A raw material screening device for gene drug research and development

By improving the design of the feeding and conveying mechanisms, the problems of powdered raw materials scattering and clumping during the screening process were solved, achieving efficient raw material dispersion and conveying, and improving the screening accuracy of the raw material screening device for gene drug development.

CN116571444BActive Publication Date: 2025-11-28FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202310568283.9
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-05-19
Publication Date
2025-11-28
Estimated Expiration
2043-05-19

AI Technical Summary

Technical Problem

Existing screening devices for raw materials used in gene drug development often result in powdered raw materials scattering and clumping, causing blockage of the sieve holes and reducing screening accuracy.

Method used

The design combines a feeding mechanism, a dispersing mechanism, a conveying mechanism, and a scraping mechanism. It includes an electric shaft, a pulley, a conveying threaded rod, a scraping mechanism, and a conveying mechanism. The motor is installed on the lower left side of the material cylinder. The pulley is connected to the motor and the conveying threaded rod. The conveying belt is connected to the pulley. The conveying threaded rod is installed on the lower inside of the material cylinder. There are six scraping mechanisms, which are symmetrically installed vertically. The scraper has a "U" shaped cross-section. The fixed rod cooperates with the spring tube sleeve to scrape off powder residue.

Benefits of technology

It effectively prevents powdery raw materials from drifting out and clumping, improves screening accuracy, ensures that raw materials smoothly enter the screening machine for dispersion and conveying, avoids blockage, and improves screening effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a raw material screening device for gene medicine research and development, which comprises a feeding inlet, a material cylinder, a torsion shaft, an opening and closing plate, a dispersion mechanism and a conveying mechanism. The feeding inlet is embedded in the middle end of the top of the material cylinder and is connected in penetration. The upper end in the interior of the material cylinder is hinged to the upper end outside of the opening and closing plate through the torsion shaft. The powder raw material is put into the interior of the material cylinder from the feeding inlet. After the completion of the putting, the opening and closing plate is automatically reset under the action of the reset elastic force of the torsion shaft, so that the feeding inlet is closed, and the powder is prevented from floating upward and floating out of the interior of the feeding inlet again. The rotation of the electric rotating shaft makes the two cams oppositely lift and lower the left and right ends of the bottom of the swing mechanism, so that the swing mechanism swings and contacts the powder raw material. The dispersion rod effectively disperses the powder raw material, avoids the phenomenon that the powder raw material is clumped, prevents the powder raw material from being treated as impurities, and improves the screening precision.
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Description

TECHNICAL FIELD

[0001] The application relates to the field of medicine research, in particular to a raw material screening device for gene medicine research. BACKGROUND

[0002] The gene medicine is closely related to the development of genetic engineering technology, the genetic engineering technology is the main body of modern biotechnology, and is mainly applied to molecular genetics, biology, medicine, pharmacy and other disciplines, and the raw material screening device needs to be used to screen the raw materials during the development of the gene medicine, however, during the screening of the powder-like gene medicine by the raw material screening device, the powder has the characteristics of floating and clumping, the powder-like raw materials are prone to floating out of the feeding port after entering the raw material screening device, and the clumped powder-like raw materials are difficult to screen, so that the clumped powder-like raw materials are prone to being blocked on the screen holes of the screen plate and are treated as impurities, thereby reducing the screening precision of the powder-like raw materials. SUMMARY

[0003] The technical scheme for achieving the technical purpose is that the raw material screening device for gene medicine research comprises a feeding mechanism, a screening machine, a support frame and a discharge port, the feeding mechanism is installed at the right end of the screening machine, the bottom of the screening machine is welded with the support frame, and the discharge port is embedded in the bottom of the screening machine and is connected in a penetrating mode.

[0004] As a further improvement of the application, the feeding mechanism comprises a feeding port, a barrel, a torsion shaft, an opening and closing plate, a dispersion mechanism and a conveying mechanism, the feeding port is embedded in the top middle end of the barrel and is connected in a penetrating mode, the inside upper end of the barrel is hinged to the outside upper end of the opening and closing plate through the torsion shaft, the opening and closing plate is located below the feeding port and above the dispersion mechanism, the dispersion mechanism is installed at the middle upper end of the inside of the barrel, the dispersion mechanism is located above the conveying mechanism, and the conveying mechanism is installed at the lower end of the barrel, the right lower end of the barrel is fixed to the left end of the screening machine and is connected in a penetrating mode, the torsion shaft and the opening and closing plate are both provided with two and are symmetrically installed, the two opening and closing plates form an open "V" shaped structure, and the dispersion mechanism is provided with four and is distributed in a two-by-two matrix.

[0005] As a further improvement of the application, the dispersion mechanism comprises an electric rotating shaft, a belt, a cam and a swing mechanism, the electric rotating shaft is installed at the middle end of the inside of the barrel, the output end shaft center end of the electric rotating shaft is synchronously rotated with the cam shaft center end through the belt, the upper end of the cam is in abutment with the middle bottom end of the swing mechanism, the swing mechanism is located at the middle upper end of the inside of the barrel, the electric rotating shaft is a double-shaft structure, one belt is connected to each shaft of the electric rotating shaft, one cam is installed at the left and right ends of the belt, and the cams on the two sides are reversely installed.

[0006] As a further improvement of the application, the swing mechanism comprises a swing frame, a dispersion rod, a connecting shaft, the cam upper end is in contact with the middle end of the swing frame bottom, and the connecting shaft is installed inside the swing frame, the connecting shaft penetrates the inside of the dispersion rod in clearance fit, the dispersion rod is provided with eleven, transversely and equidistantly distributed inside the swing frame, and has a triangular prism structure with the sharp corner end in the upper position.

[0007] As a further improvement of the application, the conveying mechanism comprises a motor, a belt pulley, a conveying belt, a conveying threaded rod, and a wall scraping mechanism, the motor is installed at the lower left end outside the barrel, the belt pulley is provided with two, connected with the motor and the conveying threaded rod respectively, the conveying belt is in transmission connection with the belt pulley, the conveying threaded rod is installed at the lower end inside the barrel, and the inside of the conveying threaded rod is welded with the wall scraping mechanism, the wall scraping mechanism is provided with six, three in a group, and symmetrically installed at the thread blade connection of the conveying threaded rod.

[0008] As a further improvement of the application, the wall scraping mechanism comprises a fixed rod, a spring pipe sleeve, and a scraper, one end of the fixed rod is welded on the surface of the conveying threaded rod, and the other end of the fixed rod is installed in the inside of the spring pipe sleeve in clearance fit, the spring pipe sleeve is welded with the inside middle end of the scraper, the scraper is located inside the conveying threaded rod, and the cross section of the scraper is in "U" type structure.

[0009] 1. The powder raw material is put into the inside of the barrel from the feeding port, after the putting is completed, the opening and closing plate is automatically reset under the action of the reset elastic force of the torsion shaft, the feeding port is closed, and the powder is prevented from floating upward and floating out of the inside of the feeding port again;

[0010] 2. The rotation of the electric rotating shaft makes the two cams reverse the lifting and lowering of the left and right ends of the swing mechanism, the swing mechanism contacts the powder raw material, the dispersion rod improves the effective dispersion of the powder raw material, avoids the phenomenon that the powder raw material is clumped, prevents the powder raw material from being treated as impurities, and improves the precision of screening;

[0011] 3. The conveying threaded rod rotates at the lower end inside the barrel to convey the powder raw material into the inside of the screening machine, under the elastic cooperation of the fixed rod and the spring pipe sleeve, the scraper can move up and down at the thread blade gap of the conveying threaded rod, and the powder raw material remaining at the bottom of the barrel is avoided to be difficult to be discharged into the screening machine for further screening work. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 It is a structure schematic view of the raw material screening device for gene drug research and development.

[0013] Figure 2It is the internal structure schematic view of the feeding mechanism of the application.

[0014] Figure 3 It is the structure schematic view of the dispersion mechanism and the three-dimensional split structure of the application.

[0015] Figure 4 It is the structure schematic view of the swing mechanism of the application in the partial working state.

[0016] Figure 5 It is the structure schematic view of the conveying mechanism of the application.

[0017] Figure 6 It is the structure schematic view of the wall scraping mechanism of the application.

[0018] In the figure: feeding mechanism-S, screening machine-T, support frame-Z, discharge port-P, feeding port-s8, barrel-s6, torsion shaft-s3, opening and closing plate-s1, dispersion mechanism-s5, conveying mechanism-s9, electric rotating shaft-s54, belt-s56, cam-s51, swing mechanism-s58, swing frame-8k, dispersion rod-8b, connecting shaft-8z, motor-s96, pulley-s92, conveying belt-s99, conveying threaded rod-s94, wall scraping mechanism-s91, fixed rod-1z, spring pipe sleeve-1t, scraper-1g. DETAILED DESCRIPTION

[0019] The application is further described below in combination with the drawings: EMBODIMENT

[0020] As shown in the drawings Figure 1 to the drawings Figure 4 shown:

[0021] The application discloses a raw material screening device for genetic drug research and development, which comprises a feeding mechanism S, a screening machine T, a support frame Z and a discharge port P.

[0022] The feeding mechanism S comprises a feeding port s8, a barrel s6, a torsion shaft s3, an opening and closing plate s1, a dispersion mechanism s5 and a conveying mechanism s9. The feeding port s8 is embedded in the top middle end of the barrel s6 and is connected through. The inside upper end of the barrel s6 is hinged to the outside upper end of the opening and closing plate s1 through the torsion shaft s3. The opening and closing plate s1 is located below the feeding port s8 and above the dispersion mechanism s5. The dispersion mechanism s5 is installed in the inside middle upper end of the barrel s6 and is located above the conveying mechanism s9. The conveying mechanism s9 is installed at the lower end of the barrel s6. The right lower end of the barrel s6 is fixed to the left end of the screening machine T and is connected through.

[0023] The torsion shaft s3 and the opening and closing plate s1 are both provided with two and are symmetrically installed, the two opening and closing plates s1 form an open "V" shape structure, the bottom of the two opening and closing plates s1 can allow the raw materials to flow, so that the raw materials all enter the inside of the barrel s6 and cannot float up and float out from the inside of the feeding port s8 again, the dispersion mechanism s5 is provided with four and is distributed in a two-by-two matrix, the powder raw materials can be fully dispersed by the four dispersion mechanisms s5, and the phenomenon of clumping of the powder raw materials is avoided.

[0024] The dispersion mechanism s5 includes an electric rotating shaft s54, a belt s56, a cam s51 and a swing mechanism s58, the electric rotating shaft s54 is installed in the middle end of the barrel s6, and the output end shaft center end of the electric rotating shaft s54 is synchronously rotated with the shaft center end of the cam s51 through the belt s56, the upper end of the cam s51 abuts against the middle end of the bottom of the swing mechanism s58, and the swing mechanism s58 is located in the middle upper end of the barrel s6.

[0025] The electric rotating shaft s54 is a double-shaft structure, one belt is connected to each shaft of the electric rotating shaft s54, and one cam s51 is installed at the left and right ends of the belt, the two cams s51 are reversely installed, the two cams s51 can reversely lift and lower the left and right ends of the bottom of the swing mechanism s58 through the rotation of the electric rotating shaft s54, the swing mechanism s58 is repeatedly swung left and right, and the powder raw materials are swung and contacted.

[0026] The swing mechanism s58 includes a swing frame 8k, a dispersion rod 8b and a connecting shaft 8z, the upper end of the cam s51 abuts against the middle end of the bottom of the swing frame 8k, the connecting shaft 8z is installed in the inner side of the swing frame 8k, and the connecting shaft 8z penetrates through the inside of the dispersion rod 8b in a clearance fit.

[0027] The dispersion rod 8b is provided with eleven and is transversely and equidistantly distributed in the inner side of the swing frame 8k, and has a triangular prism structure, the sharp corner end is located at the upper position, and is installed in a clearance fit with the connecting shaft 8z, so that the dispersion rod 8b can be freely swung in an angle during the swinging of the swing frame 8k, and the powder raw materials are effectively dispersed by the dispersion rod 8b.

[0028] The specific use mode and effect of the embodiment are as follows:

[0029] In the application, the powdery raw materials are put into the barrel s6 from the feeding port s8. During the process of putting, the opening and closing plate s1 swings downward to make the powder smoothly enter the barrel s6. After the putting is completed, the opening and closing plate s1 is automatically reset under the action of the reset elastic force of the torsion shaft s3, so that the feeding port s8 is closed to prevent the powder from floating upward and floating out of the feeding port s8 again. The powder in the barrel s6 contacts the swinging mechanism s58. Through the rotation of the electric rotating shaft s54 and the transmission of the belt s56, the two cams s51 oppositely lift and lower the left and right ends of the swinging mechanism s58, so that the swinging mechanism s58 swings left and right repeatedly, thereby the powdery raw materials are contacted and swung. During the repeated left and right swinging of the swinging frame 8k, the clearance mounting of the connecting shaft 8z and the dispersion rod 8b enables the dispersion rod 8b to swing freely in angle, improves the effective dispersion of the powdery raw materials by the dispersion rod 8b, avoids the phenomenon of clumping of the powdery raw materials, prevents the powdery raw materials from being treated as impurities, and improves the precision of screening. Embodiment

[0030] As shown in the accompanying Figure 5 to the accompanying Figure 6 drawings:

[0031] The conveying mechanism s9 includes a motor s96, a belt pulley s92, a conveying belt s99, a conveying threaded rod s94, and a wall scraping mechanism s91. The motor s96 is installed at the lower left end outside the barrel s6. The belt pulley s92 is provided with two, which are connected with the motor s96 and the conveying threaded rod s94, respectively. The conveying belt s99 is in transmission connection with the belt pulley s92. The conveying threaded rod s94 is installed at the lower end inside the barrel s6, and the inner side of the conveying threaded rod s94 is welded with the wall scraping mechanism s91.

[0032] The wall scraping mechanism s91 is provided with six, and three are a group, which are symmetrically installed at the thread blade connection of the conveying threaded rod s94, so as to comprehensively scrape the powder leaked from the thread blade gap of the conveying threaded rod s94, and avoid that the powdery raw materials are difficult to be discharged to the inside of the screening machine T for further screening work.

[0033] The wall scraping mechanism s91 includes a fixed rod 1z, a spring pipe sleeve 1t, and a scraper 1g. One end of the fixed rod 1z is welded on the surface of the conveying threaded rod s94, and the other end of the fixed rod 1z is gap-fittedly installed in the inside of the spring pipe sleeve 1t. The spring pipe sleeve 1t is welded with the inner middle end of the scraper 1g. The scraper 1g is located in the inside of the conveying threaded rod s94.

[0034] The scraper 1g is in a "U" type structure, and under the elastic expansion cooperation of the fixed rod 1z and the spring sleeve 1t, the scraper 1g can move up and down at the thread blade gap of the conveying thread rod s94, so as to effectively scrape the powdery raw materials.

[0035] The specific use mode and role of the embodiment are as follows:

[0036] In the present application, the dispersed powdery raw materials continue to fall inside the barrel s6 and contact the conveying mechanism s9, and under the rotation of the motor s96, the powdery raw materials are conveyed into the inside of the screening machine T through the transmission of the belt pulley s92 and the conveying belt s99, and the rotation of the conveying thread rod s94 at the lower end of the barrel s6. During the conveying process, the scraper wall mechanism s91 is driven to rotate by the conveying thread rod s94, and under the elastic cooperation of the fixed rod 1z and the spring sleeve 1t on the scraper wall mechanism s91, the scraper 1g can move up and down at the thread blade gap of the conveying thread rod s94, so as to effectively scrape the powdery raw materials, and avoid the powdery raw materials remaining at the bottom of the barrel s6 and being difficult to be discharged into the screening machine T for further screening work.

[0037] The technical solutions of the present application or the technical solutions of the present application are used to design similar technical solutions, and the above technical effects are achieved, which are all within the protection scope of the present application.

Claims

1. A raw material screening device for gene drug development, comprising a feeding mechanism (S), a screening machine (T), a support frame (Z), and a discharge port (P), characterized in that: The feeding mechanism (S) is installed at the right end of the screening machine (T), and a support frame (Z) is welded to the bottom of the screening machine (T). The discharge port (P) is embedded in the bottom of the screening machine (T) and is connected through it. The feeding mechanism (S) includes a feed inlet (S8), a cylinder (S6), a torsion shaft (S3), an opening and closing plate (S1), a dispersing mechanism (S5), and a conveying mechanism (S9). The feed inlet (S8) is embedded in the middle of the top of the cylinder (S6) and is connected through it. The upper end of the inside of the cylinder (S6) is hinged to the upper end of the outer side of the opening and closing plate (S1) through the torsion shaft (S3). The opening and closing plate (S1) is located below the feed inlet (S8) and above the dispersing mechanism (S5). The dispersing mechanism (S5) is installed in the upper middle part of the inside of the cylinder (S6) and is located above the conveying mechanism (S9). The conveying mechanism (S9) is installed at the lower end of the cylinder (S6). The lower right end of the cylinder (S6) is fixed to and connected through the left end of the screening machine (T). The dispersing mechanism (s5) includes an electric shaft (s54), a belt (s56), a cam (s51), and a swing mechanism (s58). The electric shaft (s54) is installed in the middle of the inside of the material cylinder (s6), and the output shaft of the electric shaft (s54) rotates synchronously with the shaft of the cam (s51) via the belt (s56). The upper end of the cam (s51) abuts against the bottom middle of the swing mechanism (s58), which is located in the upper middle part of the inside of the material cylinder (s6). The electric rotating shaft (s54) has a dual-shaft structure, and both shafts of the electric rotating shaft (s54) are connected to a belt. A cam (s51) is installed at both ends of the belt. The cams (s51) on both sides are installed in opposite directions. By rotating the electric rotating shaft (s54), the two cams (s51) can lift and lower the bottom left and right ends of the swing mechanism (s58) in opposite directions, so that the swing mechanism (s58) swings repeatedly from left to right, thereby swinging and contacting the powdered raw material. The swing mechanism (s58) includes a swing frame (8k), a dispersing rod (8b), and a connecting shaft (8z). The upper end of the cam (s51) abuts against the middle of the bottom of the swing frame (8k), and the connecting shaft (8z) is installed inside the swing frame (8k). The connecting shaft (8z) is fitted through the dispersing rod (8b) with a clearance fit. There are eleven dispersing rods (8b), which are distributed horizontally and equally spaced inside the swing frame (8k) and have a triangular prism structure with the pointed end at the top. The gap fit with the connecting shaft (8z) allows the dispersing rod (8b) to swing freely at an angle during the swing of the swing frame (8k), thereby improving the effective dispersion of powdered raw materials by the dispersing rod (8b). The conveying mechanism (s9) includes a motor (s96), a pulley (s92), a conveyor belt (s99), a conveying threaded rod (s94), and a wall scraping mechanism (s91). The motor (s96) is installed on the lower left side of the material cylinder (s6). There are two pulleys (s92), which are connected to the motor (s96) and the conveying threaded rod (s94) respectively. The conveyor belt (s99) is connected to the pulleys (s92) for transmission. The conveying threaded rod (s94) is installed on the lower inside of the material cylinder (s6), and the wall scraping mechanism (s91) is welded to the inner side of the conveying threaded rod (s94). The wall scraping mechanism (s91) includes a fixed rod (1z), a spring sleeve (1t), and a scraper (1g). One end of the fixed rod (1z) is welded to the surface of the conveying threaded rod (s94), and the other end of the fixed rod (1z) is installed inside the spring sleeve (1t) with a clearance fit. The spring sleeve (1t) is welded to the middle of the inner side of the scraper (1g), and the scraper (1g) is located inside the conveying threaded rod (s94).

Citation Information

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