Molybdenum-rhenium alloy bone plate system with growth stimulation function

Abstract

The application provides a molybdenum-rhenium alloy bone plate system with a growth stimulating function, and belongs to the technical field of trauma surgery instruments. The bone growth stimulating mechanism is arranged on one side of the bone plate body facing the bone surface through the micro self-adaptive lifting mechanism, and the pressure value between the bone growth stimulating mechanism and the bone surface is automatically adjusted by the control module, so that the electrode unit of the bone growth stimulating mechanism can be stably attached to the trauma surface without affecting the blood supply, the trauma bone surface is continuously and stably stimulated by direct current, the activity of osteoblast proliferation is promoted, and bone healing is accelerated.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of trauma surgical instruments, in particular to a molybdenum-rhenium alloy bone plate system with growth stimulation function. BACKGROUND

[0002] Traumatic fracture healing is an extremely complex biological process, which is affected by micro-motion, blood supply and stress. In the normal healing process of fracture, it can be divided into primary healing and secondary healing. When rigid internal fixation and external fixation are performed on the fracture, primary healing of the fracture can occur; during the primary healing process, no internal and external callus is generally formed. When non-rigid internal fixation is performed on the fracture, i.e. the fracture ends have relative movement, local external callus (cortical bone surface) and internal callus (intramedullary, between fracture ends) are formed, i.e. the mode of secondary healing of fracture, which is currently generally considered to be more conducive to fracture repair.

[0003] At present, locking bone plates are widely used in the treatment of fractures. Since there is an angle stability interface between the screw and the bone plate, the bone plate can be placed without contacting the bone, so they are considered as internal fixation frames from the perspective of biomechanics. In view of the inherent advantages of locking bone plates in biomechanics, they can provide more stable fixation for osteoporotic fractures, comminuted fractures and periarticular fractures. However, after the fracture is fixed, the locking screw and the steel plate are tightly combined, so the stress and micro-motion generated by the fracture ends are small and asymmetric, the stress and micro-motion of the fracture end near the steel plate are small, while the stress and micro-motion of the opposite side of the steel plate are relatively large, resulting in asymmetric callus formation, which leads to complications such as internal fixation failure, delayed healing and non-union of the fracture after LCP fixation.

[0004] In the prior art, a bone plate is used in combination with an electric stimulation structure to stimulate bone growth. The electric stimulation structure is generally fixed on the bone plate, which increases the volume of the bone plate and makes the foreign body sensation more obvious after implantation. In addition, as the bone grows and the body moves, the electric stimulation structure may not be in good contact with the bone surface, resulting in poor stimulation growth effect. At the same time, bone growth can increase the contact pressure between the electric stimulation structure and the bone surface, which affects the blood supply of the trauma site and is not conducive to recovery. SUMMARY

[0005] The task of the present application is to provide a bone plate system that can be used as an internal fixation implant and can accelerate the healing of fractures in the treatment of traumatic fractures.

[0006] The technical problem to be solved by the present application is how to solve the possible healing failure and internal fixation failure in the process of using a bone plate as an internal fixation implant to treat traumatic fractures, and to accelerate the healing speed of the fracture, avoid internal fixation failure, and reduce the pain of the patient.

[0007] To solve the above technical problems, the purpose of the present application is achieved as follows:

[0008] A molybdenum-rhenium alloy bone plate system with growth stimulation function, characterized in that it comprises a bone plate body, a bone growth stimulation mechanism, a micro self-adaptive lifting mechanism, a control module and a power module.

[0009] The bone growth stimulation mechanism is arranged on the side of the bone plate body facing the bone surface and is attached to the bone surface.

[0010] The micro self-adaptive lifting mechanism is arranged between the bone growth stimulation mechanism and the bone plate body and can adjust the distance between the bone growth stimulation mechanism and the bone plate body.

[0011] The control module is arranged on the bone plate body and is electrically connected to the bone growth stimulation mechanism and the micro self-adaptive lifting mechanism for controlling the bone growth stimulation mechanism and the micro self-adaptive lifting mechanism.

[0012] The power module is arranged on the bone plate body for power supply.

[0013] On the basis of the above scheme and as a preferred scheme of the above scheme, the bone plate body is provided with extension side plates on both sides; the extension side plates include a circular mounting plate, a strip-shaped support plate and an auxiliary component mounting plate; the strip-shaped support plate is connected to the bone plate body and the circular mounting plate at both ends respectively; the auxiliary component mounting plate is connected to the side of the circular mounting plate; the micro self-adaptive lifting mechanism is installed below the circular mounting plate, and the bone growth stimulation mechanism is installed below the micro self-adaptive lifting mechanism; the control module is installed above the circular mounting plate; and the power module is installed on the auxiliary component mounting plate.

[0014] On the basis of the above scheme and as a preferred scheme of the above scheme, the extension side plates and the bone plate body are integrally formed and are made of molybdenum-rhenium alloy material.

[0015] On the basis of the above scheme and as a preferred scheme of the above scheme, the micro self-adaptive lifting mechanism comprises a double-joint connecting rod, a piezoelectric actuator, a pressure-sensitive sensing film, an upper fixing plate and a lower base plate; the upper fixing plate is fixedly connected below the circular mounting plate; the lower base plate is connected to the upper fixing plate through a plurality of groups of double-joint connecting rods; the piezoelectric actuator is fixedly arranged on the bottom surface of the upper fixing plate and drives the double-joint connecting rods to move as a driving force source; and the pressure-sensitive sensing film is arranged on the bottom surface of the lower base plate and serves as a force signal collector.

[0016] On the basis of the above scheme and as a preferred scheme of the above scheme, the piezoelectric actuator is composed of a thin layer of piezoelectric ceramic and is fixedly connected to one end of the double-link rod; the upper fixed plate and the lower base plate are both made of ultra-high molecular polyethylene, and the double-link rod is made of molybdenum-rhenium alloy; and the pressure-sensitive sensing film is a circular ring-shaped sheet and is packaged and sealed by upper and lower films.

[0017] On the basis of the above scheme and as a preferred scheme of the above scheme, the bone growth stimulating mechanism comprises stimulating pieces, insulating medical silica gel and a constant current generator; the insulating medical silica gel is arranged below the lower base plate; the stimulating pieces are evenly distributed on the bottom surface of the insulating medical silica gel; and the constant current generator is integrated in the control module and is electrically connected to the stimulating pieces.

[0018] On the basis of the above scheme and as a preferred scheme of the above scheme, the stimulating pieces are made of pure titanium and have a plurality of point-shaped bone growth stimulating units evenly distributed on the bottom surface.

[0019] On the basis of the above scheme and as a preferred scheme of the above scheme, the electrical connection adopts wire connection; and the wire is a stainless steel-silver stranded wire and is coated with silica gel on the outer layer.

[0020] On the basis of the above scheme and as a preferred scheme of the above scheme, the control module and the power module are both externally covered with a medical-grade titanium shell.

[0021] On the basis of the above scheme and as a preferred scheme of the above scheme, the control module comprises a DSP, a signal acquisition unit and an actuator control unit; the pressure value detected by the pressure-sensitive sensing film is transmitted to the DSP through the signal acquisition unit, and the DSP automatically controls the actuator control unit to make the piezoelectric actuator generate movement and control the pressure between the stimulating pieces and the bone surface to reach a predetermined value.

[0022] The present application has the following beneficial effects:

[0023] 1. The present application automatically judges whether the electrode unit of the bone growth stimulating structure is in effective contact with the underlying tissue through the force signal collected by the pressure-sensitive sensing film, controls the lower base plate to move up and down and left and right through the power source of the piezoelectric actuator, so that the bone growth stimulating structure can stably contact the wound site, and automatically adjusts the contact force value through the control module, so that the pressure value between the bone growth stimulating structure and the wound site remains constant, thereby avoiding the influence of bone growth extrusion of the bone plate on the blood supply of the wound.

[0024] 2, through the constant current generator to stimulate the power supply, through the stimulation of the wound site to provide sustained current stimulation, help bone growth, accelerate the healing rate of fracture. With the growth of the trauma site and the movement of the human body, the micro self-adaptive lifting structure can automatically adjust, so that the stimulating piece can stably adhere to the wound site with the same contact force value.

[0025] 3, the bone plate body adopts molybdenum rhenium alloy material, compared with the traditional titanium alloy bone plate, but the strength, hardness and other mechanical properties are obviously improved, the bone plate system composed of the whole will not cause additional foreign body sensation, and the safety and reliability are higher after implantation. BRIEF DESCRIPTION OF DRAWINGS

[0026] Figure 1 The structure of the present application is shown in the figure.

[0027] Figure 2 The structure of the present application is shown in the figure.

[0028] Figure 3 The structure of the present application is shown in the figure.

[0029] Figure 4 The structure of the present application is shown in the figure.

[0030] Figure 5 The structure of the present application is shown in the figure.

[0031] Figure 6 The structure of the present application is shown in the figure.

[0032] Figure 7 The structure of the present application is shown in the figure.

[0033] Figure 8 The structure of the present application is shown in the figure.

[0034] In the figure: 1, the bone plate body; 2, the bone growth stimulating mechanism; 21, the stimulating piece; 22, the insulating medical silica gel; 3, the micro self-adaptive lifting mechanism; 31, the double joint connecting rod; 32, the piezoelectric actuator; 33, the pressure sensitive sensing film; 34, the upper fixed plate; 35, the lower base plate; 4, the control module; 5, the power module; 6, the extension side plate; 61, the circular mounting plate; 62, the strip support plate; 63, the auxiliary mounting plate. DETAILED DESCRIPTION

[0035] The present application will be further described below in conjunction with the drawings and specific examples.

[0036] As Figures 1 to 5As shown, a molybdenum-rhenium alloy bone plate system with growth stimulation function comprises a bone plate body 1, a bone growth stimulation mechanism 2, a micro self-adaptive lifting mechanism 3, a control module 4 and a power module 5. After the bone plate body 1 is installed and fixed at the trauma site, the system can automatically control the movement of the lifting structure under power supply, achieve stable contact between the bottom bone growth stimulation stimulating piece and the trauma site, and continuously release direct current through the stimulating piece to stimulate bone growth, callus formation and accelerate bone remodeling.

[0037] The bone growth stimulation mechanism 2 is arranged on the side of the bone plate body 1 facing the bone surface and is attached to the bone surface, used for electrically stimulating bone growth.

[0038] The micro self-adaptive lifting mechanism 3 is arranged between the bone growth stimulation mechanism 2 and the bone plate body 1, which can adjust the distance between the bone growth stimulation mechanism 2 and the bone plate body 1, and is used for adjusting the pressure value between the bone growth stimulation mechanism 2 and the bone surface.

[0039] The control module 4 is fixedly arranged on the bone plate body 1 and is electrically connected with the bone growth stimulation mechanism 2 and the micro self-adaptive lifting mechanism 3, which is used for controlling the bone growth stimulation mechanism 2 and the micro self-adaptive lifting mechanism 3.

[0040] The power module 5 is fixedly arranged on the bone plate body 1 and is used for supplying power to the bone growth stimulation mechanism 2, the micro self-adaptive lifting mechanism 3 and the control module 4.

[0041] The bone plate body 1 is provided with extension side plates 6 on both sides, which are used for fixedly connecting the bone growth stimulation mechanism 2, the micro self-adaptive lifting mechanism 3, the control module 4 and the power module 5.

[0042] The extension side plate comprises a circular mounting plate 61, a strip-shaped support plate 62 and an auxiliary component mounting plate 63. The strip-shaped support plate 62 is connected with the bone plate body 1 and the circular mounting plate 61 at both ends respectively, and the auxiliary component mounting plate 63 is connected to the side of the circular mounting plate 61. Preferably, the number of strip-shaped support plates 62 is two, and a space is arranged between the two strip-shaped support plates 62, and the auxiliary component mounting plate 63 is arranged in the space.

[0043] The micro self-adaptive lifting mechanism 3 is installed below the circular mounting plate 61, the bone growth stimulation mechanism 2 is installed below the micro self-adaptive lifting mechanism 3, and the control module 4 is installed above the circular mounting plate 61; the power module 5 is installed on the auxiliary component mounting plate 63. The control module 4 and the power module 5 are both covered with a medical-grade titanium shell outside to protect the control module 4 and the power module 5. A wire hole is arranged in the middle of the circular mounting plate 61 to pass the wire, realizing the electrical connection between the control module 4 and the bone growth stimulation mechanism 2 and the micro self-adaptive lifting mechanism 3.

[0044] Further, the extension side plate 6 is integrally formed with the bone plate body 1 and is made of molybdenum-rhenium alloy. The bone plate body 1 made of molybdenum-rhenium alloy is lighter and thinner than the traditional titanium alloy bone plate, but the mechanical properties such as strength and hardness are significantly improved. The overall bone plate system does not cause additional foreign body sensation, and due to its stronger mechanical properties, it will have safer and more reliable performance after being implanted in the body.

[0045] As shown in Figure 6 and Figure 7 , the micro self-adaptive lifting mechanism 3 includes double-link 31, piezoelectric actuator 32, pressure-sensitive sensing diaphragm 33, upper fixed plate 34 and lower base plate 35. The overall structure is adhered to the circular mounting plate 61 by medical adhesive. The overall motion structure constitutes a parallel form. The force signal collected by the pressure-sensitive sensing diaphragm 33 automatically determines whether the electrode unit of the bone growth stimulation mechanism 2 is in effective contact with the tissue below. Through the power source of the piezoelectric actuator 32, the lower base plate 35 can move up and down and left and right, so that the bone growth stimulation structure can stably contact the wound site, and the contact force value is automatically adjusted to avoid affecting the blood supply of the wound.

[0046] The upper fixed plate 34 is fixedly connected below the circular mounting plate 61; the lower base plate 35 is connected with the upper fixed plate 34 through a plurality of groups of double-link 31. Preferably, the upper fixed plate 34 and the lower base plate 35 are circular and are made of ultra-high molecular polyethylene, and a wiring hole is formed in the middle. A plurality of groups of double-link 31 are evenly distributed along the circumference of the circular upper fixed plate 34, including two hinged together links, and the other end of the link is hinged with the upper fixed plate 34 and the lower base plate 35. Preferably, the double-link 31 is made of molybdenum-rhenium alloy, and the mirror surface of the rotating joint contact part is polished by abrasive flow to reduce friction and wear, and rotation is more flexible.

[0047] The piezoelectric actuator 32 is fixedly arranged on the bottom surface of the upper fixed plate 34, one end of which is fixedly connected with the double-link 31 to drive the double-link 31 to move as a power source. The movement of the piezoelectric actuator 32 drives the rotation of the double-link 31, achieving the effect of controlling the movement of the lower base plate 35. Specifically, the piezoelectric actuator 32 is composed of a thin layer of piezoelectric ceramic.

[0048] The pressure-sensitive sensing diaphragm 33 is arranged on the bottom surface of the lower base plate 35 as a force signal collector. Preferably, the pressure-sensitive sensing diaphragm 33 is a circular ring-shaped sheet, which is packaged and sealed to protect the pressure-sensitive sensing diaphragm 33.

[0049] As shown in Figure 6 and Figure 7As shown, the bone growth stimulating mechanism 2 includes stimulating pieces 21, insulating medical silica gel 22 and a constant current generator. The insulating medical silica gel 22 is arranged below the lower substrate 35, and the stimulating pieces 21 are arranged on the bottom surface of the insulating medical silica gel 22.

[0050] The insulating medical silica gel 22 is used to absorb the fluctuation of force, so as to avoid the impact force generated suddenly from affecting the body tissue or the micro self-adaptive lifting mechanism 3. Preferably, the insulating medical silica gel 22 is in the form of a round sheet.

[0051] The stimulating pieces 21 stimulate the bone growth by electric current. Preferably, the stimulating pieces 21 are made of pure titanium, and the bottom surface is uniformly provided with a plurality of point-shaped bone growth stimulating units. The point-shaped bone growth stimulating units are made of platinum gold coated on the bottom surface of the stimulating pieces 21.

[0052] The electric connection is achieved by a wire, which is a stainless steel-silver stranded wire coated with a silica gel insulation layer, and the wire is permanently connected by fusion titanium pressure bonding.

[0053] As shown, Figure 8 The control module 4 includes a DSP, a signal acquisition unit and an actuator control unit.

[0054] After the bone plate is implanted and locked and fixed, the power module 5 starts to supply power, the force value detected by the pressure-sensitive sensing diaphragm 33 is transmitted to the DSP through the signal acquisition unit, and the piezoelectric actuator 32 is controlled by the DSP to generate movement, so that the micro self-adaptive lifting mechanism 3 generates up and down movement, so as to promote the stimulating pieces 21 to have a certain contact pressure with the body tissue, but will not affect the blood supply of the wound. When the set pre-pressure value is reached, the micro self-adaptive lifting mechanism 3 stops moving, and the stimulating pieces 21 are powered by the constant current generator, and the stimulating pieces 21 provide continuous current stimulation to the wound. With the growth of the wound site and the movement of the human body, the micro self-adaptive lifting mechanism 3 can automatically adjust, so that the stimulating pieces 21 can stably adhere to the wound with the same contact force value.

[0055] Before the operation, a three-dimensional model is established by CT scanning of the wound of the patient, and a suitable bone plate shape is designed. The spherical molybdenum-rhenium alloy powder is used for 3D printing profiling, so as to obtain a bone plate body 1 and an extension side plate integrated with the bone plate body 1, which have high material precision and surface quality.

[0056] The preferred embodiments of the present application have been described above in detail. It should be understood that modifications and variations to the preferred embodiments could be made by those skilled in the art in light of the teachings above without departing from the spirit of the present application. It is therefore to be understood that what is desired to be protected by letters patent is defined by the scope of the claims that follow and that on behalf of which the summary of the application is intended to serve.

Claims

1. A molybdenum-rhenium alloy bone plate system having a growth stimulating function, characterized by, The application relates to a bone plate body (1), a bone growth stimulating mechanism (2), a micro self-adaptive lifting mechanism (3), a control module (4) and a power module (5). The bone growth stimulating mechanism (2) is arranged on the side of the bone plate body (1) facing the bone surface and is attached to the bone surface. The micro self-adaptive lifting mechanism (3) is arranged between the bone growth stimulating mechanism (2) and the bone plate body (1) and can adjust the distance between the bone growth stimulating mechanism (2) and the bone plate body (1). The control module (4) is arranged on the bone plate body (1) and is electrically connected with the bone growth stimulating mechanism (2) and the micro self-adaptive lifting mechanism (3) and is used for controlling the bone growth stimulating mechanism (2) and the micro self-adaptive lifting mechanism (3). The power module (5) is arranged on the bone plate body (1) and is used for power supply. The bone plate body (1) is provided with extension side plates (6) on both sides; the extension side plate comprises a circular mounting plate (61), a strip-shaped supporting plate (62) and an auxiliary component mounting plate (63); the strip-shaped supporting plate (62) is connected with the bone plate body (1) and the circular mounting plate (61) at two ends respectively; the auxiliary component mounting plate (63) is connected to the side of the circular mounting plate (61); the micro self-adaptive lifting mechanism (3) is installed below the circular mounting plate (61); the bone growth stimulating mechanism (2) is installed below the micro self-adaptive lifting mechanism (3); the control module (4) is installed above the circular mounting plate (61); and the power module (5) is installed on the auxiliary component mounting plate (63). The micro self-adaptive lifting mechanism (3) comprises double-link connecting rods (31), a piezoelectric actuator (32), a pressure-sensitive sensing diaphragm (33), an upper fixed plate (34) and a lower base plate (35); the upper fixed plate (34) is fixedly connected below the circular mounting plate (61); the lower base plate (35) is connected with the upper fixed plate (34) through a plurality of groups of double-link connecting rods (31); the piezoelectric actuator (32) is fixedly arranged on the bottom surface of the upper fixed plate (34) and drives the double-link connecting rods (31) to move; and the pressure-sensitive sensing diaphragm (33) is arranged on the bottom surface of the lower base plate (35) and serves as a force signal collector. The bone growth stimulating mechanism (2) comprises stimulating pieces (21), insulating medical silica gel (22) and a constant current generator; the insulating medical silica gel (22) is arranged below the lower base plate (35); the stimulating pieces (21) are evenly distributed on the bottom surface of the insulating medical silica gel (22); and the constant current generator is integrated in the control module (4) and is electrically connected with the stimulating pieces (21). The control module (4) comprises a DSP, a signal acquisition unit and an actuator control unit; the pressure value detected by the pressure-sensitive sensing diaphragm (33) is transmitted to the DSP through the signal acquisition unit, the DSP automatically controls the actuator control unit to make the piezoelectric actuator move and controls the pressure between the stimulating pieces (21) and the bone surface to reach a predetermined value. ​ 2. The molybdenum-rhenium alloy bone plate system with growth stimulation function according to claim 1, characterized in that, The extension side plate (6) is integrally formed with the bone plate body (1) and is made of molybdenum-rhenium alloy material.

3. The molybdenum-rhenium alloy bone plate system with growth stimulation function according to claim 1, characterized in that, The piezoelectric actuator (32) is composed of a thin layer of piezoelectric ceramic and is fixedly connected to one end of the double-link rod (31); the upper fixed plate (34) and the lower base plate (35) are both made of ultrahigh molecular polyethylene material, and the double-link rod (31) is made of molybdenum-rhenium alloy material; the pressure-sensitive sensing diaphragm (33) is a circular ring-shaped sheet and is sealed by upper and lower film packaging.

4. The molybdenum-rhenium alloy bone plate system with growth stimulation function according to claim 1, characterized in that, The stimulating sheet (21) is made of pure titanium material and is uniformly provided with a plurality of point-shaped bone growth stimulating units on the bottom surface.

5. The molybdenum-rhenium alloy bone plate system with growth stimulation function according to any one of claims 1-4, characterized in that, The electric connection adopts wire connection; the wire is stainless steel-silver stranded wire and is coated with silica gel on the outer layer.

6. The molybdenum-rhenium alloy bone plate system with growth stimulation function according to any one of claims 1-4, characterized in that, The control module (4) and the power module (5) are both externally covered with a medical-grade titanium shell.

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