A common optical path scanning imaging system

Abstract

The present invention provides a common optical path scanning imaging system, comprising: a light source module; a line beam conversion module, arranged in the direction of the light source module's outgoing light; a first beam splitter, arranged in the direction of the line beam conversion module's outgoing light; a reference arm module, arranged in the direction of the first reflected light output of the first beam splitter; a second beam splitter, arranged in the direction of the first beam splitter's outgoing light; a beam scanning module, arranged in the direction of the second beam splitter's outgoing light; a scanning objective lens module, arranged in the direction of the reflected light output of the beam scanning module, through which the light beam enters the human eye; a confocal detection module, arranged in the direction of the reflected light output of the second beam splitter, receiving the confocal scanning beam to generate a confocal scanning image; and a coherence tomography detection module, arranged in the direction of the second reflected light output of the first beam splitter, receiving a sample line beam and a reference line beam to generate an optical coherence tomography image. The present invention adopts a common optical path structure, has a simple system structure, and high imaging efficiency.

Description

Technical Field

[0001] The present invention relates to the technical field of optical imaging, and in particular to a common optical path scanning imaging system. Background Art

[0002] Fundus imaging technologies include confocal scanning imaging and optical coherence tomography. Each has its own advantages and disadvantages in terms of imaging speed, field of view, and imaging mode. For example, confocal scanning imaging offers high lateral resolution and a high signal-to-noise ratio, enabling fluorescence angiography, but its longitudinal resolution is insufficient. Optical coherence tomography offers deep imaging depth and high longitudinal resolution, but its lateral resolution is insufficient.

[0003] Currently, there are imaging systems that combine confocal scanning imaging with optical coherence tomography imaging. However, the existing combined imaging systems have complex structures and slow imaging speeds. Summary of the Invention

[0004] Therefore, the present invention aims to solve the technical problem of the complicated structure of the imaging system in the prior art, thereby providing a common optical path scanning imaging system.

[0005] According to a first aspect, an embodiment of the present invention provides a common optical path scanning imaging system, comprising:

[0006] Light source module, including optical coherence tomography light source and confocal scanning light source;

[0007] a line beam conversion module, disposed in the direction of the light output from the light source module, for converting a first parallel beam emitted by the light source module into a first line beam, and converting a second parallel beam emitted by the light source module into a second line beam; wherein the first parallel beam is a beam for coherent tomography, and the second parallel beam is a beam for confocal scanning imaging;

[0008] a first beam splitter, disposed in the outgoing light direction of the line beam conversion module, and configured to split the first line beam into a first sub-line beam and a second sub-line beam;

[0009] A reference arm module is provided in the first reflected light output direction of the first beam splitter, and is used to receive the first sub-line beam; the first sub-line beam passes through the reference arm module and outputs a reference line beam;

[0010] a second beam splitter, arranged in the direction of the outgoing light of the first beam splitter, and configured to transmit the second line beam and the second sub-line beam;

[0011] a beam scanning module, arranged in the direction of the outgoing light of the second beam splitter, for performing one-dimensional scanning on the second line beam and the second sub-line beam, wherein the beam scanning module adopts a scanning galvanometer;

[0012] a scanning objective lens module, arranged in the reflected light output direction of the light beam scanning module, so that the scanned second line beam and the second sub-line beam enter the human eye through the scanning objective lens module;

[0013] The sample line beam and the confocal scanning beam scattered by the human eye pass through the scanning objective lens module and the beam scanning module in sequence and reach the second beam splitter, wherein the sample line beam is the beam of the second sub-line beam scattered by the human eye, and the confocal scanning beam is the beam of the second line beam scattered by the human eye;

[0014] a confocal detection module, arranged in the direction of reflected light from the second beam splitter, wherein the confocal scanning beam is completely reflected by the second beam splitter, and the confocal detection module receives the reflected confocal scanning beam to generate a confocal scanning image;

[0015] The coherence tomography detection module is arranged in the second reflected light output direction of the first beam splitter. The first beam splitter is also used to reflect the sample line beam after passing through the second beam splitter. The coherence tomography detection module receives the reflected sample line beam and the reference line beam to generate optical coherence tomography imaging.

[0016] Optionally, the common optical path scanning imaging system further includes:

[0017] An annular light source, the illumination direction of which is opposite to the pupil of the human eye, wherein the first light beam emitted by the annular light source is reflected by the pupil of the human eye, passes through the hollow portion of the annular light source, and is transmitted to the scanning objective lens module;

[0018] a third beam splitter, disposed in the reflected light direction of the scanning objective lens module, and configured to split the first light beam after being reflected by the scanning objective lens module;

[0019] a first lens, arranged in the direction of the outgoing light of the third beam splitter, for transmitting the first light beam after the beam splitting;

[0020] The first photodetector is arranged at the focal position of the first lens and is used to generate pupil imaging.

[0021] Optionally, the common optical path scanning imaging system further includes:

[0022] The sight mark unit includes at least one lamp bead;

[0023] a second lens, disposed between the third beam splitter and the sight mark unit;

[0024] The light beam emitted by the lamp bead is transmitted to the third beam splitter through the second lens, is reflected by the third beam splitter and the scanning objective lens module in sequence, passes through the hollow part of the annular light source, and enters the human eye.

[0025] Optionally, the common optical path scanning imaging system further includes:

[0026] a relay lens group, arranged between the second beam splitter and the beam scanning module;

[0027] The second line beam and the second sub-line beam transmitted through the second beam splitter are transmitted to the beam scanning module through the relay lens group; the sample line beam and the confocal scanning beam passed through the beam scanning module are transmitted to the second beam splitter through the relay lens group.

[0028] Optionally, the light source module further includes:

[0029] a first collimator, arranged in the emission direction of the optical coherence tomography light source, and used for converting the light beam emitted by the optical coherence tomography light source into a first parallel light beam;

[0030] a second collimator, arranged in the emission direction of the confocal scanning light source, for converting the light beam emitted by the confocal scanning light source into a second parallel light beam;

[0031] A fourth beam splitter is provided in the direction of the outgoing light of the first collimator and the second collimator, and is used for splitting the first parallel light beam and the second parallel light beam, and transmitting the beams to the line beam conversion module.

[0032] Optionally, the coherence tomography detection module includes:

[0033] a third lens, arranged in the direction of the second reflected light of the first beam splitter;

[0034] a first aperture, arranged in the direction of the outgoing light of the third lens;

[0035] The second photodetector is arranged in the direction of the outgoing light of the first aperture; after the reference line beam and the sample line beam are split and reflected by the first beam splitter, they pass through the third lens and the first aperture in sequence and enter the second photodetector.

[0036] Optionally, the coherence tomography detection module further includes:

[0037] a grating, arranged in the direction of the outgoing light of the first aperture;

[0038] A fourth lens is arranged in the direction of the outgoing light of the grating;

[0039] After passing through the first aperture, the reference line beam and the sample line beam sequentially pass through the grating and the fourth lens and enter the second photodetector.

[0040] Optionally, the confocal detection module includes:

[0041] a fifth lens, arranged in the direction of the reflected light from the second beam splitter;

[0042] a filter, arranged in the direction of the outgoing light of the fifth lens;

[0043] a second aperture, arranged in the direction of the outgoing light of the filter;

[0044] a linear array photoelectric detector, arranged in the direction of the outgoing light of the second aperture;

[0045] After being split and reflected by the second beam splitter, the confocal scanning light beam passes through the fifth lens, the filter, and the second aperture in sequence and enters the linear array photodetector.

[0046] Optionally, the scanning objective lens module includes:

[0047] A sixth lens is arranged in the direction of the reflected light of the light beam scanning module;

[0048] a fifth beam splitter, arranged in the direction of the outgoing light of the sixth lens;

[0049] a seventh lens, arranged in the direction of the outgoing light of the fifth beam splitter;

[0050] The scanned second line beam and the second sub-line beam pass through the sixth lens, the fifth beam splitter, and the seventh lens in sequence and enter the human eye.

[0051] Optionally, the reference arm module includes:

[0052] A cylindrical lens is arranged in the first reflected light output direction of the first beam splitter;

[0053] a dispersion compensator, arranged in the direction of the outgoing light of the cylindrical lens;

[0054] A reference reflector, arranged in the direction of the outgoing light of the dispersion compensator;

[0055] The first sub-line beam passes through the cylindrical lens and the dispersion compensator in sequence and enters the reference reflector; the reference line beam reflected by the reference reflector passes through the dispersion compensator and the cylindrical lens in sequence and enters the coherence tomography detection module.

[0056] The technical solution of the present invention has the following advantages:

[0057] The common optical path scanning imaging system provided in embodiments of the present invention can simultaneously achieve optical coherence tomography and confocal scanning imaging. This not only combines optical coherence tomography and confocal scanning imaging technologies, but also utilizes a common optical path architecture, resulting in a simpler system structure and more convenient control. Furthermore, a single scan of the scanning objective lens module can simultaneously acquire confocal scanning and optical coherence tomography images of the retinal fundus. Both images have the same imaging magnification and imaging position, and the imaging speed is fast. BRIEF DESCRIPTION OF THE DRAWINGS

[0058] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the specific embodiments or the description of the prior art. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0059] Figure 1 This is a structural block diagram of a specific example of a common optical path scanning imaging system in Example 1 of the present application;

[0060] Figure 2 This is a structural diagram of a specific example of the common optical path scanning imaging system in Example 1 of the present application;

[0061] Figure 3 This is a structural diagram of another specific example of the common optical path scanning imaging system in Example 1 of the present application;

[0062] Explanation of the reference numerals: 1-light source module, 101-optical coherence tomography light source, 102-first collimator, 111-confocal scanning light source, 112-second collimator, 13-fourth beam splitter, 21-line beam conversion module, 22-first beam splitter, 23-second beam splitter, 24-relay lens group, 3-beam scanning module, 4-scanning objective lens module, 40-fifth beam splitter, 41-sixth lens, 42-seventh lens, 5-human eye, 6-reference arm module, 61-cylindrical lens, 62-dispersion compensation lens Compensator, 63-reference reflector, 7-coherence tomography detection module, 71-third lens, 72-first aperture, 73-second photodetector, 74-fourth lens, 75-grating, 8-confocal detection module, 81-fifth lens, 82-filter, 83-second aperture, 84-linear array photodetector, 9-visual target and pupil monitoring module, 91-third spectrometer, 901-annular light source, 902-first lens, 903-first photodetector, 911-second lens, 912-visual target unit. DETAILED DESCRIPTION

[0063] The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the embodiments described are only some embodiments of the present invention, not all embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making any creative efforts shall fall within the scope of protection of the present invention.

[0064] In the description of the present invention, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings and are intended solely to facilitate and simplify the description of the present invention. They are not intended to indicate or imply that the devices or components referred to must have, be constructed, or operate in a specific orientation, and therefore should not be construed as limitations on the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0065] In the description of the present invention, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections or electrical connections; direct connections or indirect connections through an intermediate medium; internal connections between two components; wireless connections or wired connections. Those skilled in the art will understand the specific meanings of the above terms in the present invention based on specific circumstances.

[0066] In addition, the technical features involved in the different embodiments of the present invention described below can be combined with each other as long as they do not conflict with each other.

[0067] Example 1

[0068] This embodiment provides a common optical path scanning imaging system, such as Figure 1 As shown, it includes: a light source module 1, a line beam transformation module 21, a beam scanning module 3, a scanning objective lens module 4, a reference arm module 6, a coherent tomography detection module 7, a confocal detection module 8, a first spectroscope 22 and a second spectroscope 23, as follows.

[0069] The light source module 1 includes an optical coherence tomography light source 101 and a confocal scanning light source 111 .

[0070] The line beam conversion module 21 is disposed in the direction of the light output from the light source module 1 and is used to convert the first parallel beam emitted by the light source module 1 into a first line beam, and the second parallel beam emitted by the light source module 1 into a second line beam. The first parallel beam is used for coherence tomography, and the second parallel beam is used for confocal scanning imaging. The line beam conversion module 21 can include a cylindrical lens, a combination of multiple cylindrical lenses, a combination of a cylindrical lens and a grating, or a combination of a cylindrical lens and a Powell prism.

[0071] The first beam splitter 22 is disposed in the outgoing light direction of the line beam conversion module 21 and is used to split the first line beam into a first sub-line beam and a second sub-line beam.

[0072] The reference arm module 6 is arranged in the first reflected light output direction of the first beam splitter 22 and is used to receive the first sub-line beam; the first sub-line beam passes through the reference arm module 6 to output a reference line beam.

[0073] The second beam splitter 23 is disposed in the direction of the outgoing light of the first beam splitter 22 and is used for transmitting the second linear beam and the second sub-linear beam.

[0074] The beam scanning module 3 is disposed in the direction of the output light from the second beam splitter 23 and is used to perform one-dimensional scanning of the second line beam and the second sub-line beam. In this embodiment, the beam scanning module 3 can include only one scanning galvanometer mirror, which can achieve one-dimensional scanning of the line beam on the fundus, with the scanning direction perpendicular to the length of the line beam, thereby illuminating a rectangular area of ​​the fundus. The beam scanning module 3 also simultaneously outputs a position signal of the one-dimensional scanning.

[0075] The scanning objective lens module 4 is arranged in the direction of the reflected light from the beam scanning module 3. The scanned second line beam and the second sub-line beam enter the human eye 5 through the scanning objective lens module 4. A rectangular illumination area can be formed at the fundus of the human eye 5 through the scanning objective lens module 4.

[0076] The sample line beam and the confocal scanning beam scattered by the human eye 5 pass through the scanning objective lens module 4 and the beam scanning module 3 in sequence and reach the second beam splitter 23, wherein the sample line beam is the beam of the second sub-line beam scattered by the human eye 5, and the confocal scanning beam is the beam of the second line beam scattered by the human eye 5.

[0077] The confocal detection module 8 is positioned in the direction of the reflected light from the second beam splitter 23. The confocal scanning beam is completely reflected by the second beam splitter 23. The confocal detection module 8 receives the reflected confocal scanning beam and generates a confocal scanning image. In this embodiment, the confocal scanning line beam returned from the fundus is received and synchronously processed with the position signal from the beam scanning module 3 to obtain a confocal scanning image of the fundus.

[0078] The coherence tomography detection module 7 is positioned in the second reflected light output direction of the first beam splitter 22. The first beam splitter 22 is also configured to reflect the sample line beam after it has been transmitted through the second beam splitter 23. The coherence tomography detection module 7 receives the reflected sample line beam and the reference line beam to generate an optical coherence tomography image. In this embodiment, the coherence tomography detection module 7 receives the reference line beam returned from the reference arm module 6 and the sample line beam returned from the fundus, achieving interference between the reference line beam and the sample line beam. After synchronous processing with the position signal from the beam scanning module 3, an optical coherence tomography image of the fundus is acquired.

[0079] In this embodiment, the specific optical path is: after the light source emitted by the optical coherence tomography light source 101 is converted into a first parallel beam, it is converted into a first line beam through the line beam conversion module 21; after the light source emitted by the confocal scanning light source 111 is converted into a second parallel beam, it is converted into a second line beam through the line beam conversion module 21; after the first line beam is split by the first beam splitter 22, part of the line beam (first sub-line beam) is reflected to the reference arm module 6, and the reference line beam is output to the coherence tomography detection module 7 through the reference arm module 6; the remaining part of the first line beam (second sub-line beam) and the second line beam are all transmitted through the first beam splitter 22, and pass through the second beam splitter 23, the beam scanning module 3, and the scanning objective lens module 4 in turn to enter the human eye 5, and the second sub-line beam and the second line beam are focused onto a line on the fundus retina through the optical system of the human eye 5 to scan the fundus retina of the human eye 5.

[0080] The sample line beam and the confocal scanning beam scattered by the human eye 5 return along the original path and pass through the scanning objective lens module 4, the beam scanning module 3, and the second beam splitter 23 in sequence. The confocal scanning beam is completely reflected by the second beam splitter 23 and enters the confocal detection module 8. The beam scanning module 3 simultaneously outputs a scanning position signal, which is synchronized with the confocal scanning beam signal obtained by the confocal detection module 8 to generate a confocal scanning imaging image; the sample line beam is completely transmitted through the second beam splitter 23 and propagates to the first beam splitter 22, and the sample line beam is completely reflected by the first beam splitter 22 to enter the coherence tomography detection module 7; the reference line beam and the sample line beam interfere with each other in the coherence tomography detection module 7, and the beam scanning module 3 simultaneously outputs a scanning position signal, which is synchronized with the interference signal of the coherence tomography detection module 7 to generate an optical coherence tomography imaging image.

[0081] In this embodiment, a common optical path structure is adopted, that is, the optical path after emission from the light source module 1 and the optical path after scattering by the human eye 5 can be shared, thereby simplifying the system structure and improving imaging efficiency. Specifically, when the optical coherence tomography light source 101 and the confocal scanning light source 111 are emitted simultaneously in the light source module 1, the light beam used for coherence tomography imaging and the light beam used for confocal scanning imaging can be transmitted to the human eye 5 through the common optical path composed of the line beam conversion module 21, the first beam splitter 22, the second beam splitter 23, the beam scanning module 3 and the scanning objective lens module 4. The sample line beam and the confocal scanning beam scattered by the human eye can be transmitted to the corresponding detection module through the common optical path composed of the second beam splitter 23, the beam scanning module 3 and the scanning objective lens module 4, thereby generating a corresponding imaging image.

[0082] The common optical path scanning imaging system provided in this embodiment can simultaneously achieve optical coherence tomography and confocal scanning imaging. Not only does it combine optical coherence tomography and confocal scanning imaging technologies, but its common optical path architecture also simplifies the system structure and makes control more convenient. Furthermore, a single scan of the scanning objective lens module can simultaneously acquire confocal scanning images and optical coherence tomography images of the retinal fundus. Both images have the same imaging magnification and imaging position, and the imaging speed is fast.

[0083] like Figure 2 As shown in FIG3 , as an optional embodiment, in an embodiment of the present invention, the common optical path scanning imaging system further includes: a sight mark and pupil monitoring module 9, which includes:

[0084] The annular light source 901 is oriented toward the human eye pupil. A first light beam emitted by the annular light source 901 is reflected by the human eye pupil, passes through the hollow portion of the annular light source 901, and is transmitted to the scanning objective lens module 4. The annular light source 901 can utilize an annular LED array, which can include at least three LEDs arranged evenly spaced in a circular pattern. The LEDs in the annular LED array can be selected to emit a characteristic wavelength above 1000 nm, with a typical wavelength being 1310 nm. In this embodiment, the aperture of the hollow portion is no smaller than the aperture of the light beam output by the scanning objective lens module 4.

[0085] The third beam splitter 91 is disposed in the reflected light output direction of the scanning objective lens module 4 , and is used to split the first light beam reflected by the scanning objective lens module 4 .

[0086] The first lens 902 is arranged in the outgoing light direction of the third beam splitter 91 and is used to transmit the first light beam after the beam splitting.

[0087] The first photodetector 903 is disposed at the focal position of the first lens 902 and is used to generate pupil imaging.

[0088] The first light beam emitted by the annular light source 901 is reflected by the pupil of the human eye, passes through the hollow part of the annular light source 901, and enters the third beam splitter 91 in the sight mark and pupil monitoring module 9 after being reflected by the scanning objective lens module 4. The light beam after being transmitted by the third beam splitter 91 is focused by the first lens 902 to the first photodetector 903. The first photodetector 903 converts the optical signal into an electrical signal to generate an imaging image of the pupil of the human eye 5.

[0089] When the common optical path scanning imaging system provided in the embodiment of the present invention is working, the subject can place his head on a head support, which has a three-dimensional translation adjustment function. It can be manually adjusted through a guide rail, or it can be configured as a motor-driven guide rail, which is controlled by the common optical path scanning imaging system or other electrical or communication connection system to realize electric adjustment of the head support, so that the pupil is imaged in the middle area of ​​the field of view, which is convenient for generating a pupil imaging image of the human eye 5.

[0090] like Figure 2 As shown in FIG3 , as an optional embodiment, in the embodiment of the present invention, the sight mark and pupil monitoring module 9 in the common optical path scanning imaging system further includes:

[0091] The sight mark unit 912 includes at least one lamp bead;

[0092] The second lens 911 is disposed between the third beam splitter 91 and the sight mark unit 912;

[0093] The light beam emitted by the lamp bead is transmitted to the third beam splitter 91 through the second lens 911, and is reflected by the third beam splitter 91 and the scanning objective lens module 4 in sequence, passes through the hollow part of the annular light source 901, and enters the human eye.

[0094] The sight mark and pupil monitoring module 9 can also generate a sight mark dot matrix beam through the sight mark unit 912 and the second lens 911 to achieve fixation or visual field guidance of the human eye. When at least one lamp bead in the sight mark unit 912 is illuminated, the light beam emitted by the lamp bead is transmitted through the second lens 911 to the third beam splitter 91. After being split and reflected by the third beam splitter 91 and the fifth beam splitter 40 in the scanning objective lens module 4, it passes through the hollow portion of the annular light source 901 and enters the human eye 5. The human eye 5 focuses on the illuminated lamp bead, thereby achieving fixation. When the sight mark unit 912 includes multiple lamp beads, by illuminating the lamp beads at different positions on the sight mark unit 912, different areas of the fundus retina of the human eye 5 will be guided to become optical coherence tomography imaging areas and confocal scanning imaging, thereby achieving functions such as auxiliary imaging alignment.

[0095] The sight mark units 912 can be light-emitting lamps arranged in an array with equal spacing. Typical arrangements include 3×3, 4×4, etc. The selected wavelength is a characteristic wavelength in the visible light band and has a bandwidth difference of at least 50nm from the wavelength included in the light source module 1. In this embodiment, the wavelength of the sight mark units 912 is preferably 550nm.

[0096] like Figure 2 As shown in FIG3 , as an optional implementation manner, in an embodiment of the present invention, the common optical path scanning imaging system further includes:

[0097] The relay lens group 24 is disposed between the second beam splitter 23 and the beam scanning module 3 to achieve relay propagation of the second line beam and the second sub-line beam.

[0098] The second line beam and the second sub-line beam transmitted through the second beam splitter 23 are transmitted to the beam scanning module 3 through the relay lens group 24; the sample line beam and the confocal scanning beam passed through the beam scanning module 3 are transmitted to the second beam splitter 23 through the relay lens group 24.

[0099] like Figure 2 As shown in FIG3 , as an optional implementation manner, in the embodiment of the present invention, the light source module 1 further includes:

[0100] A first collimator 102 is provided in the emission direction of the optical coherence tomography light source 101 and is used to convert the light beam emitted by the optical coherence tomography light source 101 into a first parallel light beam;

[0101] The second collimator 112 is arranged in the emission direction of the confocal scanning light source 111 and is used to convert the light beam emitted by the confocal scanning light source 111 into a second parallel light beam. The first collimator 102 and the second collimator 112 can be a transmission collimator or a reflection collimator.

[0102] The fourth beam splitter 13 is disposed in the direction of the output light from the first collimator 102 and the second collimator 112, and is used to split the first parallel light beam and the second parallel light beam, and transmit them to the line beam conversion module 21. The fourth beam splitter 13 can be a dichroic beam splitter, which is used to output parallel light after coupling and enter the line beam conversion module 21.

[0103] The light beam emitted by the optical coherence tomography light source 101 is converted into a first parallel light beam through the first collimator 102. The light beam emitted by the confocal scanning light source 111 is converted into a second parallel light beam through the second collimator 112. The first and second parallel light beams are transmitted to the line beam conversion module 21 through the fourth beam splitter 13. The line beam conversion module 21 then converts the first parallel light beam emitted by the light source module 1 into a first line beam and the second parallel light beam into a second line beam.

[0104] In this embodiment, when the optical coherence tomography is swept-source optical coherence tomography, the optical coherence tomography light source 101 can be a swept-source laser with a central wavelength of 840 nm or 1060 nm; the confocal scanning light source 111 can be a laser that outputs multiple characteristic wavelengths between 400 nm and 900 nm, or a combination of lasers with multiple characteristic wavelengths between 400 nm and 900 nm. When the optical coherence tomography is spectral-domain optical coherence tomography, the optical coherence tomography light source 101 can be a broadband laser with a central wavelength of approximately 840 nm; the confocal scanning light source 111 can be a laser that outputs multiple characteristic wavelengths between 400 nm and 900 nm, or a combination of lasers with multiple characteristic wavelengths between 400 nm and 900 nm.

[0105] In this embodiment, the light beam emitted by the optical coherence tomography light source 101 and the light beam emitted by the confocal scanning light source 111 are both converted into linear light beams through the line beam conversion module 21. Only one scanning galvanometer is used in the light beam scanning module 3, and a single scan can simultaneously obtain a confocal scanning imaging image and an optical coherence tomography imaging image of the fundus retina.

[0106] like Figure 2 As shown, when the optical coherence tomography is swept-source optical coherence tomography, as an optional implementation, in an embodiment of the present invention, the coherence tomography detection module 7 includes:

[0107] A third lens 71 is arranged in the second reflected light direction of the first beam splitter 22;

[0108] A first aperture 72 is provided in the direction of the outgoing light of the third lens 71;

[0109] A second photodetector 73 is disposed in the direction of the outgoing light from the first aperture 72. After being coupled, split, and reflected by the first beam splitter 22, the reference line beam and the sample line beam sequentially pass through the third lens 71 and the first aperture 72 before entering the second photodetector 73. The second photodetector 73 can be either a linear array photodetector or a planar array photodetector.

[0110] like Figure 3 As shown, when the optical coherence tomography is spectral domain optical coherence tomography, as an optional implementation, in an embodiment of the present invention, the coherence tomography detection module 7 further includes:

[0111] A grating 75 is provided in the direction of the light emitted from the first aperture 72;

[0112] A fourth lens 74 is arranged in the direction of the outgoing light of the grating 75;

[0113] After passing through the first aperture 72 , the reference line beam and the sample line beam sequentially pass through the grating 75 and the fourth lens 74 and enter the second photodetector 73 .

[0114] In this embodiment, the grating 75 can separate the light spectrums in the reference line beam and the sample line beam, and focus the light signals after passing through the fourth lens 74 to reach the second photodetector 73, which further converts the light signals into electrical signals. The second photodetector 73 is preferably a planar array photodetector.

[0115] like Figure 2 As shown in FIG3 , as an optional implementation manner, in an embodiment of the present invention, the confocal detection module 8 includes:

[0116] A fifth lens 81 is arranged in the direction of the reflected light from the second beam splitter 23;

[0117] The filter 82 is arranged in the direction of the outgoing light of the fifth lens 81;

[0118] A second aperture 83 is provided in the direction of the light emitted by the filter 82;

[0119] A linear array photodetector 84 is arranged in the direction of the outgoing light of the second aperture 83;

[0120] After being reflected by the second beam splitter 23, the confocal scanning light beam passes through the fifth lens 81, the filter 82, and the second aperture 83 in sequence and enters the linear array photodetector 84. The linear array photodetector 84 further converts the optical signal of the acquired confocal scanning light beam into an electrical signal.

[0121] In this embodiment, when the light source module 1 includes confocal scanning beams of multiple wavelengths, different characteristic wavelengths are turned on. By setting the filters included in the confocal detection module 8, different confocal scanning imaging functions can be achieved, including structural imaging, indocyanine green contrast imaging, autofluorescence imaging, sodium fluorescein contrast imaging, etc.

[0122] As an optional implementation, in an embodiment of the present invention, the scanning objective lens module 4 includes:

[0123] A sixth lens 41 is arranged in the direction of the reflected light from the light beam scanning module 3;

[0124] A fifth beam splitter 40 is arranged in the direction of the outgoing light of the sixth lens 41;

[0125] A seventh lens 42 is provided in the direction of the outgoing light of the fifth beam splitter 40;

[0126] After scanning, the second linear beam and the second sub-linear beam sequentially pass through the sixth lens 41, the fifth beam splitter 40, and the seventh lens 42 and enter the human eye. The beam scanning module 3 and the scanning objective lens module 4 form a rectangular area at the fundus of the human eye 5, thereby completely scanning the retina of the human eye 5 and acquiring a confocal scanning image and an optical coherence tomography image of the retina.

[0127] As an optional embodiment, in the embodiment of the present invention, the light beam scanning module 3 uses a scanning galvanometer. In one scan, a confocal scanning image and an optical coherence tomography image of the fundus retina can be simultaneously acquired, which has a simple structure and a fast imaging speed.

[0128] As an optional implementation manner, in the embodiment of the present invention, the reference arm module 6 further includes: a cylindrical lens 61 , a dispersion compensator 62 , and a reference reflector 63 .

[0129] A cylindrical lens 61 is arranged in the first reflected light direction of the first beam splitter 22;

[0130] The dispersion compensator 62 is arranged in the direction of the outgoing light of the cylindrical lens 61;

[0131] A reference reflector 63 is provided in the direction of the outgoing light of the dispersion compensator 62;

[0132] After the first line light beam is split by the first beam splitter 22, the first sub-line light beam passes through the cylindrical lens 61 and the dispersion compensator 62 in sequence and enters the reference reflector 63. The reference reflector 63 can be displaced along the optical axis. The reference line light beam reflected by the reference reflector 63 passes through the dispersion compensator 62 and the cylindrical lens 61 in sequence and enters the coherence tomography detection module 7, so as to achieve optical path matching between the reference line light beam output by the reference arm module 6 and the sample line light beam, thereby ensuring that the optical path difference between the reference line light beam and the sample line light beam is within the coherence length of the optical coherence tomography light source 101.

[0133] The dispersion compensator 62 may include a dispersion compensating prism, a corner cube, an aperture, or a combination of these components to compensate for dispersion, balance the physical dispersion of the system, and improve axial resolution. The reference mirror 63 may be a single plane mirror or a combination of multiple plane mirrors.

[0134] In this embodiment, a portion of the line beam (first sub-line beam) split by the first beam splitter 22 enters the reference arm module 6. The reference arm module 6 performs optical path compensation and dispersion compensation on the first sub-line beam. The output reference line beam can match the optical path of the sample line beam, thereby satisfying the interference condition and realizing an optical coherence tomography image.

[0135] Obviously, the above embodiments are merely examples for clarity of explanation and are not intended to limit the implementation methods. Those skilled in the art will readily appreciate that other variations or modifications based on the above descriptions are possible. It is not necessary and impossible to enumerate all implementation methods here. Obvious variations or modifications arising therefrom remain within the scope of protection of the present invention.

Claims

1. A common optical path scanning imaging system, characterized in that: include: A light source module (1) includes an optical coherence tomography light source (101) and a confocal scanning light source (111); A line beam conversion module (21) is arranged in the direction of the light output of the light source module (1), and is used to convert a first parallel light beam emitted by the light source module (1) into a first line beam, and to convert a second parallel light beam emitted by the light source module (1) into a second line beam; wherein the first parallel light beam is a light beam used for coherent tomography imaging, and the second parallel light beam is a light beam used for confocal scanning imaging; a first beam splitter (22), arranged in the direction of the outgoing light of the line beam conversion module (21), and used for splitting the first line beam into a first sub-line beam and a second sub-line beam; A reference arm module (6) is arranged in the first reflected light output direction of the first beam splitter (22) and is used to receive the first sub-line light beam; the first sub-line light beam passes through the reference arm module (6) to output a reference line light beam; a second beam splitter (23), arranged in the direction of the outgoing light of the first beam splitter (22), and used for transmitting the second line light beam and the second sub-line light beam; a light beam scanning module (3), arranged in the direction of the outgoing light of the second beam splitter (23), and used for performing one-dimensional scanning on the second line light beam and the second sub-line light beam, wherein the light beam scanning module (3) uses a scanning galvanometer; A scanning objective lens module (4) is arranged in the reflected light output direction of the light beam scanning module (3), and the scanned second line light beam and the second sub-line light beam enter the human eye through the scanning objective lens module (4); The sample line beam and the confocal scanning beam scattered by the human eye pass through the scanning objective lens module (4) and the beam scanning module (3) in sequence and reach the second beam splitter (23), wherein the sample line beam is the beam of the second sub-line beam scattered by the human eye, and the confocal scanning beam is the beam of the second line beam scattered by the human eye; A confocal detection module (8) is arranged in the direction of the reflected light of the second beam splitter (23), the confocal scanning light beam is completely reflected by the second beam splitter (23), and the confocal detection module (8) receives the reflected confocal scanning light beam to generate a confocal scanning image; A coherence tomography detection module (7) is arranged in the second reflected light output direction of the first beam splitter (22); the first beam splitter (22) is further used to reflect the sample line beam after being transmitted through the second beam splitter (23); the coherence tomography detection module (7) receives the reflected sample line beam and the reference line beam to generate optical coherence tomography imaging.

2. The common optical path scanning imaging system according to claim 1, characterized in that: Also includes: An annular light source (901) has an irradiation direction opposite to the pupil of a human eye, wherein a first light beam emitted by the annular light source (901) is reflected by the pupil of the human eye, passes through a hollow portion of the annular light source (901), and is transmitted to the scanning objective lens module (4); a third beam splitter (91), arranged in the reflected light direction of the scanning objective lens module (4), and used for splitting the first light beam after being reflected by the scanning objective lens module (4); a first lens (902), arranged in the direction of the outgoing light of the third beam splitter (91), and configured to transmit the first light beam after the beam splitting; A first photodetector (903) is arranged at the focal position of the first lens (902) and is used to generate pupil imaging.

3. The common optical path scanning imaging system according to claim 2, characterized in that: Also includes: The sight mark unit (912) includes at least one lamp bead; a second lens (911) disposed between the third beam splitter (91) and the sight mark unit (912); The light beam emitted by the lamp bead is transmitted through the second lens (911) to the third beam splitter (91), is reflected by the third beam splitter (91) and the scanning objective lens module (4) in sequence, passes through the hollow part of the annular light source (901), and enters the human eye.

4. The common optical path scanning imaging system according to claim 1, characterized in that: Also includes: a relay lens group (24) disposed between the second beam splitter (23) and the light beam scanning module (3); The second line beam and the second sub-line beam transmitted through the second beam splitter (23) are transmitted to the beam scanning module (3) through the relay lens group (24); the sample line beam and the confocal scanning beam passed through the beam scanning module (3) are transmitted to the second beam splitter (23) through the relay lens group (24).

5. The common optical path scanning imaging system according to claim 1, characterized in that: The light source module (1) further comprises: A first collimator (102) is arranged in the emission direction of the optical coherence tomography light source (101) and is used to convert the light beam emitted by the optical coherence tomography light source (101) into a first parallel light beam; a second collimator (112), arranged in the emission direction of the confocal scanning light source (111), and used for converting the light beam emitted by the confocal scanning light source (111) into a second parallel light beam; A fourth beam splitter (13) is arranged in the direction of the outgoing light of the first collimator (102) and the second collimator (112), and is used to split the first parallel light beam and the second parallel light beam, and transmit them to the line beam conversion module (21).

6. The common optical path scanning imaging system according to claim 1, characterized in that: The coherence chromatography detection module (7) comprises: a third lens (71), arranged in the second reflected light output direction of the first beam splitter (22); a first aperture (72) arranged in the direction of the light emitted by the third lens (71); A second photodetector (73) is arranged in the direction of the outgoing light of the first aperture (72); after the reference line beam and the sample line beam are split and reflected by the first beam splitter (22), they pass through the third lens (71) and the first aperture (72) in sequence and enter the second photodetector (73).

7. The common optical path scanning imaging system according to claim 6, characterized in that: The coherence chromatography detection module (7) further comprises: a grating (75) arranged in the direction of the light emitted from the first aperture (72); a fourth lens (74), arranged in the direction of the outgoing light of the grating (75); After passing through the first aperture (72), the reference line beam and the sample line beam sequentially pass through the grating (75) and the fourth lens (74) and enter the second photodetector (73).

8. The common optical path scanning imaging system according to claim 1, characterized in that: The confocal detection module (8) comprises: A fifth lens (81) is arranged in the direction of light reflected from the second beam splitter (23); a filter (82) arranged in the direction of the light emitted by the fifth lens (81); a second aperture (83) arranged in the direction of light emitted from the filter (82); a linear array photoelectric detector (84), arranged in the direction of the light emitted by the second aperture (83); After being split and reflected by the second beam splitter (23), the confocal scanning light beam passes through the fifth lens (81), the filter (82), and the second aperture (83) in sequence and enters the linear array photodetector (84).

9. The common optical path scanning imaging system according to claim 1, characterized in that: The scanning objective lens module (4) comprises: a sixth lens (41), arranged in the direction of light reflected from the light beam scanning module (3); a fifth beam splitter (40), arranged in the direction of the outgoing light of the sixth lens (41); a seventh lens (42) arranged in the direction of the outgoing light of the fifth beam splitter (40); The scanned second line beam and the second sub-line beam pass through the sixth lens (41), the fifth beam splitter (40), and the seventh lens (42) in sequence and enter the human eye.

10. The common optical path scanning imaging system according to any one of claims 1 to 9, characterized in that: The reference arm module (6) comprises: a cylindrical lens (61) arranged in the first reflected light output direction of the first beam splitter (22); a dispersion compensator (62) arranged in the direction of the outgoing light of the cylindrical lens (61); a reference reflector (63) arranged in the direction of the outgoing light of the dispersion compensator (62); The first sub-line light beam passes through the cylindrical lens (61) and the dispersion compensator (62) in sequence and enters the reference reflector (63); the reference line light beam reflected by the reference reflector (63) passes through the dispersion compensator (62) and the cylindrical lens (61) in sequence and enters the coherent tomography detection module (7).

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