Efficacy composition, application and cosmetics for essence oil or body care oil

Abstract

The present application provides an efficacy composition for essence oil or body care oil, comprising ceramide or its analog, cholesterol or its analog, fatty acid, an antagonist of TRPV1 receptor, triglyceride substances, a sebum wax ester structure analog, and squalene. It aims to prepare an essence oil product with a light texture, weak greasiness, and a comprehensive and effective soothing and repairing effect on sensitive skin problems.

Description

Technical Field

[0001] This application belongs to the field of cosmetics, and particularly relates to an efficacy composition, application and cosmetics for essence oil or body care oil. Background Art

[0002] As a common skin disease in clinics, the incidence of sensitive skin shows an increasing trend year by year. In recent years, the continuous expansion of the scale of China's beauty and skincare market has gradually driven the progress of the industry, the popularization of professionalism and the awakening of awareness. Sensitive skin specifically refers to a highly reactive state that occurs under physiological or pathological conditions. Although most cases only show some allergic symptoms, the various skin discomforts that are prone to recurrence, such as skin sensitivity, flushing, itching, stinging, etc., undoubtedly seriously affect the quality of life of people with such skin problems.

[0003] As an important category in the skin care field at all times and in all over the world, the essence oil dosage form has three characteristics: "essence ingredients", "outstanding efficacy" and "oil carrier". Essence oil has "innate" advantages both in solving the fundamental needs of the skin and meeting the demands of consumers for efficacy. However, factors such as the thick, greasy texture and poor skin feel experience of essence oil products affect the user experience. In addition, due to the complexity of the causes of sensitive skin, researchers often cannot accurately grasp the concept of sensitive skin, and thus provide precise solutions, which brings inconvenience to product development.

[0004] Patent document CN107281040A discloses a repair essence oil for sensitive skin and its preparation method. The composition of the invention is made of the following components in mass percentage: macadamia nut oil 50 - 65%, squalane 15 - 20%, phytosterol 2 - 5%, wheat germ oil 2 - 6%, chamomile essential oil 5 - 10%, everlasting essential oil 2 - 5%, rosemary leaf oil 1 - 2%, myrrh oil 0.2 - 0.5%, vitamin E 1 - 2%, blue chamomile 0.2 - 0.5%. Although this composition can relieve various discomfort symptoms brought by sensitive skin to a certain extent, its skin feel is thick and greasy, and the added essential oils also have a potential high probability of causing allergies. Summary of the Invention

[0005] The technical problem to be solved by this application is to solve the deficiencies in the background art, and provide an efficacy composition with a relatively light texture, weak greasiness, and capable of comprehensively and effectively targeting sensitive skin problems, its application, and a soothing and repairing cosmetic.

[0006] The technical solution of this application is as follows:

[0007] 1. An efficacy composition for essence oil or body care oil, which includes:

[0008] Ceramide or its analog, cholesterol or its analog, fatty acid, antagonist of TRPV1 receptor, triglyceride, sebum wax ester structure analog, squalene.

[0009] 2. The efficacy composition according to item 1, wherein

[0010] The ceramide or its analog is selected from one or two of N-palmitoyl hydroxyproline cetyl ester and ceramide NP;

[0011] The cholesterol or its analog is selected from one or more than two of cholesterol, plant sterol macadamiate, phytosterols, plant sterol rapeseed oleate, and phytosterol / octyldodecyl lauroyl glutamate;

[0012] The fatty acid is selected from one or more than two of stearic acid, oleic acid, linoleic acid, and linolenic acid;

[0013] The antagonist of TRPV1 receptor is 4-tert-butylcyclohexanol;

[0014] The triglyceride is selected from one or more than two of triglyceride C18-36 acid, triglyceride C12-18 acid, triglyceride C8-12 acid, and triglyceride oleic acid / linoleic acid;

[0015] The sebum wax ester structure analog is selected from one or two of jojoba esters and jojoba oil.

[0016] 3. The efficacy composition according to item 1, wherein it includes:

[0017] 1609, 100 and

[0018] Preferably,

[0019] Relative to 1 part by weight of the 1609, the 100 is 0.25 to 4 parts by weight, and the is 0.5 to 3 parts by weight.

[0020] 4. An efficacy composition for essence oil or body care oil, wherein it includes:

[0021] 1609, 100 and

[0022] Preferably,

[0023] Relative to 1 part by weight of the 1609, the 100 is 0.25 to 4 parts by weight, and the is 0.5 to 3 parts by weight.

[0024] 5. The efficacy composition according to item 3 or 4, wherein

[0025] the efficacy composition further comprises an auxiliary efficacy agent, and the auxiliary efficacy agent is selected from one or two of sea fennel extract and wakame extract;

[0026] Preferably,

[0027] relative to 1 part by weight of the 1609, the auxiliary efficacy agent is 0.2 to 2 parts by weight.

[0028] 6. Use of the efficacy composition according to any one of items 1 to 5 in the preparation of essence oil and body care oil.

[0029] 7. A cosmetic, wherein

[0030] it comprises the efficacy composition according to any one of items 1 to 5;

[0031] Preferably, based on the total weight of the cosmetic, the mass percentage of the efficacy composition is 0.5 to 10 wt%;

[0032] More preferably,

[0033] based on the total weight of the cosmetic, the mass percentage of 1609 is 0.01 to 3 wt%, the mass percentage of 100 is 0.01 to 3 wt%, the mass percentage of is 0.1 to 3 wt%, and the mass percentage of the auxiliary efficacy agent is 0.01 to 1 wt%.

[0034] 8. The cosmetic according to item 7, wherein

[0035] the cosmetic further comprises one or more of vegetable oil, silicone oil alternative grease, synthetic grease, antioxidant and anti-inflammatory agent.

[0036] 9. The cosmetic according to item 8, wherein

[0037] based on the total weight of the cosmetic, the vegetable oil is 0.01 to 10 wt%, the silicone oil alternative grease is 1 to 40 wt%, the synthetic grease is 38 to 98.5 wt%, the antioxidant is 0.05 to 1.5 wt%, and the anti-inflammatory agent is 0.01 to 0.26 wt%.

[0038] 10. The cosmetic according to item 8 or 9, wherein,

[0039] the vegetable oil includes Prinsepia utilis Royle oil;

[0040] Preferably,

[0041] the vegetable oil further includes one or more of grape seed oil, jojoba seed oil, Limnanthes alba seed oil, sweet almond oil, and almond oil.

[0042] 11. The cosmetic according to item 10, wherein,

[0043] Based on the total weight of the cosmetic, the mass percentage of the Prinsepia utilis Royle oil is 0.01 wt% to 2 wt%.

[0044] 12. The cosmetic according to item 8 or 9, wherein,

[0045] the silicone oil substitute for grease is selected from one or more of C9-12 alkanes, C13-14 alkanes, C13-15 alkanes, C15-19 alkanes, C15-23 alkanes, C18-21 alkanes, undecane, tridecane, and octadecane.

[0046] 13. The cosmetic according to item 8 or 9, wherein,

[0047] the synthetic grease is selected from one or more of diethylhexyl carbonate, dicaprylyl carbonate, coco-caprylate / caprate, butanediol dicaprylate / dicaprate, dicaprylyl ether, neopentyl glycol diheptanoate, and heptyl undecylenate.

[0048] 14. The cosmetic according to item 8 or 9, wherein,

[0049] the antioxidant is tocopherol and / or tocopheryl acetate.

[0050] 15. The cosmetic according to item 8 or 9, wherein,

[0051] the anti-inflammatory agent is stearyl glycyrrhetinate and / or bisabolol.

[0052] 16. The cosmetic according to item 7, wherein,

[0053] the cosmetic is selected from one of essence oil and body care oil.

[0054] Compared with the prior art, the beneficial effects of the present application are:

[0055] This application aims to develop an essential oil or body care oil product that is lightweight, lacks greasiness, and offers comprehensive, soothing, repairing, and effective treatments for sensitive skin. By selecting lightweight oils whenever possible, the goal of achieving a refreshing, non-greasy feel is achieved. By combining different active ingredients, the essential oil product is designed to comprehensively and effectively address sensitive skin issues by repairing the skin's barrier function and inhibiting neurovascular hyperreactivity, immune responses, and inflammatory responses. This overcomes the shortcomings of existing oil-based essences, which suffer from poor feel and a single or unclear mechanism of action.

[0056] This application is a full oil system, and the material selection also selects a system suitable for this application. As the main component of the skin, oil is of great significance to maintaining the structure and function of the skin. As a pure oil formulation, essence oil can not only seal the sebum membrane, reduce the loss of skin moisture, and play a moisturizing role; it can also repair the skin barrier and strengthen the skin's resistance. The oil formulation itself is easier to penetrate, which can promote the absorption of active ingredients. Combined with biologically active ingredients, it can play an antioxidant, repair, anti-inflammatory, whitening, and anti-aging role. Essential oils or body care oils generally use glass containers, mainly because the properties of glass are relatively stable and not easy to react with other chemical components, which will not affect the efficacy of the essential oil or body care oil. Essential oils or body care oils are refreshing and non-greasy. This is also based on experiments. By replacing different oils, light and non-greasy oils are selected as the final choice. DETAILED DESCRIPTION

[0057] The present application is further described below with reference to examples. It should be understood that the examples are only used to further illustrate and explain the present application and are not intended to limit the present application.

[0058] Unless otherwise defined, technical and scientific terms used in this specification have the same meaning as those commonly understood by those skilled in the art. Although methods and materials similar or identical to those described herein may be used in experiments or practical applications, the materials and methods are described herein below. In the event of a conflict, the present specification, including definitions, will prevail. In addition, the materials, methods, and examples are provided for illustrative purposes only and are not intended to be limiting. The present application is further described below with reference to specific examples, which are not intended to limit the scope of this application.

[0059] A functional composition for essence oil or body care oil, comprising: ceramide or its analogues, cholesterol or its analogues, fatty acids, TRPV1 receptor antagonists, triglycerides, sebum wax ester structural analogues, and squalene.

[0060] In some embodiments of the present application, the ceramide or its analogue is selected from one or both of N-palmitoylhydroxyproline cetyl ester and ceramide NP.

[0061] In some embodiments of the present application, the cholesterol or its analogs are selected from one or more of cholesterol, phytosterol macadamiate, phytosterols, phytosterol rapeseed oleate, and phytosterol / octyldodecyl lauroyl glutamate.

[0062] In some embodiments of the present application, the fatty acid is selected from one or more of stearic acid, oleic acid, linoleic acid, and linolenic acid.

[0063] In some embodiments of the present application, the antagonist of the TRPV1 receptor is 4-tert-butylcyclohexanol.

[0064] In some embodiments of the present application, the triglyceride substances are selected from one or more of triglyceride C18-36 acid, triglyceride C12-18 acid, triglyceride C8-12 acid, and triglyceride oleic acid / linoleic acid.

[0065] In some embodiments of the present application, the sebum wax ester structure analog substances are selected from one or two of jojoba esters and jojoba oil.

[0066] For the efficacy composition of the present application, each component can be combined together according to actual needs, or a composition of certain components existing in the market can be purchased to achieve the function of the efficacy composition and reach the corresponding effect.

[0067] In the present application, for the efficacy composition used in essence oil or body care oil, the single components can be mixed by oneself according to needs to obtain the efficacy composition; or any composition A containing several of the above components can be selected, any composition B containing several of the above components can be selected, and then any composition C containing the remaining components can be selected, and the composition A, composition B, and composition C are compounded to obtain the efficacy composition, as long as it is ensured that the efficacy composition contains the above components. The specific components contained in the composition A, composition B, and composition C can be the same or different.

[0068] In the present application, the content of the above-mentioned efficacy composition can be configured according to needs.

[0069] In some embodiments of the present application, the efficacy composition includes 1609, 100, and

[0070] The present application provides an efficacy composition for essence oil or body care oil, which includes: 1609, 100, and

[0071] The mechanisms of sensitive skin include: damage to the skin barrier function, dysfunction of the skin's sensory nerves, increased vascular reactivity, and immune and inflammatory responses. The TRPV1 receptor (also known as the capsaicin receptor) is closely related to the dysfunction of the skin's sensory nerves and increased vascular reactivity. The main active ingredient in Symsitive 1609, 4-tert-butylcyclohexanol, is an oil-soluble raw material with TRPV1 as a biological target. It is an antagonist of the TRPV1 receptor, which can reduce the skin's reactivity to capsaicin. It is used to control the symptoms of sensitive skin and can quickly relieve the stinging sensation in patients with sensitive skin. In terms of skin barrier function, lipids and sebum membranes play a vital role. SymRepair 100 is a composition designed based on the three key components of human skin lipids: ceramides, cholesterol, and fatty acids. It can replenish skin lipids, thereby helping the skin quickly rebuild a thin bilayer similar to the skin structure, thereby protecting and repairing the skin barrier.

[0072] In this application, The main active ingredient of 1609 is 4-tert-butyl cyclohexanol, an oil-soluble raw material with TRPV1 as its biological target. It is an antagonist of the TRPV1 receptor, which can reduce the skin's reactivity to capsaicin. It is used to control related symptoms of sensitive skin and can quickly relieve the tingling sensation in patients with sensitive skin.

[0073] In this application, Its ingredients are C18-36 acid triglycerides, jojoba esters, C12-18 acid triglycerides, squalene, phytosteryl macadamia oleate, phytosterols and tocopherol (vitamin E). It is designed by simulating the epidermal lipid composition of a 22-year-old healthy human body and can also improve the skin barrier function.

[0074] In this application, the applicant selects 1609, 100 and The three compositions satisfy the requirements of the efficacy composition as long as they simultaneously contain the ingredients "ceramide or its analogues, cholesterol or its analogues, fatty acids, TRPV1 receptor antagonists, triglycerides, sebum wax ester structural analogues, and squalene".

[0075] In this application, the combination of these three can effectively enhance the repair effect of the product.

[0076] In some embodiments of the present application, 1609, 100 and It can come from any company on the market as long as it meets the requirements.

[0077] In some embodiments of the present application, 1609, 100 is from Symrise Aromatics (Nantong) Co., Ltd., is from International Flora Technologies Ltd.

[0078] In some embodiments of the present application, relative to 1 part by weight of 1609, 100 is 0.25 to 4 parts by weight, is 0.5 to 3 parts by weight; for example, relative to 1 part by weight of 1609, 100 can be 0.25 part by weight, 0.5 part by weight, 0.75 part by weight, 1 part by weight, 1.25 part by weight, 1.5 part by weight, 1.75 part by weight, 2 parts by weight, 2.25 part by weight, 2.5 part by weight, 2.75 part by weight, 3 parts by weight, 3.25 part by weight, 3.5 part by weight, 3.75 part by weight, 4 parts by weight or any range therebetween; can be 0.5 part by weight, 0.75 part by weight, 1 part by weight, 1.25 part by weight, 1.5 part by weight, 1.75 part by weight, 2 parts by weight, 2.25 part by weight, 2.5 part by weight, 2.75 part by weight, 3 parts by weight or any range therebetween.

[0079] In some embodiments of the present application, the efficacy composition further includes an auxiliary efficacy agent, wherein the auxiliary efficacy agent is selected from one or more of an oil-soluble extract of Crithmum maritimum and an extract of Undaria pinnatifida.

[0080] In the present application, the extract of Crithmum maritimum is an oil-soluble extract of Crithmum maritimum.

[0081] In some embodiments of the present application, relative to 1 part by weight of 1609, the auxiliary efficacy agent is 0.2 to 2 parts by weight. For example, relative to 1 part by weight of 1609, the auxiliary efficacy agent can be 0.2 part by weight, 0.3 part by weight, 0.4 part by weight, 0.5 part by weight, 0.6 part by weight, 0.7 part by weight, 0.8 part by weight, 0.9 part by weight, 1.0 part by weight, 1.1 part by weight, 1.2 part by weight, 1.3 part by weight, 1.4 part by weight, 1.5 part by weight, 1.6 part by weight, 1.7 part by weight, 1.8 part by weight, 1.9 part by weight, 2.0 part by weight or any range therebetween.

[0082] The present application provides the use of the above-mentioned efficacy composition in the preparation of essence oil and body care oil.

[0083] This application provides a cosmetic, which includes the above-mentioned efficacy composition.

[0084] In some embodiments of this application, based on the total weight of the cosmetic, the mass percentage of the efficacy composition is 0.5 to 10 wt%; for example, based on the total weight of the cosmetic, the mass percentage of the efficacy composition can be 0.5 wt%, 1 wt%, 1.5 wt%, 2 wt%, 2.5 wt%, 3 wt%, 3.5 wt%, 4 wt%, 4.5 wt%, 5 wt%, 5.5 wt%, 6 wt%, 6.5 wt%, 7 wt%, 7.5 wt%, 8 wt%, 8.5 wt%, 9 wt%, 9.5 wt%, 10 wt% or any range therebetween.

[0085] In some embodiments of this application, based on the total weight of the cosmetic, the mass percentage of 1609 is 0.01 to 3 wt%; for example, based on the total weight of the cosmetic, the mass percentage of 1609 can be 0.01 wt%, 0.05 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.0 wt%, 1.1 wt%, 1.2 wt%, 1.3 wt%, 1.4 wt%, 1.5 wt%, 1.6 wt%, 1.7 wt%, 1.8 wt%, 1.9 wt%, 2.0 wt%, 2.1 wt%, 2.2 wt%, 2.3 wt%, 2.4 wt%, 2.5 wt%, 2.6 wt%, 2.7 wt%, 2.8 wt%, 2.9 wt%, 3.0 wt% or any range therebetween.

[0086] In some embodiments of this application, based on the total weight of the cosmetic, the mass percentage of 100 is 0.01 to 3 wt%; for example, based on the total weight of the cosmetic, the The mass percentage of 100 can be 0.01wt%, 0.05wt%, 0.1wt%, 0.2wt%, 0.3wt%, 0.4wt%, 0.5wt%, 0.6wt%, 0.7wt%, 0.8wt%, 0.9wt%, 1.0wt%, 1.1wt%, 1.2wt%, 1.3wt%, 1.4wt%, 1.5wt%, 1.6wt%, 1.7wt%, 1.8wt%, 1.9wt%, 2.0wt%, 2.1wt%, 2.2wt%, 2.3wt%, 2.4wt%, 2.5wt%, 2.6wt%, 2.7wt%, 2.8wt%, 2.9wt%, 3.0wt% or any range therebetween.

[0087] In some embodiments of the present application, based on the total weight of the cosmetic, the has a mass percentage of 0.1 - 3wt%. For example, based on the total weight of the cosmetic, the has a mass percentage that can be 0.01wt%, 0.05wt%, 0.1wt%, 0.2wt%, 0.3wt%, 0.4wt%, 0.5wt%, 0.6wt%, 0.7wt%, 0.8wt%, 0.9wt%, 1.0wt%, 1.1wt%, 1.2wt%, 1.3wt%, 1.4wt%, 1.5wt%, 1.6wt%, 1.7wt%, 1.8wt%, 1.9wt%, 2.0wt%, 2.1wt%, 2.2wt%, 2.3wt%, 2.4wt%, 2.5wt%, 2.6wt%, 2.7wt%, 2.8wt%, 2.9wt%, 3.0wt% or any range therebetween.

[0088] In some embodiments of the present application, based on the total weight of the cosmetic, the mass percentage of the auxiliary efficacy agent is 0.01 - 1wt%; for example, based on the total weight of the cosmetic, the mass percentage of the auxiliary efficacy agent can be 0.01wt%, 0.05wt%, 0.1wt%, 0.2wt%, 0.3wt%, 0.4wt%, 0.5wt%, 0.6wt%, 0.7wt%, 0.8wt%, 0.9wt%, 1.0wt% or any range therebetween.

[0089] In some embodiments of the present application, the cosmetic further comprises one or more of vegetable oil, silicone oil alternative grease, synthetic grease, antioxidant and anti - inflammatory agent.

[0090] In some embodiments of the present application, based on the total weight of the cosmetic, the vegetable oil is 0.01 to 10 wt%, for example, based on the total weight of the cosmetic, the vegetable oil can be 0.01 wt%, 0.05 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.0 wt%, 1.1 wt%, 1.2 wt%, 1.3 wt%, 1.4 wt%, 1.5 wt%, 1.6 wt%, 1.7 wt%, 1.8 wt%, 1.9 wt%, 2.0 wt%, 2.1 wt%, 2.2 wt%, 2.3 wt%, 2.4 wt%, 2.5 wt%, 2.6 wt%, 2.7 wt%, 2.8 wt%, 2.9 wt%, 3.0 wt%, 3.1 wt%, 3.2 wt%, 3.3 wt%, 3.4 wt%,  3.5 wt%, 3.6 wt%, 3.7 wt%, 3.8 wt%, 3.9 wt%, 4.0 wt%, 4.1 wt%, 4.2 wt%, 4.3 wt%, 4.4 wt%, 4.5 wt%, 4.6 wt%, 4.7 wt%, 4.8 wt%, 4.9 wt%, 5.0 wt%, 5.1 wt%, 5.2 wt%, 5.3 wt%, 5.4 wt%, 5.5 wt%, 5.6 wt%, 5.7 wt%, 5.8 wt%, 5.9 wt%, 6.0 wt%, 6.1 wt%, 6.2 wt%, 6.3 wt%, 6.4 wt%, 6.5 wt%, 6.6 wt%, 6.7 wt%, 6.8 wt%, 6.9 wt%, 7.0 wt%, 7.1 wt%, 7.2 wt%, 7.3 wt%, 7.4 wt%, 7.5 wt%, 7.6 wt%, 7.7 wt%, 7.8 wt%, 7.9 wt%, 8.0 wt%, 8.1 wt%, 8.2 wt%, 8.3 wt%, 8.4 wt%, 8.5 wt%, 8.6 wt%, 8.7 wt%, 8.8 wt%, 8.9 wt%, 9.0 wt%, 9.1 wt%, 9.2 wt%, 9.3 wt%, 9.4 wt%, 9.5 wt%, 9.6 wt%, 9.7 wt%, 9.8 wt%, 9.9 wt%, 10.0 wt% or any range therebetween.

[0091] In the present application, the vegetable oil is a vegetable oil with a refreshing skin feel, which can supplement skin lipids and enhance the skin barrier. In some embodiments, the vegetable oil includes Prinsepia utilis oil. Preferably, the vegetable oil further includes one or more of Vitis vinifera seed oil, Simmondsia chinensis seed oil, Limnanthes alba seed oil, Prunus amygdalus dulcis oil, and Prunus armeniaca kernel oil.

[0092] In some embodiments of the present application, based on the total weight of the cosmetic, the mass percentage of the Prinsepia utilis oil is 0.01 wt% to 2 wt%. For example, the mass percentage of the Prinsepia utilis oil can be 0.01 wt%, 0.05 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.0 wt%, 1.1 wt%, 1.2 wt%, 1.3 wt%, 1.4 wt%, 1.5 wt%, 1.6 wt%, 1.7 wt%, 1.8 wt%, 1.9 wt%, 2.0 wt% or any range therebetween.

[0093] In some embodiments of the present application, the silicone oil substitute for oil refers to "the oil substituting for silicone oil". Based on the total weight of the cosmetic, the silicone oil substitute for oil is 1 to 40 wt%. For example, the silicone oil substitute for oil can be 1 wt%, 2 wt%, 3 wt%, 4 wt%, 5 wt%, 6 wt%, 7 wt%, 8 wt%, 9 wt%, 10 wt%, 11 wt%, 12 wt%, 13 wt%, 14 wt%, 15 wt%, 16 wt%, 17 wt%, 18 wt%, 19 wt%, 20 wt%, 21 wt%, 22 wt%, 23 wt%, 24 wt%, 25 wt%, 26 wt%, 27 wt%, 28 wt%, 29 wt%, 30 wt%, 31 wt%, 32 wt%, 33 wt%, 34 wt%, 35 wt%, 36 wt%, 37 wt%, 38 wt%, 39 wt%, 40 wt% or any range therebetween.

[0094] In some embodiments of the present application, the silicone oil substitute for oil is selected from one or more of C9-12 alkane, C13-14 alkane, C13-15 alkane, C15-19 alkane, C15-23 alkane, C18-21 alkane, undecane, tridecane, and octadecane.

[0095] C9-12 alkanes, C13-14 alkanes, C13-15 alkanes, C15-19 alkanes, C15-23 alkanes, C18-21 alkanes, undecane, tridecane, and octadecane can be sourced from any company in the market as long as their functions are satisfied. Among them, undecane and tridecane are from BASF (China) Co., Ltd.

[0096] Ultimate; C15-19 alkane is from EMOGREEN L19 of SEPPIC S.A.

[0097] The silicone oil replacing the grease all shows a low-viscosity and light-textured feel similar to that of organosilicone oil.

[0098] In some embodiments of the present application, based on the total weight of the cosmetic, the synthetic oil is 38-98.5 wt%, for example, based on the total weight of the cosmetic, the synthetic oil can be 38 wt%, 39 wt%, 40 wt%, 41 wt%, 42 wt%, 43 wt%, 44 wt%, 45 wt%, 46 wt%, 47 wt%, 48 wt%, 49 wt%, 50 wt%, 51 wt%, 52 wt%, 53 wt%, 54 wt%, 55 wt%, 56 wt%, 57 wt%, 58 wt%, 59 wt%, 60 wt%, 61 wt%, 62 wt%, 63 wt%, 64 wt%, 65 wt%, 66 wt%, 67 wt%, 68 wt%, 69 wt%, 70 wt%, 71 wt%, 72 wt%, 73 wt%, 74 wt%, 75 wt%, 76 wt%, 77 wt%, 78 wt%, 79 wt%, 80 wt%, 81 wt%, 82 wt%, 83 wt%, 84 wt%, 85 wt%, 86 wt%, 87 wt%, 88 wt%, 89 wt%, 90 wt%, 91 wt%, 92 wt%, 93 wt%, 94 wt%, 95 wt%, 96 wt%, 97 wt%, 98 wt%, 98.5 wt% or any range therebetween.

[0099] In some embodiments of the present application, the synthetic oil is selected from one or more of diethylhexyl carbonate, dicaprylyl carbonate, coco-caprylate / caprate, butanediol dicaprylate / dicaprate, di-n-octyl ether, neopentyl glycol diheptanoate, and heptyl undecylenate.

[0100] In some embodiments of the present application, based on the total weight of the cosmetic, the antioxidant is 0.05 - 1.5 wt%, for example, it can be 0.05 wt%, 0.1 wt%, 0.2 wt%, 0.3 wt%, 0.4 wt%, 0.5 wt%, 0.6 wt%, 0.7 wt%, 0.8 wt%, 0.9 wt%, 1.0 wt%, 1.1 wt%, 1.2 wt%, 1.3 wt%, 1.4 wt%, 1.5 wt% or any range therebetween.

[0101] In some embodiments of the present application, the antioxidant is tocopherol (vitamin E) and / or tocopheryl acetate. The antioxidant is oily. In addition to preventing the oxidative deterioration of oils and fats, it can also protect cell membranes from being damaged by free radicals and resist the damage of external irritants to the skin.

[0102] In some embodiments of the present application, based on the total weight of the cosmetic, the anti-inflammatory agent is 0.01 - 0.26 wt%. For example, based on the total weight of the cosmetic, the anti-inflammatory agent is 0.01 wt%, 0.02 wt%, 0.03 wt%, 0.04 wt%, 0.05 wt%, 0.06 wt%, 0.07 wt%, 0.08 wt%, 0.09 wt%, 0.1 wt%, 0.11 wt%, 0.12 wt%, 0.13 wt%, 0.14 wt%, 0.15 wt%, 0.16 wt%, 0.17 wt%, 0.18 wt%, 0.19 wt%, 0.2 wt%, 0.21 wt%, 0.22 wt%, 0.23 wt%, 0.24 wt%, 0.25 wt%, 0.26 wt% or any range therebetween.

[0103] In some embodiments of the present application, the anti-inflammatory agent is stearyl glycyrrhetinate and / or bisabolol.

[0104] In the present application, the anti-inflammatory agent is oily. Due to the characteristics of damaged barrier function or abnormal nerve function in sensitive skin, it is more difficult to resist the invasion of external irritants and allergens compared with normal skin, and it is prone to a series of skin inflammatory reactions caused by irritation or allergy, which then further damage the skin barrier structure and nerve endings, leading to a vicious cycle. Thus, inflammation plays a very crucial role in common skin sensitivity problems. Adding anti-inflammatory ingredients, such as stearyl glycyrrhetinate and / or bisabolol, can reduce the entry of antigens into the skin and avoid the allergic reaction of normal cells, thereby accelerating the self-repair speed of the skin barrier and strengthening the resistance of the skin.

[0105] In the present application, the cosmetic is selected from one of essence oil and body care oil.

[0106] The cosmetics of the present application are of an oily system, with a relatively light texture, weak greasiness, and can comprehensively and effectively address sensitive skin problems. The addition of its efficacy composition makes it refreshing and non-greasy when in use.

[0107] The following further details the present application in conjunction with examples, but does not limit the scope of the present application.

[0108] Preparation Example 1

[0109] In the efficacy composition, all the combined components are oily liquids, and can be directly mixed evenly at room temperature according to the contents in Table 1.

[0110] In G1, take 1.5 g of 1609, 1.5 g of 100, 3 g of 0.5 g of Crithmum maritimum extract, wherein 1609, 100 and The mass ratio of is 3:3:6, The mass ratio of 1609 and Crithmum maritimum extract is 3:1, thus obtaining the efficacy composition G1.

[0111] In G2, take 1.5 g of 1609, 1.5 g of 100, 1.5 g of 0.5 g of Crithmum maritimum extract, wherein 1609, 100 and The mass ratio of is 3:3:3, The mass ratio of 1609 and Crithmum maritimum extract is 3:1, thus obtaining the efficacy composition G2.

[0112] In G3, take 1.5 g of 1609, 1.5 g of 100, 3 g of 1.5 g of Crithmum maritimum extract, wherein 1609, 100 and The mass ratio of is 3:3:6, The mass ratio of 1609 and Crithmum maritimum extract is 1:1, thus obtaining the efficacy composition G3. In G4, take 0.1 g of 1609, 0.1 g of 100, 0.2 g of 0.1 g of Crithmum maritimum extract, wherein 1609, 100 and have a mass ratio of 3:3:6, 1609 and the Crithmum maritimum extract have a mass ratio of 1:1, thus obtaining the efficacy composition G4.

[0113] In G5, take 1.5 g of 1609, 1.5 g of 100, 3 g of wherein 1609, 100 and have a mass ratio of 3:3:6, thus obtaining the efficacy composition G5.

[0114] In G6, different from G1, 3 g of phytosteryl oleate is used to replace The rest is the same as G1, thus obtaining the efficacy composition G6.

[0115] In G7, different from G1, 1.5 g of phytosteryl oleate is used to replace 100, and the rest is the same as G1, thus obtaining the efficacy composition G7.

[0116] In G8, take 1.5 g of 100, 3 g of 0.5 g of Crithmum maritimum extract, wherein 100 and have a mass ratio of 3:6, thus obtaining the efficacy composition G8.

[0117] In G9, take 1.5 g of 1609, 3 g of 0.5 g of Crithmum maritimum extract, wherein 1609 and have a mass ratio of 3:6, 1609 and the Crithmum maritimum extract have a mass ratio of 3:1, thus obtaining the efficacy composition G9.

[0118] In G10, take 1.5 g of 1609, 1.5 g of 100, 0.5 g of Crithmum maritimum extract, wherein 1609, The mass ratio of 100 is 3:3, The mass ratio of 1609 and Crithmum maritimum extract is 3:1, and the efficacy composition G10 is obtained.

[0119] Table 1 Efficacy composition

[0120]

[0121]

[0122] In the preparation of the essential oil, each component is an oily liquid or an oil-soluble powder. Under stirring conditions, each component is added in sequence according to the content of each component in Table 2 (it is recommended to add synthetic grease and silicone oil to replace grease first for convenient stirring), and after stirring evenly, the essential oil can be obtained.

[0123] Example 1

[0124] Take 20 g of C15-19 alkane, 33.795 g of butanediol dicaprylate / dicaprate and 33.795 g of coco alcohol-caprylate / caprate, and then add 6.5 g of efficacy composition G1, 1 g of Prinsepia utilis oil, 4 g of Prunus amygdalus dulcis oil, 0.8 g of tocopherol (vitamin E), 0.01 g of stearyl glycyrrhetinate and 0.1 g of bisabolol in sequence, and stir evenly to obtain the essential oil.

[0125] Example 2

[0126] The difference between Example 2 and Example 1 is only that the efficacy composition is G2, and 6.5 g is taken according to the proportion of G2, and the rest is the same as Example 1.

[0127] Example 3

[0128] The difference between Example 3 and Example 1 is only that the efficacy composition is G3, and 6.5 g is taken according to the proportion of G3, and the rest is the same as Example 1.

[0129] Example 4

[0130] The difference between Example 4 and Example 1 is only that the efficacy composition is G4, and 6.5 g is taken according to the proportion of G4, and the rest is the same as Example 1.

[0131] Example 5

[0132] The difference between Example 5 and Example 1 is only that the efficacy composition is G5, and 6.5 g is taken according to the proportion of G5, and the rest is the same as Example 1.

[0133] Example 6

[0134] Example 6 is only different from Example 1 in that the efficacy composition is G6, and 6.5 g is taken according to the proportion of G6, and the rest is the same as Example 1.

[0135] Example 7

[0136] Example 7 is only different from Example 1 in that the efficacy composition is G7, and 6.5 g is taken according to the proportion of G7, and the rest is the same as Example 1.

[0137] Comparative Example 1

[0138] Comparative Example 1 is only different from Example 1 in that the efficacy composition is G8, and 6.5 g is taken according to the proportion of G8, and the rest is the same as Example 1.

[0139] Comparative Example 2

[0140] Comparative Example 2 is only different from Example 1 in that the efficacy composition is G9, and 6.5 g is taken according to the proportion of G9, and the rest is the same as Example 1.

[0141] Comparative Example 3

[0142] Comparative Example 3 is only different from Example 1 in that the efficacy composition is G10, and 6.5 g is taken according to the proportion of G10, and the rest is the same as Example 1.

[0143] Table 2 (taking 100 g of the total weight of the cosmetic as an example)

[0144]

[0145]

[0146] Verification of skin feel and efficacy

[0147] Experimental Example 1 Skin feel evaluation

[0148] First, 30 healthy female subjects were randomly selected, with an age range of 18 - 60 years old. Then, the essence oil products corresponding to Examples 1 - 7 and Comparative Examples 1 - 3 were distributed to the subjects, 2 - 3 drops at a time, used twice a day, morning and evening, and each product was used continuously for three days. After using the products, the skin feel evaluations of the five essence oil products corresponding to Examples 1 - 7 and Comparative Examples 1 - 3 were carried out respectively. The skin feel evaluation was mainly for the texture of the essence oil (acceptance of greasiness). The evaluation results of the 30 volunteers are as follows in Table 1 (<6 points, dissatisfied; 6 - 8 points, acceptable; >8 points, satisfied)

[0149] Table 3. Evaluation of greasiness satisfaction

[0150]

[0151]

[0152] In the greasiness satisfaction evaluation form of Table 3, the greater the average acceptance of the essence oil product by 30 volunteers, that is, the higher the acceptance, the weaker the greasiness of the corresponding essence oil product, and the fresher the skin feeling. It can be seen from Table 3 above that compared with Comparative Examples 1-3, the greasiness of the essence oil products of Examples 1-7 is reduced a lot.

[0153] 2. Transdermal water loss test of the skin

[0154] Thirty-three healthy female subjects with sensitive skin type and dry and water-deficient skin on the flexor side of the forearm, aged 18 to 60 years old, were selected. Equal amounts (2 mL / cm 2 ) of the essence oils prepared in Examples 1-7 and Comparative Examples 1-3 were applied to different areas on the flexor side of the subjects' forearms, once in the morning and once in the evening, for 4 consecutive weeks. During the period of using the product, no other skin care products were used. The transdermal water loss of the subjects before using the product, 14 days after using the product, and 28 days after using the product was measured with a skin water loss tester Tewameter TM 300.

[0155] Table 4. Evaluation of transdermal water loss

[0156]

[0157]

[0158] The transdermal water loss rate is closely related to the skin barrier function. The lower the transdermal water loss rate, the better the skin barrier function, indicating that the product has a better ability to repair the skin barrier. It can be seen from Table 4 that after using the product for 28 days, the transdermal water loss of Examples 1-5 is less than that of Examples 6-7 and Comparative Examples 1-3, that is, the loss of skin water is less, indicating that the repair effect of this essence oil product is better. Thus, it can be seen that the efficacy composition helps to reduce the transdermal water loss rate in the system. The transdermal water loss rates of Comparative Example 1, Comparative Example 2, and Comparative Example 3 are higher than that of Example 1. 1609, 100, and all have a certain impact on the reduction of the transdermal water loss rate. Comparing Example 1, Example 3, and Example 5, the auxiliary efficacy substances are also helpful for reducing the transdermal water loss rate of the essence oil product.

[0159] 3. Self-evaluation by subjects

[0160] Thirty healthy female subjects with sensitive skin, dry and water-deficient skin, and damaged barrier function were selected. The essence oil obtained from Example 1 was distributed for trial use, once in the morning and once in the evening, 2-3 drops each time, for 14 consecutive days. Then the subjects were asked to fill in the evaluation questionnaire, and the statistical results are shown in Table 5:

[0161]

[0162] It can be seen from the self-evaluation of the subjects in the above table that Example 1 has good moisturizing effect and anti-allergy and repair effect on the skin. Moreover, the product has good mildness and high overall satisfaction.

[0163] The above embodiments may be preferred embodiments of the present invention, but the embodiments of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications made without departing from the spirit and principle of the present invention shall be equivalent replacement methods and are all included in the protection scope of the present invention.

Claims

1. An efficacy composition for essence oil or body care oil, wherein, Comprising: SymSitive® 1609, SymRepair® 100 and L22®; Relative to 1 part by weight of the SymSitive® 1609, the SymRepair® 100 is 0.25 to 1 part by weight, and the L22® is 1.5 to 2.5 parts by weight; The efficacy composition further comprises an auxiliary efficacy agent, wherein the auxiliary efficacy agent is Crithmum maritimum extract, and relative to 1 part by weight of the SymSitive® 1609, the Crithmum maritimum extract is 0.2 to 0.5 part by weight.

2. Use of the efficacy composition according to claim 1 in the preparation of essence oil and body care oil.

3. A cosmetic, wherein, It comprises the efficacy composition according to claim 1.

4. The cosmetic according to claim 3, wherein, Based on the total weight of the cosmetic, the mass percentage of the efficacy composition is 0.5 to 10 wt%.

5. The cosmetic according to claim 4, wherein, Based on the total weight of the cosmetic, the mass percentage of the SymSitive® 1609 is 0.01 to 3 wt%, the mass percentage of the SymRepair® 100 is 0.01 to 3 wt%, the mass percentage of the L22® is 0.1 to 3 wt%, and the mass percentage of the auxiliary efficacy agent is 0.01 to 1 wt%.

6. The cosmetic according to claim 5, wherein, The cosmetic further comprises one or more of vegetable oil, silicone oil alternative grease, synthetic grease, antioxidant and anti-inflammatory agent.

7. The cosmetic according to claim 6, wherein, Based on the total weight of the cosmetic, the vegetable oil is 0.01 to 10 wt%, the silicone oil alternative grease is 1 to 40 wt%, the synthetic grease is 38 to 98.5 wt%, the antioxidant is 0.05 to 1.5 wt%, and the anti-inflammatory agent is 0.01 to 0.26 wt%.

8. The cosmetic according to claim 6, wherein, The vegetable oil includes Prinsepia utilis Royle oil.

9. The cosmetic according to claim 8, wherein, The vegetable oil further includes one or more of grape seed oil, jojoba seed oil, Limnanthes alba (Meerb.) Benth. seed oil, sweet almond oil, almond oil.

10. The cosmetic according to claim 8, wherein, Based on the total weight of the cosmetic, the mass percentage of the Prinsepia utilis Royle oil is 0.01 wt% to 2 wt%.

11. The cosmetic according to claim 6 or 7, wherein, The silicone oil alternative grease is selected from one or more of C9-12 alkanes, C13-14 alkanes, C15-23 alkanes; or The synthetic grease is selected from one or more of diethylhexyl carbonate, dicapryl carbonate, coco alcohol caprylate / caprate, butanediol dicaprylate / dicaprate, dioctyl ether, neopentyl glycol diheptanoate, heptyl undecylenate.

12. The cosmetic according to claim 6 or 7, wherein, The antioxidant is tocopherol and / or tocopheryl acetate; or The anti-inflammatory agent is stearyl glycyrrhetinate and / or bisabolol.

13. The cosmetic according to any one of claims 3 to 10, wherein the cosmetic is selected from one of essence oil and body care oil.

Images