Thrombectomy device

Abstract

The present invention discloses a thrombus extraction device, comprising: a suction catheter for suctioning thrombus; a filter assembly disposed in the suction catheter and movable along an axial direction parallel to the suction catheter, the distal end of the filter assembly being extendable out of the distal end of the suction catheter during axial movement of the filter assembly; the filter assembly comprising a delivery tube and a filter screen; the delivery tube being housed in the suction catheter and movable along an axial direction parallel to the suction catheter, the distal end of the delivery tube being extendable out of the distal end of the suction catheter; the distal end of the delivery tube having a first state of contraction when located in the suction catheter and a second state of expansion when located outside the suction catheter; the filter screen being connected to the distal end of the delivery tube, such that the filter screen is retracted and expanded with the first and second states of the delivery tube. The present invention aims to at least solve the problem of escaped thrombus shedding.

Description

TECHNICAL FIELD

[0001] The present application belongs to the technical field of medical devices, and particularly relates to a thrombus extraction device. BACKGROUND

[0002] A thrombus is a small mass formed on the surface of a blood vessel in the cardiovascular system at a site of intimal peeling or repair, and is composed of insoluble fibrin, deposited platelets, accumulated white blood cells, and trapped red blood cells. Current methods for treating thrombus include drug anti-thrombus treatment and physical restoration of blood vessel patency by artificial mechanical methods. However, the concentration of thrombolytic anticoagulant drugs that enter the blood vessels cannot be too high, otherwise side effects and toxicity will occur in the human body. At the same time, due to the metabolism and excretion of drugs in the human body, the concentration of antithrombotic drugs present in the blood vessels is relatively low, and the use of antithrombotic drugs has the disadvantage of slow effect, and cannot be used for rescue of acute myocardial infarction, cerebral vascular infarction, acute deep vein thrombosis of the lower extremities, and other acute thrombotic diseases. For such diseases, the only method is to physically extract the thrombus.

[0003] At present, there are thrombus aspiration catheters on the market that can slow down the thrombus to block blood flow and restore blood supply. However, when the existing thrombus aspiration catheters aspirate thrombus, the thrombus will escape after being loosened, escape with the blood flow to the small blood vessels, and cause blockage of the downstream blood vessels, resulting in the occurrence of new thrombus. For large thrombus aspiration, the large thrombus will block the aspiration port, resulting in the need to withdraw the thrombus aspiration catheter for processing and then re-insert it into the human body, prolonging the operation time and increasing the difficulty of the operation. For sub-thrombus or old thrombus, which is tightly adsorbed on the blood vessel wall, ordinary aspiration may not be able to aspirate it, thereby causing the operation to fail. SUMMARY

[0004] The purpose of the present application is to at least solve the problem of thrombus escape. This purpose is achieved in the following way:

[0005] The present application provides a thrombus extraction device, comprising:

[0006] an aspiration catheter for aspirating thrombus;

[0007] a filter assembly arranged in the aspiration catheter and movable in an axial direction parallel to the aspiration catheter, the distal end of the filter assembly being capable of extending out of the distal end of the aspiration catheter during axial movement of the filter assembly;

[0008] The filter assembly comprises a delivery tube and a filter screen; the delivery tube is contained in the suction conduit and is movable along the axial direction parallel to the suction conduit, and the distal end of the delivery tube can extend out of the distal end of the suction conduit; the distal end of the delivery tube has a first state of contraction when located in the suction conduit and a second state of expansion when located outside the suction conduit; the filter screen is connected to the distal end of the delivery tube, so that the filter screen is tightened and unfolded with the first and second states of the delivery tube.

[0009] In some embodiments of the present application, a spray channel is arranged in the delivery tube, and a spray hole is arranged in the distal end of the delivery tube and penetrates the spray channel; in the second state, the spray hole is opposite to the suction port of the suction conduit.

[0010] In some embodiments of the present application, the distal end of the delivery tube is provided with an annular portion, the inside of the annular portion is provided with part of the spray channel, and the annular portion is provided with the spray hole penetrating the spray channel.

[0011] In some embodiments of the present application, the annular portion comprises a ring tube and at least one spray tube, the proximal end of the filter screen is connected to the ring tube, and the distal end of the filter screen is arranged in a spaced manner with the distal end of the delivery tube, the two ends of the spray tube are connected to the ring tube respectively, and the spray tube and / or the ring tube is provided with the spray hole.

[0012] In some embodiments of the present application, the filter assembly further comprises a pull wire, one end of the pull wire is annularly arranged in the inside of the annular portion, and the other end of the pull wire is arranged to extend out of the suction conduit.

[0013] In some embodiments of the present application, the inside of the annular portion is further annularly provided with part of a pull wire channel, the part of the pull wire channel is arranged on the outside of the spray channel along the radial direction or the part of the pull wire channel is arranged on the distal end side of the spray channel along the axial direction, and one end of the pull wire is annularly arranged in the inside of the part of the pull wire channel.

[0014] In some embodiments of the present application, the inside of the suction conduit is provided with a suction cavity along the axial direction, and the pull wire and the delivery tube are arranged in the suction cavity and arranged side by side.

[0015] In some embodiments of the present application, the inside of the suction conduit is provided with a suction cavity and a push cavity along the axial direction, the suction cavity and the push cavity are arranged side by side, and the pull wire and the delivery tube are arranged in the push cavity.

[0016] In some embodiments of the present application, the delivery tube further comprises a tubular body portion, a distal end of the tubular body portion being connected with the annular portion, the tubular body portion comprising an inner tube and an outer tube sleeved outside the inner tube, an inner portion of the inner tube forming another part of the jetting channel, and another part of the wire drawing channel being formed between the inner tube and the outer tube.

[0017] In some embodiments of the present application, the distal end face of the push cavity is flush with the distal end face of the suction cavity, or the distal end face of the push cavity is arranged closer to the proximal end of the suction catheter than the distal end face of the suction cavity, or the distal end face of the push cavity is arranged farther away from the proximal end of the suction catheter than the distal end face of the suction cavity.

[0018] In some embodiments of the present application, the thrombus extraction device further comprises a suction catheter seat, the suction catheter seat being provided with rotatable first and second adjusting knobs, the first adjusting knob being connected with the delivery tube for driving the delivery tube to move in the axial direction of the suction catheter, and the second adjusting knob being connected with the wire for driving the wire to move in the axial direction of the suction catheter.

[0019] In some embodiments of the present application, the distal suction port of the suction catheter is in a wedge-shaped structure inclined to the axis thereof, and the wedge angle of the wedge-shaped structure ranges from 10° to 40°.

[0020] In the thrombus extraction device of the present application, the filter assembly is in a contracted state and is movably arranged at the side portion inside the suction catheter. In use, the filter assembly can be extended parallel to the distal end of the suction catheter and expanded, and the filter screen is unfolded with the expansion to effectively collect the detached thrombus, prevent the thrombus from escaping, and improve the collection effect. Furthermore, since the filter assembly is arranged at the side portion inside the suction catheter, it does not occupy the effective suction cross section of the suction port and does not block the inclined suction port, so as to further ensure the suction effect. In addition, the jetting channel is arranged in the delivery tube, the jetting hole at the distal end of the delivery tube in the expanded filter assembly is opposite to the suction port of the suction catheter, so that the liquid jetted through the delivery tube can jet the suction port of the suction catheter, thereby forcefully breaking the large thrombus blocked at the suction port, preventing the large thrombus from blocking the suction port during the thrombus suction process, and thus realizing continuous suction. In addition, when the jetted liquid is a drug solution, the jetted drug solution can soften the thrombus firmly adsorbed on the blood vessel wall, which helps the thrombus to be detached from the blood vessel wall, and further improves the suction and collection effect. BRIEF DESCRIPTION OF DRAWINGS

[0021] Various other advantages and benefits will become apparent to those skilled in the art upon reading the detailed description of the preferred embodiment below. The accompanying drawings are for illustration purposes only and are not to be considered as limiting the present invention. The same reference numerals are used throughout the accompanying drawings to denote the same components.

[0022] Figure 1 This is a partial structural diagram of the thrombus removal device according to the first embodiment of the present application when the distal end of the delivery tube is in the first state;

[0023] Figure 2 for Figure 1 A schematic diagram of a portion of the structure when the distal end of the middle delivery tube is outside the suction catheter and is not expanded;

[0024] Figure 3 for Figure 2 A schematic diagram of a portion of the structure in which the distal end of the middle delivery tube is located outside the suction catheter and is expanded;

[0025] Figure 4 for Figure 3 Schematic diagram of the cross-sectional structure of section AA in FIG;

[0026] Figure 5 for Figure 3 Schematic diagram of the cross-sectional structure of section BB in FIG;

[0027] Figure 6 for Figure 3 Schematic diagram of the cross-sectional structure of section CC in FIG.

[0028] Figure 7 for Figure 3 The enlarged structural diagram of the middle D part;

[0029] Figure 8 This is a partial structural diagram of the second embodiment of the present application, in which the distal end of the delivery tube is outside the suction catheter and is expanded;

[0030] Figure 9 for Figure 8 Schematic diagram of the cross-sectional structure of section EE in FIG;

[0031] Figure 10 This is a partial structural diagram of the third embodiment of the present application, in which the distal end of the delivery tube is outside the suction catheter and is expanded;

[0032] Figure 11 for Figure 10 Schematic diagram of the cross-sectional structure of section FF in FIG;

[0033] Figure 12 for Figure 10 Schematic diagram of the cross-sectional structure of section GG in FIG.

[0034] The reference numerals in the drawings represent the following:

[0035] 1: Thrombectomy device

[0036] 10: Aspiration catheter, 11: Aspiration lumen, 12: Push lumen, 13: Guide wire lumen

[0037] 20: Filter assembly, 21: Delivery tube, 211: Annular portion, 2111: Ring tube, 21111: Ejection passage, 21112: Wire drawing passage, 2112: Ejection tube, 21121: Ejection hole, 212: Tubular main body portion, 2121: Inner tube, 2122: Outer tube, 22: Filter screen, 23: Wire drawing

[0038] 30: Aspiration catheter hub, 31: Hub body, 32: First adjustment knob, 33: Second adjustment knob, 311: Aspiration fitting, 312: Injection liquid fitting, 313: Guide wire fitting

[0039] 40: Developing member DETAILED DESCRIPTION

[0040] Exemplary embodiments of the present application will be described herein below with reference to the accompanying drawings. While exemplary embodiments of the present application are shown in the drawings, it is understood that the present application can be embodied in various forms and should not be limited by the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the application to those skilled in the art.

[0041] It is to be understood that the terminology used herein is for the purpose of describing particular example embodiments only and is not intended to be limiting. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. The terms "comprises", "comprising", "includes", "including" and "has" are inclusive and therefore specify the presence of stated features, steps, operations, elements, and / or components, but do not preclude the presence or addition of one or more other features, steps, operations, elements, components, and / or groups thereof. The method steps, processes, and operations described herein are not to be construed as necessarily requiring their performance in the particular order in which they are described, unless specifically identified as an order dependent step. It is also to be understood that additional or alternative steps can be employed.

[0042] Although the terms first, second, third, etc. can be used herein to describe various elements, components, regions, layers and / or sections, these elements, components, regions, layers and / or sections should not be limited by these terms. These terms can be only used to distinguish one element, component, region, layer or section from another region, layer or section. Terms such as "first," "second," and other numerical terms when used herein do not imply a sequence or order unless clearly indicated by the context. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the example embodiments.

[0043] Spatially relative terms, such as "inner," "outer," "inward," "outward," "lower," "bottom," "top," "upper," and the like, can be used herein for ease of description to describe one element or feature's relationship to another element(s) or feature(s) as illustrated in the figures. Such spatially relative terms can be intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "below" or "beneath" other elements or features would then be oriented "above" or "over" the other elements or features. Thus, the example term "below" can encompass both an orientation of above and below. The device can be otherwise oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

[0044] In order to more clearly describe the structure of the present application, the terms "proximal end" and "distal end" are defined as terms commonly used in the field of interventional medicine. Specifically, "distal end" means the end far from the operator during the operation, "proximal end" means the end close to the operator during the operation, "axial direction" means the length direction, and "radial direction" means the direction perpendicular to the "axial direction".

[0045] The application provides a thrombus extraction device, which comprises a suction catheter and a filter assembly. The suction catheter is used for sucking thrombus, and the filter assembly is used for capturing the thrombus downstream of the suction port of the suction catheter. Specifically, the filter assembly is arranged in the suction catheter and can move along the axial direction parallel to the suction catheter, and the distal end of the filter assembly can extend out of the distal end of the suction catheter during the axial movement of the filter assembly. The filter assembly comprises a delivery tube and a filter screen. The delivery tube is arranged in the suction catheter and can move along the axial direction parallel to the suction catheter, and the distal end of the delivery tube can extend out of the distal end of the suction catheter. The distal end of the delivery tube has a first state of being contracted when being located in the suction catheter and a second state of being expanded when being located outside the suction catheter. The proximal end of the filter screen is connected to the distal end of the delivery tube, and the distal end of the filter screen is arranged in a spaced manner with the distal end of the delivery tube, so that the filter screen is tightened and unfolded with the first state and the second state of the delivery tube. In the unfolded state of the filter screen, the filter screen captures the thrombus. The filter screen of the application is directly tightened or unfolded with the forward and backward movement of the self-expandable delivery tube, the response speed is fast, and the overall structure is simple and convenient to operate without other additional support structures. In addition, the distal end of the filter screen is spaced from the delivery tube, so that the distal end of the delivery tube does not enter the filter screen, effectively ensuring the collection space inside the filter screen and as far as possible ensuring the flexibility of the distal end of the thrombus extraction device.

[0046] Based on the above-mentioned thrombus extraction device, the embodiment exemplarily provides a specific implementation of the thrombus extraction device. In combination with Figures 1 to 3 The thrombus extraction device 1 of the embodiment comprises a suction catheter 10 and a filter assembly 20. The suction catheter 10 is used for sucking thrombus, and is provided with a suction cavity and a suction port at the distal end. The filter assembly 20 is arranged in the suction catheter 10 and can move along the axial direction parallel to the suction catheter 10, and the distal end of the filter assembly 20 can extend out of the distal end of the suction catheter 10 during the axial movement of the filter assembly 20. In the embodiment, the filter assembly 20 is arranged on the side of the catheter 10 to avoid the suction cavity as far as possible.

[0047] The filter assembly 20 comprises a delivery tube and a filter screen. The delivery tube is arranged in the side of the suction catheter and can move along the axial direction parallel to the suction catheter, and the distal end of the delivery tube can extend out of the distal end of the suction catheter. The distal end of the delivery tube has a first state of being contracted when being located in the suction catheter and a second state of being expanded when being located outside the suction catheter. The filter screen is connected to the distal end of the delivery tube, so that the filter screen is tightened and unfolded with the first state and the second state of the delivery tube. In the thrombus extraction device of the embodiment, the filter assembly is arranged in the side of the suction catheter in a contracted state, and in use, the filter assembly can extend out of the distal end of the suction catheter in parallel and expand, and the filter screen is unfolded with the expansion to effectively collect the detached thrombus, prevent the thrombus from escaping, improve the collection effect, and further ensure the suction effect because the filter assembly is arranged on the side of the suction catheter and does not occupy the effective suction section of the suction port and does not block the obliquely arranged suction port.

[0048] The suction catheter 10 of the present embodiment is a composite tube provided with a multi-layer structure, generally provided with a three-layer structure, from inside to outside, a PTFE (polytetrafluoroethylene) inner liner layer, a S304 steel spring layer or a braided layer, and a Pebax (polyether block polyamide) or nylon layer, or from inside to outside, a PTFE tube, a Pebax tube, a nylon tube or a TUP (thermoplastic polyurethane elastomer rubber) tube, or a tube mixed with multiple materials. The above-mentioned types of composite tubes have good support performance and flexibility, facilitating the delivery and bending of the suction catheter 10 in the blood vessel.

[0049] In combination with Figure 3 , Figure 4 and Figure 5 , the inside of the suction catheter 10 of the present embodiment is provided with a suction lumen 11, a push lumen 12 and a guide wire lumen 13 in the axial direction at the same time, and the suction lumen 11, the push lumen 12 and the guide wire lumen 13 are arranged side by side. The distal end of the suction catheter 10 is provided with a protruding end protruding from the distal end face of the distal end of the suction catheter 10, which can be used to guide the catheter 10 to be delivered in the blood vessel, and the distal ends of the guide wire lumen 13 and the push lumen 12 respectively penetrate the distal end face of the protruding end. The protruding end has a certain taper, is made of TPU or Pebax material, has a hardness of 30D to 55D, has a certain flexibility, and prevents the protruding end from causing damage to the blood vessel wall during movement. The guide wire can be extended to the outside of the suction catheter 10 through the distal end face of the protruding end, so as to guide the suction catheter 10 to move in the blood vessel. In the present embodiment, the distal end face of the push lumen 12 is flush with the distal end face of the protruding end, that is, it is arranged beyond the distal end face of the suction lumen 11. In other embodiments of the present application, the structure of the protruding end can also be cancelled, so that the distal end face of the push lumen 12 is flush with the distal end face of the suction lumen 11.

[0050] In combination with Figure 1 , Figure 3 and Figure 7 , the filter assembly 20 of the present embodiment includes a delivery tube 21 and a filter screen 22, the delivery tube 21 is accommodated in the suction catheter 10 and can move in the axial direction of the suction catheter 10, and the distal end of the delivery tube 21 can protrude out of the end of the suction catheter 10. The distal end of the delivery tube 21 has a first state of contraction when located in the suction catheter 10 and a second state of expansion when located outside the suction catheter 10. The filter screen 22 is connected to the distal end of the delivery tube 21, so that the filter screen 22 is tightened with the first state of the delivery tube 21, and is unfolded with the second state, at the same time, the delivery tube 21 is provided with a jet channel 21111, and the distal end of the delivery tube 21 is provided with a jet hole 21121 which is penetrated by the jet channel 21111.

[0051] Specifically, the filter screen 22 of the present embodiment is in a conical structure in the expanded state, one end of the filter screen 22 is connected to the distal end of the delivery tube 21 and has an opening, the opening is arranged towards the distal end of the aspiration catheter 10, the other end of the filter screen 22 is in a radial dimension gradually decreasing and finally in a closed structure, the thrombus in the blood vessel can enter the conical structure of the filter screen 22 through the opening and be collected. Wherein, the filter screen 22 is located downstream, it expands with the expansion of the filter assembly, the expanded filter screen 22 can effectively collect the detached thrombus, prevent the thrombus from escaping, and improve the collection effect. Specifically, the filter screen 22 of the present embodiment is a soft wire material, such as a braided mesh composed of metal nickel-titanium wire, PTFE wire, nylon or fiber wire, etc. The delivery tube 21 of the present embodiment includes a tubular main body part 212 and a ring-shaped part 211 in a ring structure in the second state, the ring-shaped part 211 is connected to the distal end of the tubular main body part 212. The ring-shaped part 211 includes a ring tube 2111 and a jet tube 2112 connected to the ring tube 2111, the jet tube 2112 is arranged in the ring structure surrounded by the ring tube 2111, and both ends are respectively connected to the jet channel 21111 inside the ring tube 2111. Specifically, the jet tube 2112 is one of PTFE tube, PEbax tube or TUP tube, with a hardness of 30-50D. If the hardness of the jet tube 2112 is too high, it is not easy to shrink, and if the hardness is too low, the jet hole 21121 will not withstand the high pressure and break when the high-pressure liquid is jetted. The ring tube 2111 is one of PTFE tube, PEbax tube or TUP tube, with a hardness of 30-50D. If the hardness of the ring tube 2111 is too high, it is not easy to shrink, and if the hardness is too low, the strength is not enough, and the release retraction process may break. The delivery tube 212 is one or a mixture of more than one of nylon, Pebax, TUP material, with a hardness of 63-80D, the delivery tube 212 needs to be pushed and retracted, the hardness is higher than that of the jet tube 2112, but too high will cause the flexibility of the whole aspiration catheter 10 to be poor, so that the resistance will be too large when pushing through the bend, affecting the use

[0052] Specifically, the proximal end of the filter screen 22 is connected to the ring tube 2111, and the jet tube 2112 is provided with a jet hole 21121 facing the suction conduit 10. When the distal end of the delivery tube 21 is in the expanded second state, the jet tube 2112 is arranged opposite to the distal end of the suction conduit 10, and the liquid is sprayed towards the distal end of the suction conduit 10 through the jet hole 21121. The thrombus between the distal end of the suction conduit 10 and the annular part 211 is broken down and separated from the blood vessel wall under the impact of the sprayed liquid, and finally flows to the inside of the filter screen 22 with the blood flow, and is collected by the filter screen 22 to prevent the thrombus from escaping. At the same time, since the jet direction of the jet hole 21121 in the present embodiment is arranged towards the distal end of the suction conduit 10, rather than towards the blood vessel wall, the damage to the blood vessel wall caused by the liquid during spraying can be effectively reduced, further reducing the damage to the patient. The jet direction of the jet hole 21121 can be at any angle with the distal end face of the suction conduit 10, and preferably, the jet direction of the jet tube 2112 can be perpendicular to the distal end face of the suction conduit 10, thereby minimizing the damage to the patient. In the present embodiment, the liquid sprayed by the jet tube 2112 can be a drug liquid capable of dissolving thrombus. After the drug liquid is sprayed, it can not only directly impact the large thrombus at the suction port of the suction conduit to break the thrombus, but also soften the sub-thrombus or old thrombus adsorbed on the blood vessel wall in the blood vessel, helping the thrombus to fall off from the blood vessel wall, and further improving the suction and collection effect.

[0053] In other embodiments of the present application, the jet hole 21121 can also be provided on the jet tube 2112 and the ring tube 2111, or the jet tube 2112 and the jet hole 21121 thereon can be removed, and only the jet hole 21121 facing the distal end face of the suction conduit 10 is provided on the ring tube 2111.

[0054] Further combined Figure 3 and Figure 7 As shown in the drawings, the filter assembly 20 of the present embodiment further includes a pull wire 23, one end of which is annularly arranged inside the annular part 211, and the other end of which passes out to the outside of the proximal end of the suction conduit 10. By operating the pull wire 23 at the proximal end, the annular part 211 can be driven to shrink and deform by the tightening of the pull wire 23, thereby facilitating the installation of the annular part 211 inside the suction conduit 10 and the delivery. When the annular part 211 extends to the outside of the suction conduit 10, the pull wire 23 is released, and the annular part 211 recovers to the expanded state under the action of its own elastic deformation, and drives the filter screen 22 to expand, thereby collecting the falling thrombus through the filter screen 22. Specifically, the pull wire 23 of the present embodiment is made of a memory alloy (titanium nickel, titanium nickel iron, titanium nickel chromium, copper nickel), and the distal end of the pull wire 23 is welded or bonded to the connection between the annular part 211 and the tubular main part 212.

[0055] Specifically, asFigure 7 As shown, the inner part of the ring tube 2111 is simultaneously provided with the partial liquid injection channel 21111 and the partial wire drawing channel 21112, the partial wire drawing channel 21112 is provided at the outer side of the partial liquid injection channel 21111 along the radial direction, the distal end of the wire 23 is provided in the wire drawing channel 21112, and the proximal end of the wire 23 is drawn out to the outside of the proximal end of the suction catheter 10, thereby facilitating the operation. In the present embodiment, in order to prevent the existence of the wire 23 from causing obstruction to the flow of liquid in the injection channel 21111, the partial liquid injection channel 21111 and the partial wire drawing channel 21112 are simultaneously provided in the ring tube 2111. In other embodiments of the present application, the wire drawing channel 21112 can also be provided at the distal end side of the liquid injection channel 21111 along the axial direction, which can also prevent the wire 23 from causing obstruction to the flow of liquid and effectively prevent the wire drawing channel 21112 from causing obstruction in the liquid injection path. In other embodiments of the present application, the wire 23 can also be provided in the liquid injection channel 21111, that is, only the liquid injection channel 21111 is provided in the ring tube, and the distal end of the wire 23 is provided in the liquid injection channel 21111.

[0056] Further, in combination with Figure 4 and Figure 5 As shown, in order to ensure the smooth delivery of the wire 23 during delivery, especially to prevent the wire 23 from being twisted and deformed when it is drawn out to the outside of the suction catheter 10, the delivery tube 21 of the present embodiment is further provided with another partial wire drawing channel 21112. Specifically, the tubular main body part 212 of the present embodiment includes an inner tube 2121 and an outer tube 2122 sleeved on the outside of the inner tube 2121, the inner part of the inner tube 2121 forms another partial liquid injection channel 21111, and the inner tube 2121 and the outer tube 2122 form another partial wire drawing channel 21112. When the distal end of the delivery tube 21 is drawn out to the outside of the suction catheter 10, the wire 23 is always in the wire drawing channel 21112 of the delivery tube 21 and will not be twisted and deformed in the blood vessel, thereby ensuring the normal flow of blood and effective collection of thrombus.

[0057] In the present embodiment, only the part close to the distal end of the inner tube 2121 is sleeved with the outer tube 2122, thereby preventing the wire 23 from being twisted and deformed after being drawn out of the suction catheter 10. In other embodiments of the present application, the entire proximal end to distal end of the delivery tube 21 can also be provided in the form of combination of the inner tube 2121 and the outer tube 2122, thereby further effectively ensuring the running track of the wire 23.

[0058] Further, in combination with Figure 1 and Figure 6As shown, the thrombus extraction device 1 of the embodiment further comprises a suction catheter seat 30, which comprises a seat body 31, and a first adjusting knob 32 and a second adjusting knob 33 rotatably arranged on the seat body 31. The first adjusting knob 32 is connected with the delivery tube 21, and the delivery tube 21 is driven to move along the axial direction of the suction catheter 10 by rotating the first adjusting knob 32, so that the distal end of the delivery tube 21 is extended or retracted into the suction catheter 10. The second adjusting knob 33 is connected with the pull wire 23, and is used to drive the pull wire 23 to move along the axial direction of the suction catheter 10 by rotating the second adjusting knob 33, so as to tighten or expand the ring tube 2111, and further contract and expand the filter screen 22. The seat body 31 is further provided with a suction connector 311, an injection connector 312 and a guide wire connector 313. One end of the suction connector 311 is connected with the suction cavity 11, and the other end of the suction connector 311 can be connected with a negative pressure generator, so that the suction cavity 11 is kept in a negative pressure state by the negative pressure generator, and the thrombus in the blood vessel is extracted. One end of the injection connector 312 is connected with the injection channel 21111 of the delivery tube 21, and the other end of the injection connector 312 can be connected with a liquid injection pump, so as to provide high-pressure or low-pressure liquid into the injection channel 21111 by the liquid injection pump.

[0059] Further, the distal end of the suction catheter 10 of the embodiment is further provided with a developing member 40, specifically a developing ring, which is made of platinum or tantalum and has a developing effect. Specifically, the developing ring is arranged close to the opening at the distal end of the suction catheter 10, so as to facilitate the confirmation of the position of the distal end of the suction catheter 10.

[0060] Further, the distal end of the suction catheter 10 of the embodiment is in a wedge-shaped structure, and the wedge angle of the wedge-shaped structure ranges from 10° to 40°. The suction force is equal to the product of the pressure and the suction port area. Compared with a circular port, the wedge-shaped port can provide greater suction force. When the wedge angle is not more than 40°, the thrombus extraction device 1 has better suction force. When the wedge angle is greater than 10°, the preparation of the wedge-shaped structure at the distal end of the suction catheter 10 is facilitated.

[0061] When the thrombus extraction device 1 of the embodiment is used for intravascular thrombectomy, first, a guide wire is used to establish a path in the blood vessel, and then the guide wire is connected with the guide wire connector 313 of the thrombus extraction device 1, and the guide wire is guided into the suction catheter 10 through the guide wire connector 313. Figure 1The shown state will move the distal end opening of the suction catheter 10 of the thrombus taking device 1 along the guide wire to the upstream of the thrombus lesion position; then rotate the first adjusting knob 32 to make the distal end of the delivery tube 21 extend to the outside of the suction catheter 10 and be at a certain distance from the distal end of the suction catheter 10, so that the filter screen 22 is placed downstream of the thrombus; then rotate the second adjusting knob 33 to make the pull wire 23 in a relaxed state and make the ring tube 2111 automatically expand, and the filter screen 22 is unfolded with the expansion of the ring tube 2111, and the opening of the filter screen 22 is arranged relative to the distal end of the suction catheter 10. Then open the negative pressure generator to suction the thrombus in the blood vessel, and at the same time open the liquid injection pump to make the jet tube 2112 spray low-pressure liquid to soften the thrombus (usually used for old or more solid thrombus), so that the thrombus is separated from the blood vessel wall and facilitates suction. When a large thrombus blocks the suction cavity 11, rotate the first adjusting knob 32 to move the annular part 211 towards the direction of the suction catheter 10, so that the jet tube 2112 reaches near the distal suction port of the suction catheter 10, and then high-pressure liquid is sprayed through the jet tube 2112 to impact the large thrombus and make the large thrombus break, and then the broken thrombus is sucked into the suction cavity 11 inside the suction catheter 10, and finally the suction catheter 10 is withdrawn out of the body after the suction is completed. During the withdrawal out of the body, the second adjusting knob 33 can be rotated first to tighten the pull wire 23 and drive the annular part 211 to shrink and deform, and then the first adjusting knob 32 is rotated to make the annular part 211 of the shrinkage deformation port and the filter screen 22 together with the delivery tube 21 retract into the push cavity 12, and finally the filter assembly 20 and the suction catheter 10 are withdrawn out of the body together, preventing the filter assembly 20 outside the suction catheter 10 from scratching the blood vessel wall during the withdrawal out of the body.

[0062] Embodiment two

[0063] Based on the above-mentioned thrombus taking device, the embodiment exemplarily provides another specific embodiment of a thrombus taking device. In combination with Figure 8 and Figure 9As shown, the thrombus removal device 1 in this embodiment is generally identical to that in the first embodiment, comprising a suction catheter 10, a filter assembly 20, a support base 30, and a developing element 40. The distal end structure of the filter assembly 20 is identical to that in the first embodiment. Unlike the suction catheter 10 in the first embodiment, which has a three-lumen structure comprising a suction lumen 11, a delivery lumen 12, and a guidewire lumen 13, the suction catheter 10 in this embodiment has a dual-lumen structure comprising a suction lumen 11 and a guidewire lumen 13. Among them, the delivery tube 21 and the drawing wire 23 are both arranged in the suction chamber 11 and can move along the axial direction of the suction chamber 11. Therefore, during the suction process of the thrombus, the filter 22 at the distal end of the delivery tube 21 can be withdrawn into the suction chamber 11 of the suction catheter 10 in an expanded state, and liquid is sprayed on the large thrombus in the suction chamber 11 through the injection tube 2112 to increase the impact force on the thrombus, thereby effectively breaking up and dissolving the thrombus in the suction chamber 11, thereby further ensuring the suction process of the thrombus and further preventing the thrombus from escaping.

[0064] Implementation Method 3

[0065] Based on the above-mentioned thrombus removal device, this embodiment provides another specific implementation of the thrombus removal device. Figure 10 、 Figure 11 and Figure 12 As shown, the thrombus removal device 1 in this embodiment is generally identical to that in the first embodiment, comprising a suction catheter 10, a filter assembly 20, a support base 30, and a developing element 40. The distal end structure of the filter assembly 20 is identical to that in the first embodiment. Unlike the three-lumen structure of the suction catheter 10 in the first embodiment, which comprises a suction lumen 11, a delivery lumen 12, and a guidewire lumen 13, the proximal portion of the suction catheter 10 in this embodiment has a three-lumen structure comprising the suction lumen 11, the delivery lumen 12, and the guidewire lumen 13, while the distal portion has a dual-lumen structure comprising the suction lumen 11 and the guidewire lumen 13. Specifically, the distal end of the delivery lumen 12 is positioned closer to the proximal end of the suction catheter 10 than the distal end of the suction lumen 11. The proximal ends of the delivery tube 21 and the wire drawing 23 are both located within the delivery lumen 12 and arranged side by side, ensuring smooth delivery of the delivery tube 21 and the wire drawing 23 within the suction catheter 10. The distal ends of the delivery tube 21 and the drawing wire 23 are both arranged in the suction cavity 11 and arranged side by side, so that during the suction process of the thrombus, the filter 22 at the distal end of the delivery tube 21 can be withdrawn into the suction cavity 11 of the suction catheter 10 in an expanded state, and liquid is sprayed on the large thrombus in the suction cavity 11 through the injection tube 2112 to increase the impact force on the thrombus, effectively crushing and dissolving the thrombus in the suction cavity 11, thereby further ensuring the suction process of the thrombus and further preventing the thrombus from escaping.

[0066] The above merely describes preferred specific embodiments of the present application, but the protection scope of the present application is not limited thereto, any changes or replacements within the technical scope disclosed by the present application, which can be easily thought by those skilled in the art, should be covered within the protection scope of the present application. Therefore, the protection scope of the present application should be subject to the protection scope of the claims.

Claims

1. A thrombectomy device, comprising: The device comprises: a suction catheter for sucking thrombus; a filter assembly arranged in the suction catheter and movable along an axial direction parallel to the suction catheter, the distal end of the filter assembly being capable of extending out of the distal end of the suction catheter during axial movement of the filter assembly; the filter assembly comprises a delivery tube and a filter screen; the delivery tube is arranged in the suction catheter and movable along an axial direction parallel to the suction catheter, and the distal end of the delivery tube is capable of extending out of the distal end of the suction catheter; the distal end of the delivery tube has a first state of contraction when located in the suction catheter and a second state of expansion when located outside the suction catheter; the filter screen is connected to the distal end of the delivery tube, so that the filter screen is tightened and unfolded with the first and second states of the delivery tube; wherein the delivery tube is provided with a jet channel, the distal end of the delivery tube is provided with an annular part, the annular part comprises a ring tube and at least one jet tube, the jet tube is arranged in the annular structure surrounded by the ring tube, the proximal end of the filter screen is connected to the ring tube, and the distal end of the filter screen is spaced apart from the distal end of the delivery tube, the two ends of the jet tube are connected to the ring tube respectively, the jet tube is provided with a jet hole penetrating the jet channel, and the jet direction of the jet hole is arranged towards the distal end of the suction catheter.

2. The thrombectomy device of claim 1, wherein, The filter assembly further comprises a pull wire, one end of the pull wire is annularly arranged in the inner part of the annular part, and the other end of the pull wire is arranged outside the suction catheter.

3. The thrombectomy device of claim 2, wherein, The inner part of the annular part is further annularly provided with a partial pull wire channel, the partial pull wire channel is arranged on the outer side of the jet channel in the radial direction, or the partial pull wire channel is arranged on the distal side of the jet channel in the axial direction, and one end of the pull wire is annularly arranged in the inner part of the partial pull wire channel.

4. The thrombectomy device of claim 3, wherein, The inner part of the suction catheter is provided with a suction cavity in the axial direction, and the pull wire and the delivery tube are jointly arranged in the suction cavity and arranged side by side.

5. The thrombectomy device of claim 3, wherein, The inner part of the suction catheter is provided with a suction cavity and a push cavity in the axial direction, the suction cavity and the push cavity are arranged side by side, the pull wire and the delivery tube are jointly arranged in the push cavity.

6. The thrombectomy device of claim 5, wherein, The delivery tube further comprises a tubular main body part, the distal end of the tubular main body part is connected to the annular part, the tubular main body part comprises an inner tube and an outer tube sleeved outside the inner tube, the inner part of the inner tube forms another part of the jet channel, and another part of the pull wire channel is formed between the inner tube and the outer tube.

7. The thrombectomy device of claim 5, wherein, The distal end face of the push cavity is flush with the distal end face of the suction cavity, or the distal end face of the push cavity is arranged closer to the proximal end of the suction catheter than the distal end face of the suction cavity, or the distal end face of the push cavity is arranged away from the proximal end of the suction catheter than the distal end face of the suction cavity.

8. The thrombectomy device of claim 2, wherein, The thrombus extraction device further comprises a suction catheter seat, the suction catheter seat is provided with a rotatable first adjusting knob and a second adjusting knob, the first adjusting knob is connected to the delivery tube for driving the delivery tube to move along the axial direction of the suction catheter, and the second adjusting knob is connected to the pull wire for driving the pull wire to move along the axial direction of the suction catheter.

9. The thrombectomy device of any of claims 1-8, wherein, The distal suction port of the suction catheter is wedge-shaped with respect to its axis, the wedge angle of the wedge-shaped structure ranging from 10° to 40°.

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