electric motor is used to drive three cams to rotate simultaneously via belt drive, so that the corresponding push rods and cams make contact at different positions, thereby driving the corresponding lower template to move up and down.

5. The continuous coating apparatus for sustained-release tablets according to claim 1, characterized in that: The actuating mechanism includes an intermittent motion mechanism, the output end of which is connected to the side of the moving plate. A first pneumatic clamping mechanism is provided on the top surface of the moving plate. The first pneumatic clamping mechanism is used to clamp or release the upper coating, the lower coating, and the controlled-release tablets therein. The gap motion mechanism is used to drive the moving plate together with the first pneumatic clamping mechanism to move back and forth along the coating conveying direction to realize coating conveying.

6. The continuous coating apparatus for sustained-release tablets according to claim 5, characterized in that: The intermittent motion mechanism includes a second motor, the output shaft of which is connected to the center of the turntable. A limit pin is provided on the turntable, and the limit pin is engaged in an arc-shaped track groove. The arc-shaped track groove is formed on a synchronization plate. An extension rod is provided on each side of the synchronization plate, and the free end of each extension rod is engaged in a corresponding fixed slide groove. The synchronization plate is also connected to one end of a connecting rod, and the other end of the connecting rod is connected to a slider. The slider is mounted on a slide rail and is also connected to the side of a moving plate. The slide rail is arranged along the coating conveying direction. The first pneumatic clamping mechanism clamps the upper coating, the lower coating and the slow-release tablet therein. Then the second motor drives the turntable to rotate, so that the limit pin on the turntable moves along the arc-shaped track groove, thereby driving the synchronous plate and the slider to move along the coating conveying direction. In this way, the moving plate drives the first pneumatic clamping mechanism to move along the coating conveying direction, thereby realizing the coating conveying. The first pneumatic clamping mechanism releases the upper coating, lower coating, and the slow-release tablet therein. Then, the second motor drives the turntable to continue rotating, causing the limit pin on the turntable to continue moving along the arc-shaped track groove. This, along with the slider, drives the first pneumatic clamping mechanism on the moving plate to move in the opposite direction of the coating conveying direction and return to its original position.

7. The continuous coating apparatus for sustained-release tablets according to claim 5, characterized in that: A second pneumatic clamping mechanism is provided between the actuating mechanism and the punching mechanism. The second pneumatic clamping mechanism is used to clamp or release the upper coating, the lower coating and the controlled-release tablet therein.

8. The continuous coating apparatus for sustained-release tablets according to claim 1, characterized in that: The feeding mechanism includes an L-shaped cavity, inside which are three parallel feeding channels that together form a Y-shaped structure. Inside the horizontal part of the L-shaped cavity, a brush disc, a stop plate, and a pressing roller are arranged sequentially along the coating conveying direction. A gap is left between the bottom surface of each of them and the top surface of the lower coating. The center of the brush disc is connected to the output shaft of the reduction motor, which is used to drive the brush disc to rotate.

Citation Information

Patent Citations

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