Constant temperature incubation components, reagent card incubation mechanisms, and medical testing devices
By combining semiconductor cooling components and heat-conducting components on the incubation tray, the problem of uneven temperature in the incubation tray is solved, thereby improving detection accuracy and efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2022-12-14
- Publication Date
- 2026-03-10
AI Technical Summary
In existing technologies, uneven temperatures across different parts of the incubation tray affect detection accuracy and efficiency.
The incubation tray is combined with a semiconductor cooling device, and heat is transferred to the center or circumferential edge of the incubation tray through a heat-conducting component to ensure temperature uniformity.
This achieves temperature uniformity across all parts of the incubation tray, improving detection accuracy and efficiency.
Smart Images

Figure CN116125059B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of medical device technology, and in particular to a constant temperature incubation component, a reagent card incubation mechanism, and a medical testing device. Background Technology
[0002] In traditional techniques, reagent cards for immunofluorescence assays require incubation within a set temperature range to ensure uniform sample reaction. A common temperature control method involves placing the reagent cards in a circular or linear arrangement on the support surface of an incubation tray. A heating element / film contacts the tray to heat and control the temperature, ensuring the reagent cards reach the preset range. However, if the laboratory ambient temperature exceeds the maximum set temperature of the reagent cards (i.e., the cards are heated to ambient temperature), this method fails to provide effective temperature control. A few companies use thermoelectric semiconductor cooling pads (also known as Peltiers) directly attached to the incubation tray, enabling both heating and cooling. However, the temperature is not uniform across the incubation tray, resulting in uneven heating of the reagent cards above the tray, affecting detection accuracy and reducing efficiency. Summary of the Invention
[0003] Therefore, it is necessary to overcome the shortcomings of existing technologies and provide a constant temperature incubation component, reagent card incubation mechanism and medical testing device that can ensure the uniformity of temperature in all parts of the incubation tray in the circumferential direction, thereby ensuring detection accuracy and efficiency.
[0004] The technical solution is as follows: a constant temperature incubation component, the constant temperature incubation component comprising:
[0005] An incubation tray, the incubation tray having a top surface for supporting reagent cards and a bottom surface opposite to the top surface; and
[0006] A semiconductor cooling device is connected to the incubation tray and is used to transfer heat to the middle portion of the bottom surface, such that the heating time of the middle portion of the bottom surface is earlier than the heating time of the area outside the middle portion of the bottom surface; or, it is used to transfer heat to the circumferential edge portion of the bottom surface, such that the heating time of the circumferential edge portion of the bottom surface is earlier than the heating time of the area outside the circumferential edge portion of the bottom surface.
[0007] In one embodiment, the constant temperature incubation assembly further includes a first heat-conducting element disposed between the incubation tray and the semiconductor cooling element; the first heat-conducting element is connected to the semiconductor cooling element; the first heat-conducting element is also connected to the middle portion of the bottom surface, or the first heat-conducting element includes an annular connecting portion adapted to the circumferential edge portion of the bottom surface, the annular connecting portion being connected to the circumferential edge portion of the bottom surface.
[0008] In one embodiment, the first thermally conductive element includes an adhesive portion connected to the middle portion of the bottom surface and a thermally conductive portion connected to the adhesive portion. The thermally conductive portion is spaced from the bottom surface or connected by a low thermal conductivity material. The thermally conductive portion is connected to the semiconductor cooling element, which is located at the outer periphery of the bottom surface.
[0009] In one embodiment, the bottom surface is formed with a recess adapted to the first heat-conducting element, and the first heat-conducting element is disposed in the recess; the bottom wall of the recess is stepped and includes a first wall surface and a second wall surface connected to the first wall surface, the fitting part is fitted to the first wall surface, and the heat-conducting part is spaced from the second wall surface.
[0010] In one embodiment, the constant temperature incubation assembly further includes a heat insulation plate and a heat dissipation assembly; the heat insulation plate is in contact with the bottom surface of the incubation tray, and the heat insulation plate is provided with a first window corresponding to the position of the semiconductor cooling element, and the heat dissipation assembly passes through the first window and is connected to the semiconductor cooling element; the heat dissipation assembly includes a heat dissipation plate, a second heat-conducting element, heat dissipation fins, and a heat dissipation fan; the heat dissipation plate is connected to the heat dissipation fins through the second heat-conducting element, and the heat dissipation fan is connected to the heat dissipation fins.
[0011] A reagent card incubation mechanism includes the aforementioned constant temperature incubation component and a card dispensing turntable rotatably disposed on the incubation tray. The card dispensing turntable has multiple receiving slots adapted to the reagent card and is used to drive the reagent card to rotate.
[0012] In one embodiment, the opening of the receiving slot faces the top surface, which is a plane and abuts against the reagent card; and / or, the reagent card incubation mechanism further includes a heat preservation cover, which is connected to the incubation tray and covers the outside of the card dispensing turntable; and / or, the reagent card incubation mechanism further includes a driving mechanism, which is connected to the card dispensing turntable and is used to drive the card dispensing turntable to rotate.
[0013] In one embodiment, the card dial has a plurality of mating teeth on its circumferential outer edge; the drive mechanism includes a first motor and a gear coaxially connected to the shaft of the first motor; the mating teeth mesh with the gear.
[0014] In one embodiment, the reagent card incubation mechanism further includes an evaporation plate; a circumferentially arranged guide groove is formed on the outer periphery of the top surface, and the incubation plate is also provided with a guide hole communicating with the guide groove; the evaporation plate is located below the incubation plate and is used to receive condensate falling from the guide hole; and / or, the reagent card incubation mechanism further includes a card ejection assembly for ejecting the reagent card in the receiving groove along the radial direction of the incubation plate; the card ejection assembly includes a pushing mechanism and a pushing member connected to the pushing mechanism; the incubation plate is provided with a radially arranged movable opening, and the pushing member is movably disposed in the movable opening.
[0015] A medical testing device, the medical testing device including the reagent card incubation mechanism.
[0016] In use, the aforementioned constant-temperature incubation component, reagent card incubation mechanism, and medical testing device utilize a semiconductor cooling element to transfer heat / cold energy to the central part of the bottom surface. The heat / cold energy at the central part of the bottom surface then conducts outwards, ensuring the uniformity of the incubation area around the circumference of the incubation tray, thereby guaranteeing the detection accuracy and efficiency of the reagent card. Alternatively, the semiconductor cooling element can transfer heat / cold energy to the circumferential edge of the bottom surface, and the heat / cold energy at the circumferential edge of the bottom surface then conducts outwards towards the center, similarly ensuring the uniformity of the incubation area around the circumferential direction of the incubation tray, thus guaranteeing the detection accuracy and efficiency of the reagent card. Attached Figure Description
[0017] The accompanying drawings, which form part of this application, are used to provide a further understanding of this application. The illustrative embodiments of this application and their descriptions are used to explain this application and do not constitute an undue limitation of this application.
[0018] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.
[0019] Figure 1 This is a schematic diagram of the exploded structure of a constant temperature incubation component according to an embodiment of the present invention.
[0020] Figure 2 This is a schematic diagram of the exploded structure of a constant temperature incubation component according to an embodiment of the present invention from another perspective.
[0021] Figure 3 This is a schematic diagram of the structure of a constant temperature incubation component according to an embodiment of the present invention;
[0022] Figure 4This is an exploded structural diagram of a reagent card incubation mechanism according to an embodiment of the present invention;
[0023] Figure 5 This is a schematic diagram of the structure of a reagent card incubation mechanism according to an embodiment of the present invention;
[0024] Figure 6 This is a cross-sectional view of a reagent card incubation mechanism according to an embodiment of the present invention;
[0025] Figure 7 for Figure 6 A magnified structural diagram at point A;
[0026] Figure 8 This is a schematic diagram of the card dispensing component according to an embodiment of the present invention.
[0027] 10. Incubation tray; 11. Top surface; 12. Flow channel; 13. Flow hole; 14. Movable opening; 15. Edge guard; 151. Discharge port; 16. Recess; 161. First wall surface; 162. Second wall surface; 17. Insulation ring; 18. Fixing frame; 20. Semiconductor cooling component; 30. First heat conduction component; 31. Fitting part; 311. Clearance opening; 32. Heat conduction part; 40. Insulation plate; 41. First window; 42. Second window; 50. Heat dissipation assembly; 51. Heat dissipation plate; 52. 53. Second heat-conducting component; 54. Heat dissipation fins; 55. Heat dissipation fan; 60. Reagent card; 70. Card dispensing turntable; 71. Receiving slot; 72. Mating teeth; 80. Insulation cover; 91. Drive mechanism; 911. First motor; 912. Gear; 92. Evaporation plate; 93. Flow guide; 94. Card dispensing assembly; 941. Pushing mechanism; 9411. Support; 9412. Second motor; 9413. Drive wheel; 9414. Driven wheel; 9415. Transmission element; 942. Pushing component. Detailed Implementation
[0028] To make the above-mentioned objectives, features, and advantages of this application more apparent and understandable, the specific embodiments of this application are described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a thorough understanding of this application. However, this application can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this application. Therefore, this application is not limited to the specific embodiments disclosed below.
[0029] As described in the background art, there is a problem of uneven temperature in different parts of the incubation tray in the prior art. The inventors have found that the reason for this problem is that in the existing temperature control method of directly sticking Peltier to the incubation tray, the temperature of the part of the incubation tray facing the Peltier is greater than the temperature of the part of the incubation tray away from the Peltier.
[0030] Based on the above reasons, the present invention provides a constant temperature incubation component, a reagent card incubation mechanism, and a medical testing device, which can better control the temperature of various parts on the incubation tray and improve uniformity, thereby ensuring detection accuracy and efficiency.
[0031] See Figures 1 to 3 , Figure 1 This diagram shows an exploded view of the isothermal incubation assembly according to an embodiment of the present invention. Figure 2 This diagram shows another perspective view of the exploded structure of a constant temperature incubation component according to an embodiment of the present invention. Figure 3 A schematic diagram of a constant-temperature incubation assembly according to an embodiment of the present invention is shown. An embodiment of this application provides a constant-temperature incubation assembly comprising: an incubation tray 10 and a semiconductor cooling element 20. The incubation tray 10 has a top surface 11 for supporting a reagent card 60 and a bottom surface opposite to the top surface 11. The semiconductor cooling element 20 is connected to the incubation tray 10 and is used to transfer heat to the middle portion of the bottom surface, so that the heating time of the middle portion of the bottom surface is earlier than the heating time of the area outside the middle portion of the bottom surface; or, to transfer heat to the circumferential edge portion of the bottom surface, so that the heating time of the circumferential edge portion of the bottom surface is earlier than the heating time of the area outside the circumferential edge portion of the bottom surface.
[0032] In use, the aforementioned constant temperature incubation component allows the semiconductor cooling element 20 to transfer heat / cold energy to the central part of the bottom surface, and the heat / cold energy at the central part of the bottom surface is conducted to its surroundings, thereby ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and detection efficiency of the reagent card 60; alternatively, the semiconductor cooling element 20 transfers heat / cold energy to the circumferential edge of the bottom surface, and the heat / cold energy at the circumferential edge of the bottom surface is conducted to its center, similarly ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and detection efficiency of the reagent card 60.
[0033] Please see Figure 1 and Figure 2In one embodiment, the constant temperature incubation assembly further includes a first heat-conducting element 30 disposed between the incubation tray 10 and the semiconductor cooling element 20. The first heat-conducting element 30 is connected to the semiconductor cooling element 20. The first heat-conducting element 30 is also connected to the middle portion of the bottom surface. Thus, the semiconductor cooling element 20 transfers thermal / cold energy to the first heat-conducting element 30, which in turn transfers the thermal / cold energy to the middle portion of the bottom surface. From the middle portion of the bottom surface, the thermal / cold energy is conducted to the periphery of the bottom surface, thereby ensuring the uniformity of the incubation area of the incubation tray 10 in its circumferential direction. This is beneficial for the uniform heating of the multiple reagent cards 60 arranged circumferentially on the incubation tray 10. Furthermore, due to the presence of the first heat-conducting element 30, energy is transferred to the central part of the bottom surface of the incubation tray 10, making the placement of the semiconductor cooling element 20 more flexible and adjustable according to actual needs. This avoids some components located in the area below the central part of the bottom surface of the incubation tray 10 (such as the card dispensing assembly 94 used to push the reagent card 60 outward), and prevents interference with components in the area below the central part of the bottom surface.
[0034] In another embodiment, the constant temperature incubation assembly further includes a first heat-conducting element 30 disposed between the incubation tray 10 and the semiconductor cooling element 20. The first heat-conducting element 30 is connected to the semiconductor cooling element 20. The first heat-conducting element 30 includes an annular connecting portion adapted to the circumferential edge of the bottom surface, and the annular connecting portion is connected to the circumferential edge of the bottom surface. In this way, the semiconductor cooling element 20 transfers heat / cold energy to the first heat-conducting element 30, and the first heat-conducting element 30 transfers heat / cold energy to the circumferential edge of the bottom surface connected to it through the annular connecting portion, thereby enabling heat / cold energy to be conducted from the circumferential edge of the bottom surface to the center of the bottom surface, thereby ensuring the uniformity of the incubation area of the incubation tray 10 in its circumferential direction. Because of the first heat-conducting element 30, energy is transferred to the bottom circumferential edge of the incubation tray 10, making the placement of the semiconductor cooling element 20 more flexible and adjustable according to actual needs. Moreover, the semiconductor cooling element 20 does not need to be shaped to fit the bottom circumferential edge.
[0035] As some alternative solutions, the first heat-conducting component 30 can be omitted, and the semiconductor cooling component 20 can be directly connected to the middle part of the bottom surface or directly connected to the circumferential edge of the bottom surface.
[0036] Please see Figures 1 to 3In one embodiment, the first heat-conducting element 30 includes a bonding portion 31 connected to the center portion of the bottom surface and a heat-conducting portion 32 connected to the bonding portion 31. The heat-conducting portion 32 is spaced from the bottom surface or connected by a low thermal conductivity material, and the heat-conducting portion 32 is connected to the thermoelectric cooler 20. The thermoelectric cooler 20 is located at the outer periphery of the bottom surface. Specifically, the thermoelectric cooler 20 transfers heat / cold energy to the heat-conducting portion 32, which then transfers the heat / cold energy to the bonding portion 31, and finally, the bonding portion 31 transfers the heat / cold energy to the center portion of the bottom surface connected to it. Furthermore, since the thermoelectric cooler 20 is located at the outer periphery of the bottom surface, it avoids some components located in the area below the center portion of the bottom surface of the incubation tray 10, i.e., it does not interfere with components in the area below the center portion of the bottom surface. In addition, since the heat-conducting part 32 is spaced from the bottom surface or connected by a low thermal conductivity material, the air layer or low thermal conductivity material can slow down the speed at which the heat-conducting part 32 conducts energy to the incubation tray 10 above it. In this way, the heat / cold energy of the heat-conducting part 32 is mainly transferred to the bonding part 31.
[0037] It should be noted that low thermal conductivity materials refer to materials with a low thermal conductivity coefficient. The selection range includes thermal insulation materials or refractory materials, such as, but not limited to, at least one of aluminum silicate ceramics, chromium aluminum silicate ceramics, alumina ceramics, aerogel materials, polyurethane foam materials, etc.
[0038] In one embodiment, the first heat-conducting element 30 includes, but is not limited to, various high-efficiency heat-conducting materials such as copper, copper-aluminum alloy, and graphene film.
[0039] Please see Figures 1 to 3 In one embodiment, a recess 16 adapted to the first heat-conducting element 30 is formed on the bottom surface, and the first heat-conducting element 30 is disposed within the recess 16. In this way, the first heat-conducting element 30 is disposed within the recess 16 and will not protrude outside the recess 16, thereby ensuring that the bottom surface of the incubation tray 10 is flat. This makes the fabrication of the insulation layer on the bottom surface of the incubation tray 10 simple and provides good insulation effect.
[0040] Please see Figures 1 to 3 In one embodiment, the bottom wall of the recess 16 is stepped and includes a first wall surface 161 and a second wall surface 162 connected to the first wall surface 161. The fitting portion 31 is fitted to the first wall surface 161, and the heat-conducting portion 32 is spaced from the second wall surface 162. Thus, the first heat-conducting member 30 is configured as a flat plate, for example, and when the fitting portion 31 of the first heat-conducting member 30 is fitted to the first wall surface 161, the heat-conducting portion 32 naturally forms a gap with the second wall surface 162.
[0041] Of course, as some alternative solutions, it is not limited to setting the bottom wall of the recess 16 as stepped, but for example, setting the first heat-conducting element 30 as stepped, and setting the bottom wall of the recess 16 as flat, so that when the fitting part 31 and the bottom wall of the recess 16 are fitted together, the heat-conducting part 32 and the bottom wall of the recess 16 are spaced apart.
[0042] Please see Figure 4 , Figure 4 An exploded view of the reagent card incubation mechanism according to an embodiment of the present invention is shown. In one embodiment, the constant temperature incubation assembly further includes a heat preservation plate 40 and a heat dissipation assembly 50. The heat preservation plate 40 is in contact with the bottom surface of the incubation tray 10, and the heat preservation plate 40 is provided with a first window 41 corresponding to the position of the semiconductor cooling element 20. The heat dissipation assembly 50 passes through the first window 41 and is connected to the semiconductor cooling element 20. In this way, the heat preservation plate 40 provides heat preservation for the bottom surface of the incubation tray 10, preventing energy loss from the incubation tray 10 to the outside, thus providing good temperature control for the reagent card 60 located above its top surface 11. In addition, the semiconductor cooling element 20 is also connected to the heat dissipation assembly 50, which dissipates the (cold / hot) energy on the side of the semiconductor cooling element 20 facing away from the incubation tray 10 in a timely manner, thereby ensuring the working performance of the semiconductor cooling element 20.
[0043] Please see Figure 4 In one embodiment, the heat dissipation assembly 50 includes a heat sink 51, a second heat-conducting element 52, heat dissipation fins 53, and a cooling fan 54. The heat sink 51 is connected to the heat dissipation fins 53 via the second heat-conducting element 52, and the cooling fan 54 is connected to the heat dissipation fins 53. Thus, the (cold / hot) energy of the heat sink 51 is transferred to the heat dissipation fins 53 through the second heat-conducting element 52, and the cooling fan 54 dissipates the (cold / hot) energy outward from the heat dissipation fins 53 when it operates, resulting in good heat dissipation performance.
[0044] Optionally, the second heat-conducting element 52 may include, but is not limited to, a heat-conducting copper rod, a heat-conducting aluminum rod, or other metal rods, for example, one, two, three, or more. One end of the second heat-conducting element 52 is disposed through the heat sink 51, and the other end of the second heat-conducting element 52 is connected to the heat sink fins 53. The second heat-conducting element 52 not only transfers energy from the heat sink 51 to the heat sink fins 53, but also allows for flexible adjustment of its shape according to actual needs, enabling flexible arrangement of the heat sink fins 53 and the cooling fan 54 inside the chassis. Optionally, the shape of the second heat-conducting element 52 may include, but is not limited to, various regular or irregular shapes such as straight lines, L-shapes, and S-shapes. In this embodiment, the second heat-conducting element 52 is specifically configured as an L-shape.
[0045] Please see Figure 4In one embodiment, the constant temperature incubation assembly further includes a heat-insulating ring 17 surrounding the incubation tray 10. Thus, the heat-insulating ring 17 insulates the incubation tray 10 in the circumferential direction, preventing energy loss from the incubation tray 10 to the outside, thereby providing good temperature control for the reagent card 60 located above its top surface 11.
[0046] It should be noted that the incubation tray 10 includes, but is not limited to, regular or irregular shapes such as circular trays, elliptical plates, and polygonal trays. Polygonal trays include, but are not limited to, triangular trays, quadrilateral trays, pentagonal trays, etc. In this embodiment, the incubation tray 10 is specifically selected as a circular tray, and multiple reagent cards 60 are arranged sequentially and at intervals around the circumference of the incubation tray 10. This ensures the uniformity of the incubation area of the incubation tray 10 around its circumference, thereby ensuring the detection accuracy and efficiency of the reagent cards 60.
[0047] Please see Figures 1 to 3 In one embodiment, the constant temperature incubation assembly further includes a fixing frame 18 disposed on the bottom surface of the incubation tray 10. The fixing frame 18 spans the recess 16 and provides a certain degree of fixation for the first heat-conducting element 30 located in the recess 16. In addition, the semiconductor cooling element 20 is disposed inside the fixing frame 18, that is, the fixing frame 18 also provides a fixation for the semiconductor cooling element 20. Furthermore, the heat sink 51 is connected to the fixing frame 18, thereby ensuring a stable connection between the heat sink assembly 50 and the incubation tray 10, and thus ensuring the reliability of heat dissipation.
[0048] Please see Figure 4 In one embodiment, a reagent card incubation mechanism is provided. The reagent card incubation mechanism includes the constant temperature incubation component of any of the above embodiments. The reagent card incubation mechanism also includes a card dispensing turntable 70, which is rotatably disposed on the incubation tray 10. The card dispensing turntable 70 is provided with a plurality of receiving slots 71 adapted to the reagent card 60. The card dispensing turntable 70 is used to drive the reagent card 60 to rotate.
[0049] In the aforementioned reagent card incubation mechanism, during use, the semiconductor cooling element 20 transfers heat / cold energy to the central part of the bottom surface, and the heat / cold energy at the central part of the bottom surface is conducted to its surroundings, thereby ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and efficiency of the reagent card 60; alternatively, the semiconductor cooling element 20 transfers heat / cold energy to the circumferential edge of the bottom surface, and the heat / cold energy at the circumferential edge of the bottom surface is conducted to its center, similarly ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and efficiency of the reagent card 60. Furthermore, while the incubation tray 10 incubates each reagent card, each reagent card 60 rotates along the circumferential direction of the top surface 11 under the drive of the card dispensing turntable 70, sequentially operating between the card entry station, detection station, and card exit station, and working in a cyclical manner.
[0050] Please see Figure 4 In one embodiment, the opening of the receiving slot 71 faces the top surface 11, which is a plane and abuts against the reagent card 60. Thus, the incubation tray 10 can directly transfer heat / cold energy to the reagent card 60, resulting in better temperature control of the reagent card 60.
[0051] Please see Figure 4 and Figure 5 , Figure 5 A schematic diagram of a reagent card incubation mechanism according to an embodiment of the present invention is shown. In one embodiment, the reagent card incubation mechanism further includes a heat-insulating cover 80. The heat-insulating cover 80 is connected to the incubation tray 10 and covers the outside of the card dispensing turntable 70. Thus, the card dispensing turntable 70, like a cover, is placed above the incubation tray 10, forming a first layer of constant temperature protection; the heat-insulating cover 80 provides further heat preservation, preventing energy on the incubation tray 10 from being lost to the area above it via the card dispensing turntable 70. In this way, the incubation tray 10 has a good temperature control effect on the reagent card 60 located above its top surface 11.
[0052] Please see Figure 4 In one embodiment, the reagent card incubation mechanism further includes a drive mechanism 91. The drive mechanism 91 is connected to the card dispensing turntable 70 and is used to drive the card dispensing turntable 70 to rotate.
[0053] Please see Figure 4 In one embodiment, the card-dispensing turntable 70 has a plurality of mating teeth 72 on its circumferential outer edge. The drive mechanism 91 includes a first motor 911 and a gear 912 coaxially connected to the shaft of the first motor 911. The mating teeth 72 mesh with the gear 912. Thus, when the shaft of the first motor 911 rotates, it drives the gear 912 to rotate, and when the gear 912 rotates, it correspondingly drives the mating teeth 72 to move, thereby driving the card-dispensing turntable 70 to rotate on the incubation tray 10. In addition, this design can both amplify the transmission of force and reduce the installation area and related limitations of traditional intermediate drives.
[0054] Please see Figure 4 and Figure 5 Specifically, the first motor 911 is mounted on the insulation cover 80 via a mounting bracket. The insulation cover 80 has a perforated opening, through which the gear 912 extends into the interior of the insulation cover 80 to mesh with the mating teeth 72 of the incubation tray 10.
[0055] Please see Figures 4 to 7 , Figure 6 A cross-sectional view of a reagent card incubation mechanism according to an embodiment of the present invention is shown. Figure 7 It shows Figure 6 An enlarged structural diagram at point A. In one embodiment, the reagent card incubation mechanism further includes an evaporation plate 92. A circumferentially arranged guide groove 12 is formed on the outer periphery of the top surface 11, and a guide hole 13 communicating with the guide groove 12 is also provided on the incubation plate 10. The evaporation plate 92 is located below the incubation plate 10 and is used to receive condensate falling from the guide hole 13. Thus, during operation, the card dispensing turntable 70 drives the reagent card 60 to rotate, and at the same time, the incubation plate 10 reduces the temperature of the reagent card 60 to within a preset range by contacting the reagent card 60 to achieve the incubation operation. Specifically, when the top surface 11 of the incubation plate 10 generates condensate upon contact with heated air, the rotating reagent card 60 throws the condensate generated on the surface of the incubation plate 10 into the guide groove 12 by centrifugal force. The condensate collected in the guide groove 12 falls downward into the evaporation plate 92 through the guide hole 13. By promptly evaporating the condensate inside the evaporator 92, there is no need to worry about the water overflowing from the evaporator 92, nor is there a need for manual emptying of the water. This timely removal of condensate ensures that the product performance is not affected by the condensate.
[0056] In one embodiment, the thermoelectric cooler 20 is also connected to the evaporator 92 via a heat sink 51. Thus, the heat sink 51 can transfer heat to the evaporator 92, which uses this heat to heat and evaporate the condensate inside.
[0057] In another embodiment, the reagent card incubation mechanism further includes a heater (not shown in the figure). The heater is used to heat the evaporation pan 92 so that the condensate inside evaporates. The heater includes, but is not limited to, various heating structures such as heating wires and heating rods.
[0058] In one embodiment, the reagent card incubation mechanism further includes a chassis (not shown in the figure). The incubation tray 10, card dispensing turntable 70, evaporation tray 92, heating mechanism, and heat dissipation assembly 50 are all disposed inside the chassis. The chassis is provided with an air inlet and an air outlet; the evaporation tray 92 and the cooling fan 54 are arranged sequentially on the air duct formed by the air inlet and the air outlet. The air inlet is positioned opposite to the evaporation tray 92, and the air outlet is positioned opposite to the cooling fan 54. Thus, when the cooling fan 54 is working, it generates power, causing air from outside the chassis to enter through the air inlet, flow sequentially through the evaporation tray 92 and the heat dissipation assembly 50, and then be discharged to the outside of the chassis through the air outlet. This allows the hot steam generated by the evaporation tray 92 to be smoothly discharged to the outside of the chassis, thereby preventing the hot steam inside the chassis from adversely affecting the testing instruments inside the chassis.
[0059] Please see Figures 4 to 7 In one embodiment, the reagent card incubation mechanism further includes a flow guide 93. One end of the flow guide 93 is connected to the wall of the flow guide hole 13, and the other end of the flow guide 93 extends into the evaporation plate 92. Thus, under the guiding action of the flow guide 93, the condensate inside the flow guide groove 12 is smoothly discharged into the evaporation plate 92 through the flow guide hole 13.
[0060] Optionally, the flow guide 93 includes, but is not limited to, a flow guide tube, a flow guide rod, etc. In this embodiment, the flow guide 93 is configured as a flow guide tube. Specifically, the cross-section of the flow guide tube decreases from the flow guide hole 13 to the evaporation plate 92, thereby enabling the condensate to be collected inside the evaporation plate 92.
[0061] In one embodiment, the reagent card incubation mechanism further includes a blower (not shown in the figure). The outlet side of the blower faces the evaporation pan 92. Thus, the blower blows air onto the evaporation pan 92, which can accelerate the evaporation of condensate inside the evaporation pan 92.
[0062] Optionally, the blowing device may include, but is not limited to, a fan, or other device capable of delivering gas into the evaporator 92 to accelerate the evaporation of condensate inside the evaporator 92.
[0063] In one embodiment, the insulation plate 40 also has a second window 42 adapted to the flow guide 93. The flow guide 93 passes through the second window 42.
[0064] Please see Figures 4 to 8 , Figure 8A schematic diagram of the card dispensing assembly 94 according to an embodiment of the present invention is shown. In one embodiment, the reagent card incubation mechanism further includes a card dispensing assembly 94 for pushing out the reagent card 60 in the receiving tank 71 along the radial direction of the incubation tray 10. The card dispensing assembly 94 includes a pushing mechanism 941 and a pushing member 942 connected to the pushing mechanism 941. The incubation tray 10 is provided with a radially arranged movable opening 14, and the pushing member 942 is movably disposed in the movable opening 14. Thus, when the pushing mechanism 941 drives the pushing member 942 to move along the movable opening 14, the pushing member 942 can push the reagent card 60 on the incubation tray 10 to the outside of the receiving tank 71 along the radial direction of the incubation tray 10, realizing the card dispensing operation. At the same time as the card dispensing operation, the reagent card 60 acts as a scraper, that is, scraping the condensate on the surface of the incubation tray 10 into the guide groove 12.
[0065] Please see Figure 1 and Figure 8 In addition, in order to avoid the pusher 942, the fitting part 31 is provided with a relief opening 311 to avoid the pusher 942, so that the pusher 942 passes through the relief opening 311 and extends into the movable opening 14.
[0066] Optionally, the driving mechanism 941 may include, but is not limited to, motor screw driving, transmission belt driving, transmission chain driving, gear 912 rack and pinion driving, cylinder driving, hydraulic cylinder driving, etc. The specific mechanism can be flexibly selected and set according to actual needs, and is not limited here.
[0067] Please see Figure 8 In one specific embodiment, the pushing mechanism 941 includes a bracket 9411, a second motor 9412 mounted on the bracket 9411, a driving wheel 9413 and a driven wheel 9414 mounted on the bracket 9411, and a transmission element 9415 connecting the driving wheel 9413 and the driven wheel 9414. The shaft of the second motor 9412 is connected to the driving wheel 9413 and is used to drive the driving wheel 9413 to rotate. The transmission element 9415 is connected to the pushing member 942 and is used to drive the pushing member 942 to move back and forth. Optionally, the pushing member 942 is slidably mounted on the bracket 9411 to ensure operational stability.
[0068] Please see Figure 4 In one embodiment, the incubation tray 10 has a circumferentially arranged baffle 15 on its edge, which protrudes above the top surface 11. In this way, the baffle 15 acts as a liquid barrier, preventing the condensate on the surface of the incubation tray 10 from being thrown out of the incubation tray 10 under the action of centrifugal force, and allowing the condensate to enter the guide groove 12.
[0069] Please see Figure 1 , Figure 4 and Figure 8The baffle 15 is also provided with a discharge port 151 opposite to the movable port 14. When the pushing mechanism 941 drives the pushing member 942 to make the reagent card 60 move radially along the incubation tray 10, the reagent card 60 is discharged out through the discharge port 151.
[0070] Please see Figures 1 to 4 In one embodiment, a medical testing device includes a reagent card incubation mechanism according to any of the above embodiments.
[0071] In the aforementioned medical testing device, during use, the semiconductor cooling element 20 transfers heat / cold energy to the central part of the bottom surface, and the heat / cold energy at the central part of the bottom surface is conducted to its surroundings, thereby ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and detection efficiency of the reagent card 60; or, the semiconductor cooling element 20 transfers heat / cold energy to the circumferential edge of the bottom surface, and the heat / cold energy at the circumferential edge of the bottom surface is conducted to its center, similarly ensuring the uniformity of the incubation area of the incubation tray 10 in the circumferential direction, and thus ensuring the detection accuracy and detection efficiency of the reagent card 60.
[0072] In one embodiment, the calculation scheme of this embodiment is as follows:
[0073] By monitoring the ambient temperature and the temperature of the incubation tray, and by using the control formula t = T_tray - T_ring, and by comparing whether the t value is positive or negative, the MCU controls the direction of the Peltier current, changing the cold and hot ends of the Peltier, thereby achieving temperature control of the incubation tray.
[0074] The dynamically adjusted heating output is denoted as u(k).
[0075] u(k)=Kp*e(k)+Ka*Ki*∑e(j)+Kb*Kd*[e(kn)-e(k0)].
[0076] When |e(j)|≤A, ka=1; when |e(j)|>A, ka=0, and A is the integration threshold.
[0077] When |e(kn)-e(k0)|≤B, kb=1; when |e(kn)-e(k0)|>B, kb=0, where B is the differential action threshold, Kp, Ki, and Kd are the proportional, integral, and differential action coefficients, respectively, e(k) is the input deviation, ∑e(j) is the sum of input deviations, and e(kn) is the measured value.
[0078] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0079] The above embodiments merely illustrate several implementation methods of this application, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the patent application. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of this application, and these all fall within the protection scope of this application. Therefore, the protection scope of this patent application should be determined by the appended claims.
[0080] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.
[0081] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.
[0082] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.
[0083] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.
[0084] It should be noted that when an element is referred to as being "fixed to" or "set on" another element, it can be directly on the other element or there may be an intervening element. When an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intervening element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only possible implementation.
Claims
1. A reagent card incubation mechanism, characterized by, The reagent card incubation mechanism comprises a constant-temperature incubation assembly, and further comprises a card dialing turntable; The constant-temperature incubation assembly comprises: an incubation disc, which is provided with a top surface for supporting a reagent card and a bottom surface opposite to the top surface, and the card dialing turntable is rotationally arranged on the incubation disc, and the card dialing turntable is provided with a plurality of accommodating grooves adapted to the reagent card, and the card dialing turntable is used for driving the reagent card to rotate, and the groove opening of the accommodating grooves faces the top surface, and the top surface is a plane and abuts against the reagent card; and a semiconductor refrigeration device, which is connected with the incubation disc and is used for transferring heat to a middle part of the bottom surface, so that the middle part of the bottom surface is heated earlier than other areas of the bottom surface; or, the semiconductor refrigeration device is used for transferring heat to a circumferential edge part of the bottom surface, so that the circumferential edge part of the bottom surface is heated earlier than other areas of the bottom surface; the constant-temperature incubation assembly further comprises a first heat conduction device arranged between the incubation disc and the semiconductor refrigeration device; the first heat conduction device is connected with the semiconductor refrigeration device; the first heat conduction device is further connected with the middle part of the bottom surface, or the first heat conduction device comprises an annular connecting part arranged in correspondence with the circumferential edge part of the bottom surface, and the annular connecting part is connected with the circumferential edge part of the bottom surface; the first heat conduction device comprises a fitting part connected with the middle part of the bottom surface and a heat conduction part connected with the fitting part, and the heat conduction part is spaced apart from the bottom surface or connected with the bottom surface through a low-heat-conduction material, and the heat conduction part is connected with the semiconductor refrigeration device, and the semiconductor refrigeration device is located at a peripheral part of the bottom surface.
2. The reagent card incubation mechanism of claim 1, wherein, the bottom surface is formed with a recess adapted to the first heat conduction device, and the first heat conduction device is arranged in the recess; a bottom wall of the recess is in a stepped shape and comprises a first wall surface and a second wall surface connected with the first wall surface, the fitting part abuts against the first wall surface, and the heat conduction part is spaced apart from the second wall surface.
3. The reagent card incubation mechanism of claim 1 or 2, wherein, the constant-temperature incubation assembly further comprises an insulation plate; the insulation plate abuts against the bottom surface of the incubation disc.
4. The reagent card incubation mechanism of claim 3, wherein, the constant-temperature incubation assembly further comprises a heat dissipation assembly; the insulation plate is provided with a first window corresponding to the position of the semiconductor refrigeration device, and the heat dissipation assembly is connected with the semiconductor refrigeration device through the first window.
5. The reagent card incubation mechanism of claim 4, wherein, the heat dissipation assembly comprises a heat dissipation plate, a second heat conduction device, a heat dissipation fin and a heat dissipation fan; the heat dissipation plate is connected with the heat dissipation fin through the second heat conduction device, and the heat dissipation fan is connected with the heat dissipation fin.
6. The reagent card incubation mechanism of claim 1, wherein, the reagent card incubation mechanism further comprises an insulation cover, which is connected with the incubation disc and covers the outside of the card dialing turntable.
7. The reagent card incubation mechanism of claim 1, wherein, the reagent card incubation mechanism further comprises a driving mechanism connected with the card dialing turntable and used for driving the card dialing turntable to rotate.
8. The reagent card incubation mechanism of claim 7, wherein, a plurality of matching teeth are arranged on the circumferential edge of the card dialing turntable; the driving mechanism comprises a first motor and a gear coaxially connected with the rotating shaft of the first motor; the matching teeth and the gear are in meshing engagement.
9. The reagent card incubation mechanism of claim 1, wherein, The reagent card incubation mechanism further comprises an evaporation tray; a peripheral portion of the top surface is formed with a circumferentially arranged flow guide groove, and the incubation tray is further provided with a flow guide hole in communication with the flow guide groove; the evaporation tray is located below the incubation tray and is used to receive condensed water falling from the flow guide hole; and / or the reagent card incubation mechanism further comprises a card ejection assembly for ejecting the reagent card in the accommodation groove along a radial direction of the incubation tray; the card ejection assembly comprises a pushing mechanism and a pushing member connected to the pushing mechanism; the incubation tray is provided with a movable opening arranged along the radial direction, and the pushing member is movably arranged in the movable opening.
10. A medical testing device, characterized by The medical detection device comprises the reagent card incubation mechanism according to any one of claims 1 to 9.
Citation Information
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